@article{MirskovaAdamovichMirskovetal.2013, author = {Mirskova, Anna N. and Adamovich, Sergey N. and Mirskov, Rudolf G. and Schilde, Uwe}, title = {Reaction of pharmacological active tris-(2-hydroxyethyl)ammonium 4-chlorophenylsulfanylacetate with ZnCl2 or NiCl2: first conversion of a protic ionic liquid into metallated ionic liquid}, series = {CHEMISTRY CENTRAL JOURNAL}, volume = {7}, journal = {CHEMISTRY CENTRAL JOURNAL}, publisher = {BIOMED CENTRAL LTD}, address = {LONDON}, issn = {1752-153X}, doi = {10.1186/1752-153X-7-34}, pages = {5}, year = {2013}, abstract = {The reaction of pharmacological active protic ionic liquid tris-(2-hydroxyethyl)ammonium 4-chlorophenylsulfanylacetate H+N(CH2CH2OH)(3) center dot (-OOCCH2SC6H4Cl-4) (1) with zinc or nickel chloride in a ratio of 2:1 affords stable at room temperature powder-like adducts [H+N(CH2CH2OH)(3)](2) center dot [M(OOCCH2SC6H4Cl-4)(2)Cl-2](2-), M = Zn (2), Ni (3). By recrystallization from aqueous alcohol compound 2 unexpectedly gives Zn(OOCCH2SC6H4Cl-4)(2) center dot 2H(2)O (4). Unlike 2, compound 3 gives crystals [N(CH2CH2OH)(3)](2)Ni2+ center dot [-OOCCH2SC6H4Cl-4](2) (5), which have a structure of metallated ionic liquid. The structure of 5 has been proved by X-ray diffraction analysis. It is the first example of the conversion of a protic ionic liquid into potentially biological active metallated ionic liquid (1 -> 3 -> 5).}, language = {en} } @article{DahlRadonBuehningetal.2013, author = {Dahl, Jan-Ulrik and Radon, Christin and B{\"u}hning, Martin and Nimtz, Manfred and Leichert, Lars I. and Denis, Yann and Jourlin-Castelli, Cecile and Iobbi-Nivol, Chantal and Mejean, Vincent and Leimk{\"u}hler, Silke}, title = {The Sulfur Carrier Protein TusA Has a Pleiotropic Role in Escherichia coli That Also Affects Molybdenum Cofactor Biosynthesis}, series = {JOURNAL OF BIOLOGICAL CHEMISTRY}, volume = {288}, journal = {JOURNAL OF BIOLOGICAL CHEMISTRY}, number = {8}, publisher = {AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC}, address = {BETHESDA}, issn = {0021-9258}, doi = {10.1074/jbc.M112.431569}, pages = {5426 -- 5442}, year = {2013}, abstract = {The Escherichia coli L-cysteine desulfurase IscS mobilizes sulfur from L-cysteine for the synthesis of several biomolecules such as iron-sulfur (FeS) clusters, molybdopterin, thiamin, lipoic acid, biotin, and the thiolation of tRNAs. The sulfur transfer from IscS to various biomolecules is mediated by different interaction partners (e.g. TusA for thiomodification of tRNAs, IscU for FeS cluster biogenesis, and ThiI for thiamine biosynthesis/tRNA thiolation), which bind at different sites of IscS. Transcriptomic and proteomic studies of a Delta tusA strain showed that the expression of genes of the moaABCDE operon coding for proteins involved in molybdenum cofactor biosynthesis is increased under aerobic and anaerobic conditions. Additionally, under anaerobic conditions the expression of genes encoding hydrogenase 3 and several molybdoenzymes such as nitrate reductase were also increased. On the contrary, the activity of all molydoenzymes analyzed was significantly reduced in the Delta tusA mutant. Characterization of the Delta tusA strain under aerobic conditions showed an overall low molybdopterin content and an accumulation of cyclic pyranopterin monophosphate. Under anaerobic conditions the activity of nitrate reductase was reduced by only 50\%, showing that TusA is not essential for molybdenum cofactor biosynthesis. We present a model in which we propose that the direction of sulfur transfer for each sulfur-containing biomolecule is regulated by the availability of the interaction partner of IscS. We propose that in the absence of TusA, more IscS is available for FeS cluster biosynthesis and that the overproduction of FeS clusters leads to a modified expression of several genes.