@article{RackwitzRankovićMilosavljevićetal.2017, author = {Rackwitz, Jenny and Ranković, Miloš Lj. and Milosavljević, Aleksandar R. and Bald, Ilko}, title = {A novel setup for the determination of absolute cross sections for low-energy electron induced strand breaks in oligonucleotides}, series = {The European physical journal : D, Atomic, molecular, optical and plasma physics}, volume = {71}, journal = {The European physical journal : D, Atomic, molecular, optical and plasma physics}, publisher = {Springer}, address = {New York}, issn = {1434-6060}, doi = {10.1140/epjd/e2016-70608-4}, pages = {9}, year = {2017}, abstract = {Low-energy electrons (LEEs) play an important role in DNA radiation damage. Here we present a method to quantify LEE induced strand breakage in well-defined oligonucleotide single strands in terms of absolute cross sections. An LEE irradiation setup covering electron energies <500 eV is constructed and optimized to irradiate DNA origami triangles carrying well-defined oligonucleotide target strands. Measurements are presented for 10.0 and 5.5 eV for different oligonucleotide targets. The determination of absolute strand break cross sections is performed by atomic force microscopy analysis. An accurate fluence determination ensures small margins of error of the determined absolute single strand break cross sections sigma SSB. In this way, the influence of sequence modification with the radiosensitive 5-Fluorouracil (U-5F) is studied using an absolute and relative data analysis. We demonstrate an increase in the strand break yields of U-5F containing oligonucleotides by a factor of 1.5 to 1.6 compared with non-modified oligonucleotide sequences when irradiated with 10 eV electrons.}, language = {en} } @article{ListekHoenowGossenetal.2020, author = {Listek, Martin and H{\"o}now, Anja and Gossen, Manfred and Hanack, Katja}, title = {A novel selection strategy for antibody producing hybridoma cells based on a new transgenic fusion cell line}, series = {Scientific Reports}, volume = {10}, journal = {Scientific Reports}, publisher = {Macmillan Publishers Limited, part of Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-020-58571-w}, pages = {12}, year = {2020}, abstract = {The use of monoclonal antibodies is ubiquitous in science and biomedicine but the generation and validation process of antibodies is nevertheless complicated and time-consuming. To address these issues we developed a novel selective technology based on an artificial cell surface construct by which secreted antibodies were connected to the corresponding hybridoma cell when they possess the desired antigen-specificity. Further the system enables the selection of desired isotypes and the screening for potential cross-reactivities in the same context. For the design of the construct we combined the transmembrane domain of the EGF-receptor with a hemagglutinin epitope and a biotin acceptor peptide and performed a transposon-mediated transfection of myeloma cell lines. The stably transfected myeloma cell line was used for the generation of hybridoma cells and an antigen- and isotype-specific screening method was established. The system has been validated for globular protein antigens as well as for haptens and enables a fast and early stage selection and validation of monoclonal antibodies in one step.}, language = {en} } @article{VaidyaSchmidtRakowskietal.2021, author = {Vaidya, Shrijana and Schmidt, Marten and Rakowski, Peter and Bonk, Norbert and Verch, Gernot and Augustin, J{\"u}rgen and Sommer, Michael and Hoffmann, Mathias}, title = {A novel robotic chamber system allowing to accurately and precisely determining spatio-temporal CO2 flux dynamics of heterogeneous croplands}, series = {Agricultural and forest meteorology}, volume = {296}, journal = {Agricultural and forest meteorology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0168-1923}, doi = {10.1016/j.agrformet.2020.108206}, pages = {9}, year = {2021}, abstract = {The precise and accurate assessment of carbon dioxide (CO2) exchange is crucial to identify terrestrial carbon (C) sources and sinks and for evaluating their role within the global C budget. The substantial uncertainty in disentangling the management and soil impact on measured CO2 fluxes are largely ignored especially in cropland. The reasons for this lies in the limitation of the widely used eddy covariance as well as manual and automatic chamber systems, which either account for short-term temporal variability or small-scale spatial heterogeneity, but barely both. To address this issue, we developed a novel robotic chamber system allowing for dozens of spatial measurement repetitions, thus enabling CO2 exchange measurements in a sufficient temporal and high small-scale spatial resolution. The system was tested from 08th July to 09th September 2019 at a heterogeneous field (100 m x 16 m), located within the hummocky ground moraine landscape of northeastern Germany (CarboZALF-D). The field is foreseen for a longer-term block trial manipulation experiment extending over three erosion induced soil types and was covered with spring barley. Measured fluxes of nighttime ecosystem respiration (R-eco) and daytime net ecosystem exchange (NEE) showed distinct temporal patterns influenced by crop phenology, weather conditions and management practices. Similarly, we found clear small-scale spatial differences in cumulated (gap-filled) R-eco, gross primary productivity (GPP) and NEE fluxes affected by the three distinct soil types. Additionally, spatial patterns induced by former management practices and characterized by differences in soil pH and nutrition status (P and K) were also revealed between plots within each of the three soil types, which allowed compensating for prior to the foreseen block trial manipulation experiment. The results underline the great potential of the novel robotic chamber system, which not only detects short-term temporal CO2 flux dynamics but also reflects the impact of small-scale spatial heterogeneity.}, language = {en} } @article{DrexlerGrotjahnKleinpeteretal.1999, author = {Drexler, Hans-Joachim and Grotjahn, Manuela and Kleinpeter, Erich and Holdt, Hans-J{\"u}rgen}, title = {A novel polymeric disilver(I) complex containing both macrocyclic- and linear-coordinate silver(I) centres : [Ag-2(mn-15S(2)O(3))](infinity)(ClO4)(2 infinity) (mn-15S(2)O(3) = maleonitrile-dithia[15]crown-5)}, year = {1999}, language = {en} } @article{SchaalKotzurDekowskietal.2009, author = {Schaal, Janina and Kotzur, Nico and Dekowski, Brigitte and Quilitz, Jana and Klimakow, Maria and Wessig, Pablo and Hagen, Volker}, title = {A novel photorearrangement of (coumarin-4-yl)methyl phenyl ethers}, issn = {1010-6030}, doi = {10.1016/j.jphotochem.2009.09.012}, year = {2009}, abstract = {In the present study, we describe synthesis and photochemical behaviour of the coumarinylmethyl phenyl ethers 1 and 6-10. Irradiation of the compounds in polar solvents leads to o-, p- and m-hydroxybenzyl substituted coumarins as main products. A side reaction is the photosolvolysis of the ethers that gives the (coumarin-4-yl)methyl alcohol and the corresponding phenol. Detailed studies of the quantum yields and product distributions upon irradiation of 6 as a function of the solvents are indicative of a dominant role of an ionic pathway in photochemical conversions. The found photochemical rearrangement is a useful tool for the preparation of hydroxylated 4-benzylcoumarins. A series of such compounds have been synthesised.}, language = {en} } @article{KagelBierFrohmeetal.2019, author = {Kagel, Heike and Bier, Frank Fabian and Frohme, Marcus and Gl{\"o}kler, J{\"o}rn F.}, title = {A Novel Optical Method To Reversibly Control Enzymatic Activity Based On Photoacids}, series = {Scientific reports}, volume = {9}, journal = {Scientific reports}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-019-50867-w}, pages = {6}, year = {2019}, abstract = {Most biochemical reactions depend on the pH value of the aqueous environment and some are strongly favoured to occur in an acidic environment. A non-invasive control of pH to tightly regulate such reactions with defined start and end points is a highly desirable feature in certain applications, but has proven difficult to achieve so far. We report a novel optical approach to reversibly control a typical biochemical reaction by changing the pH and using acid phosphatase as a model enzyme. The reversible photoacid G-acid functions as a proton donor, changing the pH rapidly and reversibly by using high power UV LEDs as an illumination source in our experimental setup. The reaction can be tightly controlled by simply switching the light on and off and should be applicable to a wide range of other enzymatic reactions, thus enabling miniaturization and parallelization through non-invasive optical means.}, language = {en} } @article{GajovicWarsinkeScheller1995, author = {Gajovic, Nenad and Warsinke, Axel and Scheller, Frieder W.}, title = {A novel multienzyme electrode for the determination of citrate}, year = {1995}, language = {en} } @article{LuetkecosmannWarsinkeTschoepeetal.2017, author = {L{\"u}tkecosmann, Steffi and Warsinke, Axel and Tsch{\"o}pe, Winfried and Eichler, R{\"u}diger and Hanack, Katja}, title = {A novel monoclonal antibody suitable for the detection of leukotriene B4}, series = {Biochemical and biophysical research communications}, volume = {482}, journal = {Biochemical and biophysical research communications}, number = {4}, publisher = {Elsevier}, address = {San Diego}, issn = {0006-291X}, doi = {10.1016/j.bbrc.2016.11.157}, pages = {1054 -- 1059}, year = {2017}, abstract = {Leukotriene B4 as an inflammatory mediator is an important biomarker for different respiratory diseases like asthma, chronic obstructive pulmonary disease or cystic lung fibrosis. Therefore the detection of LTB4 is helpful in the diagnosis of these pulmonary diseases. However, until now its determination in exhaled breath condensates suffers from problems of accuracy. Reasons for that could be improper sample collection and preparation methods of condensates and the lack of consistently assay specificity and reproducibility of the used immunoassay detection system. In this study we describe the development and the characterization of a specific monoclonal antibody (S27BC6) against LTB4, its use as molecular recognition element for the development of an enzyme-linked immunoassay to detect LTB4 and discuss possible future diagnostic applications.}, language = {en} } @article{HahnewaldLeimkuehlerVilasecaetal.2006, author = {Hahnewald, Rita and Leimk{\"u}hler, Silke and Vilaseca, Antonia and Acquaviva-Bourdain, Cecile and Lenz, Ulrike and Reiss, Jochen}, title = {A novel MOCS2 mutation reveals coordinated expression of the small and large subunit of molybdopterin synthase}, series = {Molecular genetics and metabolism}, volume = {89}, journal = {Molecular genetics and metabolism}, number = {3}, publisher = {Elsevier}, address = {San Diego}, issn = {1096-7192}, doi = {10.1016/j.ymgme.2006.04.008}, pages = {210 -- 213}, year = {2006}, abstract = {The small and large subunits of molybdopterin (MPT) synthase (MOCS2A and MOCS2B), are both encoded by the MOCS2 gene in overlapping and shifted open reading frames (ORFs), which is a highly unusual structure for eukaryotes. Theoretical analysis of genomic sequences suggested that the expression of these overlapping ORFs is facilitated by the use of alternate first exons leading to alternative transcripts. Here, we confirm the existence of these overlapping transcripts experimentally. Further, we identified a deletion in a molybdenum cofactor deficient patient, which removes the start codon for the small subunit (MOCS2A). We observed undisturbed production of both transcripts, while Western blot analysis demonstrated that MOCS2B, the large subunit, is unstable in the absence of MOCS2A. This reveals new insights into the expression of this evolutionary ancient anabolic system.}, language = {en} } @article{LehrPoeschkeLewandowskietal.2015, author = {Lehr, C. and P{\"o}schke, Franziska and Lewandowski, J{\"o}rg and Lischeid, Gunnar}, title = {A novel method to evaluate the effect of a stream restoration on the spatial pattern of hydraulic connection of stream and groundwater}, series = {Journal of hydrology}, volume = {527}, journal = {Journal of hydrology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0022-1694}, doi = {10.1016/j.jhydrol.2015.04.075}, pages = {394 -- 401}, year = {2015}, abstract = {Stream restoration aims at an enhancement of ecological habitats, an increase of water retention within a landscape and sometimes even at an improvement of biogeochemical functions of lotic ecosystems. For the latter, good exchange between groundwater and stream water is often considered to be of major importance. In this study hydraulic connectivity between river and aquifer was investigated for a four years period, covering the restoration of an old oxbow after the second year. The oxbow became reconnected to the stream and the clogging layer in the oxbow was excavated. We expected increasing hydraulic connectivity between oxbow and aquifer after restoration of the stream, and decreasing hydraulic connectivity for the former shortcut due to increased clogging. To test that hypothesis, the spatial and temporal characteristics of the coupled groundwater-stream water system before and after the restoration were analysed by principal component analyses of time series of groundwater heads and stream water levels. The first component depicted between 53\% and 70\% of the total variance in the dataset for the different years. It captured the propagation of the pressure signal induced by stream water level fluctuations throughout the adjacent aquifer. Thus it could be used as a measure of hydraulic connectivity between stream and aquifer. During the first year, the impact of stream water level fluctuations decreased with distance from the regulated river (shortcut), whereas the hydraulic connection of the oxbow to the adjacent aquifer was very low. After restoration of the stream we observed a slight but not significant increase of hydraulic connectivity in the oxbow in the second year after restoration, but no change for the former shortcut. There is some evidence that the pattern of hydraulic connectivity at the study site is by far more determined by the natural heterogeneity of hydraulic conductivities of the floodplain sediments and the initial construction of the shortcut rather than by the clogging layer in the oxbow. (C) 2015 The Authors. Published by Elsevier B.V.}, language = {en} } @article{FernandezPalominoHattermannKrysanovaetal.2022, author = {Fernandez-Palomino, Carlos Antonio and Hattermann, Fred and Krysanova, Valentina and Lobanova, Anastasia and Vega-Jacome, Fiorella and Lavado, Waldo and Santini, William and Aybar, Cesar and Bronstert, Axel}, title = {A novel high-resolution gridded precipitation dataset for peruvian and ecuadorian watersheds}, series = {Journal of hydrometeorology}, volume = {23}, journal = {Journal of hydrometeorology}, number = {3}, publisher = {American Meteorological Soc.}, address = {Boston}, issn = {1525-755X}, doi = {10.1175/JHM-D-20-0285.1}, pages = {309 -- 336}, year = {2022}, abstract = {A novel approach for estimating precipitation patterns is developed here and applied to generate a new hydrologically corrected daily precipitation dataset, called RAIN4PE (Rain for Peru and Ecuador), at 0.1 degrees spatial resolution for the period 1981-2015 covering Peru and Ecuador. It is based on the application of 1) the random forest method to merge multisource precipitation estimates (gauge, satellite, and reanalysis) with terrain elevation, and 2) observed and modeled streamflow data to first detect biases and second further adjust gridded precipitation by inversely applying the simulated results of the ecohydrological model SWAT (Soil and Water Assessment Tool). Hydrological results using RAIN4PE as input for the Peruvian and Ecuadorian catchments were compared against the ones when feeding other uncorrected (CHIRP and ERA5) and gauge-corrected (CHIRPS, MSWEP, and PISCO) precipitation datasets into the model. For that, SWAT was calibrated and validated at 72 river sections for each dataset using a range of performance metrics, including hydrograph goodness of fit and flow duration curve signatures. Results showed that gauge-corrected precipitation datasets outperformed uncorrected ones for streamflow simulation. However, CHIRPS, MSWEP, and PISCO showed limitations for streamflow simulation in several catchments draining into the Pacific Ocean and the Amazon River. RAIN4PE provided the best overall performance for streamflow simulation, including flow variability (low, high, and peak flows) and water budget closure. The overall good performance of RAIN4PE as input for hydrological modeling provides a valuable criterion of its applicability for robust countrywide hydrometeorological applications, including hydroclimatic extremes such as droughts and floods. Significance StatementWe developed a novel precipitation dataset RAIN4PE for Peru and Ecuador by merging multisource precipitation data (satellite, reanalysis, and ground-based precipitation) with terrain elevation using the random forest method. Furthermore, RAIN4PE was hydrologically corrected using streamflow data in watersheds with precipitation underestimation through reverse hydrology. The results of a comprehensive hydrological evaluation showed that RAIN4PE outperformed state-of-the-art precipitation datasets such as CHIRP, ERA5, CHIRPS, MSWEP, and PISCO in terms of daily and monthly streamflow simulations, including extremely low and high flows in almost all Peruvian and Ecuadorian catchments. This underlines the suitability of RAIN4PE for hydrometeorological applications in this region. Furthermore, our approach for the generation of RAIN4PE can be used in other data-scarce regions.