@article{BanerjeeStuekerSaalfrank2015, author = {Banerjee, Shiladitya and St{\"u}ker, Tony and Saalfrank, Peter}, title = {Vibrationally resolved optical spectra of modified diamondoids obtained from time-dependent correlation function methods}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies}, volume = {17}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies}, number = {29}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9084}, doi = {10.1039/C5CP02615F}, pages = {19656 -- 19669}, year = {2015}, abstract = {Optical properties of modified diamondoids have been studied theoretically using vibrationally resolved electronic absorption, emission and resonance Raman spectra. A time-dependent correlation function approach has been used for electronic two-state models, comprising a ground state (g) and a bright, excited state (e), the latter determined from linear-response, time-dependent density functional theory (TD-DFT). The harmonic and Condon approximations were adopted. In most cases origin shifts, frequency alteration and Duschinsky rotation in excited states were considered. For other cases where no excited state geometry optimization and normal mode analysis were possible or desired, a short-time approximation was used. The optical properties and spectra have been computed for (i) a set of recently synthesized sp2/sp3 hybrid species with C[double bond, length as m-dash]C double-bond connected saturated diamondoid subunits, (ii) functionalized (mostly by thiol or thione groups) diamondoids and (iii) urotropine and other C-substituted diamondoids. The ultimate goal is to tailor optical and electronic features of diamondoids by electronic blending, functionalization and substitution, based on a molecular-level understanding of the ongoing photophysics.}, language = {en} } @phdthesis{Olas2015, author = {Olas, Justyna Jadwiga}, title = {Nutrients regulate flowering time}, school = {Universit{\"a}t Potsdam}, pages = {190}, year = {2015}, language = {en} } @phdthesis{Menke2015, author = {Menke, Sebastian}, title = {Investigating the impact of intrinsic and extrinsic factors on gut bacterial communities in Namibian wildlife species using a large-scale next-generation sequencing approach}, school = {Universit{\"a}t Potsdam}, pages = {109}, year = {2015}, language = {en} } @article{LaubrockKliegl2015, author = {Laubrock, Jochen and Kliegl, Reinhold}, title = {The eye-voice span during reading aloud}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {1432}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.01432}, year = {2015}, abstract = {Although eye movements during reading are modulated by cognitive processing demands, they also reflect visual sampling of the input, and possibly preparation of output for speech or the inner voice. By simultaneously recording eye movements and the voice during reading aloud, we obtained an output measure that constrains the length of time spent on cognitive processing. Here we investigate the dynamics of the eye-voice span (EVS), the distance between eye and voice. We show that the EVS is regulated immediately during fixation of a word by either increasing fixation duration or programming a regressive eye movement against the reading direction. EVS size at the beginning of a fixation was positively correlated with the likelihood of regressions and refixations. Regression probability was further increased if the EVS was still large at the end of a fixation: if adjustment of fixation duration did not sufficiently reduce the EVS during a fixation, then a regression rather than a refixation followed with high probability. We further show that the EVS can help understand cognitive influences on fixation duration during reading: in mixed model analyses, the EVS was a stronger predictor of fixation durations than either word frequency or word length. The EVS modulated the influence of several other predictors on single fixation durations (SFDs). For example, word-N frequency effects were larger with a large EVS, especially when word N-1 frequency was low. Finally, a comparison of SFDs during oral and silent reading showed that reading is governed by similar principles in both reading modes, although EVS maintenance and articulatory processing also cause some differences. In summary, the EVS is regulated by adjusting fixation duration and/or by programming a regressive eye movement when the EVS gets too large. Overall, the EVS appears to be directly related to updating of the working memory buffer during reading.}, language = {en} } @article{LamannaKirschbaumWauricketal.2015, author = {Lamanna, Francesco and Kirschbaum, Frank and Waurick, Isabelle and Dieterich, Christoph and Tiedemann, Ralph}, title = {Cross-tissue and cross-species analysis of gene expression in skeletal muscle and electric organ of African weakly-electric fish (Teleostei; Mormyridae)}, series = {BMC Genomics}, volume = {16}, journal = {BMC Genomics}, number = {668}, publisher = {Biomed Central}, address = {London}, issn = {1471-2164}, doi = {10.1186/s12864-015-1858-9}, year = {2015}, abstract = {Background African weakly-electric fishes of the family Mormyridae are able to produce and perceive weak electric signals (typically less than one volt in amplitude) owing to the presence of a specialized, muscle-derived electric organ (EO) in their tail region. Such electric signals, also known as Electric Organ Discharges (EODs), are used for objects/prey localization, for the identification of conspecifics, and in social and reproductive behaviour. This feature might have promoted the adaptive radiation of this family by acting as an effective pre-zygotic isolation mechanism. Despite the physiological and evolutionary importance of this trait, the investigation of the genetic basis of its function and modification has so far remained limited. In this study, we aim at: i) identifying constitutive differences in terms of gene expression between electric organ and skeletal muscle (SM) in two mormyrid species of the genus Campylomormyrus: C. compressirostris and C. tshokwe, and ii) exploring cross-specific patterns of gene expression within the two tissues among C. compressirostris, C. tshokwe, and the outgroup species Gnathonemus petersii. Results Twelve paired-end (100 bp) strand-specific RNA-seq Illumina libraries were sequenced, producing circa 330 M quality-filtered short read pairs. The obtained reads were assembled de novo into four reference transcriptomes. In silico cross-tissue DE-analysis allowed us to identify 271 shared differentially expressed genes between EO and SM in C. compressirostris and C.tshokwe. Many of these genes correspond to myogenic factors, ion channels and pumps, and genes involved in several metabolic pathways. Cross-species analysis has revealed that the electric organ transcriptome is more variable in terms of gene expression levels across species than the skeletal muscle transcriptome. Conclusions The data obtained indicate that: i) the loss of contractile activity and the decoupling of the excitation-contraction processes are reflected by the down-regulation of the corresponding genes in the electric organ's transcriptome; ii) the metabolic activity of the EO might be specialized towards the production and turn-over of membrane structures; iii) several ion channels are highly expressed in the EO in order to increase excitability; iv) several myogenic factors might be down-regulated by transcription repressors in the EO.}, language = {en} } @phdthesis{Ambrogi2015, author = {Ambrogi, Martina}, title = {Application of Poly(Ionic Liquid)s for the synthesis of functional carbons}, school = {Universit{\"a}t Potsdam}, pages = {125}, year = {2015}, language = {en} } @article{PulkkinenMetzler2015, author = {Pulkkinen, Otto and Metzler, Ralf}, title = {Variance-corrected Michaelis-Menten equation predicts transient rates of single-enzyme reactions and response times in bacterial gene-regulation}, series = {Scientific reports}, journal = {Scientific reports}, number = {5}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep17820}, year = {2015}, abstract = {Many chemical reactions in biological cells occur at very low concentrations of constituent molecules. Thus, transcriptional gene-regulation is often controlled by poorly expressed transcription-factors, such as E.coli lac repressor with few tens of copies. Here we study the effects of inherent concentration fluctuations of substrate-molecules on the seminal Michaelis-Menten scheme of biochemical reactions. We present a universal correction to the Michaelis-Menten equation for the reaction-rates. The relevance and validity of this correction for enzymatic reactions and intracellular gene-regulation is demonstrated. Our analytical theory and simulation results confirm that the proposed variance-corrected Michaelis-Menten equation predicts the rate of reactions with remarkable accuracy even in the presence of large non-equilibrium concentration fluctuations. The major advantage of our approach is that it involves only the mean and variance of the substrate-molecule concentration. Our theory is therefore accessible to experiments and not specific to the exact source of the concentration fluctuations.}, language = {en} } @article{GolleMuehlbauerWicketal.2015, author = {Golle, Kathleen and M{\"u}hlbauer, Thomas and Wick, Ditmar and Granacher, Urs}, title = {Physical Fitness Percentiles of German Children Aged 9-12 Years}, series = {PLoS ONE}, volume = {10}, journal = {PLoS ONE}, number = {11}, publisher = {Public Library of Science}, address = {Lawrence, Kan.}, issn = {1932-6203}, doi = {10.1371/journal.pone.0142393}, year = {2015}, abstract = {Background Generating percentile values is helpful for the identification of children with specific fitness characteristics (i.e., low or high fitness level) to set appropriate fitness goals (i.e., fitness/health promotion and/or long-term youth athlete development). Thus, the aim of this longitudinal study was to assess physical fitness development in healthy children aged 9-12 years and to compute sex- and age-specific percentile values. Methods Two-hundred and forty children (88 girls, 152 boys) participated in this study and were tested for their physical fitness. Physical fitness was assessed using the 50-m sprint test (i.e., speed), the 1-kg ball push test, the triple hop test (i.e., upper- and lower- extremity muscular power), the stand-and-reach test (i.e., flexibility), the star run test (i.e., agility), and the 9-min run test (i.e., endurance). Age- and sex-specific percentile values (i.e., P10 to P90) were generated using the Lambda, Mu, and Sigma method. Adjusted (for change in body weight, height, and baseline performance) age- and sex-differences as well as the interactions thereof were expressed by calculating effect sizes (Cohen's d). Results Significant main effects of Age were detected for all physical fitness tests (d = 0.40-1.34), whereas significant main effects of Sex were found for upper-extremity muscular power (d = 0.55), flexibility (d = 0.81), agility (d = 0.44), and endurance (d = 0.32) only. Further, significant Sex by Age interactions were observed for upper-extremity muscular power (d = 0.36), flexibility (d = 0.61), and agility (d = 0.27) in favor of girls. Both, linear and curvilinear shaped curves were found for percentile values across the fitness tests. Accelerated (curvilinear) improvements were observed for upper-extremity muscular power (boys: 10-11 yrs; girls: 9-11 yrs), agility (boys: 9-10 yrs; girls: 9-11 yrs), and endurance (boys: 9-10 yrs; girls: 9-10 yrs). Tabulated percentiles for the 9-min run test indicated that running distances between 1,407-1,507 m, 1,479-1,597 m, 1,423-1,654 m, and 1,433-1,666 m in 9- to 12-year-old boys and 1,262-1,362 m, 1,329-1,434 m, 1,392-1,501 m, and 1,415-1,526 m in 9- to 12-year-old girls correspond to a "medium" fitness level (i.e., P40 to P60) in this population. Conclusions The observed differences in physical fitness development between boys and girls illustrate that age- and sex-specific maturational processes might have an impact on the fitness status of healthy children. Our statistical analyses revealed linear (e.g., lower-extremity muscular power) and curvilinear (e.g., agility) models of fitness improvement with age which is indicative of timed and capacity-specific fitness development pattern during childhood. Lastly, the provided age- and sex-specific percentile values can be used by coaches for talent identification and by teachers for rating/grading of children's motor performance.