}, language = {en} } @article{InalKoelschChiappisietal.2013, author = {Inal, Sahika and Koelsch, Jonas D. and Chiappisi, Leonardo and Kraft, Mario and Gutacker, Andrea and Janietz, Dietmar and Scherf, Ullrich and Gradzielski, Michael and Laschewsky, Andr{\´e} and Neher, Dieter}, title = {Temperature-Regulated Fluorescence Characteristics of Supramolecular Assemblies Formed By a Smart Polymer and a Conjugated Polyelectrolyte}, series = {MACROMOLECULAR CHEMISTRY AND PHYSICS}, volume = {214}, journal = {MACROMOLECULAR CHEMISTRY AND PHYSICS}, number = {4}, publisher = {WILEY-V C H VERLAG GMBH}, address = {WEINHEIM}, issn = {1022-1352}, doi = {10.1002/macp.201200493}, pages = {435 -- 445}, year = {2013}, abstract = {Aqueous mixtures of a coumarin-labeled non-ionic thermoresponsive copolymer and a cationic polythiophene exhibit marked changes in their fluorescence properties upon heating. At room temperature, emission from the label is significantly quenched due to energy transfer to the conjugated polyelectrolyte. Heating the mixture reduces the energy-transfer efficiency markedly, resulting in a clearly visible change of the emission color. Although the two macromolecules associate strongly at room temperature, the number of interacting sites is largely reduced upon the phase transition. Crucially, the intermolecular association does not suppress the responsiveness of the smart polymer, meaning that this concept should be applicable to chemo- or bioresponsive polymers with optical read-out, for example, as a sensor device.}, language = {en} } @article{WinklerKofodKrastevetal.2013, author = {Winkler, M. and Kofod, G. and Krastev, R. and Stoeckle, S. and Abel, M. W.}, title = {Exponentially Fast Thinning of Nanoscale Films by Turbulent Mixing}, series = {PHYSICAL REVIEW LETTERS}, volume = {110}, journal = {PHYSICAL REVIEW LETTERS}, number = {9}, publisher = {AMER PHYSICAL SOC}, address = {COLLEGE PK}, issn = {0031-9007}, doi = {10.1103/PhysRevLett.110.094501}, pages = {5}, year = {2013}, abstract = {Films are nanoscopic elements of foams, emulsions, and suspensions that form a paradigm for nanochannel transport that eventually tests the limits of hydrodynamic descriptions. Here, we study the collapse of a freestanding film to its equilibrium. The generation of nanoscale films usually is a slow linear process; using thermal forcing we find unprecedented dynamics with exponentially fast thinning. The complex interplay of thermal convection, interface, and gravitational forces yields optimal turbulent mixing and transport. Domains of collapsed film are generated, elongated, and convected in a beautiful display of chaotic mixing. With a time scale analysis, we identify mixing as the dominant dynamical process responsible for exponential thinning. DOI: 10.1103/PhysRevLett.110.094501}, language = {en} } @article{SchickBojahrHerzogetal.2013, author = {Schick, Daniel and Bojahr, Andre and Herzog, Marc and Gaal, P. and Vrejoiu, I. and Bargheer, Matias}, title = {Following Strain-Induced Mosaicity Changes of Ferroelectric Thin Films by Ultrafast Reciprocal Space Mapping}, series = {Physical review letters}, volume = {110}, journal = {Physical review letters}, number = {9}, publisher = {American Physical Society}, address = {College Park}, issn = {0031-9007}, doi = {10.1103/PhysRevLett.110.095502}, pages = {5}, year = {2013}, abstract = {We investigate coherent phonon propagation in a thin film of ferroelectric PbZr0.2Ti0.8O3 (PZT) by ultrafast x-ray diffraction experiments, which are analyzed as time-resolved reciprocal space mapping in order to observe the in-and out-of-plane structural dynamics, simultaneously. The mosaic structure of the PZT leads to a coupling of the excited out-of-plane expansion to in-plane lattice dynamics on a picosecond time scale, which is not observed for out-of-plane compression.}, language = {en} } @article{EliazarMetzler2013, author = {Eliazar, Iddo and Metzler, Ralf}, title = {Anomalous statistics of random relaxations in random environments}, series = {Physical review : E, Statistical, nonlinear and soft matter physics}, volume = {87}, journal = {Physical review : E, Statistical, nonlinear and soft matter physics}, number = {2}, publisher = {American Physical Society}, address = {College Park}, issn = {1539-3755}, doi = {10.1103/PhysRevE.87.022141}, pages = {12}, year = {2013}, abstract = {We comprehensively analyze the emergence of anomalous statistics in the context of the random relaxation ( RARE) model [Eliazar and Metzler, J. Chem. Phys. 137, 234106 ( 2012)], a recently introduced versatile model of random relaxations in random environments. The RARE model considers excitations scattered randomly across a metric space around a reaction center. The excitations react randomly with the center, the reaction rates depending on the excitations' distances from this center. Relaxation occurs upon the first reaction between an excitation and the center. Addressing both the relaxation time and the relaxation range, we explore when these random variables display anomalous statistics, namely, heavy tails at zero and at infinity that manifest, respectively, exceptionally high occurrence probabilities of very small and very large outliers. A cohesive set of closed-form analytic results is established, determining precisely when such anomalous statistics emerge.