@phdthesis{Kuehn2010, author = {K{\"u}hn, Nicolas M.}, title = {Empirical ground-motion models for probabilistic seismic hazard analysis : a graphical model perspective}, address = {Potsdam}, pages = {125 S.}, year = {2010}, language = {en} } @phdthesis{Eckstein2010, author = {Eckstein, Lars}, title = {The Culture of Lyrics}, isbn = {978-3-868212-259-4}, year = {2010}, language = {en} } @phdthesis{Nikiforova2010, author = {Nikiforova, Victoria}, title = {Processing of metabolic information through biological networks}, address = {Potsdam}, pages = {157 S.}, year = {2010}, language = {en} } @phdthesis{Eckstein2010, author = {Eckstein, Lars}, title = {Reading song lyrics}, series = {Internationale Forschungen zur Allgemeinen und Vergleichenden Literaturwissenschaft}, volume = {137}, journal = {Internationale Forschungen zur Allgemeinen und Vergleichenden Literaturwissenschaft}, publisher = {Rodopi}, address = {Amsterdam}, isbn = {978-90-420-3035-0}, pages = {291 S.}, year = {2010}, language = {en} } @phdthesis{Maitrejean2010, author = {Maitrejean, Marie}, title = {Proteostasis of the tonoplast : synthesis, sorting and turnover of the potassum channel AtTPK1}, address = {Potsdam}, pages = {152 S.}, year = {2010}, language = {en} } @phdthesis{Cheng2010, author = {Cheng, Feng}, title = {Physical separation technology and its lock-keeper implementation}, address = {Potsdam}, pages = {114 S.}, year = {2010}, language = {en} } @phdthesis{Knorr2010, author = {Knorr, Roland L.}, title = {Giant vesicles - influence of phase state, composition and electric pulses}, address = {Potsdam}, pages = {86 S.}, year = {2010}, language = {en} } @phdthesis{Bleiholder2010, author = {Bleiholder, Jens}, title = {Data fusion and conflict resolution in integrated information systems}, address = {Potsdam}, pages = {171 S.}, year = {2010}, language = {en} } @phdthesis{Pornsawad2010, author = {Pornsawad, Pornsarp}, title = {Solution of nonlinear inverse ill-posed problems via Runge-Kutta methods}, address = {Potsdam}, pages = {104 S.}, year = {2010}, language = {en} } @phdthesis{Gerber2010, author = {Gerber, Chimgee Baasanjav}, title = {Detection and identification of genotoxicant from brassica plants}, address = {Potsdam}, pages = {191 S.}, year = {2010}, language = {en} } @phdthesis{Uflacker2010, author = {Uflacker, Matthias}, title = {Monitoring virtual team collaboration : methods, applications and experiences in engineering design}, address = {Potsdam}, pages = {203 S.}, year = {2010}, language = {en} } @phdthesis{Cui2010, author = {Cui, Jing}, title = {Preparation of medical grade, amorphous polymer systems with adjustable stiffness and development of self- surfficiently moving model scaffolds based on shape-memory polymer composites}, address = {Potsdam}, year = {2010}, language = {en} } @phdthesis{Badura2010, author = {Badura, Benjamin}, title = {Dezentralization, network governance and territorial competitiveness : theory with empirical evidence from local governments in El Salvador and Nicaragua}, address = {Potsdam}, pages = {246 S.}, year = {2010}, language = {en} } @phdthesis{Ganzert2010, author = {Ganzert, Lars}, title = {Bacterial diverity and adaption in permafrost-affected soils of maritime Antartica and Northeast Greenland}, address = {Potsdam}, pages = {104 S.}, year = {2010}, language = {en} } @phdthesis{Chanana2010, author = {Chanana, Munish}, title = {Synthesis of stimuli-responsive and switchable inorganic nanoparticles for biomedical applications}, address = {Potsdam}, pages = {128, E-1 S. : Ill., graph. Darst.}, year = {2010}, language = {en} } @phdthesis{Bohnet2010, author = {Bohnet, Johannes}, title = {Visualization of Execution Traces and its Application to Software Maintenance}, address = {Potsdam}, pages = {150 S.}, year = {2010}, language = {en} } @phdthesis{Hoff2010, author = {Hoff, Ulrike}, title = {Freshwater diatoms as indicators for Holocene environmental- and climate changes on Kamachatka, Russia}, address = {Potsdam}, pages = {VII, 95, XXXVIII S.}, year = {2010}, language = {en} } @phdthesis{Klasczyk2010, author = {Klasczyk, Benjamin}, title = {Interactions of ions with membranes}, address = {Potsdam}, pages = {116 S.}, year = {2010}, language = {en} } @phdthesis{Santos2010, author = {Santos, Francisca dos}, title = {Towards a mechanistic understanding of species and community responses to climate change : the role of disturbances interaction}, address = {Potsdam}, pages = {89 S.}, year = {2010}, language = {en} } @phdthesis{Christian2010, author = {Christian, Nils}, title = {Genome-scale metabolic networks: Quality improvement and habitat interaction analysis}, address = {Potsdam}, pages = {135 S.}, year = {2010}, language = {en} } @phdthesis{Schwarte2010, author = {Schwarte, Sandra}, title = {Genetic variation of photosynthesis and starch metabolism genes in Arabidopsis thaliana}, address = {Potsdam}, year = {2010}, language = {en} } @phdthesis{Plenkers2010, author = {Plenkers, Katrin}, title = {On the Characteristics of Mining-Induced Seismicity with Magnitudes -57 every year, being more than 15\% of the events worldwide. Earthquakes with magnitude above 9 happen far more infrequently, but with catastrophic effects. The most severe consequences thereby arise from tsunamis triggered by these subduction-related earthquakes, as the Sumatra-Andaman event in 2004 showed. In order to enable efficient tsunami early warning, which includes the estimation of wave heights and arrival times, it is necessary to combine different types of real-time sensor data with numerical models of earthquake sources and tsunami propagation. This thesis was created as a result of the GITEWS project (German Indonesian Tsunami Early Warning System). It is based on five research papers and manuscripts. Main project-related task was the development of a database containing realistic earthquake scenarios for the Sunda Arc. This database provides initial conditions for tsunami propagation modeling used by the simulation system at the early warning center. An accurate discretization of the subduction geometry, consisting of 25x150 subfaults was constructed based on seismic data. Green's functions, representing the deformational response to unit dip- and strike slip at the subfaults, were computed using a layered half-space approach. Different scaling relations for earthquake dimensions and slip distribution were implemented. Another project-related task was the further development of the 'GPS-shield' concept. It consists of a constellation of near field GPS-receivers, which are shown to be very valuable for tsunami early warning. The major part of this thesis is related to the geophysical interpretation of GPS data. Coseismic surface displacements caused by the 2004 Sumatra earthquake are inverted for slip at the fault. The effect of different Earth layer models is tested, favoring continental structure. The possibility of splay faulting is considered and shown to be a secondary order effect in respect to tsunamigenity for this event. Tsunami models based on source inversions are compared to satellite radar altimetry observations. Postseismic GPS time series are used to test a wide parameter range of uni- and biviscous rheological models of the asthenosphere. Steady-state Maxwell rheology is shown to be incompatible with near-field GPS data, unless large afterslip, amounting to more than 10\% of the coseismic moment is assumed. In contrast, transient Burgers rheology is in agreement with data without the need for large aseismic afterslip. Comparison to postseismic geoid observation by the GRACE satellites reveals that even with afterslip, the model implementing Maxwell rheology results in amplitudes being too small, and thus supports a biviscous asthenosphere. A simple approach based on the assumption of quasi-static deformation propagation is introduced and proposed for inversion of coseismic near-field GPS time series. Application of this approach to observations from the 2004 Sumatra event fails to quantitatively reconstruct the rupture propagation, since a priori conditions are not fulfilled in this case. However, synthetic tests reveal the feasibility of such an approach for fast estimation of rupturing properties.}, language = {en} } @phdthesis{Pilz2010, author = {Pilz, Marco}, title = {A comparison of proxies for seismic site conditions and amplification for the large urban area of Santiago de Chile}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-52961}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Situated in an active tectonic region, Santiago de Chile, the country´s capital with more than six million inhabitants, faces tremendous earthquake hazard. Macroseismic data for the 1985 Valparaiso and the 2010 Maule events show large variations in the distribution of damage to buildings within short distances indicating strong influence of local sediments and the shape of the sediment-bedrock interface on ground motion. Therefore, a temporary seismic network was installed in the urban area for recording earthquake activity, and a study was carried out aiming to estimate site amplification derived from earthquake data and ambient noise. The analysis of earthquake data shows significant dependence on the local geological structure with regards to amplitude and duration. Moreover, the analysis of noise spectral ratios shows that they can provide a lower bound in amplitude for site amplification and, since no variability in terms of time and amplitude is observed, that it is possible to map the fundamental resonance frequency of the soil for a 26 km x 12 km area in the northern part of the Santiago de Chile basin. By inverting the noise spectral rations, local shear wave velocity profiles could be derived under the constraint of the thickness of the sedimentary cover which had previously been determined by gravimetric measurements. The resulting 3D model was derived by interpolation between the single shear wave velocity profiles and shows locally good agreement with the few existing velocity profile data, but allows the entire area, as well as deeper parts of the basin, to be represented in greater detail. The wealth of available data allowed further to check if any correlation between the shear wave velocity in the uppermost 30 m (vs30) and the slope of topography, a new technique recently proposed by Wald and Allen (2007), exists on a local scale. While one lithology might provide a greater scatter in the velocity values for the investigated area, almost no correlation between topographic gradient and calculated vs30 exists, whereas a better link is found between vs30 and the local geology. When comparing the vs30 distribution with the MSK intensities for the 1985 Valparaiso event it becomes clear that high intensities are found where the expected vs30 values are low and over a thick sedimentary cover. Although this evidence cannot be generalized for all possible earthquakes, it indicates the influence of site effects modifying the ground motion when earthquakes occur well outside of the Santiago basin. Using the attained knowledge on the basin characteristics, simulations of strong ground motion within the Santiago Metropolitan area were carried out by means of the spectral element technique. The simulation of a regional event, which has also been recorded by a dense network installed in the city of Santiago for recording aftershock activity following the 27 February 2010 Maule earthquake, shows that the model is capable to realistically calculate ground motion in terms of amplitude, duration, and frequency and, moreover, that the surface topography and the shape of the sediment bedrock interface strongly modify ground motion in the Santiago basin. An examination on the dependency of ground motion on the hypocenter location for a hypothetical event occurring along the active San Ram{\´o}n fault, which is crossing the eastern outskirts of the city, shows that the unfavorable interaction between fault rupture, radiation mechanism, and complex geological conditions in the near-field may give rise to large values of peak ground velocity and therefore considerably increase the level of seismic risk for Santiago de Chile.