@phdthesis{Apodiakou2024, author = {Apodiakou, Anastasia}, title = {Analysis of the regulation of SDI genes, unravelling the role of the SLIM1 transcription factor, and the SNRK3.15 kinase in Arabidopsis under sulfur deprivation}, school = {Universit{\"a}t Potsdam}, pages = {141}, year = {2024}, language = {en} } @phdthesis{Seerangan2023, author = {Seerangan, Kumar}, title = {Actin-based regulation of cell and tissue scale morphologenesis in develpoping leaves}, school = {Universit{\"a}t Potsdam}, pages = {120}, year = {2023}, language = {en} } @phdthesis{Benz2024, author = {Benz, Eleanor}, title = {The advisory function of the Inter-American Court of Human Rights}, series = {Beitr{\"a}ge zum ausl{\"a}ndischen {\"o}ffentlichen Recht und V{\"o}lkerrecht}, volume = {329}, journal = {Beitr{\"a}ge zum ausl{\"a}ndischen {\"o}ffentlichen Recht und V{\"o}lkerrecht}, publisher = {Nomos}, address = {Baden-Baden}, issn = {978-3-7489-1980-3}, doi = {10.5771/9783748919803}, school = {Universit{\"a}t Potsdam}, pages = {478}, year = {2024}, abstract = {How do the rights of same-sex couples have to be ensured by states, and which kind of environmental obligations are induced by the right to life and to personal integrity? Questions as diverse and far-reaching as these are regularly dealt with by the Inter-American Court of Human Rights in its advisory function. This book is the first comprehensive, non-Spanish-written treatise on the advisory function of this Court. It analyzes the scope of the Court's advisory jurisdiction and its procedural practice in comparison with that of other international courts. Moreover, the legal effects of the Court's advisory opinions and the question when the Court should better reject a request for an advisory opinion are examined.}, language = {en} } @phdthesis{Duchrau2024, author = {Duchrau, Georg}, title = {M{\"o}glichkeiten und Grenzen des erweiterten Cross Parity Codes}, school = {Universit{\"a}t Potsdam}, pages = {93}, year = {2024}, language = {de} } @phdthesis{Jahns2024, author = {Jahns, Esther}, title = {Diglossic translanguaging}, series = {Language and Social Life [LSL]}, volume = {33}, journal = {Language and Social Life [LSL]}, publisher = {de Gruyter Mouton}, address = {Berlin}, isbn = {978-3-11-132246-9}, doi = {10.1515/9783111322674}, school = {Universit{\"a}t Potsdam}, pages = {XI, 245}, year = {2024}, abstract = {This book examines how German-speaking Jews living in Berlin make sense and make use of their multilingual repertoire. With a focus on lexical variation, the book demonstrates how speakers integrate Yiddish and Hebrew elements into German for indexing belonging and for positioning themselves within the Jewish community. Linguistic choices are shaped by language ideologies (e.g., authenticity, prescriptivism, nostalgia). Speakers translanguage when using their multilingual repertoire, but do so in a diglossic way, using elements from different languages for specific domains}, language = {en} } @phdthesis{BierbrauerzuBrennstein2024, author = {Bierbrauer zu Brennstein, Sophie-Charlotte von}, title = {Die Juristenausbildung in der SBZ-DDR als System durchgeformter Kontrolle}, series = {Schriften zur Rechtsgeschichte}, volume = {221}, journal = {Schriften zur Rechtsgeschichte}, publisher = {Duncker \& Humblot}, address = {Berlin}, isbn = {978-3-428-19054-6}, doi = {10.3790/978-3-428-59054-4}, pages = {377}, year = {2024}, abstract = {Law Studies in the SBZ/GDR as a System of Organized Control. Evaluation of Sources with Special Consideration of the Selection, Education and Further Training of Public Prosecutors«: Using the original sources kept in the Federal Archives, this work examines the requirements placed on law studies in the GDR and the circumstances under which legal training took place. The analysis of the archive material leads to the conclusion that the education and training of GDR lawyers was determined by a systematic political-ideological education and control to ensure the goals of the socialist party.}, language = {de} } @phdthesis{Rinne2024, author = {Rinne, Theresa Charlotte}, title = {The effects of nutrients on bone stem cell function and regeneration}, school = {Universit{\"a}t Potsdam}, pages = {V, 134}, year = {2024}, abstract = {Aging is associated with bone loss, which can lead to osteoporosis and high fracture risk. This coincides with the enhanced formation of bone marrow adipose tissue (BMAT), suggesting a negative effect of bone marrow adipocytes on skeletal health. Increased BMAT formation is also observed in pathologies such as obesity, type 2 diabetes and osteoporosis. However, a subset of bone marrow adipocytes forming the constitutive BMAT (cBMAT), arise early in life in the distal skeleton, contain high levels of unsaturated fatty acids and are thought to provide a physiological function. Regulated BMAT (rBMAT) forms during aging and obesity in proximal regions of the bone and contain a large proportion of saturated fatty acids. Paradoxically, BMAT accumulation is also enhanced during caloric restriction (CR), a life-span extending dietary intervention. This indicates, that different types of BMAT can form in response to opposing nutritional stimuli with potentially different functions. To this end, two types of nutritional interventions, CR and high fat diet (HFD), that are both described to induce BMAT accumulation were carried out. CR markedly increased BMAT formation in the proximal tibia and led to a higher proportion of unsaturated fatty acids, making it similar to the physiological cBMAT. Additionally, proximal and diaphyseal tibia regions displayed higher adiponectin expression. In aged mice, CR was associated with an improved trabecular bone structure. Taken together, these findings demonstrate, that the type of BMAT that forms during CR might provide beneficial effects for local bone stem/progenitor cells and metabolic health. The HFD intervention performed in this thesis showed no effect on BMAT accumulation and bone microstructure. RNA Seq analysis revealed alterations in the composition of the collagen-containing extracellular matrix (ECM). In order to investigate the effects of glucose homeostasis on osteogenesis, differentiation capacity of immortalized multipotent mesenchymal stromal cells (MSCs) and osteochondrogenic progenitor cells (OPCs) was analyzed. Insulin improved differentiation in both cell types, however, combination of with a high glucose concentration led to an impaired mineralization of the ECM. In the MSCs, this was accompanied by the formation of adipocytes, indicating negative effects of the adipocytes formed during hyperglycemic conditions on mineralization processes. However, the altered mineralization pattern and structure of the ECM was also observed in OPCs, which did not form any adipocytes, suggesting further negative effects of a hyperglycemic environment on osteogenic differentiation. In summary, the work provided in this thesis demonstrated that differentiation commitment of bone-resident stem cells can be altered through nutrient availability, specifically glucose. Surprisingly, both high nutrient supply, e.g. the hyperglycemic cell culture conditions, and low nutrient supply, e.g. CR, can induce adipogenic differentiation. However, while CR-induced adipocyte formation was associated with improved trabecular bone structure, adipocyte formation in a hyperglycemic cell-culture environment hampered mineralization. This thesis provides further evidence for the existence of different types of BMAT with specific functions.}, language = {en} } @phdthesis{Ronneberger2024, author = {Ronneberger, Sebastian}, title = {Nanolayer Fused Deposition Modeling (NanoFDM)}, school = {Universit{\"a}t Potsdam}, pages = {170}, year = {2024}, language = {en} } @phdthesis{Schuchardt2023, author = {Schuchardt, Konstantin}, title = {Sigismund Stern und die Genossenschaft f{\"u}r Reform}, series = {Potsdamer j{\"u}dische Studien}, volume = {9}, journal = {Potsdamer j{\"u}dische Studien}, publisher = {be.bra wissenschafts Verlag}, address = {Berlin}, isbn = {978-3-95410-290-7}, school = {Universit{\"a}t Potsdam}, pages = {307}, year = {2023}, abstract = {Dieses Buch geht der Frage nach, aus welchen Gr{\"u}nden im Berlin des Jahres 1845 mit der »Genossenschaft f{\"u}r Reform im Judenthum« die wom{\"o}glich bis heute radikalste Auspr{\"a}gung j{\"u}discher Reform entstand. Dazu werden die Hauptwerke Sigismund Sterns (1812-1867), des Gr{\"u}nders der Bewegung, erstmals systematisch dargestellt und zeitgeschichtlich eingeordnet. Die Studie macht deutlich, dass die Gr{\"u}ndung der Genossenschaft nur im Kontext der vielf{\"a}ltigen, gesamtgesellschaftlichen und innerj{\"u}dischen, religi{\"o}sen und politischen Umw{\"a}lzungen im Vorm{\"a}rz und deren theoretisch-diskursivem Unterbau verstanden werden kann. Das Aufkommen der Bewegung und das j{\"a}he Verklingen ihrer Vitalit{\"a}t nach 1848 erweisen sich dabei als Spiegel der komplexen Verflechtungszusammenh{\"a}nge deutsch-j{\"u}dischen philosophisch-theologischen Denkens im 19. Jahrhundert.}, language = {de} } @phdthesis{Jaentsch2024, author = {J{\"a}ntsch, Christian}, title = {Lehrerinnen und Lehrer auf dem Weg zur Inklusion}, publisher = {Julius Klinkhardt}, address = {Bad Heilbrunn}, isbn = {978-3-7815-6095-6}, doi = {10.35468/9783781560956}, school = {Universit{\"a}t Potsdam}, pages = {189}, year = {2024}, language = {de} } @phdthesis{Kanehira2023, author = {Kanehira, Yuya}, title = {Versatile DNA origami based SERS substrates for spectroscopic applications}, pages = {115}, year = {2023}, language = {en} } @phdthesis{RothRawald2023, author = {Roth-Rawald, Julia}, title = {Krankheits{\"a}ngste in verschiedenen Populationen und die Effektivit{\"a}t ambulanter Verhaltenstheraphie}, school = {Universit{\"a}t Potsdam}, pages = {109}, year = {2023}, language = {de} } @phdthesis{Kaneza2024, author = {Kaneza, Elisabeth}, title = {Rassische Diskriminierung in Deutschland}, series = {Schriften des MenschenRechtsZentrums der Universit{\"a}t Potsdam}, volume = {49}, journal = {Schriften des MenschenRechtsZentrums der Universit{\"a}t Potsdam}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-7560-1461-3}, doi = {10.5771/9783748919988}, school = {Universit{\"a}t Potsdam}, pages = {417}, year = {2024}, abstract = {Diese Arbeit zeigt auf, wie historisch und rechtlich eine Ungleichheit zwischen Schwarzen und Weißen in Deutschland gewachsen ist und geht der Frage nach, welche Anforderungen das Verfassungsrecht, die Rechtspraxis und die Politik erf{\"u}llen m{\"u}ssen, um sie auszugleichen. Eingangs wird die Entwicklung des Verbots der rassischen Diskriminierung im internationalen und nationalen Recht dargelegt. Folglich zeichnet die Verfasserin die Diskriminierungsgeschichte von Schwarzen Menschen nach. Zur {\"U}berwindung der nach wie vor bestehenden strukturellen Diskriminierung schl{\"a}gt sie ein positives Recht vor, das sich auf Menschenrechtsstandards und L{\"o}sungsans{\"a}tzen aus Rechtsvergleichen st{\"u}tzt und die Gleichberechtigung von Schwarzen Menschen bewirken soll.}, language = {de} } @phdthesis{Grohmann2024, author = {Grohmann, Nils-Hendrik}, title = {Strengthening the UN Human Rights Treaty Bodies}, series = {Jus Internationale et Europaeum}, journal = {Jus Internationale et Europaeum}, number = {202}, publisher = {Mohr Siebeck}, address = {T{\"u}bingen}, isbn = {978-3-16-162825-2}, issn = {1861-1893}, doi = {10.1628/978-3-16-162826-9}, pages = {XV, 315}, year = {2024}, abstract = {Nils-Hendrik Grohmann besch{\"a}ftigt sich mit dem noch andauernden St{\"a}rkungsprozess der UN-Menschenrechtsvertragsorgane. Er analysiert, welche rechtlichen Befugnisse die Aussch{\"u}sse haben, ob sie von sich aus Vorschl{\"a}ge einbringen k{\"o}nnen und inwieweit sie ihre Verfahrensweisen bisher aufeinander abgestimmt haben. Ein weiterer Schwerpunkt liegt auf der Zusammenarbeit zwischen den verschiedenen Aussch{\"u}ssen und der Frage, welche Rolle das Treffen der Vorsitzenden bei der St{\"a}rkung spielen kann.}, language = {en} } @phdthesis{Tomović2024, author = {Tomović, Jelena}, title = {Sexualit{\"a}t in der Geschichte}, series = {Schriften des Fr{\"u}hneuzeitzentrums Potsdam}, volume = {12}, journal = {Schriften des Fr{\"u}hneuzeitzentrums Potsdam}, publisher = {V\&R unipress - Brill Deutschland GmbH}, address = {G{\"o}ttingen}, isbn = {978-3-8471-1686-8}, issn = {2198-5251}, doi = {10.14220/9783737016865}, school = {Universit{\"a}t Potsdam}, pages = {336}, year = {2024}, abstract = {Jelena Tomović f{\"u}hrt in diesem Band durch die Entwicklungen unserer sexuellen Sprache und Praktiken. Sie zeigt, dass die Art und Weise, wie {\"u}ber Sexualit{\"a}t gesprochen wird, nicht nur ein Spiegelbild, sondern auch ein treibender Faktor f{\"u}r soziale Ver{\"a}nderungen ist. Die Studie stellt die konventionelle Vorstellung von Sexualit{\"a}t in Frage und f{\"u}hrt die Lesenden in eine Welt der subtilen Nuancen und kulturellen Ver{\"a}nderungen. Mit kommunikationstheoretischen Ans{\"a}tzen, dem praxeologischen Ansatz, ihrer sozialkonstruktivistischen Grundannahme und einem klaren Fokus auf Akteur*innen bietet die Autorin eine frische Perspektive auf die Geschichte der Sexualit{\"a}t. Das Buch er{\"o}ffnet neue Wege f{\"u}r die Erforschung und das Verst{\"a}ndnis von Intimit{\"a}t und sozialer Kommunikation.}, language = {de} } @phdthesis{Henning2024, author = {Henning, Thorsten}, title = {Cross-sectional associations of dietary biomarker patterns with health and nutritional status}, school = {Universit{\"a}t Potsdam}, pages = {111}, year = {2024}, language = {en} } @phdthesis{Martin2024, author = {Martin, Katja}, title = {Beerdigen oder verbrennen?}, publisher = {arijeh-verlag}, address = {Potsdam}, isbn = {978-3-944693-04-0}, school = {Universit{\"a}t Potsdam}, pages = {398}, year = {2024}, language = {de} } @phdthesis{Kersting2024, author = {Kersting, Katerina}, title = {Development of a CRISPR/Cas gene editing technique for the coccolithophore Chrysotila carterae}, school = {Universit{\"a}t Potsdam}, pages = {137}, year = {2024}, language = {en} } @phdthesis{Stechemesser2023, author = {Stechemesser, Annika}, title = {Human behaviour in a warming world}, school = {Universit{\"a}t Potsdam}, pages = {339}, year = {2023}, language = {en} } @phdthesis{Rehtmeyer2024, author = {Rehtmeyer, Marcus}, title = {Die Staatskirchenvertr{\"a}ge Preußens 1929 und 1931}, series = {Rechtsgeschichtliche Forschungen}, volume = {4}, journal = {Rechtsgeschichtliche Forschungen}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-7560-1369-2}, school = {Universit{\"a}t Potsdam}, pages = {734}, year = {2024}, abstract = {Die umfangreiche rechtswissenschaftliche Studie befasst sich mit den preußischen Staatskirchenvertr{\"a}gen aus der Zeit der Weimarer Republik. Diese Vertr{\"a}ge waren H{\"o}hepunkte einer Entwicklung in Richtung gr{\"o}ßerer Freiheit und Unabh{\"a}ngigkeit der Kirchen vom Staat, die den Vorg{\"a}ngen im Reich und in anderen deutschen L{\"a}ndern teils entsprach, teils zuwiderlief. Die Entwicklung folgte keiner unverr{\"u}ckbaren Idealvorstellung {\"u}ber das Verh{\"a}ltnis von Staat und Kirche, sondern stellte sich stets als pragmatische Reaktion auf realpolitische Probleme dar. Die Staatskirchenvertr{\"a}ge selbst pr{\"a}gten die weiteren Entwicklungen in Ost und West bis zur Gegenwart.}, language = {de} } @phdthesis{You2024, author = {You, Lili}, title = {Chloroplast engineering for recombinant protein production and stress protection}, school = {Universit{\"a}t Potsdam}, pages = {133}, year = {2024}, language = {en} } @phdthesis{Szekely2024, author = {Sz{\´e}kely, Andr{\´a}s Csaba}, title = {Long-distance circadian coordination via a phloem-delivered mobile transcript}, school = {Universit{\"a}t Potsdam}, pages = {105}, year = {2024}, language = {en} } @phdthesis{Melliger2024, author = {Melliger, Marc Andr{\´e}}, title = {Effects of exposing renewables to the market}, school = {Universit{\"a}t Potsdam}, pages = {xi, 139}, year = {2024}, abstract = {Electricity production contributes to a significant share of greenhouse gas emissions in Europe and is thus an important driver of climate change. To fulfil the Paris Agreement, the European Union (EU) needs a rapid transition to a fully decarbonised power production system. Presumably, such a system will be largely based on renewables. So far, many EU countries have supported a shift towards renewables such as solar and wind power using support schemes, but the economic and political context is changing. Renewables are now cheaper than ever before and have become cost-competitive with conventional technologies. Therefore, European policymakers are striving to better integrate renewables into a competitive market and to increase the cost-effectiveness of the expansion of renewables. The first step was to replace previous fixed-price schemes with competitive auctions. In a second step, these auctions have become more technology-open. Finally, some governments may phase out any support for renewables and fully expose them to the competitive power market. However, such policy changes may be at odds with the need to rapidly expand renewables and meet national targets due to market characteristics and investors' risk perception. Without support, price risks are higher, and it may be difficult to meet an investor's income expectations. Furthermore, policy changes across different countries could have unexpected effects if power markets are interconnected and investors able to shift their investments. Finally, in multi-technology auctions, technologies may dominate, which can be a risk for long-term power system reliability. Therefore, in my thesis, I explore the effects of phasing out support policies for renewables, of coordinating these phase-outs across countries, and of using multi-technology designs. I expand the public policy literature about investment behaviour and policy design as well as policy change and coordination, and I further develop an agent-based model. The main questions of my thesis are what the cost and deployment effects of gradually exposing renewables to market forces would be and how coordination between countries affects investors' decisions and market prices.. In my three contributions to the academic literature, I use different methods and come to the following results. In the first contribution, I use a conjoint analysis and market simulation to evaluate the effects of phasing out support or reintroducing feed-in tariffs from the perspective of investors. I find that a phase-out leads to investment shifts, either to other still-supported technologies or to other countries that continue to offer support. I conclude that the coordination of policy changes avoids such shifts.. In the second contribution, I integrate the empirically-derived preferences from the first contribution in to an agent-based power system model of two countries to simulate the effects of ending auctions for renewables. I find that this slows the energy transition, and that cross-border effects are relevant. Consequently, continued support is necessary to meet the national renewables targets. In the third contribution, I analyse the outcome of past multi-technology auctions using descriptive statistics, regression analysis as well as case study comparisons. I find that the outcomes are skewed towards single technologies. This cannot be explained by individual design elements of the auctions, but rather results from context-specific and country-specific characteristics. Based on this, I discuss potential implications for long-term power system reliability. The main conclusions of my thesis are that a complete phase-out of renewables support would slow down the energy transition and thus jeopardize climate targets, and that multi-technology auctions may pose a risk for some countries, especially those that cannot regulate an unbalanced power plant portfolio in the long term. If policymakers decide to continue supporting renewables, they may consider adopting technology-specific auctions to better steer their portfolio. In contrast, if policymakers still want to phase out support, they should coordinate these policy changes with other countries. Otherwise, overall transition costs can be higher, because investment decisions shift to still-supported but more expensive technologies.