}, language = {en} } @article{ThomasKleinpeter2005, author = {Thomas, Steffen and Kleinpeter, Erich}, title = {A novel empirical approach for the structure elucidation of disilanes by empirical estimation of their Si-29 chemical shifts}, issn = {0022-2860}, year = {2005}, abstract = {In C-13 NMR spectroscopy, there are many empirical methods for fast and exact computation of C-13 chemical shifts; comparable procedures for Si-29 NMR chemical shifts are not existing or are older than 20 years. On basis of the largest database of Si-29 chemical shifts available, along this paper a relatively simple procedure for the similarly exact calculation of the Si-29 chemical shifts of disilanes (average margin of error ca. 3.7 ppm) is given. (c) 2005 Elsevier B.V. All rights reserved}, language = {en} } @article{GostkowskaLeknerWallacherGrimmetal.2020, author = {Gostkowska-Lekner, Natalia Katarzyna and Wallacher, Dirk and Grimm, Nico and Habicht, Klaus and Hofmann, Tommy}, title = {A novel electrochemical anodization cell for the synthesis of mesoporous silicon}, series = {Review of scientific instruments : a monthly journal devoted to scientific instruments, apparatus, and techniques}, volume = {91}, journal = {Review of scientific instruments : a monthly journal devoted to scientific instruments, apparatus, and techniques}, number = {10}, publisher = {American Institute of Physics}, address = {Melville, NY}, issn = {0034-6748}, doi = {10.1063/5.0008536}, pages = {6}, year = {2020}, abstract = {A novel design of an electrochemical anodization cell dedicated to the synthesis of mesoporous, single-crystalline silicon is presented. First and foremost, the design principle follows user safety since electrochemical etching of silicon requires highly hazardous electrolytes based on hydrofluoric (HF) acid. The novel cell design allows for safe electrolyte handling prior, during, and post-etching. A peristaltic pump with HF-resistant fluoroelastomer tubing transfers electrolytes between dedicated reservoirs and the anodization cell. Due to the flexibility of the cell operation, different processing conditions can be realized providing a large parameter range for the attainable sample thickness, its porosity, and the mean pore size. Rapid etching on the order of several minutes to synthesize micrometer-thick porous silicon epilayers on bulk silicon is possible as well as long-time etching with continuous, controlled electrolyte flow for several days to prepare up to 1000 mu m thick self-supporting porous silicon membranes. A highly adaptable, LabVIEW((TM))-based control software allows for user-defined etching profiles.}, language = {en} } @article{KawanabeBlanchardSugiyamaetal.2006, author = {Kawanabe, Motoaki and Blanchard, Gilles and Sugiyama, Masashi and Spokoiny, Vladimir G. and M{\"u}ller, Klaus-Robert}, title = {A novel dimension reduction procedure for searching non-Gaussian subspaces}, issn = {0302-9743}, doi = {10.1007/11679363_19}, year = {2006}, abstract = {In this article, we consider high-dimensional data which contains a low-dimensional non-Gaussian structure contaminated with Gaussian noise and propose a new linear method to identify the non-Gaussian subspace. Our method NGCA (Non-Gaussian Component Analysis) is based on a very general semi-parametric framework and has a theoretical guarantee that the estimation error of finding the non-Gaussian components tends to zero at a parametric rate. NGCA can be used not only as preprocessing for ICA, but also for extracting and visualizing more general structures like clusters. A numerical study demonstrates the usefulness of our method}, language = {en} } @article{vanderValkKreinerMollerKooijmanetal.2015, author = {van der Valk, Ralf J. P. and Kreiner-Moller, Eskil and Kooijman, Marjolein N. and Guxens, Monica and Stergiakouli, Evangelia and Saaf, Annika and Bradfield, Jonathan P. and Geller, Frank and Hayes, M. Geoffrey and Cousminer, Diana L. and Koerner, Antje and Thiering, Elisabeth and Curtin, John A. and Myhre, Ronny and Huikari, Ville and Joro, Raimo and Kerkhof, Marjan and Warrington, Nicole M. and Pitkanen, Niina and Ntalla, Ioanna and Horikoshi, Momoko and Veijola, Riitta and Freathy, Rachel M. and Teo, Yik-Ying and Barton, Sheila J. and Evans, David M. and Kemp, John P. and St Pourcain, Beate and Ring, Susan M. and Smith, George Davey and Bergstrom, Anna and Kull, Inger and Hakonarson, Hakon and Mentch, Frank D. and Bisgaard, Hans and Chawes, Bo Lund Krogsgaard and Stokholm, Jakob and Waage, Johannes and Eriksen, Patrick and Sevelsted, Astrid and Melbye, Mads and van Duijn, Cornelia M. and Medina-Gomez, Carolina and Hofman, Albert and de Jongste, Johan C. and Taal, H. Rob and Uitterlinden, Andre G. and Armstrong, Loren L. and Eriksson, Johan and Palotie, Aarno and Bustamante, Mariona and Estivill, Xavier and Gonzalez, Juan R. and Llop, Sabrina and Kiess, Wieland and Mahajan, Anubha and Flexeder, Claudia and Tiesler, Carla M. T. and Murray, Clare S. and Simpson, Angela and Magnus, Per and Sengpiel, Verena and Hartikainen, Anna-Liisa and Keinanen-Kiukaanniemi, Sirkka and Lewin, Alexandra and Alves, Alexessander Da Silva Couto and Blakemore, Alexandra I. F. and Buxton, Jessica L. and Kaakinen, Marika and Rodriguez, Alina and Sebert, Sylvain and Vaarasmaki, Marja and Lakka, Timo and Lindi, Virpi and Gehring, Ulrike and Postma, Dirkje S. and Ang, Wei and Newnham, John P. and Lyytikainen, Leo-Pekka and Pahkala, Katja and Raitakari, Olli T. and Panoutsopoulou, Kalliope and Zeggini, Eleftheria and Boomsma, Dorret I. and Groen-Blokhuis, Maria and Ilonen, Jorma and Franke, Lude and Hirschhorn, Joel N. and Pers, Tune H. and Liang, Liming and Huang, Jinyan and Hocher, Berthold and Knip, Mikael and Saw, Seang-Mei and Holloway, John W. and Melen, Erik and Grant, Struan F. A. and Feenstra, Bjarke and Lowe, William L. and Widen, Elisabeth and Sergeyev, Elena and Grallert, Harald and Custovic, Adnan and Jacobsson, Bo and Jarvelin, Marjo-Riitta and Atalay, Mustafa and Koppelman, Gerard H. and Pennell, Craig E. and Niinikoski, Harri and Dedoussis, George V. and Mccarthy, Mark I. and Frayling, Timothy M. and Sunyer, Jordi and Timpson, Nicholas J. and Rivadeneira, Fernando and Bonnelykke, Klaus and Jaddoe, Vincent W. V.}, title = {A novel common variant in DCST2 is associated with length in early life and height in adulthood}, series = {Human molecular genetics}, volume = {24}, journal = {Human molecular genetics}, number = {4}, publisher = {Oxford Univ. Press}, address = {Oxford}, organization = {Early Genetics Lifecourse, Genetic Invest ANthropometric, Early Growth Genetics EGG}, issn = {0964-6906}, doi = {10.1093/hmg/ddu510}, pages = {1155 -- 1168}, year = {2015}, abstract = {Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 x 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height (LCORL, PTCH1, GPR126 and HMGA2). The three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938 in DC-STAMP domain containing 2 (DCST2) genome-wide significantly associated with birth length in a joint analysis (Stages 1 + 2; beta = 0.046, SE = 0.008, P = 2.46 x 10(-8), explained variance = 0.05\%). Rs905938 was also associated with infant length (N = 28 228; P = 5.54 x 10(-4)) and adult height (N = 127 513; P = 1.45 x 10(-5)). DCST2 is a DC-STAMP-like protein family member and DC-STAMP is an osteoclast cell-fusion regulator. Polygenic scores based on 180 SNPs previously associated with human adult stature explained 0.13\% of variance in birth length. The same SNPs explained 2.95\% of the variance of infant length. Of the 180 known adult height loci, 11 were genome-wide significantly associated with infant length (SF3B4, LCORL, SPAG17, C6orf173, PTCH1, GDF5, ZNFX1, HHIP, ACAN, HLA locus and HMGA2). This study highlights that common variation in DCST2 influences variation in early growth and adult height.}, language = {en} } @article{WoutersenJardineGiovanniBogotaAngeletal.2018, author = {Woutersen, Amber and Jardine, Phillip E. and Giovanni Bogota-Angel, Raul and Zhang, Hong-Xiang and Silvestro, Daniele and Antonelli, Alexandre and Gogna, Elena and Erkens, Roy H. J. and Gosling, William D. and Dupont-Nivet, Guillaume and Hoorn, Carina}, title = {A novel approach to study the morphology and chemistry of pollen in a phylogenetic context, applied to the halophytic taxon Nitraria L.(Nitrariaceae)}, series = {PeerJ}, volume = {6}, journal = {PeerJ}, publisher = {PeerJ Inc.}, address = {London}, issn = {2167-8359}, doi = {10.7717/peerj.5055}, pages = {31}, year = {2018}, abstract = {Nitraria is a halophytic taxon (i.e., adapted to saline environments) that belongs to the plant family Nitrariaceae and is distributed from the Mediterranean, across Asia into the south-eastern tip of Australia. This taxon is thought to have originated in Asia during the Paleogene (66-23 Ma), alongside the proto-Paratethys epicontinental sea. The evolutionary history of Nitraria might hold important clues on the links between climatic and biotic evolution but limited taxonomic documentation of this taxon has thus far hindered this line of research. Here we investigate if the pollen morphology and the chemical composition of the pollen wall are informative of the evolutionary history of Nitraria and could explain if origination along the proto-Paratethys and dispersal to the Tibetan Plateau was simultaneous or a secondary process. To answer these questions, we applied a novel approach consisting of a combination of Fourier Transform Infrared spectroscopy (FTIR), to determine the chemical composition of the pollen wall, and pollen morphological analyses using Light Microscopy (LM) and Scanning Electron Microscopy (SEM). We analysed our data using ordinations (principal components analysis and non-metric multidimensional scaling), and directly mapped it on the Nitrariaceae phylogeny to produce a phylomorphospace and a phylochemospace. Our LM, SEM and FTIR analyses show clear morphological and chemical differences between the sister groups Peganum and Nitraria. Differences in the morphological and chemical characteristics of highland species (Nitraria schoberi, N. sphaerocarpa, N. sibirica and N. tangutorum) and lowland species (Nitraria billardierei and N. retusa) are very subtle, with phylogenetic history appearing to be a more important control on Nitraria pollen than local environmental conditions. Our approach shows a compelling consistency between the chemical and morphological characteristics of the eight studied Nitrariaceae species, and these traits are in agreement with the phylogenetic tree. Taken together, this demonstrates how novel methods for studying fossil pollen can facilitate the evolutionary investigation of living and extinct taxa, and the environments they represent.}, language = {en} } @article{GomezNavaGrossmannHintscheetal.2020, author = {G{\´o}mez-Nava, Luis and Grossmann, Robert and Hintsche, Marius and Beta, Carsten and Peruani, Fernando}, title = {A novel approach to chemotaxis}, series = {epl : a letters journal exploring the frontiers of physics}, volume = {130}, journal = {epl : a letters journal exploring the frontiers of physics}, number = {6}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0295-5075}, doi = {10.1209/0295-5075/130/68002}, pages = {7}, year = {2020}, abstract = {Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the clock depends on an external concentration field, e.g., a chemical substance. We demonstrate that these particles can detect concentration gradients and respond to them by moving up- or down-gradient depending on the clock design, albeit measurements of these fields are purely local in space and instantaneous in time. Altogether, our results open a new route in the study of directional navigation: we show that the use of a clock to control motility actions represents a generic and versatile toolbox to engineer behavioral responses to external cues, such as light, chemical, or temperature gradients.}, language = {en} } @article{Vicente2010, author = {Vicente, Luis}, title = {A note on the movement analysis of gapping}, issn = {0024-3892}, year = {2010}, language = {en} } @article{Zoeller2022, author = {Z{\"o}ller, Gert}, title = {A note on the estimation of the maximum possible earthquake magnitude based on extreme value theory for the Groningen Gas Field}, series = {The bulletin of the Seismological Society of America : BSSA}, volume = {112}, journal = {The bulletin of the Seismological Society of America : BSSA}, number = {4}, publisher = {Seismological Society of America}, address = {El Cerito, Calif.}, issn = {0037-1106}, doi = {10.1785/0120210307}, pages = {1825 -- 1831}, year = {2022}, abstract = {Extreme value statistics is a popular and frequently used tool to model the occurrence of large earthquakes. The problem of poor statistics arising from rare events is addressed by taking advantage of the validity of general statistical properties in asymptotic regimes. In this note, I argue that the use of extreme value statistics for the purpose of practically modeling the tail of the frequency-magnitude distribution of earthquakes can produce biased and thus misleading results because it is unknown to what degree the tail of the true distribution is sampled by data. Using synthetic data allows to quantify this bias in detail. The implicit assumption that the true M-max is close to the maximum observed magnitude M-max,M-observed restricts the class of the potential models a priori to those with M-max = M-max,M-observed + Delta M with an increment Delta M approximate to 0.5... 1.2. This corresponds to the simple heuristic method suggested by Wheeler (2009) and labeled :M-max equals M-obs plus an increment." The incomplete consideration of the entire model family for the frequency-magnitude distribution neglects, however, the scenario of a large so far unobserved earthquake.}, language = {en} } @article{Jansen1997, author = {Jansen, Wolfgang}, title = {A note on the determination of the type of communication areas}, year = {1997}, language = {en} } @article{HinzSchwarz2022, author = {Hinz, Michael and Schwarz, Michael}, title = {A note on Neumann problems on graphs}, series = {Positivity}, volume = {26}, journal = {Positivity}, number = {4}, publisher = {Springer}, address = {Dordrecht}, issn = {1385-1292}, doi = {10.1007/s11117-022-00930-0}, pages = {23}, year = {2022}, abstract = {We discuss Neumann problems for self-adjoint Laplacians on (possibly infinite) graphs. Under the assumption that the heat semigroup is ultracontractive we discuss the unique solvability for non-empty subgraphs with respect to the vertex boundary and provide analytic and probabilistic representations for Neumann solutions. A second result deals with Neumann problems on canonically compactifiable graphs with respect to the Royden boundary and provides conditions for unique solvability and analytic and probabilistic representations.