}, language = {en} } @phdthesis{Borchers2010, author = {Borchers, Andreas}, title = {Glaciomarine sedimentation at the continental margin of Prydz Bay, East Antarctica : implications on palaeoenvironmental changes during the Quaternary}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-52620}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {The Antarctic plays an important role in the global climate system. On the one hand, the Antarctic Ice Sheet is the largest freshwater reservoir on Earth. On the other hand, a major proportion of the global bottom-water formation takes place in Antarctic shelf regions, forcing the global thermohaline circulation. The main goal of this dissertation is to provide new insights into the dynamics and stability of the EAIS during the Quaternary. Additionally, variations in the activity of bottom-water formation and their causes are investigated. The dissertation is a German contribution to the International Polar Year 2007/ 2008 and was funded by the 'Deutsche Forschungsgesellschaft' (DFG) within the scope of priority program 1158 'Antarctic research with comparative studies in Arctic ice regions'. During RV Polarstern expedition ANT-XXIII/9, glaciomarine sediments were recovered from the Prydz Bay-Kerguelen region. Prydz Bay is a key region for the study of East EAIS dynamics, as 16\% of the EAIS are drained through the Lambert Glacier into the bay. Thereby, the glacier transports sediment into Prydz Bay which is then further distributed by calving icebergs or by current transport. The scientific approach of this dissertation is the reconstruction of past glaciomarine environments to infer on the response of the Lambert Glacier-Amery Ice Shelf system to climate shifts during the Quaternary. To characterize the depositional setting, sedimentological methods are used and statistical analyses are applied. Mineralogical and (bio)geochemical methods provide a means to reconstruct sediment provenances and to provide evidence on changes in the primary production in the surface water column. Age-depth models were constructed based on palaeomagnetic and palaeointensity measurements, diatom stratigraphy and radiocarbon dating. Sea-bed surface sediments in the investigation area show distinct variations in terms of their clay minerals and heavy-mineral assemblages. Considerable differences in the mineralogical composition of surface sediments are determined on the continental shelf. Clay minerals as well as heavy minerals provide useful parameters to differentiate between sediments which originated from erosion of crystalline rocks and sediments originating from Permo-Triassic deposits. Consequently, mineralogical parameters can be used to reconstruct the provenance of current-transported and ice-rafted material. The investigated sediment cores cover the time intervals of the last 1.4 Ma (continental slope) and the last 12.8 cal. ka BP (MacRobertson shelf). The sediment deposits were mainly influenced by glacial and oceanographic processes and further by biological activity (continental shelf), meltwater input and possibly gravitational transport. Sediments from the continental slope document two major deglacial events: the first deglaciation is associated with the mid-Pleistocene warming recognized around the Antarctic. In Prydz Bay, the Lambert Glacier-Amery Ice Shelf retreated far to the south and high biogenic productivity commenced or biogenic remains were better preserved due to increased sedimentation rates. Thereafter, stable glacial conditions continued until 400 - 500 ka BP. Calving of icebergs was restricted to the western part of the Lambert Glacier. The deeper bathymetry in this area allows for floating ice shelf even during times of decreased sea-level. Between 400 - 500 ka BP and the last interglacial (marine isotope stage 5) the glacier was more dynamic. During or shortly after the last interglacial the LAIS retreated again due to sea-level rise of 6 - 9 m. Both deglacial events correlate with a reduction in the thickness of ice masses in the Prince Charles Mountains. It indicates that a disintegration of the Amery Ice Shelf possibly led to increased drainage of ice masses from the Prydz Bay hinterland. A new end-member modelling algorithm was successfully applied on sediments from the MacRobertson shelf used to unmix the sand grain size fractions sorted by current activity and ice transport, respectively. Ice retreat on MacRobertson Shelf commenced 12.8 cal. ka BP and ended around 5.5 cal. ka BP. During the Holocene, strong fluctuations of the bottomwater activity were observed, probably related to variations of sea-ice formation in the Cape Darnley polynya. Increased activity of bottom-water flow was reconstructed at transitions from warm to cool conditions, whereas bottom-water activity receded during the mid- Holocene climate optimum. It can be concluded that the Lambert Glacier-Amery Ice Shelf system was relatively stable in terms of climate variations during the Quaternary. In contrast, bottom-water formation due to polynya activity was very sensitive to changes in atmospheric forcing and should gain more attention in future research.}, language = {en} } @phdthesis{Zaupa2010, author = {Zaupa, Alessandro}, title = {Physical crosslinking of gelatin : a supramolecular approach to biomaterials}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-52888}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {This work describes the realization of physically crosslinked networks based on gelatin by the introduction of functional groups enabling specific supramolecular interactions. Molecular models were developed in order to predict the material properties and permit to establish a knowledge-based approach to material design. The effect of additional supramolecular interactions with hydroxyapaptite was then studied in composite materials. The calculated properties are compared to experimental results to validate the models. The models are then further used for the study of physically crosslinked networks. Gelatin was functionalized with desaminotyrosine (DAT) and desaminotyrosyl-tyrosine (DATT) side groups, derived from the natural amino acid tyrosine. These group can potentially undergo to π-π and hydrogen bonding interactions also under physiological conditions. Molecular dynamics (MD) simulations were performed on models with 0.8 wt.-\% or 25 wt.-\% water content, using the second generation forcefield CFF91. The validation of the models was obtained by the comparison with specific experimental data such as, density, peptide conformational angles and X-ray scattering spectra. The models were then used to predict the supramolecular organization of the polymer chain, analyze the formation of physical netpoints and calculate the mechanical properties. An important finding of simulation was that with the increase of aromatic groups also the number of observed physical netpoints increased. The number of relatively stable physical netpoints, on average zero 0 for natural gelatin, increased to 1 and 6 for DAT and DATT functionalized gelatins respectively. A comparison with the Flory-Rehner model suggested reduced equilibrium swelling by factor 6 of the DATT-functionalized materials in water. The functionalized gelatins could be synthesized by chemoselective coupling of the free carboxylic acid groups of DAT and DATT to the free amino groups of gelatin. At 25 wt.-\% water content, the simulated and experimentally determined elastic mechanical properties (e.g. Young Modulus) were both in the order of GPa and were not influenced by the degree of aromatic modification. The experimental equilibrium degree of swelling in water decreased with increasing the number of inserted aromatic functions (from 2800 vol.-\% for pure gelatin to 300 vol.-\% for the DATT modified gelatin), at the same time, Young's modulus, elongation at break, and maximum tensile strength increased. It could be show that the functionalization with DAT and DATT influences the chain organization of gelatin based materials together with a controlled drying condition. Functionalization with DAT and DATT lead to a drastic reduction of helical renaturation, that could be more finely controlled by the applied drying conditions. The properties of the materials could then be influenced by application of two independent methods. Composite materials of DAT and DATT functionalized gelatins with hydroxyapatite (HAp) show a drastic reduction of swelling degree. In tensile tests and rheological measurements, the composites equilibrated in water had increased Young's moduli (from 200 kPa up to 2 MPa) and tensile strength (from 57 kPa up to 1.1 MPa) compared to the natural polymer matrix without affecting the elongation at break. Furthermore, an increased thermal stability from 40 °C to 85 °C of the networks could be demonstrated. The differences of the behaviour of the functionalized gelatins to pure gelatin as matrix suggested an additional stabilizing bond between the incorporated aromatic groups to the hydroxyapatite.}, language = {en} } @phdthesis{Poltrock2010, author = {Poltrock, Silvana}, title = {About the relation between implicit Theory of Mind \& the comprehension of complement sentences}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-52293}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Previous studies on the relation between language and social cognition have shown that children's mastery of embedded sentential complements plays a causal role for the development of a Theory of Mind (ToM). Children start to succeed on complementation tasks in which they are required to report the content of an embedded clause in the second half of the fourth year. Traditional ToM tasks test the child's ability to predict that a person who is holding a false belief (FB) about a situation will act "falsely". In these task, children do not represent FBs until the age of 4 years. According the linguistic determinism hypothesis, only the unique syntax of complement sentences provides the format for representing FBs. However, experiments measuring children's looking behavior instead of their explicit predictions provided evidence that already 2-year olds possess an implicit ToM. This dissertation examined the question of whether there is an interrelation also between implicit ToM and the comprehension of complement sentences in typically developing German preschoolers. Two studies were conducted. In a correlational study (Study 1 ), 3-year-old children's performance on a traditional (explicit) FB task, on an implicit FB task and on language tasks measuring children's comprehension of tensed sentential complements were collected and tested for their interdependence. Eye-tracking methodology was used to assess implicit ToM by measuring participants' spontaneous anticipatory eye movements while they were watching FB movies. Two central findings emerged. First, predictive looking (implicit ToM) was not correlated with complement mastery, although both measures were associated with explicit FB task performance. This pattern of results suggests that explicit, but not implicit ToM is language dependent. Second, as a group, 3-year-olds did not display implicit FB understanding. That is, previous findings on a precocious reasoning ability could not be replicated. This indicates that the characteristics of predictive looking tasks play a role for the elicitation of implicit FB understanding as the current task was completely nonverbal and as complex as traditional FB tasks. Study 2 took a methodological approach by investigating whether children display an earlier comprehension of sentential complements when using the same means of measurement as used in experimental tasks tapping implicit ToM, namely anticipatory looking. Two experiments were conducted. 3-year-olds were confronted either with a complement sentence expressing the protagonist's FB (Exp. 1) or with a complex sentence expressing the protagonist's belief without giving any information about the truth/ falsity of the belief (Exp. 2). Afterwards, their expectations about the protagonist's future behavior were measured. Overall, implicit measures reveal no considerably earlier understanding of sentential complementation. Whereas 3-year-olds did not display a comprehension of complex sentences if these embedded a false proposition, children from 3;9 years on were proficient in processing complement sentences if the truth value of the embedded proposition could not be evaluated. This pattern of results suggests that (1) the linguistic expression of a person's FB does not elicit implicit FB understanding and that (2) the assessment of the purely syntactic understanding of complement sentences is affected by competing reality information. In conclusion, this dissertation found no evidence that the implicit ToM is related to the comprehension of sentential complementation. The findings suggest that implicit ToM might be based on nonlinguistic processes. Results are discussed in the light of recently proposed dual-process models that assume two cognitive mechanisms that account for different levels of ToM task performance.}, language = {en} } @phdthesis{Kirchner2010, author = {Kirchner, Henriette}, title = {The ghrelin system links dietary lipids with the endocrine control of energy homeostasis}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-52393}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Ghrelin is a unique hunger-inducing stomach-borne hormone. It activates orexigenic circuits in the central nervous system (CNS) when acylated with a fatty acid residue by the Ghrelin O-acyltransferase (GOAT). Soon after the discovery of ghrelin a theoretical model emerged which suggests that the gastric peptide ghrelin is the first "meal initiation molecule}, language = {en} } @phdthesis{Arvidsson2010, author = {Arvidsson, Samuel Janne}, title = {Identification of growth-related tonoplast proteins in Arabidopsis thaliana}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-52408}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {In a very simplified view, the plant leaf growth can be reduced to two processes, cell division and cell expansion, accompanied by expansion of their surrounding cell walls. The vacuole, as being the largest compartment of the plant cell, plays a major role in controlling the water balance of the plant. This is achieved by regulating the osmotic pressure, through import and export of solutes over the vacuolar membrane (the tonoplast) and by controlling the water channels, the aquaporins. Together with the control of cell wall relaxation, vacuolar osmotic pressure regulation is thought to play an important role in cell expansion, directly by providing cell volume and indirectly by providing ion and pH homestasis for the cytosoplasm. In this thesis the role of tonoplast protein coding genes in cell expansion in the model plant Arabidopsis thaliana is studied and genes which play a putative role in growth are identified. Since there is, to date, no clearly identified protein localization signal for the tonoplast, there is no possibility to perform genome-wide prediction of proteins localized to this compartment. Thus, a series of recent proteomic studies of the tonoplast were used to compile a list of cross-membrane tonoplast protein coding genes (117 genes), and other growth-related genes from notably the growth regulating factor (GRF) and expansin families were included (26 genes). For these genes a platform for high-throughput reverse transcription quantitative real time polymerase chain reaction (RT-qPCR) was developed by selecting specific primer pairs. To this end, a software tool (called QuantPrime, see http://www.quantprime.de) was developed that automatically designs such primers and tests their specificity in silico against whole transcriptomes and genomes, to avoid cross-hybridizations causing unspecific amplification. The RT-qPCR platform was used in an expression study in order to identify candidate growth related genes. Here, a growth-associative spatio-temporal leaf sampling strategy was used, targeting growing regions at high expansion developmental stages and comparing them to samples taken from non-expanding regions or stages of low expansion. Candidate growth related genes were identified after applying a template-based scoring analysis on the expression data, ranking the genes according to their association with leaf expansion. To analyze the functional involvement of these genes in leaf growth on a macroscopic scale, knockout mutants of the candidate growth related genes were screened for growth phenotypes. To this end, a system for non-invasive automated leaf growth phenotyping was established, based on a commercially available image capture and analysis system. A software package was developed for detailed developmental stage annotation of the images captured with the system, and an analysis pipeline was constructed for automated data pre-processing and statistical testing, including modeling and graph generation, for various growth-related phenotypes. Using this system, 24 knockout mutant lines were analyzed, and significant growth phenotypes were found for five different genes.