}, language = {en} } @phdthesis{Streitboerger2024, author = {Streitb{\"o}rger, Chiara}, title = {Preisalgorithmenkartelle}, series = {Datenrecht und neue Technologien}, volume = {9}, journal = {Datenrecht und neue Technologien}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-7560-0838-4}, school = {Universit{\"a}t Potsdam}, pages = {325}, year = {2024}, abstract = {Mithilfe von Preisalgorithmen sind Unternehmen in der Lage, automatische und wechselseitige Preisanpassungen vorzunehmen. Dadurch k{\"o}nnen klassische Kartellkonstellationen mangels konspirativer Treffen in den Hintergrund treten. Die Arbeit zeigt auf, unter welchen Voraussetzungen der Einsatz von Preisalgorithmen einen Verstoß gegen das europ{\"a}ische Kartellverbot begr{\"u}nden kann. Dazu werden Fallkonstellationen beleuchtet, die ein algorithmisches Zusammenwirken sowohl unmittelbar zwischen Wettbewerbern als auch mittelbar {\"u}ber einen Dritten begr{\"u}nden. Ferner wird auch auf algorithmenspezifische Compliance-Maßnahmen eingegangen. Schließlich werden die praktischen Herausforderungen bei der Aufdeckung und dem Nachweis solcher Kartelle aufgezeigt.}, language = {de} } @phdthesis{Schmidt2023, author = {Schmidt, Christian}, title = {Vom Trauma zum bedeutungsvollen Ersterlebnis}, publisher = {Karl Alber}, address = {Baden-Baden}, isbn = {978-3-4959-9450-4}, doi = {10.5771/9783495994511}, pages = {342}, year = {2023}, abstract = {Ausgehend von {\"U}berlegungen des anthropologisch orientierten Psychiaters Erwin Straus geht dieses Buch der Frage nach, welche Bedingungen vorliegen, wenn bestimmte Ereignisse von Personen als bedeutsam erlebt werden. Des Weiteren wird ausf{\"u}hrlich er{\"o}rtert, wie sich Personalit{\"a}t im Menschen ausbildet und inwieweit sie von der gelingenden Integration bedeutungsvoller Ersterlebnisse abh{\"a}ngt. Das dabei zugrundeliegende Person-Konzept stellt einen eigenst{\"a}ndigen Syntheseversuch der vier Konzepte von Erwin Straus, Viktor Emil von Gebsattel, Helmuth Plessner und Max Scheler dar. Der Autor arbeitet in ober{\"a}rztlicher Funktion am Klinikum Schloss L{\"u}tgenhof in Dassow, einer Akutklinik f{\"u}r Personale Medizin, integrierte Psychosomatik, Innere Medizin und Psychotherapie}, language = {de} } @phdthesis{Wojciechowska2022, author = {Wojciechowska, Izabela}, title = {The journey towards the discovery of new protein-metabolite interactions in Arabidopsis thaliana and further functional characterization of selected binding events}, school = {Universit{\"a}t Potsdam}, pages = {150}, year = {2022}, language = {en} } @phdthesis{Kappel2023, author = {Kappel, Sandrine}, title = {Photosynthesis in fluctuating light}, school = {Universit{\"a}t Potsdam}, pages = {172}, year = {2023}, abstract = {Light is the essential energy source for plants to drive photosynthesis. In nature, light availability is highly variable and often fluctuates on very short time scales. As a result, plants developed mechanisms to cope with these fluctuations. Understanding how to improve light use efficiency in natural fluctuating light (FL) conditions is a major target for agronomy. In the first project, we identified an Arabidopsis thaliana plant that showed reduced levels of rapidly inducible non-photochemical quenching (NPQ). This plant was devoid of any T-DNA insertion. Using a mapping-by-sequencing approach, we successfully located the causal genomic region near the end of chromosome 4. Through variant investigations in that region, we identified a deletion of about 20 kb encompassing 9 genes. By complementation analysis, we confirmed that one of the deleted genes, VTC2, is the causal gene responsible for the low NPQ. Loss of VTC2 decreased NPQ particularly in old leaves, with young leaves being only slightly affected. Additionally, ascorbate levels were almost abolished in old leaves, likely causing the NPQ decrease by reducing the activity of the xanthophyll cycle. Although ascorbate levels in younger leaves were reduced compared to wild-type plants, they remained at a comparably higher level. This difference may be due to the VTC2 paralog VTC5, which is expressed at a higher level in young leaves than in old ones. Plants require the PROTON GRADIENT REGULATION 5 (PGR5) protein for survival in FL. pgr5 mutants die because they fail to increase the luminal proton concentration in response to high light (HL) phases. A rapid elevation in ∆pH is needed to slow down electron transport through the Cytochrome b6 f complex (photosynthetic control). In FL, such lack of control in the pgr5 mutants results in photosystem I (PSI) overreduction, reactive oxygen species (ROS) production, and cell death. Decreases in photosystem II (PSII) activity introduced by crossing pgr5 with PSII deficient mutants rescued the lethality of pgr5 in FL. PGR5 was suggested to act as part of the ferredoxin-plastoquinone reductase (FQR), involved in cyclic electron transfer around PSI. However, the proposed molecular role of PGR5 remains highly debated. To learn more about PGR5 function, we performed a forward genetic screen in Arabidopsis thaliana to identify EMS-induced suppressor mutants surviving longer when grown in FL compared to pgr5 mutants (referred to as "suppressor of pgr5 lethality in fluctuating light", splf ). 11 different candidate genes were identified in a total of 22 splf plants. Mutants of seven of these genes in the pgr5 background showed low Fv/Fm values when grown in non-fluctuating low light (LL). Five of these 4genes were previously reported to have a role in PSII biogenesis or function. Two others, RPH1 and a DEAD/DEAH box helicase (AT3G02060), have not been linked to PSII function before. Three of splf candidate genes link to primary metabolism, fructose-2,6-bisphosphatase (F2KP ), udp-glucose pyrophosphorylase 1 (UGP1 ) and ferredoxin-dependent glutamate synthase (Fd-GOGAT ). They are characterized by the fact that they survive longer in FL than pgr5 mutants but do not procede beyond the early vegetative phase and then die.}, language = {en} } @phdthesis{Bulut2023, author = {Bulut, Mustafa}, title = {Assessing the genetic architecture underlying systemic responses to variable environments in crops using multi-omics}, school = {Universit{\"a}t Potsdam}, pages = {180, IV}, year = {2023}, abstract = {Plant metabolism serves as the primary mechanism for converting assimilated carbon into essential compounds crucial for plant growth and ultimately, crop yield. This renders it a focal point of research with significant implications. Despite notable strides in comprehending the genetic principles underpinning metabolism and yield, there remains a dearth of knowledge regarding the genetic factors responsible for trait variation under varying environmental conditions. Given the burgeoning global population and the advancing challenges posed by climate change, unraveling the intricacies of metabolic and yield responses to water scarcity became increasingly important in safeguarding food security. Our research group has recently started to work on the genetic resources of legume species. To this end, the study presented here investigates the metabolic diversity across five different legume species at a tissue level, identifying species-specific biosynthesis of alkaloids as well as iso-/flavonoids with diverse functional groups, namely prenylation, phenylacylation as well as methoxylation, to create a resource for follow up studies investigation the metabolic diversity in natural diverse populations of legume species. Following this, the second study investigates the genetic architecture of drought-induced changes in a global common bean population. Here, a plethora of quantitative trait loci (QTL) associated with various traits are identified by performing genome-wide association studies (GWAS), including for lipid signaling. On this site, overexpression of candidates highlighted the induction of several oxylipins reported to be pivotal in coping with harsh environmental conditions such as water scarcity. Diverging from the common bean and GWAS, the following study focuses on identifying drought-related QTL in tomato using a bi-parental breeding population. This descriptive study highlights novel multi-omic QTL, including metabolism, photosynthesis as well as fruit setting, some of which are uniquely assigned under drought. Compared to conventional approaches using the bi-parental IL population, the study presented improves the resolution by assessing further backcrossed ILs, named sub-ILs. In the final study, a photosynthetic gene, namely a PetM subunit of the cytochrome b6f complex encoding gene, involved in electron flow is characterized in an horticultural important crop. While several advances have been made in model organisms, this study highlights the transition of this fundamental knowledge to horticultural important crops, such as tomato, and investigates its function under differing light conditions. Overall, the presented thesis combines different strategies in unveiling the genetic components in multi-omic traits under drought using conventional breeding populations as well as a diverse global population. To this end, it allows a comparison of either approach and highlights their strengths and weaknesses.}, language = {en} } @phdthesis{Kern2023, author = {Kern, Anne}, title = {Juana Borrero}, series = {Mimesis}, volume = {93}, journal = {Mimesis}, publisher = {De Gruyter}, address = {Berlin}, isbn = {978-3-11-074835-2}, issn = {0178-7489}, doi = {10.1515/9783110748499}, school = {Universit{\"a}t Potsdam}, pages = {XIII, 602}, year = {2023}, abstract = {Juana Borrero y Pierra (1877-1896) war eine der wichtigsten Vertreterinnen des inselkubanischen Modernismo. Gleichwohl ist das Schaffen der schon zu Lebzeiten zum Wunderkind stilisierten Autorin, Dichterin und Malerin wissenschaftlich kaum eingehender untersucht worden. Die Werkstudie schl{\"a}gt einen umfassenden, konsequent {\"a}sthetischen Blick auf das aus Gedichten, poetischer Prosa, literarischen Liebesbriefen, Zeichnungen und Malereien bestehende Gesamtwerk Borreros vor, das im Kern ein Streben nach Ganzheit von Kunst und Leben offenlegt. Dabei werden die Text- und Bildstrategien der K{\"u}nstlerin mit den {\"a}sthetischen, soziohistorischen und biografischen Kontexten verzahnt, wodurch Juana Borreros Stimme als exemplarische Stimme der kubanischen Sp{\"a}tmoderne sowie einer bewegten kubanischen Literatur les- und sichtbar wird.}, language = {de} } @phdthesis{Maul2023, author = {Maul, Valeska Joya}, title = {Addressing current challenges of ecosystems in innovation and entrepreneuership}, school = {Universit{\"a}t Potsdam}, pages = {176, XX}, year = {2023}, abstract = {Nowadays, innovative and entrepreneurial activities and their actors are embedded in interdependent systems to drive joint value creation. Innovation ecosystems and entrepreneurial ecosystems have become established system-level concepts in management research to explain how value transpires between different actors and institutions in distinct contexts. Despite the popularity of the concepts, researchers have critiqued their theoretical depth, conceptual distinctiveness, as well as operationalization and measurement (Autio \& Thomas, 2022; Klimas \& Czakon, 2022). Furthermore, in light of current-day challenges, research has yet to address how context impacts innovation and entrepreneurial ecosystems and their actors and elements (Wurth et al., 2022). The aim of this cumulative thesis is to provide a deeper understanding of the conceptualization, operationalization, and measurement of innovation and entrepreneurial ecosystems and investigate how contextual factors can influence the overall ecosystem and its key actors. To this end, bibliometric and empirical-qualitative methods, as well as narrative and systematic literature reviews, are employed. After introducing the research scope and key concepts in Chapter 1, a systematic literature review to operationalize and measure the concept of innovation ecosystems is conducted, and an integrative framework of its composition is introduced in Chapter 2. In Chapter 3, the innovation journal network is outlined by means of science mapping to determine current and emerging research areas characterizing innovation studies. In Chapters 4 and 5, the interplay between the temporal context of the Covid-19 pandemic and the spatial context of entrepreneurial ecosystems is assessed by focusing on the role of organizational resilience and affordances. The findings shed new light on the dynamics and boundaries of entrepreneurial ecosystems as they move between the spatial and digital realm. Building on this, an integrative framework of digital entrepreneurial ecosystems is presented in Chapter 6. The concluding Chapter 7 summarizes my thesis's conceptual, theoretical, and empirical insights, highlighting implications, limitations, and promising future research avenues. The findings of this cumulative thesis contribute to the theoretical and conceptual advancement of ecosystems in innovation and entrepreneurship by providing insights into the measurement and operationalization of its elements. Furthermore, the results show that contextual factors, such as crisis events or institutional circumstances, influence innovation and entrepreneurial ecosystems and their actors, calling for a more nuanced consideration of ecosystem configurations and dynamics. By drawing from the theory of affordances, the elements that actually afford value to the actors and how they shift between the physical and digital realm are portrayed. Based on these findings, this thesis introduces novel frameworks and conceptual advancements of the configurations and boundaries of innovation and (digital) entrepreneurial ecosystems, laying the foundation for a renewed understanding of how to design, orchestrate, and evaluate ecosystems today and in the future.}, language = {en} } @phdthesis{Schaumburg2024, author = {Schaumburg, Josephine}, title = {Men are not better negotiators after all!}, series = {Schriftenreihe zum Verhandlungsmanagement}, volume = {24}, journal = {Schriftenreihe zum Verhandlungsmanagement}, publisher = {Kovac}, address = {Hamburg}, isbn = {978-3-339-13798-2}, issn = {2365-7898}, school = {Universit{\"a}t Potsdam}, pages = {284}, year = {2024}, abstract = {This dissertation examines the lack of clarity in the scientific literature regarding gender and negotiation performance. It is often claimed that men negotiate better than women, yet it is simultaneously emphasized that results strongly depend on context. Through the use of qualitative methods such as content analysis and critical mixed-methods review, the research question: "Are women truly inferior negotiators compared to men?" is addressed. The study comprises a descriptive and an interpretive part. The descriptive section illuminates various interpretations of gender-specific negotiation theory among citing authors, with 67\% arguing for a general superiority of men. However, given the high variance in gender-specific differences, the focus should instead be on the context-dependency of negotiation performance. Generalized statements can be made within contexts, but not across them. In the interpretive section, several factors contributing to this misinterpretation are highlighted, including discrepancies in the definition of negotiation performance and distortions in research communication.. From a scientific perspective, this study underscores the need for a nuanced sociological analysis and warns against the one-sided acceptance of inaccurate scientific interpretations. From a practical standpoint, it amplifies the voices of women affected by biased research paradigms. Overall, the dissertation clarifies the theory of gender-specific negotiation performance and advocates for the elimination of biases in scientific discourse.}, language = {en} } @phdthesis{Schuster2023, author = {Schuster, Josephine}, title = {Der strafrechtliche Schutz rechtlich bemakelter Verm{\"o}genspositionen}, series = {Neue juristische Beitr{\"a}ge}, volume = {142}, journal = {Neue juristische Beitr{\"a}ge}, publisher = {utzverlag}, address = {M{\"u}nchen}, isbn = {978-3-8316-7742-9}, school = {Universit{\"a}t Potsdam}, pages = {312}, year = {2023}, abstract = {Unterliegt illegales Verm{\"o}gen dem strafrechtlichen Verm{\"o}gensschutz? Die Beantwortung dieser Frage ist seit Jahren in der Strafrechtswissenschaft umstritten und f{\"u}hrt zu einer Vielzahl an Meinungen. St{\"a}rken und Schw{\"a}chen der in der Literatur vertretenen Ansichten sind bis heute Gegenstand einer andauernden wissenschaftlichen Diskussion. Dennoch fehlt es an einer umfassenden Untersuchung der h{\"o}chstrichterlichen Rechtsprechungspraxis - diese L{\"u}cke soll die vorliegende Arbeit schließen. Um die F{\"u}lle der daf{\"u}r untersuchten Entscheidungen systematisch darzustellen, wurden diese in verschiedene Fallgruppen eingeordnet. Die Bildung der Fallgruppen basiert nicht wie {\"u}blich auf einem ph{\"a}nomenologischen Ansatz, sondern auf einem konsequenten systematisch-dogmatischen Ansatz. Dies erm{\"o}glicht die Betrachtung bekannter Sachverhaltskonstellationen im neuen Licht.