}, language = {en} } @article{Andree2013, author = {Andree, Kai}, title = {A note on merger in mixed duopoly - Bertrand versus Cournot}, series = {Journal of economics}, volume = {108}, journal = {Journal of economics}, number = {3}, publisher = {Springer}, address = {Wien}, issn = {0931-8658}, doi = {10.1007/s00712-012-0280-x}, pages = {291 -- 298}, year = {2013}, abstract = {In this note we analyze the incentives to merge in a mixed duopoly if firms compete in prices or quantities. Our model framework mainly follows Barcena-Ruiz and Garzon (J Econ 80:27-42, 2003) who set up the model with quantity competition. We extend their analysis by analyzing the case of competition in prices. Further we compare the incentives to merge with Bertrand and Cournot competition. Comparing quantity with price competition we can show that a merger is more likely with Cournot competition than with Bertrand competition.}, language = {en} } @article{BruttelFriehe2015, author = {Bruttel, Lisa Verena and Friehe, Tim}, title = {A note on making humans randomize}, series = {Journal of behavioral and experimental economics}, volume = {58}, journal = {Journal of behavioral and experimental economics}, publisher = {Elsevier}, address = {New York}, issn = {2214-8043}, doi = {10.1016/j.socec.2015.06.008}, pages = {40 -- 45}, year = {2015}, abstract = {This note presents results from an experiment studying a two person 4 4 pure coordination game. We explore different strategy labels in an attempt to implement the mixed strategy equilibrium that selects all four strategies with equal probability. Such strategy labels must be free from salient properties that might be used by participants to coordinate. Testing 23 different sets of strategy labels, we identify two sets that produce a distribution of subjects' choices which approximate the uniform distribution quite well. Our results are relevant for studies intending to compare the behavior of subjects who play against a random mechanism with that of participants who play against human counterparts.}, language = {en} } @article{LueckEisenreichSpangenbergetal.1997, author = {L{\"u}ck, Erika and Eisenreich, Manfred and Spangenberg, Ute and Christl, G.}, title = {A note on geophysical prospection of archaeological structures in urban contexts in Potsdam (Germany)}, year = {1997}, language = {en} } @article{DimitrovaFernandesKoppitz2017, author = {Dimitrova, Ilinka and Fernandes, Vitor H. and Koppitz, J{\"o}rg}, title = {A note on generators of the endomorphism semigroup of an infinite countable chain}, series = {Journal of Algebra and its Applications}, volume = {16}, journal = {Journal of Algebra and its Applications}, number = {2}, publisher = {World Scientific}, address = {Singapore}, issn = {0219-4988}, doi = {10.1142/S0219498817500311}, pages = {9}, year = {2017}, abstract = {In this note, we consider the semigroup O(X) of all order endomorphisms of an infinite chain X and the subset J of O(X) of all transformations alpha such that vertical bar Im(alpha)vertical bar = vertical bar X vertical bar. For an infinite countable chain X, we give a necessary and sufficient condition on X for O(X) = < J > to hold. We also present a sufficient condition on X for O(X) = < J > to hold, for an arbitrary infinite chain X.}, language = {en} } @article{KellerLiuPeyerimhoff2021, author = {Keller, Matthias and Liu, Shiping and Peyerimhoff, Norbert}, title = {A note on eigenvalue bounds for non-compact manifolds}, series = {Mathematische Nachrichten}, volume = {294}, journal = {Mathematische Nachrichten}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0025-584X}, doi = {10.1002/mana.201900209}, pages = {1134 -- 1139}, year = {2021}, abstract = {In this article we prove upper bounds for the Laplace eigenvalues lambda(k) below the essential spectrum for strictly negatively curved Cartan-Hadamard manifolds. Our bound is given in terms of k(2) and specific geometric data of the manifold. This applies also to the particular case of non-compact manifolds whose sectional curvature tends to -infinity, where no essential spectrum is present due to a theorem of Donnelly/Li. The result stands in clear contrast to Laplacians on graphs where such a bound fails to be true in general.}, language = {en} } @article{Thiersch2019, author = {Thiersch, Craig}, title = {A note on apparent sluicing in Malagasy}, series = {Of trees and birds. A Festschrift for Gisbert Fanselow}, journal = {Of trees and birds. A Festschrift for Gisbert Fanselow}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-457-9}, doi = {10.25932/publishup-43234}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-432341}, pages = {185 -- 209}, year = {2019}, language = {en} } @article{RamirezAlegriaCheneBorissovaetal.2015, author = {Ram{\´i}rez Alegr{\´i}a, S. and Chen{\´e}, A.-N. and Borissova, J. and Kurtev, R. and Navarro, C. and Kuhn, M. and Carballo-Bello, J. A.}, title = {A not so massive cluster hosting a very massive star}, series = {Wolf-Rayet Stars : Proceedings of an International Workshop held in Potsdam, Germany, 1.-5. June 2015}, journal = {Wolf-Rayet Stars : Proceedings of an International Workshop held in Potsdam, Germany, 1.-5. June 2015}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-88477}, pages = {362}, year = {2015}, abstract = {We present the first physical characterization of the young open cluster VVVCL041. We spectroscopically observed the cluster main-sequence stellar population and a very-massive star candidate: WR62-2. CMFGEN modelling to our near-infrared spectra indicates that WR62-2 is a very luminous (10^6.4±0.2 L⊙)and massive (∼ 80M⊙) star.}, language = {en} } @article{MakhmudovMakhmudovTarkhanov2017, author = {Makhmudov, K. O. and Makhmudov, O. I. and Tarkhanov, Nikolai Nikolaevich}, title = {A nonstandard Cauchy problem for the heat equation}, series = {Mathematical Notes}, volume = {102}, journal = {Mathematical Notes}, publisher = {Pleiades Publ.}, address = {New York}, issn = {0001-4346}, doi = {10.1134/S0001434617070264}, pages = {250 -- 260}, year = {2017}, abstract = {We consider the Cauchy problem for the heat equation in a cylinder C (T) = X x (0, T) over a domain X in R (n) , with data on a strip lying on the lateral surface. The strip is of the form S x (0, T), where S is an open subset of the boundary of X. The problem is ill-posed. Under natural restrictions on the configuration of S, we derive an explicit formula for solutions of this problem.}, language = {en} } @article{Reich2013, author = {Reich, Sebastian}, title = {A nonparametric ensemble transform method for bayesian inference}, series = {SIAM journal on scientific computing}, volume = {35}, journal = {SIAM journal on scientific computing}, number = {4}, publisher = {Society for Industrial and Applied Mathematics}, address = {Philadelphia}, issn = {1064-8275}, doi = {10.1137/130907367}, pages = {A2013 -- A2024}, year = {2013}, abstract = {Many applications, such as intermittent data assimilation, lead to a recursive application of Bayesian inference within a Monte Carlo context. Popular data assimilation algorithms include sequential Monte Carlo methods and ensemble Kalman filters (EnKFs). These methods differ in the way Bayesian inference is implemented. Sequential Monte Carlo methods rely on importance sampling combined with a resampling step, while EnKFs utilize a linear transformation of Monte Carlo samples based on the classic Kalman filter. While EnKFs have proven to be quite robust even for small ensemble sizes, they are not consistent since their derivation relies on a linear regression ansatz. In this paper, we propose another transform method, which does not rely on any a priori assumptions on the underlying prior and posterior distributions. The new method is based on solving an optimal transportation problem for discrete random variables.}, language = {en} } @article{LandwehrKuehnSchefferetal.2016, author = {Landwehr, Niels and Kuehn, Nicolas M. and Scheffer, Tobias and Abrahamson, Norman A.}, title = {A Nonergodic Ground-Motion Model for California with Spatially Varying Coefficients}, series = {Bulletin of the Seismological Society of America}, volume = {106}, journal = {Bulletin of the Seismological Society of America}, publisher = {Seismological Society of America}, address = {Albany}, issn = {0037-1106}, doi = {10.1785/0120160118}, pages = {2574 -- 2583}, year = {2016}, abstract = {Traditional probabilistic seismic-hazard analysis as well as the estimation of ground-motion models (GMMs) is based on the ergodic assumption, which means that the distribution of ground motions over time at a given site is the same as their spatial distribution over all sites for the same magnitude, distance, and site condition. With a large increase in the number of recorded ground-motion data, there are now repeated observations at given sites and from multiple earthquakes in small regions, so that assumption can be relaxed. We use a novel approach to develop a nonergodic GMM, which is cast as a varying-coefficient model (VCM). In this model, the coefficients are allowed to vary by geographical location, which makes it possible to incorporate effects of spatially varying source, path, and site conditions. Hence, a separate set of coefficients is estimated for each source and site coordinate in the data set. The coefficients are constrained to be similar for spatially nearby locations. This is achieved by placing a Gaussian process prior on the coefficients. The amount of correlation is determined by the data. The spatial correlation structure of the model allows one to extrapolate the varying coefficients to a new location and trace the corresponding uncertainties. The approach is illustrated with the Next Generation Attenuation-West2 data set, using only Californian records. The VCM outperforms a traditionally estimated GMM in terms of generalization error and leads to a reduction in the aleatory standard deviation by similar to 40\%, which has important implications for seismic-hazard calculations. The scaling of the model with respect to its predictor variables such as magnitude and distance is physically plausible. The epistemic uncertainty associated with the predicted ground motions is small in places where events or stations are close and large where data are sparse.}, language = {en} } @article{Turner2019, author = {Turner, Bryan S.}, title = {A Nineteenth-Century Turning Point}, series = {Regimes of happiness : comparative and historical studies}, journal = {Regimes of happiness : comparative and historical studies}, publisher = {Anthem Press.}, address = {London}, isbn = {978-1-78308-886-7}, pages = {235 -- 248}, year = {2019}, abstract = {Happiness as the ultimate goal of human endeavour is a thread running through theology and philosophy from the ancient Greeks to modern times. Such a claim raises immediately a host of critical objections and problems relating to the idea of cultural relativism. Can the theme of happiness be continuous and how would we know that? One way to overcome this dilemma is to identify 'regimes of happiness' - that is, clusters of ideas, practices and institutions that in one way or another connect to broad ideas of human wellbeing, flourishing and satisfaction or Eudaimonia to use the word that dominates Aristotle's Nicomachean Ethics (Contreras- Vejar and Turner, 2018). Contemporary discussions of happiness almost invariably start with Aristotle (Nagel, 1972). However, the methodology here is to some extent borrowed from Michel Foucault to understand the 'genealogy' of happiness across different social and cultural formations. In the Western world one could identify an Aristotelian regime of happiness based on the idea of a sound polity and flourishing citizens. There is also a Christian regime of happiness around such figures as St. Augustine and within which there have been radical shifts most notably brought about by Luther and the Protestant Reformation. Regimes of happiness can overlap with each other and their borders are obviously fuzzy. Some regimes may last a long time in various forms. For example, Aristotle's treatment of happiness is one of the most cited versions of happiness across the West. The idea of happiness is, however, not confined to the West. For example, the Vietnamese Constitution that was devised by Ho Chi Minh, an admirer of America society, crafted the 1945 Constitution with three key words as its primary values - Independence-freedom-happiness (or niem hanh phuc). The 2013 version of the Constitution in Article 3 says, 'The state guarantees […] that people enjoy what is abundant and free for a happy life with conditions for all- round development.' One further notion behind our discussion of 'regimes of happiness' is that in principle we can detect important shifts in regimes that are associated both with specific networks of individual thinkers, and with institutional changes in the location of intellectuals in these networks. In this chapter I am especially interested in the transitions in thinking about happiness from the late eighteenth century and through the nineteenth century.}, language = {en} } @article{GoethelListekMesserschmidtetal.2021, author = {G{\"o}thel, Markus and Listek, Martin and Messerschmidt, Katrin and Schl{\"o}r, Anja and H{\"o}now, Anja and Hanack, Katja}, title = {A New Workflow to Generate Monoclonal Antibodies against Microorganisms}, series = {Applied Sciences}, volume = {11}, journal = {Applied Sciences}, number = {20}, publisher = {MDPI}, address = {Basel}, issn = {1454-5101}, doi = {10.3390/app11209359}, pages = {15}, year = {2021}, abstract = {Monoclonal antibodies are used worldwide as highly potent and efficient detection reagents for research and diagnostic applications. Nevertheless, the specific targeting of complex antigens such as whole microorganisms remains a challenge. To provide a comprehensive workflow, we combined bioinformatic analyses with novel immunization and selection tools to design monoclonal antibodies for the detection of whole microorganisms. In our initial study, we used the human pathogenic strain E. coli O157:H7 as a model target and identified 53 potential protein candidates by using reverse vaccinology methodology. Five different peptide epitopes were selected for immunization using epitope-engineered viral proteins. The identification of antibody-producing hybridomas was performed by using a novel screening technology based on transgenic fusion cell lines. Using an artificial cell surface receptor expressed by all hybridomas, the desired antigen-specific cells can be sorted fast and efficiently out of the fusion cell pool. Selected antibody candidates were characterized and showed strong binding to the target strain E. coli O157:H7 with minor or no cross-reactivity to other relevant microorganisms such as Legionella pneumophila and Bacillus ssp. This approach could be useful as a highly efficient workflow for the generation of antibodies against microorganisms.}, language = {en} } @article{GvaramadzeKniazevHamannetal.2010, author = {Gvaramadze, Vasily V. and Kniazev, Alexei Y. and Hamann, Wolf-Rainer and Berdnikov, Leonid N. and Fabrika, Sergei Nikolaevich and Valeev, Azamat F.}, title = {A new Wolf-Rayet star and its circumstellar nebula in Aquila}, issn = {0035-8711}, doi = {10.1111/j.1365-2966.2009.16126.x}, year = {2010}, abstract = {We report the discovery of a new Wolf-Rayet star in Aquila via detection of its circumstellar nebula (reminiscent of ring nebulae associated with late WN stars) using the Spitzer Space Telescope archival data. Our spectroscopic follow-up of the central point source associated with the nebula showed that it is a WN7h star (we named it WR121b). We analysed the spectrum of WR 121b by using the Potsdam Wolf-Rayet model atmospheres, obtaining a stellar temperature of similar or equal to 50 kK. The stellar wind composition is dominated by helium with similar to 20 per cent of hydrogen. The stellar spectrum is highly reddened [E(B - V) = 2.85 mag]. Adopting an absolute magnitude of M-v = 5.7, the star has a luminosity of log L/L-circle dot = 5.75 and a mass-loss rate of 10(-4.7)M(circle dot)yr(-1), and resides at a distance of 6.3 kpc. We searched for a possible parent cluster of WR 121b and found that this star is located at similar or equal to 1 degrees from the young star cluster embedded in the giant HII region W43 (containing a WN7+a/OB? star - WR121a). We also discovered a bow shock around the O9.5III star ALS 9956, located at similar or equal to 0 degrees.5 from the cluster. We discuss the possibility that WR121b and ALS 9956 are runaway stars ejected from the cluster in W43.