}, language = {en} } @article{FeudelSeehaferTuckermanetal.2013, author = {Feudel, Fred and Seehafer, Norbert and Tuckerman, Laurette S. and Gellert, Marcus}, title = {Multistability in rotating spherical shell convection}, series = {Physical review : E, Statistical, nonlinear and soft matter physics}, volume = {87}, journal = {Physical review : E, Statistical, nonlinear and soft matter physics}, number = {2}, publisher = {American Physical Society}, address = {College Park}, issn = {1539-3755}, doi = {10.1103/PhysRevE.87.023021}, pages = {8}, year = {2013}, abstract = {The multiplicity of stable convection patterns in a rotating spherical fluid shell heated from the inner boundary and driven by a central gravity field is presented. These solution branches that arise as rotating waves (RWs) are traced for varying Rayleigh number while their symmetry, stability, and bifurcations are studied. At increased Rayleigh numbers all the RWs undergo transitions to modulated rotating waves (MRWs) which are classified by their spatiotemporal symmetry. The generation of a third frequency for some of the MRWs is accompanied by a further loss of symmetry. Eventually a variety of MRWs, three-frequency solutions, and chaotic saddles and attractors control the dynamics for higher Rayleigh numbers.}, language = {en} } @article{LinBergerGrimmetal.2013, author = {Lin, Yue and Berger, Uta and Grimm, Volker and Huth, Franka and Weiner, Jacob}, title = {Plant interactions alter the predictions of metabolic scaling theory}, series = {PLoS one}, volume = {8}, journal = {PLoS one}, number = {2}, publisher = {PLoS}, address = {San Fransisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0057612}, pages = {6}, year = {2013}, abstract = {Metabolic scaling theory (MST) is an attempt to link physiological processes of individual organisms with macroecology. It predicts a power law relationship with an exponent of -4/3 between mean individual biomass and density during density-dependent mortality (self-thinning). Empirical tests have produced variable results, and the validity of MST is intensely debated. MST focuses on organisms' internal physiological mechanisms but we hypothesize that ecological interactions can be more important in determining plant mass-density relationships induced by density. We employ an individual-based model of plant stand development that includes three elements: a model of individual plant growth based on MST, different modes of local competition (size-symmetric vs. -asymmetric), and different resource levels. Our model is consistent with the observed variation in the slopes of self-thinning trajectories. Slopes were significantly shallower than -4/3 if competition was size-symmetric. We conclude that when the size of survivors is influenced by strong ecological interactions, these can override predictions of MST, whereas when surviving plants are less affected by interactions, individual-level metabolic processes can scale up to the population level. MST, like thermodynamics or biomechanics, sets limits within which organisms can live and function, but there may be stronger limits determined by ecological interactions. In such cases MST will not be predictive.}, language = {en} } @article{BauerSommerGaedke2013, author = {Bauer, Barbara and Sommer, Ulrich and Gaedke, Ursula}, title = {High predictability of spring phytoplankton biomass in mesocosms at the species, functional group and community level}, series = {Freshwater biology}, volume = {58}, journal = {Freshwater biology}, number = {3}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0046-5070}, doi = {10.1111/j.1365-2427.2012.02780.x}, pages = {588 -- 596}, year = {2013}, abstract = {1. Models aim to predict phytoplankton dynamics based on observed initial conditions and a set of equations and parameters. However, our knowledge about initial conditions in nature is never perfect. Thus, if phytoplankton dynamics are sensitive to small variations in initial conditions, they are difficult to predict. 