@article{KrokeSchmidtAminietal.2022,
  author    = {Kroke, Anja and Schmidt, Annemarie and Amini, Anna M. and Kalotai, Nicole and Lehmann, Andreas and Haardt, Julia and Bauer, J{\"u}rgen M. and Bischoff-Ferrari, Heike A. and Boeing, Heiner and Egert, Sarah and Ellinger, Sabine and K{\"u}hn, Tilman and Louis, Sandrine and Lorkowski, Stefan and Nimptsch, Katharina and Remer, Thomas and Schulze, Matthias B. and Siener, Roswitha and Stangl, Gabriele and Volkert, Dorothee and Zittermann, Armin and Buyken, Anette E. and Watzl, Bernhard and Schwingshackl, Lukas},
  title     = {Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society},
  series = {European journal of nutrition},
  volume    = {61},
  journal   = {European journal of nutrition},
  number    = {4},
  publisher = {Springer Nature},
  address   = {Heidelberg},
  organization    = {German Nutr Soc},
  issn      = {1436-6207},
  doi       = {10.1007/s00394-021-02789-5},
  pages     = {2091 -- 2101},
  year      = {2022},
  abstract  = {Purpose: The present work aimed to delineate (i) a revised protocol according to recent methodological developments in evidence generation, to (ii) describe its interpretation, the assessment of the overall certainty of evidence and to (iii) outline an Evidence to Decision framework for deriving an evidence-based guideline on quantitative and qualitative aspects of dietary protein intake. Methods A methodological protocol to systematically investigate the association between dietary protein intake and several health outcomes and for deriving dietary protein intake recommendations for the primary prevention of various non-communicable diseases in the general adult population was developed. Results The developed methodological protocol relies on umbrella reviews including systematic reviews with or without meta-analyses. Systematic literature searches in three databases will be performed for each health-related outcome. The methodological quality of all selected systematic reviews will be evaluated using a modified version of AMSTAR 2, and the outcome-specific certainty of evidence for systematic reviews with or without meta-analysis will be assessed with NutriGrade. The general outline of the Evidence to Decision framework foresees that recommendations in the derived guideline will be given based on the overall certainty of evidence as well as on additional criteria such as sustainability. Conclusion The methodological protocol permits a systematic evaluation of published systematic reviews on dietary protein intake and its association with selected health-related outcomes. An Evidence to Decision framework will be the basis for the overall conclusions and the resulting recommendations for dietary protein intake.},
  language  = {en}
}
@article{AndersKhalatyanQueirozetal.2022,
  author    = {Anders, Friedrich and Khalatyan, Arman and Queiroz, Anna B. A. and Chiappini, Cristina and Ard{\`e}vol, Judith and Casamiquela, Laia and Figueras, Francesca and Jim{\´e}nez-Arranz, {\´O}scar and Jordi, Carme and Monguio, Maria and Romero-G{\´o}mez, Merce and Altamirano, Diego and Antoja, Teresa and Assaad, R. and Cantat-Gaudin, Tristan and Castro-Ginard, Alfred and Enke, Harry and Girardi, L{\´e}o and Guiglion, Guillaume and Khan, Saniya and Luri, Xavier and Miglio, Andrea and Minchev, Ivan and Ramos, Pau and Santiago, Basillio Xavier and Steinmetz, Matthias},
  title     = {Photo-astrometric distances, extinctions, and astrophysical parameters for Gaia EDR3 stars brighter than G=18.5},
  series = {Astronomy and astrophysics},
  volume    = {658},
  journal   = {Astronomy and astrophysics},
  publisher = {EDP Sciences},
  address   = {Les Ulis},
  issn      = {0004-6361},
  doi       = {10.1051/0004-6361/202142369},
  pages     = {27},
  year      = {2022},
  abstract  = {We present a catalogue of 362 million stellar parameters, distances, and extinctions derived from Gaia's Early Data Release (EDR3) cross-matched with the photometric catalogues of Pan-STARRS1, SkyMapper, 2MASS, and All WISE. The higher precision of the Gaia EDR3 data, combined with the broad wavelength coverage of the additional photometric surveys and the new stellar-density priors of the StarHorse code, allows us to substantially improve the accuracy and precision over previous photo-astrometric stellar-parameter estimates. At magnitude G = 14 (17), our typical precisions amount to 3\% (15\%) in distance, 0.13 mag (0.15 mag) in V-band extinction, and 140 K (180 K) in effective temperature. Our results are validated by comparisons with open clusters, as well as with asteroseismic and spectroscopic measurements, indicating systematic errors smaller than the nominal uncertainties for the vast majority of objects. We also provide distance- and extinction-corrected colour-magnitude diagrams, extinction maps, and extensive stellar density maps that reveal detailed substructures in the Milky Way and beyond. The new density maps now probe a much greater volume, extending to regions beyond the Galactic bar and to Local Group galaxies, with a larger total number density. We publish our results through an ADQL query interface (gaia . aip . de) as well as via tables containing approximations of the full posterior distributions. Our multi-wavelength approach and the deep magnitude limit render our results useful also beyond the next Gaia release, DR3.},
  language  = {en}
}
@article{PohankovaHlavinkaKersebaumetal.2022,
  author    = {Pohankov{\´a}, Eva and Hlavinka, Petr and Kersebaum, Kurt-Christian and Rodr{\´i}guez, Alfredo and Balek, Jan and Bednař{\´i}k, Martin and Dubrovsk{\´y}, Martin and Gobin, Anne and Hoogenboom, Gerrit and Moriondo, Marco and Nendel, Claas and Olesen, J{\o}rgen E. E. and R{\"o}tter, Reimund Paul and Ruiz-Ramos, Margarita and Shelia, Vakhtang and Stella, Tommaso and Hoffmann, Munir Paul and Tak{\´a}č, Jozef and Eitzinger, Josef and Dibari, Camilla and Ferrise, Roberto and Bl{\´a}hov{\´a}, Monika and Trnka, Miroslav},
  title     = {Expected effects of climate change on the production and water use of crop rotation management reproduced by crop model ensemble for Czech Republic sites},
  series = {European journal of agronomy},
  volume    = {134},
  journal   = {European journal of agronomy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1161-0301},
  doi       = {10.1016/j.eja.2021.126446},
  pages     = {27},
  year      = {2022},
  abstract  = {Crop rotation, fertilization and residue management affect the water balance and crop production and can lead to different sensitivities to climate change. To assess the impacts of climate change on crop rotations (CRs), the crop model ensemble (APSIM,AQUACROP, CROPSYST, DAISY, DSSAT, HERMES, MONICA) was used. The yields and water balance of two CRs with the same set of crops (winter wheat, silage maize, spring barley and winter rape) in a continuous transient run from 1961 to 2080 were simulated. CR1 was without cover crops and without manure application. Straw after the harvest was exported from the fields. CR2 included cover crops, manure application and crop residue retention left on field. Simulations were performed using two soil types (Chernozem, Cambisol) within three sites in the Czech Republic, which represent temperature and precipitation gradients for crops in Central Europe. For the description of future climatic conditions, seven climate scenarios were used. Six of them had increasing CO \& nbsp;concentrations according RCP 8.5, one had no CO2 increase in the future. The output of an ensemble expected higher productivity by 0.82 t/ha/year and 2.04 t/ha/year for yields and aboveground biomass in the future (2051-2080). However, if the direct effect of a CO2 increase is not considered, the average yields for lowlands will be lower. Compared to CR1, CR2 showed higher average yields of 1.26 t/ha/year for current climatic conditions and 1.41 t/ha/year for future climatic conditions. For the majority of climate change scenarios, the crop model ensemble agrees on the projected yield increase in C3 crops in the future for CR2 but not for CR1. Higher agreement for future yield increases was found for Chernozem, while for Cambisol, lower yields under dry climate scenarios are expected. For silage maize, changes in simulated yields depend on locality. If the same hybrid will be used in the future, then yield reductions should be expected within lower altitudes. The results indicate the potential for higher biomass production from cover crops, but CR2 is associated with almost 120 mm higher evapotranspiration compared to that of CR1 over a 5-year cycle for lowland stations in the future, which in the case of the rainfed agriculture could affect the long-term soil water balance. This could affect groundwater replenishment, especially for locations with fine textured soils, although the findings of this study highlight the potential for the soil water-holding capacity to buffer against the adverse weather conditions.},
  language  = {en}
}
@article{FoerstnerTschornReinosoSchilleretal.2022,
  author    = {F{\"o}rstner, Bernd R. and Tschorn, Mira and Reinoso-Schiller, Nicolas and Maričić, Lea Mascarell and R{\"o}cher, Erik and Kalman, Janos L. and Stroth, Sanna and Mayer, Annalina V. and Schwarz, Kristina and Kaiser, Anna and Pfennig, Andrea and Manook, Andr{\´e} and Ising, Marcus and Heinig, Ingmar and Pittig, Andre and Heinz, Andreas and Mathiak, Klaus and Schulze, Thomas G. and Schneider, Frank and Kamp-Becker, Inge and Meyer-Lindenberg, Andreas and Padberg, Frank and Banaschewski, Tobias and Bauer, Michael and Rupprecht, Rainer and Wittchen, Hans-Ulrich and Rapp, Michael A.},
  title     = {Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis},
  series = {European archives of psychiatry and clinical neuroscience},
  volume    = {273},
  journal   = {European archives of psychiatry and clinical neuroscience},
  number    = {3},
  publisher = {Springer Nature},
  address   = {Heidelberg},
  issn      = {0940-1334},
  doi       = {10.1007/s00406-022-01440-6},
  pages     = {527 -- 539},
  year      = {2022},
  abstract  = {This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts across DSM/ICD-10 disorder criteria categories. One thousand four hundred and thirty one participants (42.1\% suffering from anxiety/fear-related, 18.2\% from depressive, 7.9\% from schizophrenia spectrum, 7.5\% from bipolar, 3.4\% from autism spectrum, 2.2\% from other disorders, 18.4\% healthy controls, and 0.2\% with no diagnosis specified) recruited in studies within the German research network for mental disorders for the Phenotypic, Diagnostic and Clinical Domain Assessment Network Germany (PD-CAN) were examined with a Mini-RDoC-Assessment including behavioral and self-report measures. The respective data was analyzed with confirmatory factor analysis (CFA) to delineate the underlying latent RDoC-structure. A revised four-factor model reflecting the core domains positive and negative valence systems as well as cognitive systems and social processes showed a good fit across this sample and showed significantly better fit compared to a one factor solution. The connections between the domains PVS, NVS and SP could be substantiated, indicating a universal latent structure spanning across known nosological entities. This study is the first to give an impression on the latent structure and intercorrelations between four core Research Domain Criteria in a transnosological sample. We emphasize the possibility of using already existing and well validated self-report and behavioral measurements to capture aspects of the latent structure informed by the RDoC matrix.},
  language  = {en}
}
@article{RuiperezValienteStaubitzJenneretal.2022,
  author    = {Ruip{\´e}rez-Valiente, Jos{\´e} A. and Staubitz, Thomas and Jenner, Matt and Halawa, Sherif and Zhang, Jiayin and Despujol, Ignacio and Maldonado-Mahauad, Jorge and Montoro, German and Peffer, Melanie and Rohloff, Tobias and Lane, Jenny and Turro, Carlos and Li, Xitong and P{\´e}rez-Sanagust{\´i}n, Mar and Reich, Justin},
  title     = {Large scale analytics of global and regional MOOC providers: Differences in learners' demographics, preferences, and perceptions},
  series = {Computers \& education},
  volume    = {180},
  journal   = {Computers \& education},
  publisher = {Elsevier},
  address   = {Oxford},
  issn      = {0360-1315},
  doi       = {10.1016/j.compedu.2021.104426},
  pages     = {17},
  year      = {2022},
  abstract  = {Massive Open Online Courses (MOOCs) remarkably attracted global media attention, but the spotlight has been concentrated on a handful of English-language providers. While Coursera, edX, Udacity, and FutureLearn received most of the attention and scrutiny, an entirely new ecosystem of local MOOC providers was growing in parallel. This ecosystem is harder to study than the major players: they are spread around the world, have less staff devoted to maintaining research data, and operate in multiple languages with university and corporate regional partners. To better understand how online learning opportunities are expanding through this regional MOOC ecosystem, we created a research partnership among 15 different MOOC providers from nine countries. We gathered data from over eight million learners in six thousand MOOCs, and we conducted a large-scale survey with more than 10 thousand participants. From our analysis, we argue that these regional providers may be better positioned to meet the goals of expanding access to higher education in their regions than the better-known global providers. To make this claim we highlight three trends: first, regional providers attract a larger local population with more inclusive demographic profiles; second, students predominantly choose their courses based on topical interest, and regional providers do a better job at catering to those needs; and third, many students feel more at ease learning from institutions they already know and have references from. Our work raises the importance of local education in the global MOOC ecosystem, while calling for additional research and conversations across the diversity of MOOC providers.},
  language  = {en}
}
@article{KelesMallonnKitzmannetal.2022,
  author    = {Keles, Engin and Mallonn, Matthias and Kitzmann, Daniel and Poppenh{\"a}ger, Katja and Hoeijmakers, H. Jens and Ilyin, Ilya and Alexoudi, Xanthippi and Carroll, Thorsten A. and Alvarado-Gomez, Julian and Ketzer, Laura and Bonomo, Aldo S. and Borsa, Francesco and Gaudi, B. Scott and Henning, Thomas and Malavolta, Luca and Molaverdikhani, Karan and Nascimbeni, Valerio and Patience, Jennifer and Pino, Lorenzo and Scandariato, Gaetano and Schlawin, Everett and Shkolnik, Evgenya and Sicilia, Daniela and Sozzetti, Alessandro and Foster, Mary G. and Veillet, Christian and Wang, Ji and Yan, Fei and Strassmeier, Klaus G.},
  title     = {The PEPSI exoplanet transit survey (PETS) I: Investigating the presence of a silicate atmosphere on the super-earth 55 Cnc e},
  series = {Monthly notices of the Royal Astronomical Society},
  volume    = {513},
  journal   = {Monthly notices of the Royal Astronomical Society},
  number    = {1},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0035-8711},
  doi       = {10.1093/mnras/stac810},
  pages     = {1544 -- 1556},
  year      = {2022},
  abstract  = {The study of exoplanets and especially their atmospheres can reveal key insights on their evolution by identifying specific atmospheric species. For such atmospheric investigations, high-resolution transmission spectroscopy has shown great success, especially for Jupiter-type planets. Towards the atmospheric characterization of smaller planets, the super-Earth exoplanet 55 Cnc e is one of the most promising terrestrial exoplanets studied to date. Here, we present a high-resolution spectroscopic transit observation of this planet, acquired with the PEPSI instrument at the Large Binocular Telescope. Assuming the presence of Earth-like crust species on the surface of 55 Cnc e, from which a possible silicate-vapor atmosphere could have originated, we search in its transmission spectrum for absorption of various atomic and ionized species such as Fe , Fe (+), Ca , Ca (+), Mg, and K , among others. Not finding absorption for any of the investigated species, we are able to set absorption limits with a median value of 1.9 x R-P. In conclusion, we do not find evidence of a widely extended silicate envelope on this super-Earth reaching several planetary radii.},
  language  = {en}
}
@article{WangHeWangetal.2022,
  author    = {Wang, Enli and He, Di and Wang, Jing and Lilley, Julianne M. and Christy, Brendan and Hoffmann, Munir P. and O'Leary, Garry and Hatfield, Jerry L. and Ledda, Luigi and Deligios, Paola A. and Grant, Brian and Jing, Qi and Nendel, Claas and Kage, Henning and Qian, Budong and Rezaei, Ehsan Eyshi and Smith, Ward and Weymann, Wiebke and Ewert, Frank},
  title     = {How reliable are current crop models for simulating growth and seed yield of canola across global sites and under future climate change?},
  series = {Climatic change},
  volume    = {172},
  journal   = {Climatic change},
  number    = {1-2},
  publisher = {Springer Nature},
  address   = {Dordrecht},
  issn      = {0165-0009},
  doi       = {10.1007/s10584-022-03375-2},
  pages     = {22},
  year      = {2022},
  abstract  = {To better understand how climate change might influence global canola production, scientists from six countries have completed the first inter-comparison of eight crop models for simulating growth and seed yield of canola, based on experimental data from six sites across five countries. A sensitivity analysis was conducted with a combination of five levels of atmospheric CO2 concentrations, seven temperature changes, five precipitation changes, together with five nitrogen application rates. Our results were in several aspects different from those of previous model inter-comparison studies for wheat, maize, rice, and potato crops. A partial model calibration only on phenology led to very poor simulation of aboveground biomass and seed yield of canola, even from the ensemble median or mean. A full calibration with additional data of leaf area index, biomass, and yield from one treatment at each site reduced simulation error of seed yield from 43.8 to 18.0\%, but the uncertainty in simulation results remained large. Such calibration (with data from one treatment) was not able to constrain model parameters to reduce simulation uncertainty across the wide range of environments. Using a multi-model ensemble mean or median reduced the uncertainty of yield simulations, but the simulation error remained much larger than observation errors, indicating no guarantee that the ensemble mean/median would predict the correct responses. Using multi-model ensemble median, canola yield was projected to decline with rising temperature (2.5-5.7\% per degrees C), but to increase with increasing CO2 concentration (4.6-8.3\% per 100-ppm), rainfall (2.1-6.1\% per 10\% increase), and nitrogen rates (1.3-6.0\% per 10\% increase) depending on locations. Due to the large uncertainty, these results need to be treated with caution. We further discuss the need to collect new data to improve modelling of several key physiological processes of canola for increased confidence in future climate impact assessments.},
  language  = {en}
}
@article{KramerBouriaudFeindtetal.2022,
  author    = {Kramer, Koen and Bouriaud, Laura and Feindt, Peter H. and van Wassenaer, Lan and Glanemann, Nicole and Hanewinkel, Marc and van der Heide, Martijn and Hengeveld, Geerten M. and Hoogstra, Marjanke and Ingram, Verina and Levermann, Anders and Lindner, Marcus and M{\´a}ty{\´a}s, Csaba and Mohren, Frits and Muys, Bart and Nabuurs, Gert-Jan and Palahi, Marc and Polman, Nico and Reyer, Christopher P. O. and Schulze, Ernst-Detlef and Seidl, Rupert and de Vries, Wim and Werners, Saskia E. and Winkel, Georg and Yousefpour, Rasoul},
  title     = {Perspective Roadmap to develop a stress test for forest ecosystem services supply},
  series = {One Earth},
  volume    = {5},
  journal   = {One Earth},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2590-3330},
  doi       = {10.1016/j.oneear.2021.12.009},
  pages     = {25 -- 34},
  year      = {2022},
