@article{HortobagyiLesinskiGaebleretal.2015, author = {Hortob{\´a}gyi, Tibor and Lesinski, Melanie and G{\"a}bler, Martijn and VanSwearingen, Jessie M. and Malatesta, Davide and Granacher, Urs}, title = {Effects of three types of exercise interventions on healthy old adults' gait speed}, series = {Sports medicine}, volume = {45}, journal = {Sports medicine}, publisher = {Springer}, address = {Berlin}, issn = {1179-2035}, doi = {10.1007/s40279-015-0371-2}, pages = {1627 -- 1643}, year = {2015}, abstract = {Background: Habitual walking speed predicts many clinical conditions later in life, but it declines with age. However, which particular exercise intervention can minimize the age-related gait speed loss is unclear. Purpose: Our objective was to determine the effects of strength, power, coordination, and multimodal exercise training on healthy old adults' habitual and fast gait speed. Methods: We performed a computerized systematic literature search in PubMed and Web of Knowledge from January 1984 up to December 2014. Search terms included 'Resistance training', 'power training', 'coordination training', 'multimodal training', and 'gait speed (outcome term). Inclusion criteria were articles available in full text, publication period over past 30 years, human species, journal articles, clinical trials, randomized controlled trials, English as publication language, and subject age C65 years. The methodological quality of all eligible intervention studies was assessed using the Physiotherapy Evidence Database (PEDro) scale. We computed weighted average standardized mean differences of the intervention-induced adaptations in gait speed using a random-effects model and tested for overall and individual intervention effects relative to no-exercise controls. Results: A total of 42 studies (mean PEDro score of 5.0 +/- 1.2) were included in the analyses (2495 healthy old adults; age 74.2 years [64.4-82.7]; body mass 69.9 +/- 4.9 kg, height 1.64 +/- 0.05 m, body mass index 26.4 +/- 1.9 kg/m(2), and gait speed 1.22 +/- 0.18 m/s). The search identified only one power training study, therefore the subsequent analyses focused only on the effects of resistance, coordination, and multimodal training on gait speed. The three types of intervention improved gait speed in the three experimental groups combined (n = 1297) by 0.10 m/s (+/- 0.12) or 8.4 \% (+/- 9.7), with a large effect size (ES) of 0.84. Resistance (24 studies; n = 613; 0.11 m/s; 9.3 \%; ES: 0.84), coordination (eight studies, n = 198; 0.09 m/s; 7.6 \%; ES: 0.76), and multimodal training (19 studies; n = 486; 0.09 m/s; 8.4 \%, ES: 0.86) increased gait speed statistically and similarly. Conclusions: Commonly used exercise interventions can functionally and clinically increase habitual and fast gait speed and help slow the loss of gait speed or delay its onset.}, language = {en} } @article{Mackert2015, author = {Mackert, J{\"u}rgen}, title = {The secret society of torturers}, series = {Internationale journal of conflict and violence}, volume = {9}, journal = {Internationale journal of conflict and violence}, number = {1}, issn = {1864-1385}, doi = {10.4119/ijcv-3071}, url = {http://nbn-resolving.de/http://nbn-resolving.de/urn:nbn:de:0070-ijcv-2015130}, pages = {106 -- 120}, year = {2015}, abstract = {The Secret Society of Torturers107How do normal people become able to torture others? In order to explain this puzzling social phenomenon, we have to take secrecy - the characteristic trait of modern torture - as the lynchpin of the analysis. Following Georg Simmel's formal analysis of the "secret society", the contribution reconstructs structural and cultural aspects of the secret society of torturers that generate social processes that allow its members to behave extremely violently, forcing individuals to turn into torturers. The contribution argues that the form of social behaviour that we call torture is socially shaped. It goes beyond social psychology to de-velop an explanation from the perspective of relational sociology}, language = {en} } @article{AzodiChengMeinel2015, author = {Azodi, Amir and Cheng, Feng and Meinel, Christoph}, title = {Event Driven Network Topology Discovery and Inventory Listing Using REAMS}, series = {Wireless personal communications : an international journal}, volume = {94}, journal = {Wireless personal communications : an international journal}, publisher = {Springer}, address = {New York}, issn = {0929-6212}, doi = {10.1007/s11277-015-3061-3}, pages = {415 -- 430}, year = {2015}, abstract = {Network Topology Discovery and Inventory Listing are two of the primary features of modern network monitoring systems (NMS). Current NMSs rely heavily on active scanning techniques for discovering and mapping network information. Although this approach works, it introduces some major drawbacks such as the performance impact it can exact, specially in larger network environments. As a consequence, scans are often run less frequently which can result in stale information being presented and used by the network monitoring system. Alternatively, some NMSs rely on their agents being deployed on the hosts they monitor. In this article, we present a new approach to Network Topology Discovery and Network Inventory Listing using only passive monitoring and scanning techniques. The proposed techniques rely solely on the event logs produced by the hosts and network devices present within a network. Finally, we discuss some of the advantages and disadvantages of our approach.