2. We used time-series data from indoor mesocosm experiments with natural phyto- and zooplankton communities to quantify the extent to which small initial differences in the species, functional group and community biomass in parallel treatments were amplified or buffered over time. We compared the differences in dynamics between replicates and among all mesocosms of 1year. 3. Temperature-sensitive grazing during the exponential growth phase of phytoplankton caused divergence. In contrast, negative density dependence caused convergence. 4. Mean differences in biomass between replicates were similar for all hierarchical levels. This indicates that differences in their initial conditions were amplified to the same extent. Even though large differences in biomass occasionally occurred between replicates for a short time, dynamics returned to the same path at all hierarchical levels. This suggests that internal feedback mechanisms make the spring development of phytoplankton highly predictable.}, language = {en} } @article{ZakharovaNikoloskiKoseska2013, author = {Zakharova, A. and Nikoloski, Zoran and Koseska, Aneta}, title = {Dimensionality reduction of bistable biological systems}, series = {Bulletin of mathematical biology : official journal of the Society for Mathematical Biology}, volume = {75}, journal = {Bulletin of mathematical biology : official journal of the Society for Mathematical Biology}, number = {3}, publisher = {Springer}, address = {New York}, issn = {0092-8240}, doi = {10.1007/s11538-013-9807-8}, pages = {373 -- 392}, year = {2013}, abstract = {Time hierarchies, arising as a result of interactions between system's components, represent a ubiquitous property of dynamical biological systems. In addition, biological systems have been attributed switch-like properties modulating the response to various stimuli across different organisms and environmental conditions. Therefore, establishing the interplay between these features of system dynamics renders itself a challenging question of practical interest in biology. Existing methods are suitable for systems with one stable steady state employed as a well-defined reference. In such systems, the characterization of the time hierarchies has already been used for determining the components that contribute to the dynamics of biological systems. However, the application of these methods to bistable nonlinear systems is impeded due to their inherent dependence on the reference state, which in this case is no longer unique. Here, we extend the applicability of the reference-state analysis by proposing, analyzing, and applying a novel method, which allows investigation of the time hierarchies in systems exhibiting bistability. The proposed method is in turn used in identifying the components, other than reactions, which determine the systemic dynamical properties. We demonstrate that in biological systems of varying levels of complexity and spanning different biological levels, the method can be effectively employed for model simplification while ensuring preservation of qualitative dynamical properties (i.e., bistability). Finally, by establishing a connection between techniques from nonlinear dynamics and multivariate statistics, the proposed approach provides the basis for extending reference-based analysis to bistable systems.}, language = {en} } @article{OskinovaSunEvansetal.2013, author = {Oskinova, Lida and Sun, W. and Evans, C. J. and Henault-Brunet, V. and Chu, Y.-H. and Gallagher, J. S. and Guerrero, Mart{\´i}n A. and Gruendl, R. A. and G{\"u}del, M. and Silich, S. and Chen, Y. and Naze, Y. and Hainich, Rainer and Reyes-Iturbide, J.