@phdthesis{Shivanand2015, author = {Shivanand, Lathe Rahul}, title = {DUF1068 protein family members are involved in cell wall formation in Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {393}, year = {2015}, language = {en} } @phdthesis{Abon2015, author = {Abon, Catherine Cristobal}, title = {Radar-based rainfall retrieval for flood forecasting in a meso-scale catchment}, school = {Universit{\"a}t Potsdam}, pages = {93 S.}, year = {2015}, language = {en} } @article{SbragagliaLamannaMatetal.2015, author = {Sbragaglia, Valerio and Lamanna, Francesco and Mat, Audrey M. and Rotllant, Guiomar and Joly, Silvia and Ketmaier, Valerio and de la Iglesia, Horacio O. and Aguzzi, Jacopo}, title = {Identification, Characterization, and Diel Pattern of Expression of Canonical Clock Genes in Nephrops norvegicus (Crustacea: Decapoda) Eyestalk}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {11}, publisher = {Public Library of Science}, address = {Lawrence}, issn = {1932-6203}, doi = {10.1371/journal.pone.0141893}, year = {2015}, abstract = {The Norway lobster, Nephrops norvegicus, is a burrowing decapod with a rhythmic burrow emergence (24 h) governed by the circadian system. It is an important resource for European fisheries and its behavior deeply affects its availability. The current knowledge of Nephrops circadian biology is phenomenological as it is currently the case for almost all crustaceans. In attempt to elucidate the putative molecular mechanisms underlying circadian gene regulation in Nephrops, we used a transcriptomics approach on cDNA extracted from the eyestalk, a structure playing a crucial role in controlling behavior of decapods. We studied 14 male lobsters under 12-12 light-darkness blue light cycle. We used the Hiseq 2000 Illumina platform to sequence two eyestalk libraries (under light and darkness conditions) obtaining about 90 millions 100-bp paired-end reads. Trinity was used for the de novo reconstruction of transcriptomes; the size at which half of all assembled bases reside in contigs (N50) was equal to 1796 (light) and 2055 (darkness). We found a list of candidate clock genes and focused our attention on canonical ones: timeless, period, clock and bmal1. The cloning of assembled fragments validated Trinity outputs. The putative Nephrops clock genes showed high levels of identity (blastx on NCBI) with known crustacean clock gene homologs such as Eurydice pulchra (period: 47\%, timeless: 59\%, bmal1: 79\%) and Macrobrachium rosenbergii (clock: 100\%). We also found a vertebrate-like cryptochrome 2. RT-qPCR showed that only timeless had a robust diel pattern of expression. Our data are in accordance with the current knowledge of the crustacean circadian clock, reinforcing the idea that the molecular clockwork of this group shows some differences with the established model in Drosophila melanogaster.}, language = {en} } @article{VormoorLawrenceHeistermannetal.2015, author = {Vormoor, Klaus Josef and Lawrence, D. and Heistermann, Maik and Bronstert, Axel}, title = {Climate change impacts on the seasonality and generation processes of floods}, series = {Hydrology and earth system sciences : HESS}, volume = {19}, journal = {Hydrology and earth system sciences : HESS}, number = {2}, publisher = {Copernicus Publications}, address = {G{\"o}ttingen}, issn = {1027-5606}, doi = {10.5194/hess-19-913-2015}, pages = {913 -- 931}, year = {2015}, abstract = {Climate change is likely to impact the seasonality and generation processes of floods in the Nordic countries, which has direct implications for flood risk assessment, design flood estimation, and hydropower production management. Using a multi-model/multi-parameter approach to simulate daily discharge for a reference (1961-1990) and a future (2071-2099) period, we analysed the projected changes in flood seasonality and generation processes in six catchments with mixed snowmelt/rainfall regimes under the current climate in Norway. The multi-model/multi-parameter ensemble consists of (i) eight combinations of global and regional climate models, (ii) two methods for adjusting the climate model output to the catchment scale, and (iii) one conceptual hydrological model with 25 calibrated parameter sets. Results indicate that autumn/winter events become more frequent in all catchments considered, which leads to an intensification of the current autumn/winter flood regime for the coastal catchments, a reduction of the dominance of spring/summer flood regimes in a high-mountain catchment, and a possible systematic shift in the current flood regimes from spring/summer to autumn/winter in the two catchments located in northern and south-eastern Norway. The changes in flood regimes result from increasing event magnitudes or frequencies, or a combination of both during autumn and winter. Changes towards more dominant autumn/winter events correspond to an increasing relevance of rainfall as a flood generating process (FGP) which is most pronounced in those catchments with the largest shifts in flood seasonality. Here, rainfall replaces snowmelt as the dominant FGP primarily due to increasing temperature.We further analysed the ensemble components in contributing to overall uncertainty in the projected changes and found that the climate projections and the methods for downscaling or bias correction tend to be the largest contributors. The relative role of hydrological parameter uncertainty, however, is highest for those catchments showing the largest changes in flood seasonality, which confirms the lack of robustness in hydrological model parameterization for simulations under transient hydrometeorological conditions.}, language = {en} } @phdthesis{Karo2015, author = {Karo, Nihad Majeed}, title = {Metamorphic evolution of the Northern Zagros Suture Zone (NZSZ)}, school = {Universit{\"a}t Potsdam}, pages = {127}, year = {2015}, language = {en} } @phdthesis{Siegel2015, author = {Siegel, Daniel}, title = {Binary neutron star mergers and short gamma-ray bursts}, school = {Universit{\"a}t Potsdam}, pages = {255}, year = {2015}, language = {en} } @phdthesis{Timofeeva2015, author = {Timofeeva, Nadezda}, title = {Effect of ions and amino-acid sequence on collagen structure}, school = {Universit{\"a}t Potsdam}, pages = {121}, year = {2015}, language = {en} } @incollection{Lottes2014, author = {Lottes, G{\"u}nther}, title = {Language and Content}, series = {Perspectives on English revolutionary republicanism}, booktitle = {Perspectives on English revolutionary republicanism}, publisher = {Ashgate}, address = {Farnham}, publisher = {Universit{\"a}t Potsdam}, pages = {53 -- 61}, year = {2014}, language = {en} } @article{WiemannMahlberg2014, author = {Wiemann, Dirk and Mahlberg, Gaby}, title = {Introduction : Perspectives on English revolutionary republicanism}, series = {Perspectives on English revolutionary republicanism}, journal = {Perspectives on English revolutionary republicanism}, editor = {Wiemann, Dirk and Mahlberg, Gaby}, publisher = {Ashgate}, address = {Farnham}, pages = {1 -- 12}, year = {2014}, language = {en} } @book{WiemannMahlbergDzelzainisetal.2014, author = {Wiemann, Dirk and Mahlberg, Gaby and Dzelzainis, Martin and Cuttica, Cesare and Lottes, G{\"u}nther and Davis, J. C. and Pankratz, Anette and Sedlmayr, Gerold and Vallance, Edward and Vanderbeke, Dirk and Borot, Luc and Champion, Justin and Burgess, Glenn}, title = {Perspectives on English revolutionary republicanism}, editor = {Wiemann, Dirk and Mahlberg, Gaby}, publisher = {Ashgate}, address = {Farnham}, isbn = {978-1-4094-5567-7}, publisher = {Universit{\"a}t Potsdam}, pages = {IX, 228}, year = {2014}, abstract = {Perspectives on English Revolutionary Republicanism takes stock of developments in the scholarship of seventeenth-century English republicanism by looking at the movements and schools of thought that have shaped the field over the decades: the linguistic turn, the cultural turn and the religious turn. While scholars of seventeenth-century republicanism share their enthusiasm for their field, they have approached their subject in diverse ways. The contributors to the present volume have taken the opportunity to bring these approaches together in a number of case studies covering republican language, republican literary and political culture, and republican religion, to paint a lively picture of the state of the art in republican scholarship. The volume begins with three chapters influenced by the theory and methodology of the linguistic turn, before moving on to address cultural history approaches to English republicanism, including both literary culture and (practical) political culture. The final section of the volume looks at how religion intersected with ideas of republican thought. Taken together the essays demonstrate the vitality and diversity of what was once regarded as a narrow topic of political research.}, language = {en} } @phdthesis{Swiadek2015, author = {Swiadek, Magdalena Agnieszka}, title = {Hybrid necrosis in local populations of Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {109}, year = {2015}, language = {en} } @phdthesis{ElKassar2015, author = {El Kassar, Nadja}, title = {Towards a theory of epistemically significant perception}, publisher = {De Gruyter}, address = {Berlin}, isbn = {978-3-11-044563-3}, school = {Universit{\"a}t Potsdam}, pages = {360}, year = {2015}, abstract = {How does perceptual experience make us knowledgeable? This book argues that the answer lies in the nature of perceptual experience: this experience involves conceptual capacities and is a relation between perceiver and world. The author develops her position via a critical examination of conceptualist and relationist theories of perception. A discussion of recent work in vision science rounds up this contribution to the philosophy of perception.}, language = {en} } @phdthesis{Heistermann2015, author = {Heistermann, Maik}, title = {Advancing weather radar in hydrology}, school = {Universit{\"a}t Potsdam}, pages = {228}, year = {2015}, language = {en} } @phdthesis{BaerHenney2015, author = {Baer-Henney, Dinah}, title = {Learners' Little Helper}, school = {Universit{\"a}t Potsdam}, pages = {135}, year = {2015}, language = {en} } @phdthesis{Grune2015, author = {Grune, Jana}, title = {Effects of a novel non-steroidal mineralocorticoid receptor antagonist on cardiac hypertrophy}, school = {Universit{\"a}t Potsdam}, pages = {98}, year = {2015}, language = {en} } @article{MoserTschakertMuelleretal.2015, author = {Moser, Othmar and Tschakert, Gerhard and M{\"u}ller, Alexander and Groeschl, Werner and Pieber, Thomas R. and Obermayer-Pietsch, Barbara and Koehler, Gerd and Hofmann, Peter}, title = {Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {8}, publisher = {Public Library of Science}, address = {Lawrence}, issn = {1932-6203}, doi = {10.1371/journal.pone.0136489}, pages = {17}, year = {2015}, abstract = {Introduction We investigated blood glucose (BG) and hormone response to aerobic high-intensity interval exercise (HIIE) and moderate continuous exercise (CON) matched for mean load and duration in type 1 diabetes mellitus (T1DM). Material and Methods Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A) and above (B) the first lactate turn point and below the second lactate turn point (C) on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/ Novo Nordisk, Denmark). Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25\% (A), 50\% (B), and 75\% (C) dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system. Results BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006) and B (p = 0.004) and respiratory exchange ratio for A (p = 0.003) and B (p = 0.003) were significantly higher compared to CON but not for C. Conclusion Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM.}, language = {en} } @article{JahnBuschmannHille2015, author = {Jahn, Karolina and Buschmann, Volker and Hille, Carsten}, title = {Simultaneous Fluorescence and Phosphorescence Lifetime Imaging Microscopy in Living Cells}, series = {Scientific Reports}, journal = {Scientific Reports}, number = {5}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep14334}, pages = {13}, year = {2015}, abstract = {In living cells, there are always a plethora of processes taking place at the same time. Their precise regulation is the basis of cellular functions, since small failures can lead to severe dysfunctions. For a comprehensive understanding of intracellular homeostasis, simultaneous multiparameter detection is a versatile tool for revealing the spatial and temporal interactions of intracellular parameters. Here, a recently developed time-correlated single-photon counting (TCSPC) board was evaluated for simultaneous fluorescence and phosphorescence lifetime imaging microscopy (FLIM/PLIM). Therefore, the metabolic activity in insect salivary glands was investigated by recording ns-decaying intrinsic cellular fluorescence, mainly related to oxidized flavin adenine dinucleotide (FAD) and the μs-decaying phosphorescence of the oxygen-sensitive ruthenium-complex Kr341. Due to dopamine stimulation, the metabolic activity of salivary glands increased, causing a higher pericellular oxygen consumption and a resulting increase in Kr341 phosphorescence decay time. Furthermore, FAD fluorescence decay time decreased, presumably due to protein binding, thus inducing a quenching of FAD fluorescence decay time. Through application of the metabolic drugs antimycin and FCCP, the recorded signals could be assigned to a mitochondrial origin. The dopamine-induced changes could be observed in sequential FLIM and PLIM recordings, as well as in simultaneous FLIM/PLIM recordings using an intermediate TCSPC timing resolution.}, language = {en} } @phdthesis{Krishnamoorthy2015, author = {Krishnamoorthy, Praveen}, title = {Regulatory roles of Ptdlns(4,5)P2 in trafficking of the cellulose synthase complex and identification of distinct plasma membrane localisation patterns of Arabidopsis PiP5-kinases}, school = {Universit{\"a}t Potsdam}, pages = {133}, year = {2015}, language = {en} } @phdthesis{HeidemannMalreddy2015, author = {Heidemann-Malreddy, Birte}, title = {Lost in a liminal space?}, school = {Universit{\"a}t Potsdam}, pages = {300}, year = {2015}, language = {en} } @phdthesis{Ogone2015, author = {Ogone, James Odhiambo}, title = {Domesticating modernity in Africa}, school = {Universit{\"a}t Potsdam}, pages = {229}, year = {2015}, language = {en} } @phdthesis{Tassler2015, author = {Taßler, Stephanie}, title = {Physical-Chemical Investigation of newly-synthesised Lysine-Based Amino-Functionalised Lipids for gene transfection in 2D and 3D model systems}, school = {Universit{\"a}t Potsdam}, pages = {142}, year = {2015}, language = {en} } @article{Kroener2015, author = {Kr{\"o}ner, Dominik}, title = {Laser-driven electron dynamics for circular dichroism in mass spectrometry}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, volume = {29}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, number = {17}, publisher = {The Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/C5CP02193F}, pages = {19643 -- 19655}, year = {2015}, abstract = {The distinction of enantiomers is a key aspect of chemical analysis. In mass spectrometry the distinction of enantiomers has been achieved by ionizing the sample with circularly polarized laser pulses and comparing the ion yields for light of opposite handedness. While resonant excitation conditions are expected to be most efficient, they are not required for the detection of a circular dichroism (CD) in the ion yield. However, the prediction of the size and sign of the circular dichroism becomes challenging if non-resonant multiphoton excitations are used to ionize the sample. Employing femtosecond laser pulses to drive electron wavepacket dynamics based on ab initio calculations, we attempt to reveal underlying mechanisms that determine the CD under non-resonant excitation conditions. Simulations were done for (R)-1,2-propylene oxide, using time-dependent configuration interaction singles with perturbative doubles (TD-CIS(D)) and the aug-cc-pVTZ basis set. Interactions between the electric field and the electric dipole and quadrupole as well as between the magnetic field and the magnetic dipole were explicitly accounted for. The ion yield was determined by treating states above the ionization potential as either stationary or non-stationary with energy-dependent lifetimes based on an approved heuristic approach. The observed population dynamics do not allow for a simple interpretation, because of highly non-linear interactions. Still, the various transition pathways are governed by resonant enantiospecific n-photon excitation, with preferably high transition dipole moments, which eventually dominate the CD in the ionized population.}, language = {en} } @article{LohrenBornhorstGallaetal.2015, author = {Lohren, Hanna and Bornhorst, Julia and Galla, Hans-Joachim and Schwerdtle, Tanja}, title = {The blood-cerebrospinal fluid barrier}, series = {Metallomics : integrated biometal science}, volume = {10}, journal = {Metallomics : integrated biometal science}, number = {7}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1756-5901}, doi = {10.1039/C5MT00171D}, pages = {1420 -- 1430}, year = {2015}, abstract = {Exposure to organic mercury compounds promotes primarily neurological effects. Although methylmercury is recognized as a potent neurotoxicant, its transfer into the central nervous system (CNS) is not fully evaluated. While methylmercury and thiomersal pass the blood-brain barrier, limited data are available regarding the second brain regulating interface, the blood-cerebrospinal fluid (CSF) barrier. This novel study was designed to investigate the effects of organic as well as inorganic mercury compounds on, and their transfer across, a porcine in vitro model of the blood-CSF barrier for the first time. The barrier system is significantly more sensitive towards organic Hg compounds as compared to inorganic compounds regarding the endpoints cytotoxicity and barrier integrity. Whereas there are low transfer rates from the blood side to the CSF side, our results strongly indicate an active transfer of the organic mercury compounds out of the CSF. These results are the first to demonstrate an efflux of organic mercury compounds regarding the CNS and provide a completely new approach in the understanding of mercury compounds specific transport.}, language = {en} } @article{MeyerRaberEbertetal.2015, author = {Meyer, S. and Raber, G. and Ebert, Franziska and Leffers, L. and M{\"u}ller, Sandra Marie and Taleshi, M. S. and Francesconi, Kevin A. and Schwerdtle, Tanja}, title = {In vitro toxicological characterisation of arsenic-containing fatty acids and three of their metabolites}, series = {Toxicology research}, volume = {5}, journal = {Toxicology research}, number = {4}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2045-4538}, doi = {10.1039/c5tx00122f}, pages = {1289 -- 1296}, year = {2015}, abstract = {Arsenic-containing fatty acids are a group of fat-soluble arsenic species (arsenolipids) which are present in marine fish and other seafood. Recently, it has been shown that arsenic-containing hydrocarbons, another group of arsenolipids, exert toxicity in similar concentrations comparable to arsenite although the toxic modes of action differ. Hence, a risk assessment of arsenolipids is urgently needed. In this study the cellular toxicity of a saturated (AsFA 362) and an unsaturated (AsFA 388) arsenic-containing fatty acid and three of their proposed metabolites (DMAV, DMAPr and thio-DMAPr) were investigated in human liver cells (HepG2). Even though both arsenic-containing fatty acids were less toxic as compared to arsenic-containing hydrocarbons and arsenite, significant effects were observable at μM concentrations. DMAV causes effects in a similar concentration range and it could be seen that it is metabolised to its highly toxic thio analogue thio-DMAV in HepG2 cells. Nevertheless, DMAPr and thio-DMAPr did not exert any cytotoxicity. In summary, our data indicate that risks to human health related to the presence of arsenic-containing fatty acids in marine food cannot be excluded. This stresses the need for a full in vitro and in vivo toxicological characterisation of these arsenolipids.}, language = {en} } @phdthesis{Pfestorf2015, author = {Pfestorf, Hans}, title = {Land use intensity and insect root herbivores}, school = {Universit{\"a}t Potsdam}, pages = {161}, year = {2015}, language = {en} } @phdthesis{Zupok2015, author = {Zupok, Arkadiusz}, title = {The psbB-operon is a major locus for plastome-genome incompatibility in Oenothera}, school = {Universit{\"a}t Potsdam}, pages = {108}, year = {2015}, language = {en} } @phdthesis{Hainich2015, author = {Hainich, Rainer}, title = {The Wolf-Rayet stars of the nitrogen sequence in environments of different metallicities}, school = {Universit{\"a}t Potsdam}, pages = {161}, year = {2015}, language = {en} } @article{KirchheckerTroegerMuellerBakeetal.2015, author = {Kirchhecker, Sarah and Tr{\"o}ger-M{\"u}ller, Steffen and Bake, Sebastian and Antonietti, Markus and Taubert, Andreas and Esposito, Davido}, title = {Renewable pyridinium ionic liquids from the continuous hydrothermal decarboxylation of furfural-amino acid derived pyridinium zwitterions}, series = {Green chemistry}, volume = {8}, journal = {Green chemistry}, number = {17}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9262}, doi = {10.1039/c5gc00913h}, pages = {4151 -- 4156}, year = {2015}, abstract = {Fully renewable pyridinium ionic liquids were synthesised via the hydrothermal decarboxylation of pyridinium zwitterions derived from furfural and amino acids in flow. The functionality of the resulting ionic liquid (IL) can be tuned by choice of different amino acids as well as different natural carboxylic acids as the counterions. A representative member of this new class of ionic liquids was successfully used for the synthesis of ionogels and as a solvent for the Heck coupling.