}, language = {en} } @phdthesis{Wegerich2010, author = {Wegerich, Franziska}, title = {Engineered human cytochrome c : investigation of superoxide and protein-protein interaction and application in bioelectronic systems}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50782}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {The aim of this thesis is the design, expression and purification of human cytochrome c mutants and their characterization with regard to electrochemical and structural properties as well as with respect to the reaction with the superoxide radical and the selected proteins sulfite oxidase from human and fungi bilirubin oxidase. All three interaction partners are studied here for the first time with human cyt c and with mutant forms of cyt c. A further aim is the incorporation of the different cyt c forms in two bioelectronic systems: an electrochemical superoxide biosensor with an enhanced sensitivity and a protein multilayer assembly with and without bilirubin oxidase on electrodes. The first part of the thesis is dedicated to the design, expression and characterization of the mutants. A focus is here the electrochemical characterization of the protein in solution and immobilized on electrodes. Further the reaction of these mutants with superoxide was investigated and the possible reaction mechanisms are discussed. In the second part of the work an amperometric superoxide biosensor with selected human cytochrome c mutants was constructed and the performance of the sensor electrodes was studied. The human wild-type and four of the five mutant electrodes could be applied successfully for the detection of the superoxide radical. In the third part of the thesis the reaction of horse heart cyt c, the human wild-type and seven human cyt c mutants with the two proteins sulfite oxidase and bilirubin oxidase was studied electrochemically and the influence of the mutations on the electron transfer reactions was discussed. Finally protein multilayer electrodes with different cyt form including the mutant forms G77K and N70K which exhibit different reaction rates towards BOD were investigated and BOD together with the wild-type and engineered cyt c was embedded in the multilayer assembly. The relevant electron transfer steps and the kinetic behavior of the multilayer electrodes are investigated since the functionality of electroactive multilayer assemblies with incorporated redox proteins is often limited by the electron transfer abilities of the proteins within the multilayer. The formation via the layer-by-layer technique and the kinetic behavior of the mono and bi-protein multilayer system are studied by SPR and cyclic voltammetry. In conclusion this thesis shows that protein engineering is a helpful instrument to study protein reactions as well as electron transfer mechanisms of complex bioelectronic systems (such as bi-protein multilayers). Furthermore, the possibility to design tailored recognition elements for the construction of biosensors with an improved performance is demonstrated.}, language = {en} } @phdthesis{Goetze2010, author = {G{\"o}tze, Jan Philipp}, title = {Influence of protein and solvent environments on quantum chemical properties of photosynthesis enzymes and photoreceptors}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-51135}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {This thesis contains quantum chemical models and force field calculations for the RuBisCO isotope effect, the spectral characteristics of the blue-light sensor BLUF and the light harvesting complex II. The work focuses on the influence of the environment on the corresponding systems. For RuBisCO, it was found that the isotopic effect is almost unaffected by the environment. In case of the BLUF domain, an amino acid was found to be important for the UV/vis spectrum, but unaccounted for in experiments so far (Ser41). The residue was shown to be highly mobile and with a systematic influence on the spectral shift of the BLUF domain chromophore (flavin). Finally, for LHCII it was found that small changes in the geometry of a Chlorophyll b/Violaxanthin chromophore pair can have strong influences regarding the light harvesting mechanism. Especially here it was seen that the proper description of the environment can be critical. In conclusion, the environment was observed to be of often unexpected importance for the molecular properties, and it seems not possible to give a reliable estimate on the changes created by the presence of the environment.}, language = {en} } @phdthesis{Blum2010, author = {Blum, Niklas}, title = {Formalization of a converged internet and telecommunications service environment}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-51146}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {The programmable network envisioned in the 1990s within standardization and research for the Intelligent Network is currently coming into reality using IPbased Next Generation Networks (NGN) and applying Service-Oriented Architecture (SOA) principles for service creation, execution, and hosting. SOA is the foundation for both next-generation telecommunications and middleware architectures, which are rapidly converging on top of commodity transport services. Services such as triple/quadruple play, multimedia messaging, and presence are enabled by the emerging service-oriented IPMultimedia Subsystem (IMS), and allow telecommunications service providers to maintain, if not improve, their position in the marketplace. SOA becomes the de facto standard in next-generation middleware systems as the system model of choice to interconnect service consumers and providers within and between enterprises. We leverage previous research activities in overlay networking technologies along with recent advances in network abstraction, service exposure, and service creation to develop a paradigm for a service environment providing converged Internet and Telecommunications services that we call Service Broker. Such a Service Broker provides mechanisms to combine and mediate between different service paradigms from the two domains Internet/WWW and telecommunications. Furthermore, it enables the composition of services across these domains and is capable of defining and applying temporal constraints during creation and execution time. By adding network-awareness into the service fabric, such a Service Broker may also act as a next generation network-to-service element allowing the composition of crossdomain and cross-layer network and service resources. The contribution of this research is threefold: first, we analyze and classify principles and technologies from Information Technologies (IT) and telecommunications to identify and discuss issues allowing cross-domain composition in a converging service layer. Second, we discuss service composition methods allowing the creation of converged services on an abstract level; in particular, we present a formalized method for model-checking of such compositions. Finally, we propose a Service Broker architecture converging Internet and Telecom services. This environment enables cross-domain feature interaction in services through formalized obligation policies acting as constraints during service discovery, creation, and execution time.}, language = {en} } @phdthesis{Shirzaei2010, author = {Shirzaei, Manoochehr}, title = {Crustal deformation source monitoring using advanced InSAR time series and time dependent inverse modeling}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50774}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Crustal deformation can be the result of volcanic and tectonic activity such as fault dislocation and magma intrusion. The crustal deformation may precede and/or succeed the earthquake occurrence and eruption. Mitigating the associated hazard, continuous monitoring of the crustal deformation accordingly has become an important task for geo-observatories and fast response systems. Due to highly non-linear behavior of the crustal deformation fields in time and space, which are not always measurable using conventional geodetic methods (e.g., Leveling), innovative techniques of monitoring and analysis are required. In this thesis I describe novel methods to improve the ability for precise and accurate mapping the spatiotemporal surface deformation field using multi acquisitions of satellite radar data. Furthermore, to better understand the source of such spatiotemporal deformation fields, I present novel static and time dependent model inversion approaches. Almost any interferograms include areas where the signal decorrelates and is distorted by atmospheric delay. In this thesis I detail new analysis methods to reduce the limitations of conventional InSAR, by combining the benefits of advanced InSAR methods such as the permanent scatterer InSAR (PSI) and the small baseline subsets (SBAS) with a wavelet based data filtering scheme. This novel InSAR time series methodology is applied, for instance, to monitor the non-linear deformation processes at Hawaii Island. The radar phase change at Hawaii is found to be due to intrusions, eruptions, earthquakes and flank movement processes and superimposed by significant environmental artifacts (e.g., atmospheric). The deformation field, I obtained using the new InSAR analysis method, is in good agreement with continuous GPS data. This provides an accurate spatiotemporal deformation field at Hawaii, which allows time dependent source modeling. Conventional source modeling methods usually deal with static deformation field, while retrieving the dynamics of the source requires more sophisticated time dependent optimization approaches. This problem I address by combining Monte Carlo based optimization approaches with a Kalman Filter, which provides the model parameters of the deformation source consistent in time. I found there are numerous deformation sources at Hawaii Island which are spatiotemporally interacting, such as volcano inflation is associated to changes in the rifting behavior, and temporally linked to silent earthquakes. I applied these new methods to other tectonic and volcanic terrains, most of which revealing the importance of associated or coupled deformation sources. The findings are 1) the relation between deep and shallow hydrothermal and magmatic sources underneath the Campi Flegrei volcano, 2) gravity-driven deformation at Damavand volcano, 3) fault interaction associated with the 2010 Haiti earthquake, 4) independent block wise flank motion at the Hilina Fault system, Kilauea, and 5) interaction between salt diapir and the 2005 Qeshm earthquake in southern Iran. This thesis, written in cumulative form including 9 manuscripts published or under review in peer reviewed journals, improves the techniques for InSAR time series analysis and source modeling and shows the mutual dependence between adjacent deformation sources. These findings allow more realistic estimation of the hazard associated with complex volcanic and tectonic systems.}, language = {en} } @phdthesis{DiGiacomo2010, author = {Di Giacomo, Domenico}, title = {Determination of the energy magnitude ME : application to rapid response purposes and insights to regional/local variabilities}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50768}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Recent large earthquakes put in evidence the need of improving and developing robust and rapid procedures to properly calculate the magnitude of an earthquake in a short time after its occurrence. The most famous example is the 26 December 2004 Sumatra earthquake, when the limitations of the standard procedures adopted at that time by many agencies failed to provide accurate magnitude estimates of this exceptional event in time to launch early enough warnings and appropriate response. Being related to the radiated seismic energy ES, the energy magnitude ME is a good estimator of the high frequency content radiated by the source which goes into the seismic waves. However, a procedure to rapidly determine ME (that is to say, within 15 minutes after the earthquake occurrence) was required. Here it is presented a procedure able to provide in a rapid way the energy magnitude ME for shallow earthquakes by analyzing teleseismic P‑waves in the distance range 20-98. To account for the energy loss experienced by the seismic waves from the source to the receivers, spectral amplitude decay functions obtained from numerical simulations of Greens functions based on the average global model AK135Q are used. The proposed method has been tested using a large global dataset (~1000 earthquakes) and the obtained rapid ME estimations have been compared to other magnitude scales from different agencies. Special emphasis is given to the comparison with the moment magnitude MW, since the latter is very popular and extensively used in common seismological practice. However, it is shown that MW alone provide only limited information about the seismic source properties, and that disaster management organizations would benefit from a combined use of MW and ME in the prompt evaluation of an earthquake's tsunami and shaking potential. In addition, since the proposed approach for ME is intended to work without knowledge of the fault plane geometry (often available only hours after an earthquake occurrence), the suitability of this method is discussed by grouping the analyzed earthquakes according to their type of mechanism (strike-slip, normal faulting, thrust faulting, etc.). No clear trend is found from the rapid ME estimates with the different fault plane solution groups. This is not the case for the ME routinely determined by the U.S. Geological Survey, which uses specific radiation pattern corrections. Further studies are needed to verify the effect of such corrections on ME estimates. Finally, exploiting the redundancy of the information provided by the analyzed dataset, the components of variance on the single station ME estimates are investigated. The largest component of variance is due to the intra-station (record-to-record) error, although the inter-station (station-to-station) error is not negligible and is of several magnitude units for some stations. Moreover, it is shown that the intra-station component of error is not random but depends on the travel path from a source area to a given station. Consequently, empirical corrections may be used to account for the heterogeneities of the real Earth not considered in the theoretical calculations of the spectral amplitude decay functions used to correct the recorded data for the propagation effects.