  abstract  = {Forests play a key role in a bio-based economy by providing renewable materials, mitigating climate change, and accommodating biodiversity. However, forests experience massive increases in stresses in their ecological and socioeconomic environments, threatening forest ecosystem services supply. Alleviating those stresses is hampered by conflicting and disconnected governance arrangements, competing interests and claims, and rapid changes in technology and social demands. Identifying which stresses threaten forest ecosystem services supply and which factors hamper their alleviation requires stakeholders' perceptions. Stakeholder-oriented stress tests for the supply of forest ecosystem services are therefore necessary but are not yet available. This perspective presents a roadmap to develop a stress test tailored to multiple stakeholders' needs and demands across spatial scales. We provide the Cascade and Resilience Rosetta, with accompanying performance- and resilience indicators, as tools to facilitate development of the stress test. The application of the stress test will facilitate the transition toward a bio-based economy in which healthy and diverse forests provide sustainable and resilient ecosystem services.},
  language  = {en}
}
@article{DamleSparreRichteretal.2022,
  author    = {Damle, Mitali and Sparre, Martin and Richter, Philipp and Hani, Maan H. and Nuza, Sebasti{\´a}n E. and Pfrommer, Christoph and Grand, Robert J. J. and Hoffman, Yehuda and Libeskind, Noam and Sorce, Jenny G. and Steinmetz, Matthias and Tempel, Elmo and Vogelsberger, Mark and Wang, Peng},
  title     = {Cold and hot gas distribution around the Milky-Way-M31 system in the HESTIA simulations},
  series = {Monthly notices of the Royal Astronomical Society},
  volume    = {512},
  journal   = {Monthly notices of the Royal Astronomical Society},
  number    = {3},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0035-8711},
  doi       = {10.1093/mnras/stac663},
  pages     = {3717 -- 3737},
  year      = {2022},
  abstract  = {Recent observations have revealed remarkable insights into the gas reservoir in the circumgalactic medium (CGM) of galaxy haloes. In this paper, we characterise the gas in the vicinity of Milky Way and Andromeda analogues in the hestia (High resolution Environmental Simulations of The Immediate Area) suite of constrained Local Group (LG) simulations. The hestia suite comprise of a set of three high-resolution arepo-based simulations of the LG, run using the Auriga galaxy formation model. For this paper, we focus only on the z = 0 simulation datasets and generate mock skymaps along with a power spectrum analysis to show that the distributions of ions tracing low-temperature gas (H i and Si iii) are more clumpy in comparison to warmer gas tracers (O vi, O vii and O viii). We compare to the spectroscopic CGM observations of M31 and low-redshift galaxies. hestia under-produces the column densities of the M31 observations, but the simulations are consistent with the observations of low-redshift galaxies. A possible explanation for these findings is that the spectroscopic observations of M31 are contaminated by gas residing in the CGM of the Milky Way.},
  language  = {en}
}
@article{McHuronAdamczakArnouldetal.2022,
  author    = {McHuron, Elizabeth A. and Adamczak, Stephanie and Arnould, John P. Y. and Ashe, Erin and Booth, Cormac and Bowen, W. Don and Christiansen, Fredrik and Chudzinska, Magda and Costa, Daniel P. and Fahlman, Andreas and Farmer, Nicholas A. and Fortune, Sarah M. E. and Gallagher, Cara A. and Keen, Kelly A. and Madsen, Peter T. and McMahon, Clive R. and Nabe-Nielsen, Jacob and Noren, Dawn P. and Noren, Shawn R. and Pirotta, Enrico and Rosen, David A. S. and Speakman, Cassie N. and Villegas-Amtmann, Stella and Williams, Rob},
  title     = {Key questions in marine mammal bioenergetics},
  series = {Conservation physiology},
  volume    = {10},
  journal   = {Conservation physiology},
  number    = {1},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {2051-1434},
  doi       = {10.1093/conphys/coac055},
  pages     = {17},
  year      = {2022},
  abstract  = {Bioenergetic approaches are increasingly used to understand how marine mammal populations could be affected by a changing and disturbed aquatic environment. There remain considerable gaps in our knowledge of marine mammal bioenergetics, which hinder the application of bioenergetic studies to inform policy decisions. We conducted a priority-setting exercise to identify high-priority unanswered questions in marine mammal bioenergetics, with an emphasis on questions relevant to conservation and management. Electronic communication and a virtual workshop were used to solicit and collate potential research questions from the marine mammal bioenergetic community. From a final list of 39 questions, 11 were identified as 'key'questions because they received votes from at least 50\% of survey participants. Key questions included those related to energy intake (prey landscapes, exposure to human activities) and expenditure (field metabolic rate, exposure to human activities, lactation, time-activity budgets), energy allocation priorities, metrics of body condition and relationships with survival and reproductive success and extrapolation of data from one species to another. Existing tools to address key questions include labelled water, animal-borne sensors, mark-resight data from long-term research programs, environmental DNA and unmanned vehicles. Further validation of existing approaches and development of new methodologies are needed to comprehensively address some key questions, particularly for cetaceans. The identification of these key questions can provide a guiding framework to set research priorities, which ultimately may yield more accurate information to inform policies and better conserve marine mammal populations.},
  language  = {en}
}
@article{SporbertJakubkaBucheretal.2022,
  author    = {Sporbert, Maria and Jakubka, Desiree and Bucher, Solveig Franziska and Hensen, Isabell and Freiberg, Martin and Heubach, Katja and K{\"o}nig, Andreas and Nordt, Birgit and Plos, Carolin and Blinova, Ilona and Bonn, Aletta and Knickmann, Barbara and Koubek, Tom{\´a}š and Linst{\"a}dter, Anja and Maškov{\´a}, Tereza and Primack, Richard B. and Rosche, Christoph and Shah, Manzoor A. and Stevens, Albert-Dieter and Tielb{\"o}rger, Katja and Tr{\"a}ger, Sabrina and Wirth, Christian and R{\"o}mermann, Christine},
  title     = {Functional traits influence patterns in vegetative and reproductive plant phenology - a multi-botanical garden study},
  series = {New phytologist},
  volume    = {235},
  journal   = {New phytologist},
  number    = {6},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {0028-646X},
  doi       = {10.1111/nph.18345},
  pages     = {2199 -- 2210},
  year      = {2022},
  abstract  = {Phenology has emerged as key indicator of the biological impacts of climate change, yet the role of functional traits constraining variation in herbaceous species' phenology has received little attention. Botanical gardens are ideal places in which to investigate large numbers of species growing under common climate conditions. We ask whether interspecific variation in plant phenology is influenced by differences in functional traits. We recorded onset, end, duration and intensity of initial growth, leafing out, leaf senescence, flowering and fruiting for 212 species across five botanical gardens in Germany. We measured functional traits, including plant height, absolute and specific leaf area, leaf dry matter content, leaf carbon and nitrogen content and seed mass and accounted for species' relatedness. Closely related species showed greater similarities in timing of phenological events than expected by chance, but species' traits had a high degree of explanatory power, pointing to paramount importance of species' life-history strategies. Taller plants showed later timing of initial growth, and flowered, fruited and underwent leaf senescence later. Large-leaved species had shorter flowering and fruiting durations. Taller, large-leaved species differ in their phenology and are more competitive than smaller, small-leaved species. We assume climate warming will change plant communities' competitive hierarchies with consequences for biodiversity.},
  language  = {en}
}
@article{HempelSavenjieStolterfohtetal.2022,
  author    = {Hempel, Hannes and Savenjie, Tom J. and Stolterfoht, Martin and Neu, Jens and Failla, Michele and Paingad, Vaisakh C. and Kužel, Petr and Heilweil, Edwin J. and Spies, Jacob A. and Schleuning, Markus and Zhao, Jiashang and Friedrich, Dennis and Schwarzburg, Klaus and Siebbeles, Laurens D. A. and D{\"o}rflinger, Patrick and Dyakonov, Vladimir and Katoh, Ryuzi and Hong, Min Ji and Labram, John G. and Monti, Maurizio and Butler-Caddle, Edward and Lloyd-Hughes, James and Taheri, Mohammad M. and Baxter, Jason B. and Magnanelli, Timothy J. and Luo, Simon and Cardon, Joseph M. and Ardo, Shane and Unold, Thomas},
  title     = {Predicting solar cell performance from terahertz and microwave spectroscopy},
  series = {Advanced energy materials},
  volume    = {12},
  journal   = {Advanced energy materials},
  number    = {13},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1614-6832},
  doi       = {10.1002/aenm.202102776},
  pages     = {16},
  year      = {2022},
  abstract  = {Mobilities and lifetimes of photogenerated charge carriers are core properties of photovoltaic materials and can both be characterized by contactless terahertz or microwave measurements. Here, the expertise from fifteen laboratories is combined to quantitatively model the current-voltage characteristics of a solar cell from such measurements. To this end, the impact of measurement conditions, alternate interpretations, and experimental inter-laboratory variations are discussed using a (Cs,FA,MA)Pb(I,Br)(3) halide perovskite thin-film as a case study. At 1 sun equivalent excitation, neither transport nor recombination is significantly affected by exciton formation or trapping. Terahertz, microwave, and photoluminescence transients for the neat material yield consistent effective lifetimes implying a resistance-free JV-curve with a potential power conversion efficiency of 24.6 \%. For grainsizes above approximate to 20 nm, intra-grain charge transport is characterized by terahertz sum mobilities of approximate to 32 cm(2) V-1 s(-1). Drift-diffusion simulations indicate that these intra-grain mobilities can slightly reduce the fill factor of perovskite solar cells to 0.82, in accordance with the best-realized devices in the literature. Beyond perovskites, this work can guide a highly predictive characterization of any emerging semiconductor for photovoltaic or photoelectrochemical energy conversion. A best practice for the interpretation of terahertz and microwave measurements on photovoltaic materials is presented.},
  language  = {en}
}
@article{PłociennikZawiskaRzodkiewiczetal.2022,
  author    = {Pł{\´o}ciennik, Mateusz and Zawiska, Izabela and Rzodkiewicz, Monika and Noryśkiewicz, Agnieszka M. and Słowiński, Michał and M{\"u}ller, Daniela and Brauer, Achim and Antczak-Orlewska, Olga and Kramkowski, Mateusz and Peyron, Odile and Nevalainen, Liisa and Luoto, Tomi P. and Kotrys, Bartosz and Sepp{\"a}, Heikki and Bidaurreta, Jon Camuera and Rudna, Marta and Mielczarek, Małgorzata and Zawisza, Edyta and Janowska, Ewa and Błaszkiewicz, Mirosław},
  title     = {Climatic and hydrological variability as a driver of the Lake Gościąż biota during the Younger Dryas},
  series = {Catena},
  volume    = {212},
  journal   = {Catena},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0341-8162},
  doi       = {10.1016/j.catena.2022.106049},
  pages     = {15},
  year      = {2022},
  abstract  = {The Younger Dryas (YD) is a roughly 1,100-year cold period marking the end of the last glaciation. Climate modelling for northern Europe indicates high summer temperatures and strong continentality. In eastern Europe, the scale of temperature variation and its influence on ecosystems is weakly recognised. Here, we present a multi-proxy reconstruction of YD conditions from Lake Gos ' ciaz (central Poland). The decadal-resolution analysis of its annually varved sediments indicates an initial decrease in Chironomidae-inferred mean July air temperature followed by steady warming. The pollen-inferred winter-to-summer temperature amplitude and annual precip-itation is highest at the Allerod/YD transition and the early YD (ca. 12.7-12.4 ky cal BP) and YD/Holocene (11.7-11.4 ka cal BP) transition. Temperature and precipitation were the main reasons for lake level fluctuations as reflected in the planktonic/littoral Cladocera ratio. The lake's diatom-inferred total phosphorus decreased with increasing summer temperature from about mid YD. Windy conditions in the early YD until ~12.3 ka cal BP caused water mixing and a short-lived/temporary increase in nutrient availability for phytoplankton. The Chironomidae-inferred summer temperature and pollen inferred summer temperature, winter temperature and annual precipitation herein are one of only a few in eastern Europe conducted with such high resolution.},
  language  = {en}
}
@article{HuthPangTewsetal.2022,
  author    = {Huth, Sabrina and Pang, Peter Tsun Ho and Tews, Ingo and Dietrich, Tim and Le F{\`e}vre, Arnaud and Schwenk, Achim and Trautmann, Wolfgang and Agarwal, Kshitij and Bulla, Mattia and Coughlin, Michael W. and Van den Broeck, Chris},
  title     = {Constraining neutron-star matter with microscopic and macroscopic collisions},
  series = {Nature : the international weekly journal of science},
  volume    = {606},
  journal   = {Nature : the international weekly journal of science},
  number    = {7913},
  publisher = {Nature Publ. Group},
  address   = {London [u.a.]},
  issn      = {0028-0836},
  doi       = {10.1038/s41586-022-04750-w},
  pages     = {276 -- 295},
  year      = {2022},
  abstract  = {Interpreting high-energy, astrophysical phenomena, such as supernova explosions or neutron-star collisions, requires a robust understanding of matter at supranuclear densities. However, our knowledge about dense matter explored in the cores of neutron stars remains limited. Fortunately, dense matter is not probed only in astrophysical observations, but also in terrestrial heavy-ion collision experiments. Here we use Bayesian inference to combine data from astrophysical multi-messenger observations of neutron stars(1-9) and from heavy-ion collisions of gold nuclei at relativistic energies(10,11) with microscopic nuclear theory calculations(12-17) to improve our understanding of dense matter. We find that the inclusion of heavy-ion collision data indicates an increase in the pressure in dense matter relative to previous analyses, shifting neutron-star radii towards larger values, consistent with recent observations by the Neutron Star Interior Composition Explorer mission(5-8,18). Our findings show that constraints from heavy-ion collision experiments show a remarkable consistency with multi-messenger observations and provide complementary information on nuclear matter at intermediate densities. This work combines nuclear theory, nuclear experiment and astrophysical observations, and shows how joint analyses can shed light on the properties of neutron-rich supranuclear matter over the density range probed in neutron stars.},
  language  = {en}
}
@article{VencesKoehlerCrottinietal.2022,
  author    = {Vences, Miguel and K{\"o}hler, J{\"o}rn and Crottini, Angelica and Hofreiter, Michael and Hutter, Carl R. and du Preez, Louis and Preick, Michaela and Rakotoarison, Andolalao and Rancilhac, Lo{\"i}s and Raselimanana, Achille P. and Rosa, Gon{\c{c}}alo M. and Scherz, Mark D. and Glaw, Frank},
  title     = {An integrative taxonomic revision and redefinition of Gephyromantis (Laurentomantis) malagasius based on archival DNA analysis reveals four new mantellid frog species from Madagascar},
  series = {Vertebrate zoology},
  volume    = {72},
  journal   = {Vertebrate zoology},
  publisher = {Senckenberg Gesellschaft f{\"u}r Naturforschung},
  address   = {Frankfurt am Main},
  issn      = {1864-5755},
  doi       = {10.3897/vz.72.e78830},
  pages     = {271 -- 309},
  year      = {2022},
  abstract  = {The subgenus Laurentomantis in the genus Gephyromantis contains some of the least known amphibian species of Madagascar. The six currently valid nominal species are rainforest frogs known from few individuals, hampering a full understanding of the species diversity of the clade. We assembled data on specimens collected during field surveys over the past 30 years and integrated analysis of mitochondrial and nuclear-encoded genes of 88 individuals, a comprehensive bioacoustic analysis, and morphological comparisons to delimit a minimum of nine species-level lineages in the subgenus. To clarify the identity of the species Gephyromantis malagasius, we applied a target-enrichment approach to a sample of the 110 year old holotype of Microphryne malagasia Methuen and Hewitt, 1913 to assign this specimen to a lineage based on a mitochondrial DNA barcode. The holotype clustered unambiguously with specimens previously named G. ventrimaculatus. Consequently we propose to consider Trachymantis malagasia ventrimaculatus Angel, 1935 as a junior synonym of Gephyromantis malagasius. Due to this redefinition of G. malagasius, no scientific name is available for any of the four deep lineages of frogs previously subsumed under this name, all characterized by red color ventrally on the hindlimbs. These are here formally named as Gephyromantis fiharimpe sp. nov., G. matsilo sp. nov., G. oelkrugi sp. nov., and G. portonae sp. nov. The new species are distinguishable from each other by genetic divergences of >4\% uncorrected pairwise distance in a fragment of the 16S rRNA marker and a combination of morphological and bioacoustic characters. Gephyromantis fiharimpe and G. matsilo occur, respectively, at mid-elevations and lower elevations along a wide stretch of Madagascar's eastern rainforest band, while G. oelkrugi and G. portonae appear to be more range-restricted in parts of Madagascar's North East and Northern Central East regions. Open taxonomic questions surround G. horridus, to which we here assign specimens from Montagne d'Ambre and the type locality Nosy Be; and G. ranjomavo, which contains genetically divergent populations from Marojejy, Tsaratanana, and Ampotsidy.},
  language  = {en}
}
@article{VogelClausAhringetal.2022,
  author    = {Vogel, Annemarie and Claus, Inga and Ahring, Sigrid and Gruber, Doreen and Haghikia, Aiden and Frank, Ulrike and Dziewas, Rainer and Ebersbach, Georg and Gandor, Florin and Warnecke, Tobias},
  title     = {Endoscopic characteristics of dysphagia in multiple system atrophy},
  series = {Movement disorders : official journal of the Movement Disorder Society},
  volume    = {37},
  journal   = {Movement disorders : official journal of the Movement Disorder Society},
  number    = {3},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken},
  issn      = {0885-3185},
  doi       = {10.1002/mds.28854},
  pages     = {535 -- 544},
  year      = {2022},
  abstract  = {Background Dysphagia is a major clinical concern in multiple system atrophy (MSA). A detailed evaluation of its major endoscopic features compared with Parkinson's disease (PD) is lacking. Objective This study systematically assessed dysphagia in MSA compared with PD and correlated subjective dysphagia to objective endoscopic findings. Methods Fifty-seven patients with MSA (median, 64 [interquartile range (IQR): 59-71] years; 35 women) underwent flexible endoscopic evaluation of swallowing using a specific MSA-flexible endoscopic evaluation of swallowing task protocol. Findings were compared with an age-matched cohort of 57 patients with PD (median, 67 [interquartile range: 60-73] years; 28 women). In a subcohort, subjective dysphagia was assessed using the Swallowing Disturbance Questionnaire and correlated to endoscopy findings. Results Patients with MSA predominantly showed symptoms suggestive of oral-phase disturbance (premature spillage, 75.4\%, piecemeal deglutition, 75.4\%). Pharyngeal-phase symptoms occurred less often (pharyngeal residues, 50.9\%; penetration/aspiration, 28.1\%). In contrast, pharyngeal symptoms were the most common finding in PD (pharyngeal residues, 47.4\%). Oral symptoms occurred less frequently in PD (premature spillage, 15.8\%, P < 0.001; piecemeal deglutition, 1.8\%, P < 0.01). Patients with MSA had a greater risk for oral-phase disturbances with increased disease severity (P < 0.05; odds ratio, 3.15). Patients with MSA showed a significantly higher intraindividual interswallow variability compared with PD. When correlating Swallowing Disturbance Questionnaire scores with endoscopy results, its cutoff, validated for PD, was not sensitive enough to identify patients with MSA with dysphagia. We developed a subscore for identifying dysphagia in MSA and calculated a new cutoff (sensitivity 85\%, specificity 100\%). Conclusions In contrast with patients with PD, patients with dysphagic MSA more frequently present with oral-phase symptoms and a significantly higher intraindividual interswallow variability. A novel Swallowing Disturbance Questionnaire MSA subscore may be a valuable tool to identify patients with MSA with early oropharyngeal dysphagia.},