}, language = {en} } @article{ConfortiPraRoelly2015, author = {Conforti, Giovanni and Pra, Paolo Dai and Roelly, Sylvie}, title = {Reciprocal Class of Jump Processes}, series = {Journal of theoretical probability}, volume = {30}, journal = {Journal of theoretical probability}, publisher = {Springer}, address = {New York}, issn = {0894-9840}, doi = {10.1007/s10959-015-0655-3}, pages = {551 -- 580}, year = {2015}, abstract = {Processes having the same bridges as a given reference Markov process constitute its reciprocal class. In this paper we study the reciprocal class of compound Poisson processes whose jumps belong to a finite set . We propose a characterization of the reciprocal class as the unique set of probability measures on which a family of time and space transformations induces the same density, expressed in terms of the reciprocal invariants. The geometry of plays a crucial role in the design of the transformations, and we use tools from discrete geometry to obtain an optimal characterization. We deduce explicit conditions for two Markov jump processes to belong to the same class. Finally, we provide a natural interpretation of the invariants as short-time asymptotics for the probability that the reference process makes a cycle around its current state.}, language = {en} } @article{MuellerWieseMayretal.2015, author = {M{\"u}ller, Hans-Georg and Wiese, Heike and Mayr, Katharina and Kr{\"a}mer, Philipp and Seeger, Patrick and Mezger, Verena}, title = {Changing teachers' attitudes towards linguistic diversity}, series = {International Journal of Applied Linguistics}, volume = {27}, journal = {International Journal of Applied Linguistics}, number = {1}, pages = {198 -- 220}, year = {2015}, abstract = {We discuss an intervention programme for kindergarten and school teachers' continuing education in Germany that targets biases against language outside a perceived monolingual 'standard' and its speakers. The programme combines anti-bias methods relating to linguistic diversity with objectives of raising critical language awareness. Evaluation through teachers' workshops in Berlin and Brandenburg points to positive and enduring attitudinal changes in participants, but not in control groups that did not attend workshops, and effects were independent of personal variables gender and teaching subject and only weakly associated with age. We relate these effects to such programme features as indirect and inclusive methods that foster active engagement, and the combination of 'safer' topics targeting attitudes towards linguistic structures with more challenging ones dealing with the discrimination of speakers.}, language = {en} } @article{ZimmermannNey2015, author = {Zimmermann, Andreas and Ney, Martin}, title = {Cyber-Security beyond the military perspective: International Law 'cyber space' and the concept of due diligence.}, series = {German Yearbook of International Law}, volume = {58}, journal = {German Yearbook of International Law}, publisher = {Duncker \& Humblot}, address = {Berlin}, pages = {51 -- 66}, year = {2015}, language = {en} } @article{Demske2015, author = {Demske, Ulrike}, title = {Towards coherent infinitival patterns in the history of German}, series = {The Diachrony of Infinitival Patterns: Their origin, development and loss. In: Journal of Historical Linguistics}, volume = {2015}, journal = {The Diachrony of Infinitival Patterns: Their origin, development and loss. In: Journal of Historical Linguistics}, number = {5.1}, editor = {Demske, Ulrike and Jędrzejowski, Łukasz}, publisher = {Benjamins}, address = {Amsterdam}, issn = {2210-2116 print}, doi = {10.1075/jhl.5.1.01dem}, pages = {6 -- 40}, year = {2015}, abstract = {According to Haider (2010), we have to distinguish three types of infinitival complements in Present-Day German: (i) CP complements, (ii) VP complements and (iii) verbal clusters. While CP complements give rise to biclausal structures, VP complements and verbal clusters indicate a monoclausal structure. Non-finite verbs in verbal clusters build a syntactic unit with the governing verb. It is only the last infinitival pattern that we address as a so-called coherent infinitival pattern, a notion introduced in the influential work of Bech (1955/57). Verbal clusters are bound to languages with an OV grammar, hence the well-known differences regarding infinitival syntax in German and English (Haider 2003, Bobaljik 2004). On the widespread assumption that German has been an OV language throughout its history (Axel 2007), we expect all three types of infinitival complements to be present from the earliest attestions of German.