}, language = {de} } @phdthesis{Offizier2024, author = {Offizier, Frederike}, title = {The biosecurity individual}, series = {American Culture Studies}, volume = {43}, journal = {American Culture Studies}, publisher = {Transcript}, address = {Bielefeld}, isbn = {978-3-8376-7145-2}, issn = {2747-4380}, doi = {10.14361/9783839471456}, pages = {294}, year = {2024}, abstract = {Discoveries in biomedicine and biotechnology, especially in diagnostics, have made prevention and (self)surveillance increasingly important in the context of health practices. Frederike Offizier offers a cultural critique of the intersection between health, security and identity, and explores how the focus on risk and security changes our understanding of health and transforms our relationship to our bodies. Analyzing a wide variety of texts, from life writing to fiction, she offers a critical intervention on how this shift in the medical gaze produces new paradigms of difference and new biomedically facilitated identities: biosecurity individuals.}, language = {en} } @phdthesis{Woebbeking2024, author = {W{\"o}bbeking, Cordula}, title = {K{\"o}rper - Karte - Text}, series = {Sanssouci - Forschungen zur Romanistik}, volume = {22}, journal = {Sanssouci - Forschungen zur Romanistik}, publisher = {Frank \& Timme}, address = {Berlin}, isbn = {978-3-7329-1016-8}, issn = {2193-9985}, school = {Universit{\"a}t Potsdam}, pages = {280}, year = {2024}, abstract = {Rabelais' Pentalogie um die Riesen Gargantua und Pantagruel spiegelt Aspekte des sich ver{\"a}ndernden Weltbildes ihrer Entstehungszeit. Diese Studie untersucht auf der Folie der Theorie des Simulakrum Schrift, wie K{\"o}rpermodellierungen und kartographisches imaginaire durch den Autor als Strategien der Verh{\"u}llung verborgener Botschaften eingesetzt werden. Sie zeigt an ausgew{\"a}hlten Beispielen des Quart Livre die Aufweichung der Grenzen von K{\"o}rper, Karte und Text und deren Durchdringung. Die Metaphorizit{\"a}t des Textes gibt Aufschluss {\"u}ber seine Autoreflexivit{\"a}t und bewirkt eine gleichsam ganzheitliche Lekt{\"u}reerfahrung. Schließlich avanciert die Fiktion in ihrer Trugbildhaftigkeit als grotesk-sinnlicher K{\"o}rper und polysemantische Karte zum Welterkl{\"a}rungsmodell, das jedoch erst dechiffriert werden muss.}, language = {de} } @phdthesis{Bastian2023, author = {Bastian, Martin}, title = {An emergent machine learning approach for seasonal cyclone activity forecasts}, school = {Universit{\"a}t Potsdam}, pages = {135}, year = {2023}, abstract = {Seasonal forecasts are of great interest in many areas. Knowing the amount of precipitation for the upcoming season in regions of water scarcity would facilitate a better water management. If farmers knew the weather conditions of the upcoming summer at sowing time, they could select those cereal species that are best adapted to these conditions. This would allow farmers to improve the harvest and potentially even reduce the amount of pesticides used. However, the undoubted advantages of seasonal forecasts are often opposed by their high degree of uncertainty. The great challenge of generating seasonal forecasts with lead times of several months mainly originates from the chaotic nature of the earth system. In a chaotic system, even tiny differences in the initial conditions can lead to strong deviations in the system's state in the long run. In this dissertation we propose an emergent machine learning approach for seasonal forecasting, called the AnlgModel. The AnlgModel combines the analogue method with myopic feature selection and bootstrapping. To benchmark the abilities of the AnlgModel we apply it to seasonal cyclone activity forecasts in the North Atlantic and Northwest Pacific. The AnlgModel demonstrates competitive hindcast skills with two operational forecasts and even outperforms these for long lead times. In the second chapter we comprehend the forecasting strategy of the Anlg-Model. We thereby analyse the analogue selection process for the 2017 North Atlantic and the 2018 Northwest Pacific seasonal cyclone activity. The analysis shows that those climate indices which are known to influence the seasonal cyclone activity, such as the Ni{\~n}o 3.4 SST, are correctly represented among the selected analogues. Furthermore the selected analogues reflect large-scale climate patterns that were identified by expert reports as being determinative for these particular seasons. In the third chapter we analyse the features that are used by the AnlgModel for its predictions. We therefore inspect the feature relevance (FR). The FR patterns learned by the AnlgModel show a high congruence with the predictor regions used by the operational forecasts. However, the AnlgModel also discovered new features, such as the SST anomaly in the Gulf of Guinea during November. This SST pattern exhibits a remarkably high predictive potential for the upcoming Atlantic hurricane activity. In the final chapter we investigate potential mechanisms, that link two of these regions with high feature relevance to the Atlantic hurricane activity. We mainly focus on ocean surface transport. The ocean surface flow paths are calculated using Lagrangian particle analysis. We demonstrate that the FR patterns in the region of the Canary islands do not correspond with ocean surface transport. It is instead likely that these FR patterns fingerprint a wind transport of latent heat. The second region to be studied is situated in the Gulf of Guinea. Our analysis shows that the FR patterns seen there do fingerprint ocean surface transport. However, our simulations also show that at least one other mechanism is involved in linking the Gulf of Guinea SST anomaly in November to the hurricane activity of the upcoming season. In this work the AnlgModel does not only demonstrate its outstanding forecast skills but also shows its capabilities as research tool for detecting oceanic and atmospheric mechanisms.}, language = {en} } @phdthesis{Pankaj2023, author = {Pankaj, Rishabh}, title = {Epigenetic reprogramming of seed development}, school = {Universit{\"a}t Potsdam}, pages = {182}, year = {2023}, abstract = {The development of seeds in angiosperms starts with a complex process of double fertilization, involving the fusion of the maternal egg cell and central cell with two paternal sperm cells. This gives rise to the embryo and the nourishing endosperm, which are then enclosed by the seed coat, derived from the maternal integuments. The growth of the seed coat in Arabidopsis thaliana (Arabidopsis) is actively inhibited before fertilization by epigenetic regulators known as Polycomb Group (PcG) proteins. These proteins deposit a repressive histone mark called H3K27me3, which must be removed to enable seed coat formation. In this thesis, I explored the mechanism of removal of H3K27me3 marks from the integument cells following fertilization, which allows for seed coat formation. We hypothesized that this removal should be primarily facilitated by histone demethylases from the JMJ family and potentially influenced by the plant hormones Brassinosteroids (BRs). This hypothesis was supported by the expression patterns of the JMJ protein REF6 and of BR related genes, which are specifically expressed in the integuments and in the seed coat. Moreover, mutations in both these pathways lead to developmental defects, such as reduced ovule viability and delayed seed coat growth. Our research provides evidence suggesting that BR signalling is likely involved in recruiting JMJ-type histone demethylases to target loci responsible for seed coat growth. Moreover, we have discovered an additional pathway through which BRs regulate seed coat development, independent of their influence on H3K27me3 marks. This finding emphasizes the diverse roles of BRs in coordinating seed development, extending beyond their well-known involvement in plant growth and development. Furthermore, I explored the role of another epigenetic mark, DNA methylation, in fertilization-independent (or autonomous) seed formation in Arabidopsis. For this, we utilized epigenetic Recombinant Inbred Lines (epiRILs) and thus identified an epigenetic Quantitative Trait Locus (epiQTL) on chromosome II, potentially responsible for the larger autonomous seed size observed in DNA methylation mutants. Overall, this thesis significantly enhances our comprehension of the intricate relationship between epigenetic modifications, hormonal signaling, and plant reproductive processes. It offers valuable insights into the genetic mechanisms governing both sexual and asexual seed formation, while also presenting potential avenues for the engineer of advantageous traits in agricultural crops.}, language = {en} } @phdthesis{BastosLima2023, author = {Bastos Lima, Rita}, title = {Seed coat-derived brassnosteroids non-cell autonomously regulate endosperm development}, school = {Universit{\"a}t Potsdam}, pages = {157}, year = {2023}, language = {en} } @phdthesis{Kulshreshtha2023, author = {Kulshreshtha, Ritika}, title = {Dissecting the functional of role of microtubule and cellulose microfibril patterning during flower development in Arabidopsis}, school = {Universit{\"a}t Potsdam}, pages = {215}, year = {2023}, language = {en} } @phdthesis{Ellenbeck2023, author = {Ellenbeck, Saskia}, title = {Zwischen Modellierung und Stakeholderbeteiligung - Wissensproduktion in der Energiewendeforschung}, school = {Universit{\"a}t Potsdam}, pages = {130}, year = {2023}, abstract = {Die Dekarbonisierung des Energiesystems ist Teil der international im Rahmen des Pariser Klimaabkommens beschlossenen CO2-Minderungsstrategie zur Bek{\"a}mpfung des Klimawandels. Nach den Verhandlungen und Beschl{\"u}ssen der Klimaziele stehen politische Entscheider weltweit nun vor der Frage, wie sie diese erreichen k{\"o}nnen. Dies produziert eine hohe politische Nachfrage nach Wissen um die direkten und indirekten Effekte verschiedener Instrumente und potentiellen Entwicklungspfade einer Energiewende. Dieser gesellschaftliche Bedarf an wissenschaftlichen Antworten zu L{\"o}sungsoptionen wurde im Rahmen einer Klimafolgenforschung, genauer einer Klimapolitikfolgenforschung, aufgenommen. Der relativ neue Zweig einer Energiewendeforschung hat sich weltweit entwickelt, steht dabei allerdings vor der doppelten Herausforderung: Erstens befindet sich das Objekt der Forschung nicht im luftleeren Raum, sondern innerhalb {\"o}konomischer, sozialer und politischer Zusammenh{\"a}nge, hier gesellschaftliche Einbettung genannt. Denn die Frage, wie die Energiewende erreicht werden kann, wird auch außerhalb der Wissenschaft debattiert und stellt damit ein Aushandlungsfeld unterschiedlicher Interessen und Narrative dar. Zweitens befindet sich das zu untersuchende Objekt in der Zukunft, hier unter dem Terminus des strukturellen Nicht-Wissens zusammengefasst. Diese beiden Bedingungen f{\"u}hren dazu, dass konventionelle Methoden der empirischen Sozialforschung nicht greifen und eine {\"O}ffnung und Transformation der Wissenschaft in Hinblick auf neue Methoden vonn{\"o}ten ist (Nowotny 2001, Ravetz 2006, Schneidewind 2013). In dieser Arbeit untersuche ich zwei M{\"o}glichkeiten, wie mit der Herausforderung, Wissen unter der Bedingung des strukturellen Nicht-Wissens und der gesellschaftlichen Einbettung zu produzieren, in der Energiewendeforschung umgegangen wird. Einerseits wird dies durch die Einbeziehung von Stakeholdern, also nicht-wissenschaftlicher Akteure, in den Forschungsprozess getan. Andererseits ist die Nutzung von komplexen {\"o}konometrischen Modellen zur Berechnung von Implikationen und energiewirtschaftlichen Entwicklungspfaden zu einem zentralen Mittel der Wissensgenerierung in der Energiewendeforschung avanciert. Damit wird der als Problem verstandenen strukturellen Bedingung des Nicht-Wissens insofern begegnet, als dass die Ergebnisse von Stakeholder-Involvement und von Modellierungsarbeiten zweifelsohne neues Wissen zur Verf{\"u}gung stellen. Uneinigkeit besteht jedoch darin, wor{\"u}ber dieses Wissen etwas aussagt: Sind es Interessen oder legitime Perspektiven, die Stakeholder in den Forschungsprozess einbringen und sind Modelle vereinfachte Darstellungen der Welt oder sind sie Ausdruck der Vorstellung des Modellierers?}, language = {de} } @phdthesis{Dommes2023, author = {Dommes, Bianca}, title = {»… und am Himmel standen die Sterne, aber wir sahen sie nicht«}, series = {Potsdamer J{\"u}dische Studien}, volume = {10}, journal = {Potsdamer J{\"u}dische Studien}, publisher = {be.bra wissenschaft}, address = {Berlin}, isbn = {978-3-95410-316-4}, school = {Universit{\"a}t Potsdam}, pages = {448}, year = {2023}, language = {de} } @phdthesis{SantosBruss2020, author = {Santos Bruss, Sara Morais dos}, title = {Feminist solidarities after modulation}, publisher = {punctum books}, address = {Brooklyn, NY}, isbn = {978-1-68571-146-7}, doi = {10.53288/0397.1.00}, school = {Universit{\"a}t Potsdam}, pages = {xiii, 380}, year = {2020}, abstract = {Feminist Solidarities after Modulation produces an intersectional analysis of transnational feminist movements and their contemporary digital frameworks of identity and solidarity. Engaging media theory, critical race theory, and Black feminist theory, as well as contemporary feminist movements, this book argues that digital feminist interventions map themselves onto and make use of the multiplicity and ambiguity of digital spaces to question presentist and fixed notions of the internet as a white space and technologies in general as objective or universal. Understanding these frameworks as colonial constructions of the human, identity is traced to a socio-material condition that emerges with the modernity/colonialism binary. In the colonial moment, race and gender become the reasons for, as well as the effects of, technologies of identification, and thus need to be understood as and through technologies. What Deleuze has called modulation is not a present modality of control, but is placed into a longer genealogy of imperial division, which stands in opposition to feminist, queer, and anti-racist activism that insists on non-modular solidarities across seeming difference. At its heart, Feminist Solidarities after Modulation provides an analysis of contemporary digital feminist solidarities, which not only work at revealing the material histories and affective ""leakages"" of modular governance, but also challenges them to concentrate on forms of political togetherness that exceed a reductive or essentialist understanding of identity, solidarity, and difference.}, language = {en} } @phdthesis{Hu2022, author = {Hu, Changqiong}, title = {Characterization of the role of stress - responsive NAC transcription factors ANAC055 and ATAF1}, school = {Universit{\"a}t Potsdam}, pages = {XI, 106}, year = {2022}, language = {en} } @phdthesis{Eiken2023, author = {Eiken, Jan}, title = {Das Staatenbeschwerdeverfahren der Rassendiskriminierungskonvention}, series = {Packages Social Science and Law (German Language)}, volume = {1}, journal = {Packages Social Science and Law (German Language)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-68217-3}, doi = {10.1007/978-3-662-68218-0}, school = {Universit{\"a}t Potsdam}, pages = {XIV, 359}, year = {2023}, abstract = {Obwohl sieben der neun Menschenrechtsvertr{\"a}ge auf Ebene der Vereinten Nationen die M{\"o}glichkeit eines Staatenbeschwerdeverfahrens er{\"o}ffnen, kam dieser Verfahrensart {\"u}ber Jahrzehnte hinweg keinerlei praktische Bedeutung zu. Im Fr{\"u}hjahr 2018 erreichten den CERD-Ausschuss dann jedoch gleich drei verschiedene Staatenmitteilungen. Die erstmalige Aktivierung des Verfahrens fast 50 Jahre nach Inkrafttreten des Internationalen {\"U}bereinkommens zur Beseitigung jeder Form von Rassendiskriminierung (CERD) kann dabei als eine historische Entwicklung bezeichnet werden. Vor diesem Hintergrund bietet dieses Buch erstmals eine umfassende Auseinandersetzung mit dem Staatenbeschwerdeverfahren nach Art. 11-13 CERD und den sich daraus ergebenden v{\"o}lkerrechtlichen Fragen. Unter Auswertung der j{\"u}ngsten Praxis des CERD-Ausschusses und der ad hoc Vergleichskommission wird die Funktionsweise des Verfahrens detailliert dargestellt, wobei immer wieder Parallelen zu den Mechanismen anderer Vertragsregime gezogen werden. Auf diese Weise soll die Arbeit auch zu dem Verst{\"a}ndnis vergleichbarer Staatenbeschwerdeverfahren anderer Menschenrechtsvertr{\"a}ge beitragen und zugleich die Bedeutung des Ph{\"a}nomens zwischenstaatlicher Streitbeilegung in Menschenrechtsfragen st{\"a}rker in den Vordergrund r{\"u}cken.