@article{SchmidtKunz2013,
  author    = {Schmidt, Bernd and Kunz, Oliver},
  title     = {Bidirectional cross metathesis and ring-closing metathesis/ring opening of a C-2-symmetric building block: a strategy for the synthesis of decanolide natural products},
  series = {Beilstein journal of organic chemistry},
  volume    = {9},
  journal   = {Beilstein journal of organic chemistry},
  publisher = {Beilstein-Institut zur F{\"o}rderung der Chemischen Wissenschaften},
  address   = {Frankfurt, Main},
  issn      = {1860-5397},
  doi       = {10.3762/bjoc.9.289},
  pages     = {2544 -- 2555},
  year      = {2013},
  abstract  = {Starting from the conveniently available ex-chiral pool building block (R,R)-hexa-1,5-diene-3,4-diol, the ten-membered ring lactones stagonolide E and curvulide A were synthesized using a bidirectional olefin-metathesis functionalization of the terminal double bonds. Key steps are (i) a site-selective cross metathesis, (ii) a highly diastereoselective extended tethered RCM to furnish a (Z,E)-configured dienyl carboxylic acid and (iii) a Ru-lipase-catalyzed dynamic kinetic resolution to establish the desired configuration at C9. Ring closure was accomplished by macrolactonization. Curvulide A was synthesized from stagonolide E through Sharpless epoxidation.},
  language  = {en}
}