}, language = {en} } @article{VasishthKentner2015, author = {Vasishth, Shravan and Kentner, Gerrit}, title = {Prosodic focus marking in silent reading}, series = {Frontiers in psychology}, volume = {2016}, journal = {Frontiers in psychology}, number = {7}, editor = {Crocker, Matthew W.}, doi = {10.3389/fpsyg.2016.00319}, pages = {1 -- 19}, year = {2015}, abstract = {Understanding a sentence and integrating it into the discourse depends upon the identification of its focus, which, in spoken German, is marked by accentuation. In the case of written language, which lacks explicit cues to accent, readers have to draw on other kinds of information to determine the focus. We study the joint or interactive effects of two kinds of information that have no direct representation in print but have each been shown to be influential in the reader's text comprehension: (i) the (low-level)rhythmic-prosodic structure that is based on the distribution of lexically stressed syllables, and (ii) the (high-level) discourse context that is grounded in the memory of previous linguistic content. Systematically manipulating these factors, we examine the way readers resolve a syntactic ambiguity involving the scopally ambiguous focus operator auch (engl. "too") in both oral (Experiment 1) and silent reading (Experiment 2). The results of both experiments attest that discourse context and local linguistic rhythm conspire to guide the syntactic and, oncomitantly, the focus-structural analysis of ambiguous sentences. We argue that reading comprehension requires the (implicit) assignment of accents according to the focus structure and that, by establishing a prominence profile, the implicit prosodic rhythm directly affects accent assignment.}, language = {en} } @article{Zimmermann2015, author = {Zimmermann, Andreas}, title = {The Palestinian-Israeli Conflict: Developing International Law Without Solving the Conflict}, series = {Archiv des V{\"o}lkerrechts}, volume = {53}, journal = {Archiv des V{\"o}lkerrechts}, number = {2}, publisher = {Mohr Siebeck}, address = {T{\"u}bingen}, doi = {10.1628/000389215X14412717564749}, pages = {149 -- 166}, year = {2015}, abstract = {The article analyses whether the Palestinian-Israeli conflict has served as a catalyst for the development of international law, as well as whether international law has been instrumental in attempting to find solutions for the said conflict. In several ways, this conflict has made a significant contribution to understanding and interpreting the UN Charter. It also brought along important developments about the role of third parties, both under the Geneva Conventions and under the law of state responsibility, which provides for an obligation of not recognizing as legal, or not rendering aid or assistance to situations caused by serious violations of jus cogens. International judicial institutions (and also domestic ones) play a rather limited role in this respect, due both to a lack of courage to address fundamental questions, and/or a disregard of the outcome of the proceedings by at least one of the parties to the conflict. Other reasons are Israel's reluctance of accepting the jurisdiction of either the ICJ or the ICC, and its view on the non-applicability of human rights treaties outside of its territory, as well as Palestine's uncertain status in the international community limiting its access to international courts. However, the ICJ's 2004 (formally non-binding) advisory opinion on the Israeli Wall provided answers to some of the most fundamental questions related to the conflict, unfortunately without having any immediate impact on the situation on the ground. Given Palestine's accession to the Rome Statute in early 2015, time has yet to show which role in the process will be played by the ICC. Other issues arising from the conflict, and examined by this article, are that of (Palestinian) statehood, going beyond the traditional concept of statehood and including the consequences of the jus cogens-character of the right of self-determination, as well as questions of treaty succession and succession in matters of State responsibility with regard to acts committed by the PLO.