  language  = {en}
}
@article{LupienRussellPearsonetal.2022,
  author    = {Lupien, Rachel L. and Russell, James M. and Pearson, Emma J. and Castaneda, Isla S. and Asrat, Asfawossen and F{\"o}rster, Verena and Lamb, Henry F. and Roberts, Helen M. and Sch{\"a}bitz, Frank and Trauth, Martin H. and Beck, Catherine C. and Feibel, Craig S. and Cohen, Andrew S.},
  title     = {Orbital controls on eastern African hydroclimate in the Pleistocene},
  series = {Scientific reports},
  volume    = {12},
  journal   = {Scientific reports},
  number    = {1},
  publisher = {Macmillan Publishers Limited},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-022-06826-z},
  pages     = {10},
  year      = {2022},
  abstract  = {Understanding eastern African paleoclimate is critical for contextualizing early human evolution, adaptation, and dispersal, yet Pleistocene climate of this region and its governing mechanisms remain poorly understood due to the lack of long, orbitally-resolved, terrestrial paleoclimate records. Here we present leaf wax hydrogen isotope records of rainfall from paleolake sediment cores from key time windows that resolve long-term trends, variations, and high-latitude effects on tropical African precipitation. Eastern African rainfall was dominantly controlled by variations in low-latitude summer insolation during most of the early and middle Pleistocene, with little evidence that glacial-interglacial cycles impacted rainfall until the late Pleistocene. We observe the influence of high-latitude-driven climate processes emerging from the last interglacial (Marine Isotope Stage 5) to the present, an interval when glacial-interglacial cycles were strong and insolation forcing was weak. Our results demonstrate a variable response of eastern African rainfall to low-latitude insolation forcing and high-latitude-driven climate change, likely related to the relative strengths of these forcings through time and a threshold in monsoon sensitivity. We observe little difference in mean rainfall between the early, middle, and late Pleistocene, which suggests that orbitally-driven climate variations likely played a more significant role than gradual change in the relationship between early humans and their environment.},
  language  = {en}
}
@article{EssenSternHaaseetal.2022,
  author    = {Essen, Anna and Stern, Ariel Dora and Haase, Christoffer Bjerre and Car, Josip and Greaves, Felix and Paparova, Dragana and Vandeput, Steven and Wehrens, Rik and Bates, David W.},
  title     = {Health app policy},
  series = {npj digital medicine},
  volume    = {5},
  journal   = {npj digital medicine},
  number    = {1},
  publisher = {Macmillan Publishers Limited},
  address   = {Basingstoke},
  issn      = {2398-6352},
  doi       = {10.1038/s41746-022-00573-1},
  pages     = {10},
  year      = {2022},
  abstract  = {An abundant and growing supply of digital health applications (apps) exists in the commercial tech-sector, which can be bewildering for clinicians, patients, and payers. A growing challenge for the health care system is therefore to facilitate the identification of safe and effective apps for health care practitioners and patients to generate the most health benefit as well as guide payer coverage decisions. Nearly all developed countries are attempting to define policy frameworks to improve decision-making, patient care, and health outcomes in this context. This study compares the national policy approaches currently in development/use for health apps in nine countries. We used secondary data, combined with a detailed review of policy and regulatory documents, and interviews with key individuals and experts in the field of digital health policy to collect data about implemented and planned policies and initiatives. We found that most approaches aim for centralized pipelines for health app approvals, although some countries are adding decentralized elements. While the countries studied are taking diverse paths, there is nevertheless broad, international convergence in terms of requirements in the areas of transparency, health content, interoperability, and privacy and security. The sheer number of apps on the market in most countries represents a challenge for clinicians and patients. Our analyses of the relevant policies identified challenges in areas such as reimbursement, safety, and privacy and suggest that more regulatory work is needed in the areas of operationalization, implementation and international transferability of approvals. Cross-national efforts are needed around regulation and for countries to realize the benefits of these technologies.},
  language  = {en}
}
@article{EsmaeilishirazifardUsherTrimetal.2022,
  author    = {Esmaeilishirazifard, Elham and Usher, Louise and Trim, Carol and Denise, Hubert and Sangal, Vartul and Tyson, Gregory H. and Barlow, Axel and Redway, Keith F. and Taylor, John D. and Kremyda-Vlachou, Myrto and Davies, Sam and Loftus, Teresa D. and Lock, Mikaella M. G. and Wright, Kstir and Dalby, Andrew and Snyder, Lori A. S. and Wuster, Wolfgang and Trim, Steve and Moschos, Sterghios A.},
  title     = {Bacterial adaptation to venom in snakes and arachnida},
  series = {Microbiology spectrum},
  volume    = {10},
  journal   = {Microbiology spectrum},
  number    = {3},
  publisher = {American Society for Microbiology},
  address   = {Birmingham, Ala.},
  issn      = {2165-0497},
  doi       = {10.1128/spectrum.02408-21},
  pages     = {16},
  year      = {2022},
  abstract  = {Notwithstanding their 3 to 5\% mortality, the 2.7 million envenomation-related injuries occurring annually-predominantly across Africa, Asia, and Latin America-are also major causes of morbidity. Venom toxin-damaged tissue will develop infections in some 75\% of envenomation victims, with E. faecalis being a common culprit of disease; however, such infections are generally considered to be independent of envenomation. Animal venoms are considered sterile sources of antimicrobial compounds with strong membrane-disrupting activity against multidrug-resistant bacteria. However, venomous bite wound infections are common in developing nations. Investigating the envenomation organ and venom microbiota of five snake and two spider species, we observed venom community structures that depend on the host venomous animal species and evidenced recovery of viable microorganisms from black-necked spitting cobra (Naja nigricollis) and Indian ornamental tarantula (Poecilotheria regalis) venoms. Among the bacterial isolates recovered from N. nigricollis, we identified two venom-resistant, novel sequence types of Enterococcus faecalis whose genomes feature 16 virulence genes, indicating infectious potential, and 45 additional genes, nearly half of which improve bacterial membrane integrity. Our findings challenge the dogma of venom sterility and indicate an increased primary infection risk in the clinical management of venomous animal bite wounds. IMPORTANCE Notwithstanding their 3 to 5\% mortality, the 2.7 million envenomation-related injuries occurring annually-predominantly across Africa, Asia, and Latin America-are also major causes of morbidity. Venom toxin-damaged tissue will develop infections in some 75\% of envenomation victims, with E. faecalis being a common culprit of disease; however, such infections are generally considered to be independent of envenomation. Here, we provide evidence on venom microbiota across snakes and arachnida and report on the convergent evolution mechanisms that can facilitate adaptation to black-necked cobra venom in two independent E. faecalis strains, easily misidentified by biochemical diagnostics. Therefore, since inoculation with viable and virulence gene-harboring bacteria can occur during envenomation, acute infection risk management following envenomation is warranted, particularly for immunocompromised and malnourished victims in resource-limited settings. These results shed light on how bacteria evolve for survival in one of the most extreme environments on Earth and how venomous bites must be also treated for infections.},
  language  = {en}
}
@article{RiemannRahavPassowetal.2022,
  author    = {Riemann, Lasse and Rahav, Eyal and Passow, Uta and Grossart, Hans-Peter and de Beer, Dirk and Klawonn, Isabell and Eichner, Meri and Benavides, Mar and Bar-Zeev, Edo},
  title     = {Planktonic aggregates as hotspots for heterotrophic diazotrophy: the plot thickens},
  series = {Frontiers in microbiology},
  volume    = {13},
  journal   = {Frontiers in microbiology},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-302X},
  doi       = {10.3389/fmicb.2022.875050},
  pages     = {9},
  year      = {2022},
  abstract  = {Biological dinitrogen (N-2) fixation is performed solely by specialized bacteria and archaea termed diazotrophs, introducing new reactive nitrogen into aquatic environments. Conventionally, phototrophic cyanobacteria are considered the major diazotrophs in aquatic environments. However, accumulating evidence indicates that diverse non-cyanobacterial diazotrophs (NCDs) inhabit a wide range of aquatic ecosystems, including temperate and polar latitudes, coastal environments and the deep ocean. NCDs are thus suspected to impact global nitrogen cycling decisively, yet their ecological and quantitative importance remain unknown. Here we review recent molecular and biogeochemical evidence demonstrating that pelagic NCDs inhabit and thrive especially on aggregates in diverse aquatic ecosystems. Aggregates are characterized by reduced-oxygen microzones, high C:N ratio (above Redfield) and high availability of labile carbon as compared to the ambient water. We argue that planktonic aggregates are important loci for energetically-expensive N-2 fixation by NCDs and propose a conceptual framework for aggregate-associated N-2 fixation. Future studies on aggregate-associated diazotrophy, using novel methodological approaches, are encouraged to address the ecological relevance of NCDs for nitrogen cycling in aquatic environments.},
  language  = {en}
}
@article{SchulteMeucciStoofLeichsenringetal.2022,
  author    = {Schulte, Luise and Meucci, Stefano and Stoof-Leichsenring, Kathleen R. and Heitkam, Tony and Schmidt, Nicola and von Hippel, Barbara and Andreev, Andrei A. and Diekmann, Bernhard and Biskaborn, Boris and Wagner, Bernd and Melles, Martin and Pestryakova, Lyudmila A. and Alsos, Inger G. and Clarke, Charlotte and Krutovsky, Konstantin and Herzschuh, Ulrike},
  title     = {Larix species range dynamics in Siberia since the Last Glacial captured from sedimentary ancient DNA},
  series = {Communications biology},
  volume    = {5},
  journal   = {Communications biology},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2399-3642},
  doi       = {10.1038/s42003-022-03455-0},
  pages     = {11},
  year      = {2022},
  abstract  = {Climate change is expected to cause major shifts in boreal forests which are in vast areas of Siberia dominated by two species of the deciduous needle tree larch (Larix). The species differ markedly in their ecosystem functions, thus shifts in their respective ranges are of global relevance. However, drivers of species distribution are not well understood, in part because paleoecological data at species level are lacking. This study tracks Larix species distribution in time and space using target enrichment on sedimentary ancient DNA extracts from eight lakes across Siberia. We discovered that Larix sibirica, presently dominating in western Siberia, likely migrated to its northern distribution area only in the Holocene at around 10,000 years before present (ka BP), and had a much wider eastern distribution around 33 ka BP. Samples dated to the Last Glacial Maximum (around 21 ka BP), consistently show genotypes of L. gmelinii. Our results suggest climate as a strong determinant of species distribution in Larix and provide temporal and spatial data for species projection in a changing climate. Using ancient sedimentary DNA from up to 50 kya, dramatic distributional shifts are documented in two dominant boreal larch species, likely guided by environmental changes suggesting climate as a strong determinant of species distribution.},
  language  = {en}
}
@article{PetrovSingerCoughlinetal.2022,
  author    = {Petrov, Polina and Singer, Leo P. and Coughlin, Michael W. and Kumar, Vishwesh and Almualla, Mouza and Anand, Shreya and Bulla, Mattia and Dietrich, Tim and Foucart, Francois and Guessoum, Nidhal},
  title     = {Data-driven expectations for electromagnetic counterpart searches based on LIGO/Virgo public alerts},
  series = {The astrophysical journal : an international review of spectroscopy and astronomical physics; part 1},
  volume    = {924},
  journal   = {The astrophysical journal : an international review of spectroscopy and astronomical physics; part 1},
  number    = {2},
  publisher = {Institute of Physics Publ.},
  address   = {London},
  issn      = {1538-4357},
  doi       = {10.3847/1538-4357/ac366d},
  pages     = {10},
  year      = {2022},
  abstract  = {Searches for electromagnetic counterparts of gravitational-wave signals have redoubled since the first detection in 2017 of a binary neutron star merger with a gamma-ray burst, optical/infrared kilonova, and panchromatic afterglow. Yet, one LIGO/Virgo observing run later, there has not yet been a second, secure identification of an electromagnetic counterpart. This is not surprising given that the localization uncertainties of events in LIGO and Virgo's third observing run, O3, were much larger than predicted. We explain this by showing that improvements in data analysis that now allow LIGO/Virgo to detect weaker and hence more poorly localized events have increased the overall number of detections, of which well-localized, gold-plated events make up a smaller proportion overall. We present simulations of the next two LIGO/Virgo/KAGRA observing runs, O4 and O5, that are grounded in the statistics of O3 public alerts. To illustrate the significant impact that the updated predictions can have, we study the follow-up strategy for the Zwicky Transient Facility. Realistic and timely forecasting of gravitational-wave localization accuracy is paramount given the large commitments of telescope time and the need to prioritize which events are followed up. We include a data release of our simulated localizations as a public proposal planning resource for astronomers.},
  language  = {en}
}
@article{DunkerBoydDurkaetal.2022,
  author    = {Dunker, Susanne and Boyd, Matthew and Durka, Walter and Erler, Silvio and Harpole, W. Stanley and Henning, Silvia and Herzschuh, Ulrike and Hornick, Thomas and Knight, Tiffany and Lips, Stefan and M{\"a}der, Patrick and Švara, Elena Motivans and Mozarowski, Steven and Rakosy, Demetra and R{\"o}mermann, Christine and Schmitt-Jansen, Mechthild and Stoof-Leichsenring, Kathleen and Stratmann, Frank and Treudler, Regina and Virtanen, Risto and Wendt-Potthoff, Katrin and Wilhelm, Christian},
  title     = {The potential of multispectral imaging flow cytometry for environmental monitoring},
  series = {Cytometry part A},
  volume    = {101},
  journal   = {Cytometry part A},
  number    = {9},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1552-4922},
  doi       = {10.1002/cyto.a.24658},
  pages     = {782 -- 799},
  year      = {2022},
  abstract  = {Environmental monitoring involves the quantification of microscopic cells and particles such as algae, plant cells, pollen, or fungal spores. Traditional methods using conventional microscopy require expert knowledge, are time-intensive and not well-suited for automated high throughput. Multispectral imaging flow cytometry (MIFC) allows measurement of up to 5000 particles per second from a fluid suspension and can simultaneously capture up to 12 images of every single particle for brightfield and different spectral ranges, with up to 60x magnification. The high throughput of MIFC has high potential for increasing the amount and accuracy of environmental monitoring, such as for plant-pollinator interactions, fossil samples, air, water or food quality that currently rely on manual microscopic methods. Automated recognition of particles and cells is also possible, when MIFC is combined with deep-learning computational techniques. Furthermore, various fluorescence dyes can be used to stain specific parts of the cell to highlight physiological and chemical features including: vitality of pollen or algae, allergen content of individual pollen, surface chemical composition (carbohydrate coating) of cells, DNA- or enzyme-activity staining. Here, we outline the great potential for MIFC in environmental research for a variety of research fields and focal organisms. In addition, we provide best practice recommendations.},
  language  = {en}
}
@article{DeFelipeAlcaldeBaykievetal.2022,
  author    = {DeFelipe, Irene and Alcalde, Juan and Baykiev, Eldar and Bernal, Isabel and Boonma, Kittiphon and Carbonell, Ramon and Flude, Stephanie and Folch, Arnau and Fullea, Javier and Garc{\´i}a-Castellanos, Daniel and Geyer, Adelina and Giralt, Santiago and Hern{\´a}ndez, Armand and Jim{\´e}nez-Munt, Ivone and Kumar, Ajay and Llorens, Maria-Gema and Mart{\´i}, Joan and Molina, Cecilia and Olivar-Casta{\~n}o, Andr{\´e}s and Parnell, Andrew and Schimmel, Martin and Torn{\´e}, Montserrat and Ventosa, Sergi},
  title     = {Towards a digital twin of the Earth system: Geo-Soft-CoRe, a geoscientific software \& code repository},
  series = {Frontiers in earth science},
  volume    = {10},
  journal   = {Frontiers in earth science},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-6463},
  doi       = {10.3389/feart.2022.828005},
  pages     = {20},
  year      = {2022},
  abstract  = {The immense advances in computer power achieved in the last decades have had a significant impact in Earth science, providing valuable research outputs that allow the simulation of complex natural processes and systems, and generating improved forecasts. The development and implementation of innovative geoscientific software is currently evolving towards a sustainable and efficient development by integrating models of different aspects of the Earth system. This will set the foundation for a future digital twin of the Earth. The codification and update of this software require great effort from research groups and therefore, it needs to be preserved for its reuse by future generations of geoscientists. Here, we report on Geo-Soft-CoRe, a Geoscientific Software \& Code Repository, hosted at the archive DIGITAL.CSIC. This is an open source, multidisciplinary and multiscale collection of software and code developed to analyze different aspects of the Earth system, encompassing tools to: 1) analyze climate variability; 2) assess hazards, and 3) characterize the structure and dynamics of the solid Earth. Due to the broad range of applications of these software packages, this collection is useful not only for basic research in Earth science, but also for applied research and educational purposes, reducing the gap between the geosciences and the society. By providing each software and code with a permanent identifier (DOI), we ensure its self-sustainability and accomplish the FAIR (Findable, Accessible, Interoperable and Reusable) principles. Therefore, we aim for a more transparent science, transferring knowledge in an easier way to the geoscience community, and encouraging an integrated use of computational infrastructure.},
  language  = {en}
}
@article{GrohDiamantopoulosDuanetal.2022,
  author    = {Groh, Jannis and Diamantopoulos, Efstathios and Duan, Xiaohong and Ewert, Frank and Heinlein, Florian and Herbst, Michael and Holbak, Maja and Kamali, Bahareh and Kersebaum, Kurt-Christian and Kuhnert, Matthias and Nendel, Claas and Priesack, Eckart and Steidl, J{\"o}rg and Sommer, Michael and P{\"u}tz, Thomas and Vanderborght, Jan and Vereecken, Harry and Wallor, Evelyn and Weber, Tobias K. D. and Wegehenkel, Martin and Weiherm{\"u}ller, Lutz and Gerke, Horst H.},