}, language = {en} } @article{YepesAudinAlvaradoetal.2016, author = {Yepes, Hugo and Audin, Laurence and Alvarado, Alexandra and Beauval, Celine and Aguilar, Jorge and Font, Yvonne and Cotton, Fabrice}, title = {A new view for the geodynamics of Ecuador: Implication in seismogenic source definition and seismic hazard assessment}, series = {Tectonics}, volume = {35}, journal = {Tectonics}, publisher = {American Geophysical Union}, address = {Washington}, issn = {0278-7407}, doi = {10.1002/2015TC003941}, pages = {1249 -- 1279}, year = {2016}, abstract = {A new view of Ecuador's complex geodynamics has been developed in the course of modeling seismic source zones for probabilistic seismic hazard analysis. This study focuses on two aspects of the plates' interaction at a continental scale: (a) age-related differences in rheology between Farallon and Nazca plates—marked by the Grijalva rifted margin and its inland projection—as they subduct underneath central Ecuador, and (b) the rapidly changing convergence obliquity resulting from the convex shape of the South American northwestern continental margin. Both conditions satisfactorily explain several characteristics of the observed seismicity and of the interseismic coupling. Intermediate-depth seismicity reveals a severe flexure in the Farallon slab as it dips and contorts at depth, originating the El Puyo seismic cluster. The two slabs position and geometry below continental Ecuador also correlate with surface expressions observable in the local and regional geology and tectonics. The interseismic coupling is weak and shallow south of the Grijalva rifted margin and increases northward, with a heterogeneous pattern locally associated to the Carnegie ridge subduction. High convergence obliquity is responsible for the North Andean Block northeastward movement along localized fault systems. The Cosanga and Pallatanga fault segments of the North Andean Block-South American boundary concentrate most of the seismic moment release in continental Ecuador. Other inner block faults located along the western border of the inter-Andean Depression also show a high rate of moderate-size earthquake production. Finally, a total of 19 seismic source zones were modeled in accordance with the proposed geodynamic and neotectonic scheme.}, language = {en} } @article{GoesselSogomonyanMorosov1999, author = {G{\"o}ssel, Michael and Sogomonyan, Egor S. and Morosov, Andrej}, title = {A new totally error propagating compactor for arbitrary cores with digital interfaces}, year = {1999}, language = {en} } @article{IonescuBizicIonescuKhalilietal.2015, author = {Ionescu, Danny and Bizic-Ionescu, Mina and Khalili, Arzhang and Malekmohammadi, Reza and Morad, Reza Mohammad and de Beer, Dirk and Grossart, Hans-Peter}, title = {A new tool for long-term studies of POM-bacteria interactions: overcoming the century-old Bottle Effect}, series = {Scientific reports}, volume = {5}, journal = {Scientific reports}, publisher = {Nature Publ. Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep14706}, pages = {12}, year = {2015}, abstract = {Downward fluxes of particulate organic matter (POM) are the major process for sequestering atmospheric CO2 into aquatic sediments for thousands of years. Budget calculations of the biological carbon pump are heavily based on the ratio between carbon export (sedimentation) and remineralization (release to the atmosphere). Current methodologies determine microbial dynamics on POM using closed vessels, which are strongly biased towards heterotrophy due to rapidly changing water chemistry (Bottle Effect). We developed a flow-through rolling tank for long term studies that continuously maintains POM at near in-situ conditions. There, bacterial communities resembled in-situ communities and greatly differed from those in the closed systems. The active particle-associated community in the flow-through system was stable for days, contrary to hours previously reported for closed incubations. In contrast to enhanced respiration rates, the decrease in photosynthetic rates on particles throughout the incubation was much slower in our system than in traditional ones. These results call for reevaluating experimentally-derived carbon fluxes estimated using traditional methods.}, language = {en} } @article{BecciHafner2022, author = {Becci, Irene and Hafner, Johann Evangelist}, title = {A New Synagogue, a Garrison Church, and a Mosque}, series = {Space and Culture}, volume = {26}, journal = {Space and Culture}, number = {2}, publisher = {Sage Publications}, address = {Thousand Oaks, Calif.}, issn = {1552-8308}, doi = {10.1177/12063312221134572}, pages = {215 -- 228}, year = {2022}, abstract = {In postsocialist Potsdam, religious diversity has risen surprisingly in public life since 1990 although more than 80\% of the residents have no religious affiliation. City and state authorities have actively embraced issues around immigration and integration as well as the promotion of religious diversity and interreligious dialogue and have linked this to the agenda of rejuvenating the city's religious heritage. For years, negotiations have been going on about the need of a mosque, the reconstructions of a synagogue and the so-called "Garrison Church," a landmark military church building. These initiatives have been dominating the public space for different reasons. They implied, beyond religion, questions of memory, identity, immigration, and culture. This article puts these three cases into perspective to offer a nuanced understanding of the importance of religious spaces in secular contexts considering city politics.}, language = {en} } @article{SrokaGodunkoRutschmannetal.2019, author = {Sroka, Pavel and Godunko, Roman J. and Rutschmann, Sereina and Angeli, Kamila B. and Salles, Frederico F. and Gattolliat, Jean-Luc}, title = {A new species of Bungona in Turkey (Ephemeroptera, Baetidae)}, series = {Zoosytematics and evolution}, volume = {95}, journal = {Zoosytematics and evolution}, number = {1}, publisher = {Pensoft Publ.}, address = {Sofia}, issn = {1860-0743}, doi = {10.3897/zse.95.29487}, pages = {1 -- 13}, year = {2019}, abstract = {By using an integrative approach, we describe a new species of mayfly, Bungona (Chopralla) pontica sp. n., from Turkey. The discovery of a representative of the tropical mayfly genus Bungona in the Middle East is rather unexpected. The new species shows all the main morphological characters of the subgenus Chopralla, which has its closest related species occurring in southeastern Asia. Barcoding clearly indicated that the new species represents an independent lineage isolated for a very long time from other members of the complex. The claw is equipped with two rows of three or four flattened denticles. This condition is a unique feature of Bungona (Chopralla) pontica sp. n. among West Palaearctic mayfly species. Within the subgenus Chopralla, the species can be identified by the presence of a simple, not bifid right prostheca (also present only in Bungona (Chopralla) liebenauae (Soldan, Braasch \& Muu, 1987)), the shape of the labial palp, and the absence of protuberances on pronotum.}, language = {en} } @article{GoesselSogomonyan1996, author = {G{\"o}ssel, Michael and Sogomonyan, Egor S.}, title = {A new self-testing parity checker for ultra-reliable applications}, year = {1996}, language = {en} } @article{AssagraAltafimdoCarmoetal.2020, author = {Assagra, Yuri A.O. and Altafim, Ruy Alberto Pisani and do Carmo, Joao P. and Altafim, Ruy A.C. and Rychkov, Dmitry and Wirges, Werner and Gerhard, Reimund}, title = {A new route to piezo-polymer transducers: 3D printing of polypropylene ferroelectrets}, series = {IEEE transactions on dielectrics and electrical insulation}, volume = {27}, journal = {IEEE transactions on dielectrics and electrical insulation}, number = {5}, publisher = {Inst. of Electr. and Electronics Engineers}, address = {Piscataway}, issn = {1070-9878}, doi = {10.1109/TDEI.2020.008461}, pages = {1668 -- 1674}, year = {2020}, abstract = {Here, a promising approach for producing piezo-polymer transducers in a one-step process is presented. Using 3D-printing technology and polypropylene (PP) filaments, we are able to print a two-layered film structure with regular cavities of precisely controlled size and shape. It is found that the 3D-printed samples exhibit piezoelectric coefficients up to 200 pC/N, similar to those of other PP ferroelectrets, and their temporal and thermal behavior is in good agreement with those known of PP ferroelectrets. The piezoelectric response strongly decreases for applied pressures above 20 kPa, as the pressure in the air-filled cavities strongly influences the overall elastic modulus of ferroelectrets.}, language = {en} } @article{LiebigHenningSarhanetal.2018, author = {Liebig, Ferenc and Henning, Ricky and Sarhan, Radwan Mohamed and Prietzel, Claudia Christina and Bargheer, Matias and Koetz, Joachim}, title = {A new route to gold nanoflowers}, series = {Nanotechnology}, volume = {29}, journal = {Nanotechnology}, number = {18}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0957-4484}, doi = {10.1088/1361-6528/aaaffd}, pages = {8}, year = {2018}, abstract = {Catanionic vesicles spontaneously formed by mixing the anionic surfactant bis(2-ethylhexyl)sulfosuccinate sodium salt with the cationic surfactant cetyltrimethylammonium bromide were used as a reducing medium to produce gold clusters, which are embedded and well-ordered into the template phase. The gold clusters can be used as seeds in the growth process that follows by adding ascorbic acid as a mild reducing component. When the ascorbic acid was added very slowly in an ice bath round-edged gold nanoflowers were produced. When the same experiments were performed at room temperature in the presence of Ag+ ions, sharp-edged nanoflowers could be synthesized. The mechanism of nanoparticle formation can be understood to be a non-diffusion-limited Ostwald ripening process of preordered gold nanoparticles embedded in catanionic vesicle fragments. Surface-enhanced Raman scattering experiments show an excellent enhancement factor of 1.7 . 10(5) for the nanoflowers deposited on a silicon wafer.}, language = {en} } @article{ChoiSchmidtTinnefeldetal.2019, author = {Choi, Youngeun and Schmidt, Carsten and Tinnefeld, Philip and Bald, Ilko and R{\"o}diger, Stefan}, title = {A new reporter design based on DNA origami nanostructures for quantification of short oligonucleotides using microbeads}, series = {Scientific Reports}, journal = {Scientific Reports}, number = {9}, publisher = {Macmillan Publishers Limited}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-019-41136-x}, pages = {8}, year = {2019}, abstract = {The DNA origami technique has great potential for the development of brighter and more sensitive reporters for fluorescence based detection schemes such as a microbead-based assay in diagnostic applications. The nanostructures can be programmed to include multiple dye molecules to enhance the measured signal as well as multiple probe strands to increase the binding strength of the target oligonucleotide to these nanostructures. Here we present a proof-of-concept study to quantify short oligonucleotides by developing a novel DNA origami based reporter system, combined with planar microbead assays. Analysis of the assays using the VideoScan digital imaging platform showed DNA origami to be a more suitable reporter candidate for quantification of the target oligonucleotides at lower concentrations than a conventional reporter that consists of one dye molecule attached to a single stranded DNA. Efforts have been made to conduct multiplexed analysis of different targets as well as to enhance fluorescence signals obtained from the reporters. We therefore believe that the quantification of short oligonucleotides that exist in low copy numbers is achieved in a better way with the DNA origami nanostructures as reporters.}, language = {en} } @article{KindermannDoblerNiedeggenetal.2021, author = {Kindermann, Liana and Dobler, Magnus and Niedeggen, Daniela and Linst{\"a}dter, Anja}, title = {A new protocol for estimation of woody aboveground biomass in disturbance-prone ecosystems}, series = {Ecological indicators : integrating monitoring, assessment and management}, volume = {135}, journal = {Ecological indicators : integrating monitoring, assessment and management}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1470-160X}, doi = {10.1016/j.ecolind.2021.108466}, pages = {16}, year = {2021}, abstract = {Almost one third of global drylands are open forests and savannas, which are typically shaped by frequent natural disturbances such as wildfire and herbivory. Studies on ecosystem functions and services of woody vegetation require robust estimates of aboveground biomass (AGB). However, most methods have been developed for comparatively undisturbed forest ecosystems. As they are not tailored to accurately quantify AGB of small and irregular growth forms, their application on these growth forms may lead to unreliable or even biased AGB estimates in disturbance-prone dryland ecosystems. Moreover, these methods cannot quantify AGB losses caused by disturbance agents. Here we propose a methodology to estimate individual-and stand-level woody AGB in disturbance-prone ecosystems. It consists of flexible field sampling routines and estimation workflows for six growth classes, delineated by size and damage criteria. It also comprises a detailed damage assessment, harnessing the ecological archive of woody growth for past disturbances. Based on large inventories collected along steep gradients of elephant disturbances in African dryland ecosystems, we compared the AGB estimates generated with our proposed method against estimates from a less adapted forest inventory method. We evaluated the necessary stepwise procedures of method adaptation and analyzed each step's effect on stand-level AGB estimation. We further explored additional advantages of our proposed method with regard to disturbance impact quantification. Results indicate that a majority of growth forms and individuals in savanna vegetation could only be assessed if methods of AGB estimation were adapted to the conditions of a disturbance-prone ecosystem. Furthermore, our damage assessment demonstrated that one third to half of all woody AGB was lost to disturbances. Consequently, less adapted methods may be insufficient and are likely to render inaccurate AGB estimations. Our proposed method has the potential to accurately quantify woody AGB in disturbance-prone ecosystems, as well as AGB losses. Our method is more time consuming than conventional allometric approaches, yet it can cover sufficient areas within reasonable timespans, and can also be easily adapted to alternative sampling schemes.}, language = {en} } @article{Schmidt1997, author = {Schmidt, Hans-J{\"u}rgen}, title = {A new proof of Birkhoff{\"i}s theorem}, year = {1997}, language = {en} } @article{Trauth2014, author = {Trauth, Martin H.}, title = {A new probabilistic technique to build an age model for complex stratigraphic sequences}, series = {Quaternary geochronology : the international research and review journal on advances in quaternary dating techniques}, volume = {22}, journal = {Quaternary geochronology : the international research and review journal on advances in quaternary dating techniques}, publisher = {Elsevier}, address = {Oxford}, issn = {1871-1014}, doi = {10.1016/j.quageo.2014.03.001}, pages = {65 -- 71}, year = {2014}, abstract = {The age models of fluvio-lacustrine sedimentary sequences are often subject of discussions in paleoclimate research. The techniques employed to build an age model are very diverse, ranging from visual or intuitive estimation of the age-depth relationship over linear or spline interpolations between age control points to sophisticated Bayesian techniques also taking into account the most likely deposition times of the type of sediment within the sequence. All these methods, however, fail in detecting abrupt variations in sedimentation rates, including the possibility of episodes of no deposition (hiatus), which is the strength of the method presented in this work. The new technique simply compares the deposition time of equally thick sediment slices from the differences of subsequent radiometric age dates and the unit deposition times of the various sediment types. The percentage overlap of the distributions of these two sources of information, together with the evidence from the sedimentary record, helps to build an age model of complex sequences including abrupt variations in the rate of deposition including one or many hiatuses. (C) 2014 Elsevier B.V. All rights reserved.