}, title = {Discovery of x-ray emission from young suns in the small magellanic cloud}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {765}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.1088/0004-637X/765/1/73}, pages = {12}, year = {2013}, abstract = {We report the discovery of extended X-ray emission within the young star cluster NGC 602a in the Wing of the Small Magellanic Cloud (SMC) based on observations obtained with the Chandra X-Ray Observatory. X-ray emission is detected from the cluster core area with the highest stellar density and from a dusty ridge surrounding the H II region. We use a census of massive stars in the cluster to demonstrate that a cluster wind or wind-blown bubble is unlikely to provide a significant contribution to the X-ray emission detected from the central area of the cluster. We therefore suggest that X-ray emission at the cluster core originates from an ensemble of low-and solar-mass pre-main-sequence (PMS) stars, each of which would be too weak in X-rays to be detected individually. We attribute the X-ray emission from the dusty ridge to the embedded tight cluster of the newborn stars known in this area from infrared studies. Assuming that the levels of X-ray activity in young stars in the low-metallicity environment of NGC 602a are comparable to their Galactic counterparts, then the detected spatial distribution, spectral properties, and level of X-ray emission are largely consistent with those expected from low-and solar-mass PMS stars and young stellar objects (YSOs). This is the first discovery of X-ray emission attributable to PMS stars and YSOs in the SMC, which suggests that the accretion and dynamo processes in young, low-mass objects in the SMC resemble those in the Galaxy.}, language = {en} } @article{Kroll2013, author = {Kroll, Alexander}, title = {The other type of performance information - nonroutine feedback, its relevance and use}, series = {Public administration review}, volume = {73}, journal = {Public administration review}, number = {2}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0033-3352}, doi = {10.1111/j.1540-6210.2012.02648.x}, pages = {265 -- 276}, year = {2013}, abstract = {The literature on performance information use explains how public managers deal with mainly quantitative data that are systematically collected and formally reported. This article argues that such a narrow understanding is incomplete, as it excludes all kinds of nonroutine performance information, including verbal, ad hoc, and qualitative feedback. To understand how responsive public managers are to performance feedback, alternative sources of performance information need to be taken into account. A literature review suggests considering two important sources of nonroutine feedback: organizational insiders and relevant external stakeholders. Using survey data from German local government, this article shows that public managers prefer to use nonroutine feedback over routine data from performance reports. Furthermore, a regression analysis indicates that different sources of performance information require different determinants to trigger their use. This finding is essential because it suggests that explanations of performance information use can covary with the information source studied.}, language = {en} } @article{SpeckRaeuberKuekenshoeneretal.2013, author = {Speck, Janina and R{\"a}uber, Christina and K{\"u}kensh{\"o}ner, Tim and Niem{\"o}ller, Christoph and Mueller, Katelyn J. and Schleberger, Paula and Dondapati, Padmarupa and Hecky, Jochen and Arndt, Katja Maren and M{\"u}ller, Kristian M.}, title = {TAT hitchhiker selection expanded to folding helpers, multimeric interactions and combinations with protein fragment complementation}, series = {Protein engineering design \& selection}, volume = {26}, journal = {Protein engineering design \& selection}, number = {3}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {1741-0126}, doi = {10.1093/protein/gzs098}, pages = {225 -- 242}, year = {2013}, abstract = {The twin-arginine translocation (TAT) pathway of the bacterial cytoplasmic membrane mediates translocation only of proteins that accomplished a native-like conformation. We deploy this feature in modular selection systems for directed evolution, in which folding helpers as well as dimeric or oligomeric proteinprotein interactions enable TAT-dependent translocation of the resistance marker TEM -lactamase (L). Specifically, we demonstrate and analyze selection of (i) enhancers for folding by direct TAT translocation selection of a target protein interposed between the TorA signal sequence and L, (ii) dimeric or oligomeric proteinprotein interactions by hitchhiker translocation (HiT) selection of proteins