}, language = {de} } @phdthesis{Machani2023, author = {Machani, Fridah Gechemba}, title = {Functional analysis of ATAF1 and ANAC032 NAC transcription factors in response to nitrogen Supply in Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {126}, year = {2023}, language = {en} } @phdthesis{RomeroPrada2023, author = {Romero Prada, Lorena Margarita}, title = {Crop improvement towards oxidative stress}, school = {Universit{\"a}t Potsdam}, pages = {155}, year = {2023}, language = {en} } @phdthesis{Sharma2023, author = {Sharma, Anjali}, title = {Optical manipulation of multi-responsive microgels}, school = {Universit{\"a}t Potsdam}, pages = {207}, year = {2023}, abstract = {This dissertation focuses on the understanding of the optical manipulation of microgels dispersed in aqueous solution of azobenzene containing surfactant. The work consists of three parts where each part is a systematic investigation of the (1) photo-isomerization kinetics of the surfactant in complex with the microgel polymer matrix, (2) light driven diffusiosmosis (LDDO) in microgels and (3) photo-responsivity of microgel on complexation with spiropyran. The first part comprises three publications where the first one [P1] investigates the photo-isomerization kinetics and corresponding isomer composition at a photo-stationary state of the photo-sensitive surfactant conjugated with charged polymers or micro sized polymer networks to understand the structural response of such photo-sensitive complexes. We report that the photo-isomerization of the azobenzene-containing cationic surfactant is slower in a polymer complex compared to being purely dissolved in an aqueous solution. The surfactant aggregates near the polyelectrolyte chains at concentrations much lower than the bulk critical micelle concentration. This, along with the inhibition of the photo-isomerization kinetics due to steric hindrance within the densely packed aggregates, pushes the isomer-ratio to a higher trans-isomer concentration for all irradiation wavelengths. The second publication [P2] combines experimental results and non-adiabatic dynamic simulations for the same surfactant molecules embedded in the micelles with absorption spectroscopy measurements of micellar solutions to uncover the reasons responsible for the slowdown in photo induced trans → cis azobenzene isomerization at concentrations higher than the critical micelle concentration (CMC). The simulations reveal a decrease of isomerization quantum yields for molecules inside the micelles and observes a reduction of extinction coefficients upon micellization. These findings explain the deceleration of the trans → cis switching in micelles of the azobenzene-containing surfactants. Finally, the third publication [P3] focusses on the kinetics of adsorption and desorption of the same surfactant within anionic microgels in the dark and under continuous irradiation. Experimental data demonstrate, that microgels can serve as a selective absorber of the trans isomers. The interaction of the isomers with the gel matrix induces a remotely controllable collapse or swelling on appropriate irradiation wavelengths. Measuring the kinetics of the microgel size response and knowing the exact isomer composition under light exposure, we calculate the adsorption rate of the trans-isomers. The second part comprises two publications. The first publication [P4] reports on the phenomenon of light-driven diffusioosmotic (DO) long-range attractive and repulsive interactions between micro-sized objects, whose range extends several times the size of microparticles and can be adjusted to point towards or away from the particle by varying irradiation parameters such as intensity or wavelength of light. The phenomenon is fueled by the aforementioned photosensitive surfactant. The complex interaction of dynamic exchange of isomers and photo-isomerization rate yields to relative concentrations gradients of the isomers in the vicinity of micro-sized object inducing a local diffusioosmotic (DO) flow thereby making a surface act as a micropump. The second publication [P5] exclusively aims the visualization and investigation of the DO flows generated from microgels by using small tracer particles. Similar to micro sized objects, the flow is able to push adjacent tracers over distances several times larger than microgel size. Here we report that the direction and the strength of the l-LDDO depends on the intensity, irradiation wavelength and the amount of surfactant adsorbed by the microgel. For example, the flow pattern around a microgel is directed radially outward and can be maintained quasi-indefinitely under exposure at 455 nm when the trans:cis ratio is 2:1, whereas irradiation at 365 nm, generates a radially transient flow pattern, which inverts at lower intensities. Lastly, the third part consists of one publication [P6] which, unlike the previous works, reports on the study of the kinetics of photo- and thermo-switching of a new surfactant namely, spiropyran, upon exposure with light of different wavelengths and its interaction with p(NIPAM-AA) microgels. The surfactant being an amphiphile, switches between its ring closed spiropyran (SP) form and ring open merocyanine (MC) form which results in a change in the hydrophilic-hydrophobic balance of the surfactant as MC being a zwitterionic form along with the charged head group, generates three charges on the molecule. Therefore, the MC form of the surfactant is more hydrophilic than in the case of the neutral SP state. Here, we investigate the initial shrinkage of the gel particles via charge compensation on first exposure to SP molecules which results from the complex formation of the molecules with the gel matrix, triggering them to become photo responsive. The size and VPTT of the microgels during irradiation is shown to be a combination of heating up of the solution during light absorption by the surfactant (more pronounced in the case of UV irradiation) and the change in the hydrophobicity of the surfactant.}, language = {en} } @phdthesis{Agarwal2023, author = {Agarwal, Pallavi}, title = {Functional characterization of ROS-responsive genes, ANAC085 and ATR7, in Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {XVII, 169}, year = {2023}, language = {en} } @phdthesis{Peng2023, author = {Peng, Maolin}, title = {The role of prion-like domains in plant temperatur sensing}, school = {Universit{\"a}t Potsdam}, pages = {XVI, 121}, year = {2023}, language = {en} } @phdthesis{Stephan2023, author = {Stephan, Mareike Sophia}, title = {A bacterial mimetic system to study bacterial inactivation and infection}, school = {Universit{\"a}t Potsdam}, pages = {150}, year = {2023}, abstract = {The emerging threat of antibiotic-resistant bacteria has become a global challenge in the last decades, leading to a rising demand for alternative treatments for bacterial infections. One approach is to target the bacterial cell envelope, making understanding its biophysical properties crucial. Specifically, bacteriophages use the bacterial envelope as an entry point to initiate infection, and they are considered important building blocks of new antibiotic strategies against drug-resistant bacteria.. Depending on the structure of the cell wall, bacteria are classified as Gram-negative and Gram-positive. Gram-negative bacteria are equipped with a complex cell envelope composed of two lipid membranes enclosing a rigid peptidoglycan layer. The synthesis machinery of the Gram-negative cell envelope is the target of antimicrobial agents, including new physical sanitizing procedures addressing the outer membrane (OM). It is therefore very important to study the biophysical properties of the Gram-negative bacterial cell envelope. The high complexity of the Gram-negative OM sets the demand for a model system in which the contribution of individual components can be evaluated separately. In this respect, giant unilamellar vesicles (GUVs) are promising membrane systems to study membrane properties while controlling parameters such as membrane composition and surrounding medium conditions. The aim of this work was to develop methods and approaches for the preparation and characterization of a GUV-based membrane model that mimics the OM of the Gram-negative cell envelope. A major component of the OM is the lipopolysaccharide (LPS) on the outside of the OM heterobilayer. The vesicle model was designed to contain LPS in the outer leaflet and lipids in the inner leaflet. Furthermore, the interaction of the prepared LPS-GUVs with bacteriophages was tested. LPS containing GUVs were prepared by adapting the inverted emulsion technique to meet the challenging properties of LPS, namely their high self-aggregation rate in aqueous solutions. Notably, an additional emulsification step together with the adaption of solution conditions was employed to asymmetrically incorporate LPS containing long polysaccharide chains into the artificial membranes. GUV membrane asymmetry was verified with a fluorescence quenching assay. Since the necessary precautions for handling the quenching agent sodium dithionite are often underestimated and poorly described, important parameters were tested and identified to obtain a stable and reproducible assay. In the context of varied LPS incorporation, a microscopy-based technique was introduced to determine the LPS content on individual GUVs and to directly compare vesicle properties and LPS coverage. Diffusion coefficient measurements in the obtained GUVs showed that increasing LPS concentrations in the membranes resulted in decreased diffusivity. Employing LPS-GUVs we could demonstrate that a Salmonella bacteriophage bound with high specificity to its LPS receptor when presented at the GUV surface, and that the number of bound bacteriophages scaled with the amount of presented LPS receptor. In addition to binding, the bacteriophages were able to eject their DNA into the vesicle lumen. LPS-GUVs thus provide a starting platform for bottom-up approaches for the generation of more complex membranes, in which the effects of individual components on the membrane properties and the interaction with antimicrobial agents such as bacteriophages could be explored.}, language = {en} } @phdthesis{Li2023, author = {Li, Xiaoping}, title = {Regulation of starch granule number and morphology in arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {116}, year = {2023}, language = {en} } @phdthesis{Koelman2023, author = {Koelman, Liselot A.}, title = {The role of diet in immune health and ageing}, school = {Universit{\"a}t Potsdam}, year = {2023}, language = {en} } @phdthesis{RuoffnerUnterrainer2023, author = {Ruoffner-Unterrainer, Simone}, title = {Zwischen Verein, Korporation und Gesinnungsgemeinschaft}, series = {Abhandlungen zum Studenten- und Hochschulwesen}, volume = {22}, journal = {Abhandlungen zum Studenten- und Hochschulwesen}, publisher = {B{\"o}hlau}, address = {Wien ; K{\"o}ln}, isbn = {978-3-412-52837-9}, school = {Universit{\"a}t Potsdam}, pages = {455}, year = {2023}, language = {de} } @phdthesis{Klein2023, author = {Klein, Jonas}, title = {Der Prophet des Staatsgedankens}, series = {Schriftenreihe der Historischen Kommission bei der Bayerischen Akademie der Wissenschaften}, volume = {111}, journal = {Schriftenreihe der Historischen Kommission bei der Bayerischen Akademie der Wissenschaften}, publisher = {Vandenhoeck \& Ruprecht}, address = {G{\"o}ttingen}, isbn = {978-3-525-30238-5}, issn = {0568-4323}, pages = {471}, year = {2023}, abstract = {Kaum eine Studie zum Deutschen Kaiserreich kommt ohne einen Verweis auf die »Preußischen Jahrb{\"u}cher« als einflussreicher Stimme der Zeit aus, deren Herausgeber Hans Delbr{\"u}ck keine Kontroverse scheute. Jonas Kleins systematische Beziehungsgeschichte untersucht, woher das Vertrauen resultierte, das Hans Delbr{\"u}ck als politischer Intellektueller partei{\"u}bergreifend genoss. Indem die wichtigsten innen- und außenpolitischen Krisenherde des Kaiserreichs in den Blick genommen werden, kristallisieren sich die politischen Grundlinien heraus, auf die Delbr{\"u}ck die »Preußischen Jahrb{\"u}cher« verpflichtete: f{\"u}r einen starken Staat, kulturellen Liberalismus, progressive Sozialpolitik und nationale Integration. Sein unerm{\"u}dlicher, keineswegs solit{\"a}rer Kampf f{\"u}r einen »aufgekl{\"a}rten Konservatismus« zeugt von alternativen Entwicklungsoptionen des Hohenzollernstaates.}, language = {de} } @phdthesis{Batti2023, author = {Batti, Anil Dominic}, title = {Schopenhauer's doctrine of salvation in relation to his critique of religion and philosophical teachings}, publisher = {Logos}, address = {Berlin}, isbn = {978-3-83255-735-5}, school = {Universit{\"a}t Potsdam}, pages = {319}, year = {2023}, abstract = {Arthur Schopenhauer (1788-1860) was perhaps the last polymath among the great Germanic philosophers. Switching with ease and elegance between epistemic positions and fields as diverse as idealism and empiricism, fideism and rationalism, realism and nominalism, art and religion, jurisprudence and politics, psychology and occultism, Schopenhauer erected an imposing edifice bearing testimony to his universal learning. This study is an investigation into the very conclusion of Schopenhauer's philosophy and endeavours to answer the following question: did Schopenhauer's doctrine of salvation issue forth organically from his intellectual output or was it annexed to his philosophy as a result of his critical engagement with religion? The labyrinthine paths through which Schopenhauer arrives at the soteriological culmination of his philosophy are subjected to critical assessment; the picture that emerges is of a philosopher who seemed convinced that he had solved some of the most pressing cosmic riddles to have tormented mankind through the ages.}, language = {en} } @phdthesis{Khawaja2023, author = {Khawaja, Muhammad Asim}, title = {Improving earthquake forecast modeling and testing using the multi-resolution grids}, school = {Universit{\"a}t Potsdam}, pages = {107}, year = {2023}, language = {en} } @phdthesis{Sajedi2023, author = {Sajedi, Maryam}, title = {Investigation of metal-halide-perovskites by state-of-the-art synchrotron-radiation methods}, school = {Universit{\"a}t Potsdam}, pages = {xviii, 149}, year = {2023}, abstract = {My thesis chiefly aims to shed light on the favourable properties of LHP semiconductors from the point of view of their electronic structure. Currently, various hypotheses are circulating to explain the exceptionally favourable transport properties of LHPs. Seeking an explanation for the low non-radiative recombination rates and long carrier lifetimes is particularly interesting to the halide perovskites research community. The first part of this work investigates the two main hypotheses that are believed to play a significant role: the existence of a giant Rashba effect and large polarons. The experimental method of ARPES is mainly applied to verify their credibility. The first hypothesis presumes that a giant Rashba effect restricts the recombination losses of the charge carriers by making the band gap slightly indirect. The Rashba effect is based on a strong SOC that could appear in LHPs thanks to incorporating the heavy element Pb in their structure. Earlier experimental work had pointed out this effect at the VBM of a hybrid LHP as a viable explanation for the long lifetimes of the charge carriers. My systematic ARPES studies on hybrid MAPbBr3 and spin-resolved ARPES studies on the inorganic CsPbBr3 disprove the presence of any Rashba effect in the VBM of the reported order of magnitude. Therefore, neither the spin texture nor an indirect band gap character at the VBM in the bulk or at the surface can explain the high efficiency of LHP. In case of existence, this effect is in terms of the Rashba parameter at least a factor of a hundred smaller than previously assumed. The second hypothesis proposes large polaron formation in the electronic structure of LHPs and attributes it to their high defect tolerance and low non-radiative recombination rate. Because the perovskite structure consists of negative and positive ions, polarons of this kind can be expected due to the Coulomb interaction between carriers and the polar lattice at intermediate electron-phonon coupling strength. Their existence is proposed to screen the carriers and defects to avoid recombination and trapping, thus leading to long carrier lifetimes. ARPES results by one group supported this assumption, reporting a 50\% effective mass enhancement over the theoretical effective mass for CsPbBr3 in the orthorhombic structure. The current thesis examines this hypothesis experimentally by photon-energy-dependent ARPES spectra and theoretically by GW band calculations of CsPbBr3 perovskites. The investigation is based on the fact that a polaron contribution in charge transport can become evident by an increase of the effective mass as measured by ARPES over the calculated one without polaron effects. However, my experiments on crystalline CsPbBr3 did not imply a larger effective mass for which one could postulate large polarons. In fact, the effective masses determined from ARPES agree with that of theoretical predictions. The second part of my thesis thoroughly investigates the possibility of spontaneously magnetizing LHPs by introducing Mn2+ ions. Mn doping was reported to cause ferromagnetism in one of the most common LHPs, MAPbI3, mediated by super-exchange. The current work investigates the magnetic properties of a wide concentration range of Mn-doped MAPbI3 and triple-cation films by XAS, XMCD, and SQUID measurements. Based on the XAS line shape and a sum-rule analysis of the XMCD spectra, a pure Mn2+ configuration has been confirmed. Negative Curie temperatures are extracted from fitting the magnetization with a Curie-Weiss law. However, a remanent magnetization, which would be an indication of the absence of ferromagnetism down to 2K. As far as the double exchange is concerned, the element-specific XAS excludes a sufficient amount of Mn3+ as a prerequisite for this mechanism. All the findings show no evidence of significant double exchange or ferromagnetism in Mn-doped LHPs. The magnetic behavior is paramagnetic rather than ferromagnetic. In the dissertation's last chapter, orthorhombic features of CsPbBr3 are revealed by ARPES, including an extra VBM at the Γ-point. The VBM of CsPbBr3 shows a temperature-dependent splitting, which decreases by 190 meV between 38K and 300K and tracks a shift of a saddle point at the cubic M-point. It is possible to reproduce the energy shift using an atomic model with a larger unit cell for room temperature, allowing local inversion symmetry breaking. This indicates the importance of electric dipoles for the inorganic LHPs, which may contribute to their high efficiency by breaking inversion symmetry and a Berry-phase effect.}, language = {en} } @phdthesis{Pietrek2023, author = {Pietrek, Anou F.}, title = {Basic psychological needs and depression in the context of health and exercise}, school = {Universit{\"a}t Potsdam}, year = {2023}, abstract = {Depressive Erkrankungen gehen mit verminderter Lebenszufriedenheit und reduzierter Arbeitsf{\"a}higkeit einher. Die Wartezeit f{\"u}r eine Psychotherapie betr{\"a}gt in Deutschland derzeit zwischen drei und sechs Monaten. Demnach besteht Bedarf an alternativen, gleichwertigen evidenzbasierten Behandlungsm{\"o}glichkeiten, die den Betroffenen niedrigschwellig zug{\"a}nglich gemacht werden. Eine Vielzahl an empirischen Studien belegt die Wirksamkeit von Sport bei leichten und mittelschweren Depressionen. Zur weiterf{\"u}hrenden Konzeption und Qualit{\"a}tssicherung von Sport als Behandlungsoption ist es notwendig die konkreten Wirkmechanismen zu verstehen. Neben physiologischen spielen auch psychologische Faktoren eine Rolle im Wirkungsgeschehen. Als Metatheorie menschlichen Erlebens und Verhaltens bietet die Selbstbestimmungstheorie (engl.: Self-Determination Theory; SDT) einen n{\"u}tzlichen Bezugsrahmen zum Verst{\"a}ndnis psychologischer Wirkmechanismen mit konkreten Ableitungen f{\"u}r die Behandlungspraktik. Die konzeptionelle Erweiterung der SDT um die Frustration psychologischer Grundbed{\"u}rfnisse erweist sich neben der Bed{\"u}rfnisbefriedigung zunehmend als hilfreich bei der Untersuchung von psychischen Erkrankungen. Der erste Teil dieser Dissertation besteht aus zwei Publikationen, die relevante Messinstrumente in dem genannten Kontext validieren. Der erste Fragebogen misst das Ausmaß an allgemein erlebter Befriedigung und Frustration der psychologischen Grundbed{\"u}rfnisse nach Autonomie, Kompetenz und sozialer Eingebundenheit. Der zweite Fragebogen erhebt die erlebte Bed{\"u}rfnisbefriedigung durch die anleitende Person (hier: Sporttherapeut*in). Der zweite Teil der Dissertation umfasst zwei Publikationen, welche die Befriedigung und Frustration der psychologischen Grundbed{\"u}rfnisse bei depressiven Symptomen untersuchen und einordnen. Es werden die Unterschiede im Ausmaß an Bed{\"u}rfnisbefriedigung und Bed{\"u}rfnisfrustration zwischen einer Stichprobe mit Depression mit einer Stichprobe ohne depressive Symptome untersucht. Der Zusammenhang zwischen Bed{\"u}rfnisfrustration und depressiven Symptomen wird im Kontext etablierter pathologischer Prozesse (Emotionsdysregulation, Rumination) eingeordnet. Die Hauptergebnisse dieser Arbeiten zeigen, dass die SDT durch die Erweiterung der Basic Psychological Needs Theory um die Dimension der Bed{\"u}rfnisfrustration ein nun breiteres Spektrum auf dem Gesundheit-Krankheit-Kontinuum abbildet. Dabei fokussiert die SDT auf die psychologische Wirkung von sozialen Umwelten. Neben der Nichterf{\"u}llung der psychologischen Grundbed{\"u}rfnisse ist es vor allem die Bed{\"u}rfnisfrustration, die einen allgemeinen Vulnerabilit{\"a}tsfaktor f{\"u}r das Vorkommen psychologischer Erkrankungen darstellt. Zudem weist die unausgewogene Befriedigung der psychologischen Grundbed{\"u}rfnisse m{\"o}glicherweise auf ein konflikthaftes Erleben zwischen den Bed{\"u}rfnissen hin. F{\"u}r die Behandlungspraktik abzuleiten ist, dass eine autonomieunterst{\"u}tzende Atmosph{\"a}re, die die ausgewogene Befriedigung aller drei Bed{\"u}rfnisse erm{\"o}glicht, zentral f{\"u}r den Behandlungserfolg ist.