}, language = {en} } @article{SchindlerWolffKissleretal.2015, author = {Schindler, Sebastian and Wolff, Wanja and Kissler, Johanna M. and Brand, Ralf}, title = {Cerebral correlates of faking}, series = {Frontiers in Behavioral Neuroscience}, volume = {9}, journal = {Frontiers in Behavioral Neuroscience}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1662-5153}, doi = {10.3389/fnbeh.2015.00139}, pages = {1 -- 13}, year = {2015}, abstract = {Direct assessment of attitudes toward socially sensitive topics can be affected by deception attempts. Reaction-time based indirect measures, such as the Implicit Association Test (IAT), are less susceptible to such biases. Neuroscientific evidence shows that deception can evoke characteristic ERP differences. However, the cerebral processes involved in faking an IAT are still unknown. We randomly assigned 20 university students (15 females, 24.65 +/- 3.50 years of age) to a counterbalanced repeated-measurements design, requesting them to complete a Brief-IAT (BIAT) on attitudes toward doping without deception instruction, and with the instruction to fake positive and negative doping attitudes. Cerebral activity during BIAT completion was assessed using high-density EEG. Event-related potentials during faking revealed enhanced frontal and reduced occipital negativity, starting around 150 ms after stimulus presentation. Further, a decrease in the P300 and LPP components was observed. Source analyses showed enhanced activity in the right inferior frontal gyrus between 150 and 200 ms during faking, thought to reflect the suppression of automatic responses. Further, more activity was found for faking in the bilateral middle occipital gyri and the bilateral temporoparietal junction. Results indicate that faking reaction-time based tests alter brain processes from early stages of processing and reveal the cortical sources of the effects. Analyzing the EEG helps to uncover response patterns in indirect attitude tests and broadens our understanding of the neural processes involved in such faking. This knowledge might be useful for uncovering faking in socially sensitive contexts, where attitudes are likely to be concealed.}, language = {en} } @article{TomaszewskaKrahe2015, author = {Tomaszewska, Paulina and Krah{\´e}, Barbara}, title = {Sexual aggression victimization and perpetration among female and male university students in Poland}, series = {Journal of Interpersonal Violence}, volume = {33}, journal = {Journal of Interpersonal Violence}, number = {4}, publisher = {Sage}, address = {Thousand Oaks, Calif.}, doi = {10.1177/0886260515609583}, pages = {571 -- 594}, year = {2015}, abstract = {This study examined the prevalence of victimization and perpetration of sexual aggression since age 15 in a convenience sample of 565 Polish university students (356 females). The prevalence of sexual aggression was investigated for both males and females from the perspectives of both victims and perpetrators in relation to three coercive strategies, three different victim-perpetrator relationships, and four types of sexual acts. We also examined the extent to which alcohol was consumed in the context of sexually aggressive incidents. The overall self-reported victimization rate was 34.3\% for females and 28.4\% for males. The overall perpetration rate was 11.7\% for males and 6.5\% for females. The gender difference was significant only for perpetration. Prevalence rates of both victimization and perpetration were higher for people known to each other than for strangers. In the majority of victimization and perpetration incidents, alcohol was consumed by one or both parties involved. The findings are discussed in relation to the international evidence and the need for tailored risk prevention and reduction programs.}, language = {en} } @article{HoegeleRuffino2015, author = {Hoegele, Michael and Ruffino, Paulo}, title = {Averaging along foliated Levy diffusions}, series = {Nonlinear analysis : theory, methods \& applications ; an international multidisciplinary journal}, volume = {112}, journal = {Nonlinear analysis : theory, methods \& applications ; an international multidisciplinary journal}, publisher = {Elsevier}, address = {Oxford}, issn = {0362-546X}, doi = {10.1016/j.na.2014.09.006}, pages = {1 -- 14}, year = {2015}, abstract = {This article studies the dynamics of the strong solution of a SDE driven by a discontinuous Levy process taking values in a smooth foliated manifold with compact leaves. It is assumed that it is foliated in the sense that its trajectories stay on the leaf of their initial value for all times almost surely. Under a generic ergodicity assumption for each leaf, we determine the effective behaviour of the system subject to a small smooth perturbation of order epsilon > 0, which acts transversal to the leaves. The main result states that, on average, the transversal component of the perturbed SDE converges uniformly to the solution of a deterministic ODE as e tends to zero. This transversal ODE is generated by the average of the perturbing vector field with respect to the invariant measures of the unperturbed system and varies with the transversal height of the leaves. We give upper bounds for the rates of convergence and illustrate these results for the random rotations on the circle. This article complements the results by Gonzales and Ruffino for SDEs of Stratonovich type to general Levy driven SDEs of Marcus type.