}, language = {en} } @article{ShpritsAllisonWangetal.2022, author = {Shprits, Yuri and Allison, Hayley J. and Wang, Dedong and Drozdov, Alexander and Szabo-Roberts, Matyas and Zhelavskaya, Irina and Vasile, Ruggero}, title = {A new population of ultra-relativistic electrons in the outer radiation zone}, series = {Journal of geophysical research : Space physics}, volume = {127}, journal = {Journal of geophysical research : Space physics}, number = {5}, publisher = {American Geophysical Union}, address = {Washington}, issn = {2169-9380}, doi = {10.1029/2021JA030214}, pages = {34}, year = {2022}, abstract = {Van Allen Probes measurements revealed the presence of the most unusual structures in the ultra-relativistic radiation belts. Detailed modeling, analysis of pitch angle distributions, analysis of the difference between relativistic and ultra-realistic electron evolution, along with theoretical studies of the scattering and wave growth, all indicate that electromagnetic ion cyclotron (EMIC) waves can produce a very efficient loss of the ultra-relativistic electrons in the heart of the radiation belts. Moreover, a detailed analysis of the profiles of phase space densities provides direct evidence for localized loss by EMIC waves. The evolution of multi-MeV fluxes shows dramatic and very sudden enhancements of electrons for selected storms. Analysis of phase space density profiles reveals that growing peaks at different values of the first invariant are formed at approximately the same radial distance from the Earth and show the sequential formation of the peaks from lower to higher energies, indicating that local energy diffusion is the dominant source of the acceleration from MeV to multi-MeV energies. Further simultaneous analysis of the background density and ultra-relativistic electron fluxes shows that the acceleration to multi-MeV energies only occurs when plasma density is significantly depleted outside of the plasmasphere, which is consistent with the modeling of acceleration due to chorus waves.}, language = {en} } @article{Ganghof2018, author = {Ganghof, Steffen}, title = {A new political system model}, series = {European Journal for Political Research}, volume = {57}, journal = {European Journal for Political Research}, number = {2}, publisher = {Wiley}, address = {Hoboken}, issn = {0304-4130}, doi = {10.1111/1475-6765.12224}, pages = {261 -- 281}, year = {2018}, abstract = {Semi-parliamentary government is a distinct executive-legislative system that mirrors semi-presidentialism. It exists when the legislature is divided into two equally legitimate parts, only one of which can dismiss the prime minister in a no-confidence vote. This system has distinct advantages over pure parliamentary and presidential systems: it establishes a branch-based separation of powers and can balance the 'majoritarian' and 'proportional' visions of democracy without concentrating executive power in a single individual. This article analyses bicameral versions of semi-parliamentary government in Australia and Japan, and compares empirical patterns of democracy in the Australian Commonwealth as well as New South Wales to 20 advanced parliamentary and semi-presidential systems. It discusses new semi-parliamentary designs, some of which do not require formal bicameralism, and pays special attention to semi-parliamentary options for democratising the European Union.}, language = {en} } @article{SogomonyanGoessel1995, author = {Sogomonyan, Egor S. and G{\"o}ssel, Michael}, title = {A new parity preserving multi-input signature analyser}, year = {1995}, language = {en} } @article{VandenWyngaertSetoRojasJimenezetal.2017, author = {Van den Wyngaert, Silke and Seto, Kensuke and Rojas-Jimenez, Keilor and Kagami, Maiko and Grossart, Hans-Peter}, title = {A New Parasitic Chytrid, Staurastromyces oculus (Rhizophydiales, Staurastromy-cetaceae fam. nov.), Infecting the Freshwater Desmid Staurastrum sp.}, series = {Protist}, volume = {168}, journal = {Protist}, publisher = {Elsevier}, address = {Jena}, issn = {1434-4610}, doi = {10.1016/j.protis.2017.05.001}, pages = {392 -- 407}, year = {2017}, abstract = {Chytrids are a diverse group of ubiquitous true zoosporic fungi. The recent molecular discovery of a large diversity of undescribed chytrids has raised awareness on their important, but so far understudied ecological role in aquatic ecosystems. In the pelagic zone, of both freshwater and marine ecosystems, many chytrid species have been morphologically described as parasites on almost all major groups of phytoplankton. However, the majority of these parasitic chytrids has rarely been isolated and lack DNA sequence data, resulting in a large proportion of "dark taxa" in databases. Here, we report on the isolation and in-depth morphological, molecular and host range characterization of a chytrid infecting the common freshwater desmid Staurastrum sp. We provide first insights on the metabolic activity of the different chytrid development stages by using the vital dye FUN (R)-1 (2-chloro-4-[2,3-dihydro-3-methyl-[benzo-1,3-thiazol-2-yl]-methylidene]-1-phenylquinolinium iodide). Cross infection experiments suggest that this chytrid is an obligate parasite and specific for the genus Staurastrum sp. Phylogenetic analysis, based on ITS1-5.8S-ITS2 and 28S rDNA sequences, placed it in the order Rhizophydiales. Based on the unique zoospore ultrastructure, combined with thallus morphology, and molecular phylogenetic placement, we describe this parasitic chytrid as a new genus and species Staurastromyces oculus, within a new family Staurastromycetaceae. (C) 2017 Elsevier GmbH. All rights reserved.}, language = {en} } @article{FruhnerWantke1996, author = {Fruhner, Horst and Wantke, K.-D.}, title = {A new oscillating bubble technique for measuring surface dilational}, issn = {0927-7757}, year = {1996}, language = {en} } @article{DietrichBehrensWilke2018, author = {Dietrich, Marcel and Behrens, Harald and Wilke, Max}, title = {A new optical cell for in situ Raman spectroscopy, and its application to study sulfur-bearing fluids at elevated pressures and temperatures}, series = {American mineralogist : an international journal of earth and planetary materials}, volume = {103}, journal = {American mineralogist : an international journal of earth and planetary materials}, number = {3}, publisher = {Mineralogical Society of America}, address = {Chantilly}, issn = {0003-004X}, doi = {10.2138/am-2018-6244}, pages = {418 -- 429}, year = {2018}, abstract = {Sulfur is an important component in volcanic gases at the Earth surface but also present in the deep Earth in hydrothermal or magmatic fluids. Little is known about the evolution of such fluids during ascent in the crust. A new optical cell was developed for in situ Raman spectroscopic investigations on fluids allowing abrupt or continuous changes of pressure up to 200 MPa at temperatures up to 750 degrees C. The concept is based on a flexible gold bellow, which separates the sample fluid from the pressure medium water. To avoid reactions between aggressive fluids and the pressure cell, steel components in contact with the fluid are shielded by gold foil. The cell was tested to study redox reactions in fluids using aqueous ammonium sulfate solutions as a model system. During heating at constant pressure of 130 MPa, sulfate ions transform first to HSO4- ions and then to molecular units such as H2SO4. Variation of pressure shows that the stability of sulfate species relies on fluid density, i.e., highly charged species are stable only in high-density fluids. Partial decomposition of ammonium was evident above 550 degrees C by the occurrence of a nitrogen peak in the Raman spectra. Reduced sulfur species were observed above 700 degrees C by Raman signals near 2590 cm(-1) assigned to HS- and H2S. No clear evidence for the formation of sulfur dioxide was found in contrary to previous studies on aqueous H2SO4, suggesting very reducing conditions in our experiments. Fluid-mineral interaction was studied by inserting into the cell a small, semi-open capsule filled with a mixture of pyrite and pyrrhotite. Oxidation of the sample assembly was evident by transformation of pyrite to pyrrhotite. As a consequence, sulfide species were observed in the fluid already at temperatures of similar to 600 degrees C.}, language = {en} } @article{NikoloskiMaySelbig2009, author = {Nikoloski, Zoran and May, Patrick and Selbig, Joachim}, title = {A new network model explains the evolution of plant-specific metabolic networks}, issn = {1095-6433}, doi = {10.1016/j.cbpa.2009.04.567}, year = {2009}, language = {en} } @article{ArwornDenecke1997, author = {Arworn, Srichan and Denecke, Klaus-Dieter}, title = {A new methods to study subvariety lattices of semigroup varieties}, year = {1997}, language = {en} } @article{Goessel1999, author = {G{\"o}ssel, Michael}, title = {A new method of redundancy addition for circuit optimization}, series = {Preprint / Universit{\"a}t Potsdam, Institut f{\"u}r Informatik}, volume = {1999, 08}, journal = {Preprint / Universit{\"a}t Potsdam, Institut f{\"u}r Informatik}, publisher = {Univ.}, address = {Potsdam}, issn = {0946-7580}, pages = {9 Bl.}, year = {1999}, language = {en} } @article{BissingerJanderTittel2000, author = {Bissinger, Vera and Jander, J{\"o}rn and Tittel, J{\"o}rg}, title = {A new medium free of organic carbon to cultivate organisms from extremely acidic mining lakes (pH 2.7)}, year = {2000}, abstract = {An algal culture medium was developed which reflects the extreme chemical conditions of acidic mining lakes (pH 2.7, high concentrations of iron and sulfate) and remains stable without addition of organic carbon sources. It enables controlled experiments e.g. on the heterotrophic potential of pigmented flagellates in the laboratory. Various plankton organisms isolated from acidic lakes were successfully cultivated in this medium. The growth rates of an Chlamydomonas- isolate from acidic mining lakes were assessed by measuring cell densities under pure autotrophic and heterotrophic conditions (with glucose as organic C-source) and showed values of 0.74 and 0.40, respectively.}, language = {en} } @article{ShachamIdanShaviv2015, author = {Shacham, T. and Idan, I. and Shaviv, N. J.}, title = {A new mechanism for long long-term pulsations of hot stars?}, series = {Wolf-Rayet Stars : Proceedings of an International Workshop held in Potsdam, Germany, 1.-5. June 2015}, journal = {Wolf-Rayet Stars : Proceedings of an International Workshop held in Potsdam, Germany, 1.-5. June 2015}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-88058}, pages = {209 -- 212}, year = {2015}, abstract = {We suggest several ideas which when combined could lead to a new mechanism for long-term pulsations of very hot and luminous stars. These involve the interplay between convection, radiation, atmospheric clumping and winds, which collectively feed back to stellar expansion and contraction. We discuss these ideas and point out the future work required in order to fill in the blanks.}, language = {en} } @article{ObbardShiRobertsetal.2020, author = {Obbard, Darren J. and Shi, Mang and Roberts, Katherine E. and Longdon, Ben and Dennis, Alice B.}, title = {A new lineage of segmented RNA viruses infecting animals}, series = {Virus Evolution}, volume = {6}, journal = {Virus Evolution}, number = {1}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {2057-1577}, doi = {10.1093/ve/vez061}, pages = {1 -- 10}, year = {2020}, abstract = {Metagenomic sequencing has revolutionised our knowledge of virus diversity, with new virus sequences being reported faster than ever before. However, virus discovery from metagenomic sequencing usually depends on detectable homology: without a sufficiently close relative, so-called 'dark' virus sequences remain unrecognisable. An alternative approach is to use virus-identification methods that do not depend on detecting homology, such as virus recognition by host antiviral immunity. For example, virus-derived small RNAs have previously been used to propose 'dark' virus sequences associated with the Drosophilidae (Diptera). Here, we combine published Drosophila data with a comprehensive search of transcriptomic sequences and selected meta-transcriptomic datasets to identify a completely new lineage of segmented positive-sense single-stranded RNA viruses that we provisionally refer to as the Quenyaviruses. Each of the five segments contains a single open reading frame, with most encoding proteins showing no detectable similarity to characterised viruses, and one sharing a small number of residues with the RNA-dependent RNA polymerases of single- and double-stranded RNA viruses. Using these sequences, we identify close relatives in approximately 20 arthropods, including insects, crustaceans, spiders, and a myriapod. Using a more conserved sequence from the putative polymerase, we further identify relatives in meta-transcriptomic datasets from gut, gill, and lung tissues of vertebrates, reflecting infections of vertebrates or of their associated parasites. Our data illustrate the utility of small RNAs to detect viruses with limited sequence conservation, and provide robust evidence for a new deeply divergent and phylogenetically distinct RNA virus lineage.}, language = {en} } @article{Ariel2018, author = {Ariel, Yaakov S.}, title = {A New Kind of Jew}, series = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien [23 (2017)] = JewBus, Jewish Hindus \& other Jewish Encounters with East Asian Religions}, journal = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien [23 (2017)] = JewBus, Jewish Hindus \& other Jewish Encounters with East Asian Religions}, number = {23}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-418-0}, issn = {1614-6492}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-408952}, pages = {133 -- 148}, year = {2018}, abstract = {The article examines Allen Ginsberg's spiritual path, and places his interest in Asian religions within larger cultural agendas and life choices. While identifying as a Jew, Ginsberg wished to transcend beyond his parents' orbit and actively sought to create an inclusive, tolerant, and permissive society where persons such as himself could live and create at ease. He chose elements from the Christian, Jewish, Native-American, Hindu, and Buddhist traditions, weaving them together into an ever-growing cultural and spiritual quilt. The poet never underwent a conversion experience or restricted his choices and freedoms. In Ginsberg's understanding, Buddhism was a universal, non-theistic religion that meshed well with an individualist outlook, and worked toward personal solace and mindfulness. He and other Jews saw no contradiction between enchantment with Buddhism and their Jewish identity.}, language = {en} } @article{GraubaumLuderZunft2004, author = {Graubaum, Hans-Joachim and Luder, W. and Zunft, Hans-Joachim Franz}, title = {A new isolated soy protein with high levels of nondenaturated protein shows twice the cholesterol-lowering effect of a commercial isolated soy protein}, issn = {0022-3166}, year = {2004}, language = {en} } @article{HeilerNahavandiAlbrecht2010, author = {Heiler, Katharina C. M. and Nahavandi, Nahid and Albrecht, Christian}, title = {A new invasion into an Ancient lake : the invasion history of the dreissenid mussel Mytilopsis leucophaeata (Conrad, 1831) and its first record in the Caspian sea}, issn = {0076-2997}, doi = {10.4002/040.053.0112}, year = {2010}, language = {en} } @article{FruhnerWantke1996, author = {Fruhner, Horst and Wantke, K.-D.