}, language = {en} } @phdthesis{Baryzewska2023, author = {Baryzewska, Agata W.}, title = {Reconfigurable Janus emulsions as signal transducers for biosensing applications}, school = {Universit{\"a}t Potsdam}, pages = {133}, year = {2023}, language = {en} } @phdthesis{Vassilevski2023, author = {Vassilevski, Ekaterina}, title = {Hegels Phantasie}, series = {Edition Medienwissenschaft}, volume = {107}, journal = {Edition Medienwissenschaft}, publisher = {Transcript}, address = {Bielefeld}, isbn = {978-3-8394-6959-0}, school = {Universit{\"a}t Potsdam}, pages = {175}, year = {2023}, abstract = {Als »Zwischenreich«, »Drittes« oder »Mitte« bezeichnet, kommt der Imagination seit ihren Anf{\"a}ngen in der Antike die Rolle eines Mediums zu. Gleichzeitig bleibt ihr medialer Aspekt durchgehend ambivalent und prek{\"a}r. Es ist Georg Wilhelm Friedrich Hegel, der die Imagination nicht mehr als subjektives Verm{\"o}gen versteht, sondern als Kraft der »Ent{\"a}ußerung« und sie somit medial denkt. In einer bislang wenig beachteten Passage aus Hegels dritter Enzyklop{\"a}die von 1830 legt Ekaterina Vassilevski nicht nur die implizite Medialit{\"a}t der Imagination frei, sondern auch den in Hegels Denken verborgenen Begriff des Medialen.}, language = {de} } @phdthesis{Lian2023, author = {Lian, Tingting}, title = {Efficient activation of peroxymonosulfate by carbon-based catalysts for water purification}, school = {Universit{\"a}t Potsdam}, pages = {167}, year = {2023}, abstract = {The increasing global population has led to a growing demand for cost-effective and eco-friendly methods of water purification. This demand has reached a peak due to the increasing presence of impurities and pollutants in water and a growing awareness of waterborne diseases. Advanced oxidation processes (AOPs) are effective methods to address these challenges, due to the generation of highly reactive radicals, such as sulfate radical (SO4•-), hydroxyl radical (•OH), and/or superoxide radical (•O2-) in oxidation reactions. Relative to conventional hydrogen peroxide (H2O2)-based AOPs for wastewater treatment, the persulfate-related AOPs are receiving increasing attention over the past decades, due to their stronger oxidizing capability and a wider pH working window. Further deployment of the seemingly plausible technology as an alternative for the well-established one in industry, however, necessitates a careful evaluation of compounding factors, such as water matrix effects, toxicological consequences, costs, and engineering challenges, etc. To this end, rational design of efficient and environmentally friendly catalysts constitutes an indispensable pathway to advance persulfate activation efficacy and to elucidate the mechanisms in AOPs, the combined endeavors are expected to provide insightful understanding and guidelines for future studies in wastewater treatment. A dozens of transition metal-based catalysts have been developed for persulfate-related AOPs, while the undesirable metal leaching and poor stability in acidic conditions have been identified as major obstacles. Comparatively, the carbonaceous materials are emerging as alternative candidates, which are characterized by metal-free nature, wide availability, and exceptional resistance to acid and alkali, as well as tunable physicochemical and electronic properties, the combined merits make them an attractive option to overcome the aforementioned limitations in metal-based catalytic systems. This dissertation aims at developing novel carbonaceous materials to boost the activity in peroxymonosulfate (PMS) activation processes. Functionalized carbon materials with metal particles or heteroatoms were constructed and further evaluated in terms of their ability to activate PMS for AOPs. The main contents of this thesis are summarized as follows: (1) Iron oxide-loaded biochar: improving stability and alleviating metal leakage Metal leaching constitutes one of the main drawbacks in using transition metals as PMS activators, which is accompanied by the generation of metal-containing sludge, potentially leading to secondary pollution. Meanwhile, the metal nanoparticles are prone to aggregate, causing rapid decay of catalytic performance. The use of carbons as supports for transition metals could mitigate these deficiencies, because the interaction between metals and carbons could in turn disperse and stabilize metal nanoparticles, thus suppressing the metal leaching. In this work, the environmentally benign lignin with its abundant phenolic groups, which is well known to serve as carbon source with high yields and flexibility, was utilized to load Fe ions. The facile low-temperature pre-treatment pyrolytic strategy was employed to construct a green catalyst with iron oxides embedded in Kraft-lignin-derived biochar (termed as γ-Fe2O3@KC). The γ-Fe2O3@KC was capable of activating PMS to generate stable non-radical species (1O2 and Fe (V)=O) and to enhance electron transfer efficiency. A surface-bound reactive complex (catalyst-PMS*) was identified by electrochemical characterizations and discussed with primary surface-bound radical pairs to explain the contradictions between quenching and EPR detection results. The system also showed encouraging reusability for at least 5 times and high stability at pH 3-9. The low concentration of iron in γ-Fe2O3@KC/PMS system implied that the carbon scaffold of biochar substantially alleviated metal leakage. (2) MOF-derived nanocarbon: new carbon crystals Traditional carbon materials are of rather moderate performance in activation PMS, due to the poor electron transfer capacity within the amorphous structure and limited active sites for PMS adsorption. Herein, we established crystalline nanocarbon materials via a simple NaCl-templated strategy using the monoclinic zeolitic imidazolate framework-8 (ZIF-8) sealed with NaCl crystals as the precursors. Specifically, NaCl captured dual advantages in serving as structure-directing agent during hydrolysis and protective salt reactor to facilitate phase transformation during carbonization. The structure-directing agent NaCl provided a protective and confined space for the evolution of MOF upon carbonization, which led to high doping amounts of nitrogen (N) and oxygen elements (O) in carbon framework (N: 14.16 wt\%, O: 9.6 wt\%) after calcination at a high temperature of 950 oC. We found that N-O co-doping can activate the chemically inert carbon network and the nearby sp2-hybridized carbon atoms served as active sites for adsorption and activation. Besides, the highly crystallized structure with well-established carbon channels around activated carbon atoms could significantly accelerate electron transfer process after initial adsorption of PMS. As such, this crystalline nanocarbon exhibited excellent catalytic kinetics for various pollutants. (3) MOF-derived 2D carbon layers: enhanced mass/electron transfer The two-dimensional (2D) configuration of carbon-based nanosheets with inherent nanochannels and abundant active sites residing on the layer edges or in between the layers, allowed the accessible interaction and close contact between the substrates and reactants, as well as the dramatically improved electron- and mass-transfer kinetics. In this regard, we developed dual-templating strategy to afford 2D assembly of the crystalline carbons, which found efficiency in reinforcing the interactions between the catalyst surface and foreign pollutants. Specifically, we found that the ice crystals and NaCl promoted the evolution of MOF in a 2D fashion during the freezing casting stage, while the later further allowed the formation of a graphitic surface at high calcination temperature, by virtue of the templating effect of molten salt. Due to the highly retained co-doping amounts, N and O heteroatoms created abundant active sites for PMS activation, the 2D configuration of carbon-based nanosheets enable efficient interaction of PMS and pollutants on the surface, which further boosted the kinetics of degradation.}, language = {en} } @phdthesis{Konopka2023, author = {Konopka, Torsten}, title = {Deutsche Blauhelme in Afrika}, series = {Bundeswehr im Einsatz}, volume = {5}, journal = {Bundeswehr im Einsatz}, publisher = {Vandenhoeck \& Ruprecht}, address = {G{\"o}ttingen}, isbn = {978-3-525-30239-2}, school = {Universit{\"a}t Potsdam}, pages = {780}, year = {2023}, abstract = {Warum trat die Bundesregierung ab Ende der 1980er Jahre weltweit als sicherheitspolitischer Akteur in Erscheinung? Warum engagierte sie sich in multinationalen Missionen der Vereinten Nationen etwa in Somalia, Namibia und Ruanda mit Soldaten oder Polizisten - und in anderen Missionen in Afrika im gleichen Zeitraum nicht? Gest{\"u}tzt auf ministerielle Archivquellen untersucht Torsten Konopka die Prozesse der nationalen Entscheidungsfindung, die zu einer Beteiligung oder Nichtbeteiligung an VN-Missionen in Afrika f{\"u}hrten. Das Buch leistet einen politik- sowie milit{\"a}rgeschichtlichen Beitrag zur Genese der fr{\"u}hen Auslandsverwendungen der Bundeswehr.}, language = {de} } @phdthesis{LopesFernando2023, author = {Lopes Fernando, Raquel Sofia}, title = {The impact of aging on proteolytic systems, transcriptome and metabolome of slow and fast muscle fiber types}, doi = {10.25932/publishup-60579}, school = {Universit{\"a}t Potsdam}, pages = {XI, 125}, year = {2023}, abstract = {Aging is a complex process characterized by several factors, including loss of genetic and epigenetic information, accumulation of chronic oxidative stress, protein damage and aggregates and it is becoming an emergent drug target. Therefore, it is the utmost importance to study aging and agerelated diseases, to provide treatments to develop a healthy aging process. Skeletal muscle is one of the earliest tissues affected by age-related changes with progressive loss of muscle mass and function from 30 years old, effect known as sarcopenia. Several studies have shown the accumulation of protein aggregates in different animal models, as well as in humans, suggesting impaired proteostasis, a hallmark of aging, especially regarding degradation systems. Thus, different publications have explored the role of the main proteolytic systems in skeletal muscle from rodents and humans, like ubiquitin proteasomal system (UPS) and autophagy lysosomal system (ALS), however with contradictory results. Yet, most of the published studies are performed in muscles that comprise more than one fiber type, that means, muscles composed by slow and fast fibers. These fiber types, exhibit different metabolism and contraction speed; the slow fibers or type I display an oxidative metabolism, while fast fibers function towards a glycolytic metabolism ranging from fast oxidative to fast glycolytic fibers. To this extent, the aim of this thesis sought to understand on how aging impacts both fiber types not only regarding proteostasis but also at a metabolome and transcriptome network levels. Therefore, the first part of this thesis, presents the differences between slow oxidative (from Soleus muscle) and fast glycolytic fibers (Extensor digitorum longus, EDL) in terms of degradation systems and how they cope with oxidative stress during aging, while the second part explores the differences between young and old EDL muscle transcriptome and metabolome, unraveling molecular features. More specifically, the results from the present work show that slow oxidative muscle performs better at maintaining the function of UPS and ALS during aging than EDL muscle, which is clearly affected, accounting for the decline in the catalytic activity rates and accumulation of autophagy-related proteins. Strinkingly, transcriptome and metabolome analyses reveal that fast glycolytic muscle evidences significant downregulation of mitochondrial related processes and damaged mitochondria morphology during aging, despite of having a lower oxidative metabolism compared to oxidative fibers. Moreover, predictive analyses reveal a negative association between aged EDL gene signature and lifespan extending interventions such as caloric restriction (CR). Although, CR intervention does not alter the levels of mitochondrial markers in aged EDL muscle, it can reverse the higher mRNA levels of muscle damage markers. Together, the results from this thesis give new insights about how different metabolic muscle fibers cope with age-related changes and why fast glycolytic fibers are more susceptible to aging than slow oxidative fibers.}, language = {en} } @phdthesis{Palm2023, author = {Palm, Stefanie}, title = {F{\"o}rdern und Zensieren}, series = {Ver{\"o}ffentlichung zur Geschichte der deutschen Innenministerien nach 1945}, volume = {7}, journal = {Ver{\"o}ffentlichung zur Geschichte der deutschen Innenministerien nach 1945}, publisher = {Wallstein}, address = {G{\"o}ttingen}, isbn = {978-3-8353-8512-2}, school = {Universit{\"a}t Potsdam}, pages = {592}, year = {2023}, language = {de} } @phdthesis{Cho2023, author = {Cho, Danbi}, title = {Relativierung des Bestandsschutzes durch Einfl{\"u}sse des europ{\"a}ischen Umweltrechts?}, series = {Schriften zum Umweltrecht}, volume = {201}, journal = {Schriften zum Umweltrecht}, publisher = {Duncker \& Humblot}, address = {Berlin}, isbn = {978-3-428-18871-0}, doi = {10.3790/978-3-428-58871-8}, school = {Universit{\"a}t Potsdam}, pages = {397}, year = {2023}, abstract = {»European Environmental Law and its Influence on Grandfathering - a Limiting Factor?«: How to deal with conflicts that arise between legally permitted activities and nature despite prior comprehensive environmental assessments? The author examines this question regarding EU species, habitat protection and environmental damage law. The material EU environmental law requirements for the use of permits are outlined, as well as the administrative instruments for their enforcement. A differentiation is made between permits under the Federal Immission Control Act and plan approvals.}, language = {de} } @phdthesis{Berndt2023, author = {Berndt, Sebastian}, title = {Das Verwenden von Kennzeichen verfassungswidriger Organisationen in Computerspielen im Spiegel des \S 86a Abs. 1 Nr. 1 StGB und des Jugendmedienschutzes}, series = {Schriften zum Strafrecht}, volume = {414}, journal = {Schriften zum Strafrecht}, publisher = {Duncker \& Humblot}, address = {Berlin}, isbn = {978-3-428-58834-3}, school = {Universit{\"a}t Potsdam}, pages = {411}, year = {2023}, language = {de} } @phdthesis{Valade2023, author = {Valade, Aurelien Niels Valentin}, title = {Unveiling the Local Universe}, school = {Universit{\"a}t Potsdam}, pages = {X, 102}, year = {2023}, language = {en} } @phdthesis{Ludwig2022, author = {Ludwig, Julia}, title = {Foreigners by Birth - Croatian by Blood}, series = {Krieg und Konflikt}, journal = {Krieg und Konflikt}, publisher = {Campus}, address = {Frankfurt am Main}, isbn = {978-3-59345-508-2}, pages = {463}, year = {2022}, abstract = {Was bewegt Menschen dazu, freiwillig in einem Krieg zu k{\"a}mpfen, obwohl ihr Heimatland nicht involviert ist? Warum riskieren sie in Konflikten weltweit ihr Leben f{\"u}r eine fremde Sache? Bedeutet das Fehlen institutioneller Strukturen, die den Akteuren klare Regeln und Verhaltensweisen vorgeben w{\"u}rden, immer eine Eskalation von Gewalt? Diese Studie hilft, das Ph{\"a}nomen freiwilliger Kombattanten zu verstehen. Am Fallbeispiel internationaler Kriegsfreiwilliger, die in den Jugoslawienkriegen der 1990er Jahre auf Seiten Kroatiens k{\"a}mpften, macht Julia Ludwig zudem den Mehrwert einer Analyse kultureller Faktoren in der Gewaltforschung deutlich.