@article{CastelliniPaltrinieriManca2015,
  author    = {Castellini, Alberto and Paltrinieri, Daniele and Manca, Vincenzo},
  title     = {MP-GeneticSynth: inferring biological network regulations from time series},
  series = {Bioinformatics},
  volume    = {31},
  journal   = {Bioinformatics},
  number    = {5},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {1367-4803},
  doi       = {10.1093/bioinformatics/btu694},
  pages     = {785 -- 787},
  year      = {2015},
  abstract  = {MP-GeneticSynth is a Java tool for discovering the logic and regulation mechanisms responsible for observed biological dynamics in terms of finite difference recurrent equations. The software makes use of: (i) metabolic P systems as a modeling framework, (ii) an evolutionary approach to discover flux regulation functions as linear combinations of given primitive functions, (iii) a suitable reformulation of the least squares method to estimate function parameters considering simultaneously all the reactions involved in complex dynamics. The tool is available as a plugin for the virtual laboratory MetaPlab. It has graphical and interactive interfaces for data preparation, a priori knowledge integration, and flux regulator analysis.},
  language  = {en}
}