}, title = {A new instrument for measuring the viscoelastic properties of dilute polymer solutions}, year = {1996}, language = {en} } @article{VoitHeistermann2022, author = {Voit, Paul and Heistermann, Maik}, title = {A new index to quantify the extremeness of precipitation across scales}, series = {NHESS - Natural Hazards and Earth System Sciences}, volume = {22}, journal = {NHESS - Natural Hazards and Earth System Sciences}, edition = {8}, publisher = {Copernicus}, address = {Katlenburg-Lindau}, issn = {1684-9981}, doi = {10.5194/nhess-22-2791-2022}, pages = {2791 -- 2805}, year = {2022}, abstract = {Quantifying the extremeness of heavy precipitation allows for the comparison of events. Conventional quantitative indices, however, typically neglect the spatial extent or the duration, while both are important to understand potential impacts. In 2014, the weather extremity index (WEI) was suggested to quantify the extremeness of an event and to identify the spatial and temporal scale at which the event was most extreme. However, the WEI does not account for the fact that one event can be extreme at various spatial and temporal scales. To better understand and detect the compound nature of precipitation events, we suggest complementing the original WEI with a "cross-scale weather extremity index" (xWEI), which integrates extremeness over relevant scales instead of determining its maximum. Based on a set of 101 extreme precipitation events in Germany, we outline and demonstrate the computation of both WEI and xWEI. We find that the choice of the index can lead to considerable differences in the assessment of past events but that the most extreme events are ranked consistently, independently of the index. Even then, the xWEI can reveal cross-scale properties which would otherwise remain hidden. This also applies to the disastrous event from July 2021, which clearly outranks all other analyzed events with regard to both WEI and xWEI. While demonstrating the added value of xWEI, we also identify various methodological challenges along the required computational workflow: these include the parameter estimation for the extreme value distributions, the definition of maximum spatial extent and temporal duration, and the weighting of extremeness at different scales. These challenges, however, also represent opportunities to adjust the retrieval of WEI and xWEI to specific user requirements and application scenarios.}, language = {en} } @article{TischendorfRiederFoersteretal.2004, author = {Tischendorf, Gerhard and Rieder, M. and F{\"o}rster, Hans-J{\"u}rgen and Gottesmann, B{\"a}rbel and Guidotti, C. V.}, title = {A new graphical presentation and subdivision of potassium micas}, issn = {0026-461X}, year = {2004}, abstract = {A system based on variation of the octahedrally coordinated cations is proposed for graphical presentation and subdivision of tri- and dioctahedral K micas, which makes use of elemental differences (in a.p.f.u.): (Mg - Li) [= mgli] and (Fe-tot + Mn + Ti - Al-VI) [= feal]. All common true tri- and dioctahedral K micas are shown in a single polygon outlined by seven main compositional points forming its vertices. Sequentially clockwise, starting from Mg-3 (phlogopite), these points are: Mg2.5Al0.5, Al(2.167)square(0.833), Al1.75Li1.25, Li2Al (polylithionite), Fe22+Li, and Fe-3(2+) (annite). Trilithionite (Li1.5Al1.5), Li1.5Fe2+Al0.5, Fe22+Mg, and Mg2Fe2+ are also located on the perimeter of the polygon. IMA-siderophyllite (Fe22+Al) and muscovite (Al(2)square) plot inside. The classification conforms with the IMA-approved mica nomenclature and differentiates among the following mica species according to their position in a diagram consisting of nigh and feal axes plotted orthogonally; trioctahedral: phlogopite, biotite, siderophyllite, annite, zinnwaldite, lepidolite and tainiolite: dioctahedral: muscovite, phengite and celadonite. Potassium micas with [Si] <2.5 a.p.f.u. including IMA-siderophyllite, KFe22+AlAl2Si2O10(OH)(2), and IMA-eastonite, KMg2AlAl2Si2O10(OH)(2) seem not to form in nature. The proposed subdivision has several advantages. All common true, trioctahedral and dioctahedral K micas, whether Li-bearing or Li-free, are shown within one diagram, which is easy to use and gives every mica composition an unambiguously defined name. Mica analyses with Fe2+, Fe3+, Fe2+ + Fe3+, or Fe-tot can be considered, which is particularly Valuable for microprobe analyses. It facilitates easy reconstruction of evolutionary pathways of mica compositions during crystallization, a feature having key importance in petrologically oriented research. Equally important, the subdivision has great potential for understanding many of the crystal-chemistry features of the K micas. In turn this may allow one to recognize and discriminate the extent to which crystal chemistry or bulk composition controls the occurrence of some seemingly possible or hypothetical K mica}, language = {en} } @article{HempKehlHelleretal.2010, author = {Hemp, Claudia and Kehl, Siegfried and Heller, Klaus-Gerhard and Waegele, Johann Wolfgang and Hemp, Andreas}, title = {A new genus of African Karniellina (Orthoptera, Tettigoniidae, Conocephalinae, Conocephalini) : integrating morphological, molecular and bioacoustical data}, issn = {0307-6970}, doi = {10.1111/j.1365-3113.2010.00528.x}, year = {2010}, abstract = {Melanoscirtes gen.n. is established within Karniellina. The members of this subtribe are small conocephaline bush crickets, confined to Africa. Melanoscirtes is erected on Phlesirtes kibonotensis, a species restricted to forest clearings and forest edge in the submontane and montane zones of Mt. Kilimanjaro. A subspecies, M. kibonotensis uguenoensis, is described from the North Pare mountains, a mountain range of the Eastern Arc adjacent to Mt. Kilimanjaro. Further species of Melanoscirtes occur on other mountain ranges of the northern branch of the Eastern Arc mountains of northern Tanzania and southern Kenya. The South Pare mountains harbour M. shengenae; the West Usambaras, M. usambarensis, and the Taita Hills, M. taitensis. All species and subspecies of Melanoscirtes exhibit a similar morphology and occupy analogous habitats on the respective mountains. The song patterns for all species found within this genus are very similar, and this, together with evidence from molecular data, suggests that allopatric speciation is the reason for the biogeographic pattern found in this genus. A key for the subspecies and species of Melanoscirtes is provided.}, language = {en} } @article{HempVojeHelleretal.2010, author = {Hemp, Claudia and Voje, Kjetil Lysne and Heller, Klaus-Gerhard and Warchalowska-Sliwa, Elzbieta and Hemp, Andreas}, title = {A new genus of African Acrometopini (Tettigoniidae: Phaneropterinae) based on morphology, chromosomes, acoustics, distribution, and molecular data, and the description of a new species}, issn = {0024-4082}, doi = {10.1111/j.1096-3642.2009.00542.x}, year = {2010}, abstract = {A new genus, Altihoratosphaga, is erected for species formerly assigned to Horatosphaga Schaum, 1853, and a new species is described. Four species are included in Altihoratosphaga: Altihoratosphaga nomima (Karsch, 1896), Altihoratosphaga montivaga (Sjostedt, 1909), Altihoratosphaga nou (Hemp, 2007) and Altihoratosphaga hanangensis sp. nov. All four species are restricted to Tanzanian localities, and, except for A. nomima, for which no ecological data are available, are confined to montane forest habitats. Data on ecology, acoustics, chromosomes, and molecular relationships are provided, as well as a key to Altihoratosphaga species. The present-day distribution of Altihoratosphaga species suggests former migration events at times when wetter and colder climatic fluctuations favoured connections between montane forest communities, which today are isolated, enabling flightless taxa such as Altihoratosphaga and Monticolaria to spread.}, language = {en} } @article{HempHellerWarchalowskaSliwaetal.2010, author = {Hemp, Claudia and Heller, Klaus-Gerhard and Warchalowska-Sliwa, Elzbieta and Hemp, Andreas}, title = {A new genus and species of African Phaneropterinae (Orthoptera: Tettigoniidae), with data on its ecology, bioacoustics and chromosomes}, issn = {1439-6092}, doi = {10.1007/s13127-010-0013-3}, year = {2010}, abstract = {A new genus is proposed for a new East African Phaneropterinae species, Lunidia viridis, occurring on Mt. Kilimanjaro, Tanzania. Based on 33 records, notes on distribution and habitat are given, as well as acoustical data provided. Climate and vegetation parameters obtained along several transects on Mt. Kilimanjaro were evaluated describing the ecological niche of the new species. This interdisciplinary approach allows not only a profound characterisation of the ecological demands of the new genus but also predictions of the potential distribution area, which is tested for the first time for an African bush cricket species. Lunidia viridis n. gen. n. sp. occurs within humid and perhumid forests and Chagga home gardens, avoiding subhumid conditions on the mountain. It is found from 1,330 m upwards on the southern slopes, whereas the same ecological conditions are expressed from 1,930 m upwards on the drier northern slopes. Lunidia viridis has an unusually complex and variable song, which is described from field and laboratory recordings. The FISH technique for characterizing chromosomes is applied for the first time for an African species; L. viridis exhibits a karyotype typical for most Tettigoniidae.}, language = {en} } @article{ChengDennisOsuohaetal.2023, author = {Cheng, Feng and Dennis, Alice B. and Osuoha, Josephine Ijeoma and Canitz, Julia and Kirschbaum, Frank and Tiedemann, Ralph}, title = {A new genome assembly of an African weakly electric fish (Campylomormyrus compressirostris, Mormyridae) indicates rapid gene family evolution in Osteoglossomorpha}, series = {BMC genomics}, volume = {24}, journal = {BMC genomics}, number = {1}, publisher = {BMC}, address = {London}, issn = {1471-2164}, doi = {10.1186/s12864-023-09196-6}, pages = {13}, year = {2023}, abstract = {Background Teleost fishes comprise more than half of the vertebrate species. Within teleosts, most phylogenies consider the split between Osteoglossomorpha and Euteleosteomorpha/Otomorpha as basal, preceded only by the derivation of the most primitive group of teleosts, the Elopomorpha. While Osteoglossomorpha are generally species poor, the taxon contains the African weakly electric fish (Mormyroidei), which have radiated into numerous species. Within the mormyrids, the genus Campylomormyrus is mostly endemic to the Congo Basin. Campylomormyrus serves as a model to understand mechanisms of adaptive radiation and ecological speciation, especially with regard to its highly diverse species-specific electric organ discharges (EOD). Currently, there are few well-annotated genomes available for electric fish in general and mormyrids in particular. Our study aims at producing a high-quality genome assembly and to use this to examine genome evolution in relation to other teleosts. This will facilitate further understanding of the evolution of the osteoglossomorpha fish in general and of electric fish in particular. Results A high-quality weakly electric fish (C. compressirostris) genome was produced from a single individual with a genome size of 862 Mb, consisting of 1,497 contigs with an N50 of 1,399 kb and a GC-content of 43.69\%. Gene predictions identified 34,492 protein-coding genes, which is a higher number than in the two other available Osteoglossomorpha genomes of Paramormyrops kingsleyae and Scleropages formosus. A Computational Analysis of gene Family Evolution (CAFE5) comparing 33 teleost fish genomes suggests an overall faster gene family turnover rate in Osteoglossomorpha than in Otomorpha and Euteleosteomorpha. Moreover, the ratios of expanded/contracted gene family numbers in Osteoglossomorpha are significantly higher than in the other two taxa, except for species that had undergone an additional genome duplication (Cyprinus carpio and Oncorhynchus mykiss). As potassium channel proteins are hypothesized to play a key role in EOD diversity among species, we put a special focus on them, and manually curated 16 Kv1 genes. We identified a tandem duplication in the KCNA7a gene in the genome of C. compressirostris. Conclusions We present the fourth genome of an electric fish and the third well-annotated genome for Osteoglossomorpha, enabling us to compare gene family evolution among major teleost lineages. Osteoglossomorpha appear to exhibit rapid gene family evolution, with more gene family expansions than contractions. The curated Kv1 gene family showed seven gene clusters, which is more than in other analyzed fish genomes outside Osteoglossomorpha. The KCNA7a, encoding for a potassium channel central for EOD production and modulation, is tandemly duplicated which may related to the diverse EOD observed among Campylomormyrus species.}, language = {en} } @article{NeherKniepertElimelechetal.2016, author = {Neher, Dieter and Kniepert, Juliane and Elimelech, Arik and Koster, L. Jan Anton}, title = {A New Figure of Merit for Organic Solar Cells with Transport-limited Photocurrents}, series = {Scientific reports}, volume = {6}, journal = {Scientific reports}, publisher = {Nature Publ. Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep24861}, pages = {E2348 -- E2349}, year = {2016}, abstract = {Compared to their inorganic counterparts, organic semiconductors suffer from relatively low charge carrier mobilities. Therefore, expressions derived for inorganic solar cells to correlate characteristic performance parameters to material properties are prone to fail when applied to organic devices. This is especially true for the classical Shockley-equation commonly used to describe current-voltage (JV)-curves, as it assumes a high electrical conductivity of the charge transporting material. Here, an analytical expression for the JV-curves of organic solar cells is derived based on a previously published analytical model. This expression, bearing a similar functional dependence as the Shockley-equation, delivers a new figure of merit a to express the balance between free charge recombination and extraction in low mobility photoactive materials. This figure of merit is shown to determine critical device parameters such as the apparent series resistance and the fill factor.}, language = {en} } @article{NeherKniepertElimelechetal.2016, author = {Neher, Dieter and Kniepert, Juliane and Elimelech, Arik and Koster, L. Jan Anton}, title = {A New Figure of Merit for Organic Solar Cells with Transport-limited Photocurrents}, series = {Scientific reports}, volume = {6}, journal = {Scientific reports}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep24861}, pages = {9}, year = {2016}, abstract = {Compared to their inorganic counterparts, organic semiconductors suffer from relatively low charge carrier mobilities. Therefore, expressions derived for inorganic solar cells to correlate characteristic performance parameters to material properties are prone to fail when applied to organic devices. This is especially true for the classical Shockley-equation commonly used to describe current-voltage (JV)-curves, as it assumes a high electrical conductivity of the charge transporting material. Here, an analytical expression for the JV-curves of organic solar cells is derived based on a previously published analytical model. This expression, bearing a similar functional dependence as the Shockley-equation, delivers a new figure of merit α to express the balance between free charge recombination and extraction in low mobility photoactive materials. This figure of merit is shown to determine critical device parameters such as the apparent series resistance and the fill factor.}, language = {en} } @article{JannaschNickelBergmannetal.2022, author = {Jannasch, Franziska and Nickel, Daniela V. and Bergmann, Manuela M. and Schulze, Matthias Bernd}, title = {A new evidence-based diet score to capture associations of food consumption and chronic disease risk}, series = {Nutrients / Molecular Diversity Preservation International (MDPI)}, volume = {14}, journal = {Nutrients / Molecular Diversity Preservation International (MDPI)}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {2072-6643}, doi = {10.3390/nu14112359}, pages = {16}, year = {2022}, abstract = {Previously, the attempt to compile German dietary guidelines into a diet score was predominantly not successful with regards to preventing chronic diseases in the EPIC-Potsdam study. Current guidelines were supplemented by the latest evidence from systematic reviews and expert papers published between 2010 and 2020 on the prevention potential of food groups on chronic diseases such as type 2 diabetes, cardiovascular diseases and cancer. A diet score was developed by scoring the food groups according to a recommended low, moderate or high intake. The relative validity and reliability of the diet score, assessed by a food frequency questionnaire, was investigated. The consideration of current evidence resulted in 10 key food groups being preventive of the chronic diseases of interest. They served as components in the diet score and were scored from 0 to 1 point, depending on their recommended intake, resulting in a maximum of 10 points. Both the reliability (r = 0.53) and relative validity (r = 0.43) were deemed sufficient to consider the diet score as a stable construct in future investigations. This new diet score can be a promising tool to investigate dietary intake in etiological research by concentrating on 10 key dietary determinants with evidence-based prevention potential for chronic diseases.