}, language = {en} } @article{BartoloniJinMarcaidaetal.2015, author = {Bartoloni, Marco and Jin, Xian and Marcaida, Maria Jos{\´e} and Banha, Joao and Dibonaventura, Ivan and Bongoni, Swathi and Bartho, Kathrin and Gr{\"a}bner, Olivia and Sefkow, Michael and Darbre, Tamis and Reymond, Jean-Louis}, title = {Bridged bicyclic peptides as potential drug scaffolds}, series = {Chemical Science}, volume = {10}, journal = {Chemical Science}, number = {6}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2041-6520}, doi = {10.1039/C5SC01699A}, pages = {5473 -- 5490}, year = {2015}, abstract = {Double cyclization of short linear peptides obtained by solid phase peptide synthesis was used to prepare bridged bicyclic peptides (BBPs) corresponding to the topology of bridged bicyclic alkanes such as norbornane. Diastereomeric norbornapeptides were investigated by 1H-NMR, X-ray crystallography and CD spectroscopy and found to represent rigid globular scaffolds stabilized by intramolecular backbone hydrogen bonds with scaffold geometries determined by the chirality of amino acid residues and sharing structural features of β-turns and α-helices. Proteome profiling by capture compound mass spectrometry (CCMS) led to the discovery of the norbornapeptide 27c binding selectively to calmodulin as an example of a BBP protein binder. This and other BBPs showed high stability towards proteolytic degradation in serum.}, language = {en} } @article{SchulzeUtechtMoldtetal.2015, author = {Schulze, Michael and Utecht, Manuel Martin and Moldt, Thomas and Przyrembel, Daniel and Gahl, Cornelius and Weinelt, Martin and Saalfrank, Peter and Tegeder, Petra}, title = {Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, volume = {27}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, number = {17}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/c5cp03093e}, pages = {18079 -- 18086}, year = {2015}, abstract = {The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16\% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10-18 cm2 for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions.}, language = {en} } @article{GuhaWarsinkeTientcheuetal.2015, author = {Guha, S. and Warsinke, A. and Tientcheu, Ch. M. and Schmalz, K. and Meliani, C. and Wenger, Ch.}, title = {Label free sensing of creatinine using a 6 GHz CMOS near-field dielectric immunosensor}, series = {The analyst : the analytical journal of the Royal Society of Chemistry}, volume = {9}, journal = {The analyst : the analytical journal of the Royal Society of Chemistry}, number = {140}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {0003-2654}, doi = {10.1039/c4an02194k}, pages = {3019 -- 3027}, year = {2015}, abstract = {In this work we present a CMOS high frequency direct immunosensor operating at 6 GHz (C-band) for label free determination of creatinine. The sensor is fabricated in standard 0.13 μm SiGe:C BiCMOS process. The report also demonstrates the ability to immobilize creatinine molecules on a Si3N4 passivation layer of the standard BiCMOS/CMOS process, therefore, evading any further need of cumbersome post processing of the fabricated sensor chip. The sensor is based on capacitive detection of the amount of non-creatinine bound antibodies binding to an immobilized creatinine layer on the passivated sensor. The chip bound antibody amount in turn corresponds indirectly to the creatinine concentration used in the incubation phase. The determination of creatinine in the concentration range of 0.88-880 μM is successfully demonstrated in this work. A sensitivity of 35 MHz/10 fold increase in creatinine concentration (during incubation) at the centre frequency of 6 GHz is gained by the immunosensor. The results are compared with a standard optical measurement technique and the dynamic range and sensitivity is of the order of the established optical indication technique. The C-band immunosensor chip comprising an area of 0.3 mm2 reduces the sensing area considerably, therefore, requiring a sample volume as low as 2 μl. The small analyte sample volume and label free approach also reduce the experimental costs in addition to the low fabrication costs offered by the batch fabrication technique of CMOS/BiCMOS process.}, language = {en} } @article{NiedlBeta2015, author = {Niedl, Robert Raimund and Beta, Carsten}, title = {Hydrogel-driven paper-based microfluidics}, series = {LAB on a chip : miniaturisation for chemistry and biology}, volume = {11}, journal = {LAB on a chip : miniaturisation for chemistry and biology}, number = {15}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1473-0197}, doi = {10.1039/c5lc00276a}, pages = {2452 -- 2459}, year = {2015}, abstract = {Paper-based microfluidics provide an inexpensive, easy to use technology for point-of-care diagnostics in developing countries. Here, we combine paper-based microfluidic devices with responsive hydrogels to add an entire new class of functions to these versatile low-cost fluidic systems. The hydrogels serve as fluid reservoirs. In response to an external stimulus, e.g. an increase in temperature, the hydrogels collapse and release fluid into the structured paper substrate. In this way, chemicals that are either stored on the paper substrate or inside the hydrogel pads can be dissolved, premixed, and brought to reaction to fulfill specific analytic tasks. We demonstrate that multi-step sequences of chemical reactions can be implemented in a paper-based system and operated without the need for external precision pumps. We exemplify this technology by integrating an antibody-based E. coli test on a small and easy to use paper device.}, language = {en} } @article{NoechelReddyWangetal.2015, author = {N{\"o}chel, Ulrich and Reddy, Chaganti Srinivasa and Wang, Ke and Cui, Jing and Zizak, Ivo and Behl, Marc and Kratz, Karl and Lendlein, Andreas}, title = {Nanostructural changes in crystallizable controlling units determine the temperature-memory of polymers}, series = {Journal of Materials Chemistry A, Materials for energy and sustainability}, volume = {16}, journal = {Journal of Materials Chemistry A, Materials for energy and sustainability}, number = {3}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2050-7488}, doi = {10.1039/c4ta06586g}, pages = {8284 -- 8293}, year = {2015}, abstract = {Temperature-memory polymers remember the temperature, where they were deformed recently, enabled by broad thermal transitions. In this study, we explored a series of crosslinked poly[ethylene-co-(vinyl acetate)] networks (cPEVAs) comprising crystallizable polyethylene (PE) controlling units exhibiting a pronounced temperature-memory effect (TME) between 16 and 99 °C related to a broad melting transition (∼100 °C). The nanostructural changes in such cPEVAs during programming and activation of the TME were analyzed via in situ X-ray scattering and specific annealing experiments. Different contributions to the mechanism of memorizing high or low deformation temperatures (Tdeform) were observed in cPEVA, which can be associated to the average PE crystal sizes. At high deformation temperatures (>50 °C), newly formed PE crystals, which are established during cooling when fixing the temporary shape, dominated the TME mechanism. In contrast, at low Tdeform (<50 °C), corresponding to a cold drawing scenario, the deformation led preferably to a disruption of existing large crystals into smaller ones, which then fix the temporary shape upon cooling. The observed mechanism of memorizing a deformation temperature might enable the prediction of the TME behavior and the knowledge based design of other TMPs with crystallizable controlling units.}, language = {en} } @phdthesis{Primus2015, author = {Primus, Philipp-Alexander}, title = {High resolution spectroscopy as a tool to unravel structure-reactivity relationships in Eu3+ doped ceria/ceria-zirconia based catalyst nanomaterials}, school = {Universit{\"a}t Potsdam}, pages = {89}, year = {2015}, language = {en} } @phdthesis{Adamla2015, author = {Adamla, Frauke}, title = {Polyglutamine- and aging-dependent aberrancies in transcription and translation}, school = {Universit{\"a}t Potsdam}, pages = {109}, year = {2015}, language = {en} } @phdthesis{Tetzner2014, author = {Tetzner, Julia}, title = {Stability and change in academic, social, and emotional development from early adolescence to young adulthood}, school = {Universit{\"a}t Potsdam}, pages = {191}, year = {2014}, language = {en} } @phdthesis{Alseekh2015, author = {Alseekh, Saleh}, title = {Identification and mode of inheritance of quantitative trait loci (QTL) for metabolite abundance in tomato}, school = {Universit{\"a}t Potsdam}, pages = {134}, year = {2015}, language = {en} } @phdthesis{AlSaedy2015, author = {Al-Saedy, Ammar Jaffar Muhesin}, title = {Normally solvable lagrangian boundary value problems}, school = {Universit{\"a}t Potsdam}, pages = {110}, year = {2015}, language = {en} } @phdthesis{Yuan2015, author = {Yuan, Jiayin}, title = {Poly(Ionic Liquid)s}, school = {Universit{\"a}t Potsdam}, pages = {300}, year = {2015}, language = {en} } @phdthesis{Tian2014, author = {Tian, Fang}, title = {Vegetation and environmental changes on millennial, centennial and decadal time-scales in central Mongolia and their driving forces}, school = {Universit{\"a}t Potsdam}, pages = {139}, year = {2014}, language = {en} } @phdthesis{Sauter2015, author = {Sauter, Tilman}, title = {Function by structure}, school = {Universit{\"a}t Potsdam}, pages = {166}, year = {2015}, language = {en} } @phdthesis{Mengel2015, author = {Mengel, Matthias}, title = {Forcing Earth's sea level}, school = {Universit{\"a}t Potsdam}, pages = {173}, year = {2015}, language = {en} } @phdthesis{Mueller2014, author = {M{\"u}ller, J{\"o}rg}, title = {Response of bryophyte diversity to land-use and management in forest and grassland habitats}, school = {Universit{\"a}t Potsdam}, pages = {133}, year = {2014}, language = {en} } @phdthesis{Brem2014, author = {Brem, Patrick}, title = {Compact objects in dense astrophysical environments}, school = {Universit{\"a}t Potsdam}, pages = {173}, year = {2014}, language = {en} } @phdthesis{Soja2014, author = {Soja, Aleksandra Maria}, title = {Transcriptomic and metabolomic analysis of Arabidopsis thaliana during abiotic stress}, pages = {134}, year = {2014}, language = {en} } @phdthesis{Sklodowski2015, author = {Sklodowski, Kamil}, title = {Regulation of plant potassium channels}, school = {Universit{\"a}t Potsdam}, pages = {115}, year = {2015}, language = {en} } @phdthesis{Zhao2015, author = {Zhao, Liming}, title = {Characterization genes involved in leaf development and senescence of arabidopsis}, school = {Universit{\"a}t Potsdam}, pages = {137}, year = {2015}, language = {en} } @phdthesis{Eggers2014, author = {Eggers, Ute}, title = {Environmental impacts on white stork (Ciconia ciconia) breeding success}, school = {Universit{\"a}t Potsdam}, pages = {164}, year = {2014}, language = {en} } @phdthesis{Schoenebeck2014, author = {Sch{\"o}nebeck, Maria}, title = {Behavioural, visual, and electrophysiological correlates of infant reasoning about others' intentional actions}, school = {Universit{\"a}t Potsdam}, pages = {158}, year = {2014}, language = {en} } @phdthesis{Lang2014, author = {Lang, Iris Scarlett}, title = {Fetal programming of growth and metabolism by maternal dietary composition}, pages = {99}, year = {2014}, language = {en} } @article{MondalBehrensMatthesetal.2015, author = {Mondal, Suvendu Sekhar and Behrens, Karsten and Matthes, Philipp R. and Sch{\"o}nfeld, Fabian and Nitsch, J{\"o}rn and Steffen, Andreas and Primus, Philipp-Alexander and Kumke, Michael Uwe and M{\"u}ller-Buschbaum, Klaus and Holdt, Hans-J{\"u}rgen}, title = {White light emission of IFP-1 by in situ co-doping of the MOF pore system with Eu3+ and Tb3+}, series = {Journal of materials chemistry : C, Materials for optical and electronic devices}, volume = {18}, journal = {Journal of materials chemistry : C, Materials for optical and electronic devices}, number = {3}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2050-7534}, doi = {10.1039/C4TC02919D}, pages = {4623 -- 4631}, year = {2015}, abstract = {Co-doping of the MOF 3∞[Zn(2-methylimidazolate-4-amide-5-imidate)] (IFP-1 = Imidazolate Framework Potsdam-1) with luminescent Eu3+ and Tb3+ ions presents an approach to utilize the porosity of the MOF for the intercalation of luminescence centers and for tuning of the chromaticity to the emission of white light of the quality of a three color emitter. Organic based fluorescence processes of the MOF backbone as well as metal based luminescence of the dopants are combined to one homogenous single source emitter while retaining the MOF's porosity. The lanthanide ions Eu3+ and Tb3+ were doped in situ into IFP-1 upon formation of the MOF by intercalation into the micropores of the growing framework without a structure directing effect. Furthermore, the color point is temperature sensitive, so that a cold white light with a higher blue content is observed at 77 K and a warmer white light at room temperature (RT) due to the reduction of the organic emission at higher temperatures. The study further illustrates the dependence of the amount of luminescent ions on porosity and sorption properties of the MOF and proves the intercalation of luminescence centers into the pore system by low-temperature site selective photoluminescence spectroscopy, SEM and EDX. It also covers an investigation of the border of homogenous uptake within the MOF pores and the formation of secondary phases of lanthanide formates on the surface of the MOF. Crossing the border from a homogenous co-doping to a two-phase composite system can be beneficially used to adjust the character and warmth of the white light. This study also describes two-color emitters of the formula Ln@IFP-1a-d (Ln: Eu, Tb) by doping with just one lanthanide Eu3+ or Tb3+.}, language = {en} } @article{MegowRoehrSchmidtamBuschetal.2015, author = {Megow, J{\"o}rg and R{\"o}hr, Merle I. S. and Schmidt am Busch, Marcel and Renger, Thomas and Mitrić, Roland and Kirstein, Stefan and Rabe, J{\"u}rgen P. and May, Volkhard}, title = {Site-dependence of van der Waals interaction explains exciton spectra of double-walled tubular J-aggregates}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies}, volume = {17}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies}, number = {10}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9084}, doi = {10.1039/c4cp05945j}, pages = {6741 -- 6747}, year = {2015}, abstract = {The simulation of the optical properties of supramolecular aggregates requires the development of methods, which are able to treat a large number of coupled chromophores interacting with the environment. Since it is currently not possible to treat large systems by quantum chemistry, the Frenkel exciton model is a valuable alternative. In this work we show how the Frenkel exciton model can be extended in order to explain the excitonic spectra of a specific double-walled tubular dye aggregate explicitly taking into account dispersive energy shifts of ground and excited states due to van der Waals interaction with all surrounding molecules. The experimentally observed splitting is well explained by the site-dependent energy shift of molecules placed at the inner or outer side of the double-walled tube, respectively. Therefore we can conclude that inclusion of the site-dependent dispersive effect in the theoretical description of optical properties of nanoscaled dye aggregates is mandatory.}, language = {en} } @article{CroneAschnerSchwerdtleetal.2015, author = {Crone, Barbara and Aschner, Michael A. and Schwerdtle, Tanja and Karst, Uwe and Bornhorst, Julia}, title = {Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS}, series = {Metallomics}, volume = {2015}, journal = {Metallomics}, number = {7}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1756-591X}, doi = {10.1039/c5mt00096c}, pages = {1189 -- 1195}, year = {2015}, abstract = {cis-Diamminedichloroplatinum(II) (Cisplatin) is one of the most important and frequently used cytostatic drugs for the treatment of various solid tumors. Herein, a laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) method incorporating a fast and simple sample preparation protocol was developed for the elemental mapping of Cisplatin in the model organism Caenorhabditis elegans (C. elegans). The method allows imaging of the spatially-resolved elemental distribution of platinum in the whole organism with respect to the anatomic structure in L4 stage worms at a lateral resolution of 5 μm. In addition, a dose- and time-dependent Cisplatin uptake was corroborated quantitatively by a total reflection X-ray fluorescence spectroscopy (TXRF) method, and the elemental mapping indicated that Cisplatin is located in the intestine and in the head of the worms. Better understanding of the distribution of Cisplatin in this well-established model organism will be instrumental in deciphering Cisplatin toxicity and pharmacokinetics. Since the cytostatic effect of Cisplatin is based on binding the DNA by forming intra- and interstrand crosslinks, the response of poly(ADP-ribose)metabolism enzyme 1 (pme-1) deletion mutants to Cisplatin was also examined. Loss of pme-1, which is the C. elegans ortholog of human poly(ADP-ribose) polymerase 1 (PARP-1) led to disturbed DNA damage response. With respect to survival and brood size, pme-1 deletion mutants were more sensitive to Cisplatin as compared to wildtype worms, while Cisplatin uptake was indistinguishable.}, language = {en} } @phdthesis{Beinrucker2015, author = {Beinrucker, Andre}, title = {Variable selection in high dimensional data analysis with applications}, school = {Universit{\"a}t Potsdam}, pages = {VII, 107}, year = {2015}, language = {en} } @article{PietraLangGrebe2015, author = {Pietra, Stefano and Lang, Patricia and Grebe, Markus}, title = {SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana}, series = {Physiologia Plantarum}, volume = {153}, journal = {Physiologia Plantarum}, number = {3}, doi = {DOI: 10.1111/ppl.12257}, pages = {440 -- 453}, year = {2015}, abstract = {Patterned differentiation of distinct cell types is essential for the development of multicellular organisms. The root epidermis of Arabidopsis thaliana is composed of alternating files of root hair and non-hair cells and represents a model system for studying the control of cell-fate acquisition. Epidermal cell fate is regulated by a network of genes that translate positional information from the underlying cortical cell layer into a specific pattern of differentiated cells. While much is known about the genes of this network, new players continue to be discovered. Here we show that the SABRE (SAB) gene, known to mediate microtubule organization, anisotropic cell growth and planar polarity, has an effect on root epidermal hair cell patterning. Loss of SAB function results in ectopic root hair formation and destabilizes the expression of cell fate and differentiation markers in the root epidermis, including expression of the WEREWOLF (WER) and GLABRA2 (GL2) genes. Double mutant analysis reveal that wer and caprice (cpc) mutants, defective in core components of the epidermal patterning pathway, genetically interact with sab. This suggests that SAB may act on epidermal patterning upstream of WER and CPC. Hence, we provide evidence for a role of SAB in root epidermal patterning by affecting cell-fate stabilization. Our work opens the door for future studies addressing SAB-dependent functions of the cytoskeleton during root epidermal patterning.