  title     = {Same soil, different climate: Crop model intercomparison on translocated lysimeters},
  series = {Vadose zone journal},
  volume    = {21},
  journal   = {Vadose zone journal},
  number    = {4},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1539-1663},
  doi       = {10.1002/vzj2.20202},
  pages     = {25},
  year      = {2022},
  abstract  = {Crop model intercomparison studies have mostly focused on the assessment of predictive capabilities for crop development using weather and basic soil data from the same location. Still challenging is the model performance when considering complex interrelations between soil and crop dynamics under a changing climate. The objective of this study was to test the agronomic crop and environmental flux-related performance of a set of crop models. The aim was to predict weighing lysimeter-based crop (i.e., agronomic) and water-related flux or state data (i.e., environmental) obtained for the same soil monoliths that were taken from their original environment and translocated to regions with different climatic conditions, after model calibration at the original site. Eleven models were deployed in the study. The lysimeter data (2014-2018) were from the Dedelow (Dd), Bad Lauchstadt (BL), and Selhausen (Se) sites of the TERENO (TERrestrial ENvironmental Observatories) SOILCan network. Soil monoliths from Dd were transferred to the drier and warmer BL site and the wetter and warmer Se site, which allowed a comparison of similar soil and crop under varying climatic conditions. The model parameters were calibrated using an identical set of crop- and soil-related data from Dd. Environmental fluxes and crop growth of Dd soil were predicted for conditions at BL and Se sites using the calibrated models. The comparison of predicted and measured data of Dd lysimeters at BL and Se revealed differences among models. At site BL, the crop models predicted agronomic and environmental components similarly well. Model performance values indicate that the environmental components at site Se were better predicted than agronomic ones. The multi-model mean was for most observations the better predictor compared with those of individual models. For Se site conditions, crop models failed to predict site-specific crop development indicating that climatic conditions (i.e., heat stress) were outside the range of variation in the data sets considered for model calibration. For improving predictive ability of crop models (i.e., productivity and fluxes), more attention should be paid to soil-related data (i.e., water fluxes and system states) when simulating soil-crop-climate interrelations in changing climatic conditions.},
  language  = {en}
}
@article{CaoChenTianetal.2022,
  author    = {Cao, Xianyong and Chen, Jianhui and Tian, Fang and Xu, Qinghai and Herzschuh, Ulrike and Telford, Richard and Huang, Xiaozhong and Zheng, Zhuo and Shen, Caiming and Li, Wenjia},
  title     = {Long-distance modern analogues bias results of pollen-based precipitation reconstructions},
  series = {Science bulletin},
  volume    = {67},
  journal   = {Science bulletin},
  number    = {11},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2095-9273},
  doi       = {10.1016/j.scib.2022.01.003},
  pages     = {1115 -- 1117},
  year      = {2022},
  language  = {en}
}
@article{WittenbecherCuadratJohnstonetal.2022,
  author    = {Wittenbecher, Clemens and Cuadrat, Rafael and Johnston, Luke and Eichelmann, Fabian and J{\"a}ger, Susanne and Kuxhaus, Olga and Prada, Marcela and Del Greco, Fabiola M. and Hicks, Andrew A. and Hoffman, Per and Krumsiek, Jan and Hu, Frank B. and Schulze, Matthias B.},
  title     = {Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology},
  series = {Nature communications},
  volume    = {13},
  journal   = {Nature communications},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-022-28496-1},
  pages     = {13},
  year      = {2022},
  abstract  = {Metabolic alterations precede cardiometabolic disease onset. Here we present ceramide- and dihydroceramide-profiling data from a nested case-cohort (type 2 diabetes [T2D, n = 775]; cardiovascular disease [CVD, n = 551]; random subcohort [n = 1137]) in the prospective EPIC-Potsdam study. We apply the novel NetCoupler-algorithm to link a data-driven (dihydro)ceramide network to T2D and CVD risk. Controlling for confounding by other (dihydro)ceramides, ceramides C18:0 and C22:0 and dihydroceramides C20:0 and C22:2 are associated with higher and ceramide C20:0 and dihydroceramide C26:1 with lower T2D risk. Ceramide C16:0 and dihydroceramide C22:2 are associated with higher CVD risk. Genome-wide association studies and Mendelian randomization analyses support a role of ceramide C22:0 in T2D etiology. Our results also suggest that (dh)ceramides partly mediate the putative adverse effect of high red meat consumption and benefits of coffee consumption on T2D risk. Thus, (dihydro)ceramides may play a critical role in linking genetic predisposition and dietary habits to cardiometabolic disease risk.},
  language  = {en}
}
@article{HeinMurphy2022,
  author    = {Hein, Johannes and Murphy, Andrew},
  title     = {VP-nominalization and the Final-over-Final Condition},
  series = {Linguistic inquiry},
  volume    = {53},
  journal   = {Linguistic inquiry},
  number    = {2},
  publisher = {MIT Press},
  address   = {Cambridge, Mass.},
  issn      = {0024-3892},
  doi       = {10.1162/ling_a_00407},
  pages     = {337 -- 370},
  year      = {2022},
  abstract  = {The Final-over-Final Condition has emerged as a robust and explanatory generalization for a wide range of phenomena (Biberauer, Holmberg, and Roberts 2014, Sheehan et al. 2017). In this article, we argue that it also holds in another domain, nominalization. In languages that show overt nominalization of VPs, one word order is routinely unattested, namely, a head-initial VP with a suffixal nominalizer. This typological gap can be accounted for by the Final-over-Final Condition, if we allow it to hold within mixed extended projections. This view also makes correct predictions about agentive nominalizations and nominalized serial verb constructions.},
  language  = {en}
}
@article{KollmannRoussosClarketal.2022,
  author    = {Kollmann, Peter and Roussos, Elias and Clark, George and Cooper, John F. and Sturner, Steven J. and Kotova, Anna and Regoli, Leonardo and Shprits, Yuri Y. and Aseev, Nikita and Krupp, Norbert},
  title     = {Spectra of Saturn's proton belts revealed},
  series = {Icarus},
  volume    = {376},
  journal   = {Icarus},
  publisher = {Elsevier},
  address   = {San Diego},
  issn      = {0019-1035},
  doi       = {10.1016/j.icarus.2021.114795},
  pages     = {17},
  year      = {2022},
  abstract  = {Saturn is permanently surrounded by 6 discrete proton radiation belts that are rigidly separated by the orbits of its inner moons and dense rings. These radiation belts are ideal environments to study the details of radial diffusion and the CRAND source process, yet progress has been hindered by the fact that the energy spectra are not known with certainty: Reanalysis of the response functions of the LEMMS instrument on-board the Cassini orbiter has shown that measurements of less than or similar to 10 MeV protons may be easily contaminated by greater than or similar to 10 MeV protons and that many available measurements characterize a very broad energy range, so that the calculation of an energy-resolved spectrum is not as straightforward as previously assumed. Here we use forward modeling of the measurements based on the instrument response and combine this technique where useful with numerical modeling of the proton belt physics in order to determine Saturn's spectra with higher certainty. We find significant proton intensities up to approximate to 1 GeV. While earlier studies reported on proton spectra roughly following a power law with exponent approximate to -2, our more advanced analysis shows harder spectra with exponent approximate to -1. The observed spectra provide independent confirmation that Saturn's proton belts are sourced by CRAND and are consistent with the provided protons being subsequently cooled in the tenuous gas originating from Saturn or Enceladus. The intensities at Saturn are found to be lower than at Jupiter and Earth, which is also consistent with the source of Saturn being exclusively CRAND, while the other planets can draw from additional processes. Our new spectra can be used in the future to further our understanding of Saturn's proton belts and the respective physical processes that occur at other magnetized planets in general. Also, the spectra have applications for several topics of planetary science, such as space weathering of Saturn's moons and rings, and can be useful to constrain properties of the main rings through their production of secondary particles.},
  language  = {en}
}
@article{RosaDewaeleGarbarinoetal.2022,
  author    = {Rosa, Angelika D. and Dewaele, Agn{\`e}s and Garbarino, Gaston and Svitlyk, Volodymyr and Morard, Guillaume and De Angelis, Filippo and Krstulovic, Marija and Briggs, Richard and Irifune, Tetsuo and Mathon, Olivier and Bouhifd, Mohamed Ali},
  title     = {Martensitic fcc-hcp transformation pathway in solid krypton and xenon and its effect on their equations of state},
  series = {Physical review / publ. by The American Institute of Physics. B},
  volume    = {105},
  journal   = {Physical review / publ. by The American Institute of Physics. B},
  number    = {14},
  publisher = {American Physical Society},
  address   = {College Park},
  issn      = {2469-9950},
  doi       = {10.1103/PhysRevB.105.144103},
  pages     = {14},
  year      = {2022},
  abstract  = {The martensitic transformation is a fundamental physical phenomenon at the origin of important industrial applications. However, the underlying microscopic mechanism, which is of critical importance to explain the outstanding mechanical properties of martensitic materials, is still not fully understood. This is because for most martensitic materials the transformation is a fast process that makes in situ studies extremely challenging. Noble solids krypton and xenon undergo a progressive pressure-induced face-centered cubic (fcc) to hexagonal close-packed (hcp) martensitic transition with a very wide coexistence domain. Here, we took advantage of this unique feature to study the detailed transformation progress at the atomic level by employing in situ x-ray diffraction and absorption spectroscopy. We evidenced a four-stage pathway and suggest that the lattice mismatch between the fcc and hcp forms plays a key role in the generation of strain. We also determined precisely the effect of the transformation on the compression behavior of these materials.},
  language  = {en}
}
@article{SchaererIzotovWorsecketal.2022,
  author    = {Schaerer, Daniel and Izotov, Yuri I. and Worseck, G{\´a}bor and Berg, Danielle and Chisholm, John and Jaskot, Anne and Nakajima, Kimihiko and Ravindranath, Swara and Thuan, Trinh X. and Verhamme, Anne},
  title     = {Strong Lyman continuum emitting galaxies show intense C IV λ 1550 emission},
  series = {Astronomy and astrophysics},
  volume    = {658},
  journal   = {Astronomy and astrophysics},
  publisher = {EDP Sciences},
  address   = {Les Ulis},
  issn      = {0004-6361},
  doi       = {10.1051/0004-6361/202243149},
  pages     = {6},
  year      = {2022},
  abstract  = {Using the Space Telescope Imaging Spectrograph, we have obtained ultraviolet spectra from similar to 1200 to 2000 angstrom of known Lyman continuum (LyC) emitting galaxies at low redshift (z similar to 0.3-0.4) with varying absolute LyC escape fractions ( f(esc) similar to 0.01-0.72). Our observations include in particular the galaxy J1243+4646, which has the highest known LyC escape fraction at low redshift. While all galaxies are known Lyman alpha emitters, we consistently detect an inventory of additional emission lines, including C IV lambda 1550, He II lambda 1640, O III] lambda 1666, and C III] lambda 1909, whose origin is presumably essentially nebular. C IV lambda 1550 emission is detected above 4 sigma in six out of eight galaxies, with equivalent widths of EW(C IV) = 12-15 angstrom for two galaxies, which exceeds the previously reported maximum emission in low-z star-forming galaxies. We detect C IV lambda 1550 emission in all LyC emitters with escape fractions f(esc) > 0.1 and find a tentative increase in the flux ratio C IV lambda 1550 /C III] lambda 1909 with f(esc). Based on the data, we propose a new criterion to select and classify strong leakers (galaxies with f(esc) > 0.1): C IV lambda 1550 /C III] lambda 1909 greater than or similar to 0.75. Finally, we also find He II lambda 1640 emission in all the strong leakers with equivalent widths from 3 to 8 angstrom rest frame. These are among the highest values observed in star-forming galaxies and are primarily due to a high rate of ionizing photon production. The nebular He II lambda 1640 emission of the strong LyC emitters does not require harder ionizing spectra at >54 eV compared to those of typical star-forming galaxies at similarly low metallicity.},
  language  = {en}
}
@article{BirukovGlintborgSchulzeetal.2022,
  author    = {Birukov, Anna and Glintborg, Dorte and Schulze, Matthias B. and Jensen, Tina K. and Kuxhaus, Olga and Andersen, Louise B. and Kr{\"a}ker, Kristin and Polemiti, Elli and Jensen, Boye L. and J{\o}rgensen, Jan S. and Dechend, Ralf and Andersen, Marianne S.},
  title     = {Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight},
  series = {Journal of hypertension},
  volume    = {40},
  journal   = {Journal of hypertension},
  number    = {8},
  publisher = {Lippincott Williams \& Wilkins},
  address   = {Philadelphia},
  issn      = {0263-6352},
  doi       = {10.1097/HJH.0000000000003196},
  pages     = {1614 -- 1623},
  year      = {2022},
  abstract  = {Objective: Hypertension before and during early pregnancy has been associated with an increased risk of gestational diabetes mellitus (GDM) in retrospective analyses. We aimed to investigate the prospective blood pressure trackings in a population-based cohort of pregnant women, who were stratified according to their metabolic status in early third trimester. Methods: We recorded blood pressure longitudinally during pregnancy in 1230 women from the Odense Child Cohort, Denmark. Fasting glucose and insulin were measured at gestational weeks 28-30. Metabolic status was evaluated according to the WHO 2013 threshold for GDM (GDM-WHO: fasting plasma glucose >= 5.1 mmol/l), insulin and homeostatic model assessment of insulin resistance (HOMA-IR). Relationships between metabolic status in third trimester and blood pressure trajectories were evaluated with adjusted linear mixed models. Trajectory was defined as blood pressure records in pregnancy per 4 weeks interval. Results: Prevalence of GDM-WHO was 40\% (498/1230). GDM-WHO was associated with 1.46 (0.22-2.70) mmHg higher SBP and 1.04 (0.07-2.01) mmHg higher DBP trajectories in the overall cohort. The associations were driven by differences in the overweight group, with 3.14 (1.05-5.25) mmHg higher SBP and 1.94 (0.42-3.47) mmHg higher DBP per 4 weeks in women with GDM-WHO compared with women without GDM-WHO. GDM-WHO was not associated with blood pressure in women with normal weight. Blood pressure trajectories were elevated across quartiles of insulin resistance. Conclusion: GDM-WHO is associated with higher blood pressure in pregnancy, and there appears to be a stronger effect in overweight women.},
  language  = {en}
}
@article{ZechReichertEbnerPriemeretal.2022,
  author    = {Zech, Hilmar G. and Reichert, Markus and Ebner-Priemer, Ulrich W. and Tost, Heike and Rapp, Michael A. and Heinz, Andreas and Dolan, Raymond J. and Smolka, Michael N. and Deserno, Lorenz},
  title     = {Mobile data collection of cognitive-behavioral tasks in substance use disorders: Where are we now?},
  series = {Neuropsychobiology},
  volume    = {81},
  journal   = {Neuropsychobiology},
  number    = {5},
  publisher = {Karger},
  address   = {Basel},
  issn      = {0302-282X},
  doi       = {10.1159/000523697},
  pages     = {438 -- 450},
  year      = {2022},
  abstract  = {Introduction: Over the last decades, our understanding of the cognitive, motivational, and neural processes involved in addictive behavior has increased enormously. A plethora of laboratory-based and cross-sectional studies has linked cognitive-behavioral measures to between-subject differences in drinking behavior. However, such laboratory-based studies inevitably suffer from small sample sizes and the inability to link temporal fluctuations in task measures to fluctuations in real-life substance use. To overcome these problems, several existing behavioral tasks have been transferred to smartphones to allow studying cognition in the field. Method: In this narrative review, we first summarize studies that used existing behavioral tasks in the laboratory and self-reports of substance use with ecological momentary assessment (EMA) in the field. Next, we review studies on psychometric properties of smartphone-based behavioral tasks. Finally, we review studies that used both smartphone-based tasks and self-reports with EMA in the field. Results: Overall, studies were scarce and heterogenous both in tasks and in study outcomes. Nevertheless, existing findings are promising and point toward several methodological recommendations: concerning psychometrics, studies show that - although more systematic studies are necessary - task validity and reliability can be improved, for example, by analyzing several measurement sessions at once rather than analyzing sessions separately. Studies that use tasks in the field, moreover, show that power can be improved by choosing sampling schemes that combine time-based with event-based sampling, rather than relying on time-based sampling alone. Increasing sampling frequency can further increase power. However, as this also increases the burden to participants, more research is necessary to determine the ideal sampling frequency for each task. Conclusion: Although more research is necessary to systematically study both the psychometrics of smartphone-based tasks and the frequency at which task measures fluctuate, existing studies are promising and reveal important methodological recommendations useful for researchers interested in implementing behavioral tasks in EMA studies.},
  language  = {en}
}
@article{CiarnielloFulleRaponietal.2022,
  author    = {Ciarniello, Mauro and Fulle, Marco and Raponi, Andrea and Filacchione, Gianrico and Capaccioni, Fabrizio and Rotundi, Alessandra and Rinaldi, Giovanna and Formisano, Michelangelo and Magni, Gianfranco and Tosi, Federico and De Sanctis, Maria Cristina and Capria, Maria Teresa and Longobardo, Andrea and Beck, Pierre and Fornasier, Sonia and Kappel, David and Mennella, Vito and Mottola, Stefano and Rousseau, Batiste and Arnold, Gabriele},
  title     = {Macro and micro structures of pebble-made cometary nuclei reconciled by seasonal evolution},
  series = {Nature astronomy},
  volume    = {6},
  journal   = {Nature astronomy},
  number    = {5},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2397-3366},
  doi       = {10.1038/s41550-022-01625-y},
  pages     = {546 -- 553},
  year      = {2022},
  abstract  = {Comets evolve due to sublimation of ices embedded inside porous dust, triggering dust emission (that is, erosion) followed by mass loss, mass redistribution and surface modifications. Surface changes were revealed by the Deep Impact and Stardust NExT missions for comet 9P/Tempel 1 (ref.(1)), and a full inventory of the processes modifying cometary nuclei was provided by Rosetta while it escorted comet 67P/Churyumov-Gerasimenko for approximately two years(2-4). Such observations also showed puzzling water-ice-rich spots that stood out as patches optically brighter and spectrally bluer than the average cometary surfaces(5-9). These are up to tens of metres large and indicate macroscopic compositional dishomogeneities apparently in contrast with the structural homogeneity above centimetre scales of pebble-made nuclei(10). Here we show that the occurrence of blue patches determines the seasonal variability of the nucleus colour(4,11,12) and gives insight into the internal structure of comets. We define a new model that links the centimetre-sized pebbles composing the nucleus(10) and driving cometary activity(13,14) to metre-sized water-ice-enriched blocks embedded in a drier matrix. The emergence of blue patches is due to the matrix erosion driven by CO2-ice sublimation that exposes the water-ice-enriched blocks, which in turn are eroded by water-ice sublimation when exposed to sunlight. Our model explains the observed seasonal evolution of the nucleus and reconciles the available data at micro (sub-centimetre) and macro (metre) scales.},