}, language = {en} } @article{RoderHille2015, author = {Roder, Phillip and Hille, Carsten}, title = {A Multifunctional Frontloading Approach for Repeated Recycling of a Pressure-Controlled AFM Micropipette}, series = {PLoS ONE}, volume = {10}, journal = {PLoS ONE}, number = {12}, publisher = {Public Library of Science}, address = {Lawrence, Kan.}, issn = {1932-6203}, doi = {10.1371/journal.pone.0144157}, year = {2015}, abstract = {Fluid force microscopy combines the positional accuracy and force sensitivity of an atomic force microscope (AFM) with nanofluidics via a microchanneled cantilever. However, adequate loading and cleaning procedures for such AFM micropipettes are required for various application situations. Here, a new frontloading procedure is described for an AFM micropipette functioning as a force- and pressure-controlled microscale liquid dispenser. This frontloading procedure seems especially attractive when using target substances featuring high costs or low available amounts. Here, the AFM micropipette could be filled from the tip side with liquid from a previously applied droplet with a volume of only a few μL using a short low-pressure pulse. The liquid-loaded AFM micropipettes could be then applied for experiments in air or liquid environments. AFM micropipette frontloading was evaluated with the well-known organic fluorescent dye rhodamine 6G and the AlexaFluor647-labeled antibody goat anti-rat IgG as an example of a larger biological compound. After micropipette usage, specific cleaning procedures were tested. Furthermore, a storage method is described, at which the AFM micropipettes could be stored for a few hours up to several days without drying out or clogging of the microchannel. In summary, the rapid, versatile and cost-efficient frontloading and cleaning procedure for the repeated usage of a single AFM micropipette is beneficial for various application situations from specific surface modifications through to local manipulation of living cells, and provides a simplified and faster handling for already known experiments with fluid force microscopy.}, language = {en} } @article{WarschburgerCalvanoRichteretal.2015, author = {Warschburger, Petra and Calvano, Claudia and Richter, Eike M. and Engbert, Ralf}, title = {Analysis of Attentional Bias towards Attractive and Unattractive Body Regions among Overweight Males and Females}, series = {PLoS one}, journal = {PLoS one}, number = {10}, publisher = {Public Library of Science}, address = {Lawrence, Kan.}, issn = {1932-6203}, doi = {10.1371/journal.pone.0140813}, pages = {17}, year = {2015}, abstract = {Background Body image distortion is highly prevalent among overweight individuals. Whilst there is evidence that body-dissatisfied women and those suffering from disordered eating show a negative attentional bias towards their own unattractive body parts and others' attractive body parts, little is known about visual attention patterns in the area of obesity and with respect to males. Since eating disorders and obesity share common features in terms of distorted body image and body dissatisfaction, the aim of this study was to examine whether overweight men and women show a similar attentional bias. Methods/Design We analyzed eye movements in 30 overweight individuals (18 females) and 28 normalweight individuals (16 females) with respect to the participants' own pictures as well as gender- and BMI-matched control pictures (front and back view). Additionally, we assessed body image and disordered eating using validated questionnaires. Discussion The overweight sample rated their own body as less attractive and showed a more disturbed body image. Contrary to our assumptions, they focused significantly longer on attractive compared to unattractive regions of both their own and the control body. For one's own body, this was more pronounced for women. A higher weight status and more frequent body checking predicted attentional bias towards attractive body parts. We found that overweight adults exhibit an unexpected and stable pattern of selective attention, with a distinctive focus on their own attractive body regions despite higher levels of body dissatisfaction. This positive attentional bias may either be an indicator of a more pronounced pattern of attentional avoidance or a self-enhancing strategy. Further research is warranted to clarify these results.}, language = {en} } @misc{Wischer2010, author = {Wischer, Ilse}, title = {Simone E. Pfenninger: Grammaticalization paths of english and high german existential constructions : a corpus-based study / rezensiert von Ilse Wischer}, series = {Zeitschrift f{\"u}r Dialektologie und Linguistik : ZDL}, volume = {77}, journal = {Zeitschrift f{\"u}r Dialektologie und Linguistik : ZDL}, number = {3}, issn = {0044-1449}, pages = {372 -- 375}, year = {2010}, abstract = {Rezensiertes Werk: Simone E. Pfenninger: Grammaticalization paths of english and high german existential constructions : a corpus-based study / Bern: Lang, 2009. - XI, 369 S. - (European University Studies: Series 21, Linguistics Vol. 345)}, language = {en} } @article{DiewaldWischer2013, author = {Diewald, Gariele and Wischer, Ilse}, title = {Markers of futurity in old high german and old english}, series = {Comparative Studies in Early Germanic Languages}, journal = {Comparative Studies in Early Germanic Languages}, editor = {Diewald, Gabriele and Kahlas-Karkka, Leena and Wischer, Ilse}, publisher = {Benjamins Publishing}, address = {Amsterdam}, isbn = {978-90-272-7145-7}, pages = {195 -- 215}, year = {2013}, language = {en} } @phdthesis{Pilz2016, author = {Pilz, Sonja Keren}, title = {Food and fear}, series = {Judentum - Christentum - Islam : interreligi{\"o}se Studien ; 14}, journal = {Judentum - Christentum - Islam : interreligi{\"o}se Studien ; 14}, publisher = {Ergon}, address = {W{\"u}rzburg}, isbn = {978-3-95650-140-1}, school = {Universit{\"a}t Potsdam}, pages = {192, 9}, year = {2016}, language = {en} } @book{OPUS4-8616, title = {Comparative studies in early Germanic languages}, series = {Studies language companion series ; 138}, journal = {Studies language companion series ; 138}, editor = {Diewald, Gabriele and Kahlas-Tarkka, Leena and Wischer, Ilse}, publisher = {Benjamins Publishing}, address = {Amsterdam}, isbn = {978-90272-0605-3}, publisher = {Universit{\"a}t Potsdam}, pages = {318}, year = {2013}, abstract = {This volume offers a coherent and detailed picture of the diachronic development of verbal categories of Old English, Old High German, and other Germanic languages. Starting from the observation that German and English show diverging paths in the development of verbal categories, even though they descended from a common ancestor language, the contributions present in-depth, empirically founded studies on the stages and directions of these changes combining historical comparative methods with grammaticalisation theory. This collection of papers provides the reader with an indispensable source of information on the early traces of distinct developments, thus laying the foundation for a broad-scale scenario of the grammaticalisation of verbal categories. The volume will be of particular interest to scholars of language change, grammaticalisation, and diachronic sociolinguistics; it offers important new insights for typologists and for everybody interested in the make-up of verbal categories.}, language = {en} } @book{OPUS4-8615, title = {Anglistentag 2012 Potsdam}, editor = {R{\"o}der, Katrin and Wischer, Ilse}, publisher = {Wissenschaftlicher Verlag}, address = {Trier}, isbn = {978-3-86821-488-8}, publisher = {Universit{\"a}t Potsdam}, pages = {420}, year = {2013}, abstract = {Katrin R{\"o}der and Ilse Wischer (Potsdam) Preface Section I: Recent Ireland: Visions and Revisions of Irishness from the 1990s to Today Sarah Heinz (Mannheim), Anton Kirchhofer (Oldenburg), Katharina Rennhak (Wuppertal) and Michaela Schrage-Fr{\"u}h (Mainz/Limerick) Recent Ireland: Visions and Revisions of Irishness from the 1990s to Today: Introduction Christopher Morash (Maynooth) Spectral Ireland: After the Celtic Tiger Jochen Achilles (W{\"u}rzburg) Transnational Ireland and Elizabeth Kuti's Drama Silke Stroh (M{\"u}nster) Revisioning Irish Postcolonialism: The Scottish Connection Joanna Rostek (Passau) Migration, Capital, Space: Econotopic Constellations in Recent Literature about Polish Migrants in Ireland Joachim Fischer (Limerick) Images of Germany in Irish Writing of the Last Ten Years (2002-2012) Werner Huber (Wien) The Brothers McDonagh, Filmmakers Christian Lassen (Oldenburg) The Passion of Saint Kitten, or: Desperately Seeking Mitzi, the Phantom Lady. Camp Responses to Interpellation and Subjection in Neil Jordan's Breakfast on Pluto Section II: Recent Trends in Romantic Studies Stefanie Fricke (LMU M{\"u}nchen), Rosa Karl (Erlangen-N{\"u}rnberg) and Gerold Sedlmayr (Dortmund) Recent Trends in Romantic Studies: Introduction Christoph Reinfandt (T{\"u}bingen) The Textures of Romanticism: Exploring Charlotte Smith's "Beachy Head" (1807) Ralf Haekel (G{\"o}ttingen) Romantic Textualities Anthony John Harding (Saskatchewan) British Romanticism and the Transvaluation of Reading Christa Knellwolf King (Vienna) Imperial Myth-making in the Wake of Captain Cook's Death Monika Class (King's College London) Medical Case Narratives across Disciplinary and National Boundaries around 1800 Ute Berns (Hamburg) Romantic Poetry, Scientific Discourse and the Aesthetics of Nature Section III: Apocalypse and Literature Sibylle Baumbach (Mainz) and Anja M{\"u}ller-Wood (Mainz) Apocalypse and Literature: Introduction Susanne Schmid (Berlin) Philip Pullman's His Dark Materials and Resistance to the Apocalypse Bj{\"o}rn Quiring (Berlin) Judging the New Bloomusalem: Persistent Apocalyptic Remnants in Joyce's Ulysses Heike Hartung (Potsdam) Apocalypse and Old Age: Imminent Ends and Lacking Futures Apocalypse and Literature: Summaries Section IV: Comics and Graphic Novels Dirk Vanderbeke (Jena), Sebastian Domsch (Greifswald) and Astrid B{\"o}ger (Hamburg) Comics and Graphic Novels: Introduction Martin Rowson (London) Towards a Theory of Literary Adaptation in Comic Book Format: A Graphic Response Nicola Glaubitz (Darmstadt) Vernacular Modernism: Martin Rowson's The Waste Land Ellen Gr{\"u}nkemeier (Hannover) Locating The League of Extraordinary Gentlemen in Victorian Literature and (Popular) Culture Sandra Heinen (Wuppertal) 'Indigenizing the Comic Book Medium': Techniques of Storytelling in Indian Graphic Novels Felicitas Meifert-Menhard (M{\"u}nchen) Evading the Sequence: Choose Your Own Comic Therese-Marie Meyer (Halle-Wittenberg) "My Country, My England": Warren Ellis's Graphic Novels and England at War Sandra Martina Schwab (Mainz) Richard Doyle's Sequential Art in Punch Section V: Electronic Discourse Markus Bieswanger (Bayreuth) and Andrea Sand (Trier) Electronic Discourse: Introduction Klaus P. Schneider (Bonn) Emerging E-mail Etiquette: Lay Perceptions of Appropriateness in Electronic Discourse Christian R. Hoffmann (Augsburg) E(-lectronic) Schmoozing? A Cross-Generic Study of Compliments in Blog Comments Jenny Arendholz (Augsburg) "How to stop strange people speaking to me" - A Syntactic and Interpersonal Perspective on Offering A dvice Online Tanja Angelovska and Angela Hahn (M{\"u}nchen) Features of Spoken L3 English in an Online Discourse Dagmar Deuber (M{\"u}nster) and Andrea Sand (Trier) Computer-Mediated Communication in Singapore: Spoken Language Features in Weblogs and a Discussion Forum Christian Mair (Freiburg) Corpus Approaches to the Vernacular Web: Post-Colonial Diasporic Forums in West Africa and the Caribbean}, language = {en} } @phdthesis{Schiess2015, author = {Schiess, Sonja}, title = {Effects of glucotropaeolin and its breakdown product benzyl isothiocyanate on metabolic, endocrine, and inflammatory parameters in humans}, school = {Universit{\"a}t Potsdam}, pages = {115}, year = {2015}, language = {en} } @phdthesis{Schwarz2015, author = {Schwarz, Dana}, title = {Nanoporous melamine resin materials}, school = {Universit{\"a}t Potsdam}, pages = {146}, year = {2015}, language = {en} } @phdthesis{Zibulski2014, author = {Zibulski, Romy}, title = {Taxonomic composition and biochemical and isotopic characteristics of North-Siberian mosses and their application to the palaeoecological reconstruction of tundra polygon development}, pages = {ii, 127}, year = {2014}, language = {en} } @phdthesis{Chen2015, author = {Chen, Zupeng}, title = {Novel strategies to improve (photo)catalytic performance of carbon nitride-based composites}, pages = {ii, 137}, year = {2015}, language = {en} } @phdthesis{Sborikas2015, author = {Sborikas, Martynas}, title = {Preparation and characterization of acoustic electret and electromechanical properties of polypropylene ferroelectrets}, pages = {129}, year = {2015}, language = {en} } @phdthesis{Lohren2015, author = {Lohren, Hanna}, title = {Mechanisms of mercury species-mediated neurotoxicity}, school = {Universit{\"a}t Potsdam}, pages = {141, viii}, year = {2015}, language = {en} } @phdthesis{Weits2015, author = {Weits, Daniel}, title = {Regulation of the molecular response to low oxygen in plants}, school = {Universit{\"a}t Potsdam}, pages = {113}, year = {2015}, language = {en} } @phdthesis{Thieme2015, author = {Thieme, Christoph J.}, title = {Sequence and structure determinants of microRNA maturation and the elucidation of RNA transport in plants}, school = {Universit{\"a}t Potsdam}, pages = {137}, year = {2015}, language = {en} } @article{BodrovaChechkinCherstvyetal.2015, author = {Bodrova, Anna and Chechkin, Aleksei V. and Cherstvy, Andrey G. and Metzler, Ralf}, title = {Quantifying non-ergodic dynamics of force-free granular gases}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, number = {17}, issn = {1463-9084}, doi = {10.1039/C5CP02824H}, pages = {21791 -- 21798}, year = {2015}, abstract = {Brownianmotion is ergodic in the Boltzmann-Khinchin sense that long time averages of physical observables such as the mean squared displacement provide the same information as the corresponding ensemble average, even at out-of-equilibrium conditions. This property is the fundamental prerequisite for single particle tracking and its analysis in simple liquids. We study analytically and by event-driven molecular dynamics simulations the dynamics of force-free cooling granular gases and reveal a violation of ergodicity in this Boltzmann- Khinchin sense as well as distinct ageing of the system. Such granular gases comprise materials such as dilute gases of stones, sand, various types of powders, or large molecules, and their mixtures are ubiquitous in Nature and technology, in particular in Space. We treat—depending on the physical-chemical properties of the inter-particle interaction upon their pair collisions—both a constant and a velocity-dependent (viscoelastic) restitution coefficient e. Moreover we compare the granular gas dynamics with an effective single particle stochastic model based on an underdamped Langevin equation with time dependent diffusivity. We find that both models share the same behaviour of the ensemble mean squared displacement (MSD) and the velocity correlations in the limit of weak dissipation. Qualitatively, the reported non-ergodic behaviour is generic for granular gases with any realistic dependence of e on the impact velocity of particles.}, language = {en} } @article{MaiBoyeYuanetal.2015, author = {Mai, Tobias and Boye, Susanne and Yuan, Jiayin and V{\"o}lkel, Antje and Gr{\"a}wert, Marlies and G{\"u}nter, Christina and Lederer, Albena and Taubert, Andreas}, title = {Poly(ethylene oxide)-based block copolymers with very high molecular weights for biomimetic calcium phosphate mineralization}, series = {RSC Advances : an international journal to further the chemical sciences}, journal = {RSC Advances : an international journal to further the chemical sciences}, number = {5}, publisher = {RSC Publishing}, address = {London}, issn = {2046-2069}, doi = {10.1039/c5ra20035k}, pages = {103494 -- 103505}, year = {2015}, abstract = {The present article is among the first reports on the effects of poly(ampholyte)s and poly(betaine)s on the biomimetic formation of calcium phosphate. We have synthesized a series of di- and triblock copolymers based on a non-ionic poly(ethylene oxide) block and several charged methacrylate monomers, 2-(trimethylammonium)ethyl methacrylate chloride, 2-((3-cyanopropyl)-dimethylammonium)ethyl methacrylate chloride, 3-sulfopropyl methacrylate potassium salt, and [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide. The resulting copolymers are either positively charged, ampholytic, or betaine block copolymers. All the polymers have very high molecular weights of over 106 g mol-1. All polymers are water-soluble and show a strong effect on the precipitation and dissolution of calcium phosphate. The strongest effects are observed with triblock copolymers based on a large poly(ethylene oxide) middle block (nominal Mn = 100 000 g mol-1). Surprisingly, the data show that there is a need for positive charges in the polymers to exert tight control over mineralization and dissolution, but that the exact position of the charge in the polymer is of minor importance for both calcium phosphate precipitation and dissolution.}, language = {en} } @article{MardoukhiJeonMetzler2015, author = {Mardoukhi, Yousof and Jeon, Jae-Hyung and Metzler, Ralf}, title = {Geometry controlled anomalous diffusion in random fractal geometries}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, number = {17}, publisher = {Wiley-VCH Verl.}, address = {Weinheim}, issn = {1439-7641}, doi = {10.1039/c5cp03548a}, pages = {30134 -- 30147}, year = {2015}, abstract = {We investigate the ergodic properties of a random walker performing (anomalous) diffusion on a random fractal geometry. Extensive Monte Carlo simulations of the motion of tracer particles on an ensemble of realisations of percolation clusters are performed for a wide range of percolation densities. Single trajectories of the tracer motion are analysed to quantify the time averaged mean squared displacement (MSD) and to compare this with the ensemble averaged MSD of the particle motion. Other complementary physical observables associated with ergodicity are studied, as well. It turns out that the time averaged MSD of individual realisations exhibits non-vanishing fluctuations even in the limit of very long observation times as the percolation density approaches the critical value. This apparent non-ergodic behaviour concurs with the ergodic behaviour on the ensemble averaged level. We demonstrate how the non-vanishing fluctuations in single particle trajectories are analytically expressed in terms of the fractal dimension and the cluster size distribution of the random geometry, thus being of purely geometrical origin. Moreover, we reveal that the convergence scaling law to ergodicity, which is known to be inversely proportional to the observation time T for ergodic diffusion processes, follows a power-law BT� h with h o 1 due to the fractal structure of the accessible space. These results provide useful measures for differentiating the subdiffusion on random fractals from an otherwise closely related process, namely, fractional Brownian motion. Implications of our results on the analysis of single particle tracking experiments are provided.}, language = {en} } @article{KuschpelLiuSchadetal.2015, author = {Kuschpel, Maxim S. and Liu, Shuyan and Schad, Daniel and Heinzel, Stephan and Heinz, Andreas and Rapp, Michael A.}, title = {Differential effects of wakeful rest, music and video game playing on working memory performance in the n-back task}, series = {Frontiers in psychology}, journal = {Frontiers in psychology}, number = {6}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.01683}, year = {2015}, abstract = {The interruption of learning processes by breaks filled with diverse activities is common in everyday life. We investigated the effects of active computer gaming and passive relaxation (rest and music) breaks on working memory performance. Young adults were exposed to breaks involving (i) eyes-open resting, (ii) listening to music and (iii) playing the video game "Angry Birds" before performing the n-back working memory task. Based on linear mixed-effects modeling, we found that playing the "Angry Birds" video game during a short learning break led to a decline in task performance over the course of the task as compared to eyes-open resting and listening to music, although overall task performance was not impaired. This effect was associated with high levels of daily mind wandering and low self-reported ability to concentrate. These findings indicate that video games can negatively affect working memory performance over time when played in between learning tasks. We suggest further investigation of these effects because of their relevance to everyday activity.