fused to the TorA signal sequence and to the L, respectively and (iii) heterotrimeric proteinprotein interactions by combining HiT with protein fragment complementation selection of proteins fused to two split L fragments and TorA, respectively. The lactamase fragments were additionally engineered for improved activity and stability. Applicability was benchmarked with interaction partners of known affinity and multimerization whereby cellular fitness correlated well with biophysical protein properties. Ultimately, the HiT selection was employed to identify peptides, which specifically bind to leukemia- and melanoma-relevant target proteins (MITF and ETO) by coiled-coil or tetra-helix-bundle formation with high affinity. The various versions of TAT selection led to inhibiting peptides (iPEPs) of disease-promoting interactions and enabled so far difficult to achieve selections.}, language = {en} } @article{HoffmannSeissSpahn2013, author = {Hoffmann, H. and Seiß, Martin and Spahn, Frank}, title = {Vertical relaxation of a moonlet propeller in Saturn's a ring}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, volume = {765}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {2041-8205}, doi = {10.1088/2041-8205/765/1/L4}, pages = {3}, year = {2013}, abstract = {Two images, taken by the Cassini spacecraft near Saturn's equinox in 2009 August, show the Earhart propeller casting a 350 km long shadow, offering the opportunity to watch how the ring height, excited by the propeller moonlet, relaxes to an equilibrium state. From the shape of the shadow cast and a model of the azimuthal propeller height relaxation, we determine the exponential cooling constant of this process to be lambda = 0.07 +/- 0.02 km(-1), and thereby determine the collision frequency of the ring particles in the vertically excited region of the propeller to be omega(c)/Omega = 0.9 +/- 0.2.}, language = {en} } @article{LinklaterMayerSwaisgood2013, author = {Linklater, Wayne L. and Mayer, Katharina and Swaisgood, Ronald R.}, title = {Chemical signals of age, sex and identity in black rhinoceros}, series = {Animal behaviour}, volume = {85}, journal = {Animal behaviour}, number = {3}, publisher = {Elsevier}, address = {London}, issn = {0003-3472}, doi = {10.1016/j.anbehav.2012.12.034}, pages = {671 -- 677}, year = {2013}, abstract = {Olfactory communication may be particularly important to black rhinoceros, Diceros bicornis, because they are solitary living and have comparatively poor eyesight but their populations are structured by inter-and intrasexual relationships. Understanding olfactory functions and processes might achieve better conservation management but their study in rhinoceros remains anecdotal or descriptive. Experimental approaches are required but rarely possible as rhinoceros are difficult to observe and manipulate. We measured the olfactory investigation behaviour (duration and frequency of sniffing) of black rhinoceros in four experiments designed to determine the function of chemosignals in dung and urine. A habituationedishabituation trial demonstrated that black rhinoceros discriminated individually distinctive odours from faecal signals (experiment 1). When adults (>6 years old) were presented with dung from conspecifics of different sex and age classes (adult, and subadult from 2 to 4 years old), male dung was investigated more by both sexes, and females investigated subadult dung more (experiment 2). Both dung and urine from the same adult donors were investigated by both sexes, but male dung was investigated more than female dung and female urine more than male urine, although differences were statistically weak (experiment 3). Lastly, fresh faecal samples and those aged 1, 2, 4, 16 and 32 days were similarly investigated, indicating that they still function as olfactory signals. Together the results indicate that dung or urine signalled age, sex and identity to conspecifics and signals may persist as dung decays. Chemosignals are likely to be important to the social and spatial organization of black rhinoceros.}, language = {en} } @article{KlieglHohensteinYanetal.2013, author = {Kliegl, Reinhold and Hohenstein, Sven and Yan, Ming and McDonald, Scott A.