}, language = {en} } @article{KieferClaesNzayisengaetal.2015, author = {Kiefer, Christian S. and Claes, Andrea R. and Nzayisenga, Jean-Claude and Pietra, Stefano and Stanislas, Thomas and Ikeda, Yoshihisa and Grebe, Markus}, title = {Arabidopsis AIP1-2 restricted by WER-mediated patterning modulates planar polarity}, series = {Development}, journal = {Development}, number = {142}, doi = {doi: 10.1242/dev.111013}, pages = {151 -- 161}, year = {2015}, abstract = {The coordination of cell polarity within the plane of the tissue layer (planar polarity) is crucial for the development of diverse multicellular organisms. Small Rac/Rho-family GTPases and the actin cytoskeleton contribute to planar polarity formation at sites of polarity establishment in animals and plants. Yet, upstream pathways coordinating planar polarity differ strikingly between kingdoms. In the root of Arabidopsis thaliana, a concentration gradient of the phytohormone auxin coordinates polar recruitment of Rho-of-plant (ROP) to sites of polar epidermal hair initiation. However, little is known about cytoskeletal components and interactions that contribute to this planar polarity or about their relation to the patterning machinery. Here, we show that ACTIN7 (ACT7) represents a main actin isoform required for planar polarity of root hair positioning, interacting with the negative modulator ACTIN-INTERACTING PROTEIN1-2 (AIP1-2). ACT7, AIP1-2 and their genetic interaction are required for coordinated planar polarity of ROP downstream of ethylene signalling. Strikingly, AIP1-2 displays hair cell file-enriched expression, restricted by WEREWOLF (WER)-dependent patterning and modified by ethylene and auxin action. Hence, our findings reveal AIP1-2, expressed under control of the WER-dependent patterning machinery and the ethylene signalling pathway, as a modulator of actin-mediated planar polarity.}, language = {en} } @article{MetzlerBauerRasmussenetal.2015, author = {Metzler, Ralf and Bauer, Maximilian and Rasmussen, Emil S. and Lomholt, Michael A.}, title = {Real sequence effects on the search dynamics of transcription factors on DNA}, series = {Scientific Reports}, volume = {5}, journal = {Scientific Reports}, number = {10072}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep10072}, year = {2015}, abstract = {Recent experiments show that transcription factors (TFs) indeed use the facilitated diffusion mechanism to locate their target sequences on DNA in living bacteria cells: TFs alternate between sliding motion along DNA and relocation events through the cytoplasm. From simulations and theoretical analysis we study the TF-sliding motion for a large section of the DNA-sequence of a common E. coli strain, based on the two-state TF-model with a fast-sliding search state and a recognition state enabling target detection. For the probability to detect the target before dissociating from DNA the TF-search times self-consistently depend heavily on whether or not an auxiliary operator (an accessible sequence similar to the main operator) is present in the genome section. Importantly, within our model the extent to which the interconversion rates between search and recognition states depend on the underlying nucleotide sequence is varied. A moderate dependence maximises the capability to distinguish between the main operator and similar sequences. Moreover, these auxiliary operators serve as starting points for DNA looping with the main operator, yielding a spectrum of target detection times spanning several orders of magnitude. Auxiliary operators are shown to act as funnels facilitating target detection by TFs.}, language = {en} } @phdthesis{Gassmoeller2014, author = {Gaßm{\"o}ller, Ren{\´e}}, title = {The interaction of subducted slabs and plume generation zones in geodynamic models}, school = {Universit{\"a}t Potsdam}, pages = {158}, year = {2014}, language = {en} } @article{HaendlerKlieglAdani2015, author = {Haendler, Yair and Kliegl, Reinhold and Adani, Flavia}, title = {Discourse accessibility constraints in children´s processing of object relative clauses}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {860}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00860}, year = {2015}, abstract = {Children's poor performance on object relative clauses has been explained in terms of intervention locality. This approach predicts that object relatives with a full DP head and an embedded pronominal subject are easier than object relatives in which both the head noun and the embedded subject are full DPs. This prediction is shared by other accounts formulated to explain processing mechanisms. We conducted a visual-world study designed to test the off-line comprehension and on-line processing of object relatives in German-speaking 5-year-olds. Children were tested on three types of object relatives, all having a full DP head noun and differing with respect to the type of nominal phrase that appeared in the embedded subject position: another full DP, a 1st- or a 3rd-person pronoun. Grammatical skills and memory capacity were also assessed in order to see whether and how they affect children's performance. Most accurately processed were object relatives with 1st-person pronoun, independently of children's language and memory skills. Performance on object relatives with two full DPs was overall more accurate than on object relatives with 3rd-person pronoun. In the former condition, children with stronger grammatical skills accurately processed the structure and their memory abilities determined how fast they were; in the latter condition, children only processed accurately the structure if they were strong both in their grammatical skills and in their memory capacity. The results are discussed in the light of accounts that predict different pronoun effects like the ones we find, which depend on the referential properties of the pronouns. We then discuss which role language and memory abilities might have in processing object relatives with various embedded nominal phrases.}, language = {en} } @article{HaeusslerBader2015, author = {H{\"a}ussler, Jana and Bader, Markus}, title = {An interference account of the missing-VP effect}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {766}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00766}, year = {2015}, abstract = {Sentences with doubly center-embedded relative clauses in which a verb phrase (VP) is missing are sometimes perceived as grammatical, thus giving rise to an illusion of grammaticality. In this paper, we provide a new account of why missing-VP sentences, which are both complex and ungrammatical, lead to an illusion of grammaticality, the so-called missing-VP effect. We propose that the missing-VP effect in particular, and processing difficulties with multiply center-embedded clauses more generally, are best understood as resulting from interference during cue-based retrieval. When processing a sentence with double center-embedding, a retrieval error due to interference can cause the verb of an embedded clause to be erroneously attached into a higher clause. This can lead to an illusion of grammaticality in the case of missing-VP sentences and to processing complexity in the case of complete sentences with double center-embedding. Evidence for an interference account of the missing-VP effect comes from experiments that have investigated the missing-VP effect in German using a speeded grammaticality judgments procedure. We review this evidence and then present two new experiments that show that the missing-VP effect can be found in German also with less restricting procedures. One experiment was a questionnaire study which required grammaticality judgments from participants without imposing any time constraints. The second experiment used a self-paced reading procedure and did not require any judgments. Both experiments confirm the prior findings of missing-VP effects in German and also show that the missing-VP effect is subject to a primacy effect as known from the memory literature. Based on this evidence, we argue that an account of missing-VP effects in terms of interference during cue-based retrieval is superior to accounts in terms of limited memory resources or in terms of experience with embedded structures.}, language = {en} } @article{FelserPattersonCunnings2015, author = {Felser, Claudia and Patterson, Clare and Cunnings, Ian}, title = {Structural constraints on pronoun binding and coreference: Evidence from eye movements during reading}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {840}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00840}, year = {2015}, abstract = {A number of recent studies have investigated how syntactic and non-syntactic constraints combine to cue memory retrieval during anaphora resolution. In this paper we investigate how syntactic constraints and gender congruence interact to guide memory retrieval during the resolution of subject pronouns. Subject pronouns are always technically ambiguous, and the application of syntactic constraints on their interpretation depends on properties of the antecedent that is to be retrieved. While pronouns can freely corefer with non-quantified referential antecedents, linking a pronoun to a quantified antecedent is only possible in certain syntactic configurations via variable binding. We report the results from a judgment task and three online reading comprehension experiments investigating pronoun resolution with quantified and non-quantified antecedents. Results from both the judgment task and participants' eye movements during reading indicate that comprehenders freely allow pronouns to corefer with non-quantified antecedents, but that retrieval of quantified antecedents is restricted to specific syntactic environments. We interpret our findings as indicating that syntactic constraints constitute highly weighted cues to memory retrieval during anaphora resolution.}, language = {en} } @article{MetzlerCherstvyChechkinetal.2015, author = {Metzler, Ralf and Cherstvy, Andrey G. and Chechkin, Aleksei V. and Bodrova, Anna S.}, title = {Ultraslow scaled Brownian motion}, series = {New journal of physics : the open-access journal for physics}, volume = {17}, journal = {New journal of physics : the open-access journal for physics}, number = {063038}, publisher = {Dt. Physikalische Ges., IOP}, address = {Bad Honnef, London}, issn = {1367-2630}, doi = {10.1088/1367-2630/17/6/063038}, year = {2015}, abstract = {We define and study in detail utraslow scaled Brownian motion (USBM) characterized by a time dependent diffusion coefficient of the form . For unconfined motion the mean squared displacement (MSD) of USBM exhibits an ultraslow, logarithmic growth as function of time, in contrast to the conventional scaled Brownian motion. In a harmonic potential the MSD of USBM does not saturate but asymptotically decays inverse-proportionally to time, reflecting the highly non-stationary character of the process. We show that the process is weakly non-ergodic in the sense that the time averaged MSD does not converge to the regular MSD even at long times, and for unconfined motion combines a linear lag time dependence with a logarithmic term. The weakly non-ergodic behaviour is quantified in terms of the ergodicity breaking parameter. The USBM process is also shown to be ageing: observables of the system depend on the time gap between initiation of the test particle and start of the measurement of its motion. Our analytical results are shown to agree excellently with extensive computer simulations.