}, language = {de} } @phdthesis{Sarlet2023, author = {Sarlet, Adrien}, title = {Tuning the viscoelasticity of Escherichia coli biofilms}, school = {Universit{\"a}t Potsdam}, pages = {143}, year = {2023}, abstract = {Biofilms are heterogeneous structures made of microorganisms embedded in a self-secreted extracellular matrix. Recently, biofilms have been studied as sustainable living materials with a focus on the tuning of their mechanical properties. One way of doing so is to use metal ions. In particular biofilms have been shown to stiffen in presence of some metal cations and to soften in presence of others. However, the specificity and the determinants of those interactions vary between species. While Escherichia coli is a widely studied model organism, little is known concerning the response of its biofilms to metal ions. In this work, we aimed at tuning the mechanics of E. coli biofilms by acting on the interplay between matrix composition and metal cations. To do so, we worked with E. coli strains producing a matrix composed of curli amyloid fibres or phosphoethanolamine-cellulose (pEtN-cellulose) fibres or both. The viscoelastic behaviour of the resulting biofilms was investigated with rheology after incubation with one of the following metal ion solutions: FeCl3, AlCl3, ZnCl2 and CaCl2 or ultrapure water. We observed that the strain producing both fibres stiffen by a factor of two when exposed to the trivalent metal cations Al(III) and Fe(III) while no such response is observed for the bivalent cations Zn(II) and Ca(II). Strains producing only one matrix component did not show any stiffening in response to either cation, but even a small softening. In order to investigate further the contribution of each matrix component to the mechanical properties, we introduced additional bacterial strains producing curli fibres in combination with non-modified cellulose, non-modified cellulose only or neither component. We measured biofilms produced by those different strains with rheology and without any solution. Since rheology does not preserve the architecture of the matrix, we compared those results to the mechanical properties of biofilms probed with the non-destructive microindentation. The microindentation results showed that biofilm stiffness is mainly determined by the presence of curli amyloid fibres in the matrix. However, this clear distinction between biofilm matrices containing or not containing curli is absent from the rheology results, i.e. following partial destruction of the matrix architecture. In addition, rheology also indicated a negative impact of curli on biofilm yield stress and flow stress. This suggests that curli fibres are more brittle and therefore more affected by the mechanical treatments. Finally, to examine the molecular interactions between the biofilms and the metal cations, we used Attenuated total reflectance - Fourier transform infrared spectroscopy (ATR-FTIR) to study the three E.coli strains producing a matrix composed of curli amyloid fibres, pEtN-cellulose fibres or both. We measured biofilms produced by those strains in presence of each of the aforementioned metal cation solutions or ultrapure water. We showed that the three strains cannot be distinguished based on their FTIR spectra and that metal cations seem to have a non-specific effect on bacterial membranes in absence of pEtN-cellulose. We subsequently conducted similar experiments on purified curli or pEtN-cellulose fibres. The spectra of the pEtN-cellulose fibres revealed a non-valence-specific interaction between metal cations and the phosphate of the pEtN-modification. Altogether, these results demonstrate that the mechanical properties of E. coli biofilms can be tuned via incubation with metal ions. While the mechanism involving curli fibres remains to be determined, metal cations seem to adsorb onto pEtN-cellulose and this is not valence-specific. This work also underlines the importance of matrix architecture to biofilm mechanics and emphasises the specificity of each matrix composition.}, language = {en} } @phdthesis{ConradStrickling2023, author = {Conrad-Strickling, G{\"u}nter}, title = {Ausschnitte des konfliktreichen Welttheaters}, school = {Universit{\"a}t Potsdam}, pages = {182}, year = {2023}, abstract = {Zielsetzung und leitendes Erkenntnisinteresse Als Arbeitsgrundlage soll folgende Definition der B{\"u}hnengesellschaft als Ausgangspunkt dienen: Die B{\"u}hnengesellschaft wird durch die Gesamtzahl der handelnden Personen einer Posse gebildet, die in einem sozialen, psychologischen und mentalen Beziehungsverh{\"a}ltnis zueinanderstehen. Ihr Umfang ist sowohl von gattungsspezifischen als auch von theaterpraktischen Faktoren abh{\"a}ngig. Die B{\"u}hnengesellschaft bildet die Schnittstelle zwischen der fiktionalen Welt der Posse und der Lebenswirklichkeit der Zuschauer. Sie verbindet Spielwelt und Wirklichkeit. Durch diese Br{\"u}ckenfunktion werden beide Elemente aufeinander bezogen. Der so umrissene Blick muss bei der Analyse der B{\"u}hnengesellschaft von Nestroys Possen folgende unterschiedlich gewichtete und akzentuierte Schwerpunkte enthalten: 1. Figurenkonzeption Die Konzeption der Figuren der Nestroyschen B{\"u}hnengesellschaften wird sowohl im Kontext der historischen Wirklichkeit und den herrschenden kulturellen Konzepten als auch in Bezug zur Gattungstradition analysiert unter der erkenntnisleitenden Fragestellung, wie Zeitwirklichkeit („das konfliktreiche Welttheater") erfahrbar wird. Der Analyse der „komischen Zentralfigur" kommt in diesem Zusammenhang eine besondere Bedeutung zu. 2. B{\"u}hnengesellschaftliche Beziehungen Eine Analyse der Figurenkonstellation, des Verh{\"a}ltnisses von Haupt- und Nebenfiguren sowie der Bildung von Gruppierungen erhellt ihre dramaturgische Funktion im Kontext der satirischen Intention. 3. B{\"u}hnengesellschaft und Theater Der theaterwissenschaftliche Aspekt wird dadurch akzentuiert, dass Theaterorganisation, B{\"u}hne und die m{\"a}nnlich-weibliche Zusammensetzung des Ensembles in den Blick genommen werden, um die Abh{\"a}ngigkeit des Umfangs und der Zusammensetzung der B{\"u}hnengesellschaft von den realen Gegebenheiten des Volkstheaterbetriebs aufzuzeigen. Auf der Grundlage der genannten Schwerpunkte wird f{\"u}r die Untersuchung folgendes leitendes Erkenntnisinteresse formuliert: Die B{\"u}hnengesellschaft besitzt eine Schnittstellenfunktion zwischen der fiktionalen Spielwelt der Posse und der Lebenswirklichkeit der Zuschauerschaft. Durch die Analyse der personellen und strukturellen Gestaltung der B{\"u}hnengesellschaft wird ihre Br{\"u}ckenfunktion f{\"u}r die ‚Wirksamkeit' der satirischen und parodistischen Intention erhellt.}, language = {de} } @phdthesis{Kairaliyeva2023, author = {Kairaliyeva, Talmira}, title = {Surfactant adorption at liquid interfaces measured by drop and bubble experiments}, school = {Universit{\"a}t Potsdam}, pages = {VII, 117}, year = {2023}, language = {en} } @phdthesis{Lukosek2023, author = {Lukosek, Sandra}, title = {Vereine als Gefahr}, series = {Beitr{\"a}ge zum Sicherheitsrecht und zur Sicherheitspolitik}, volume = {12}, journal = {Beitr{\"a}ge zum Sicherheitsrecht und zur Sicherheitspolitik}, publisher = {Mohr Siebeck}, address = {T{\"u}bingen}, isbn = {978-3-16-161409-5}, issn = {2568-731X}, doi = {10.1628/978-3-16-161410-1}, pages = {XXVIII, 323}, year = {2023}, abstract = {Die von kriminellen oder extremistischen Gruppen ausgehende Gefahr erh{\"o}ht sich entsprechend ihres Organisationsgrades. Eine Zustandsanalyse des Vereinsrechts zeigt, dass Vereins- und Kennzeichenverbote wirkm{\"a}chtige pr{\"a}emptive Maßnahmen gegen neue dezentrale oder mehrstufige Vereinigungen bleiben. Bei ihrer Weiterentwicklung lenkt Sandra Lukosek den Blick auf die Auslegung und wechselseitige Zurechnung verbotsrelevanten Verhaltens einzelner Mitglieder zum Verein und der Erstreckung auf gleichrangige Schwestervereine. Anhand des Waffenrechts arbeitet sie umgekehrt die Vereinszugeh{\"o}rigkeit als taugliches Wesensmerkmal der Mitglieder heraus. Sie betrachtet verschiedene Vereinstypen mit zu differenzierenden vereinigungsfreiheitlichen Schutzbereichen. Ein Verbot religi{\"o}ser islamistisch-extremistischer Vereine unterscheidet sich vom Verbot eines Rocker- oder Reichsb{\"u}rgervereins. Die Autorin l{\"a}sst sich auf sicherheitsbeh{\"o}rdliche Herausforderungen ein und findet praktikable Reformans{\"a}tze zur Fortentwicklung des Vereinsrechts.}, language = {de} } @phdthesis{Gaetjen2023, author = {G{\"a}tjen, Dominic}, title = {A Pichia pastoris surface display system for the efficient screening of high-producing antibody clones}, school = {Universit{\"a}t Potsdam}, pages = {120}, year = {2023}, abstract = {Pichia pastoris (syn. Komagataella phaffi) is a distinguished expression system widely used in industrial production processes. Recent molecular research has focused on numerous approaches to increase recombinant protein yield in P. pastoris. For example, the design of expression vectors and synthetic genetic elements, gene copy number optimization, or co-expression of helper proteins (transcription factors, chaperones, etc.). However, high clonal variability of transformants and low screening throughput have hampered significant success. To enhance screening capacities, display-based methodologies inherit the potential for efficient isolation of producer clones via fluorescence-activated cell sorting (FACS). Therefore, this study focused on developing a novel clone selection method that is based on the non-covalent attachment of Fab fragments on the P. pastoris cell surface to be applicable for FACS. Initially, a P. pastoris display system was developed, which is a prerequisite for the surface capture of secreted Fabs. A Design of Experiments approach was applied to analyze the influence of various genetic elements on antibody fragment display. The combined P. pastoris formaldehyde dehydrogenase promoter (PFLD1), Saccharomyces cerevisiae invertase 2 signal peptide (ScSUC2), - agglutinin (ScSAG1) anchor protein, and the ARS of Kluyveromyces lactis (panARS) conferred highest display levels. Subsequently, eight single-chain variable fragments (scFv) specific for the constant part of the Fab heavy or light chain were individually displayed in P. pastoris. Among the tested scFvs, the anti-human CH1 IgG domain scFv allowed the most efficient Fab capture detected by flow cytometry. Irrespective of the Fab sequence, exogenously added as well as simultaneously secreted Fabs were successfully captured on the cell surface. Furthermore, Fab secretion capacities were shown to correlate to the level of surface-bound Fabs as demonstrated for characterized producer clones. Flow-sorted clones presenting high amounts of Fabs showed an increase in median Fab titers (factor of 21 to 49) compared to unsorted clones when screened in deep-well plates. For selected candidates, improved functional Fab yields of sorted cells vs. unsorted cells were confirmed in an upscaled shake flask production. Since the scFv capture matrix was encoded on an episomal plasmid with inherently unstable autonomously replicating sequences (ARS), efficient plasmid curing was observed after removing the selective pressure. Hence, sorted clones could be immediately used for production without the need to modify the expression host or vector. The resulting switchable display/secretion system provides a streamlined approach for the isolation of Fab producers and subsequent Fab production.}, language = {en} } @phdthesis{Knoll2023, author = {Knoll, Wolf-R{\"u}diger}, title = {Die Treuhandanstalt in Brandenburg}, series = {Studie zur Geschichte der Treuhandandstalt}, journal = {Studie zur Geschichte der Treuhandandstalt}, publisher = {Ch. Links}, address = {Berlin}, isbn = {978-3-96289-173-2}, school = {Universit{\"a}t Potsdam}, pages = {703}, year = {2023}, language = {de} } @phdthesis{Werberg2023, author = {Werberg, Dennis}, title = {Der Stahlhelm - Bund der Frontsoldaten}, series = {Zeitalter der Weltkriege}, volume = {25}, journal = {Zeitalter der Weltkriege}, publisher = {de Gruyter}, address = {Berlin}, isbn = {978-3-11-108234-9}, issn = {2569-7145}, doi = {10.1515/9783111147567}, school = {Universit{\"a}t Potsdam}, pages = {X, 407}, year = {2023}, abstract = {Als eine der großen Veteranenorganisationen und rechte Sammlungsbewegung war der "Stahlhelm - Bund der Frontsoldaten" ein bedeutender politischer Akteur der Weimarer Republik. Er stand in einem {\"a}ußerst ambivalenten Verh{\"a}ltnis zum aufstrebenden Nationalsozialismus. Einerseits konkurrierten sie um die Vorherrschaft innerhalb des nationalen Lagers, andererseits erkannten beide Seiten den Nutzen einer Kooperation. Insbesondere den einfachen Stahlhelm-Mitgliedern erschien die NS-Bewegung als attraktive Alternative, die ihre Ziele zu erreichen schien. Die Konkurrenz steigerte sich 1931/32 zur erbitterten Feindschaft. Nach der Eingliederung eines Großteils der Bundesmitglieder in die SA im Jahr 1933 sah sich der Rest-Bund immer heftigeren Repressalien ausgesetzt, bevor er 1935 aufgel{\"o}st wurde. 1951 neu gegr{\"u}ndet, konnte er nicht an seine fr{\"u}heren Erfolge ankn{\"u}pfen. Mehrere Spaltungen beschleunigten den Niedergang der Organisation.}, language = {de} } @phdthesis{Sihler2023, author = {Sihler, Michael}, title = {Der Austritt aus wichtigem Grund im Personengesellschaftsrecht}, series = {Studien zum Handels-, Arbeits- und Wirtschaftsrecht}, volume = {215}, journal = {Studien zum Handels-, Arbeits- und Wirtschaftsrecht}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-8487-7602-3}, school = {Universit{\"a}t Potsdam}, pages = {215}, year = {2023}, language = {de} } @phdthesis{Kotz2022, author = {Kotz, Maximilian}, title = {The economic costs of climate change}, school = {Universit{\"a}t Potsdam}, pages = {279}, year = {2022}, language = {en} } @phdthesis{Apriyanto2023, author = {Apriyanto, Ardha}, title = {Analysis of starch metabolism in source and sink tissue of plants}, school = {Universit{\"a}t Potsdam}, pages = {166}, year = {2023}, abstract = {Starch is an essential biopolymer produced by plants. Starch can be made inside source tissue (such as leaves) and sink tissue (such as fruits and tubers). Nevertheless, understanding how starch metabolism is regulated in source and sink tissues is fundamental for improving crop production. Despite recent advances in the understanding of starch and its metabolism, there is still a knowledge gap in the source and sink metabolism. Therefore, this study aimed to summarize the state of the art regarding starch structure and metabolism inside plants. In addition, this study aimed to elucidate the regulation of starch metabolism in the source tissue using the leaves of a model organism, Arabidopsis thaliana, and the sink tissue of oil palm (Elaeis guineensis) fruit as a commercial crop. The research regarding the source tissue will focus on the effect of the blockage of starch degradation on the starch parameter in leaves, especially in those of A. thaliana, which lack both disproportionating enzyme 2 (DPE2) and plastidial glucan phosphorylase 1 (PHS1) (dpe2/phs1). The additional elimination of phosphoglucan water dikinase (PWD), starch excess 4 (SEX4), isoamylase 3 (ISA3), and disproportionating enzyme 1 (DPE1) in the dpe2/phs1 mutant background demonstrates the alteration of starch granule number per chloroplast. This study provides insights into the control mechanism of granule number regulation in the chloroplast. The research regarding the sink tissue will emphasize the relationship between starch metabolism and the lipid metabolism pathway in oil palm fruits. This study was conducted to observe the alteration of starch parameters, metabolite abundance, and gene expression during oil palm fruit development with different oil yields. This study shows that starch and sucrose can be used as biomarkers for oil yield in oil palms. In addition, it is revealed that the enzyme isoforms related to starch metabolism influence the oil production in oil palm fruit. Overall, this thesis presents novel information regarding starch metabolism in the source tissue of A.thaliana and the sink tissue of E.guineensis. The results shown in this thesis can be applied to many applications, such as modifying the starch parameter in other plants for specific needs.}, language = {en} } @phdthesis{Jochmaring2023, author = {Jochmaring, Julian}, title = {Negative Ambientalit{\"a}t}, series = {Reihe des Brandenburgischen Zentrums f{\"u}r Medienwissenschaften - ZeM : Monographie}, volume = {2}, journal = {Reihe des Brandenburgischen Zentrums f{\"u}r Medienwissenschaften - ZeM : Monographie}, publisher = {Kadmos}, address = {Berlin}, isbn = {978-3-86599-519-3}, pages = {331}, year = {2023}, language = {de} } @phdthesis{Dixit2023, author = {Dixit, Sneha}, title = {Tension-induced conformational changes of the Piezo protein-membrane nano-dome}, school = {Universit{\"a}t Potsdam}, pages = {94}, year = {2023}, abstract = {Mechanosensation is a fundamental biological process that provides the basis for sensing touch and pain as well as for hearing and proprioception. A special class of ion-channel proteins known as mechanosensitive proteins convert the mechanical stimuli into electrochemical signals to mediate this process. Mechanosensitive proteins undergo conformational changes in response to mechanical force, which eventually leads to the opening of the proteins' ion channel. Mammalian mechanosensitive proteins remained a long sought-after mystery until 2010 when a family of two proteins - Piezo1 and Piezo2 - was identifed as mechanosensors [1]. The cryo-EM structures of Piezo1 and Piezo2 protein were resolved in the last years and reveal a propeller-shaped homotrimer with 114 transmembrane helices [2, 3, 4, 5]. The protein structures are curved and have been suggested to deform the surrounding membrane into a nano-dome, which mechanically responds to membrane tension resulting from external forces [2]. In this thesis, the conformations of membrane-embedded Piezo1 and Piezo2 proteins and their tension-induced conformational changes are investigated using molecular dynamics simulations. Our coarse-grained molecular dynamics simulations show that the Piezo proteins induce curvature in the surrounding membrane and form a stable protein-membrane nano-dome in the tensionless membrane. These membrane-embedded Piezo proteins, however, adopt substantially less curved conformations in our simulations compared to the cryo-EM structures solved in detergent micelles, which agrees with recent experimental investigations of the overall Piezo nano-dome shape in membrane vesicles [6, 7, 8]. At high membrane tension, the Piezo proteins attain nearly planar conformations in our simulations. Our systematic investigation of Piezo proteins under different membrane tensions indicates a half-maximal conformational response at membrane tension values rather close to the experimentally suggested values of Piezo activation [9, 10]. In addition, our simulations indicate a widening of the Piezo1 ion channel at high membrane tension, which agrees with the channel widening observed in recent nearly flattened cryo-EM structures of Piezo1 in small membrane vesicles [11]. In contrast, the Piezo2 ion channel does not respond to membrane tension in our simulations. These different responses of the Piezo1 and Piezo2 ion channels in our simulations are in line with patch-clamp experiments, in which Piezo1, but not Piezo2, was shown to be activated by membrane tension alone [12].