}, title = {How preview space/time translates into preview cost/benefit for fixation durations during reading}, series = {The quarterly journal of experimental psychology}, volume = {66}, journal = {The quarterly journal of experimental psychology}, number = {3}, publisher = {Wiley}, address = {Hove}, issn = {1747-0218}, doi = {10.1080/17470218.2012.658073}, pages = {581 -- 600}, year = {2013}, abstract = {Eye-movement control during reading depends on foveal and parafoveal information. If the parafoveal preview of the next word is suppressed, reading is less efficient. A linear mixed model (LMM) reanalysis of McDonald (2006) confirmed his observation that preview benefit may be limited to parafoveal words that have been selected as the saccade target. Going beyond the original analyses, in the same LMM, we examined how the preview effect (i.e., the difference in single-fixation duration, SFD, between random-letter and identical preview) depends on the gaze duration on the pretarget word and on the amplitude of the saccade moving the eye onto the target word. There were two key results: (a) The shorter the saccade amplitude (i.e., the larger preview space), the shorter a subsequent SFD with an identical preview; this association was not observed with a random-letter preview. (b) However, the longer the gaze duration on the pretarget word, the longer the subsequent SFD on the target, with the difference between random-letter string and identical previews increasing with preview time. A third patternincreasing cost of a random-letter string in the parafovea associated with shorter saccade amplitudeswas observed for target gaze durations. Thus, LMMs revealed that preview effects, which are typically summarized under preview benefit, are a complex mixture of preview cost and preview benefit and vary with preview space and preview time. The consequence for reading is that parafoveal preview may not only facilitate, but also interfere with lexical access.}, language = {en} } @article{WotschackKliegl2013, author = {Wotschack, Christiane and Kliegl, Reinhold}, title = {Reading strategy modulates parafoveal-on-foveal effects in sentence reading}, series = {The quarterly journal of experimental psychology}, volume = {66}, journal = {The quarterly journal of experimental psychology}, number = {3}, publisher = {Wiley}, address = {Hove}, issn = {1747-0218}, doi = {10.1080/17470218.2011.625094}, pages = {548 -- 562}, year = {2013}, abstract = {Task demands and individual differences have been linked reliably to word skipping during reading. Such differences in fixation probability may imply a selection effect for multivariate analyses of eye-movement corpora if selection effects correlate with word properties of skipped words. For example, with fewer fixations on short and highly frequent words the power to detect parafoveal-on-foveal effects is reduced. We demonstrate that increasing the fixation probability on function words with a manipulation of the expected difficulty and frequency of questions reduces an age difference in skipping probability (i.e., old adults become comparable to young adults) and helps to uncover significant parafoveal-on-foveal effects in this group of old adults. We discuss implications for the comparison of results of eye-movement research based on multivariate analysis of corpus data with those from display-contingent manipulations of target words.}, language = {en} } @article{GhahghaeiLinnellFischeretal.2013, author = {Ghahghaei, Saeideh and Linnell, Karina J. and Fischer, Martin H. and Dubey, Amit and Davis, Robert}, title = {Effects of load on the time course of attentional engagement, disengagement, and orienting in reading}, series = {The quarterly journal of experimental psychology}, volume = {66}, journal = {The quarterly journal of experimental psychology}, number = {3}, publisher = {Wiley}, address = {Hove}, issn = {1747-0218}, doi = {10.1080/17470218.2011.635795}, pages = {453 -- 470}, year = {2013}, abstract = {We examined how the frequency of the fixated word influences the spatiotemporal distribution of covert attention during reading. Participants discriminated gaze-contingent probes that occurred with different spatial and temporal offsets from randomly chosen fixation points during reading. We found that attention was initially focused at fixation and that subsequent defocusing was slower when the fixated word was lower in frequency. Later in a fixation, attention oriented more towards the next saccadic target for high- than for low-frequency words. These results constitute the first report of the time course of the effect of load on attentional engagement and orienting in reading. They are discussed in the context of serial and parallel models of reading.