}, language = {en} } @article{BondueBeier2015, author = {Bond{\"u}, Rebecca and Beier, Sophia}, title = {Two of a Kind? Differences and similarities of attacks in schools and in institutes of higher aducation}, series = {Journal of interpersonal violence : concerned with the study and treatment of victims and perpetrators of physical and sexual violence}, volume = {30}, journal = {Journal of interpersonal violence : concerned with the study and treatment of victims and perpetrators of physical and sexual violence}, number = {2}, publisher = {Sage Publ.}, address = {Thousand Oaks}, issn = {0886-2605}, doi = {10.1177/0886260514533156}, pages = {253 -- 271}, year = {2015}, abstract = {School attacks are attracting increasing attention in aggression research. Recent systematic analyses provided new insights into offense and offender characteristics. Less is known about attacks in institutes of higher education (e.g., universities). It is therefore questionable whether the term "school attack" should be limited to institutions of general education or could be extended to institutions of higher education. Scientific literature is divided in distinguishing or unifying these two groups and reports similarities as well as differences. We researched 232 school attacks and 45 attacks in institutes of higher education throughout the world and conducted systematic comparisons between the two groups. The analyses yielded differences in offender (e.g., age, migration background) and offense characteristics (e.g., weapons, suicide rates), and some similarities (e.g., gender). Most differences can apparently be accounted for by offenders' age and situational influences. We discuss the implications of our findings for future research and the development of preventative measures.}, language = {en} } @article{EscribanoAkhmatskayaReichetal.2015, author = {Escribano, Bruno and Akhmatskaya, Elena and Reich, Sebastian and Azpiroz, Jon M.}, title = {Multiple-time-stepping generalized hybrid Monte Carlo methods}, series = {Journal of computational physics}, volume = {280}, journal = {Journal of computational physics}, publisher = {Elsevier}, address = {San Diego}, issn = {0021-9991}, doi = {10.1016/j.jcp.2014.08.052}, pages = {1 -- 20}, year = {2015}, abstract = {Performance of the generalized shadow hybrid Monte Carlo (GSHMC) method [1], which proved to be superior in sampling efficiency over its predecessors [2-4], molecular dynamics and hybrid Monte Carlo, can be further improved by combining it with multi-time-stepping (MTS) and mollification of slow forces. We demonstrate that the comparatively simple modifications of the method not only lead to better performance of GSHMC itself but also allow for beating the best performed methods, which use the similar force splitting schemes. In addition we show that the same ideas can be successfully applied to the conventional generalized hybrid Monte Carlo method (GHMC). The resulting methods, MTS-GHMC and MTS-GSHMC, provide accurate reproduction of thermodynamic and dynamical properties, exact temperature control during simulation and computational robustness and efficiency. MTS-GHMC uses a generalized momentum update to achieve weak stochastic stabilization to the molecular dynamics (MD) integrator. MTS-GSHMC adds the use of a shadow (modified) Hamiltonian to filter the MD trajectories in the HMC scheme. We introduce a new shadow Hamiltonian formulation adapted to force-splitting methods. The use of such Hamiltonians improves the acceptance rate of trajectories and has a strong impact on the sampling efficiency of the method. Both methods were implemented in the open-source MD package ProtoMol and were tested on a water and a protein systems. Results were compared to those obtained using a Langevin Molly (LM) method [5] on the same systems. The test results demonstrate the superiority of the new methods over LM in terms of stability, accuracy and sampling efficiency. This suggests that putting the MTS approach in the framework of hybrid Monte Carlo and using the natural stochasticity offered by the generalized hybrid Monte Carlo lead to improving stability of MTS and allow for achieving larger step sizes in the simulation of complex systems.