}, language = {en} } @phdthesis{HashemiRanjbar2023, author = {Hashemi Ranjbar, Seirana}, title = {Plasticity and trade-offs in plant metabolic networks}, school = {Universit{\"a}t Potsdam}, pages = {112}, year = {2023}, abstract = {A biological trade-off situation denotes the dependence between traits whereby an increase in the value of one of the traits leads to a decrease in the value of at least one of the others. Understanding trade-offs in cellular systems is relevant to understanding the limits and constraints to tuning desired phenotypes. Therefore, it is mainly the case for rates (i.e. fluxes) of biochemical reactions that shape not only molecular traits, like metabolite concentrations but also determine physiological traits, like growth. Intracellular fluxes are the final phenotype from transcriptional and (post)translational regulation. Quantifying intracellular fluxes provides insights into cellular physiology under particular growth conditions and can be used to characterize the metabolic activity of different pathways. However, estimating fluxes from labelling experiments is labour-intensive; therefore, developing approaches to accurately and precisely predict intracellular fluxes is essential. This thesis addresses two main problems: (i) identifying flux trade-offs and (ii) predicting accurate and precise reaction flux at a genome-scale level. To this end, the concept of an absolute flux trade-off is defined, and a constraint-based approach, termed FluTO, was developed to identify absolute flux trade-offs. FluTO is cast as a mixed integer programming approach applied to genome-scale metabolic models of E. coli, S. cerevisiae, and A. thaliana, imposing realistic constraints on growth and nutrient uptake.. The findings showed that trade-offs are not only species-specific but also specific to carbon sources. In addition, we found that different models of a single species have a different number of reactions in trade-offs. We also showed that absolute flux trade-offs depend on the biomass reaction used to model the growth of A. thaliana under different carbon and nitrogen conditions. Findings reflect the strong relation between nitrogen, carbon, and sulphur metabolisms in the leaves of C3 plants. The concept of relative trade-offs was introduced to further study trade-offs in metabolic networks. A constraint-based approach, FluTOr, was proposed to identify reactions whose fluxes are in relative trade-off concerning an optimized fitness-related cellular task, like growth. FluTOr was employed to find the relative flux trade-offsin the genome-scale metabolic networks of E. coli, S. cerevisiae, and A. thaliana. The results showed that in contrast to the A. thaliana model, the relative trade-offs in the two microorganisms depend on the carbon source, reflecting the differences in the underlying metabolic network. Furthermore, applying FluTOr also showed that reactions that participated in relative trade-offs were implicated in cofactor biosynthesis in the two microorganisms. Prediction of reaction fluxes in the constraint-based metabolic framework is usually performed by parsimonious flux balance analysis (pFBA), employing the principle of efficient usage of protein resources. However, we argued that principles related to the coordination of flux values, neglected in previous studies, provide other means to predict intracellular fluxes. To this end, we designed a constraint-based approach, termed complex-balanced FBA (cbFBA), to predict steady-state flux distributions that maximize the number of balanced complexes in a flux distribution, whereby multi-reaction dependencies are maximized. The comparative analysis showed a better agreement of the flux distributions resulting from cbFBA compared to pFBA with experimentally measured fluxes from 17 E. coli strains and 26 S. cerevisiae knock-out mutants. The results also showed that the predictions from cbFBA are more precise than those from pFBA since cbFBA results in a smaller space of alternative solutions than pFBA.}, language = {en} } @phdthesis{Shen2022, author = {Shen, Yawen}, title = {Functional characterization of the gene regulatory network of C2H2-type zine finger protein ZAT8 in Arabidopsis thaliana}, pages = {124}, year = {2022}, language = {en} } @phdthesis{Mende2023, author = {Mende, Christiane}, title = {Spur der Scherben}, series = {1800 | 2000. Kulturgeschichten der Moderne ; 13}, journal = {1800 | 2000. Kulturgeschichten der Moderne ; 13}, publisher = {transcript}, address = {Bielefeld}, isbn = {978-3-8376-6303-7}, issn = {2747-383X}, doi = {10.1515/9783839463031}, pages = {778}, year = {2023}, language = {de} } @phdthesis{Rolo2023, author = {Rolo, David}, title = {Assembly of photosystem I in thylakoid membranes}, school = {Universit{\"a}t Potsdam}, pages = {177}, year = {2023}, abstract = {The light reactions of photosynthesis are carried out by a series of multiprotein complexes embedded in thylakoid membranes. Among them, photosystem I (PSI), acting as plastocyanin-ferderoxin oxidoreductase, catalyzes the final reaction. Together with light-harvesting antenna I, PSI forms a high-molecular-weight supercomplex of ~600 kDa, consisting of eighteen subunits and nearly two hundred co-factors. Assembly of the various components into a functional thylakoid membrane complex requires precise coordination, which is provided by the assembly machinery. Although this includes a small number of proteins (PSI assembly factors) that have been shown to play a role in the formation of PSI, the process as a whole, as well as the intricacy of its members, remains largely unexplored. In the present work, two approaches were used to find candidate PSI assembly factors. First, EnsembleNet was used to select proteins thought to be functionally related to known PSI assembly factors in Arabidopsis thaliana (approach I), and second, co-immunoprecipitation (Co-IP) of tagged PSI assembly factors in Nicotiana tabacum was performed (approach II). Here, the novel PSI assembly factors designated CO-EXPRESSED WITH PSI ASSEMBLY 1 (CEPA1) and Ycf4-INTERACTING PROTEIN 1 (Y4IP1) were identified. A. thaliana null mutants for CEPA1 and Y4IP1 showed a growth phenotype and pale leaves compared with the wild type. Biophysical experiments using pulse amplitude modulation (PAM) revealed insufficient electron transport on the PSII acceptor side. Biochemical analyses revealed that both CEPA1 and Y4IP1 are specifically involved in PSI accumulation in A. thaliana at the post-translational level but are not essential. Consistent with their roles as factors in the assembly of a thylakoid membrane protein complex, the two proteins localize to thylakoid membranes. Remarkably, cepa1 y4ip1 double mutants exhibited lethal phenotypes in early developmental stages under photoautotrophic growth. Finally, co-IP and native gel experiments supported a possible role for CEPA1 and Y4IP1 in mediating PSI assembly in conjunction with other PSI assembly factors (e.g., PPD1- and PSA3-CEPA1 and Ycf4-Y4IP1). The fact that CEPA1 and Y4IP1 are found exclusively in green algae and higher plants suggests eukaryote-specific functions. Although the specific mechanisms need further investigation, CEPA1 and Y4IP1 are two novel assembly factors that contribute to PSI formation.}, language = {en} } @phdthesis{vonRebay2023, author = {von Rebay, Anna}, title = {The Designation of Marine Protected Areas}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-29174-6}, doi = {10.1007/978-3-031-29175-3}, pages = {XV, 278}, year = {2023}, abstract = {This book provides empirical evidence that all States have a universally binding obligation to adopt national laws and international treaties to protect the marine environment, including the designation of Marine Protected Areas. Chapter by chapter this obligation is detailed, providing the foundation for holding States responsible for fulfilling this obligation. The fundamentals are analysed in a preliminary chapter, which examines the legally binding sources of the Law of the Sea as well as its historical development to help readers understand the key principles at hand. The Law of the Sea provides more than 1000 instruments and more than 300 regulations concerning marine protection. While the scope of most treaties is limited either regarding species, regions or activities, one regulation addresses States in all waters: the obligation to protect and preserve the marine environment as stipulated under Art. 192 of the 1982 United Nations Convention on the Law of the Sea (UNCLOS). As this 'Constitution of the Ocean' not only contains conventional laws but also very broadly reflects pre-existing rules of customary international law, an extensive analysis of all statements made by States in the UN General Assembly, their practices, national laws and regulations as well as other public testimonials demonstrates that Art. 192 UNCLOS indeed binds the whole community of States as a rule of customary international law with an erga omnes effect. Due to the lack of any objections and its fundamental value for humankind, this regulation can also be considered a new peremptory norm of international law (ius cogens). While the sovereign equality of States recognises States' freedom to decide if and how to enter into a given obligation, States can also waive this freedom. If States accepted a legally binding obligation, they are thus bound to it. Concerning the specific content of Art. 192 UNCLOS, a methodical interpretation concludes that only the adoption of legislative measures (national laws and international agreements) suffices to comply with the obligation to protect and preserve the marine environment, which is confirmed by the States' practices and relevant jurisprudence. When applied to a specific geographical area, legislative measures to protect the marine environment concur with the definition of Marine Protected Areas. Nonetheless, as the obligation applies to all waters, the Grotian principle of the freedom of the sea dictates that the restriction of activities through the designation of Marine Protected Areas, on the one hand, must be weighed against the freedoms of other States on the other. To anticipate the result: while all other rights under the UNCLOS are subject to and contingent on other regulations of the UNCLOS and international law, only the obligation to protect and preserve the marine environment is granted absolutely - and thus outweighs all other interests}, language = {en} } @phdthesis{Kontbay2022, author = {Kontbay, K{\"u}bra}, title = {Nin-Like Protein (NLP) transcription factors}, pages = {113}, year = {2022}, language = {en} } @phdthesis{Wagner2023, author = {Wagner, Luisa}, title = {Diagnosekompetenz (angehender) Lehrkr{\"a}fte}, school = {Universit{\"a}t Potsdam}, pages = {104}, year = {2023}, abstract = {Bereits im vorschulischen Bereich, aber vor allem in der Grundschule entwickeln Kinder wichtige Kompetenzen f{\"u}r sp{\"a}tere Bildungsabschl{\"u}sse. Doch die Kompe-tenzunterschiede zwischen den Sch{\"u}ler:innen sind bereits zu Beginn der Grund-schulzeit betr{\"a}chtlich. Somit kommt den Lehrkr{\"a}ften die {\"u}beraus wichtige Aufga-be zu allen Kindern den f{\"u}r sie besten Bildungsweg zu erm{\"o}glichen. Um dieser Herausforderung zu begegnen, m{\"u}ssen Diagnostik und F{\"o}rderung im Unterricht Hand in Hand gehen. Deshalb wird die Diagnosekompetenz von Lehrkr{\"a}ften als wichtige Voraussetzung f{\"u}r gelingenden Unterricht angesehen. Diese Dissertation widmet sich nun eben dieser wichtigen Kompetenz. Dabei wird sie als mehrdimen-sionales Konstrukt angesehen, zu dem neben der Beurteilung von fachlichen Kompetenzen auch die Einsch{\"a}tzung des Leistungsstandes und die Schlussfolge-rung hinsichtlich notwendiger F{\"o}rderung im Unterricht geh{\"o}ren. Anhand dreier Artikel sowie erg{\"a}nzender theoretischer Betrachtungen wurde die Diagnosekompe-tenz hinsichtlich m{\"o}glicher Einflussfaktoren, der Bedeutung f{\"u}r den Unterricht sowie f{\"u}r die Lehrer:innenbildung untersucht.}, language = {de} } @phdthesis{Akbal2023, author = {Akbal, Zeynep}, title = {Lived-Body Experiences in Virtual Reality}, series = {Digitale Gesellschaft}, volume = {61}, journal = {Digitale Gesellschaft}, publisher = {transcript}, address = {Bielefeld}, isbn = {978-3-8376-6676-2}, school = {Universit{\"a}t Potsdam}, pages = {210}, year = {2023}, language = {en} } @phdthesis{Knoerr2023, author = {Kn{\"o}rr, Kai}, title = {Funken}, series = {Reihe des Brandenburgischen Zentrums f{\"u}r Medienwissenschaften - ZeM}, journal = {Reihe des Brandenburgischen Zentrums f{\"u}r Medienwissenschaften - ZeM}, publisher = {Kadmos}, address = {Berlin}, isbn = {978-3-86599-538-4}, school = {Universit{\"a}t Potsdam}, pages = {237}, year = {2023}, language = {de} } @phdthesis{Ribacki2023, author = {Ribacki, Enrico}, title = {Intra-granitic pegmatites of the Las Chacras-Potrerillos batholith, Argentina}, school = {Universit{\"a}t Potsdam}, pages = {XVIII, 183}, year = {2023}, language = {en} } @phdthesis{John2023, author = {John, Sheeba}, title = {Characterizing the role of Heat Shock Factor HSFA 7b in regulating thermomemory at the SAM in Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {122}, year = {2023}, abstract = {Heat stress (HS) is one of the major abiotic stresses which adversely affects the survival and growth of plants due to their sessile nature. To combat the detrimental effects of HS and develop thermotolerance, plants have evolved several defense mechanisms. Thermomemory is one such molecular mechanism whereby plants that have been acclimated (or primed/P) by a moderate HS can respond more efficiently and continue their growth after exposure to a severe or lethal HS (called triggering/T), while unprimed plants cannot survive. Thermomemory is known to be regulated by several transcription factors (TFs), epigenetic changes, chromatin remodellers, post-transcriptional changes and it also involves protein stability control and primary metabolism adjustment. Recent research has suggested that the shoot apical meristem (SAM) in Arabidopsis thaliana has a distinct transcriptional thermomemory which is possibly regulated by eight TFs called HEAT SHOCK FACTORS (HSFs). The main objective of this PhD thesis is to investigate the role of HSFA7b (one of the eight HSFs), in regulating thermomemory at the SAM by identifying the molecular networks it regulates. HSFA7a, a close homolog of HSFA7b, is also one of the eight HSFs that are involved in regulating thermomemory at the SAM. Thermomemory was found to be defective in the hsfa7b and hsfa7a hsfa7b mutants; the percentage survival of these seedlings was significantly lower than in wild-type (WT) seedlings after the priming and triggering (PT) treatment. Transcriptome and ChIP analyses were performed to identify the molecular networks controlled by HSFA7b and its close homolog HSFA7a, in regulating thermomemory at the SAM. The chromatin regulator SPLAYED (SYD) was found to be regulated by both HSFA7a and HSFA7b at the SAM during thermomemory. SYD is directly involved in SAM maintenance by directly regulating WUSCHEL (WUS), a master regulator of stem cell maintenance. WUS expression was down-regulated at the SAM of PT treated hsfa7a/b mutants compared to WT-Col-0 seedlings. HSFA7a and HSFA7b also jointly regulate the expression of orphan gene QUA QUINE STARCH (QQS) during thermomemory. Starch accumulation negatively correlates with QQS expression and this trend was observed in WT plants in response to thermopriming. The remobilization of starch was affected in the hsfa7a/b mutants compared to WT plants during the recovery period after T treatment. These findings indicate that defects in SAM maintenance and starch remobilization could possibly contribute to the reduced thermomemory in the hsfa7a/b mutants. Moreover, transcriptome and ChIP analysis indicate that ethylene signaling genes are directly regulated by HSFA7b during thermomemory. Transcriptome analysis of the HSFA7b-IOE line indicates that HSFA7b positively regulates the expression of HEAT STRESS ASSOCIATED 32 (HSA32), an important thermomemory gene, and HSFA7b strongly suppresses the expression of the reactive oxygen species (ROS) responsive REDOX RESPONSIVE TRANSCRIPTION FACTOR 1 (RRTF1) gene, which is also a repressed target of SYD. In Arabidopsis, the HSFA7b transcript undergoes alternative splicing at high temperatures to form two splice variants: one correctly/constitutively spliced variant which is functional and codes for the HSFA7b protein and one intron retained splice variant. Higher accumulation of the functional HSFA7b splice variant was found at the SAM compared to other tissues. Moreover, accumulation of the functional splice variant was higher in P and PT plants compared to control plants, whereas higher levels of the intron retained splice variant is found in plants subjected directly to the T treatment. The intron retained HSFA7b splice variant is degraded by the non-sense mediated decay (NMD) pathway as a means of regulating transcript level essential for protein synthesis at high temperatures. Importantly, HSFA7b protein accumulation was observed in plants subjected to PT treatment that survive and continue growth, but not in plants subjected directly to T treatment that do not survive, indicating that constitutive/ correct splicing of the HSFA7b transcript is a component of thermomemory. Taken together, these findings suggest that HSFA7a and HSFA7b jointly regulate SAM maintenance via the chromatin remodeller SYD and starch remobilization via QQS. In addition to them, HSFA7b also regulates the expression of ethylene signaling genes, heat responsive genes and the ROS responsive RRTF1. Furthermore, constitutive/correct splicing in the HSFA7b transcript is also an essential component of thermomemory.}, language = {en} } @phdthesis{vonBismarck2023, author = {von Bismarck, Thekla}, title = {The influence of long-term light acclimation on photosynthesis in dynamic light}, school = {Universit{\"a}t Potsdam}, pages = {x, 163}, year = {2023}, abstract = {Photosynthesis converts light into metabolic energy which fuels plant growth. In nature, many factors influence light availability for photosynthesis on different time scales, from shading by leaves within seconds up to seasonal changes over months. Variability of light energy supply for photosynthesis can limit a plant´s biomass accumulation. Plants have evolved multiple strategies to cope with strongly fluctuation light (FL). These range from long-term optimization of leaf morphology and physiology and levels of pigments and proteins in a process called light acclimation, to rapid changes in protein activity within seconds. Therefore, uncovering how plants deal with FL on different time scales may provide key ideas for improving crop yield. Photosynthesis is not an isolated process but tightly integrates with metabolism through mutual regulatory interactions. We thus require mechanistic understanding of how long-term light acclimation shapes both, dynamic photosynthesis and its interactions with downstream metabolism. To approach this, we analyzed the influence of growth light on i) the function of known rapid photosynthesis regulators KEA3 and VCCN1 in dynamic photosynthesis (Chapter 2-3) and ii) the interconnection of photosynthesis with photorespiration (PR; Chapter 4). We approached topic (i) by quantifying the effect of different growth light regimes on photosynthesis and photoprotection by using kea3 and vccn1 mutants. Firstly, we found that, besides photosynthetic capacity, the activities of VCCN1 and KEA3 during a sudden high light phase also correlated with growth light intensity. This finding suggests regulation of both proteins by the capacity of downstream metabolism. Secondly, we showed that KEA3 accelerated photoprotective non-photochemical quenching (NPQ) kinetics in two ways: Directly via downregulating the lumen proton concentration and thereby de-activating pH-dependent NPQ, and indirectly via suppressing accumulation of the photoprotective pigment zeaxanthin. For topic (ii), we analyzed the role of PR, a process which recycles a toxic byproduct of the carbon fixation reactions, in metabolic flexibility in a dynamically changing light environment. For this we employed the mutants hpr1 and ggt1 with a partial block in PR. We characterized the function of PR during light acclimation by tracking molecular and physiological changes of the two mutants. Our data, in contrast to previous reports, disprove a generally stronger physiological relevance of PR under dynamic light conditions. Additionally, the two different mutants showed pronounced and distinct metabolic changes during acclimation to a condition inducing higher photosynthetic activity. This underlines that PR cannot be regarded purely as a cyclic detoxification pathway for 2PG. Instead, PR is highly interconnected with plant metabolism, with GGT1 and HPR1 representing distinct metabolic modulators. In summary, the presented work provides further insight into how energetic and metabolic flexibility is ensured by short-term regulators and PR during long-term light acclimation.