}, language = {en} } @phdthesis{Landgraf2010, author = {Landgraf, Angela}, title = {Fault interaction at different time- and length scales : the North Tehran thrust and Mosha-Fasham fault (Alborz mountains, Iran)}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50800}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {The seismically active Alborz mountains of northern Iran are an integral part of the Arabia-Eurasia collision. Linked strike-slip and thrust/reverse-fault systems in this mountain belt are characterized by slow loading rates, and large earthquakes are highly disparate in space and time. Similar to other intracontinental deformation zones such a pattern of tectonic activity is still insufficiently understood, because recurrence intervals between seismic events may be on the order of thousands of years, and are thus beyond the resolution of short term measurements based on GPS or instrumentally recorded seismicity. This study bridges the gap of deformation processes on different time scales. In particular, my investigation focuses on deformation on the Quaternary time scale, beyond present-day deformation rates, and it uses present-day and paleotectonic characteristics to model fault behavior. The study includes data based on structural and geomorphic mapping, faultkinematic analysis, DEM-based morphometry, and numerical fault-interaction modeling. In order to better understand the long- to short term behavior of such complex fault systems, I used geomorphic surfaces as strain markers and dated fluvial and alluvial surfaces using terrestrial cosmogenic nuclides (TCN, 10Be, 26Al, 36Cl) and optically stimulated luminescence (OSL). My investigation focuses on the seismically active Mosha-Fasham fault (MFF) and the seismically virtually inactive North Tehran Thrust (NTT), adjacent to the Tehran metropolitan area. Fault-kinematic data reveal an early mechanical linkage of the NTT and MFF during an earlier dextral transpressional stage, when the shortening direction was oriented northwest. This regime was superseded by Pliocene to Recent NE-oriented shortening, which caused thrusting and sinistral strike-slip faulting. In the course of this kinematic changeover, the NTT and MFF were reactivated and incorporated into a nascent transpressional duplex, which has significantly affected landscape evolution in this part of the range. Two of three distinctive features which characterize topography and relief in the study area can be directly related to their location inside the duplex array and are thus linked to interaction between eastern MFF and NTT, and between western MFF and Taleghan fault, respectively. To account for inferred inherited topography from the previous dextral-transpression regime, a new concept of tectonic landscape characterization has been used. Accordingly, I define simple landscapes as those environments, which have developed during the influence of a sustained tectonic regime. In contrast, composite landscapes contain topographic elements inherited from previous tectonic conditions that are inconsistent with the regional present-day stress field and kinematic style. Using numerical fault-interaction modeling with different tectonic boundary conditions, I calculated synoptic snapshots of artificial topography to compare it with the real topographic metrics. However, in the Alborz mountains, E-W faults are favorably oriented to accommodate the entire range of NW- to NE-directed compression. These faults show the highest total displacement which might indicate sustained faulting under changing boundary conditions. In contrast to the fault system within and at the flanks of the Alborz mountains, Quaternary deformation in the adjacent Tehran plain is characterized by oblique motion and thrust and strike-slip fault systems. In this morphotectonic province fault-propagation folding along major faults, limited strike-slip motion, and en-{\´e}chelon arrays of second-order upper plate thrusts are typical. While the Tehran plain is characterized by young deformation phenomena, the majority of faulting took place in the early stages of the Quaternary and during late Pliocene time. TCN-dating, which was performed for the first time on geomorphic surfaces in the Tehran plain, revealed that the oldest two phases of alluviation (units A and B) must be older than late Pleistocene. While urban development in Tehran increasingly covers and obliterates the active fault traces, the present-day kinematic style, the vestiges of formerly undeformed Quaternary landforms, and paleo earthquake indicators from the last millennia attest to the threat that these faults and their related structures pose for the megacity.}, language = {en} } @phdthesis{Wolff2010, author = {Wolff, Markus}, title = {Geovisual methods and techniques for the development of three-dimensional tactical intelligence assessments}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50446}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {This thesis presents methods, techniques and tools for developing three-dimensional representations of tactical intelligence assessments. Techniques from GIScience are combined with crime mapping methods. The range of methods applied in this study provides spatio-temporal GIS analysis as well as 3D geovisualisation and GIS programming. The work presents methods to enhance digital three-dimensional city models with application specific thematic information. This information facilitates further geovisual analysis, for instance, estimations of urban risks exposure. Specific methods and workflows are developed to facilitate the integration of spatio-temporal crime scene analysis results into 3D tactical intelligence assessments. Analysis comprises hotspot identification with kernel-density-estimation techniques (KDE), LISA-based verification of KDE hotspots as well as geospatial hotspot area characterisation and repeat victimisation analysis. To visualise the findings of such extensive geospatial analysis, three-dimensional geovirtual environments are created. Workflows are developed to integrate analysis results into these environments and to combine them with additional geospatial data. The resulting 3D visualisations allow for an efficient communication of complex findings of geospatial crime scene analysis.}, language = {en} } @phdthesis{Gloeckner2010, author = {Gl{\"o}ckner, Olaf}, title = {Immigrated Russian Jewish elites in Israel and Germany after 1990}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50369}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Russian Jews who left the Former Soviet Union (FSU) and its Successor States after 1989 are considered as one of the best qualified migrants group worldwide. In the preferred countries of destination (Israel, the United States and Germany) they are well-known for cultural self-assertion, strong social upward mobility and manifold forms of self organisation and empowerment. Using Suzanne Kellers sociological model of "Strategic Elites", it easily becomes clear that a huge share of the Russian Jewish Immigrants in Germany and Israel are part of various elites due to their qualification and high positions in the FSU - first of all professional, cultural and intellectual elites ("Intelligentsija"). The study aimed to find out to what extent developments of cultural self-assertion, of local and transnational networking and of ethno-cultural empowerment are supported or even initiated by the immigrated (Russian Jewish) Elites. The empirical basis for this study have been 35 half-structured expert interviews with Russian Jews in both countries (Israel, Germany) - most of them scholars, artists, writers, journalists/publicists, teachers, engineers, social workers, students and politicians. The qualitative analysis of the interview material in Israel and Germany revealed that there are a lot of commonalities but also significant differences. It was obvious that almost all of the interview partners remained to be linked with Russian speaking networks and communities, irrespective of their success (or failure) in integration into the host societies. Many of them showed self-confidence with regard to the groups' amazing professional resources (70\% of the adults with academic degree), and the cultural, professional and political potential of the FSU immigrants was usually considered as equal to those of the host population(s). Thus, the immigrants' interest in direct societal participation and social acceptance was accordingly high. Assimilation was no option. For the Russian Jewish "sense of community" in Israel and Germany, Russian Language, Arts and general Russian culture have remained of key importance. The Immigrants do not feel an insuperable contradiction when feeling "Russian" in cultural terms, "Jewish" in ethnical terms and "Israeli" / "German" in national terms - in that a typical case of additive identity shaping what is also significant for the Elites of these Immigrants. Tendencies of ethno-cultural self organisation - which do not necessarily hinder impressing individual careers in the new surroundings - are more noticeable in Israel. Thus, a part of the Russian Jewish Elites has responded to social exclusion, discrimination or blocking by local population (and by local elites) with intense efforts to build (Russian Jewish) Associations, Media, Educational Institutions and even Political Parties. All in all, the results of this study do very much contradict popular stereotypes of the Russian Jewish Immigrant as a pragmatic, passive "Homo Sovieticus". Among the Interview Partners in this study, civil-societal commitment was not the exception but rather the rule. Traditional activities of the early, legendary Russian „Intelligentsija" were marked by smooth transitions from arts, education and societal/political commitment. There seem to be certain continuities of this self-demand in some of the Russian Jewish groups in Israel. Though, nothing comparable could be drawn from the Interviews with the Immigrants in Germany. Thus, the myth and self-demand of Russian "Intelligentsija" is irrelevant for collective discourses among Russian Jews in Germany.}, language = {en} } @phdthesis{Boeniger2010, author = {B{\"o}niger, Urs}, title = {Attributes and their potential to analyze and interpret 3D GPR data}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-50124}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Based on technological advances made within the past decades, ground-penetrating radar (GPR) has become a well-established, non-destructive subsurface imaging technique. Catalyzed by recent demands for high-resolution, near-surface imaging (e.g., the detection of unexploded ordnances and subsurface utilities, or hydrological investigations), the quality of today's GPR-based, near-surface images has significantly matured. At the same time, the analysis of oil and gas related reflection seismic data sets has experienced significant advances. Considering the sensitivity of attribute analysis with respect to data positioning in general, and multi-trace attributes in particular, trace positioning accuracy is of major importance for the success of attribute-based analysis flows. Therefore, to study the feasibility of GPR-based attribute analyses, I first developed and evaluated a real-time GPR surveying setup based on a modern tracking total station (TTS). The combination of current GPR systems capability of fusing global positioning system (GPS) and geophysical data in real-time, the ability of modern TTS systems to generate a GPS-like positional output and wireless data transmission using radio modems results in a flexible and robust surveying setup. To elaborate the feasibility of this setup, I studied the major limitations of such an approach: system cross-talk and data delays known as latencies. Experimental studies have shown that when a minimal distance of ~5 m between the GPR and the TTS system is considered, the signal-to-noise ratio of the acquired GPR data using radio communication equals the one without radio communication. To address the limitations imposed by system latencies, inherent to all real-time data fusion approaches, I developed a novel correction (calibration) strategy to assess the gross system latency and to correct for it. This resulted in the centimeter trace accuracy required by high-frequency and/or three-dimensional (3D) GPR surveys. Having introduced this flexible high-precision surveying setup, I successfully demonstrated the application of attribute-based processing to GPR specific problems, which may differ significantly from the geological ones typically addressed by the oil and gas industry using seismic data. In this thesis, I concentrated on archaeological and subsurface utility problems, as they represent typical near-surface geophysical targets. Enhancing 3D archaeological GPR data sets using a dip-steered filtering approach, followed by calculation of coherency and similarity, allowed me to conduct subsurface interpretations far beyond those obtained by classical time-slice analyses. I could show that the incorporation of additional data sets (magnetic and topographic) and attributes derived from these data sets can further improve the interpretation. In a case study, such an approach revealed the complementary nature of the individual data sets and, for example, allowed conclusions about the source location of magnetic anomalies by concurrently analyzing GPR time/depth slices to be made. In addition to archaeological targets, subsurface utility detection and characterization is a steadily growing field of application for GPR. I developed a novel attribute called depolarization. Incorporation of geometrical and physical feature characteristics into the depolarization attribute allowed me to display the observed polarization phenomena efficiently. Geometrical enhancement makes use of an improved symmetry extraction algorithm based on Laplacian high-boosting, followed by a phase-based symmetry calculation using a two-dimensional (2D) log-Gabor filterbank decomposition of the data volume. To extract the physical information from the dual-component data set, I employed a sliding-window principle component analysis. The combination of the geometrically derived feature angle and the physically derived polarization angle allowed me to enhance the polarization characteristics of subsurface features. Ground-truth information obtained by excavations confirmed this interpretation. In the future, inclusion of cross-polarized antennae configurations into the processing scheme may further improve the quality of the depolarization attribute. In addition to polarization phenomena, the time-dependent frequency evolution of GPR signals might hold further information on the subsurface architecture and/or material properties. High-resolution, sparsity promoting decomposition approaches have recently had a significant impact on the image and signal processing community. In this thesis, I introduced a modified tree-based matching pursuit approach. Based on different synthetic examples, I showed that the modified tree-based pursuit approach clearly outperforms other commonly used time-frequency decomposition approaches with respect to both time and frequency resolutions. Apart from the investigation of tuning effects in GPR data, I also demonstrated the potential of high-resolution sparse decompositions for advanced data processing. Frequency modulation of individual atoms themselves allows to efficiently correct frequency attenuation effects and improve resolution based on shifting the average frequency level. GPR-based attribute analysis is still in its infancy. Considering the growing widespread realization of 3D GPR studies there will certainly be an increasing demand towards improved subsurface interpretations in the future. Similar to the assessment of quantitative reservoir properties through the combination of 3D seismic attribute volumes with sparse well-log information, parameter estimation in a combined manner represents another step in emphasizing the potential of attribute-driven GPR data analyses.}, language = {en} } @phdthesis{Tronci2010, author = {Tronci, Giuseppe}, title = {Synthesis, characterization, and biological evaluation of gelatin-based scaffolds}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49727}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {This work presents the development of entropy-elastic gelatin based networks in the form of films or scaffolds. The materials have good prospects for biomedical applications, especially in the context of bone regeneration. Entropy-elastic gelatin based hydrogel films with varying crosslinking densities were prepared with tailored mechanical properties. Gelatin was covalently crosslinked above its sol gel transition, which suppressed the gelatin chain helicity. Hexamethylene diisocyanate (HDI) or ethyl ester lysine diisocyanate (LDI) were applied as chemical crosslinkers, and the reaction was conducted either in dimethyl sulfoxide (DMSO) or water. Amorphous films were prepared as measured by Wide Angle X-ray Scattering (WAXS), with tailorable degrees of swelling (Q: 300-800 vol. \%) and wet state Young's modulus (E: 70 740 kPa). Model reactions showed that the crosslinking reaction resulted in a combination of direct crosslinks (3-13 mol.-\%), grafting (5-40 mol.-\%), and blending of oligoureas (16-67 mol.-\%). The knowledge gained with this bulk material was transferred to the integrated process of foaming and crosslinking to obtain porous 3-D gelatin-based scaffolds. For this purpose, a gelatin solution was foamed in the presence of a surfactant, Saponin, and the resulting foam was fixed by chemical crosslinking with a diisocyanate. The amorphous crosslinked scaffolds were synthesized with varied gelatin and HDI concentrations, and analyzed in the dry state by micro computed tomography (µCT, porosity: 65±11-73±14 vol.-\%), and scanning electron microscopy (SEM, pore size: 117±28-166±32 µm). Subsequently, the work focused on the characterization of the gelatin scaffolds in conditions relevant to biomedical applications. Scaffolds showed high water uptake (H: 630-1680 wt.-\%) with minimal changes in outer dimension. Since a decreased scaffold pore size (115±47-130±49 µm) was revealed using confocal laser scanning microscopy (CLSM) upon wetting, the form stability could be explained. Shape recoverability was observed after removal of stress when compressing wet scaffolds, while dry scaffolds maintained the compressed shape. This was explained by a reduction of the glass transition temperature upon equilibration with water (dynamic mechanical analysis at varied temperature (DMTA)). The composition dependent compression moduli (Ec: 10 50 kPa) were comparable to the bulk micromechanical Young's moduli, which were measured by atomic force microscopy (AFM). The hydrolytic degradation profile could be adjusted, and a controlled decrease of mechanical properties was observed. Partially-degraded scaffolds displayed an increase of pore size. This was likely due to the pore wall disintegration during degradation, which caused the pores to merge. The scaffold cytotoxicity and immunologic responses were analyzed. The porous scaffolds enabled proliferation of human dermal fibroblasts within the implants (up to 90 µm depth). Furthermore, indirect eluate tests were carried out with L929 cells to quantify the material cytotoxic response. Here, the effect of the sterilization method (Ethylene oxide sterilization), crosslinker, and surfactant were analyzed. Fully cytocompatible scaffolds were obtained by using LDI as crosslinker and PEO40 PPO20-PEO40 as surfactant. These investigations were accompanied by a study of the endotoxin material contamination. The formation of medical-grade materials was successfully obtained (<0.5 EU/mL) by using low-endotoxin gelatin and performing all synthetic steps in a laminar flow hood.}, language = {en} } @phdthesis{Scherler2010, author = {Scherler, Dirk}, title = {Climate variability and glacial dynamics in the Himalaya}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49871}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {In den Hochgebirgen Asiens bedecken Gletscher eine Fl{\"a}che von ungef{\"a}hr 115,000 km² und ergeben damit, neben Gr{\"o}nland und der Antarktis, eine der gr{\"o}ßten Eisakkumulationen der Erde. Die Sensibilit{\"a}t der Gletscher gegen{\"u}ber Klimaschwankungen macht sie zu wertvollen pal{\"a}oklimatischen Archiven in Hochgebirgen, aber gleichzeitig auch anf{\"a}llig gegen{\"u}ber rezenter und zuk{\"u}nftiger globaler Erw{\"a}rmung. Dies kann vor allem in dicht besiedelten Gebieten S{\"u}d-, Ost- und Zentralasiens zu großen Problem f{\"u}hren, in denen Gletscher- und Schnee-Schmelzw{\"a}sser eine wichtige Ressource f{\"u}r Landwirtschaft und Stromerzeugung darstellen. Eine erfolgreiche Prognose des Gletscherverhaltens in Reaktion auf den Klimawandel und die Minderung der sozio{\"o}konomischen Auswirkungen erfordert fundierte Kenntnisse der klimatischen Steuerungsfaktoren und der Dynamik asiatischer Gletscher. Aufgrund ihrer Abgeschiedenheit und dem erschwerten Zugang gibt es nur wenige glaziologische Gel{\"a}ndestudien, die zudem r{\"a}umlich und zeitlich sehr begrenzt sind. Daher fehlen bisher grundlegende Informationen {\"u}ber die Mehrzahl asiatischer Gletscher. In dieser Arbeit benutze ich verschiedene Methoden, um die Dynamik asiatischer Gletscher auf mehreren Zeitskalen zu untersuchen. Erstens teste ich eine Methode zur pr{\"a}zisen satelliten-gest{\"u}tzten Messung von Gletscheroberfl{\"a}chen-Geschwindigkeiten. Darauf aufbauend habe ich eine umfassende regionale Erhebung der Fliessgeschwindigkeiten und Frontdynamik asiatischer Gletscher f{\"u}r die Jahre 2000 bis 2008 durchgef{\"u}hrt. Der gewonnene Datensatz erlaubt einmalige Einblicke in die topographischen und klimatischen Steuerungsfaktoren der Gletscherfließgeschwindigkeiten in den Gebirgsregionen Hochasiens. Insbesondere dokumentieren die Daten rezent ungleiches Verhalten der Gletscher im Karakorum und im Himalaja, welches ich auf die konkurrierenden klimatischen Einfl{\"u}sse der Westwinddrift im Winter und des Indischen Monsuns im Sommer zur{\"u}ckf{\"u}hre. Zweitens untersuche ich, ob klimatisch bedingte Ost-West Unterschiede im Gletscherverhalten auch auf l{\"a}ngeren Zeitskalen eine Rolle spielen und gegebenenfalls f{\"u}r dokumentierte regional asynchrone Gletschervorst{\"o}ße relevant sind. Dazu habe ich mittels kosmogener Nuklide Oberfl{\"a}chenalter von erratischen Bl{\"o}cken auf Mor{\"a}nen ermittelt und eine glaziale Chronologie f{\"u}r das obere Tons Tal, in den Quellgebieten des Ganges, erstellt. Dieses Gebiet befindet sich in der {\"U}bergangszone von monsunaler zu Westwind beeinflusster Feuchtigkeitszufuhr und ist damit ideal gelegen, um die Auswirkungen dieser beiden atmosph{\"a}rischen Zirkulationssysteme auf Gletschervorst{\"o}ße zu untersuchen. Die ermittelte glaziale Chronologie dokumentiert mehrere Gletscherschwankungen w{\"a}hrend des Endstadiums der letzten Pleistoz{\"a}nen Vereisung und w{\"a}hrend des Holz{\"a}ns. Diese weisen darauf hin, dass Gletscherschwankungen im westlichen Himalaja weitestgehend synchron waren und auf graduelle glaziale-interglaziale Temperaturver{\"a}nderungen, {\"u}berlagert von monsunalen Niederschlagsschwankungen h{\"o}herer Frequenz, zur{\"u}ck zu f{\"u}hren sind. In einem dritten Schritt kombiniere ich Satelliten-Klimadaten mit Eisfluss-Absch{\"a}tzungen und topographischen Analysen, um den Einfluss der Gletscher Hochasiens auf die Reliefentwicklung im Hochgebirge zu untersuchen. Die Ergebnisse dokumentieren ausgepr{\"a}gte meridionale Unterschiede im Grad und im Stil der Vergletscherung und glazialen Erosion in Abh{\"a}ngigkeit von topographischen und klimatischen Faktoren. Gegens{\"a}tzlich zu bisherigen Annahmen deuten die Daten darauf hin, dass das monsunale Klima im zentralen Himalaja die glaziale Erosion schw{\"a}cht und durch den Erhalt einer steilen orographischen Barriere das Tibet Plateau vor lateraler Zerschneidung bewahrt. Die Ergebnisse dieser Arbeit dokumentieren, wie klimatische und topographische Gradienten die Gletscherdynamik in den Hochgebirgen Asiens auf Zeitskalen von 10^0 bis 10^6 Jahren beeinflussen. Die Reaktionszeit der Gletscher auf Klimaver{\"a}nderungen sind eng an Eigenschaften wie Schuttbedeckung und Neigung gekoppelt, welche ihrerseits von den topographischen Verh{\"a}ltnissen bedingt sind. Derartige Einflussfaktoren m{\"u}ssen bei pal{\"a}oklimatischen Rekonstruktion und Vorhersagen {\"u}ber die Entwicklung asiatischer Gletscher ber{\"u}cksichtigt werden. Desweiteren gehen die regionalen topographischen Unterschiede der vergletscherten Gebiete Asiens teilweise auf klimatische Gradienten und den langfristigen Einfluss der Gletscher auf die topographische Entwicklung des Gebirgssystems zur{\"u}ck.}, language = {en} } @phdthesis{Guse2010, author = {Guse, Bj{\"o}rn Felix}, title = {Improving flood frequency analysis by integration of empirical and probabilistic regional envelope curves}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49265}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Flood design necessitates discharge estimates for large recurrence intervals. However, in a flood frequency analysis, the uncertainty of discharge estimates increases with higher recurrence intervals, particularly due to the small number of available flood data. Furthermore, traditional distribution functions increase unlimitedly without consideration of an upper bound discharge. Hence, additional information needs to be considered which is representative for high recurrence intervals. Envelope curves which bound the maximum observed discharges of a region are an adequate regionalisation method to provide additional spatial information for the upper tail of a distribution function. Probabilistic regional envelope curves (PRECs) are an extension of the traditional empirical envelope curve approach, in which a recurrence interval is estimated for a regional envelope curve (REC). The REC is constructed for a homogeneous pooling group of sites. The estimation of this recurrence interval is based on the effective sample years of data considering the intersite dependence among all sites of the pooling group. The core idea of this thesis was an improvement of discharge estimates for high recurrence intervals by integrating empirical and probabilistic regional envelope curves into the flood frequency analysis. Therefore, the method of probabilistic regional envelope curves was investigated in detail. Several pooling groups were derived by modifying candidate sets of catchment descriptors and settings of two different pooling methods. These were used to construct PRECs. A sensitivity analysis shows the variability of discharges and the recurrence intervals for a given site due to the different assumptions. The unit flood of record which governs the intercept of PREC was determined as the most influential aspect. By separating the catchments into nested and unnested pairs, the calculation algorithm for the effective sample years of data was refined. In this way, the estimation of the recurrence intervals was improved, and therefore the use of different parameter sets for nested and unnested pairs of catchments is recommended. In the second part of this thesis, PRECs were introduced into a distribution function. Whereas in the traditional approach only discharge values are used, PRECs provide a discharge and its corresponding recurrence interval. Hence, a novel approach was developed, which allows a combination of the PREC results with the traditional systematic flood series while taking the PREC recurrence interval into consideration. An adequate mixed bounded distribution function was presented, which in addition to the PREC results also uses an upper bound discharge derived by an empirical envelope curve. By doing so, two types of additional information which are representative for the upper tail of a distribution function were included in the flood frequency analysis. The integration of both types of additional information leads to an improved discharge estimation for recurrence intervals between 100 and 1000 years.