}, language = {en} } @article{BlankenburgBalfanzHayashietal.2015, author = {Blankenburg, Stefanie and Balfanz, Sabine and Hayashi, Y. and Shigenobu, S. and Miura, T. and Baumann, Otto and Baumann, Arnd and Blenau, Wolfgang}, title = {Cockroach GABA(B) receptor subtypes: Molecular characterization, pharmacological properties and tissue distribution}, series = {Neuropharmacology}, volume = {88}, journal = {Neuropharmacology}, publisher = {Elsevier}, address = {Oxford}, issn = {0028-3908}, doi = {10.1016/j.neuropharm.2014.08.022}, pages = {134 -- 144}, year = {2015}, abstract = {gamma-aminobutyric acid (GABA) is the predominant inhibitory neurotransmitter in the central nervous system (CNS). Its effects are mediated by either ionotropic GABA(A) receptors or metabotropic GABA(B) receptors. GABA(B) receptors regulate, via Gi/o, G-proteins, ion channels, and adenylyl cyclases. In humans, GABA(B) receptor subtypes are involved in the etiology of neurologic and psychiatric disorders. In arthropods, however, these members of the G-protein-coupled receptor family are only inadequately characterized. Interestingly, physiological data have revealed important functions of GABA(B) receptors in the American cockroach, Periplaneta americana. We have cloned cDNAs coding for putative GABA(B) receptor subtypes 1 and 2 of P. americana (PeaGB1 and PeaGB2). When both receptor proteins are co-expressed in mammalian cells, activation of the receptor heteromer with GABA leads to a dose-dependent decrease in cAMP production. The pharmacological profile differs from that of mammalian and Drosophila GABA(B) receptors. Western blot analyses with polyclonal antibodies have revealed the expression of PeaGB1 and PeaGB2 in the CNS of the American cockroach. In addition to the widespread distribution in the brain, PeaGB1 is expressed in salivary glands and male accessory glands. Notably, PeaGB1-like immunoreactivity has been detected in the GABAergic salivary neuron 2, suggesting that GABA(B) receptors act as autoreceptors in this neuron.}, language = {en} } @article{GhaniOpitzPingeletal.2015, author = {Ghani, Fatemeh and Opitz, Andreas and Pingel, Patrick and Heimel, Georg and Salzmann, Ingo and Frisch, Johannes and Neher, Dieter and Tsami, Argiri and Scherf, Ullrich and Koch, Norbert}, title = {Charge Transfer in and Conductivity of Molecularly Doped Thiophene-Based Copolymers}, series = {Journal of polymer science : B, Polymer physics}, volume = {53}, journal = {Journal of polymer science : B, Polymer physics}, number = {1}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0887-6266}, doi = {10.1002/polb.23631}, pages = {58 -- 63}, year = {2015}, abstract = {The electrical conductivity of organic semiconductors can be enhanced by orders of magnitude via doping with strong molecular electron acceptors or donors. Ground-state integer charge transfer and charge-transfer complex formation between organic semiconductors and molecular dopants have been suggested as the microscopic mechanisms causing these profound changes in electrical materials properties. Here, we study charge-transfer interactions between the common molecular p-dopant 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane and a systematic series of thiophene-based copolymers by a combination of spectroscopic techniques and electrical measurements. Subtle variations in chemical structure are seen to significantly impact the nature of the charge-transfer species and the efficiency of the doping process, underlining the need for a more detailed understanding of the microscopic doping mechanism in organic semiconductors to reliably guide targeted chemical design.}, language = {en} } @article{AhmadShoaibPrinetto2015, author = {Ahmad, Nadeem and Shoaib, Umar and Prinetto, Paolo}, title = {Usability of Online Assistance From Semiliterate Users' Perspective}, series = {International journal of human computer interaction}, volume = {31}, journal = {International journal of human computer interaction}, number = {1}, publisher = {Taylor \& Francis Group}, address = {Philadelphia}, issn = {1044-7318}, doi = {10.1080/10447318.2014.925772}, pages = {55 -- 64}, year = {2015}, language = {en} } @article{CaoHerzschuhNietal.2015, author = {Cao, Xianyong and Herzschuh, Ulrike and Ni, Jian and Zhao, Yan and B{\"o}hmer, Thomas}, title = {Spatial and temporal distributions of major tree taxa in eastern continental Asia during the last 22,000 years}, series = {The Holocene : an interdisciplinary journal focusing on recent environmental change}, volume = {25}, journal = {The Holocene : an interdisciplinary journal focusing on recent environmental change}, number = {1}, publisher = {Sage Publ.}, address = {London}, issn = {0959-6836}, doi = {10.1177/0959683614556385}, pages = {79 -- 91}, year = {2015}, abstract = {This study investigates the spatial and temporal distributions of 14 key arboreal taxa and their driving forces during the last 22,000 calendar years before ad 1950 (kyr BP) using a taxonomically harmonized and temporally standardized fossil pollen dataset with a 500-year resolution from the eastern part of continental Asia. Logistic regression was used to estimate pollen abundance thresholds for vegetation occurrence (presence or dominance), based on modern pollen data and present ranges of 14 taxa in China. Our investigation reveals marked changes in spatial and temporal distributions of the major arboreal taxa. The thermophilous (Castanea, Castanopsis, Cyclobalanopsis, Fagus, Pterocarya) and eurythermal (Juglans, Quercus, Tilia, Ulmus) broadleaved tree taxa were restricted to the current tropical or subtropical areas of China during the Last Glacial Maximum (LGM) and spread northward since c. 14.5kyr BP. Betula and conifer taxa (Abies, Picea, Pinus), in contrast, retained a wider distribution during the LGM and showed no distinct expansion direction during the Late Glacial. Since the late mid-Holocene, the abundance but not the spatial extent of most trees decreased. The changes in spatial and temporal distributions for the 14 taxa are a reflection of climate changes, in particular monsoonal moisture, and, in the late Holocene, human impact. The post-LGM expansion patterns in eastern continental China seem to be different from those reported for Europe and North America, for example, the westward spread for eurythermal broadleaved taxa.}, language = {en} } @article{GhoshCherstvyMetzler2015, author = {Ghosh, Surya K. and Cherstvy, Andrey G. and Metzler, Ralf}, title = {Non-universal tracer diffusion in crowded media of non-inert obstacles}, series = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, volume = {17}, journal = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, number = {3}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/c4cp03599b}, pages = {1847 -- 1858}, year = {2015}, abstract = {We study the diffusion of a tracer particle, which moves in continuum space between a lattice of excluded volume, immobile non-inert obstacles. In particular, we analyse how the strength of the tracer-obstacle interactions and the volume occupancy of the crowders alter the diffusive motion of the tracer. From the details of partitioning of the tracer diffusion modes between trapping states when bound to obstacles and bulk diffusion, we examine the degree of localisation of the tracer in the lattice of crowders. We study the properties of the tracer diffusion in terms of the ensemble and time averaged mean squared displacements, the trapping time distributions, the amplitude variation of the time averaged mean squared displacements, and the non-Gaussianity parameter of the diffusing tracer. We conclude that tracer-obstacle adsorption and binding triggers a transient anomalous diffusion. From a very narrow spread of recorded individual time averaged trajectories we exclude continuous type random walk processes as the underlying physical model of the tracer diffusion in our system. For moderate tracer-crowder attraction the motion is found to be fully ergodic, while at stronger attraction strength a transient disparity between ensemble and time averaged mean squared displacements occurs. We also put our results into perspective with findings from experimental single-particle tracking and simulations of the diffusion of tagged tracers in dense crowded suspensions. Our results have implications for the diffusion, transport, and spreading of chemical components in highly crowded environments inside living cells and other structured liquids.}, language = {en} } @article{MorgnerLecointreCharbonniereetal.2015, author = {Morgner, Frank and Lecointre, Alexandre and Charbonniere, Loic J. and L{\"o}hmannsr{\"o}ben, Hans-Gerd}, title = {Detecting free hemoglobin in blood plasma and serum with luminescent terbium complexes}, series = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, volume = {17}, journal = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, number = {3}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/c4cp04206a}, pages = {1740 -- 1745}, year = {2015}, abstract = {Hemolysis, the rupturing of red blood cells, can result from numerous medical conditions (in vivo) or occur after collecting blood specimen or extracting plasma and serum out of whole blood (in vitro). In clinical laboratory practice, hemolysis can be a serious problem due to its potential to bias detection of various analytes or biomarkers. Here we present the first "mix-and-measure' method to assess the degree of hemolysis in biosamples using luminescence spectroscopy. Luminescent terbium complexes (LTC) were studied in the presence of free hemoglobin (Hb) as indicators for hemolysis in TRIS-buffer, and in fresh human plasma with absorption, excitation and emission measurements. Our findings indicate dynamic as well as resonance energy transfer (FRET) between the LTC and the porphyrin ligand of hemoglobin. This transfer leads to a decrease in luminescence intensity and decay time even at nanomolar hemoglobin concentrations either in buffer or plasma. Luminescent terbium complexes are very sensitive to free hemoglobin in buffer and blood plasma. Due to the instant change in luminescence properties of the LTC in presence of Hb it is possible to access the concentration of hemoglobin via spectroscopic methods without incubation time or further treatment of the sample thus enabling a rapid and sensitive detection of hemolysis in clinical diagnostics.}, language = {en} }