}, language = {en} } @phdthesis{Jung2015, author = {Jung, J{\"o}rg}, title = {Efficient credit based server load balancing}, school = {Universit{\"a}t Potsdam}, pages = {353}, year = {2015}, language = {en} } @phdthesis{Allroggen2015, author = {Allroggen, Niklas}, title = {Observation of subsurface flow from the surface : applications of ground-penetrating radar}, school = {Universit{\"a}t Potsdam}, pages = {67}, year = {2015}, language = {en} } @phdthesis{Heyneke2015, author = {Heyneke, Elmien}, title = {The role of the calcineurin B-like interacting protein kinase, CIPK14 in regulating plant nutrient metabolism}, school = {Universit{\"a}t Potsdam}, pages = {135}, year = {2015}, language = {en} } @phdthesis{Shivanand2015, author = {Shivanand, Lathe Rahul}, title = {DUF1068 protein family members are involved in cell wall formation in Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {393}, year = {2015}, language = {en} } @phdthesis{Abon2015, author = {Abon, Catherine Cristobal}, title = {Radar-based rainfall retrieval for flood forecasting in a meso-scale catchment}, school = {Universit{\"a}t Potsdam}, pages = {93 S.}, year = {2015}, language = {en} } @article{SbragagliaLamannaMatetal.2015, author = {Sbragaglia, Valerio and Lamanna, Francesco and Mat, Audrey M. and Rotllant, Guiomar and Joly, Silvia and Ketmaier, Valerio and de la Iglesia, Horacio O. and Aguzzi, Jacopo}, title = {Identification, Characterization, and Diel Pattern of Expression of Canonical Clock Genes in Nephrops norvegicus (Crustacea: Decapoda) Eyestalk}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {11}, publisher = {Public Library of Science}, address = {Lawrence}, issn = {1932-6203}, doi = {10.1371/journal.pone.0141893}, year = {2015}, abstract = {The Norway lobster, Nephrops norvegicus, is a burrowing decapod with a rhythmic burrow emergence (24 h) governed by the circadian system. It is an important resource for European fisheries and its behavior deeply affects its availability. The current knowledge of Nephrops circadian biology is phenomenological as it is currently the case for almost all crustaceans. In attempt to elucidate the putative molecular mechanisms underlying circadian gene regulation in Nephrops, we used a transcriptomics approach on cDNA extracted from the eyestalk, a structure playing a crucial role in controlling behavior of decapods. We studied 14 male lobsters under 12-12 light-darkness blue light cycle. We used the Hiseq 2000 Illumina platform to sequence two eyestalk libraries (under light and darkness conditions) obtaining about 90 millions 100-bp paired-end reads. Trinity was used for the de novo reconstruction of transcriptomes; the size at which half of all assembled bases reside in contigs (N50) was equal to 1796 (light) and 2055 (darkness). We found a list of candidate clock genes and focused our attention on canonical ones: timeless, period, clock and bmal1. The cloning of assembled fragments validated Trinity outputs. The putative Nephrops clock genes showed high levels of identity (blastx on NCBI) with known crustacean clock gene homologs such as Eurydice pulchra (period: 47\%, timeless: 59\%, bmal1: 79\%) and Macrobrachium rosenbergii (clock: 100\%). We also found a vertebrate-like cryptochrome 2. RT-qPCR showed that only timeless had a robust diel pattern of expression. Our data are in accordance with the current knowledge of the crustacean circadian clock, reinforcing the idea that the molecular clockwork of this group shows some differences with the established model in Drosophila melanogaster.}, language = {en} } @article{VormoorLawrenceHeistermannetal.2015, author = {Vormoor, Klaus Josef and Lawrence, D. and Heistermann, Maik and Bronstert, Axel}, title = {Climate change impacts on the seasonality and generation processes of floods}, series = {Hydrology and earth system sciences : HESS}, volume = {19}, journal = {Hydrology and earth system sciences : HESS}, number = {2}, publisher = {Copernicus Publications}, address = {G{\"o}ttingen}, issn = {1027-5606}, doi = {10.5194/hess-19-913-2015}, pages = {913 -- 931}, year = {2015}, abstract = {Climate change is likely to impact the seasonality and generation processes of floods in the Nordic countries, which has direct implications for flood risk assessment, design flood estimation, and hydropower production management. Using a multi-model/multi-parameter approach to simulate daily discharge for a reference (1961-1990) and a future (2071-2099) period, we analysed the projected changes in flood seasonality and generation processes in six catchments with mixed snowmelt/rainfall regimes under the current climate in Norway. The multi-model/multi-parameter ensemble consists of (i) eight combinations of global and regional climate models, (ii) two methods for adjusting the climate model output to the catchment scale, and (iii) one conceptual hydrological model with 25 calibrated parameter sets. Results indicate that autumn/winter events become more frequent in all catchments considered, which leads to an intensification of the current autumn/winter flood regime for the coastal catchments, a reduction of the dominance of spring/summer flood regimes in a high-mountain catchment, and a possible systematic shift in the current flood regimes from spring/summer to autumn/winter in the two catchments located in northern and south-eastern Norway. The changes in flood regimes result from increasing event magnitudes or frequencies, or a combination of both during autumn and winter. Changes towards more dominant autumn/winter events correspond to an increasing relevance of rainfall as a flood generating process (FGP) which is most pronounced in those catchments with the largest shifts in flood seasonality. Here, rainfall replaces snowmelt as the dominant FGP primarily due to increasing temperature.We further analysed the ensemble components in contributing to overall uncertainty in the projected changes and found that the climate projections and the methods for downscaling or bias correction tend to be the largest contributors. The relative role of hydrological parameter uncertainty, however, is highest for those catchments showing the largest changes in flood seasonality, which confirms the lack of robustness in hydrological model parameterization for simulations under transient hydrometeorological conditions.}, language = {en} } @phdthesis{Karo2015, author = {Karo, Nihad Majeed}, title = {Metamorphic evolution of the Northern Zagros Suture Zone (NZSZ)}, school = {Universit{\"a}t Potsdam}, pages = {127}, year = {2015}, language = {en} } @phdthesis{Siegel2015, author = {Siegel, Daniel}, title = {Binary neutron star mergers and short gamma-ray bursts}, school = {Universit{\"a}t Potsdam}, pages = {255}, year = {2015}, language = {en} } @phdthesis{Timofeeva2015, author = {Timofeeva, Nadezda}, title = {Effect of ions and amino-acid sequence on collagen structure}, school = {Universit{\"a}t Potsdam}, pages = {121}, year = {2015}, language = {en} } @incollection{Lottes2014, author = {Lottes, G{\"u}nther}, title = {Language and Content}, series = {Perspectives on English revolutionary republicanism}, booktitle = {Perspectives on English revolutionary republicanism}, publisher = {Ashgate}, address = {Farnham}, publisher = {Universit{\"a}t Potsdam}, pages = {53 -- 61}, year = {2014}, language = {en} } @article{WiemannMahlberg2014, author = {Wiemann, Dirk and Mahlberg, Gaby}, title = {Introduction : Perspectives on English revolutionary republicanism}, series = {Perspectives on English revolutionary republicanism}, journal = {Perspectives on English revolutionary republicanism}, editor = {Wiemann, Dirk and Mahlberg, Gaby}, publisher = {Ashgate}, address = {Farnham}, pages = {1 -- 12}, year = {2014}, language = {en} } @book{WiemannMahlbergDzelzainisetal.2014, author = {Wiemann, Dirk and Mahlberg, Gaby and Dzelzainis, Martin and Cuttica, Cesare and Lottes, G{\"u}nther and Davis, J. C. and Pankratz, Anette and Sedlmayr, Gerold and Vallance, Edward and Vanderbeke, Dirk and Borot, Luc and Champion, Justin and Burgess, Glenn}, title = {Perspectives on English revolutionary republicanism}, editor = {Wiemann, Dirk and Mahlberg, Gaby}, publisher = {Ashgate}, address = {Farnham}, isbn = {978-1-4094-5567-7}, publisher = {Universit{\"a}t Potsdam}, pages = {IX, 228}, year = {2014}, abstract = {Perspectives on English Revolutionary Republicanism takes stock of developments in the scholarship of seventeenth-century English republicanism by looking at the movements and schools of thought that have shaped the field over the decades: the linguistic turn, the cultural turn and the religious turn. While scholars of seventeenth-century republicanism share their enthusiasm for their field, they have approached their subject in diverse ways. The contributors to the present volume have taken the opportunity to bring these approaches together in a number of case studies covering republican language, republican literary and political culture, and republican religion, to paint a lively picture of the state of the art in republican scholarship. The volume begins with three chapters influenced by the theory and methodology of the linguistic turn, before moving on to address cultural history approaches to English republicanism, including both literary culture and (practical) political culture. The final section of the volume looks at how religion intersected with ideas of republican thought. Taken together the essays demonstrate the vitality and diversity of what was once regarded as a narrow topic of political research.}, language = {en} } @phdthesis{Swiadek2015, author = {Swiadek, Magdalena Agnieszka}, title = {Hybrid necrosis in local populations of Arabidopsis thaliana}, school = {Universit{\"a}t Potsdam}, pages = {109}, year = {2015}, language = {en} } @phdthesis{ElKassar2015, author = {El Kassar, Nadja}, title = {Towards a theory of epistemically significant perception}, publisher = {De Gruyter}, address = {Berlin}, isbn = {978-3-11-044563-3}, school = {Universit{\"a}t Potsdam}, pages = {360}, year = {2015}, abstract = {How does perceptual experience make us knowledgeable? This book argues that the answer lies in the nature of perceptual experience: this experience involves conceptual capacities and is a relation between perceiver and world. The author develops her position via a critical examination of conceptualist and relationist theories of perception. A discussion of recent work in vision science rounds up this contribution to the philosophy of perception.