}, language = {en} } @phdthesis{Mueller2015, author = {M{\"u}ller, Eva Nora}, title = {The ecohydrological transfers, interactions and degradation arising from high-intensity storm events}, school = {Universit{\"a}t Potsdam}, pages = {224}, year = {2015}, language = {en} } @phdthesis{Pinchasik2015, author = {Pinchasik, Bat-El Shani}, title = {Manipulaton of Microbubbles Inspired by Bubble Use in Nature}, school = {Universit{\"a}t Potsdam}, pages = {123}, year = {2015}, language = {en} } @phdthesis{Zhou2014, author = {Zhou, Xu}, title = {Atmospheric interactions with land surface in the arctic based on regional climate model solutions}, pages = {143}, year = {2014}, language = {en} } @phdthesis{HoffmannRobbiani2015, author = {Hoffmann Robbiani, Sandra}, title = {But 7 is yellower than Q, isn't it?}, publisher = {Hoffmann}, address = {Darmstadt}, isbn = {978-3-946069-01-0}, pages = {393}, year = {2015}, language = {en} } @phdthesis{Prill2015, author = {Prill, Sebastian}, title = {Real-Time in vitro toxicity monotoring in a microfluidic bioreactor for drug and chemical safety assessment}, pages = {119}, year = {2015}, language = {en} } @phdthesis{Kamprath2014, author = {Kamprath, Martin}, title = {A microfoundations perspectives on fresight and business models}, pages = {224}, year = {2014}, language = {en} } @phdthesis{Kocyan2014, author = {Kocyan, Alexander}, title = {Evolution within the speciose plant group of asparagales}, year = {2014}, language = {en} } @phdthesis{Gericke2014, author = {Gericke, Lutz}, title = {Tele-Board - Supporting and analyzing creative collaboration in synchronous and asynchronous scenario}, pages = {186}, year = {2014}, language = {en} } @article{LamprechtMargaria2015, author = {Lamprecht, Anna-Lena and Margaria, Tiziana}, title = {Scientific workflows and XMDD}, series = {Process design for natural scientists}, journal = {Process design for natural scientists}, editor = {Lamprecht, Anna-Lena and Margaria, Tiziana}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45006-2}, pages = {1 -- 13}, year = {2015}, language = {en} } @article{Blaese2014, author = {Blaese, Leif}, title = {Data mining for unidentified protein squences}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {73 -- 87}, year = {2014}, abstract = {Through the use of next generation sequencing (NGS) technology, a lot of newly sequenced organisms are now available. Annotating those genes is one of the most challenging tasks in sequence biology. Here, we present an automated workflow to find homologue proteins, annotate sequences according to function and create a three-dimensional model.}, language = {en} } @article{Schuett2014, author = {Sch{\"u}tt, Christine}, title = {Identification of differentially expressed genes}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {127 -- 139}, year = {2014}, abstract = {With the jABC it is possible to realize workflows for numerous questions in different fields. The goal of this project was to create a workflow for the identification of differentially expressed genes. This is of special interest in biology, for it gives the opportunity to get a better insight in cellular changes due to exogenous stress, diseases and so on. With the knowledge that can be derived from the differentially expressed genes in diseased tissues, it becomes possible to find new targets for treatment.}, language = {en} } @article{Kuntzsch2014, author = {Kuntzsch, Christian}, title = {Visualization of data transfer paths}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {140 -- 148}, year = {2014}, abstract = {A workflow for visualizing server connections using the Google Maps API was built in the jABC. It makes use of three basic services: An XML-based IP address geolocation web service, a command line tool and the Static Maps API. The result of the workflow is an URL leading to an image file of a map, showing server connections between a client and a target host.}, language = {en} } @article{Teske2014, author = {Teske, Daniel}, title = {Geocoder accuracy ranking}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {161 -- 174}, year = {2014}, abstract = {Finding an address on a map is sometimes tricky: the chosen map application may be unfamiliar with the enclosed region. There are several geocoders on the market, they have different databases and algorithms to compute the query. Consequently, the geocoding results differ in their quality. Fortunately the geocoders provide a rich set of metadata. The workflow described in this paper compares this metadata with the aim to find out which geocoder is offering the best-fitting coordinate for a given address.}, language = {en} } @article{Schulze2014, author = {Schulze, Gunnar}, title = {Workflow for rapid metagenome analysis}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {88 -- 100}, year = {2014}, abstract = {Analyses of metagenomes in life sciences present new opportunities as well as challenges to the scientific community and call for advanced computational methods and workflows. The large amount of data collected from samples via next-generation sequencing (NGS) technologies render manual approaches to sequence comparison and annotation unsuitable. Rather, fast and efficient computational pipelines are needed to provide comprehensive statistics and summaries and enable the researcher to choose appropriate tools for more specific analyses. The workflow presented here builds upon previous pipelines designed for automated clustering and annotation of raw sequence reads obtained from next-generation sequencing technologies such as 454 and Illumina. Employing specialized algorithms, the sequence reads are processed at three different levels. First, raw reads are clustered at high similarity cutoff to yield clusters which can be exported as multifasta files for further analyses. Independently, open reading frames (ORFs) are predicted from raw reads and clustered at two strictness levels to yield sets of non-redundant sequences and ORF families. Furthermore, single ORFs are annotated by performing searches against the Pfam database}, language = {en} } @phdthesis{Stutz2014, author = {Stutz, Franziska}, title = {Reading motivation, reading amount, and reading comprehension in the early elementary years}, pages = {212}, year = {2014}, language = {en} } @phdthesis{Pagel2014, author = {Pagel, J{\"o}rn}, title = {Statistical process-based models for the understanding and prediction of range dynamics}, pages = {VII, 147}, year = {2014}, language = {en} } @book{OPUS4-7534, title = {Process design for natural scientists}, series = {Communications in computer and information science ; 500}, journal = {Communications in computer and information science ; 500}, editor = {Lambrecht, Anna-Lena and Margaria, Tizian}, publisher = {Springer}, address = {Wiesbaden}, isbn = {978-3-662-45005-5}, pages = {X, 251}, year = {2014}, abstract = {This book presents an agile and model-driven approach to manage scientific workflows. The approach is based on the Extreme Model Driven Design (XMDD) paradigm and aims at simplifying and automating the complex data analysis processes carried out by scientists in their day-to-day work. Besides documenting the impact the workflow modeling might have on the work of natural scientists, this book serves three major purposes: 1. It acts as a primer for practitioners who are interested to learn how to think in terms of services and workflows when facing domain-specific scientific processes. 2. It provides interesting material for readers already familiar with this kind of tools, because it introduces systematically both the technologies used in each case study and the basic concepts behind them. 3. As the addressed thematic field becomes increasingly relevant for lectures in both computer science and experimental sciences, it also provides helpful material for teachers that plan similar courses.}, language = {en} } @article{Sens2014, author = {Sens, Henriette}, title = {Web-Based map generalization tools put to the test: a jABC workflow}, series = {Process Design for Natural Scientists: an agile model-driven approach}, journal = {Process Design for Natural Scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {175 -- 185}, year = {2014}, abstract = {Geometric generalization is a fundamental concept in the digital mapping process. An increasing amount of spatial data is provided on the web as well as a range of tools to process it. This jABC workflow is used for the automatic testing of web-based generalization services like mapshaper.org by executing its functionality, overlaying both datasets before and after the transformation and displaying them visually in a .tif file. Mostly Web Services and command line tools are used to build an environment where ESRI shapefiles can be uploaded, processed through a chosen generalization service and finally visualized in Irfanview.}, language = {en} } @article{Noack2014, author = {Noack, Franziska}, title = {CREADED: Colored-Relief application for digital elevation data}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {186 -- 199}, year = {2014}, abstract = {In the geoinformatics field, remote sensing data is often used for analyzing the characteristics of the current investigation area. This includes DEMs, which are simple raster grids containing grey scales representing the respective elevation values. The project CREADED that is presented in this paper aims at making these monochrome raster images more significant and more intuitively interpretable. For this purpose, an executable interactive model for creating a colored and relief-shaded Digital Elevation Model (DEM) has been designed using the jABC framework. The process is based on standard jABC-SIBs and SIBs that provide specific GIS functions, which are available as Web services, command line tools and scripts.}, language = {en} } @article{Respondek2014, author = {Respondek, Tobias}, title = {A workflow for computing potential areas for wind turbines}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, pages = {200 -- 215}, year = {2014}, abstract = {This paper describes the implementation of a workflow model for service-oriented computing of potential areas for wind turbines in jABC. By implementing a re-executable model the manual effort of a multi-criteria site analysis can be reduced. The aim is to determine the shift of typical geoprocessing tools of geographic information systems (GIS) from the desktop to the web. The analysis is based on a vector data set and mainly uses web services of the "Center for Spatial Information Science and Systems" (CSISS). This paper discusses effort, benefits and problems associated with the use of the web services.