  language  = {en}
}
@article{LichtKelsonBergeletal.2022,
  author    = {Licht, Alexis and Kelson, Julia and Bergel, Shelly J. and Schauer, Andrew J. and Petersen, Sierra Victoria and Capirala, Ashika and Huntington, Katharine W. and Dupont-Nivet, Guillaume and Win, Zaw and Aung, Day Wa},
  title     = {Dynamics of pedogenic carbonate growth in the tropical domain of Myanmar},
  series = {Geochemistry, geophysics, geosystems},
  volume    = {23},
  journal   = {Geochemistry, geophysics, geosystems},
  number    = {7},
  publisher = {American Geophysical Union},
  address   = {Washington},
  issn      = {1525-2027},
  doi       = {10.1029/2021GC009929},
  pages     = {15},
  year      = {2022},
  abstract  = {Pedogenic carbonate is widespread at mid latitudes where warm and dry conditions favor soil carbonate growth from spring to fall. The mechanisms and timing of pedogenic carbonate formation are more ambiguous in the tropical domain, where long periods of soil water saturation and high soil respiration enhance calcite dissolution. This paper provides stable carbon, oxygen and clumped isotope values from Quaternary and Miocene pedogenic carbonates in the tropical domain of Myanmar, in areas characterized by warm (>18°C) winters and annual rainfall up to 1,700 mm. We show that carbonate growth in Myanmar is delayed to the driest and coldest months of the year by sustained monsoonal rainfall from mid spring to late fall. The range of isotopic variability in Quaternary pedogenic carbonates can be solely explained by temporal changes of carbonate growth within the dry season, from winter to early spring. We propose that high soil moisture year-round in the tropical domain narrows carbonate growth to the driest months and makes it particularly sensitive to the seasonal distribution of rainfall. This sensitivity is also enabled by high winter temperatures, allowing carbonate growth to occur outside the warmest months of the year. This high sensitivity is expected to be more prominent in the geological record during times with higher temperatures and greater expansion of the tropical realm. Clumped isotope temperatures, δ13C and δ18O values of tropical pedogenic carbonates are impacted by changes of both rainfall seasonality and surface temperatures; this sensitivity can potentially be used to track past tropical rainfall distribution.},
  language  = {en}
}
@article{VandenWyngaertGanzertSetoetal.2022,
  author    = {Van den Wyngaert, Silke and Ganzert, Lars and Seto, Kensuke and Rojas-Jimenez, Keilor and Agha, Ramsy and Berger, Stella A. and Woodhouse, Jason and Padisak, Judit and Wurzbacher, Christian and Kagami, Maiko and Grossart, Hans-Peter},
  title     = {Seasonality of parasitic and saprotrophic zoosporic fungi: linking sequence data to ecological traits},
  series = {ISME journal},
  volume    = {16},
  journal   = {ISME journal},
  number    = {9},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {1751-7362},
  doi       = {10.1038/s41396-022-01267-y},
  pages     = {2242 -- 2254},
  year      = {2022},
  abstract  = {Zoosporic fungi of the phylum Chytridiomycota (chytrids) regularly dominate pelagic fungal communities in freshwater and marine environments. Their lifestyles range from obligate parasites to saprophytes. Yet, linking the scarce available sequence data to specific ecological traits or their host ranges constitutes currently a major challenge. We combined 28 S rRNA gene amplicon sequencing with targeted isolation and sequencing approaches, along with cross-infection assays and analysis of chytrid infection prevalence to obtain new insights into chytrid diversity, ecology, and seasonal dynamics in a temperate lake. Parasitic phytoplankton-chytrid and saprotrophic pollen-chytrid interactions made up the majority of zoosporic fungal reads. We explicitly demonstrate the recurrent dominance of parasitic chytrids during frequent diatom blooms and saprotrophic chytrids during pollen rains. Distinct temporal dynamics of diatom-specific parasitic clades suggest mechanisms of coexistence based on niche differentiation and competitive strategies. The molecular and ecological information on chytrids generated in this study will aid further exploration of their spatial and temporal distribution patterns worldwide. To fully exploit the power of environmental sequencing for studies on chytrid ecology and evolution, we emphasize the need to intensify current isolation efforts of chytrids and integrate taxonomic and autecological data into long-term studies and experiments.},
  language  = {en}
}
@article{DresslerChiasseriniFitzeketal.2022,
  author    = {Dressler, Falko and Chiasserini, Carla Fabiana and Fitzek, Frank H. P. and Karl, Holger and Cigno, Renato Lo and Capone, Antonio and Casetti, Claudio and Malandrino, Francesco and Mancuso, Vincenzo and Klingler, Florian and Rizzo, Gianluca},
  title     = {V-Edge},
  series = {IEEE network},
  volume    = {36},
  journal   = {IEEE network},
  number    = {3},
  publisher = {Inst. of Electr. and Electronics Engineers},
  address   = {Piscataway},
  issn      = {0890-8044},
  doi       = {10.1109/MNET.001.2100491},
  pages     = {24 -- 31},
  year      = {2022},
  abstract  = {As we move from 5G to 6G, edge computing is one of the concepts that needs revisiting. Its core idea is still intriguing: Instead of sending all data and tasks from an end user's device to the cloud, possibly covering thousands of kilometers and introducing delays lower-bounded by propagation speed, edge servers deployed in close proximity to the user (e.g., at some base station) serve as proxy for the cloud. This is particularly interesting for upcoming machine-learning-based intelligent services, which require substantial computational and networking performance for continuous model training. However, this promising idea is hampered by the limited number of such edge servers. In this article, we discuss a way forward, namely the V-Edge concept. V-Edge helps bridge the gap between cloud, edge, and fog by virtualizing all available resources including the end users' devices and making these resources widely available. Thus, V-Edge acts as an enabler for novel microservices as well as cooperative computing solutions in next-generation networks. We introduce the general V-Edge architecture, and we characterize some of the key research challenges to overcome in order to enable wide-spread and intelligent edge services.},
  language  = {en}
}
@article{GischRobertBerlinetal.2022,
  author    = {Gisch, Ulrike Alexandra and Robert, Margaux and Berlin, Noemi and Nebout, Antoine and Etile, Fabrice and Teyssier, Sabrina and Andreeva, Valentina A. and Hercberg, Serge and Touvier, Mathilde and Peneau, Sandrine},
  title     = {Mastery is associated with weight status, food intake, snacking, and eating disorder symptoms in the NutriNet-Sante cohort study},
  series = {Frontiers in Nutrition},
  volume    = {9},
  journal   = {Frontiers in Nutrition},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-861X},
  doi       = {10.3389/fnut.2022.871669},
  pages     = {13},
  year      = {2022},
  abstract  = {Mastery is a psychological resource that is defined as the extent to which individuals perceive having control over important circumstances of their lives. Although mastery has been associated with various physical and psychological health outcomes, studies assessing its relationship with weight status and dietary behavior are lacking. The aim of this cross-sectional study was to assess the relationship between mastery and weight status, food intake, snacking, and eating disorder (ED) symptoms in the NutriNet-Sante cohort study. Mastery was measured with the Pearlin Mastery Scale (PMS) in 32,588 adults (77.45\% female), the mean age was 50.04 (14.53) years. Height and weight were self-reported. Overall diet quality and food group consumption were evaluated with >= 3 self-reported 24-h dietary records (range: 3-27). Snacking was assessed with an ad-hoc question. ED symptoms were assessed with the Sick-Control-One-Fat-Food Questionnaire (SCOFF). Linear and logistic regression analyses were conducted to assess the relationship between mastery and weight status, food intake, snacking, and ED symptoms, controlling for sociodemographic and lifestyle characteristics. Females with a higher level of mastery were less likely to be underweight (OR: 0.88; 95\%CI: 0.84, 0.93), overweight [OR: 0.94 (0.91, 0.97)], or obese [class I: OR: 0.86 (0.82, 0.90); class II: OR: 0.76 (0.71, 0.82); class III: OR: 0.77 (0.69, 0.86)]. Males with a higher level of mastery were less likely to be obese [class III: OR: 0.75 (0.57, 0.99)]. Mastery was associated with better diet quality overall, a higher consumption of fruit and vegetables, seafood, wholegrain foods, legumes, non-salted oleaginous fruits, and alcoholic beverages and with a lower consumption of meat and poultry, dairy products, sugary and fatty products, milk-based desserts, and sweetened beverages. Mastery was also associated with lower snacking frequency [OR: 0.89 (0.86, 0.91)] and less ED symptoms [OR: 0.73 (0.71, 0.75)]. As mastery was associated with favorable dietary behavior and weight status, targeting mastery might be a promising approach in promoting healthy behaviors.},
  language  = {en}
}
@article{BelluardoScherzSantosetal.2022,
  author    = {Belluardo, Francesco and Scherz, Mark D. and Santos, Barbara and Andreone, Franco and Antonelli, Alexandre and Glaw, Frank and Munoz-Pajares, A. Jesus and Randrianirina, Jasmin E. and Raselimanana, Achille P. and Vences, Miguel and Crottini, Angelica},
  title     = {Molecular taxonomic identification and species-level phylogeny of the narrow-mouthed frogs of the genus Rhombophryne (Anura: Microhylidae: Cophylinae) from Madagascar},
  series = {Systematics and biodiversity},
  volume    = {20},
  journal   = {Systematics and biodiversity},
  number    = {1},
  publisher = {Routledge, Taylor \& Francis Group},
  address   = {Abingdon},
  issn      = {1477-2000},
  doi       = {10.1080/14772000.2022.2039320},
  pages     = {1 -- 13},
  year      = {2022},
  abstract  = {The study of diamond frogs (genus Rhombophryne, endemic to Madagascar) has been historically hampered by the paucity of available specimens, because of their low detectability in the field. Over the last 10 years, 13 new taxa have been described, and 20 named species are currently recognized. Nevertheless, undescribed diversity within the genus is probably large, calling for a revision of the taxonomic identification of published records and an update of the known distribution of each lineage. Here we generate DNA sequences of the mitochondrial 16S rRNA gene of all specimens available to us, revise the genetic data from public databases, and report all deeply divergent mitochondrial lineages of Rhombophryne identifiable from these data. We also generate a multi-locus dataset (including five mitochondrial and eight nuclear markers; 9844 bp) to infer a species-level phylogenetic hypothesis for the diversification of this genus and revise the distribution of each lineage. We recognize a total of 10 candidate species, two of which are identified here for the first time. The genus Rhombophryne is here proposed to be divided into six main species groups, and phylogenetic relationships among some of them are not fully resolved. These frogs are primarily distributed in northern Madagascar, and most species are known from only few localities. A previous record of this genus from the Tsingy de Bemaraha (western Madagascar) is interpreted as probably due to a mislabelling and should not be considered further unless confirmed by new data. By generating this phylogenetic hypothesis and providing an updated distribution of each lineage, our findings will facilitate future species descriptions, pave the way for evolutionary studies, and provide valuable information for the urgent conservation of diamond frogs.},
  language  = {en}
}
@article{NitzscheKleebergHoffmannetal.2022,
  author    = {Nitzsche, Kai Nils and Kleeberg, Andreas and Hoffmann, Carsten and Merz, Christoph and Premke, Katrin and Gessler, Arthur and Sommer, Michael and Kayler, Zachary E.},
  title     = {Kettle holes reflect the biogeochemical characteristics of their catchment area and the intensity of the element-specific input},
  series = {Journal of soils and sediments : protection, risk assessment and remediation},
  volume    = {22},
  journal   = {Journal of soils and sediments : protection, risk assessment and remediation},
  number    = {3},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {1439-0108},
  doi       = {10.1007/s11368-022-03145-8},
  pages     = {994 -- 1009},
  year      = {2022},
  abstract  = {Purpose Kettle holes are small inland water bodies known to be dominated by terrigenous material; however, the processes and structures that drive the enrichment and depletion of specific geochemical elements in the water column and kettle hole sediment remain unclear. We hypothesized that the mobile elements (Ca, Fe, K, P) behave different from each other in their transport, intermediate soil retention, and final accumulation in the kettle hole sediment. Methods Topsoils from transects spanning topographic positions from erosional to depositional areas, sediment cores, shallow groundwater, and kettle hole water of two glacial kettle holes in NE Germany (Rittgarten (RG) and Kraatz (KR)) were collected. The Fe, Ca, K, and total P (TP) concentrations were quantified and additionally the major anions in shallow groundwater and kettle hole water. The element-specific mobilization, relocation, and, finally, accumulation in the sediment were investigated by enrichment factors. Furthermore, a piper diagram was used to estimate groundwater flow directions and pond-internal processes. Results At KR only, the upper 10 cm of the kettle hole sediment reflected the relative element composition of the eroded terrestrial soils. The sediment from both kettle holes was enriched in Ca, Fe, K, and P compared to topsoils, indicating several possible processes including the input of clay and silt sized particles enriched in these elements, fertilizer input, and pond-internal processes including biogenic calcite and hydroxyapatite precipitation, Fe-P binding (KR), FeSx formation (RG), and elemental fixation and deposition via floating macrophytes (RG). High Ca concentrations in the kettle hole water indicated a high input of Ca from shallow groundwater inflow, while Ca precipitation in the kettle hole water led to lower Ca concentration in groundwater outflow. Conclusions The considerable element losses in the surrounding soils and the inputs into the kettle holes should be addressed by comprehensive soil and water protection measures, i.e., avoiding tillage, fertilizing conservatively, and creating buffer zones.},
  language  = {en}
}
@article{GarbulowskiSmolinskaCabuketal.2022,
  author    = {Garbulowski, Mateusz and Smolinska, Karolina and {\c{C}}abuk, Uğur and Yones, Sara A. and Celli, Ludovica and Yaz, Esma Nur and Barrenas, Fredrik and Diamanti, Klev and Wadelius, Claes and Komorowski, Jan},
  title     = {Machine learning-based analysis of glioma grades reveals co-enrichment},
  series = {Cancers},
  volume    = {14},
  journal   = {Cancers},
  number    = {4},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-6694},
  doi       = {10.3390/cancers14041014},
  pages     = {19},
  year      = {2022},
  abstract  = {Simple Summary Gliomas are heterogenous types of cancer, therefore the therapy should be personalized and targeted toward specific pathways. We developed a methodology that corrected strong batch effects from The Cancer Genome Atlas datasets and estimated glioma grade-specific co-enrichment mechanisms using machine learning. Our findings created hypotheses for annotations, e.g., pathways, that should be considered as therapeutic targets. Gliomas develop and grow in the brain and central nervous system. Examining glioma grading processes is valuable for improving therapeutic challenges. One of the most extensive repositories storing transcriptomics data for gliomas is The Cancer Genome Atlas (TCGA). However, such big cohorts should be processed with caution and evaluated thoroughly as they can contain batch and other effects. Furthermore, biological mechanisms of cancer contain interactions among biomarkers. Thus, we applied an interpretable machine learning approach to discover such relationships. This type of transparent learning provides not only good predictability, but also reveals co-predictive mechanisms among features. In this study, we corrected the strong and confounded batch effect in the TCGA glioma data. We further used the corrected datasets to perform comprehensive machine learning analysis applied on single-sample gene set enrichment scores using collections from the Molecular Signature Database. Furthermore, using rule-based classifiers, we displayed networks of co-enrichment related to glioma grades. Moreover, we validated our results using the external glioma cohorts. We believe that utilizing corrected glioma cohorts from TCGA may improve the application and validation of any future studies. Finally, the co-enrichment and survival analysis provided detailed explanations for glioma progression and consequently, it should support the targeted treatment.},
  language  = {en}
}
@article{KupferBauervanRoesteletal.2022,
  author    = {Kupfer, Thomas and Bauer, Evan B. and van Roestel, Jan and Bellm, Eric C. and Bildsten, Lars and Fuller, Jim and Prince, Thomas A. and Heber, Ulrich and Geier, Stephan and Green, Matthew J. and Kulkarni, Shrinivas R. and Bloemen, Steven and Laher, Russ R. and Rusholme, Ben and Schneider, David},
  title     = {Discovery of a Double-detonation Thermonuclear Supernova Progenitor},
  series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters},
  volume    = {925},
  journal   = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters},
  number    = {2},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {2041-8205},
  doi       = {10.3847/2041-8213/ac48f1},
  pages     = {10},
  year      = {2022},
  abstract  = {We present the discovery of a new double-detonation progenitor system consisting of a hot subdwarf B (sdB) binary with a white dwarf companion with a P (orb) = 76.34179(2) minutes orbital period. Spectroscopic observations are consistent with an sdB star during helium core burning residing on the extreme horizontal branch. Chimera light curves are dominated by ellipsoidal deformation of the sdB star and a weak eclipse of the companion white dwarf. Combining spectroscopic and light curve fits, we find a low-mass sdB star, M (sdB) = 0.383 +/- 0.028 M (circle dot) with a massive white dwarf companion, M (WD) = 0.725 +/- 0.026 M (circle dot). From the eclipses we find a blackbody temperature for the white dwarf of 26,800 K resulting in a cooling age of approximate to 25 Myr whereas our MESA model predicts an sdB age of approximate to 170 Myr. We conclude that the sdB formed first through stable mass transfer followed by a common envelope which led to the formation of the white dwarf companion approximate to 25 Myr ago. Using the MESA stellar evolutionary code we find that the sdB star will start mass transfer in approximate to 6 Myr and in approximate to 60 Myr the white dwarf will reach a total mass of 0.92 M (circle dot) with a thick helium layer of 0.17 M (circle dot). This will lead to a detonation that will likely destroy the white dwarf in a peculiar thermonuclear supernova. PTF1 J2238+7430 is only the second confirmed candidate for a double-detonation thermonuclear supernova. Using both systems we estimate that at least approximate to 1\% of white dwarf thermonuclear supernovae originate from sdB+WD binaries with thick helium layers, consistent with the small number of observed peculiar thermonuclear explosions.},
  language  = {en}
}
@article{NajmanSobelMillaretal.2022,