}, language = {en} } @phdthesis{Heistermann2015, author = {Heistermann, Maik}, title = {Advancing weather radar in hydrology}, school = {Universit{\"a}t Potsdam}, pages = {228}, year = {2015}, language = {en} } @phdthesis{BaerHenney2015, author = {Baer-Henney, Dinah}, title = {Learners' Little Helper}, school = {Universit{\"a}t Potsdam}, pages = {135}, year = {2015}, language = {en} } @phdthesis{Grune2015, author = {Grune, Jana}, title = {Effects of a novel non-steroidal mineralocorticoid receptor antagonist on cardiac hypertrophy}, school = {Universit{\"a}t Potsdam}, pages = {98}, year = {2015}, language = {en} } @article{MoserTschakertMuelleretal.2015, author = {Moser, Othmar and Tschakert, Gerhard and M{\"u}ller, Alexander and Groeschl, Werner and Pieber, Thomas R. and Obermayer-Pietsch, Barbara and Koehler, Gerd and Hofmann, Peter}, title = {Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {8}, publisher = {Public Library of Science}, address = {Lawrence}, issn = {1932-6203}, doi = {10.1371/journal.pone.0136489}, pages = {17}, year = {2015}, abstract = {Introduction We investigated blood glucose (BG) and hormone response to aerobic high-intensity interval exercise (HIIE) and moderate continuous exercise (CON) matched for mean load and duration in type 1 diabetes mellitus (T1DM). Material and Methods Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A) and above (B) the first lactate turn point and below the second lactate turn point (C) on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/ Novo Nordisk, Denmark). Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25\% (A), 50\% (B), and 75\% (C) dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system. Results BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006) and B (p = 0.004) and respiratory exchange ratio for A (p = 0.003) and B (p = 0.003) were significantly higher compared to CON but not for C. Conclusion Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM.}, language = {en} } @article{JahnBuschmannHille2015, author = {Jahn, Karolina and Buschmann, Volker and Hille, Carsten}, title = {Simultaneous Fluorescence and Phosphorescence Lifetime Imaging Microscopy in Living Cells}, series = {Scientific Reports}, journal = {Scientific Reports}, number = {5}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep14334}, pages = {13}, year = {2015}, abstract = {In living cells, there are always a plethora of processes taking place at the same time. Their precise regulation is the basis of cellular functions, since small failures can lead to severe dysfunctions. For a comprehensive understanding of intracellular homeostasis, simultaneous multiparameter detection is a versatile tool for revealing the spatial and temporal interactions of intracellular parameters. Here, a recently developed time-correlated single-photon counting (TCSPC) board was evaluated for simultaneous fluorescence and phosphorescence lifetime imaging microscopy (FLIM/PLIM). Therefore, the metabolic activity in insect salivary glands was investigated by recording ns-decaying intrinsic cellular fluorescence, mainly related to oxidized flavin adenine dinucleotide (FAD) and the μs-decaying phosphorescence of the oxygen-sensitive ruthenium-complex Kr341. Due to dopamine stimulation, the metabolic activity of salivary glands increased, causing a higher pericellular oxygen consumption and a resulting increase in Kr341 phosphorescence decay time. Furthermore, FAD fluorescence decay time decreased, presumably due to protein binding, thus inducing a quenching of FAD fluorescence decay time. Through application of the metabolic drugs antimycin and FCCP, the recorded signals could be assigned to a mitochondrial origin. The dopamine-induced changes could be observed in sequential FLIM and PLIM recordings, as well as in simultaneous FLIM/PLIM recordings using an intermediate TCSPC timing resolution.}, language = {en} } @phdthesis{Krishnamoorthy2015, author = {Krishnamoorthy, Praveen}, title = {Regulatory roles of Ptdlns(4,5)P2 in trafficking of the cellulose synthase complex and identification of distinct plasma membrane localisation patterns of Arabidopsis PiP5-kinases}, school = {Universit{\"a}t Potsdam}, pages = {133}, year = {2015}, language = {en} } @phdthesis{HeidemannMalreddy2015, author = {Heidemann-Malreddy, Birte}, title = {Lost in a liminal space?}, school = {Universit{\"a}t Potsdam}, pages = {300}, year = {2015}, language = {en} } @phdthesis{Ogone2015, author = {Ogone, James Odhiambo}, title = {Domesticating modernity in Africa}, school = {Universit{\"a}t Potsdam}, pages = {229}, year = {2015}, language = {en} } @phdthesis{Tassler2015, author = {Taßler, Stephanie}, title = {Physical-Chemical Investigation of newly-synthesised Lysine-Based Amino-Functionalised Lipids for gene transfection in 2D and 3D model systems}, school = {Universit{\"a}t Potsdam}, pages = {142}, year = {2015}, language = {en} } @article{Kroener2015, author = {Kr{\"o}ner, Dominik}, title = {Laser-driven electron dynamics for circular dichroism in mass spectrometry}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, volume = {29}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, number = {17}, publisher = {The Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/C5CP02193F}, pages = {19643 -- 19655}, year = {2015}, abstract = {The distinction of enantiomers is a key aspect of chemical analysis. In mass spectrometry the distinction of enantiomers has been achieved by ionizing the sample with circularly polarized laser pulses and comparing the ion yields for light of opposite handedness. While resonant excitation conditions are expected to be most efficient, they are not required for the detection of a circular dichroism (CD) in the ion yield. However, the prediction of the size and sign of the circular dichroism becomes challenging if non-resonant multiphoton excitations are used to ionize the sample. Employing femtosecond laser pulses to drive electron wavepacket dynamics based on ab initio calculations, we attempt to reveal underlying mechanisms that determine the CD under non-resonant excitation conditions. Simulations were done for (R)-1,2-propylene oxide, using time-dependent configuration interaction singles with perturbative doubles (TD-CIS(D)) and the aug-cc-pVTZ basis set. Interactions between the electric field and the electric dipole and quadrupole as well as between the magnetic field and the magnetic dipole were explicitly accounted for. The ion yield was determined by treating states above the ionization potential as either stationary or non-stationary with energy-dependent lifetimes based on an approved heuristic approach. The observed population dynamics do not allow for a simple interpretation, because of highly non-linear interactions. Still, the various transition pathways are governed by resonant enantiospecific n-photon excitation, with preferably high transition dipole moments, which eventually dominate the CD in the ionized population.}, language = {en} } @article{LohrenBornhorstGallaetal.2015, author = {Lohren, Hanna and Bornhorst, Julia and Galla, Hans-Joachim and Schwerdtle, Tanja}, title = {The blood-cerebrospinal fluid barrier}, series = {Metallomics : integrated biometal science}, volume = {10}, journal = {Metallomics : integrated biometal science}, number = {7}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1756-5901}, doi = {10.1039/C5MT00171D}, pages = {1420 -- 1430}, year = {2015}, abstract = {Exposure to organic mercury compounds promotes primarily neurological effects. Although methylmercury is recognized as a potent neurotoxicant, its transfer into the central nervous system (CNS) is not fully evaluated. While methylmercury and thiomersal pass the blood-brain barrier, limited data are available regarding the second brain regulating interface, the blood-cerebrospinal fluid (CSF) barrier. This novel study was designed to investigate the effects of organic as well as inorganic mercury compounds on, and their transfer across, a porcine in vitro model of the blood-CSF barrier for the first time. The barrier system is significantly more sensitive towards organic Hg compounds as compared to inorganic compounds regarding the endpoints cytotoxicity and barrier integrity. Whereas there are low transfer rates from the blood side to the CSF side, our results strongly indicate an active transfer of the organic mercury compounds out of the CSF. These results are the first to demonstrate an efflux of organic mercury compounds regarding the CNS and provide a completely new approach in the understanding of mercury compounds specific transport.}, language = {en} } @article{MeyerRaberEbertetal.2015, author = {Meyer, S. and Raber, G. and Ebert, Franziska and Leffers, L. and M{\"u}ller, Sandra Marie and Taleshi, M. S. and Francesconi, Kevin A. and Schwerdtle, Tanja}, title = {In vitro toxicological characterisation of arsenic-containing fatty acids and three of their metabolites}, series = {Toxicology research}, volume = {5}, journal = {Toxicology research}, number = {4}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2045-4538}, doi = {10.1039/c5tx00122f}, pages = {1289 -- 1296}, year = {2015}, abstract = {Arsenic-containing fatty acids are a group of fat-soluble arsenic species (arsenolipids) which are present in marine fish and other seafood. Recently, it has been shown that arsenic-containing hydrocarbons, another group of arsenolipids, exert toxicity in similar concentrations comparable to arsenite although the toxic modes of action differ. Hence, a risk assessment of arsenolipids is urgently needed. In this study the cellular toxicity of a saturated (AsFA 362) and an unsaturated (AsFA 388) arsenic-containing fatty acid and three of their proposed metabolites (DMAV, DMAPr and thio-DMAPr) were investigated in human liver cells (HepG2). Even though both arsenic-containing fatty acids were less toxic as compared to arsenic-containing hydrocarbons and arsenite, significant effects were observable at μM concentrations. DMAV causes effects in a similar concentration range and it could be seen that it is metabolised to its highly toxic thio analogue thio-DMAV in HepG2 cells. Nevertheless, DMAPr and thio-DMAPr did not exert any cytotoxicity. In summary, our data indicate that risks to human health related to the presence of arsenic-containing fatty acids in marine food cannot be excluded. This stresses the need for a full in vitro and in vivo toxicological characterisation of these arsenolipids.}, language = {en} } @phdthesis{Pfestorf2015, author = {Pfestorf, Hans}, title = {Land use intensity and insect root herbivores}, school = {Universit{\"a}t Potsdam}, pages = {161}, year = {2015}, language = {en} } @phdthesis{Zupok2015, author = {Zupok, Arkadiusz}, title = {The psbB-operon is a major locus for plastome-genome incompatibility in Oenothera}, school = {Universit{\"a}t Potsdam}, pages = {108}, year = {2015}, language = {en} } @phdthesis{Hainich2015, author = {Hainich, Rainer}, title = {The Wolf-Rayet stars of the nitrogen sequence in environments of different metallicities}, school = {Universit{\"a}t Potsdam}, pages = {161}, year = {2015}, language = {en} } @article{KirchheckerTroegerMuellerBakeetal.2015, author = {Kirchhecker, Sarah and Tr{\"o}ger-M{\"u}ller, Steffen and Bake, Sebastian and Antonietti, Markus and Taubert, Andreas and Esposito, Davido}, title = {Renewable pyridinium ionic liquids from the continuous hydrothermal decarboxylation of furfural-amino acid derived pyridinium zwitterions}, series = {Green chemistry}, volume = {8}, journal = {Green chemistry}, number = {17}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9262}, doi = {10.1039/c5gc00913h}, pages = {4151 -- 4156}, year = {2015}, abstract = {Fully renewable pyridinium ionic liquids were synthesised via the hydrothermal decarboxylation of pyridinium zwitterions derived from furfural and amino acids in flow. The functionality of the resulting ionic liquid (IL) can be tuned by choice of different amino acids as well as different natural carboxylic acids as the counterions. A representative member of this new class of ionic liquids was successfully used for the synthesis of ionogels and as a solvent for the Heck coupling.