}, language = {en} } @article{Scheele2014, author = {Scheele, Lasse}, title = {Location analysis for placing artificial reefs}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {216 -- 228}, year = {2014}, abstract = {Location analyses are among the most common tasks while working with spatial data and geographic information systems. Automating the most frequently used procedures is therefore an important aspect of improving their usability. In this context, this project aims to design and implement a workflow, providing some basic tools for a location analysis. For the implementation with jABC, the workflow was applied to the problem of finding a suitable location for placing an artificial reef. For this analysis three parameters (bathymetry, slope and grain size of the ground material) were taken into account, processed, and visualized with the The Generic Mapping Tools (GMT), which were integrated into the workflow as jETI-SIBs. The implemented workflow thereby showed that the approach to combine jABC with GMT resulted in an user-centric yet user-friendly tool with high-quality cartographic outputs.}, language = {en} } @article{Kind2014, author = {Kind, Josephine}, title = {Creation of topographic maps}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, pages = {229 -- 238}, year = {2014}, abstract = {Location analyses are among the most common tasks while working with spatial data and geographic information systems. Automating the most frequently used procedures is therefore an important aspect of improving their usability. In this context, this project aims to design and implement a workflow, providing some basic tools for a location analysis. For the implementation with jABC, the workflow was applied to the problem of finding a suitable location for placing an artificial reef. For this analysis three parameters (bathymetry, slope and grain size of the ground material) were taken into account, processed, and visualized with the The Generic Mapping Tools (GMT), which were integrated into the workflow as jETI-SIBs. The implemented workflow thereby showed that the approach to combine jABC with GMT resulted in an user-centric yet user-friendly tool with high-quality cartographic outputs.}, language = {en} } @article{Holler2014, author = {Holler, Robin}, title = {GraffDok - a graffiti documentation application}, series = {Process design for natural scientists: an agile model-driven approach}, journal = {Process design for natural scientists: an agile model-driven approach}, number = {500}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-45005-5}, issn = {1865-0929}, pages = {239 -- 251}, year = {2014}, abstract = {GraffDok is an application helping to maintain an overview over sprayed images somewhere in a city. At the time of writing it aims at vandalism rather than at beautiful photographic graffiti in an underpass. Looking at hundreds of tags and scribbles on monuments, house walls, etc. it would be interesting to not only record them in writing but even make them accessible electronically, including images. GraffDok's workflow is simple and only requires an EXIF-GPS-tagged photograph of a graffito. It automatically determines its location by using reverse geocoding with the given GPS-coordinates and the Gisgraphy WebService. While asking the user for some more meta data, GraffDok analyses the image in parallel with this and tries to detect fore- and background - before extracting the drawing lines and make them stand alone. The command line based tool ImageMagick is used here as well as for accessing EXIF data. Any meta data is written to csv-files, which will stay easily accessible and can be integrated in TeX-files as well. The latter ones are converted to PDF at the end of the workflow, containing a table about all graffiti and a summary for each - including the generated characteristic graffiti pattern image.}, language = {en} } @book{ThompsonFoxCouperKuhlen2015, author = {Thompson, Sandra A. and Fox, Barbara A. and Couper-Kuhlen, Elizabeth}, title = {Grammar in everyday talk}, series = {Studies in interactional sociolinguistics ; 31}, journal = {Studies in interactional sociolinguistics ; 31}, publisher = {Cambridge Univ. Press}, address = {Cambridge}, isbn = {978-1-107-03102-9}, publisher = {Universit{\"a}t Potsdam}, pages = {XIV, 341}, year = {2015}, abstract = {This book surveys how English speakers use grammar to formulate responses in ordinary conversation. The authors show that speakers build their responses in a variety of ways: the responses can be longer or shorter, repetitive or not, and can be uttered with different intonational 'melodies'"-- "Drawing on everyday telephone and video interactions, this book surveys how English speakers use grammar to formulate responses in ordinary conversation. The authors show that speakers build their responses in a variety of ways: the responses can be longer or shorter, repetitive or not, and can be uttered with different intonational 'melodies'. Focusing on four sequence types: responses to questions ('What time are we leaving?' - 'Seven'), responses to informings ('The May Company are sure having a big sale' - 'Are they?'), responses to assessments ('Track walking is so boring. Even with headphones' - 'It is'), and responses to requests ('Please don't tell Adeline' - 'Oh no I won't say anything'), they argue that an interactional approach holds the key to explaining why some types of utterances in English conversation seem to have something 'missing' and others seem overly wordy.}, language = {en} } @article{JaegerEngelmannVasishth2015, author = {J{\"a}ger, Lena Ann and Engelmann, Felix and Vasishth, Shravan}, title = {Retrieval interference in reflexive processing}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {617}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00617}, year = {2015}, abstract = {We conducted two eye-tracking experiments investigating the processing of the Mandarin reflexive ziji in order to tease apart structurally constrained accounts from standard cue-based accounts of memory retrieval. In both experiments, we tested whether structurally inaccessible distractors that fulfill the animacy requirement of ziji influence processing times at the reflexive. In Experiment 1, we manipulated animacy of the antecedent and a structurally inaccessible distractor intervening between the antecedent and the reflexive. In conditions where the accessible antecedent mismatched the animacy cue, we found inhibitory interference whereas in antecedent-match conditions, no effect of the distractor was observed. In Experiment 2, we tested only antecedent-match configurations and manipulated locality of the reflexive-antecedent binding (Mandarin allows non-local binding). Participants were asked to hold three distractors (animate vs. inanimate nouns) in memory while reading the target sentence. We found slower reading times when animate distractors were held in memory (inhibitory interference). Moreover, we replicated the locality effect reported in previous studies. These results are incompatible with structure-based accounts. However, the cue-based ACT-R model of Lewis and Vasishth (2005) cannot explain the observed pattern either. We therefore extend the original ACT-R model and show how this model not only explains the data presented in this article, but is also able to account for previously unexplained patterns in the literature on reflexive processing.}, language = {en} } @article{JaegerBenzRoeseretal.2015, author = {J{\"a}ger, Lena Ann and Benz, Lena and Roeser, Jens and Dillon, Brian W. and Vasishth, Shravan}, title = {Teasing apart retrieval and encoding interference in the processing of anaphors}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {506}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00506}, year = {2015}, abstract = {Two classes of account have been proposed to explain the memory processes subserving the processing of reflexive-antecedent dependencies. Structure-based accounts assume that the retrieval of the antecedent is guided by syntactic tree-configurational information without considering other kinds of information such as gender marking in the case of English reflexives. By contrast, unconstrained cue-based retrieval assumes that all available information is used for retrieving the antecedent. Similarity-based interference effects from structurally illicit distractors which match a non-structural retrieval cue have been interpreted as evidence favoring the unconstrained cue-based retrieval account since cue-based retrieval interference from structurally illicit distractors is incompatible with the structure-based account. However, it has been argued that the observed effects do not necessarily reflect interference occurring at the moment of retrieval but might equally well be accounted for by interference occurring already at the stage of encoding or maintaining the antecedent in memory, in which case they cannot be taken as evidence against the structure-based account. We present three experiments (self-paced reading and eye-tracking) on German reflexives and Swedish reflexive and pronominal possessives in which we pit the predictions of encoding interference and cue-based retrieval interference against each other. We could not find any indication that encoding interference affects the processing ease of the reflexive-antecedent dependency formation. Thus, there is no evidence that encoding interference might be the explanation for the interference effects observed in previous work. We therefore conclude that invoking encoding interference may not be a plausible way to reconcile interference effects with a structure-based account of reflexive processing.