  author    = {Najman, Yani and Sobel, Edward and Millar, Ian and Luan, Xiwu and Zapata, Sebastian and Garzanti, Eduardo and Parra, Mauricio and Vezzoli, Giovanni and Zhang, Peng and Wa Aung, Day and Paw, Saw Mu Tha Lay and Lwin, Thae Naung},
  title     = {The timing of collision between Asia and the West Burma Terrane, and the development of the Indo-Burman Ranges},
  series = {Tectonics},
  volume    = {41},
  journal   = {Tectonics},
  number    = {7},
  publisher = {American Geophysical Union},
  address   = {Washington},
  issn      = {0278-7407},
  doi       = {10.1029/2021TC007057},
  pages     = {22},
  year      = {2022},
  abstract  = {The West Burma Terrane (WBT) is a small terrane bounded to the east by the Asian Sibumasu Block and to the west by the Indo-Burman Ranges (IBR), the latter being an exhumed accretionary prism that formed during subduction of Indian oceanic lithosphere beneath Asia. Understanding the geological history of the WBT is important for reconstruction of the closure history of the Tethys Ocean and India-Asia collision. Currently there are major discrepancies in the proposed timings of collision between the WBT with both India and Asia; whether the WBT collided with India or Asia first is debated, and proposed timings of collisions stretch from the Mesozoic to the Cenozoic. We undertook a multi-technique provenance study involving petrography, detrital zircon U-Pb and Hf analyses, rutile U-Pb analyses and Sr-Nd bulk rock analyses on sediments of the Central Myanmar Basins of the WBT. We determined that the first arrival of Asian material into the basin occurred after the earliest late Eocene and by the early Oligocene, thus placing a minimum constraint on the timing of WBT-Asia collision. Our low temperature thermochronological study of the IBR records two periods of exhumation, in the early-middle Eocene, and at the Oligo-Miocene boundary. The Eocene event may be associated with the collision of the WBT with India. The later event at the Oligo-Miocene boundary may be associated with changes in wedge dynamics resulting from increased sediment supply to the system; however a number of other possible causes provide equally plausible explanations for both events.},
  language  = {en}
}
@article{JebabliZouhalBoullosaetal.2022,
  author    = {Jebabli, Nidhal and Zouhal, Hassane and Boullosa, Daniel and Govindasamy, Karuppasamy and Tourny, Claire and Hackney, Anthony C. and Granacher, Urs and Ben Abderrahman, Abderraouf},
  title     = {The effects of preferred music and its timing on performance, pacing, and psychophysiological responses during the 6-min test},
  series = {Journal of human kinetics},
  volume    = {82},
  journal   = {Journal of human kinetics},
  number    = {1},
  publisher = {Academy of Physical Education},
  address   = {Katowice},
  issn      = {1640-5544},
  doi       = {10.2478/hukin-2022-0038},
  pages     = {123 -- 133},
  year      = {2022},
  abstract  = {The aim of this study was to investigate the effects of listening to preferred music during a warm up or exercise, on performance during a 6-min all-out exercise test (6-MT) in young adult males. Twenty-five healthy males volunteered to participate in this study. Following a within subject design, participants performed three test conditions (MDT: music during the test; MDW: music during the warm-up; WM: without music) in random order. Outcomes included mean running speed over the 6-min test (MRS6), total distance covered (TDC), heart rate responses (HRpeak, HRmean), blood lactate (3-min after the test), and the rating of perceived exertion (RPE); additionally, feeling scale scores were recorded. Listening to preferred music during running resulted in significant TDC (Delta up arrow 10\%, p=0.006, ES=0.80) and MRS6 (Delta up arrow 14\%, p=0.012, ES=1.02) improvement during the 6-MT, improvement was also noted for the warm-up with music condition (TDC:Delta up arrow 8\%, p=0.028, ES=0.63; MRS6:Delta up arrow 8\%, p=0.032, ES=0.61). A similar reverse "J-shaped" pacing profile was detected during the three conditions. Blood lactate was lower in the MDT condition by 8\% (p=0.01, ES=1.10), but not the MDW condition, compared to MW. In addition, no statistically significant differences were found between the test sessions for the HR, RPE, and feeling scale scores. In conclusion, listening to music during exercise testing would be more beneficial for optimal TDC and MRS6 performances compared to MDW and WM.},
  language  = {en}
}
@article{NumbergerZoccaratoWoodhouseetal.2022,
  author    = {Numberger, Daniela and Zoccarato, Luca and Woodhouse, Jason Nicholas and Ganzert, Lars and Sauer, Sascha and Garc{\´i}a M{\´a}rquez, Jaime Ricardo and Domisch, Sami and Grossart, Hans-Peter and Greenwood, Alex},
  title     = {Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens},
  series = {The science of the total environment : an international journal for scientific research into the environment and its relationship with man},
  volume    = {845},
  journal   = {The science of the total environment : an international journal for scientific research into the environment and its relationship with man},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0048-9697},
  doi       = {10.1016/j.scitotenv.2022.157321},
  pages     = {13},
  year      = {2022},
  abstract  = {Freshwater ecosystems are characterized by complex and highly dynamic microbial communities that are strongly structured by their local environment and biota. Accelerating urbanization and growing city populations detrimentally alter freshwater environments. To determine differences in freshwater microbial communities associated with urban-ization, full-length 16S rRNA gene PacBio sequencing was performed in a case study from surface waters and sedi-ments from a wastewater treatment plant, urban and rural lakes in the Berlin-Brandenburg region, Northeast Germany. Water samples exhibited highly habitat specific bacterial communities with multiple genera showing clear urban signatures. We identified potentially harmful bacterial groups associated with environmental parameters specific to urban habitats such as Alistipes, Escherichia/Shigella, Rickettsia and Streptococcus. We demonstrate that urban-ization alters natural microbial communities in lakes and, via simultaneous warming and eutrophication and creates favourable conditions that promote specific bacterial genera including potential pathogens. Our findings are evidence to suggest an increased potential for long-term health risk in urbanized waterbodies, at a time of rapidly expanding global urbanization. The results highlight the urgency for undertaking mitigation measures such as targeted lake restoration projects and sustainable water management efforts.},
  language  = {en}
}
@article{BotteriPeveriBerstadetal.2022,
  author    = {Botteri, Edoardo and Peveri, Giulia and Berstad, Paula and Bagnardi, Vincenzo and Chen, Sairah L. F. and Sandanger, Torkjel M. and Hoff, Geir and Dahm, Christina C. and Antoniussen, Christian S. and Tjonneland, Anne and Eriksen, Anne Kirstine and Skeie, Guri and Perez-Cornago, Aurora and Huerta, Jose Maria and Jakszyn, Paula and Harlid, Sophia and Sundstroem, Bjoern and Barricarte, Aurelio and Monninkhof, Evelyn M. and Derksen, Jeroen W. G. and Schulze, Matthias Bernd and Bueno-de-Mesquita, Bas and Sanchez, Maria-Jose and Cross, Amanda J. and Tsilidis, Konstantinos K. and De Magistris, Maria Santucci and Kaaks, Rudolf and Katzke, Verena and Rothwell, Joseph A. and Laouali, Nasser and Severi, Gianluca and Amiano, Pilar and Contiero, Paolo and Sacerdote, Carlotta and Goldberg, Marcel and Touvier, Mathilde and Freisling, Heinz and Viallon, Vivian and Weiderpass, Elisabete and Riboli, Elio and Gunter, Marc J. and Jenab, Mazda and Ferrari, Pietro},
  title     = {Changes in lifestyle and risk of colorectal cancer in the European prospective investigation into cancer and nutrition},
  series = {The American journal of gastroenterology : AJG},
  volume    = {118},
  journal   = {The American journal of gastroenterology : AJG},
  number    = {4},
  publisher = {Lippincott Williams \& Wilkins},
  address   = {Philadelphia},
  issn      = {0002-9270},
  doi       = {10.14309/ajg.0000000000002065},
  pages     = {702 -- 711},
  year      = {2022},
  abstract  = {INTRODUCTION: We investigated the impact of changes in lifestyle habits on colorectal cancer (CRC) risk in a multicountry European cohort. METHODS: We used baseline and follow-up questionnaire data from the European Prospective Investigation into Cancer cohort to assess changes in lifestyle habits and their associations with CRC development. We calculated a healthy lifestyle index (HLI) score based on smoking status, alcohol consumption, body mass index, and physical activity collected at the 2 time points. HLI ranged from 0 (most unfavorable) to 16 (most favorable). We estimated the association between HLI changes and CRC risk using Cox regression models and reported hazard ratios (HR) with 95\% confidence intervals (CI). RESULTS: Among 295,865 participants, 2,799 CRC cases were observed over a median of 7.8 years. The median time between questionnaires was 5.7 years. Each unit increase in HLI from the baseline to the follow-up assessment was associated with a statistically significant 3\% lower CRC risk. Among participants in the top tertile at baseline (HLI > 11), those in the bottom tertile at follow-up (HLI <= 9) had a higher CRC risk (HR 1.34; 95\% CI 1.02-1.75) than those remaining in the top tertile. Among individuals in the bottom tertile at baseline, those in the top tertile at follow-up had a lower risk (HR 0.77; 95\% CI 0.59-1.00) than those remaining in the bottom tertile. DISCUSSION: Improving adherence to a healthy lifestyle was inversely associated with CRC risk, while worsening adherence was positively associated with CRC risk. These results justify and support recommendations for healthy lifestyle changes and healthy lifestyle maintenance for CRC prevention.},
  language  = {en}
}
@article{ToumoulinTardifBecquetDonnadieuetal.2022,
  author    = {Toumoulin, Agathe and Tardif-Becquet, Delphine and Donnadieu, Yannick and Licht, Alexis and Ladant, Jean-Baptiste and Kunzmann, Lutz and Dupont-Nivet, Guillaume},
  title     = {Evolution of continental temperature seasonality from the Eocene greenhouse to the Oligocene icehouse},
  series = {Climate of the past : an interactive open access journal of the European Geosciences Union},
  volume    = {18},
  journal   = {Climate of the past : an interactive open access journal of the European Geosciences Union},
  number    = {2},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1814-9324},
  doi       = {10.5194/cp-18-341-2022},
  pages     = {341 -- 362},
  year      = {2022},
  abstract  = {At the junction of greenhouse and icehouse climate states, the Eocene-Oligocene Transition (EOT) is a key moment in Cenozoic climate history. While it is associated with severe extinctions and biodiversity turnovers on land, the role of terrestrial climate evolution remains poorly resolved, especially the associated changes in seasonality. Some paleobotanical and geochemical continental records in parts of the Northern Hemisphere suggest the EOT is associated with a marked cooling in winter, leading to the development of more pronounced seasons (i.e., an increase in the mean annual range of temperature, MATR). However, the MATR increase has been barely studied by climate models and large uncertainties remain on its origin, geographical extent and impact. In order to better understand and describe temperature seasonality changes between the middle Eocene and the early Oligocene, we use the Earth system model IPSL-CM5A2 and a set of simulations reconstructing the EOT through three major climate forcings: pCO(2) decrease (1120, 840 and 560 ppm), the Antarctic ice-sheet (AIS) formation and the associated sea-level decrease. Our simulations suggest that pCO(2) lowering alone is not sufficient to explain the seasonality evolution described by the data through the EOT but rather that the combined effects of pCO(2) , AIS formation and increased continentality provide the best data-model agreement.pCO(2) decrease induces a zonal pattern with alternating increasing and decreasing seasonality bands particularly strong in the northern high latitudes (up to 8 degrees C MATR increase) due to sea-ice and surface albedo feedback. Conversely, the onset of the AIS is responsible for a more constant surface albedo yearly, which leads to a strong decrease in seasonality in the southern midlatitudes to high latitudes (> 40 degrees S). Finally, continental areas that emerged due to the sea-level lowering cause the largest increase in seasonality and explain most of the global heterogeneity in MATR changes (1MATR) patterns. The Delta MATR patterns we reconstruct are generally consistent with the variability of the EOT biotic crisis intensity across the Northern Hemisphere and provide insights on their underlying mechanisms.},
  language  = {en}
}
@article{SchwopePiresKurpasetal.2022,
  author    = {Schwope, Axel and Pires, Adriana M. and Kurpas, Jan and Doroshenko, Victor and Suleimanov, Valery F. and Freyberg, Michael and Becker, Werner and Dennerl, Konrad and Haberl, Frank and Lamer, Georg and Maitra, Chandreyee and Potekhin, Alexander Y. and Ramos-Ceja, Miriam E. and Santangelo, Andrea and Traulsen, Iris and Werner, Klaus},
  title     = {Phase-resolved X-ray spectroscopy of PSR B0656+14 with SRG/eROSITA and XMM-Newton},
  series = {Astronomy and astrophysics : an international weekly journal},
  volume    = {661},
  journal   = {Astronomy and astrophysics : an international weekly journal},
  publisher = {EDP Sciences},
  address   = {Les Ulis},
  issn      = {0004-6361},
  doi       = {10.1051/0004-6361/202141105},
  pages     = {21},
  year      = {2022},
  abstract  = {We present a detailed spectroscopic and timing analysis of X-ray observations of the bright pulsar PSR B0656+14. The observations were obtained simultaneously with eROSITA and XMM-Newton during the calibration and performance verification phase of the Spektrum-Roentgen-Gamma mission (SRG). The analysis of the 100 ks deep observation of eROSITA is supported by archival observations of the source, including XMM-Newton, NuSTAR, and NICER. Using XMM-Newton and NICER, we first established an X-ray ephemeris for the time interval 2015 to 2020, which connects all X-ray observations in this period without cycle count alias and phase shifts. The mean eROSITA spectrum clearly reveals an absorption feature originating from the star at 570 eV with a Gaussian sigma of about 70 eV that was tentatively identified in a previous long XMM-Newton observation. A second previously discussed absorption feature occurs at 260-265 eV and is described here as an absorption edge. It could be of atmospheric or of instrumental origin. These absorption features are superposed on various emission components that are phenomenologically described here as the sum of hot (120 eV) and cold (65 eV) blackbody components, both of photospheric origin, and a power law with photon index Gamma = 2 from the magnetosphere. We created energy-dependent light curves and phase-resolved spectra with a high signal-to-noise ratio. The phase-resolved spectroscopy reveals that the Gaussian absorption line at 570 eV is clearly present throughout similar to 60\% of the spin cycle, but it is otherwise undetected. Likewise, its parameters were found to be dependent on phase. The visibility of the line strength coincides in phase with the maximum flux of the hot blackbody. If the line originates from the stellar surface, it nevertheless likely originates from a different location than the hot polar cap. We also present three families of model atmospheres: a magnetized atmosphere, a condensed surface, and a mixed model. They were applied to the mean observed spectrum, whose continuum fit the observed data well. The atmosphere model, however, predicts distances that are too short. For the mixed model, the Gaussian absorption may be interpreted as proton cyclotron absorption in a field as high as 10(14) G, which is significantly higher than the field derived from the moderate observed spin-down.},
  language  = {en}
}
@article{WarbyZuZeiskeetal.2022,
  author    = {Warby, Jonathan and Zu, Fengshuo and Zeiske, Stefan and Gutierrez-Partida, Emilio and Frohloff, Lennart and Kahmann, Simon and Frohna, Kyle and Mosconi, Edoardo and Radicchi, Eros and Lang, Felix and Shah, Sahil and Pena-Camargo, Francisco and Hempel, Hannes and Unold, Thomas and Koch, Norbert and Armin, Ardalan and De Angelis, Filippo and Stranks, Samuel D. and Neher, Dieter and Stolterfoht, Martin},
  title     = {Understanding performance limiting interfacial recombination in pin Perovskite solar cells},
  series = {Advanced energy materials},
  volume    = {12},
  journal   = {Advanced energy materials},
  number    = {12},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1614-6832},
  doi       = {10.1002/aenm.202103567},
  pages     = {10},
  year      = {2022},
  abstract  = {Perovskite semiconductors are an attractive option to overcome the limitations of established silicon based photovoltaic (PV) technologies due to their exceptional opto-electronic properties and their successful integration into multijunction cells. However, the performance of single- and multijunction cells is largely limited by significant nonradiative recombination at the perovskite/organic electron transport layer junctions. In this work, the cause of interfacial recombination at the perovskite/C-60 interface is revealed via a combination of photoluminescence, photoelectron spectroscopy, and first-principle numerical simulations. It is found that the most significant contribution to the total C-60-induced recombination loss occurs within the first monolayer of C-60, rather than in the bulk of C-60 or at the perovskite surface. The experiments show that the C-60 molecules act as deep trap states when in direct contact with the perovskite. It is further demonstrated that by reducing the surface coverage of C-60, the radiative efficiency of the bare perovskite layer can be retained. The findings of this work pave the way toward overcoming one of the most critical remaining performance losses in perovskite solar cells.},
  language  = {en}
}
@article{ShamsWangRoineetal.2022,
  author    = {Shams, Boshra and Wang, Ziqian and Roine, Timo and Aydogan, Dogu Baran and Vajkoczy, Peter and Lippert, Christoph and Picht, Thomas and Fekonja, Lucius Samo},
  title     = {Machine learning-based prediction of motor status in glioma patients using diffusion MRI metrics along the corticospinal tract},
  series = {Brain communications},
  volume    = {4},
  journal   = {Brain communications},
  number    = {3},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {2632-1297},
  doi       = {10.1093/braincomms/fcac141},
  pages     = {17},
  year      = {2022},
  abstract  = {Shams et al. report that glioma patients' motor status is predicted accurately by diffusion MRI metrics along the corticospinal tract based on support vector machine method, reaching an overall accuracy of 77\%. They show that these metrics are more effective than demographic and clinical variables. Along tract statistics enables white matter characterization using various diffusion MRI metrics. These diffusion models reveal detailed insights into white matter microstructural changes with development, pathology and function. Here, we aim at assessing the clinical utility of diffusion MRI metrics along the corticospinal tract, investigating whether motor glioma patients can be classified with respect to their motor status. We retrospectively included 116 brain tumour patients suffering from either left or right supratentorial, unilateral World Health Organization Grades II, III and IV gliomas with a mean age of 53.51 +/- 16.32 years. Around 37\% of patients presented with preoperative motor function deficits according to the Medical Research Council scale. At group level comparison, the highest non-overlapping diffusion MRI differences were detected in the superior portion of the tracts' profiles. Fractional anisotropy and fibre density decrease, apparent diffusion coefficient axial diffusivity and radial diffusivity increase. To predict motor deficits, we developed a method based on a support vector machine using histogram-based features of diffusion MRI tract profiles (e.g. mean, standard deviation, kurtosis and skewness), following a recursive feature elimination method. Our model achieved high performance (74\% sensitivity, 75\% specificity, 74\% overall accuracy and 77\% area under the curve). We found that apparent diffusion coefficient, fractional anisotropy and radial diffusivity contributed more than other features to the model. Incorporating the patient demographics and clinical features such as age, tumour World Health Organization grade, tumour location, gender and resting motor threshold did not affect the model's performance, revealing that these features were not as effective as microstructural measures. These results shed light on the potential patterns of tumour-related microstructural white matter changes in the prediction of functional deficits.},
