@misc{LadwigZhouXuetal.2018, author = {Ladwig, Simon and Zhou, Zien and Xu, Ying and Wang, Xia and Chow, Clara K. and Werheid, Katja and Hackett, Maree L.}, title = {Comparison of treatment rates of depression after stroke versus myocardial infarction}, series = {Psychosomatic medicine}, volume = {80}, journal = {Psychosomatic medicine}, number = {8}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {0033-3174}, doi = {10.1097/PSY.0000000000000632}, pages = {754 -- 763}, year = {2018}, abstract = {Objective Depression after stroke and myocardial infarction (MI) is common but often assumed to be undertreated without reliable evidence being available. Thus, we aimed to determine treatment rates and investigate the application of guidelines in these conditions. Methods Databases MEDLINE, EMBASE, PsycInfo, Web of Science, CINAHL, and Scopus were systematically searched without language restriction from inception to June 30, 2017. Prospective observational studies with consecutive recruitment reporting any antidepressant treatment in adults with depression after stroke or MI were included. Random-effects models were used to calculate pooled estimates of treatment rates. Results Fifty-five studies reported 32 stroke cohorts (n = 8938; pooled frequency of depression = 34\%, 95\% confidence interval [CI] = 29\%-38\%) and 17 MI cohorts (n = 10,767; pooled frequency of depression = 24\%, 95\% CI = 20\%-28\%). In 29 stroke cohorts, 24\% (95\% CI = 20\%-27\%) of 2280 depressed people used antidepressant medication. In 15 MI cohorts, 14\% (95\% CI = 8\%-19\%) of 2381 depressed people used antidepressant medication indicating a lower treatment rate than in stroke. Two studies reported use of psychosocial interventions, indicating that less than 10\% of participants were treated. Conclusions Despite the high frequency of depression after stroke and MI and the existence of efficacious treatment strategies, people often remain untreated. Innovative strategies are needed to increase the use of effective antidepressive interventions in patients with cardiovascular disease.}, language = {en} } @article{LadwigVolzWerheid2018, author = {Ladwig, Simon and Volz, Matthias and Werheid, Katja}, title = {Depression ist weiblich - auch nach Schlaganfall?}, series = {Zeitschrift f{\"u}r Neuropsychologie}, volume = {29}, journal = {Zeitschrift f{\"u}r Neuropsychologie}, number = {3}, publisher = {Hogrefe}, address = {Bern}, issn = {1016-264X}, doi = {10.1024/1016-264X/a000225}, pages = {141 -- 147}, year = {2018}, abstract = {W{\"a}hrend Frauen in der Allgemeinbev{\"o}lkerung ein h{\"o}heres Depressionsrisiko aufweisen als M{\"a}nner, ist die Forschungslage zu Geschlechterunterschieden nach Schlaganfall heterogen. Die vorliegende L{\"a}ngsschnittstudie untersucht Geschlechterunterschiede in der H{\"a}ufigkeit von depressiven St{\"o}rungen und Symptomen nach Schlaganfall. An zwei deutschen Rehabilitationszentren wurden N = 174 Schlaganfallpatienten und -patientinnen1 (n = 72 weiblich) rekrutiert und etablierte Risikofaktoren erfasst. Nacherhebungen fanden nach acht und 15 Monaten statt. Depressive St{\"o}rungen und Symptome waren h{\"a}ufiger bei Frauen (48.2 \%) als bei M{\"a}nnern (28.3 \%) w{\"a}hrend der station{\"a}ren Rehabilitation, jedoch nicht in den Folgeuntersuchungen. Etablierte Risikofaktoren beeinflussten geschlechtsunabh{\"a}ngig die Auspr{\"a}gung depressiver Symptomatik. In {\"U}bereinstimmung mit aktuellen Meta-Analysen zeigten sich keine dauerhaften Geschlechterunterschiede bei Depression nach Schlaganfall. In der klinischen Praxis sollte die Affektlage von Schlaganfallpatienten geschlechtsunabh{\"a}ngig betrachtet werden.}, language = {de} }