}, language = {en} } @article{YuanBraunGueritetal.2019, author = {Yuan, Xiaoping P. and Braun, Jean and Guerit, Laure and Rouby, D. and Cordonnier, G.}, title = {A New Efficient Method to Solve the Stream Power Law Model Taking Into Account Sediment Deposition}, series = {Journal of geophysical research : Earth surface}, volume = {124}, journal = {Journal of geophysical research : Earth surface}, number = {6}, publisher = {American Geophysical Union}, address = {Washington}, issn = {2169-9003}, doi = {10.1029/2018JF004867}, pages = {1346 -- 1365}, year = {2019}, abstract = {The stream power law model has been widely used to represent erosion by rivers but does not take into account the role played by sediment in modulating erosion and deposition rates. Davy and Lague (2009, ) provide an approach to address this issue, but it is computationally demanding because the local balance between erosion and deposition depends on sediment flux resulting from net upstream erosion. Here, we propose an efficient (i.e., O(N) and implicit) method to solve their equation. This means that, unlike other methods used to study the complete dynamics of fluvial systems (e.g., including the transition from detachment-limited to transport-limited behavior), our method is unconditionally stable even when large time steps are used. We demonstrate its applicability by performing a range of simulations based on a simple setup composed of an uplifting region adjacent to a stable foreland basin. As uplift and erosion progress, the mean elevations of the uplifting relief and the foreland increase, together with the average slope in the foreland. Sediments aggrade in the foreland and prograde to reach the base level where sediments are allowed to leave the system. We show how the topography of the uplifting relief and the stratigraphy of the foreland basin are controlled by the efficiency of river erosion and the efficiency of sediment transport by rivers. We observe the formation of a steady-state geometry in the uplifting region, and a dynamic steady state (i.e., autocyclic aggradation and incision) in the foreland, with aggradation and incision thicknesses up to tens of meters.}, language = {en} } @article{Schmidt1997, author = {Schmidt, Hans-J{\"u}rgen}, title = {A new duality transformation for fouth-order gravity}, year = {1997}, language = {en} } @article{KellerMuench2019, author = {Keller, Matthias and M{\"u}nch, Florentin}, title = {A new discrete Hopf-Rinow theorem}, series = {Discrete Mathematics}, volume = {342}, journal = {Discrete Mathematics}, number = {9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0012-365X}, doi = {10.1016/j.disc.2019.03.014}, pages = {2751 -- 2757}, year = {2019}, abstract = {We prove a version of the Hopf-Rinow theorem with respect to path metrics on discrete spaces. The novel aspect is that we do not a priori assume local finiteness but isolate a local finiteness type condition, called essentially locally finite, that is indeed necessary. As a side product we identify the maximal weight, called the geodesic weight, generating the path metric in the situation when the space is complete with respect to any of the equivalent notions of completeness proven in the Hopf-Rinow theorem. As an application we characterize the graphs for which the resistance metric is a path metric induced by the graph structure.}, language = {en} } @article{Richter1995, author = {Richter, Peter}, title = {A new deterministic approach for the optimization of cable layouts for power supply systems}, year = {1995}, language = {en} } @article{SaposhnikovMorosovSaposhnikovetal.1998, author = {Saposhnikov, V. V. and Morosov, Andrej and Saposhnikov, Vl. V. and G{\"o}ssel, Michael}, title = {A new design method for self-checking unidirectional combinational circuits}, year = {1998}, language = {en} } @article{RaschSchindler2005, author = {Rasch, T. and Schindler, R.}, title = {A new condensation principle}, issn = {1432-0665}, year = {2005}, abstract = {We generalize del(A), which was introduced in [Schinfinity], to larger cardinals. For a regular cardinal kappa>N-0 we denote by del(kappa)(A) the statement that Asubset of or equal tokappa and for all regular theta>kappa(o), {X is an element of[L-theta[A]](<) : X \&AND; \&ISIN; \&AND; otp (X \&AND; Ord) \&ISIN; Card (L[A\&AND;X\&AND;])} is stationary in [L-[A]](<). It was shown in [Sch\&INFIN;] that \&DEL;(N1) (A) can hold in a set-generic extension of L. We here prove that \&DEL;(N2) (A) can hold in a set-generic extension of L as well. In both cases we in fact get equiconsistency theorems. This strengthens results of [Ra00] and [Ran01]. \&DEL;(N3) () is equivalent with the existence of 0\#}, language = {en} } @article{WessigWawrzinekMoellnitzetal.2011, author = {Wessig, Pablo and Wawrzinek, Robert and Moellnitz, Kristian and Feldbusch, Elvira and Schilde, Uwe}, title = {A new class of fluorescent dyes based on 1,3-benzodioxole and [1,3]-dioxolo[4.5-f]benzodioxole}, series = {Tetrahedron letters}, volume = {52}, journal = {Tetrahedron letters}, number = {46}, publisher = {Elsevier}, address = {Oxford}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2011.09.058}, pages = {6192 -- 6195}, year = {2011}, abstract = {We report on synthesis and photophysical properties of a new class of fluorescent dyes. They are characterized by large Stokes-shifts, long fluorescence lifetimes in organic solvents and a pronounced dependency of the fluorescence lifetime on the solvent polarity. Also worthy of note is the high bleaching stability. To provide access to biochemical and medical applications a series of derivatives were prepared, which exhibit specific reactivity towards different biologically relevant functional groups (carboxylic acids, amines, maleimides, N-hydroxysuccinimide esters). Furthermore, two alkynes were prepared, which could be used in 'Click' chemistry.}, language = {en} } @article{OeztuerkMarwanvonSpechtetal.2018, author = {{\"O}zt{\"u}rk, Ugur and Marwan, Norbert and von Specht, Sebastian and Korup, Oliver and Jensen, J.}, title = {A new centennial sea-level record for Antalya, Eastern Mediterranean}, series = {Journal of geophysical research-oceans}, volume = {123}, journal = {Journal of geophysical research-oceans}, number = {7}, publisher = {American Geophysical Union}, address = {Washington}, issn = {2169-9275}, doi = {10.1029/2018JC013906}, pages = {4503 -- 4517}, year = {2018}, abstract = {Quantitative estimates of sea-level rise in the Mediterranean Basin become increasingly accurate thanks to detailed satellite monitoring. However, such measuring campaigns cover several years to decades, while longer-term sea-level records are rare for the Mediterranean. We used a data archeological approach to reanalyze monthly mean sea-level data of the Antalya-I (1935-1977) tide gauge to fill this gap. We checked the accuracy and reliability of these data before merging them with the more recent records of the Antalya-II (1985-2009) tide gauge, accounting for an eight-year hiatus. We obtain a composite time series of monthly and annual mean sea levels spanning some 75 years, providing the longest record for the eastern Mediterranean Basin, and thus an essential tool for studying the region's recent sea-level trends. We estimate a relative mean sea-level rise of 2.2 ± 0.5 mm/year between 1935 and 2008, with an annual variability (expressed here as the standard deviation of the residuals, σresiduals = 41.4 mm) above that at the closest tide gauges (e.g., Thessaloniki, Greece, σresiduals = 29.0 mm). Relative sea-level rise accelerated to 6.0 ± 1.5 mm/year at Antalya-II; we attribute roughly half of this rate (~3.6 mm/year) to tectonic crustal motion and anthropogenic land subsidence. Our study highlights the value of data archeology for recovering and integrating historic tide gauge data for long-term sea-level and climate studies.}, language = {en} } @article{AkampuriraAkalaDereseetal.2023, author = {Akampurira, Denis and Akala, Hoseah M. and Derese, Solomon and Heydenreich, Matthias and Yenesew, Abiy}, title = {A new C-C linked benzophenathridine-2-quinoline dimer, and the antiplasmodial activity of alkaloids from Zanthoxylum holstzianum}, series = {Natural product research}, volume = {37}, journal = {Natural product research}, number = {13}, publisher = {Taylor \& Francis}, address = {London [u.a.]}, issn = {1478-6419}, doi = {10.1080/14786419.2022.2034810}, pages = {2161 -- 2171}, year = {2023}, abstract = {The CH2Cl2/MeOH (1:1) extract of Zanthoxylum holstzianum stem bark showed good antiplasmodial activity (IC50 2.5 +/- 0.3 and 2.6 +/- 0.3 mu g/mL against the W2 and D6 strains of Plasmodium falciparum, respectively). From the extract five benzophenanthridine alkaloids [8-acetonyldihydrochelerythrine (1), nitidine (2), dihydrochelerythine (3), norchelerythrine (5), arnottianamide (8)]; a 2-quinolone alkaloid [N-methylflindersine (4)]; a lignan [4,4 '-dihydroxy-3,3 '-dimethoxylignan-9,9 '-diyl diacetate (7)] and a dimer of a benzophenanthridine and 2-quinoline [holstzianoquinoline (6)] were isolated. The CH2Cl2/MeOH (1:1) extract of the root bark afforded 1, 3-6, 8, chelerythridimerine (9) and 9-demethyloxychelerythrine (10). Holstzianoquinoline (6) is new, and is the second dimer linked by a C-C bond of a benzophenanthridine and a 2-quinoline reported thus far. The compounds were identified based on spectroscopic evidence. Amongst five compounds (1-5) tested against two strains of P. falciparum, nitidine (IC50 0.11 +/- 0.01 mu g/mL against W2 and D6 strains) and norchelerythrine (IC50 value of 0.15 +/- 0.01 mu g/mL against D6 strain) were the most active.}, language = {en} } @article{SimonCarbreraKliegl1993, author = {Simon, Tony and Carbrera, Angel and Kliegl, Reinhold}, title = {A new approach to the study of subitizing as distinct enumeration processing}, isbn = {0-8058- 1487-6}, year = {1993}, language = {en} } @article{HedayatMahmoudiSchulze2018, author = {Hedayat Mahmoudi, Mahdi and Schulze, Bert-Wolfgang}, title = {A new approach to the second order edge calculus}, series = {Journal of pseudo-differential operators and applications}, volume = {9}, journal = {Journal of pseudo-differential operators and applications}, number = {2}, publisher = {Springer}, address = {Basel}, issn = {1662-9981}, doi = {10.1007/s11868-017-0191-2}, pages = {265 -- 300}, year = {2018}, abstract = {We establish essential steps of an iterative approach to operator algebras, ellipticity and Fredholm property on stratified spaces with singularities of second order. We cover, in particular, corner-degenerate differential operators. Our constructions are focused on the case where no additional conditions of trace and potential type are posed, but this case works well and will be considered in a forthcoming paper as a conclusion of the present calculus.}, language = {en} } @article{KothaCottonBindi2018, author = {Kotha, Sreeram Reddy and Cotton, Fabrice and Bindi, Dino}, title = {A new approach to site classification}, series = {Soil Dynamics and Earthquake Engineering}, volume = {110}, journal = {Soil Dynamics and Earthquake Engineering}, publisher = {Elsevier}, address = {Oxford}, issn = {0267-7261}, doi = {10.1016/j.soildyn.2018.01.051}, pages = {318 -- 329}, year = {2018}, abstract = {With increasing amount of strong motion data, Ground Motion Prediction Equation (GMPE) developers are able to quantify empirical site amplification functions (delta S2S(s)) from GMPE residuals, for use in site-specific Probabilistic Seismic Hazard Assessment. In this study, we first derive a GMPE for 5\% damped Pseudo Spectral Acceleration (g) of Active Shallow Crustal earthquakes in Japan with 3.4 <= M-w <= 7.3 and 0 <= R-JB <= 600km. Using k-mean spectral clustering technique, we then classify our estimated delta S2S(s)(T = 0.01 - 2s) of 588 wellcharacterized sites, into 8 site clusters with distinct mean site amplification functions, and within-cluster site-tosite variability similar to 50\% smaller than the overall dataset variability (phi(S2S)). Following an evaluation of existing schemes, we propose a revised data-driven site classification characterized by kernel density distributions of V-s30, V-s10, H-800, and predominant period (T-G) of the site clusters.}, language = {en} } @article{BelovaShchukinGorinetal.2011, author = {Belova, Valentina and Shchukin, Dmitry G. and Gorin, Dmitry A. and Kopyshev, Alexey and Moehwald, Helmuth}, title = {A new approach to nucleation of cavitation bubbles at chemically modified surfaces}, series = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, volume = {13}, journal = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, number = {17}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/c1cp20218a}, pages = {8015 -- 8023}, year = {2011}, abstract = {Cavitation at the solid surface normally begins with nucleation, in which defects or assembled molecules located at a liquid-solid interface act as nucleation centers and are actively involved in the evolution of cavitation bubbles. Here, we propose a simple approach to evaluate the behavior of cavitation bubbles formed under high intensity ultrasound (20 kHz, 51.3 W cm (2)) at solid surfaces, based on sonication of patterned substrates with a small roughness (less than 3 nm) and controllable surface energy. A mixture of octadecylphosphonic acid (ODTA) and octadecanethiol (ODT) was stamped on the Si wafer coated with different thicknesses of an aluminium layer (20-500 nm). We investigated the growth mechanism of cavitation bubble nuclei and the evolution of individual pits (defects) formed under sonication on the modified surface. A new activation behavior as a function of Al thickness, sonication time, ultrasonic power and temperature is reported. In this process cooperativity is introduced, as initially formed pits further reduce the energy to form bubbles. Furthermore, cavitation on the patterns is a controllable process, where up to 40-50 min of sonication time only the hydrophobic areas are active nucleation sites. This study provides a convincing proof of our theoretical approach on nucleation.}, language = {en} } @article{SaguTchewonpiHuschekBoenicketal.2019, author = {Sagu Tchewonpi, Sorel and Huschek, Gerd and B{\"o}nick, Josephine and Homann, Thomas and Rawel, Harshadrai Manilal}, title = {A New Approach of Extraction of α-Amylase/trypsin Inhibitors from Wheat (Triticum aestivum L.), Based on Optimization Using Plackett-Burman and Box-Behnken Designs}, series = {molecules}, volume = {24}, journal = {molecules}, number = {19}, publisher = {MDPI}, address = {Basel}, issn = {1420-3049}, doi = {10.3390/molecules24193589}, pages = {18}, year = {2019}, abstract = {Wheat is one of the most consumed foods in the world and unfortunately causes allergic reactions which have important health effects. The α-amylase/trypsin inhibitors (ATIs) have been identified as potentially allergen components of wheat. Due to a lack of data on optimization of ATI extraction, a new wheat ATIs extraction approach combining solvent extraction and selective precipitation is proposed in this work. Two types of wheat cultivars (Triticum aestivum L.), Julius and Ponticus were used and parameters such as solvent type, extraction time, temperature, stirring speed, salt type, salt concentration, buffer pH and centrifugation speed were analyzed using the Plackett-Burman design. Salt concentration, extraction time and pH appeared to have significant effects on the recovery of ATIs (p < 0.01). In both wheat cultivars, Julius and Ponticus, ammonium sulfate substantially reduced protein concentration and inhibition of amylase activity (IAA) compared to sodium chloride. The optimal conditions with desirability levels of 0.94 and 0.91 according to the Doehlert design were: salt concentrations of 1.67 and 1.22 M, extraction times of 53 and 118 min, and pHs of 7.1 and 7.9 for Julius and Ponticus, respectively. The corresponding responses were: protein concentrations of 0.31 and 0.35 mg and IAAs of 91.6 and 83.3\%. Electrophoresis and MALDI-TOF/MS analysis showed that the extracted ATIs masses were between 10 and 20 kDa. Based on the initial LC-MS/MS analysis, up to 10 individual ATIs were identified in the extracted proteins under the optimal conditions. The positive implication of the present study lies in the quick assessment of their content in different varieties especially while considering their allergenic potential.