  language  = {en}
}
@article{RepaschScheingrossHoviusetal.2022,
  author    = {Repasch, Marisa and Scheingross, Joel S. and Hovius, Niels and Vieth-Hillebrand, Andrea and Mueller, Carsten W. and H{\"o}schen, Carmen and Szupiany, Ricardo N. and Sachse, Dirk},
  title     = {River organic carbon fluxes modulated by hydrodynamic sorting of particulate organic matter},
  series = {Geophysical research letters},
  volume    = {49},
  journal   = {Geophysical research letters},
  number    = {3},
  publisher = {American Geophysical Union},
  address   = {Washington},
  issn      = {0094-8276},
  doi       = {10.1029/2021GL096343},
  pages     = {11},
  year      = {2022},
  abstract  = {Rivers regulate the global carbon cycle by transferring particulate organic carbon (POC) from terrestrial landscapes to marine sedimentary basins, but the processes controlling the amount and composition of fluvially exported POC are poorly understood. We propose that hydrodynamic sorting processes modify POC fluxes during fluvial transit. We test this hypothesis by studying POC transported along a similar to 1,200 km reach of the Rio Bermejo, Argentina. Nanoscale secondary ion mass spectrometry revealed that POC was either fine, mineral-associated organic matter, or coarse discrete organic particles. Mineral-associated POC is more resistant to oxidation and has a lower particle settling velocity than discrete POC. Consequently, hydraulic sorting and downstream fining amplify the proportion of fine, mineral-associated POC from similar to 55\% to similar to 78\% over 1,220 km of downstream transit. This suggests that mineral-associated POC has a greater probability of export and preservation in marine basins than plant detritus, which may be oxidized to CO2 during transit.},
  language  = {en}
}
@article{SeboldChenOenaletal.2022,
  author    = {Sebold, Miriam and Chen, Hao and {\"O}nal, Aleyna and Kuitunen-Paul, S{\"o}ren and Mojtahedzadeh, Negin and Garbusow, Maria and Nebe, Stephan and Wittchen, Hans-Ulrich and Huys, Quentin J. M. and Schlagenhauf, Florian and Rapp, Michael A. and Smolka, Michael N. and Heinz, Andreas},
  title     = {Stronger prejudices are associated with decreased model-based control},
  series = {Frontiers in psychology},
  volume    = {12},
  journal   = {Frontiers in psychology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2021.767022},
  pages     = {10},
  year      = {2022},
  abstract  = {Background: Prejudices against minorities can be understood as habitually negative evaluations that are kept in spite of evidence to the contrary. Therefore, individuals with strong prejudices might be dominated by habitual or "automatic" reactions at the expense of more controlled reactions. Computational theories suggest individual differences in the balance between habitual/model-free and deliberative/model-based decision-making. Methods: 127 subjects performed the two Step task and completed the blatant and subtle prejudice scale. Results: By using analyses of choices and reaction times in combination with computational modeling, subjects with stronger blatant prejudices showed a shift away from model-based control. There was no association between these decision-making processes and subtle prejudices. Conclusion: These results support the idea that blatant prejudices toward minorities are related to a relative dominance of habitual decision-making. This finding has important implications for developing interventions that target to change prejudices across societies.},
  language  = {en}
}
@article{HerbstBaalmannBykovetal.2022,
  author    = {Herbst, Konstantin and Baalmann, Lennart R. and Bykov, Andrei and Engelbrecht, N. Eugene and Ferreira, Stefan E. S. and Izmodenov, Vladislav V. and Korolkov, Sergey D. and Levenfish, Ksenia P. and Linsky, Jeffrey L. and Meyer, Dominique M. -A. and Scherer, Klaus and Strauss, R. Du Toit},
  title     = {Astrospheres of planet-hosting cool stars and beyond when modeling meets observations},
  series = {Space science reviews},
  volume    = {218},
  journal   = {Space science reviews},
  number    = {4},
  publisher = {Springer Nature},
  address   = {Dordrecht},
  issn      = {0038-6308},
  doi       = {10.1007/s11214-022-00894-3},
  pages     = {46},
  year      = {2022},
  abstract  = {Thanks to dedicated long-term missions like Voyager and GOES over the past 50 years, much insight has been gained on the activity of our Sun, the solar wind, its interaction with the interstellar medium, and, thus, about the formation, the evolution, and the structure of the heliosphere. Additionally, with the help of multi-wavelength observations by the Hubble Space Telescope, Kepler, and TESS, we not only were able to detect a variety of extrasolar planets and exomoons but also to study the characteristics of their host stars, and thus became aware that other stars drive bow shocks and astrospheres. Although features like, e.g., stellar winds, could not be measured directly, over the past years several techniques have been developed allowing us to indirectly derive properties like stellar mass-loss rates and stellar wind speeds, information that can be used as direct input to existing astrospheric modeling codes. In this review, the astrospheric modeling efforts of various stars will be presented. Starting with the heliosphere as a benchmark of astrospheric studies, investigating the paleo-heliospheric changes and the Balmer H alpha projections to 1 pc, we investigate the surroundings of cool and hot stars, but also of more exotic objects like neutron stars. While pulsar wind nebulae (PWNs) might be a source of high-energy galactic cosmic rays (GCRs), the astrospheric environments of cool and hot stars form a natural shield against GCRs. Their modulation within these astrospheres, and the possible impact of turbulence, are also addressed. This review shows that all of the presented modeling efforts are in excellent agreement with currently available observations.},
  language  = {en}
}
@article{XiongDelicZengetal.2022,
  author    = {Xiong, Yingquan and Delic, Denis and Zeng, Shufei and Chen, Xin and Chu, Chang and Hasan, Ahmed A. and Kr{\"a}mer, Bernhard K. and Klein, Thomas and Yin, Lianghong and Hocher, Berthold},
  title     = {Regulation of SARS CoV-2 host factors in the kidney and heart in rats with 5/6 nephrectomy-effects of salt, ARB, DPP4 inhibitor and SGLT2 blocker},
  series = {BMC nephrology},
  volume    = {23},
  journal   = {BMC nephrology},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {1471-2369},
  doi       = {10.1186/s12882-022-02747-1},
  pages     = {10},
  year      = {2022},
  abstract  = {Background Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstrated that RAAS-blocking agents can be safely used during a SARS-CoV-2 infection but it is unknown if DPP-4 inhibitors or SGLT2-blockers may promote COVID-19 by increasing the host viral entry enzymes ACE2 and TMPRSS2. Methods We investigated telmisartan, linagliptin and empagliflozin induced effects on renal and cardiac expression of ACE2, TMPRSS2 and key enzymes involved in RAAS (REN, AGTR2, AGT) under high-salt conditions in a non-diabetic experimental 5/6 nephrectomy (5/6 Nx) model. In the present study, the gene expression of Ace2, Tmprss2, Ren, Agtr2 and Agt was assessed with qRT-PCR and the protein expression of ACE2 and TMPRSS2 with immunohistochemistry in the following experimental groups: Sham + normal diet (ND) + placebo (PBO); 5/6Nx + ND + PBO; 5/6Nx + high salt-diet (HSD) + PBO; 5/6Nx + HSD + telmisartan; 5/6Nx + HSD + linagliptin; 5/6Nx + HSD + empagliflozin. Results In the kidney, the expression of Ace2 was not altered on mRNA level under disease and treatment conditions. The renal TMPRSS2 levels (mRNA and protein) were not affected, whereas the cardiac level was significantly increased in 5/6Nx rats. Intriguingly, the elevated TMPRSS2 protein expression in the heart was significantly normalized after treatment with telmisartan, linagliptin and empagliflozin. Conclusions Our study indicated that there is no upregulation regarding host factors potentially promoting SARS-CoV-2 virus entry into host cells when the SGLT2-blocker empagliflozin, telmisartan and the DPP4-inhibitor blocker linagliptin are used. The results obtained in a preclinical, experimental non-diabetic kidney failure model need confirmation in ongoing interventional clinical trials.},
  language  = {en}
}
@article{VoglimacciStephanopoliWendlederLantuitetal.2022,
  author    = {Voglimacci-Stephanopoli, Jo{\"e}lle and Wendleder, Anna and Lantuit, Hugues and Langlois, Alexandre and Stettner, Samuel and Schmitt, Andreas and Dedieu, Jean-Pierre and Roth, Achim and Royer, Alain},
  title     = {Potential of X-band polarimetric synthetic aperture radar co-polar phase difference for arctic snow depth estimation},
  series = {Cryosphere},
  volume    = {16},
  journal   = {Cryosphere},
  number    = {6},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-16-2163-2022},
  pages     = {2163 -- 2181},
  year      = {2022},
  abstract  = {Changes in snowpack associated with climatic warming has drastic impacts on surface energy balance in the cryosphere. Yet, traditional monitoring techniques, such as punctual measurements in the field, do not cover the full snowpack spatial and temporal variability, which hampers efforts to upscale measurements to the global scale. This variability is one of the primary constraints in model development. In terms of spatial resolution, active microwaves (synthetic aperture radar - SAR) can address the issue and outperform methods based on passive microwaves. Thus, high-spatial-resolution monitoring of snow depth (SD) would allow for better parameterization of local processes that drive the spatial variability of snow. The overall objective of this study is to evaluate the potential of the TerraSAR-X (TSX) SAR sensor and the wave co-polar phase difference (CPD) method for characterizing snow cover at high spatial resolution. Consequently, we first (1) investigate SD and depth hoar fraction (DHF) variability between different vegetation classes in the Ice Creek catchment (Qikiqtaruk/Herschel Island, Yukon, Canada) using in situ measurements collected over the course of a field campaign in 2019; (2) evaluate linkages between snow characteristics and CPD distribution over the 2019 dataset; and (3) determine CPD seasonality considering meteorological data over the 2015-2019 period. SD could be extracted using the CPD when certain conditions are met. A high incidence angle (>30 circle) with a high topographic wetness index (TWI) (>7.0) showed correlation between SD and CPD (R2 up to 0.72). Further, future work should address a threshold of sensitivity to TWI and incidence angle to map snow depth in such environments and assess the potential of using interpolation tools to fill in gaps in SD information on drier vegetation types.},
  language  = {en}
}
@article{BuchmannFielitzSpiraetal.2022,
  author    = {Buchmann, Nikolaus and Fielitz, Jens and Spira, Dominik and K{\"o}nig, Maximilian and Norman, Kristina and Pawelec, Graham and Goldeck, David and Demuth, Ilja and Steinhagen-Thiessen, Elisabeth},
  title     = {Muscle mass and inflammation in older adults: impact of the metabolic syndrome},
  series = {Gerontology},
  volume    = {68},
  journal   = {Gerontology},
  number    = {9},
  publisher = {Karger},
  address   = {Basel},
  issn      = {0304-324X},
  doi       = {10.1159/000520096},
  pages     = {989 -- 998},
  year      = {2022},
  abstract  = {Background: Inflammatory processes are a cause of accelerated loss of muscle mass. Metabolic syndrome (MetS) is a highly prevalent age-related condition, which may promote and be promoted by inflammation. However, whether inflammation in MetS (metaflammation) is associated with lower muscle mass is still unclear. Methods: Complete cross-sectional data on body composition, MetS, and the inflammatory markers interleukin (IL)-1 beta, IL-6, IL-10, tumor necrosis factor (TNF), and C-reactive protein (CRP) were available for 1,377 BASE-II participants (51.1\% women; 68 +/- 4 years old). Appendicular lean mass (ALM) was assessed by dual-energy X-ray absorptiometry. Low muscle mass (low ALM-to-BMI ratio [ALMBMI]) was defined according to the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project. Regression models, adjusted for an increasing number of confounders (sex, age, physical activity, morbidities, diabetes mellitus type II, TSH, albumin, HbA1c, smoking habits, alcohol intake, education, and energy intake/day), were used to calculate the association between low ALMBMI and high inflammation (tertile 3) according to MetS. Results: MetS was present in 36.2\% of the study population, and 9\% had low ALMBMI. In the whole study population, high CRP (odds ratio [OR]: 2.7 [95\% CI: 1.6-4.7; p = 0.001]) and high IL-6 (OR: 2.1 [95\% CI: 1.2-1.9; p = 0.005]) were associated with low ALMBMI. In contrast, no significant association was found between TNF, IL-10, or IL-1 beta with low ALMBMI. When participants were stratified by MetS, results for IL-6 remained significant only in participants with MetS. Conclusions: Among BASE-II participants, low ALMBMI was associated with inflammation. Low-grade inflammation triggered by disease state, especially in the context of MetS, might favor loss of muscle mass, so a better control of MetS might help to prevent sarcopenia. Intervention studies to test whether strategies to prevent MetS might also prevent loss of muscle mass seem to be promising.},
  language  = {en}
}
@article{GalhuberMichenthalerHeiningeretal.2022,
  author    = {Galhuber, Markus and Michenthaler, Helene and Heininger, Christoph and Reinisch, Isabel and N{\"o}ssing, Christoph and Krstic, Jelena and Kupper, Nadja and Moyschewitz, Elisabeth and Auer, Martina and Heitzer, Ellen and Ulz, Peter and Birner-Gruenberger, Ruth and Liesinger, Laura and Lenihan-Geels, Georgia Ngawai and Oster, Moritz and Spreitzer, Emil and Chiozzi, Riccardo Zenezini and Schulz, Tim J. and Schupp, Michael and Madl, Tobias and Heck, Albert J. R. and Prokesch, Andreas},
  title     = {Complementary omics strategies to dissect p53 signaling networks under nutrient stress},
  series = {Cellular and molecular life sciences},
  volume    = {79},
  journal   = {Cellular and molecular life sciences},
  number    = {6},
  publisher = {Springer Nature},
  address   = {Basel},
  issn      = {1420-682X},
  doi       = {10.1007/s00018-022-04345-8},
  pages     = {22},
  year      = {2022},
  abstract  = {Signaling trough p53is a major cellular stress response mechanism and increases upon nutrient stresses such as starvation. Here, we show in a human hepatoma cell line that starvation leads to robust nuclear p53 stabilization. Using BioID, we determine the cytoplasmic p53 interaction network within the immediate-early starvation response and show that p53 is dissociated from several metabolic enzymes and the kinase PAK2 for which direct binding with the p53 DNA-binding domain was confirmed with NMR studies. Furthermore, proteomics after p53 immunoprecipitation (RIME) uncovered the nuclear interactome under prolonged starvation, where we confirmed the novel p53 interactors SORBS1 (insulin receptor signaling) and UGP2 (glycogen synthesis). Finally, transcriptomics after p53 re-expression revealed a distinct starvation-specific transcriptome response and suggested previously unknown nutrient-dependent p53 target genes. Together, our complementary approaches delineate several nodes of the p53 signaling cascade upon starvation, shedding new light on the mechanisms of p53 as nutrient stress sensor. Given the central role of p53 in cancer biology and the beneficial effects of fasting in cancer treatment, the identified interaction partners and networks could pinpoint novel pharmacologic targets to fine-tune p53 activity.},
  language  = {en}
}
@article{OranWeissSantacruzPichetal.2022,
  author    = {Oran, Rona and Weiss, Benjamin P. and Santacruz-Pich, Maria De Soria and Jun, Insoo and Lawrence, David J. and Polanskey, Carol A. and Ratliff, J. Martin and Raymond, Carol A. and Ream, Jodie B. and Russell, Christopher T. and Shprits, Yuri Y. and Zuber, Maria T. and Elkins-Tanton, Linda T.},
  title     = {Maximum energies of trapped particles around magnetized planets and small bodies},
  series = {Geophysical research letters},
  volume    = {49},
  journal   = {Geophysical research letters},
  number    = {13},
  publisher = {American Geophysical Union},
  address   = {Washington},
  issn      = {0094-8276},
  doi       = {10.1029/2021GL097014},
  pages     = {11},
  year      = {2022},
  abstract  = {Energetic charged particles trapped in planetary radiation belts are hazardous to spacecraft. Planned missions to iron-rich asteroids with possible strong remanent magnetic fields require an assessment of trapped particles energies. Using laboratory measurements of iron meteorites, we estimate the largest possible asteroid magnetic moment. Although weak compared to moments of planetary dynamos, the small body size may yield strong surface fields. We use hybrid simulations to confirm the formation of a magnetosphere with an extended quasi-dipolar region. However, the short length scale of the field implies that energetic particle motion would be nonadiabatic, making existing radiation belt theories not applicable. Our idealized particle simulations demonstrate that chaotic motions lead to particle loss at lower energies than those predicted by adiabatic theory, which may explain the energies of transiently trapped particles observed at Mercury, Ganymede, and Earth. However, even the most magnetized asteroids are unlikely to stably trap hazardous particles.},
  language  = {en}
}
@article{DhahbiChaabeneChaouachietal.2022,
  author    = {Dhahbi, Wissem and Chaabene, Helmi and Chaouachi, Anis and Padulo, Johnny and Behm, David G. and Cochrane, Jodie and Burnett, Angus and Chamari, Karim},
  title     = {Kinetic analysis of push-up exercises: a systematic review with practical recommendations},
  series = {Sports biomechanics},
  volume    = {21},
  journal   = {Sports biomechanics},
  number    = {1},
  publisher = {Routledge},
  address   = {Abingdon},
  issn      = {1476-3141},
  doi       = {10.1080/14763141.2018.1512149},
  pages     = {1 -- 40},
  year      = {2022},
  abstract  = {Push-ups represent one of the simplest and most popular strengthening exercise. The aim of this study was to systematically review and critically appraise the literature on the kinetics-related characteristics of different types of push-ups, with the objective of optimising training prescription and exercise-related load. A systematic search was conducted in the electronic databases PubMed, Google Scholar and Science Direct up to April 2018. Studies that reported kinetic data (e.g. initial and peak-force supported by the upper-limbs, impact-force, peak-flexion-moment of the elbow-joint, rate of propulsive- and impact-, and vertebral-joint compressive-forces) related to push-ups and included trained, recreational and untrained participants, were considered. The risk of bias in the included studies was assessed using the Critical Appraisal Skills Programme scale. From 5290 articles retrieved in the initial search, only 26 studies were included in this review. Kinetic data for 46 push-up variants were assessed. A limitation of the current review is that the relationship between our findings and actual clinical or practical consequences is not statistically proven but can only be inferred from our critical descriptive approach. Overall, this review provides detailed data on specific characteristics and intensities of push-up variations, in order to optimise exercise prescription for training and rehabilitation purposes.},