}, language = {en} } @article{GoychukGoychuk2015, author = {Goychuk, Igor and Goychuk, Andriy}, title = {Stochastic Wilson}, series = {New journal of physics}, volume = {17}, journal = {New journal of physics}, number = {4}, publisher = {Deutsche Physikalische Gesellschaft, Institute of Physics}, address = {Bad Honnef, London}, issn = {1367-2630}, doi = {10.1088/1367-2630/17/4/045029}, year = {2015}, abstract = {We consider a simple Markovian class of the stochastic Wilson-Cowan type models of neuronal network dynamics, which incorporates stochastic delay caused by the existence of a refractory period of neurons. From the point of view of the dynamics of the individual elements, we are dealing with a network of non-Markovian stochastic two-state oscillators with memory, which are coupled globally in a mean-field fashion. This interrelation of a higher-dimensional Markovian and lower-dimensional non-Markovian dynamics is discussed in its relevance to the general problem of the network dynamics of complex elements possessing memory. The simplest model of this class is provided by a three-state Markovian neuron with one refractory state, which causes firing delay with an exponentially decaying memory within the two-state reduced model. This basic model is used to study critical avalanche dynamics (the noise sustained criticality) in a balanced feedforward network consisting of the excitatory and inhibitory neurons. Such avalanches emerge due to the network size dependent noise (mesoscopic noise). Numerical simulations reveal an intermediate power law in the distribution of avalanche sizes with the critical exponent around -1.16. We show that this power law is robust upon a variation of the refractory time over several orders of magnitude. However, the avalanche time distribution is biexponential. It does not reflect any genuine power law dependence.}, language = {en} } @article{WiebkingNorthoff2015, author = {Wiebking, Christine and Northoff, Georg}, title = {Neural activity during interoceptive awareness and its associations with alexithymia}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {589}, publisher = {Frontiers Research Foundation}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00589}, year = {2015}, abstract = {Objective: Alexithymia relates to difficulties recognizing and describing emotions. It has been linked to subjectively increased interoceptive awareness (IA) and to psychiatric illnesses such as major depressive disorder (MDD) and somatization. MDD in turn is characterized by aberrant emotion processing and IA on the subjective as well as on the neural level. However, a link between neural activity in response to IA and alexithymic traits in health and depression remains unclear. Methods: A well-established fMRI task was used to investigate neural activity during IA (heartbeat counting) and exteroceptive awareness (tone counting) in non-psychiatric controls (NC) and MDD. Firstly, comparing MDD and NC, a linear relationship between IA-related activity and scores of the Toronto Alexithymia Scale (TAS) was investigated through whole-brain regression. Secondly, NC were divided by median-split of TAS scores into groups showing low (NC-low) or high (NC-high) alexithymia. MDD and NC-high showed equally high TAS scores. Subsequently, IA-related neural activity was compared on a whole-brain level between the three independent samples (MDD, NC-low, NC-high). Results: Whole-brain regressions between MDD and NC revealed neural differences during IA as a function of TAS-DD (subscale difficulty describing feelings) in the supragenual anterior cingulate cortex (sACC; BA 24/32), which were due to negative associations between TAS-DD and IA-related activity in NC. Contrasting NC subgroups after median-split on a whole-brain level, high TAS scores were associated with decreased neural activity during IA in the sACC and increased insula activity. Though having equally high alexithymia scores, NC-high showed increased insula activity during IA compared to MDD, whilst both groups showed decreased activity in the sACC. Conclusions: Within the context of decreased sACC activity during IA in alexithymia (NC-high and MDD), increased insula activity might mirror a compensatory mechanism in NC-high, which is disrupted in MDD.}, language = {en} } @phdthesis{Sprenger2014, author = {Sprenger, Heike}, title = {Characterization of drought tolerance in potato cultivars for identification of molecular markers}, pages = {146}, year = {2014}, language = {en} } @phdthesis{Ippen2014, author = {Ippen, Christian Justus}, title = {Indium phosphide and zinc selenide quantum dots for light-emitting devices}, pages = {vii, 153}, year = {2014}, language = {en} } @phdthesis{Geckin2015, author = {Geckin, Vasfiye}, title = {The interpretation of logical connections by monolingual and bilingual children}, pages = {ix, 181}, year = {2015}, language = {en} } @phdthesis{Omidbakhshfard2014, author = {Omidbakhshfard, Mohammad Amin}, title = {Functional analysis of the role of GRF9 in leaf development and establishment of Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) in Arabidopsis thaliana}, pages = {XI, 162}, year = {2014}, language = {en} } @phdthesis{Omranian2014, author = {Omranian, Nooshin}, title = {Inferring gene regulatory networks and cellular phases from time-resolved transcriptomics data}, pages = {vii, 96}, year = {2014}, language = {en} } @article{GhoshCherstvyMetzler2014, author = {Ghosh, Surya K. and Cherstvy, Andrey G. and Metzler, Ralf}, title = {Non-universal tracer diffusion in crowded media of non-inert obstacles}, series = {Physical Chemistry Chemical Physics}, volume = {3}, journal = {Physical Chemistry Chemical Physics}, number = {17}, editor = {Metzler, Ralf}, publisher = {The Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, pages = {1847 -- 1858}, year = {2014}, abstract = {We study the diffusion of a tracer particle, which moves in continuum space between a lattice of excluded volume, immobile non-inert obstacles. In particular, we analyse how the strength of the tracer-obstacle interactions and the volume occupancy of the crowders alter the diffusive motion of the tracer. From the details of partitioning of the tracer diffusion modes between trapping states when bound to obstacles and bulk diffusion, we examine the degree of localisation of the tracer in the lattice of crowders. We study the properties of the tracer diffusion in terms of the ensemble and time averaged mean squared displacements, the trapping time distributions, the amplitude variation of the time averaged mean squared displacements, and the non-Gaussianity parameter of the diffusing tracer. We conclude that tracer-obstacle adsorption and binding triggers a transient anomalous diffusion. From a very narrow spread of recorded individual time averaged trajectories we exclude continuous type random walk processes as the underlying physical model of the tracer diffusion in our system. For moderate tracer-crowder attraction the motion is found to be fully ergodic, while at stronger attraction strength a transient disparity between ensemble and time averaged mean squared displacements occurs. We also put our results into perspective with findings from experimental single-particle tracking and simulations of the diffusion of tagged tracers in dense crowded suspensions. Our results have implications for the diffusion, transport, and spreading of chemical components in highly crowded environments inside living cells and other structured liquids.}, language = {en} } @article{Heidemann2015, author = {Heidemann, Birte}, title = {Post-agreement belfast : labour, work and the new subalterns in daragh carville's play this other city}, series = {Reworking postcolonialism : globalization, labour and rights}, journal = {Reworking postcolonialism : globalization, labour and rights}, publisher = {Palgrave Macmillan}, address = {New York}, isbn = {978-1-137-43592-7}, pages = {119 -- 133}, year = {2015}, language = {en} } @book{OPUS4-7705, title = {Reworking postcolonialism}, editor = {Malreddy, Pavan Kumar and Heidemann, Birte and Larsen, Ole Birk and Wilson, Janet}, publisher = {Palgrave Macmillan}, address = {New York}, isbn = {978-1-137-43592-7}, pages = {XII, 253 S.}, year = {2015}, abstract = {An interdisciplinary collection of essays, Reworking Postcolonialism explores questions of work, precarity, migration, minority and indigenous rights in relation to contemporary globalization. It focuses on the impact of global market forces on the formation of new subject positions among urban dwellers, exiles, and other disenfranchised communities. Bringing together political, economic and literary approaches to texts and events from across the postcolonial world, the essays collected here investigate the transformative effects of the global dissemination of capital and goods and the movements of people. They call for a revision of existing discourses on rights, entitlements and citizenship.}, language = {en} } @phdthesis{Jacobs2015, author = {Jacobs, Simone}, title = {Biological mechanisms of the association between proportions of fatty acids in erythrocyte membranes and type 2 diabetes risk in the EPIC-Potsdam-Study}, pages = {157}, year = {2015}, language = {en} } @article{ShinCherstvyMetzler2014, author = {Shin, Jaeoh and Cherstvy, Andrey G. and Metzler, Ralf}, title = {Kinetics of polymer looping with macromolecular crowding: effects of volume fraction and crowder size}, series = {Soft Matter}, journal = {Soft Matter}, editor = {Metzler, Ralf}, publisher = {The Royal Society of Chemistry}, address = {Cambridge}, issn = {1744-683X}, pages = {472 -- 488}, year = {2014}, abstract = {The looping of polymers such as DNA is a fundamental process in the molecular biology of living cells, whose interior is characterised by a high degree of molecular crowding. We here investigate in detail the looping dynamics of flexible polymer chains in the presence of different degrees of crowding. From the analysis of the looping-unlooping rates and the looping probabilities of the chain ends we show that the presence of small crowders typically slows down the chain dynamics but larger crowders may in fact facilitate the looping. We rationalise these non-trivial and often counterintuitive effects of the crowder size on the looping kinetics in terms of an effective solution viscosity and standard excluded volume. It is shown that for small crowders the effect of an increased viscosity dominates, while for big crowders we argue that confinement effects (caging) prevail. The tradeoff between both trends can thus result in the impediment or facilitation of polymer looping, depending on the crowder size. We also examine how the crowding volume fraction, chain length, and the attraction strength of the contact groups of the polymer chain affect the looping kinetics and hairpin formation dynamics. Our results are relevant for DNA looping in the absence and presence of protein mediation, DNA hairpin formation, RNA folding, and the folding of polypeptide chains under biologically relevant high-crowding conditions.}, language = {en} }