}, language = {en} } @phdthesis{Awad2010, author = {Awad, Ahmed Mahmoud Hany Aly}, title = {A compliance management framework for business process models}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49222}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Companies develop process models to explicitly describe their business operations. In the same time, business operations, business processes, must adhere to various types of compliance requirements. Regulations, e.g., Sarbanes Oxley Act of 2002, internal policies, best practices are just a few sources of compliance requirements. In some cases, non-adherence to compliance requirements makes the organization subject to legal punishment. In other cases, non-adherence to compliance leads to loss of competitive advantage and thus loss of market share. Unlike the classical domain-independent behavioral correctness of business processes, compliance requirements are domain-specific. Moreover, compliance requirements change over time. New requirements might appear due to change in laws and adoption of new policies. Compliance requirements are offered or enforced by different entities that have different objectives behind these requirements. Finally, compliance requirements might affect different aspects of business processes, e.g., control flow and data flow. As a result, it is infeasible to hard-code compliance checks in tools. Rather, a repeatable process of modeling compliance rules and checking them against business processes automatically is needed. This thesis provides a formal approach to support process design-time compliance checking. Using visual patterns, it is possible to model compliance requirements concerning control flow, data flow and conditional flow rules. Each pattern is mapped into a temporal logic formula. The thesis addresses the problem of consistency checking among various compliance requirements, as they might stem from divergent sources. Also, the thesis contributes to automatically check compliance requirements against process models using model checking. We show that extra domain knowledge, other than expressed in compliance rules, is needed to reach correct decisions. In case of violations, we are able to provide a useful feedback to the user. The feedback is in the form of parts of the process model whose execution causes the violation. In some cases, our approach is capable of providing automated remedy of the violation.}, language = {en} } @phdthesis{Moerbt2010, author = {M{\"o}rbt, Nora}, title = {Differential proteome analysis of human lung epithelial cells following exposure to aromatic volatile organic compounds}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49257}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {The widespread usage of products containing volatile organic compounds (VOC) has lead to a general human exposure to these chemicals in work places or homes being suspected to contribute to the growing incidence of environmental diseases. Since the causal molecular mechanisms for the development of these disorders are not completely understood, the overall objective of this thesis was to investigate VOC-mediated molecular effects on human lung cells in vitro at VOC concentrations comparable to exposure scenarios below current occupational limits. Although differential expression of single proteins in response to VOCs has been reported, effects on complex protein networks (proteome) have not been investigated. However, this information is indispensable when trying to ascertain a mechanism for VOC action on the cellular level and establishing preventive strategies. For this study, the alveolar epithelial cell line A549 has been used. This cell line, cultured in a two-phase (air/liquid) model allows the most direct exposure and had been successfully applied for the analysis of inflammatory effects in response to VOCs. Mass spectrometric identification of 266 protein spots provided the first proteomic map of A549 cell line to this extent that may foster future work with this frequently used cellular model. The distribution of three typical air contaminants, monochlorobenzene (CB), styrene and 1,2 dichlorobenzene (1,2-DCB), between gas and liquid phase of the exposure model has been analyzed by gas chromatography. The obtained VOC partitioning was in agreement with available literature data. Subsequently the adapted in vitro system has been successfully employed to characterize the effects of the aromatic compound styrene on the proteome of A549 cells (Chapter 4). Initially, the cell toxicity has been assessed in order to ensure that most of the concentrations used in the following proteomic approach were not cytotoxic. Significant changes in abundance and phosphorylation in the total soluble protein fraction of A549 cells have been detected following styrene exposure. All proteins have been identified using mass spectrometry and the main cellular functions have been assigned. Validation experiments on protein and transcript level confirmed the results of the 2-DE experiments. From the results, two main cellular pathways have been identified that were induced by styrene: the cellular oxidative stress response combined with moderate pro-apoptotic signaling. Measurement of cellular reactive oxygen species (ROS) as well as the styrene-mediated induction of oxidative stress marker proteins confirmed the hypothesis of oxidative stress as the main molecular response mechanism. Finally, adducts of cellular proteins with the reactive styrene metabolite styrene 7,8 oxide (SO) have been identified. Especially the SO-adducts observed at both the reactive centers of thioredoxin reductase 1, which is a key element in the control of the cellular redox state, may be involved in styrene-induced ROS formation and apoptosis. A similar proteomic approach has been carried out with the halobenzenes CB and 1,2-DCB (Chapter 5). In accordance with previous findings, cell toxicity assessment showed enhanced toxicity compared to the one caused by styrene. Significant changes in abundance and phosphorylation of total soluble proteins of A549 cells have been detected following exposure to subtoxic concentrations of CB and 1,2-DCB. All proteins have been identified using mass spectrometry and the main cellular functions have been assigned. As for the styrene experiment, the results indicated two main pathways to be affected in the presence of chlorinated benzenes, cell death signaling and oxidative stress response. The strong induction of pro-apoptotic signaling has been confirmed for both treatments by detection of the cleavage of caspase 3. Likewise, the induction of redox-sensitive protein species could be correlated to an increased cellular level of ROS observed following CB treatment. Finally, common mechanisms in the cellular response to aromatic VOCs have been investigated (Chapter 6). A similar number (4.6-6.9\%) of all quantified protein spots showed differential expression (p<0.05) following cell exposure to styrene, CB or 1,2-DCB. However, not more than three protein spots showed significant regulation in the same direction for all three volatile compounds: voltage-dependent anion-selective channel protein 2, peroxiredoxin 1 and elongation factor 2. However, all of these proteins are important molecular targets in stress- and cell death-related signaling pathways.}, language = {en} } @phdthesis{Ruch2010, author = {Ruch, Jo{\"e}l}, title = {Volcano deformation analysis in the Lazufre area (central Andes) using geodetic and geological observations}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-47361}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Large-scale volcanic deformation recently detected by radar interferometry (InSAR) provides new information and thus new scientific challenges for understanding volcano-tectonic activity and magmatic systems. The destabilization of such a system at depth noticeably affects the surrounding environment through magma injection, ground displacement and volcanic eruptions. To determine the spatiotemporal evolution of the Lazufre volcanic area located in the central Andes, we combined short-term ground displacement acquired by InSAR with long-term geological observations. Ground displacement was first detected using InSAR in 1997. By 2008, this displacement affected 1800 km2 of the surface, an area comparable in size to the deformation observed at caldera systems. The original displacement was followed in 2000 by a second, small-scale, neighbouring deformation located on the Lastarria volcano. We performed a detailed analysis of the volcanic structures at Lazufre and found relationships with the volcano deformations observed with InSAR. We infer that these observations are both likely to be the surface expression of a long-lived magmatic system evolving at depth. It is not yet clear whether Lazufre may trigger larger unrest or volcanic eruptions; however, the second deformation detected at Lastarria and the clear increase of the large-scale deformation rate make this an area of particular interest for closer continuous monitoring.}, language = {en} } @phdthesis{Ksianzou2010, author = {Ksianzou, Viachaslau}, title = {Second-order nonlinear optical interactions and cascading effects in thinorganic films}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49186}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {The presented work describes new concepts of fast switching elements based on principles of photonics. The waveguides working in visible and infra-red ranges are put in a basis of these elements. And as materials for manufacturing of waveguides the transparent polymers, dopped by molecules of the dyes possessing second order nonlinear-optical properties are proposed. The work shows how nonlinear-optical processes in such structures can be implemented by electro-optical and opto-optical control circuit signals. In this paper we consider the complete cycle of fabrication of several types of integral photonic elements. The theoretical analysis of high-intensity beam propagation in media with second-order optical nonlinearity is performed. Quantitative estimations of necessary conditions of occurrence of the nonlinear-optical phenomena of the second order taking into account properties of used materials are made. The paper describes the various stages of manufacture of the basic structure of the integrated photonics: a planar waveguide. Using the finite element method the structure of the electromagnetic field inside the waveguide in different modes was analysed. A separate part of the work deals with the creation of composite organic materials with high optical nonlinearity. Using the methods of quantum chemistry, the dependence of nonlinear properties of dye molecules from its structure were investigated in details. In addition, the paper discusses various methods of inducing of an optical nonlinearity in dye-doping of polymer films. In the work, for the first time is proposed the use of spatial modulation of nonlinear properties of waveguide according Fibonacci law. This allows involving several different nonlinear optical processes simultaneously. The final part of the work describes various designs of integrated optical modulators and switches constructed of organic nonlinear optical waveguides. A practical design of the optical modulator based on Mach-Zehnder interferometer made by a photolithography on polymer film is presented.}, language = {en} } @phdthesis{Liesenjohann2010, author = {Liesenjohann, Thilo}, title = {Foraging in space and time}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-48562}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {All animals are adapted to the environmental conditions of the habitat they chose to live in. It was the aim of this PhD-project, to show which behavioral strategies are expressed as mechanisms to cope with the constraints, which contribute to the natural selection pressure acting on individuals. For this purpose, small mammals were exposed to different levels and types of predation risk while actively foraging. Individuals were either exposed to different predator types (airborne or ground) or combinations of both, or to indirect predators (nest predators). Risk was assumed to be distributed homogeneously, so changing the habitat or temporal adaptations where not regarded as potential options. Results show that wild-caught voles have strategic answers to this homogeneously distributed risk, which is perceived by tactile, olfactory or acoustic cues. Thus, they do not have to know an absolut quality (e.g., in terms of food provisioning and risk levels of all possible habitats), but they can adapt their behavior to the actual circumstances. Deriving risk uniform levels from cues and adjusting activity levels to the perceived risk is an option to deal with predators of the same size or with unforeseeable attack rates. Experiments showed that as long as there are no safe places or times, it is best to reduce activity and behave as inconspicuous as possible as long as the costs of missed opportunities do not exceed the benefits of a higher survival probability. Test showed that these costs apparently grow faster for males than for females, especially in times of inactivity. This is supported by strong predatory pressure on the most active groups of rodents (young males, sexually active or dispersers) leading to extremely female-biased operative sex ratios in natural populations. Other groups of animals, those with parental duties such as nest guarding, for example, have to deal with the actual risk in their habitat as well. Strategies to indirect predation pressure were tested by using bank vole mothers, confronted with a nest predator that posed no actual threat to themselves but to their young (Sorex araneus). They reduced travelling and concentrated their effort in the presence of shrews, independent of the different nutritional provisioning of food by varying resource levels due to the different seasons. Additionally, they exhibited nest-guarding strategies by not foraging in the vicinity of the nest site in order to reduce conspicuous scent marks. The repetition of the experiment in summer and autumn showed that changing environmental constraints can have a severe impact on results of outdoor studies. In our case, changing resource levels changed the type of interaction between the two species. The experiments show that it is important to analyze decision making and optimality models on an individual level, and, when that is not possible (maybe because of the constraints of field work), groups of animals should be classified by using the least common denominator that can be identified (such as sex, age, origin or kinship). This will control for the effects of the sex or stage of life history or the individual´s reproductive and nutritional status on decision making and will narrow the wide behavioral variability associated with the complex term of optimality.