}, language = {en} } @phdthesis{Rasul2023, author = {Rasul, Fiaz}, title = {Biostimulant SuperFifty based molecular priming to increase plant strength and stress tolerance}, year = {2023}, language = {en} } @phdthesis{Berg2023, author = {Berg, Carsten}, title = {Der Beitrag der europ{\"a}ischen B{\"u}rgerinitiative zur Demokratisierung der Europ{\"a}ischen Union}, pages = {387}, year = {2023}, abstract = {Der Untersuchungsgegenstand der vorliegenden Arbeit ist die Praxis der Europ{\"a}ischen B{\"u}rgerinitiative (EBI) nach Art. 11 Abs. 4 EUV, dem weltweit ersten und einzigen Instrument transnationaler, partizipativer und digitaler Demokratie. Im Mittelpunkt der Untersuchung steht die Frage, welchen Beitrag die EBI zur weiteren Demokratisierung der EU leisten kann und auf welche Art und Weise insoweit noch weitere Verbesserungen erzielt werden k{\"o}nnen. Nach zehnj{\"a}hriger Anwendungspraxis von 2012 bis 2022 liegen inzwischen ausreichend empirische Daten vor, um den Forschungsgegenstand umfassend zu erforschen und das Instrument mit Blick auf seinen von den EU-Institutionen versprochenen Legitimations- und Demokratisierungsbeitrag bewerten zu k{\"o}nnen. Insbesondere wird das EBI-Verfahren in dieser Arbeit auf seine empirisch nachweisbare Nutzung, auf seine prozedurale Nutzerfreundlichkeit sowie auf seine politische wie rechtliche Wirkm{\"a}chtigkeit untersucht. Zum Zwecke der korrekten Kategorisierung, Bewertung sowie der nutzerfreundlichen Ausgestaltung des EBI-Verfahrens werden Vergleiche mit B{\"u}rger- und Volksinitiativverfahren in den EU-Mitgliedstaaten sowie mit B{\"u}rgerbeteiligungsverfahren auf EU-Ebene vorgenommen. Den empirischen und komparativen Analysen werden eine historische Analyse {\"u}ber die Genese der EBI seit dem EU-Verfassungskonvent sowie theoretisch-normative {\"U}berlegungen und praktische Untersuchungen zu unterschiedlichen beteiligungszentrierten Demokratiemodellen vorangestellt, um die EBI einzuordnen und die Steigerungsm{\"o}glichkeiten ihres Demokratisierungsbeitrags zu erschließen. Letzteres zielt schließlich auf die Frage nach der prozeduralen Kombination und Kompatibilit{\"a}t der EBI mit demokratischen Innovationen aus dem Bereich der deliberativen und direkten Demokratie ab. Die Arbeit schließt mit einem Ausblick und unterbreitet umfassende EBI-Reformoptionen sowohl auf der prim{\"a}r- und sekund{\"a}rrechtlichen als auch auf der informellen Ebene.}, language = {de} } @phdthesis{Zakrzewski2023, author = {Zakrzewski, Tanja}, title = {Identity and violence in early modern Granada}, series = {Lexington studies in modern Jewish history, historiography, and memory}, journal = {Lexington studies in modern Jewish history, historiography, and memory}, publisher = {Lexington Books}, address = {Lanham}, isbn = {978-1-66691-534-1}, school = {Universit{\"a}t Potsdam}, pages = {VII, 245}, year = {2023}, language = {en} } @phdthesis{Teitscheid2023, author = {Teitscheid, Jana}, title = {Information and communication technologies usage and the effects on the human mind}, school = {Universit{\"a}t Potsdam}, pages = {XII, 228}, year = {2023}, abstract = {The digitization has permeated almost all aspects of an individual's life. In the work context as well as in the private sphere, one readily encounters and relies on Information and Communication Technologies (ICTs), such as Social Networking Sites (SNS), smartphones and so forth. By communicating with as well as obtaining information via such technologies, ICTs engage one's mind as interaction happens. This interaction of ICTs and the human mind form the focal topic of this thesis. Within this thesis, the human mind is represented on behalf of a facilitated model comprising a perceptual, a cognitive and a motor subsystem. ICTs represent an external stimulus, which triggers the human mind's perceptual subsystem, the cognitive subsystem and eventually leads to a motoric response via the motor subsystem. The external stimulus causing this event chain is within this thesis an ICT. The digital environment and related ICTs are high attention environments offering large and easily accessible amounts of information. Not surprisingly, issues may arise, when the human mind deals with ICTs. Thus, the interplay between ICTs and the human mind entails downsides. This thesis investigates these downsides and in addition the ICT-based factors that cause these downsides. More specifically, the thesis investigates these two aspects as research questions in the context of SNSs as well as other ICTs (such as smartphones, e-learning etc.). Addressing the research questions, 8 articles are submitted within this thesis which address the topic with different methodologies, including quantitative, qualitative, mixed methods as well as systematic literature reviews. Article 1 investigates factors that lead to SNS fatigue and discontinuance intentions in a mixed-methods design. Article 2 explores if certain factors encountered on a newsfeed hamper sensemaking. Article 3 proposes a study design to explore the link between disorderly perceptions of a SNSs newsfeed and gender stereotype activations. Article 4 considers the interplay between users and algorithms via the newsfeed interface and the implications for relevance perceptions. Article 5 explores information acquisition, hampering factors and verification strategies of social media users. Article 6 systematically reviews addiction scales of various ICTs. Article 7 investigates click behavior in e-learning contexts and how this is linked to cultural and personality traits. Finally, article 8 offers a comprehensive overview of the antecedents and consequences of children's smartphone usage. Within the specific context of SNSs, the thesis suggests that the cognitive tolls imposed on users' minds cause adverse effects, such as impaired sensemaking, fatigue, stereotype activation as well as intentions to discontinue the service. Other ICTs lead to addiction, and i.e., smartphones evidence to cause cognitive impairments in children. Factors on the ICT side that promote these adverse effects are linked to specific features, such as the newsfeed for SNSs and entail overload or perceptions of disorder. The thesis adds theoretically to the understanding of downsides that arise from the interplay between human minds and ICTs. Especially, the context of SNSs is spotlighted and insights add to the growing body of literature on experiences and perceptions. For instance, one study's result suggests that considering information organization is as important as merely decreasing overload perceptions from the users in countering adverse effects of SNS usage. Practically, the thesis emphasizes the importance of mindful interaction with ICTs. Future research is welcome to build on the exploratory investigations and may draw an even more holistic picture to enhance the interaction between ICTs and the human mind.}, language = {en} } @phdthesis{Gramma2023, author = {Gramma, Vladislav}, title = {Potato FLC-like and SVP-like proteins jointly control growth and distinct developmental processes}, school = {Universit{\"a}t Potsdam}, pages = {x, 138}, year = {2023}, abstract = {Based on worldwide consumption, Solanum tuberosum L. (potato) is the most important non-grain food crop. Potato has two ways of stable propagation: sexually via flowering and vegetatively via tuberization. Remarkably, these two developmental processes are controlled by similar molecular regulators and mechanisms. Given that FLC and SVP genes act as key flowering regulators in the model species Arabidopsis and in various other crop species, this study aimed at identifying FLC and SVP homologs in potato and investigating their roles in the regulation of plant development, with a particular focus on flowering and tuberization. Our analysis demonstrated that there are five FLC-like and three SVP like proteins encoded in the potato genome. The expression profiles of StFLCs and StSVPs throughout potato development and the detected interactions between their proteins indicate tissue specificity of the individual genes and distinct roles of a variety of putative protein complexes. In particular, we discovered that StFLC-D, as well as StFLC-B, StSVP-A, and StSVP-B play a complex role in the regulation of flowering time, as not only increased but also decreased levels of their transcripts promote earlier flowering. Most importantly, StFLC-D has a marked impact on tuberization under non-inductive conditions and susceptibility to temperature-induced tuber malformation, also known as second growth. Plants with decreased levels of StFLC-D demonstrated a strong ability to produce tubers under long days and appeared to be insensitive to temperature-induced second growth. Lastly, our data also suggests that StFLCs and StSVPs may be involved in the nitrogen-dependent regulation of potato development. Taken together, this study highlights the functional importance of StFLC and StSVP genes in the regulation of distinct developmental processes in potato.}, language = {en} } @phdthesis{Stork2023, author = {Stork, Carsten}, title = {Organizational negotiation mnagement}, series = {Schriftenreihe zum Verhandlungsmanagement ; 23}, journal = {Schriftenreihe zum Verhandlungsmanagement ; 23}, publisher = {Kovac}, address = {Hamburg}, isbn = {978-3-339-13554-4}, issn = {2365-7898}, pages = {XVII, 168}, year = {2023}, abstract = {Negotiations are a way of joint decision-making and thereby a form of social conflict. By determining the concrete allocation of scarce resources, negotiations have a great impact on the value creation of companies. If companies succeed in achieving better negotiation results in the long term, they can increase their profitability. Ensuring a company's negotiation success is therefore an organizational issue of central importance. While the question of ensuring individual negotiation success has been the subject and topic of multidisciplinary research for a long time, the question of how organizations can implement and ensure continuous negotiation success remains largely unexplored. This dissertation therefore aims to investigate how companies enable their employees to consistently achieve better negotiation outcomes. It is significant that, in the corporate context, negotiators do not act as individuals but as embedded representatives of an organization, and that negotiations are not one-time events but recurring necessities for the existence of the organization instead. In organizations, those recurring processes with a similar fundamental structure are handled by routines. A planned improvement of routines is often forced by new artifacts. In this context, artifacts refer to human-created technologies with which humans interact within routines and therefore artifacts have a central influence on executing the routine. If negotiation activities in companies are represented by organizational routines, one central issue for improving companies' negotiation performance is the artifacts' incorporation into organizational negotiation routines that facilitate the efficient application of the insights from negotiation research. The dissertation consists of three studies that were written as research papers to examine artifacts in the organizational negotiation context. The first study focuses on the pre-negotiation stage and presents four tools to assist negotiation practitioners in efficiently preparing for negotiation. The study examines the negotiation preparation's effectiveness and efficiency and the negotiation outcome in a case-based experiment. The second study is devoted to a closer examination of the barriers that inhibit the adoption of negotiation support systems (NSSs) as one kind of organizational negotiation artifact. The investigation is conducted using a structural equation model based on information from participating practitioners. The third study is concerned with the future of negotiation support system research. An exploratory study based on qualitative in-depth interviews with proven and published experts in the field aims to evaluate the current state of research. The general discussion of the dissertation connects, summarizes, and concludes the study results and derives implications for practice, limitations, and future research ideas.}, language = {en} } @phdthesis{Frank2023, author = {Frank, Bradley D.}, title = {Complex and adaptive soft colloids}, school = {Universit{\"a}t Potsdam}, pages = {XIV, 154}, year = {2023}, language = {en} } @phdthesis{Nikolova2023, author = {Nikolova, Mariya Dimitrova}, title = {How whiteness claimed the future}, series = {American Frictions}, volume = {7}, journal = {American Frictions}, publisher = {De Gruyter}, address = {Berlin}, isbn = {978-3-11-079999-6}, doi = {10.1515/9783110799996}, school = {Universit{\"a}t Potsdam}, pages = {178}, year = {2023}, abstract = {Interested in the ideological workings of fiction, I study how major avant-garde tropes promote the potential of permanent renewal as white America's property. Renewal ties to the capacities to create, progress, transcend, and simply be. From Black critique we know that, within dominant discourse, all these capacities have been denied to Black bodies ever since colonization. Black work has been fetishized, appropriated, stolen, and dismissed in and by dominant culture, while Black being is construed as negativity and barred on the level of ontology. It follows then that racialization operates on multiple levels in the conceptual frame of renewal. I study this conceptualization by re-reading the works of and criticism on progressive white authors. I examine how images of renewal enable the claim on futurity, transformative potential, and movement forward as exclusively white properties. Premised on oppositions between positive capacities and a state of complete incapacitation, these images are often viewed as separate constructions. This project shows that, deriving from white ideology, such representations are symbiotic and simultaneous - the "good" story of white renewal rests on the continual transgression towards Black being.}, language = {en} } @phdthesis{Leer2023, author = {Leer, Marina}, title = {Computational analysis of the effects of ageing and diet on stem cell function and ectopic fat accumulation in the musculoskeletal system}, school = {Universit{\"a}t Potsdam}, pages = {130}, year = {2023}, abstract = {The musculoskeletal system provides support and enables movement to the body, and its deterioration is a crucial aspect of age-related functional decline. Mesenchymal stromal cells (MSCs) play an important role in musculoskeletal homeostasis due to their broad differentiation potentials and their ability to support osteogenic and myogenic tissue maintenance and regeneration. In the bone, MSCs differentiate either into osteochondrogenic progenitors to form osteocytes and chondrocytes, or increasingly with age into adipogenic progenitors which give rise to bone-resident adipocytes. In skeletal muscle, during healthy regeneration MSCs provide regulatory signals that activate local, tissue-specific stem cells, known as satellite cells, which regenerate contractile myofibres. This process involves a significant cross-talk to immune cells stemming from both lymphoid and myeloid lineages. During ageing, muscle-resident MSCs undergo increased adipogenic lineage commitment, causing niche changes that contribute to fatty infiltration in muscles. These shifts in cell populations in bone lead to the loss of osteogenic cells and subsequently osteoporosis, or in muscle to impaired regeneration and to the development of sarcopenia. However, the signals that drive transition of MSCs into their respective cellular fates remain elusive. This thesis aims to elucidate the transcriptional shifts modulating cell states and cell types in musculoskeletal MSC fate determination. Single-cell RNA-sequencing (scRNA-seq) was used to characterise cell type-specific transcript regulation. State-of-the-art bioinformatics tools were combined with different analytical platforms that include both droplet-based scRNA-seq for large heterogeneous populations, and microfluidics-based scRNA-seq to assess small, rare subpopulations. For each platform, distinct computational pipelines were established including filtering steps to exclude low-quality cells, and data visualisation was performed by dimensionality reduction. Downstream analysis included clustering, cell type annotation, and differential gene expression to investigate transcriptional states in defined cell types during ageing and injury in the muscle and bone. Finally, a novel tool to assess publication activities in defined areas of research for the identified marker genes was developed. The results in the bone indicate that ageing MSCs increasingly commit towards an adipogenic fate at the expense of osteogenic specialisation. The data also suggests that significant cell population shifts of MSC-type fibro-adipogenic progenitors during muscle ageing underlie the pathologies observed in homeostatic and post-injury regenerative conditions. High-throughput visualisation of publication activity for candidate genes enabled more effective biological evaluation of scRNA-seq data. These results expose critical age-related changes in the stem cell niches of skeletal muscle and bone, highlight their respective sensitivity to nutrition and pathology, and elucidate novel factors that modulate stem cell-based regeneration. Targeting these processes might improve musculoskeletal health in the context of ageing and prevent the negative effects of pathological lineage determination.}, language = {en} }