}, language = {en} } @article{BartoloniJinMarcaidaetal.2015, author = {Bartoloni, Marco and Jin, Xian and Marcaida, Maria Jos{\´e} and Banha, Joao and Dibonaventura, Ivan and Bongoni, Swathi and Bartho, Kathrin and Gr{\"a}bner, Olivia and Sefkow, Michael and Darbre, Tamis and Reymond, Jean-Louis}, title = {Bridged bicyclic peptides as potential drug scaffolds}, series = {Chemical Science}, volume = {10}, journal = {Chemical Science}, number = {6}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2041-6520}, doi = {10.1039/C5SC01699A}, pages = {5473 -- 5490}, year = {2015}, abstract = {Double cyclization of short linear peptides obtained by solid phase peptide synthesis was used to prepare bridged bicyclic peptides (BBPs) corresponding to the topology of bridged bicyclic alkanes such as norbornane. Diastereomeric norbornapeptides were investigated by 1H-NMR, X-ray crystallography and CD spectroscopy and found to represent rigid globular scaffolds stabilized by intramolecular backbone hydrogen bonds with scaffold geometries determined by the chirality of amino acid residues and sharing structural features of β-turns and α-helices. Proteome profiling by capture compound mass spectrometry (CCMS) led to the discovery of the norbornapeptide 27c binding selectively to calmodulin as an example of a BBP protein binder. This and other BBPs showed high stability towards proteolytic degradation in serum.}, language = {en} } @article{SchulzeUtechtMoldtetal.2015, author = {Schulze, Michael and Utecht, Manuel Martin and Moldt, Thomas and Przyrembel, Daniel and Gahl, Cornelius and Weinelt, Martin and Saalfrank, Peter and Tegeder, Petra}, title = {Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, volume = {27}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies}, number = {17}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/c5cp03093e}, pages = {18079 -- 18086}, year = {2015}, abstract = {The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16\% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10-18 cm2 for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions.}, language = {en} } @article{GuhaWarsinkeTientcheuetal.2015, author = {Guha, S. and Warsinke, A. and Tientcheu, Ch. M. and Schmalz, K. and Meliani, C. and Wenger, Ch.}, title = {Label free sensing of creatinine using a 6 GHz CMOS near-field dielectric immunosensor}, series = {The analyst : the analytical journal of the Royal Society of Chemistry}, volume = {9}, journal = {The analyst : the analytical journal of the Royal Society of Chemistry}, number = {140}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {0003-2654}, doi = {10.1039/c4an02194k}, pages = {3019 -- 3027}, year = {2015}, abstract = {In this work we present a CMOS high frequency direct immunosensor operating at 6 GHz (C-band) for label free determination of creatinine. The sensor is fabricated in standard 0.13 μm SiGe:C BiCMOS process. The report also demonstrates the ability to immobilize creatinine molecules on a Si3N4 passivation layer of the standard BiCMOS/CMOS process, therefore, evading any further need of cumbersome post processing of the fabricated sensor chip. The sensor is based on capacitive detection of the amount of non-creatinine bound antibodies binding to an immobilized creatinine layer on the passivated sensor. The chip bound antibody amount in turn corresponds indirectly to the creatinine concentration used in the incubation phase. The determination of creatinine in the concentration range of 0.88-880 μM is successfully demonstrated in this work. A sensitivity of 35 MHz/10 fold increase in creatinine concentration (during incubation) at the centre frequency of 6 GHz is gained by the immunosensor. The results are compared with a standard optical measurement technique and the dynamic range and sensitivity is of the order of the established optical indication technique. The C-band immunosensor chip comprising an area of 0.3 mm2 reduces the sensing area considerably, therefore, requiring a sample volume as low as 2 μl. The small analyte sample volume and label free approach also reduce the experimental costs in addition to the low fabrication costs offered by the batch fabrication technique of CMOS/BiCMOS process.}, language = {en} } @article{NiedlBeta2015, author = {Niedl, Robert Raimund and Beta, Carsten}, title = {Hydrogel-driven paper-based microfluidics}, series = {LAB on a chip : miniaturisation for chemistry and biology}, volume = {11}, journal = {LAB on a chip : miniaturisation for chemistry and biology}, number = {15}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1473-0197}, doi = {10.1039/c5lc00276a}, pages = {2452 -- 2459}, year = {2015}, abstract = {Paper-based microfluidics provide an inexpensive, easy to use technology for point-of-care diagnostics in developing countries. Here, we combine paper-based microfluidic devices with responsive hydrogels to add an entire new class of functions to these versatile low-cost fluidic systems. The hydrogels serve as fluid reservoirs. In response to an external stimulus, e.g. an increase in temperature, the hydrogels collapse and release fluid into the structured paper substrate. In this way, chemicals that are either stored on the paper substrate or inside the hydrogel pads can be dissolved, premixed, and brought to reaction to fulfill specific analytic tasks. We demonstrate that multi-step sequences of chemical reactions can be implemented in a paper-based system and operated without the need for external precision pumps. We exemplify this technology by integrating an antibody-based E. coli test on a small and easy to use paper device.}, language = {en} } @article{NoechelReddyWangetal.2015, author = {N{\"o}chel, Ulrich and Reddy, Chaganti Srinivasa and Wang, Ke and Cui, Jing and Zizak, Ivo and Behl, Marc and Kratz, Karl and Lendlein, Andreas}, title = {Nanostructural changes in crystallizable controlling units determine the temperature-memory of polymers}, series = {Journal of Materials Chemistry A, Materials for energy and sustainability}, volume = {16}, journal = {Journal of Materials Chemistry A, Materials for energy and sustainability}, number = {3}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2050-7488}, doi = {10.1039/c4ta06586g}, pages = {8284 -- 8293}, year = {2015}, abstract = {Temperature-memory polymers remember the temperature, where they were deformed recently, enabled by broad thermal transitions. In this study, we explored a series of crosslinked poly[ethylene-co-(vinyl acetate)] networks (cPEVAs) comprising crystallizable polyethylene (PE) controlling units exhibiting a pronounced temperature-memory effect (TME) between 16 and 99 °C related to a broad melting transition (∼100 °C). The nanostructural changes in such cPEVAs during programming and activation of the TME were analyzed via in situ X-ray scattering and specific annealing experiments. Different contributions to the mechanism of memorizing high or low deformation temperatures (Tdeform) were observed in cPEVA, which can be associated to the average PE crystal sizes. At high deformation temperatures (>50 °C), newly formed PE crystals, which are established during cooling when fixing the temporary shape, dominated the TME mechanism. In contrast, at low Tdeform (<50 °C), corresponding to a cold drawing scenario, the deformation led preferably to a disruption of existing large crystals into smaller ones, which then fix the temporary shape upon cooling. The observed mechanism of memorizing a deformation temperature might enable the prediction of the TME behavior and the knowledge based design of other TMPs with crystallizable controlling units.}, language = {en} } @phdthesis{Primus2015, author = {Primus, Philipp-Alexander}, title = {High resolution spectroscopy as a tool to unravel structure-reactivity relationships in Eu3+ doped ceria/ceria-zirconia based catalyst nanomaterials}, school = {Universit{\"a}t Potsdam}, pages = {89}, year = {2015}, language = {en} } @phdthesis{Adamla2015, author = {Adamla, Frauke}, title = {Polyglutamine- and aging-dependent aberrancies in transcription and translation}, school = {Universit{\"a}t Potsdam}, pages = {109}, year = {2015}, language = {en} } @phdthesis{Tetzner2014, author = {Tetzner, Julia}, title = {Stability and change in academic, social, and emotional development from early adolescence to young adulthood}, school = {Universit{\"a}t Potsdam}, pages = {191}, year = {2014}, language = {en} } @phdthesis{Alseekh2015, author = {Alseekh, Saleh}, title = {Identification and mode of inheritance of quantitative trait loci (QTL) for metabolite abundance in tomato}, school = {Universit{\"a}t Potsdam}, pages = {134}, year = {2015}, language = {en} } @phdthesis{AlSaedy2015, author = {Al-Saedy, Ammar Jaffar Muhesin}, title = {Normally solvable lagrangian boundary value problems}, school = {Universit{\"a}t Potsdam}, pages = {110}, year = {2015}, language = {en} } @phdthesis{Yuan2015, author = {Yuan, Jiayin}, title = {Poly(Ionic Liquid)s}, school = {Universit{\"a}t Potsdam}, pages = {300}, year = {2015}, language = {en} } @phdthesis{Tian2014, author = {Tian, Fang}, title = {Vegetation and environmental changes on millennial, centennial and decadal time-scales in central Mongolia and their driving forces}, school = {Universit{\"a}t Potsdam}, pages = {139}, year = {2014}, language = {en} } @phdthesis{Sauter2015, author = {Sauter, Tilman}, title = {Function by structure}, school = {Universit{\"a}t Potsdam}, pages = {166}, year = {2015}, language = {en} } @phdthesis{Mengel2015, author = {Mengel, Matthias}, title = {Forcing Earth's sea level}, school = {Universit{\"a}t Potsdam}, pages = {173}, year = {2015}, language = {en} } @phdthesis{Mueller2014, author = {M{\"u}ller, J{\"o}rg}, title = {Response of bryophyte diversity to land-use and management in forest and grassland habitats}, school = {Universit{\"a}t Potsdam}, pages = {133}, year = {2014}, language = {en} } @phdthesis{Brem2014, author = {Brem, Patrick}, title = {Compact objects in dense astrophysical environments}, school = {Universit{\"a}t Potsdam}, pages = {173}, year = {2014}, language = {en} } @phdthesis{Soja2014, author = {Soja, Aleksandra Maria}, title = {Transcriptomic and metabolomic analysis of Arabidopsis thaliana during abiotic stress}, pages = {134}, year = {2014}, language = {en} } @phdthesis{Sklodowski2015, author = {Sklodowski, Kamil}, title = {Regulation of plant potassium channels}, school = {Universit{\"a}t Potsdam}, pages = {115}, year = {2015}, language = {en} } @phdthesis{Zhao2015, author = {Zhao, Liming}, title = {Characterization genes involved in leaf development and senescence of