}, language = {en} } @article{Gohlke1995, author = {Gohlke, Mario}, title = {A new approach for model-based recognition using colour regions}, year = {1995}, language = {en} } @article{SigolaevaEremenkoMakoweretal.1999, author = {Sigolaeva, L. V. and Eremenko, A. V. and Makower, Alexander and Makhaeva, G. F. and Malygin, V. V. and Kurochkin, I. N.}, title = {A new approach for determinitaton of neuropath target esterase activity}, year = {1999}, language = {en} } @article{ThomsonWeber1995, author = {Thomson, M. R. A. and Weber, Bernd}, title = {A new and unusual fauna from the Blaiklock Glacier Group, Shackleton Range}, year = {1995}, language = {en} } @article{PapeWessigBrunner2015, author = {Pape, Simon and Wessig, Pablo and Brunner, Heiko}, title = {A new and environmentally benign synthesis of aroylguanidines using iron trichloride}, series = {RSC Advances}, volume = {5}, journal = {RSC Advances}, number = {123}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2046-2069}, doi = {10.1039/c5ra20869f}, pages = {101408 -- 101411}, year = {2015}, abstract = {A new synthetic approach for the guanylation of aroylthioureas using iron trichloride is presented. Our synthetic method distinguishes itself by benign reaction conditions, low costs and a broad product spectrum. The scope of the reaction and calorimetric studies are described.}, language = {en} } @article{TuGeWangetal.2014, author = {Tu, Rui and Ge, Maorong and Wang, Rongjiang and Walter, Thomas R.}, title = {A new algorithm for tight integration of real-time GPS and strong-motion records, demonstrated on simulated, experimental, and real seismic data}, series = {Journal of seismology}, volume = {18}, journal = {Journal of seismology}, number = {1}, publisher = {Springer}, address = {Dordrecht}, issn = {1383-4649}, doi = {10.1007/s10950-013-9408-x}, pages = {151 -- 161}, year = {2014}, abstract = {The complementary advantages of GPS and seismic measurements are well recognized in seismotectonic monitoring studies. Therefore, integrated processing of the two data streams has been proposed recently in an attempt to obtain accurate and reliable information of surface displacements associated with earthquakes. A hitherto still critical issue in the integrated processing is real-time detection and precise estimation of the transient baseline error in the seismic records. Here, we report on a new approach by introducing the seismic acceleration corrected by baseline errors into the state equation system. The correction is performed and regularly updated in short epochs (with increments which may be as short as seconds), so that station position, velocity, and acceleration can be constrained very tightly and baseline error can be estimated as a random-walk process. With the adapted state equation system, our study highlights the use of a new approach developed for integrated processing of GPS and seismic data by means of sequential least-squares adjustment. The efficiency of our approach is demonstrated and validated using simulated, experimental, and real datasets. The latter were collected at collocated GPS and seismic stations around the 4 April 2010, E1 Mayor-Cucapah earthquake (Mw, 7.2). The results have shown that baseline errors of the strong-motion sensors are corrected precisely and high-precision seismic displacements are real-timely obtained by the new approach.}, language = {en} } @article{MeriauWartenburgerKazzeretal.2006, author = {M{\´e}riau, Katja and Wartenburger, Isabell and Kazzer, Philipp and Prehn, Kristin and Lammers, Claas-Hinrich and van der Meer, Elke and Villringer, Arno and Heekeren, Hauke R.}, title = {A neural network reflecting individual differences in cognitive processing of emotions during perceptual decision making}, issn = {1053-8119}, year = {2006}, language = {en} } @article{RheinwahltGoswamiBookhagen2019, author = {Rheinwahlt, Aljoscha and Goswami, Bedartha and Bookhagen, Bodo}, title = {A network-based flow accumulation algorithm for point clouds}, series = {Journal of geophysical research : Earth surface}, volume = {124}, journal = {Journal of geophysical research : Earth surface}, number = {7}, publisher = {American Geophysical Union}, address = {Washington}, issn = {2169-9003}, doi = {10.1029/2018JF004827}, pages = {2013 -- 2033}, year = {2019}, abstract = {Flow accumulation algorithms estimate the steady state of flow on real or modeled topographic surfaces and are crucial for hydrological and geomorphological assessments, including delineation of river networks, drainage basins, and sediment transport processes. Existing flow accumulation algorithms are typically designed to compute flows on regular grids and are not directly applicable to arbitrarily sampled topographic data such as lidar point clouds. In this study we present a random sampling scheme that generates homogeneous point densities, in combination with a novel flow path tracing approach-the Facet-Flow Network (FFN)-that estimates flow accumulation in terms of specific catchment area (SCA) on triangulated surfaces. The random sampling minimizes biases due to spatial sampling and the FFN allows for direct flow estimation from point clouds. We validate our approach on a Gaussian hill surface and study the convergence of its SCA compared to the analytical solution. Here, our algorithm outperforms the multiple flow direction algorithm, which is optimized for divergent surfaces. We also compute the SCA of a 6-km(2)-steep, vegetated catchment on Santa Cruz Island, California, based on airborne lidar point-cloud data. Point-cloud-based SCA values estimated by our method compare well with those estimated by the D-infinity or multiple flow direction algorithm on gridded data. The advantage of computing SCA from point clouds becomes relevant especially for divergent topography and for small drainage areas: These are depicted with much more detail due to the higher sampling density of point clouds.}, language = {en} } @article{MolnosMamdouhPetrietal.2017, author = {Molnos, Sonja and Mamdouh, Tarek and Petri, Stefan and Nocke, Thomas and Weinkauf, Tino and Coumou, Dim}, title = {A network-based detection scheme for the jet stream core}, series = {Earth system dynamics}, volume = {8}, journal = {Earth system dynamics}, number = {1}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {2190-4979}, doi = {10.5194/esd-8-75-2017}, pages = {75 -- 89}, year = {2017}, abstract = {The polar and subtropical jet streams are strong upper-level winds with a crucial influence on weather throughout the Northern Hemisphere midlatitudes. In particular, the polar jet is located between cold arctic air to the north and warmer subtropical air to the south. Strongly meandering states therefore often lead to extreme surface weather. The parameter values of the detection scheme are optimized using simulated annealing and a skill function that accounts for the zonal-mean jet stream position (Rikus, 2015). After the successful optimization process, we apply our scheme to reanalysis data covering 1979-2015 and calculate seasonal-mean probabilistic maps and trends in wind strength and position of jet streams. We present longitudinally defined probability distributions of the positions for both jets for all on the Northern Hemisphere seasons. This shows that winter is characterized by two well-separated jets over Europe and Asia (ca. 20 degrees W to 140 degrees E). In contrast, summer normally has a single merged jet over the western hemisphere but can have both merged and separated jet states in the eastern hemisphere.}, language = {en} } @article{OzturkMalikCheungetal.2019, author = {Ozturk, Ugur and Malik, Nishant and Cheung, Kevin and Marwan, Norbert and Kurths, J{\"u}rgen}, title = {A network-based comparative study of extreme tropical and frontal storm rainfall over Japan}, series = {Climate dynamics : observational, theoretical and computational research on the climate system}, volume = {53}, journal = {Climate dynamics : observational, theoretical and computational research on the climate system}, number = {1-2}, publisher = {Springer}, address = {New York}, issn = {0930-7575}, doi = {10.1007/s00382-018-4597-1}, pages = {521 -- 532}, year = {2019}, abstract = {Frequent and intense rainfall events demand innovative techniques to better predict the extreme rainfall dynamics. This task requires essentially the assessment of the basic types of atmospheric processes that trigger extreme rainfall, and then to examine the differences between those processes, which may help to identify key patterns to improve predictive algorithms. We employ tools from network theory to compare the spatial features of extreme rainfall over the Japanese archipelago and surrounding areas caused by two atmospheric processes: the Baiu front, which occurs mainly in June and July (JJ), and the tropical storms from August to November (ASON). We infer from complex networks of satellite-derived rainfall data, which are based on the nonlinear correlation measure of event synchronization. We compare the spatial scales involved in both systems and identify different regions which receive rainfall due to the large spatial scale of the Baiu and tropical storm systems. We observed that the spatial scales involved in the Baiu driven rainfall extremes, including the synoptic processes behind the frontal development, are larger than tropical storms, which even have long tracks during extratropical transitions. We further delineate regions of coherent rainfall during the two seasons based on network communities, identifying the horizontal (east-west) rainfall bands during JJ over the Japanese archipelago, while during ASON these bands align with the island arc of Japan.}, language = {en} } @article{ChaabeneNegraCapranicaetal.2019, author = {Chaabene, Helmi and Negra, Yassine and Capranica, Laura and Prieske, Olaf and Granacher, Urs}, title = {A Needs Analysis of Karate Kumite With Recommendations for Performance Testing and Training}, series = {Strength and conditioning journal}, volume = {41}, journal = {Strength and conditioning journal}, number = {3}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {1524-1602}, doi = {10.1519/SSC.0000000000000445}, pages = {35 -- 46}, year = {2019}, abstract = {An effective training program needs to be customized to the specific demands of the redpective sport. Therefore, it is important to conduct a needs analysis to gain information on the unique characteristics of the sport. The objectives of thes review were (A) to conduct a systematic needs analysis of karate kumite and (B) to provide practical recommendations for sport-specific performance testing and training of karate kumite athletes.}, language = {en} } @article{CampbellSchultheissMcClelland1999, author = {Campbell, Kenneth L. and Schultheiss, Oliver and McClelland, David C.}, title = {A necessary adjustment of protocol for use of DPC Coat-a-Count Total Testosterone assay with saliva}, year = {1999}, language = {en} } @article{NavarroOrejasPinoetal.2021, author = {Navarro, Marisa and Orejas, Fernando and Pino, Elvira and Lambers, Leen}, title = {A navigational logic for reasoning about graph properties}, series = {Journal of logical and algebraic methods in programming}, volume = {118}, journal = {Journal of logical and algebraic methods in programming}, publisher = {Elsevier Science}, address = {Amsterdam [u.a.]}, issn = {2352-2208}, doi = {10.1016/j.jlamp.2020.100616}, pages = {33}, year = {2021}, abstract = {Graphs play an important role in many areas of Computer Science. In particular, our work is motivated by model-driven software development and by graph databases. For this reason, it is very important to have the means to express and to reason about the properties that a given graph may satisfy. With this aim, in this paper we present a visual logic that allows us to describe graph properties, including navigational properties, i.e., properties about the paths in a graph. The logic is equipped with a deductive tableau method that we have proved to be sound and complete.}, language = {en} } @article{KummerowKindOnckenetal.2004, author = {Kummerow, J. and Kind, Rainer and Oncken, Onno and Giese, Peter and Ryberg, Trond and Wylegalla, Kurt and Scherbaum, Frank}, title = {A natural and controlled source seismic profile through the Eastern Alps : TRANSALP}, year = {2004}, abstract = {The combined passive and active seismic TRANSALP experiment produced an unprecedented high-resolution crustal image of the Eastern Alps between Munich and Venice. The European and Adriatic Mohos (EM and AM, respectively) are clearly imaged with different seismic techniques: near-vertical incidence reflections and receiver functions (RFs). The European Moho dips gently southward from 35 km beneath the northern foreland to a maximum depth of 55 km beneath the central part of the Eastern Alps, whereas the Adriatic Moho is imaged primarily by receiver functions at a relatively constant depth of about 40 km. In both data sets, we have also detected first-order Alpine shear zones, such as the Helvetic detachment, Inntal fault and SubTauern ramp in the north. Apart from the Valsugana thrust, receiver functions in the southern part of the Eastern Alps have also observed a north dipping interface, which may penetrate the entire Adriatic crust [Adriatic Crust Interface (ACI)]. Deep crustal seismicity may be related to the ACI. We interpret the ACI as the currently active retroshear zone in the doubly vergent Alpine collisional belt. (C) 2004 Elsevier B.V. All rights reserved}, language = {en} } @article{BroekerLueckePerpeetetal.2012, author = {Broeker, Patrick and Luecke, Klaus and Perpeet, Markus and Gronewold, Thomas M. A.}, title = {A nanostructured SAW chip-based biosensor detecting cancer cells}, series = {SENSORS AND ACTUATORS B-CHEMICAL}, volume = {165}, journal = {SENSORS AND ACTUATORS B-CHEMICAL}, number = {1}, publisher = {ELSEVIER SCIENCE SA}, address = {LAUSANNE}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.11.022}, pages = {1 -- 6}, year = {2012}, abstract = {A nanostructured chip surface was fabricated enabling binding via spaced antibodies specifically targeting surface proteins of cancer cells and detection of extremely low numbers of circulating tumor cells (CTC) without labeling using a sam (R) 5 biosensor. The antibody surfaces mostly were generated by self assembly of antibodies to gold nanospots on the sensitive SiO2-surface of a sam (R) 5 chip. Compared with a complete gold surface, only 40\% of the amount of antibodies was bound to the nanospot surface, but structured such that 15-fold higher sensitivity to vital cancer cells was achieved. Human cancer cell lines JEG-3 (lmphoblastic leukemia) and MOLT-17 (placental choriocarcinoma) from cell cultures were successfully detected. The sensor showed significant responses on less than 10 cells injected in a single run. The extreme increase in sensitivity and its simple regeneration emphasizes the usefulness of its introduction in biomedical applications. (C) 2011 Elsevier B.V. All rights reserved.}, language = {en} } @article{KietzkeNeherKumkeetal.2004, author = {Kietzke, Thomas and Neher, Dieter and Kumke, Michael Uwe and Montenegro, Rivelino V. D. and Landfester, Katharina and Scherf, Ullrich}, title = {A nanoparticle approach to control the phase separation in polyfluorene photovoltaic devices}, year = {2004}, abstract = {Polymer solar cell devices with nanostructured blend layers have been fabricated using single- and dual- component polymer nanospheres. Starting from an electron-donating and an electron-accepting polyfluorene derivative, PFB and F8BT, dissolved in suitable organic solvents, dispersions of solid particles with mean diameters of ca. 50 nm, containing either the pure polymer components or a mixture of PFB and F8BT in each particle, were prepared with the miniemulsion process. Photovoltaic devices based on these particles have been studied with respect to the correlation between external quantum efficiency and layer composition. It is shown that the properties of devices containing a blend of single-component PFB and F8BT particles differ significantly from those of solar cells based on blend particles, even for the same layer composition. Various factors determining the quantum efficiency in both kinds of devices are identified and discussed, taking into account the spectroscopic properties of the particles. An external quantum efficiency of ca. 4\% is measured for a device made from polymer blend nanoparticles containing PFB:F8BT at a weight ratio of 1:2 in each individual nanosphere. This is among the highest values reported so far for photovoltaic cells using this material combination}, language = {en} }