}, language = {en} } @article{MuehlbauerGollhoferGranacher2013, author = {M{\"u}hlbauer, Thomas and Gollhofer, Albert and Granacher, Urs}, title = {Association of balance, strength, and power measures in young adults}, series = {Journal of strength and conditioning research : the research journal of the NSCA}, volume = {27}, journal = {Journal of strength and conditioning research : the research journal of the NSCA}, number = {3}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {1064-8011}, doi = {10.1097/JSC.0b013e31825c2bab}, pages = {582 -- 589}, year = {2013}, abstract = {Muehlbauer, T, Gollhofer, A, and Granacher, U. Association of balance, strength, and power measures in young adults. J Strength Cond Res 27(3): 582-589, 2013-The purpose of this study was to investigate the relationship between variables of static/dynamic balance, isometric strength, and power. Twenty-seven young healthy adults (mean age: 23 6 4 years) performed measurements of static (unperturbed)/dynamic (perturbed) balance, isometric strength (i.e., maximal isometric torque [MIT]; rate of torque development [RTD] of the plantar flexor), and power (i.e., countermovement jump [CMJ] height and power). No significant associations were found between variables of static and dynamic balance (r = -0.090 to + 0.329, p > 0.05) and between measures of static/dynamic balance and isometric strength (r = +0.041 to +0.387, p > 0.05) and static/dynamic balance and power (r = -0.076 to + 0.218, p > 0.05). Significant positive correlations (r) were detected between variables of power and isometric strength ranging from +0.458 to +0.689 (p, 0.05). Furthermore, simple regression analyses revealed that a 10\% increase in mean CMJ height (4.1 cm) was associated with 22.9 N.m and 128.4 N.m.s(-1) better MIT and RTD, respectively. The nonsignificant correlation between static and dynamic balance measures and between static/dynamic balance, isometric strength, and power variables implies that these capacities may be independent of each other and may have to be tested and trained complementarily.}, language = {en} } @article{RichterSchroederEsselbachHartmannetal.2013, author = {Richter, Dania and Schr{\"o}der-Esselbach, Boris and Hartmann, Niklas K. and Matuschka, Franz-Rainer}, title = {Spatial stratification of various Lyme disease spirochetes in a Central European site}, series = {FEMS microbiology ecology}, volume = {83}, journal = {FEMS microbiology ecology}, number = {3}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0168-6496}, doi = {10.1111/1574-6941.12029}, pages = {738 -- 744}, year = {2013}, abstract = {To determine whether the genospecies composition of Lyme disease spirochetes is spatially stratified, we collected questing Ixodes ricinus ticks in neighboring plots where rodents, birds, and lizards were present as reservoir host and compared the prevalence of various genospecies. The overall prevalence of spirochetes in questing ticks varied across the study site. Borrelia lusitaniae appeared to infect adult ticks in one plot at the same frequency as did Borrelia afzelii in the other plots. The relative density of questing nymphal and adult ticks varied profoundly. Where lizards were exceedingly abundant, these vertebrates seemed to constitute the dominant host for nymphal ticks, contributing the majority of infected adult ticks. Because lizards support solely B.lusitaniae and appear to exclude other genospecies, their narrow genospecies association results in predominance of B.lusitaniae in sites where lizards are abundant, while limiting its spread to the host's habitat range. To the extent that Central European B.lusitaniae strains are nonpathogenic, the presence of numerous lizards should locally decrease risk of infection for people. Evaluation of regional risk of infection by Lyme disease spirochetes should take the spatial effect of hosts into consideration, which stratify the distribution of specifically infected ticks on a small scale.}, language = {en} }