arabidopsis}, school = {Universit{\"a}t Potsdam}, pages = {137}, year = {2015}, language = {en} } @phdthesis{Eggers2014, author = {Eggers, Ute}, title = {Environmental impacts on white stork (Ciconia ciconia) breeding success}, school = {Universit{\"a}t Potsdam}, pages = {164}, year = {2014}, language = {en} } @phdthesis{Schoenebeck2014, author = {Sch{\"o}nebeck, Maria}, title = {Behavioural, visual, and electrophysiological correlates of infant reasoning about others' intentional actions}, school = {Universit{\"a}t Potsdam}, pages = {158}, year = {2014}, language = {en} } @phdthesis{Lang2014, author = {Lang, Iris Scarlett}, title = {Fetal programming of growth and metabolism by maternal dietary composition}, pages = {99}, year = {2014}, language = {en} } @article{MondalBehrensMatthesetal.2015, author = {Mondal, Suvendu Sekhar and Behrens, Karsten and Matthes, Philipp R. and Sch{\"o}nfeld, Fabian and Nitsch, J{\"o}rn and Steffen, Andreas and Primus, Philipp-Alexander and Kumke, Michael Uwe and M{\"u}ller-Buschbaum, Klaus and Holdt, Hans-J{\"u}rgen}, title = {White light emission of IFP-1 by in situ co-doping of the MOF pore system with Eu3+ and Tb3+}, series = {Journal of materials chemistry : C, Materials for optical and electronic devices}, volume = {18}, journal = {Journal of materials chemistry : C, Materials for optical and electronic devices}, number = {3}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2050-7534}, doi = {10.1039/C4TC02919D}, pages = {4623 -- 4631}, year = {2015}, abstract = {Co-doping of the MOF 3∞[Zn(2-methylimidazolate-4-amide-5-imidate)] (IFP-1 = Imidazolate Framework Potsdam-1) with luminescent Eu3+ and Tb3+ ions presents an approach to utilize the porosity of the MOF for the intercalation of luminescence centers and for tuning of the chromaticity to the emission of white light of the quality of a three color emitter. Organic based fluorescence processes of the MOF backbone as well as metal based luminescence of the dopants are combined to one homogenous single source emitter while retaining the MOF's porosity. The lanthanide ions Eu3+ and Tb3+ were doped in situ into IFP-1 upon formation of the MOF by intercalation into the micropores of the growing framework without a structure directing effect. Furthermore, the color point is temperature sensitive, so that a cold white light with a higher blue content is observed at 77 K and a warmer white light at room temperature (RT) due to the reduction of the organic emission at higher temperatures. The study further illustrates the dependence of the amount of luminescent ions on porosity and sorption properties of the MOF and proves the intercalation of luminescence centers into the pore system by low-temperature site selective photoluminescence spectroscopy, SEM and EDX. It also covers an investigation of the border of homogenous uptake within the MOF pores and the formation of secondary phases of lanthanide formates on the surface of the MOF. Crossing the border from a homogenous co-doping to a two-phase composite system can be beneficially used to adjust the character and warmth of the white light. This study also describes two-color emitters of the formula Ln@IFP-1a-d (Ln: Eu, Tb) by doping with just one lanthanide Eu3+ or Tb3+.}, language = {en} } @article{MegowRoehrSchmidtamBuschetal.2015, author = {Megow, J{\"o}rg and R{\"o}hr, Merle I. S. and Schmidt am Busch, Marcel and Renger, Thomas and Mitrić, Roland and Kirstein, Stefan and Rabe, J{\"u}rgen P. and May, Volkhard}, title = {Site-dependence of van der Waals interaction explains exciton spectra of double-walled tubular J-aggregates}, series = {Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies}, volume = {17}, journal = {Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies}, number = {10}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9084}, doi = {10.1039/c4cp05945j}, pages = {6741 -- 6747}, year = {2015}, abstract = {The simulation of the optical properties of supramolecular aggregates requires the development of methods, which are able to treat a large number of coupled chromophores interacting with the environment. Since it is currently not possible to treat large systems by quantum chemistry, the Frenkel exciton model is a valuable alternative. In this work we show how the Frenkel exciton model can be extended in order to explain the excitonic spectra of a specific double-walled tubular dye aggregate explicitly taking into account dispersive energy shifts of ground and excited states due to van der Waals interaction with all surrounding molecules. The experimentally observed splitting is well explained by the site-dependent energy shift of molecules placed at the inner or outer side of the double-walled tube, respectively. Therefore we can conclude that inclusion of the site-dependent dispersive effect in the theoretical description of optical properties of nanoscaled dye aggregates is mandatory.}, language = {en} } @article{CroneAschnerSchwerdtleetal.2015, author = {Crone, Barbara and Aschner, Michael A. and Schwerdtle, Tanja and Karst, Uwe and Bornhorst, Julia}, title = {Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS}, series = {Metallomics}, volume = {2015}, journal = {Metallomics}, number = {7}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1756-591X}, doi = {10.1039/c5mt00096c}, pages = {1189 -- 1195}, year = {2015}, abstract = {cis-Diamminedichloroplatinum(II) (Cisplatin) is one of the most important and frequently used cytostatic drugs for the treatment of various solid tumors. Herein, a laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) method incorporating a fast and simple sample preparation protocol was developed for the elemental mapping of Cisplatin in the model organism Caenorhabditis elegans (C. elegans). The method allows imaging of the spatially-resolved elemental distribution of platinum in the whole organism with respect to the anatomic structure in L4 stage worms at a lateral resolution of 5 μm. In addition, a dose- and time-dependent Cisplatin uptake was corroborated quantitatively by a total reflection X-ray fluorescence spectroscopy (TXRF) method, and the elemental mapping indicated that Cisplatin is located in the intestine and in the head of the worms. Better understanding of the distribution of Cisplatin in this well-established model organism will be instrumental in deciphering Cisplatin toxicity and pharmacokinetics. Since the cytostatic effect of Cisplatin is based on binding the DNA by forming intra- and interstrand crosslinks, the response of poly(ADP-ribose)metabolism enzyme 1 (pme-1) deletion mutants to Cisplatin was also examined. Loss of pme-1, which is the C. elegans ortholog of human poly(ADP-ribose) polymerase 1 (PARP-1) led to disturbed DNA damage response. With respect to survival and brood size, pme-1 deletion mutants were more sensitive to Cisplatin as compared to wildtype worms, while Cisplatin uptake was indistinguishable.}, language = {en} } @phdthesis{Beinrucker2015, author = {Beinrucker, Andre}, title = {Variable selection in high dimensional data analysis with applications}, school = {Universit{\"a}t Potsdam}, pages = {VII, 107}, year = {2015}, language = {en} } @article{PietraLangGrebe2015, author = {Pietra, Stefano and Lang, Patricia and Grebe, Markus}, title = {SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana}, series = {Physiologia Plantarum}, volume = {153}, journal = {Physiologia Plantarum}, number = {3}, doi = {DOI: 10.1111/ppl.12257}, pages = {440 -- 453}, year = {2015}, abstract = {Patterned differentiation of distinct cell types is essential for the development of multicellular organisms. The root epidermis of Arabidopsis thaliana is composed of alternating files of root hair and non-hair cells and represents a model system for studying the control of cell-fate acquisition. Epidermal cell fate is regulated by a network of genes that translate positional information from the underlying cortical cell layer into a specific pattern of differentiated cells. While much is known about the genes of this network, new players continue to be discovered. Here we show that the SABRE (SAB) gene, known to mediate microtubule organization, anisotropic cell growth and planar polarity, has an effect on root epidermal hair cell patterning. Loss of SAB function results in ectopic root hair formation and destabilizes the expression of cell fate and differentiation markers in the root epidermis, including expression of the WEREWOLF (WER) and GLABRA2 (GL2) genes. Double mutant analysis reveal that wer and caprice (cpc) mutants, defective in core components of the epidermal patterning pathway, genetically interact with sab. This suggests that SAB may act on epidermal patterning upstream of WER and CPC. Hence, we provide evidence for a role of SAB in root epidermal patterning by affecting cell-fate stabilization. Our work opens the door for future studies addressing SAB-dependent functions of the cytoskeleton during root epidermal patterning.}, language = {en} } @article{KieferClaesNzayisengaetal.2015, author = {Kiefer, Christian S. and Claes, Andrea R. and Nzayisenga, Jean-Claude and Pietra, Stefano and Stanislas, Thomas and Ikeda, Yoshihisa and Grebe, Markus}, title = {Arabidopsis AIP1-2 restricted by WER-mediated patterning modulates planar polarity}, series = {Development}, journal = {Development}, number = {142}, doi = {doi: 10.1242/dev.111013}, pages = {151 -- 161}, year = {2015}, abstract = {The coordination of cell polarity within the plane of the tissue layer (planar polarity) is crucial for the development of diverse multicellular organisms. Small Rac/Rho-family GTPases and the actin cytoskeleton contribute to planar polarity formation at sites of polarity establishment in animals and plants. Yet, upstream pathways coordinating planar polarity differ strikingly between kingdoms. In the root of Arabidopsis thaliana, a concentration gradient of the phytohormone auxin coordinates polar recruitment of Rho-of-plant (ROP) to sites of polar epidermal hair initiation. However, little is known about cytoskeletal components and interactions that contribute to this planar polarity or about their relation to the patterning machinery. Here, we show that ACTIN7 (ACT7) represents a main actin isoform required for planar polarity of root hair positioning, interacting with the negative modulator ACTIN-INTERACTING PROTEIN1-2 (AIP1-2). ACT7, AIP1-2 and their genetic interaction are required for coordinated planar polarity of ROP downstream of ethylene signalling. Strikingly, AIP1-2 displays hair cell file-enriched expression, restricted by WEREWOLF (WER)-dependent patterning and modified by ethylene and auxin action. Hence, our findings reveal AIP1-2, expressed under control of the WER-dependent patterning machinery and the ethylene signalling pathway, as a modulator of actin-mediated planar polarity.}, language = {en} } @article{MetzlerBauerRasmussenetal.2015, author = {Metzler, Ralf and Bauer, Maximilian and Rasmussen, Emil S. and Lomholt, Michael A.