}, language = {en} } @phdthesis{Creutzfeldt2010, author = {Creutzfeldt, Noah Angelo Benjamin}, title = {The effect of water storages on temporal gravity measurements and the benefits for hydrology}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-48575}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Temporal gravimeter observations, used in geodesy and geophysics to study variation of the Earth's gravity field, are influenced by local water storage changes (WSC) and - from this perspective - add noise to the gravimeter signal records. At the same time, the part of the gravity signal caused by WSC may provide substantial information for hydrologists. Water storages are the fundamental state variable of hydrological systems, but comprehensive data on total WSC are practically inaccessible and their quantification is associated with a high level of uncertainty at the field scale. This study investigates the relationship between temporal gravity measurements and WSC in order to reduce the hydrological interfering signal from temporal gravity measurements and to explore the value of temporal gravity measurements for hydrology for the superconducting gravimeter (SG) of the Geodetic Observatory Wettzell, Germany. A 4D forward model with a spatially nested discretization domain was developed to simulate and calculate the local hydrological effect on the temporal gravity observations. An intensive measurement system was installed at the Geodetic Observatory Wettzell and WSC were measured in all relevant storage components, namely groundwater, saprolite, soil, top soil and snow storage. The monitoring system comprised also a suction-controlled, weighable, monolith-filled lysimeter, allowing an all time first comparison of a lysimeter and a gravimeter. Lysimeter data were used to estimate WSC at the field scale in combination with complementary observations and a hydrological 1D model. Total local WSC were derived, uncertainties were assessed and the hydrological gravity response was calculated from the WSC. A simple conceptual hydrological model was calibrated and evaluated against records of a superconducting gravimeter, soil moisture and groundwater time series. The model was evaluated by a split sample test and validated against independently estimated WSC from the lysimeter-based approach. A simulation of the hydrological gravity effect showed that WSC of one meter height along the topography caused a gravity response of 52 µGal, whereas, generally in geodesy, on flat terrain, the same water mass variation causes a gravity change of only 42 µGal (Bouguer approximation). The radius of influence of local water storage variations can be limited to 1000 m and 50 \% to 80 \% of the local hydro¬logical gravity signal is generated within a radius of 50 m around the gravimeter. At the Geodetic Observatory Wettzell, WSC in the snow pack, top soil, unsaturated saprolite and fractured aquifer are all important terms of the local water budget. With the exception of snow, all storage components have gravity responses of the same order of magnitude and are therefore relevant for gravity observations. The comparison of the total hydrological gravity response to the gravity residuals obtained from the SG, showed similarities in both short-term and seasonal dynamics. However, the results demonstrated the limitations of estimating total local WSC using hydrological point measurements. The results of the lysimeter-based approach showed that gravity residuals are caused to a larger extent by local WSC than previously estimated. A comparison of the results with other methods used in the past to correct temporal gravity observations for the local hydrological influence showed that the lysimeter measurements improved the independent estimation of WSC significantly and thus provided a better way of estimating the local hydrological gravity effect. In the context of hydrological noise reduction, at sites where temporal gravity observations are used for geophysical studies beyond local hydrology, the installation of a lysimeter in combination with complementary hydrological measurements is recommended. From the hydrological view point, using gravimeter data as a calibration constraint improved the model results in comparison to hydrological point measurements. Thanks to their capacity to integrate over different storage components and a larger area, gravimeters provide generalized information on total WSC at the field scale. Due to their integrative nature, gravity data must be interpreted with great care in hydrological studies. However, gravimeters can serve as a novel measurement instrument for hydrology and the application of gravimeters especially designed to study open research questions in hydrology is recommended.}, language = {en} } @phdthesis{Ahnert2010, author = {Ahnert, Karsten}, title = {Compactons in strongly nonlinear lattices}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-48539}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {In the present work, we study wave phenomena in strongly nonlinear lattices. Such lattices are characterized by the absence of classical linear waves. We demonstrate that compactons - strongly localized solitary waves with tails decaying faster than exponential - exist and that they play a major role in the dynamics of the system under consideration. We investigate compactons in different physical setups. One part deals with lattices of dispersively coupled limit cycle oscillators which find various applications in natural sciences such as Josephson junction arrays or coupled Ginzburg-Landau equations. Another part deals with Hamiltonian lattices. Here, a prominent example in which compactons can be found is the granular chain. In the third part, we study systems which are related to the discrete nonlinear Schr{\"o}dinger equation describing, for example, coupled optical wave-guides or the dynamics of Bose-Einstein condensates in optical lattices. Our investigations are based on a numerical method to solve the traveling wave equation. This results in a quasi-exact solution (up to numerical errors) which is the compacton. Another ansatz which is employed throughout this work is the quasi-continuous approximation where the lattice is described by a continuous medium. Here, compactons are found analytically, but they are defined on a truly compact support. Remarkably, both ways give similar qualitative and quantitative results. Additionally, we study the dynamical properties of compactons by means of numerical simulation of the lattice equations. Especially, we concentrate on their emergence from physically realizable initial conditions as well as on their stability due to collisions. We show that the collisions are not exactly elastic but that a small part of the energy remains at the location of the collision. In finite lattices, this remaining part will then trigger a multiple scattering process resulting in a chaotic state.}, language = {en} } @phdthesis{SanchezBarriga2010, author = {S{\´a}nchez-Barriga, Jaime}, title = {A photoemission study of quasiparticle excitations, electron-correlation effects and magnetization dynamics in thin magnetic systems}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-48499}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {This thesis is focused on the electronic, spin-dependent and dynamical properties of thin magnetic systems. Photoemission-related techniques are combined with synchrotron radiation to study the spin-dependent properties of these systems in the energy and time domains. In the first part of this thesis, the strength of electron correlation effects in the spin-dependent electronic structure of ferromagnetic bcc Fe(110) and hcp Co(0001) is investigated by means of spin- and angle-resolved photoemission spectroscopy. The experimental results are compared to theoretical calculations within the three-body scattering approximation and within the dynamical mean-field theory, together with one-step model calculations of the photoemission process. From this comparison it is demonstrated that the present state of the art many-body calculations, although improving the description of correlation effects in Fe and Co, give too small mass renormalizations and scattering rates thus demanding more refined many-body theories including nonlocal fluctuations. In the second part, it is shown in detail monitoring by photoelectron spectroscopy how graphene can be grown by chemical vapour deposition on the transition-metal surfaces Ni(111) and Co(0001) and intercalated by a monoatomic layer of Au. For both systems, a linear E(k) dispersion of massless Dirac fermions is observed in the graphene pi-band in the vicinity of the Fermi energy. Spin-resolved photoemission from the graphene pi-band shows that the ferromagnetic polarization of graphene/Ni(111) and graphene/Co(0001) is negligible and that graphene on Ni(111) is after intercalation of Au spin-orbit split by the Rashba effect. In the last part, a time-resolved x-ray magnetic circular dichroic-photoelectron emission microscopy study of a permalloy platelet comprising three cross-tie domain walls is presented. It is shown how a fast picosecond magnetic response in the precessional motion of the magnetization can be induced by means of a laser-excited photoswitch. From a comparision to micromagnetic calculations it is demonstrated that the relatively high precessional frequency observed in the experiments is directly linked to the nature of the vortex/antivortex dynamics and its response to the magnetic perturbation. This includes the time-dependent reversal of the vortex core polarization, a process which is beyond the limit of detection in the present experiments.}, language = {en} } @phdthesis{Fang2010, author = {Fang, Peng}, title = {Preparation and investigation of polymer-foam films and polymer-layer systems for ferroelectrets}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-48412}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Piezoelectric materials are very useful for applications in sensors and actuators. In addition to traditional ferroelectric ceramics and ferroelectric polymers, ferroelectrets have recently become a new group of piezoelectrics. Ferroelectrets are functional polymer systems for electromechanical transduction, with elastically heterogeneous cellular structures and internal quasi-permanent dipole moments. The piezoelectricity of ferroelectrets stems from linear changes of the dipole moments in response to external mechanical or electrical stress. Over the past two decades, polypropylene (PP) foams have been investigated with the aim of ferroelectret applications, and some products are already on the market. PP-foam ferroelectrets may exhibit piezoelectric d33 coefficients of 600 pC/N and more. Their operating temperature can, however, not be much higher than 60 °C. Recently developed polyethylene-terephthalate (PET) and cyclo-olefin copolymer (COC) foam ferroelectrets show slightly better d33 thermal stabilities, but usually at the price of smaller d33 values. Therefore, the main aim of this work is the development of new thermally stable ferroelectrets with appreciable piezoelectricity. Physical foaming is a promising technique for generating polymer foams from solid films without any pollution or impurity. Supercritical carbon dioxide (CO2) or nitrogen (N2) are usually employed as foaming agents due to their good solubility in several polymers. Polyethylene propylene (PEN) is a polyester with slightly better properties than PET. A "voiding + inflation + stretching" process has been specifically developed to prepare PEN foams. Solid PEN films are saturated with supercritical CO2 at high pressure and then thermally voided at high temperatures. Controlled inflation (Gas-Diffusion Expansion or GDE) is applied in order to adjust the void dimensions. Additional biaxial stretching decreases the void heights, since it is known lens-shaped voids lead to lower elastic moduli and therefore also to stronger piezoelectricity. Both, contact and corona charging are suitable for the electric charging of PEN foams. The light emission from the dielectric-barrier discharges (DBDs) can be clearly observed. Corona charging in a gas of high dielectric strength such as sulfur hexafluoride (SF6) results in higher gas-breakdown strength in the voids and therefore increases the piezoelectricity. PEN foams can exhibit piezoelectric d33 coefficients as high as 500 pC/N. Dielectric-resonance spectra show elastic moduli c33 of 1 - 12 MPa, anti-resonance frequencies of 0.2 - 0.8 MHz, and electromechanical coupling factors of 0.016 - 0.069. As expected, it is found that PEN foams show better thermal stability than PP and PET. Samples charged at room temperature can be utilized up to 80 - 100 °C. Annealing after charging or charging at elevated temperatures may improve thermal stabilities. Samples charged at suitable elevated temperatures show working temperatures as high as 110 - 120 °C. Acoustic measurements at frequencies of 2 Hz - 20 kHz show that PEN foams can be well applied in this frequency range. Fluorinated ethylene-propylene (FEP) copolymers are fluoropolymers with very good physical, chemical and electrical properties. The charge-storage ability of solid FEP films can be significantly improved by adding boron nitride (BN) filler particles. FEP foams are prepared by means of a one-step procedure consisting of CO2 saturation and subsequent in-situ high-temperature voiding. Piezoelectric d33 coefficients up to 40 pC/N are measured on such FEP foams. Mechanical fatigue tests show that the as-prepared PEN and FEP foams are mechanically stable for long periods of time. Although polymer-foam ferroelectrets have a high application potential, their piezoelectric properties strongly depend on the cellular morphology, i.e. on size, shape, and distribution of the voids. On the other hand, controlled preparation of optimized cellular structures is still a technical challenge. Consequently, new ferroelectrets based on polymer-layer system (sandwiches) have been prepared from FEP. By sandwiching an FEP mesh between two solid FEP films and fusing the polymer system with a laser beam, a well-designed uniform macroscopic cellular structure can be formed. Dielectric resonance spectroscopy reveals piezoelectric d33 coefficients as high as 350 pC/N, elastic moduli of about 0.3 MPa, anti-resonance frequencies of about 30 kHz, and electromechanical coupling factors of about 0.05. Samples charged at elevated temperatures show better thermal stabilities than those charged at room temperature, and the higher the charging temperature, the better is the stability. After proper charging at 140 °C, the working temperatures can be as high as 110 - 120 °C. Acoustic measurements at frequencies of 200 Hz - 20 kHz indicate that the FEP layer systems are suitable for applications at least in this range.