}, title = {Real sequence effects on the search dynamics of transcription factors on DNA}, series = {Scientific Reports}, volume = {5}, journal = {Scientific Reports}, number = {10072}, publisher = {Nature Publishing Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep10072}, year = {2015}, abstract = {Recent experiments show that transcription factors (TFs) indeed use the facilitated diffusion mechanism to locate their target sequences on DNA in living bacteria cells: TFs alternate between sliding motion along DNA and relocation events through the cytoplasm. From simulations and theoretical analysis we study the TF-sliding motion for a large section of the DNA-sequence of a common E. coli strain, based on the two-state TF-model with a fast-sliding search state and a recognition state enabling target detection. For the probability to detect the target before dissociating from DNA the TF-search times self-consistently depend heavily on whether or not an auxiliary operator (an accessible sequence similar to the main operator) is present in the genome section. Importantly, within our model the extent to which the interconversion rates between search and recognition states depend on the underlying nucleotide sequence is varied. A moderate dependence maximises the capability to distinguish between the main operator and similar sequences. Moreover, these auxiliary operators serve as starting points for DNA looping with the main operator, yielding a spectrum of target detection times spanning several orders of magnitude. Auxiliary operators are shown to act as funnels facilitating target detection by TFs.}, language = {en} } @phdthesis{Gassmoeller2014, author = {Gaßm{\"o}ller, Ren{\´e}}, title = {The interaction of subducted slabs and plume generation zones in geodynamic models}, school = {Universit{\"a}t Potsdam}, pages = {158}, year = {2014}, language = {en} } @article{HaendlerKlieglAdani2015, author = {Haendler, Yair and Kliegl, Reinhold and Adani, Flavia}, title = {Discourse accessibility constraints in children´s processing of object relative clauses}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {860}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00860}, year = {2015}, abstract = {Children's poor performance on object relative clauses has been explained in terms of intervention locality. This approach predicts that object relatives with a full DP head and an embedded pronominal subject are easier than object relatives in which both the head noun and the embedded subject are full DPs. This prediction is shared by other accounts formulated to explain processing mechanisms. We conducted a visual-world study designed to test the off-line comprehension and on-line processing of object relatives in German-speaking 5-year-olds. Children were tested on three types of object relatives, all having a full DP head noun and differing with respect to the type of nominal phrase that appeared in the embedded subject position: another full DP, a 1st- or a 3rd-person pronoun. Grammatical skills and memory capacity were also assessed in order to see whether and how they affect children's performance. Most accurately processed were object relatives with 1st-person pronoun, independently of children's language and memory skills. Performance on object relatives with two full DPs was overall more accurate than on object relatives with 3rd-person pronoun. In the former condition, children with stronger grammatical skills accurately processed the structure and their memory abilities determined how fast they were; in the latter condition, children only processed accurately the structure if they were strong both in their grammatical skills and in their memory capacity. The results are discussed in the light of accounts that predict different pronoun effects like the ones we find, which depend on the referential properties of the pronouns. We then discuss which role language and memory abilities might have in processing object relatives with various embedded nominal phrases.}, language = {en} } @article{HaeusslerBader2015, author = {H{\"a}ussler, Jana and Bader, Markus}, title = {An interference account of the missing-VP effect}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {766}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00766}, year = {2015}, abstract = {Sentences with doubly center-embedded relative clauses in which a verb phrase (VP) is missing are sometimes perceived as grammatical, thus giving rise to an illusion of grammaticality. In this paper, we provide a new account of why missing-VP sentences, which are both complex and ungrammatical, lead to an illusion of grammaticality, the so-called missing-VP effect. We propose that the missing-VP effect in particular, and processing difficulties with multiply center-embedded clauses more generally, are best understood as resulting from interference during cue-based retrieval. When processing a sentence with double center-embedding, a retrieval error due to interference can cause the verb of an embedded clause to be erroneously attached into a higher clause. This can lead to an illusion of grammaticality in the case of missing-VP sentences and to processing complexity in the case of complete sentences with double center-embedding. Evidence for an interference account of the missing-VP effect comes from experiments that have investigated the missing-VP effect in German using a speeded grammaticality judgments procedure. We review this evidence and then present two new experiments that show that the missing-VP effect can be found in German also with less restricting procedures. One experiment was a questionnaire study which required grammaticality judgments from participants without imposing any time constraints. The second experiment used a self-paced reading procedure and did not require any judgments. Both experiments confirm the prior findings of missing-VP effects in German and also show that the missing-VP effect is subject to a primacy effect as known from the memory literature. Based on this evidence, we argue that an account of missing-VP effects in terms of interference during cue-based retrieval is superior to accounts in terms of limited memory resources or in terms of experience with embedded structures.}, language = {en} } @article{FelserPattersonCunnings2015, author = {Felser, Claudia and Patterson, Clare and Cunnings, Ian}, title = {Structural constraints on pronoun binding and coreference: Evidence from eye movements during reading}, series = {Frontiers in psychology}, volume = {6}, journal = {Frontiers in psychology}, number = {840}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2015.00840}, year = {2015}, abstract = {A number of recent studies have investigated how syntactic and non-syntactic constraints combine to cue memory retrieval during anaphora resolution. In this paper we investigate how syntactic constraints and gender congruence interact to guide memory retrieval during the resolution of subject pronouns. Subject pronouns are always technically ambiguous, and the application of syntactic constraints on their interpretation depends on properties of the antecedent that is to be retrieved. While pronouns can freely corefer with non-quantified referential antecedents, linking a pronoun to a quantified antecedent is only possible in certain syntactic configurations via variable binding. We report the results from a judgment task and three online reading comprehension experiments investigating pronoun resolution with quantified and non-quantified antecedents. Results from both the judgment task and participants' eye movements during reading indicate that comprehenders freely allow pronouns to corefer with non-quantified antecedents, but that retrieval of quantified antecedents is restricted to specific syntactic environments. We interpret our findings as indicating that syntactic constraints constitute highly weighted cues to memory retrieval during anaphora resolution.}, language = {en} } @article{MetzlerCherstvyChechkinetal.2015, author = {Metzler, Ralf and Cherstvy, Andrey G. and Chechkin, Aleksei V. and Bodrova, Anna S.}, title = {Ultraslow scaled Brownian motion}, series = {New journal of physics : the open-access journal for physics}, volume = {17}, journal = {New journal of physics : the open-access journal for physics}, number = {063038}, publisher = {Dt. Physikalische Ges., IOP}, address = {Bad Honnef, London}, issn = {1367-2630}, doi = {10.1088/1367-2630/17/6/063038}, year = {2015}, abstract = {We define and study in detail utraslow scaled Brownian motion (USBM) characterized by a time dependent diffusion coefficient of the form . For unconfined motion the mean squared displacement (MSD) of USBM exhibits an ultraslow, logarithmic growth as function of time, in contrast to the conventional scaled Brownian motion. In a harmonic potential the MSD of USBM does not saturate but asymptotically decays inverse-proportionally to time, reflecting the highly non-stationary character of the process. We show that the process is weakly non-ergodic in the sense that the time averaged MSD does not converge to the regular MSD even at long times, and for unconfined motion combines a linear lag time dependence with a logarithmic term. The weakly non-ergodic behaviour is quantified in terms of the ergodicity breaking parameter. The USBM process is also shown to be ageing: observables of the system depend on the time gap between initiation of the test particle and start of the measurement of its motion. Our analytical results are shown to agree excellently with extensive computer simulations.}, language = {en} } @phdthesis{Mueller2015, author = {M{\"u}ller, Eva Nora}, title = {The ecohydrological transfers, interactions and degradation arising from high-intensity storm events}, school = {Universit{\"a}t Potsdam}, pages = {224}, year = {2015}, language = {en} } @phdthesis{Pinchasik2015, author = {Pinchasik, Bat-El Shani}, title = {Manipulaton of Microbubbles Inspired by Bubble Use in Nature}, school = {Universit{\"a}t Potsdam}, pages = {123}, year = {2015}, language = {en} } @phdthesis{Zhou2014, author = {Zhou, Xu}, title = {Atmospheric interactions with land surface in the arctic based on regional climate model solutions}, pages = {143}, year = {2014}, language = {en} } @phdthesis{HoffmannRobbiani2015, author = {Hoffmann Robbiani, Sandra}, title = {But 7 is yellower than Q, isn't it?}, publisher = {Hoffmann}, address = {Darmstadt}, isbn = {978-3-946069-01-0}, pages = {393}, year = {2015}, language = {en} } @phdthesis{Prill2015, author = {Prill, Sebastian}, title = {Real-Time in vitro toxicity monotoring in a microfluidic bioreactor for drug and chemical safety assessment}, pages = {119}, year = {2015}, language = {en} } @phdthesis{Kamprath2014, author = {Kamprath, Martin}, title = {A microfoundations perspectives on fresight and business models}, pages = {224}, year = {2014}, language = {en} } @phdthesis{Kocyan2014, author = {Kocyan, Alexander}, title = {Evolution within the speciose plant group of asparagales}, year = {2014}, language = {en} } @phdthesis{Gericke2014, author = {Gericke, Lutz}, title = {Tele-Board - Supporting and analyzing creative collaboration in synchronous and asynchronous scenario}, pages = {186}, year = {2014}, language = {en} }