}, language = {en} } @phdthesis{Wu2010, author = {Wu, Ye}, title = {Nonlinear dynamics in complex networks and modeling human dynamics}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-47358}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {Durch große Datenmengen k{\"o}nnen die Forscher die Eigenschaften komplexer Systeme untersuchen, z.B. komplexe Netzwerk und die Dynamik des menschlichen Verhaltens. Eine große Anzahl an Systemen werden als große und komplexe Netzwerke dargestellt, z.B. das Internet, Stromnetze, Wirtschaftssysteme. Immer mehr Forscher haben großes Interesse an der Dynamik des komplexen Netzwerks. Diese Arbeit besteht aus den folgenden drei Teilen. Der erste Teil ist ein einfacher dynamischer Optimierungs-Kopplungs-Mechanismus, aber sehr wirksam. Durch den Mechanismus kann synchronisation in komplexen Netzwerken mit und ohne Zeitverz{\"o}gerung realisiert, und die F{\"a}higkeit der Synchronisation von small-world und scale-free Netze verbessert werden. Im zweiten Teil geht um die Verst{\"a}rkung der Robustheit der scale-free Netze im Zusammenhang mit der Gemeinden-Struktur. Einige Reaktionsmuster und topologische Gemeinden sind einheitlich. Die Ergebnisse zeigen einen neuen Aspekt der Beziehung zwischen den Funktionen und der Netzwerk-Topologie von komplexen Netzwerken. Im dritten Teil welche eine wichtige Rolle in komplexen Netzwerken spielt, wird die Verhaltens-Dynamik der menschliche Mitteilung durch Daten- und Modellanalysierung erforscht, dann entsteht ein neues Mitteilungsmodell. Mit Hilfe von einem Interaktion priority-Queue Model kann das neue Modell erkl{\"a}rt werden. Mit Hilfe des Models k{\"o}nnen viele praktische Interaktions-Systeme erkl{\"a}rt werden, z.B. E-Mail und Briefe (oder Post). Mit Hilfe meiner Untersuchung kann man menschliches Verhalten auf der Individuums- und Netzwerkebene neu kennenlernen. Im vierter Teil kann ich nachweisen, dass menschliches Kommentar-Verhalten in on-line Sozialsystemen, eine andere Art der Interaktionsdynamik von Mensch non-Poisson ist und dieses am Modell erkl{\"a}ren. Mit Hilfe der non-Poisson Prozesse kann man das pers{\"o}nliche Anziehungskraft-Modell besser verstehen. Die Ergebnisse sind hilfreich zum Kennenlernen des Musters des menschlichen Verhaltens in on-line Gesellschaften und der Entwicklung von {\"o}ffentlicher Meinung nicht nur in der virtuellen Gesellschaftn sondern auch in der Realgesellschaft. Am Ende geht es um eine Prognose von menschlicher Dynamik und komplexen Netzwerken.}, language = {en} } @phdthesis{Stoeckle2010, author = {St{\"o}ckle, Silke}, title = {Thin liquid films with nanoparticles and rod-like ions as models for nanofluidics}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-46370}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {With the rise of nanotechnology in the last decade, nanofluidics has been established as a research field and gained increased interest in science and industry. Natural aqueous nanofluidic systems are very complex, there is often a predominance of liquid interfaces or the fluid contains charged or differently shaped colloids. The effects, promoted by these additives, are far from being completely understood and interesting questions arise with regards to the confinement of such complex fluidic systems. A systematic study of nanofluidic processes requires designing suitable experimental model nano - channels with required characteristics. The present work employed thin liquid films (TLFs) as experimental models. They have proven to be useful experimental tools because of their simple geometry, reproducible preparation, and controllable liquid interfaces. The thickness of the channels can be adjusted easily by the concentration of electrolyte in the film forming solution. This way, channel dimensions from 5 - 100 nm are possible, a high flexibility for an experimental system. TLFs have liquid IFs of different charge and properties and they offer the possibility to confine differently shaped ions and molecules to very small spaces, or to subject them to controlled forces. This makes the foam films a unique "device" available to obtain information about fluidic systems in nanometer dimensions. The main goal of this thesis was to study nanofluidic processes using TLFs as models, or tools, and to subtract information about natural systems plus deepen the understanding on physical chemical conditions. The presented work showed that foam films can be used as experimental models to understand the behavior of liquids in nano - sized confinement. In the first part of the thesis, we studied the process of thinning of thin liquid films stabilized with the non - ionic surfactant n - dodecyl - β - maltoside (β - C₁₂G₂) with primary interest in interfacial diffusion processes during the thinning process dependent on surfactant concentration 64. The surfactant concentration in the film forming solutions was varied at constant electrolyte (NaCl) concentration. The velocity of thinning was analyzed combining previously developed theoretical approaches. Qualitative information about the mobility of the surfactant molecules at the film surfaces was obtained. We found that above a certain limiting surfactant concentration the film surfaces were completely immobile and they behaved as non - deformable, which decelerated the thinning process. This follows the predictions for Reynolds flow of liquid between two non - deformable disks. In the second part of the thesis, we designed a TLF nanofluidic system containing rod - like multivalent ions and compared this system to films containing monovalent ions. We presented first results which recognized for the first time the existence of an additional attractive force in the foam films based on the electrostatic interaction between rod - like ions and oppositely charged surfaces. We may speculate that this is an ion bridging component of the disjoining pressure. The results show that for films prepared in presence of spermidine the transformation of the thicker CF to the thinnest NBF is more probable as films prepared with NaCl at similar conditions of electrostatic interaction. This effect is not a result of specific adsorption of any of the ions at the fluid surfaces and it does not lead to any changes in the equilibrium properties of the CF and NBF. Our hypothesis was proven using the trivalent ion Y3+ which does not show ion bridging. The experimental results are compared to theoretical predictions and a quantitative agreement on the system's energy gain for the change from CF to NBF could be obtained. In the third part of the work, the behavior of nanoparticles in confinement was investigated with respect to their impact on the fluid flow velocity. The particles altered the flow velocity by an unexpected high amount, so that the resulting changes in the dynamic viscosity could not be explained by a realistic change of the fluid viscosity. Only aggregation, flocculation and plug formation can explain the experimental results. The particle systems in the presented thesis had a great impact on the film interfaces due to the stabilizer molecules present in the bulk solution. Finally, the location of the particles with respect to their lateral and vertical arrangement in the film was studied with advanced reflectivity and scattering methods. Neutron Reflectometry studies were performed to investigate the location of nanoparticles in the TLF perpendicular to the IF. For the first time, we study TLFs using grazing incidence small angle X - ray scattering (GISAXS), which is a technique sensitive to the lateral arrangement of particles in confined volumes. This work provides preliminary data on a lateral ordering of particles in the film.}, language = {en} } @phdthesis{Penisson2010, author = {P{\´e}nisson, Sophie}, title = {Conditional limit theorems for multitype branching processes and illustration in epidemiological risk analysis}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-45307}, school = {Universit{\"a}t Potsdam}, year = {2010}, abstract = {This thesis is concerned with the issue of extinction of populations composed of different types of individuals, and their behavior before extinction and in case of a very late extinction. We approach this question firstly from a strictly probabilistic viewpoint, and secondly from the standpoint of risk analysis related to the extinction of a particular model of population dynamics. In this context we propose several statistical tools. The population size is modeled by a branching process, which is either a continuous-time multitype Bienaym{\´e}-Galton-Watson process (BGWc), or its continuous-state counterpart, the multitype Feller diffusion process. We are interested in different kinds of conditioning on non-extinction, and in the associated equilibrium states. These ways of conditioning have been widely studied in the monotype case. However the literature on multitype processes is much less extensive, and there is no systematic work establishing connections between the results for BGWc processes and those for Feller diffusion processes. In the first part of this thesis, we investigate the behavior of the population before its extinction by conditioning the associated branching process X_t on non-extinction (X_t≠0), or more generally on non-extinction in a near future 0≤θ<∞ (X_{t+θ}≠0), and by letting t tend to infinity. We prove the result, new in the multitype framework and for θ>0, that this limit exists and is non-degenerate. This reflects a stationary behavior for the dynamics of the population conditioned on non-extinction, and provides a generalization of the so-called Yaglom limit, corresponding to the case θ=0. In a second step we study the behavior of the population in case of a very late extinction, obtained as the limit when θ tends to infinity of the process conditioned by X_{t+θ}≠0. The resulting conditioned process is a known object in the monotype case (sometimes referred to as Q-process), and has also been studied when X_t is a multitype Feller diffusion process. We investigate the not yet considered case where X_t is a multitype BGWc process and prove the existence of the associated Q-process. In addition, we examine its properties, including the asymptotic ones, and propose several interpretations of the process. Finally, we are interested in interchanging the limits in t and θ, as well as in the not yet studied commutativity of these limits with respect to the high-density-type relationship between BGWc processes and Feller processes. We prove an original and exhaustive list of all possible exchanges of limit (long-time limit in t, increasing delay of extinction θ, diffusion limit). The second part of this work is devoted to the risk analysis related both to the extinction of a population and to its very late extinction. We consider a branching population model (arising notably in the epidemiological context) for which a parameter related to the first moments of the offspring distribution is unknown. We build several estimators adapted to different stages of evolution of the population (phase growth, decay phase, and decay phase when extinction is expected very late), and prove moreover their asymptotic properties (consistency, normality). In particular, we build a least squares estimator adapted to the Q-process, allowing a prediction of the population development in the case of a very late extinction. This would correspond to the best or to the worst-case scenario, depending on whether the population is threatened or invasive. These tools enable us to study the extinction phase of the Bovine Spongiform Encephalopathy epidemic in Great Britain, for which we estimate the infection parameter corresponding to a possible source of horizontal infection persisting after the removal in 1988 of the major route of infection (meat and bone meal). This allows us to predict the evolution of the spread of the disease, including the year of extinction, the number of future cases and the number of infected animals. In particular, we produce a very fine analysis of the evolution of the epidemic in the unlikely event of a very late extinction.}, language = {en} }