  language  = {en}
}
@article{HerrmannBodenMaureretal.2022,
  author    = {Herrmann, Matthias L. and Boden, Cindy and Maurer, Christoph and Kentischer, Felix and Mennig, Eva and Wagner, S{\"o}ren and Conzelmann, Lars O. and F{\"o}rstner, Bernd R. and Rapp, Michael A. and von Arnim, Christine A. F. and Denkinger, Michael and Eschweiler, Gerhard W. and Thomas, Christine},
  title     = {Anticholinergic drug exposure increases the risk of delirium in older patients undergoing elective surgery},
  series = {Frontiers in medicine},
  volume    = {9},
  journal   = {Frontiers in medicine},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-858X},
  doi       = {10.3389/fmed.2022.871229},
  pages     = {8},
  year      = {2022},
  abstract  = {IntroductionPostoperative delirium (POD) is a common and serious adverse event of surgery in older people. Because of its great impact on patients' safety and quality of life, identification of modifiable risk factors could be useful. Although preoperative medication intake is assumed to be an important modifiable risk factor, the impact of anticholinergic drugs on the occurrence of POD seems underestimated in elective surgery. The aim of this study was to investigate the association between preoperative anticholinergic burden and POD. We hypothesized that a high preoperative anticholinergic burden is an independent, potentially modifiable predisposing and precipitating factor of POD in older people. MethodsBetween November 2017 and April 2019, 1,470 patients of 70 years and older undergoing elective orthopedic, general, cardiac, or vascular surgery were recruited in the randomized, prospective, multicenter PAWEL trial. Anticholinergic burden of a sub-cohort of 899 patients, who did not receive a multimodal intervention for preventing POD, was assessed by two different tools at hospital admission: The established Anticholinergic Risk Scale (ARS) and the recently developed Anticholinergic Burden Score (ABS). POD was detected by confusion assessment method (CAM) and a validated post discharge medical record review. Logistic regression analyses were performed to evaluate the association between anticholinergic burden and POD. ResultsPOD was observed in 210 of 899 patients (23.4\%). Both ARS and ABS were independently associated with POD. The association persisted after adjustment for relevant confounding factors such as age, sex, comorbidities, preoperative cognitive and physical status, number of prescribed drugs, surgery time, type of surgery and anesthesia, usage of heart-lung-machine, and treatment in intensive care unit. If a patient was taking one of the 56 drugs listed in the ABS, risk for POD was 2.7-fold higher (OR = 2.74, 95\% CI = 1.55-4.94) and 1.5-fold higher per additional point on the ARS (OR = 1.54, 95\% CI = 1.15-2.02). ConclusionPreoperative anticholinergic drug exposure measured by ARS or ABS was independently associated with POD in older patients undergoing elective surgery. Therefore, identification, discontinuation or substitution of anticholinergic medication prior to surgery may be a promising approach to reduce the risk of POD in older patients.},
  language  = {en}
}
@article{HaugkJongejansMangelsdorfetal.2022,
  author    = {Haugk, Charlotte and Jongejans, Loeka L. and Mangelsdorf, Kai and Fuchs, Matthias and Ogneva, Olga and Palmtag, Juri and Mollenhauer, Gesine and Mann, Paul J. and Overduin, P. Paul and Grosse, Guido and Sanders, Tina and Tuerena, Robyn E. and Schirrmeister, Lutz and Wetterich, Sebastian and Kizyakov, Alexander and Karger, Cornelia and Strauss, Jens},
  title     = {Organic matter characteristics of a rapidly eroding permafrost cliff in NE Siberia (Lena Delta, Laptev Sea region)},
  series = {Biogeosciences},
  volume    = {19},
  journal   = {Biogeosciences},
  number    = {7},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1726-4170},
  doi       = {10.5194/bg-19-2079-2022},
  pages     = {2079 -- 2094},
  year      = {2022},
  abstract  = {Organic carbon (OC) stored in Arctic permafrost represents one of Earth's largest and most vulnerable terrestrial carbon pools. Amplified climate warming across the Arctic results in widespread permafrost thaw. Permafrost deposits exposed at river cliffs and coasts are particularly susceptible to thawing processes. Accelerating erosion of terrestrial permafrost along shorelines leads to increased transfer of organic matter (OM) to nearshore waters. However, the amount of terrestrial permafrost carbon and nitrogen as well as the OM quality in these deposits is still poorly quantified. We define the OM quality as the intrinsic potential for further transformation, decomposition and mineralisation. Here, we characterise the sources and the quality of OM supplied to the Lena River at a rapidly eroding permafrost river shoreline cliff in the eastern part of the delta (Sobo-Sise Island). Our multi-proxy approach captures bulk elemental, molecu- lar geochemical and carbon isotopic analyses of Late Pleistocene Yedoma permafrost and Holocene cover deposits, discontinuously spanning the last similar to 52 kyr. We showed that the ancient permafrost exposed in the Sobo-Sise cliff has a high organic carbon content (mean of about 5 wt \%). The oldest sediments stem from Marine Isotope Stage (MIS) 3 interstadial deposits (dated to 52 to 28 cal ka BP) and are overlaid by last glacial MIS 2 (dated to 28 to 15 cal ka BP) and Holocene MIS 1 (dated to 7-0 cal ka BP) deposits. The relatively high average chain length (ACL) index of n-alkanes along the cliff profile indicates a predominant contribution of vascular plants to the OM composition. The elevated ratio of isoand anteiso-branched fatty acids (FAs) relative to mid- and long-chain (C >= 20) n-FAs in the interstadial MIS 3 and the interglacial MIS 1 deposits suggests stronger microbial activity and consequently higher input of bacterial biomass during these climatically warmer periods. The overall high carbon preference index (CPI) and higher plant fatty acid (HPFA) values as well as high C/N ratios point to a good quality of the preserved OM and thus to a high potential of the OM for decomposition upon thaw. A decrease in HPFA values downwards along the profile probably indicates stronger OM decomposition in the oldest (MIS 3) deposits of the cliff. The characterisation of OM from eroding permafrost leads to a better assessment of the greenhouse gas potential of the OC released into river and nearshore waters in the future.},
  language  = {en}
}
@article{JaraMunozMelnickLietal.2022,
  author    = {Jara-Mu{\~n}oz, Julius and Melnick, Daniel and Li, Shaoyang and Socquet, Anne and Cort{\´e}s-Aranda, Joaqu{\´i}n and Brill, Dominik and Strecker, Manfred R.},
  title     = {The cryptic seismic potential of the Pichilemu blind fault in Chile revealed by off-fault geomorphology},
  series = {Nature communications},
  volume    = {13},
  journal   = {Nature communications},
  number    = {1},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-022-30754-1},
  pages     = {13},
  year      = {2022},
  abstract  = {The first step towards assessing hazards in seismically active regions involves mapping capable faults and estimating their recurrence times. While the mapping of active faults is commonly based on distinct geologic and geomorphic features evident at the surface, mapping blind seismogenic faults is complicated by the absence of on-fault diagnostic features. Here we investigated the Pichilemu Fault in coastal Chile, unknown until it generated a Mw 7.0 earthquake in 2010. The lack of evident surface faulting suggests activity along a partly-hidden blind fault. We used off-fault deformed marine terraces to estimate a fault-slip rate of 0.52 +/- 0.04 m/ka, which, when integrated with satellite geodesy suggests a 2.12 +/- 0.2 ka recurrence time for Mw similar to 7.0 normal-faulting earthquakes. We propose that extension in the Pichilemu region is associated with stress changes during megathrust earthquakes and accommodated by sporadic slip during upper-plate earthquakes, which has implications for assessing the seismic potential of cryptic faults along convergent margins and elsewhere.},
  language  = {en}
}
@article{AguileraDenaLangerAntoniadisetal.2022,
  author    = {Aguilera-Dena, David R. and Langer, Norbert and Antoniadis, John and Pauli, Daniel and Dessart, Luc and Vigna-G{\´o}mez, Alejandro and Gr{\"a}fener, G{\"o}tz and Yoon, Sung-Chul},
  title     = {Stripped-envelope stars in different metallicity environments: I. Evolutionary phases, classification, and populations},
  series = {Astronomy and astrophysics},
  volume    = {661},
  journal   = {Astronomy and astrophysics},
  publisher = {EDP Sciences},
  address   = {Les Ulis},
  issn      = {0004-6361},
  doi       = {10.1051/0004-6361/202142895},
  pages     = {20},
  year      = {2022},
  abstract  = {Massive stars that become stripped of their hydrogen envelope through binary interaction or winds can be observed either as Wolf-Rayet stars, if they have optically thick winds, or as transparent-wind stripped-envelope stars. We approximate their evolution through evolutionary models of single helium stars, and compute detailed model grids in the initial mass range 1.5-70 M. for metallicities between 0.01 and 0.04, from core helium ignition until core collapse. Throughout their lifetimes some stellar models expose the ash of helium burning. We propose that models that have nitrogen-rich envelopes are candidate WN stars, while models with a carbon-rich surface are candidate WC stars during core helium burning, and WO stars afterwards. We measure the metallicity dependence of the total lifetimes of our models and the duration of their evolutionary phases. We propose an analytic estimate of the wind's optical depth to distinguish models of Wolf-Rayet stars from transparent-wind stripped-envelope stars, and find that the luminosity ranges at which WN-, WC-, and WO-type stars can exist is a strong function of metallicity. We find that all carbon-rich models produced in our grids have optically thick winds and match the luminosity distribution of observed populations. We construct population models and predict the numbers of transparent-wind stripped-envelope stars and Wolf-Rayet stars, and derive their number ratios at different metallicities. We find that as metallicity increases, the number of transparent-wind stripped-envelope stars decreases and the number of Wolf-Rayet stars increases. At high metallicities WC- and WO-type stars become more common. We apply our population models to nearby galaxies, and find that populations are more sensitive to the transition luminosity between Wolf-Rayet stars and transparent-wind helium stars than to the metallicity-dependent mass loss rates.},
  language  = {en}
}
@article{HeistermannBogenaFranckeetal.2022,
  author    = {Heistermann, Maik and Bogena, Heye and Francke, Till and G{\"u}ntner, Andreas and Jakobi, Jannis and Rasche, Daniel and Schr{\"o}n, Martin and D{\"o}pper, Veronika and Fersch, Benjamin and Groh, Jannis and Patil, Amol and P{\"u}tz, Thomas and Reich, Marvin and Zacharias, Steffen and Zengerle, Carmen and Oswald, Sascha},
  title     = {Soil moisture observation in a forested headwater catchment: Combining a dense cosmic-ray neutron sensor network with roving and hydrogravimetry at the TERENO site W{\"u}stebach},
  series = {Earth system science data},
  volume    = {14},
  journal   = {Earth system science data},
  number    = {5},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1866-3508},
  doi       = {10.5194/essd-14-2501-2022},
  pages     = {2501 -- 2519},
  year      = {2022},
  abstract  = {Cosmic-ray neutron sensing (CRNS) has become an effective method to measure soil moisture at a horizontal scale of hundreds of metres and a depth of decimetres. Recent studies proposed operating CRNS in a network with overlapping footprints in order to cover root-zone water dynamics at the small catchment scale and, at the same time, to represent spatial heterogeneity. In a joint field campaign from September to November 2020 (JFC-2020), five German research institutions deployed 15 CRNS sensors in the 0.4 km(2) Wustebach catchment (Eifel mountains, Germany). The catchment is dominantly forested (but includes a substantial fraction of open vegetation) and features a topographically distinct catchment boundary. In addition to the dense CRNS coverage, the campaign featured a unique combination of additional instruments and techniques: hydro-gravimetry (to detect water storage dynamics also below the root zone); ground-based and, for the first time, airborne CRNS roving; an extensive wireless soil sensor network, supplemented by manual measurements; and six weighable lysimeters. Together with comprehensive data from the long-term local research infrastructure, the published data set (available at https://doi.org/10.23728/b2share.756ca0485800474e9dc7f5949c63b872; Heistermann et al., 2022) will be a valuable asset in various research contexts: to advance the retrieval of landscape water storage from CRNS, wireless soil sensor networks, or hydrogravimetry; to identify scale-specific combinations of sensors and methods to represent soil moisture variability; to improve the understanding and simulation of land-atmosphere exchange as well as hydrological and hydrogeological processes at the hillslope and the catchment scale; and to support the retrieval of soil water content from airborne and spaceborne remote sensing platforms.},
  language  = {en}
}
@article{FuchsPalmtagJuhlsetal.2022,
  author    = {Fuchs, Matthias and Palmtag, Juri and Juhls, Bennet and Overduin, Pier Paul and Grosse, Guido and Abdelwahab, Ahmed and Bedington, Michael and Sanders, Tina and Ogneva, Olga and Fedorova, Irina and Zimov, Nikita S. and Mann, Paul J. and Strauss, Jens},
  title     = {High-resolution bathymetry models for the Lena Delta and Kolyma Gulf coastal zones},
  series = {Earth system science data},
  volume    = {14},
  journal   = {Earth system science data},
  number    = {5},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1866-3508},
  doi       = {10.5194/essd-14-2279-2022},
  pages     = {2279 -- 2301},
  year      = {2022},
  abstract  = {Arctic river deltas and deltaic near-shore zones represent important land-ocean transition zones influencing sediment dynamics and nutrient fluxes from permafrost-affected terrestrial ecosystems into the coastal Arctic Ocean. To accurately model fluvial carbon and freshwater export from rapidly changing river catchments as well as assess impacts of future change on the Arctic shelf and coastal ecosystems, we need to understand the sea floor characteristics and topographic variety of the coastal zones. To date, digital bathymetrical data from the poorly accessible, shallow, and large areas of the eastern Siberian Arctic shelves are sparse. We have digitized bathymetrical information for nearly 75 000 locations from large-scale (1 V 25000-1 V 500000) current and historical nautical maps of the Lena Delta and the Kolyma Gulf region in northeastern Siberia. We present the first detailed and seamless digital models of coastal zone bathymetry for both delta and gulf regions in 50 and 200m spatial resolution. We validated the resulting bathymetry layers using a combination of our own water depth measurements and a collection of available depth measurements, which showed a strong correlation (r>0.9). Our bathymetrical models will serve as an input for a high-resolution coupled hydrodynamic-ecosystem model to better quantify fluvial and coastal carbon fluxes to the Arctic Ocean, but they may be useful for a range of other studies related to Arctic delta and near-shore dynamics such as modeling of submarine permafrost, near-shore sea ice, or shelf sediment transport. The new digital high-resolution bathymetry products are available on the PANGAEA data set repository for the Lena Delta (https://doi.org/10.1594/PANGAEA.934045; Fuchs et al., 2021a) and Kolyma Gulf region (https://doi.org/10.1594/PANGAEA.934049; Fuchs et al., 2021b), respectively. Likewise, the depth validation data are available on PANGAEA as well (https://doi.org/10.1594/PANGAEA.933187; Fuchs et al., 2021c).},
  language  = {en}
}
@article{JonesGrosseFarquharsonetal.2022,
  author    = {Jones, Benjamin M. and Grosse, Guido and Farquharson, Louise M. and Roy-L{\´e}veill{\´e}e, Pascale and Veremeeva, Alexandra and Kanevskiy, Mikhail Z. and Gaglioti, Benjamin and Breen, Amy L. and Parsekian, Andrew D. and Ulrich, Mathias and Hinkel, Kenneth M.},
  title     = {Lake and drained lake basin systems in lowland permafrost regions},
  series = {Nature reviews earth and environment},
  volume    = {3},
  journal   = {Nature reviews earth and environment},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2662-138X},
  doi       = {10.1038/s43017-021-00238-9},
  pages     = {85 -- 98},
  year      = {2022},
  abstract  = {The formation, growth and drainage of lakes in Arctic and boreal lowland permafrost regions influence landscape and ecosystem processes. These lake and drained lake basin (L-DLB) systems occupy >20\% of the circumpolar Northern Hemisphere permafrost region and similar to 50\% of the area below 300 m above sea level. Climate change is causing drastic impacts to L-DLB systems, with implications for permafrost dynamics, ecosystem functioning, biogeochemical processes and human livelihoods in lowland permafrost regions. In this Review, we discuss how an increase in the number of lakes as a result of permafrost thaw and an intensifying hydrologic regime are not currently offsetting the land area gained through lake drainage, enhancing the dominance of drained lake basins (DLBs).The contemporary transition from lakes to DLBs decreases hydrologic storage, leads to permafrost aggradation, increases carbon sequestration and diversifies the shifting habitat mosaic in Arctic and boreal regions. However, further warming could inhibit permafrost aggradation in DLBs, disrupting the trajectory of important microtopographic controls on carbon fluxes and ecosystem processes in permafrost-region L-DLB systems. Further research is needed to understand the future dynamics of L-DLB systems to improve Earth system models, permafrost carbon feedback assessments, permafrost hydrology linkages, infrastructure development in permafrost regions and the well-being of northern socio-ecological systems.},
  language  = {en}
}
@article{DerežaninBlažytėDobryninetal.2022,
  author    = {Derežanin, Lorena and Blažytė, Asta and Dobrynin, Pavel and Duch{\^e}ne, David A. and Grau, Jos{\´e} Horacio and Jeon, Sungwon and Kliver, Sergei and Koepfli, Klaus-Peter and Meneghini, Dorina and Preick, Michaela and Tomarovsky, Andrey and Totikov, Azamat and Fickel, J{\"o}rns and F{\"o}rster, Daniel W.},
  title     = {Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae},
  series = {Molecular ecology},
  volume    = {31},
  journal   = {Molecular ecology},
  number    = {10},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {0962-1083},
  doi       = {10.1111/mec.16443},
  pages     = {2898 -- 2919},
  year      = {2022},
  abstract  = {Species of the mustelid subfamily Guloninae inhabit diverse habitats on multiple continents, and occupy a variety of ecological niches. They differ in feeding ecologies, reproductive strategies and morphological adaptations. To identify candidate loci associated with adaptations to their respective environments, we generated a de novo assembly of the tayra (Eira barbara), the earliest diverging species in the subfamily, and compared this with the genomes available for the wolverine (Gulo gulo) and the sable (Martes zibellina). Our comparative genomic analyses included searching for signs of positive selection, examining changes in gene family sizes and searching for species-specific structural variants. Among candidate loci associated with phenotypic traits, we observed many related to diet, body condition and reproduction. For example, for the tayra, which has an atypical gulonine reproductive strategy of aseasonal breeding, we observed species-specific changes in many pregnancy-related genes. For the wolverine, a circumpolar hypercarnivore that must cope with seasonal food scarcity, we observed many changes in genes associated with diet and body condition. All types of genomic variation examined (single nucleotide polymorphisms, gene family expansions, structural variants) contributed substantially to the identification of candidate loci. This argues strongly for consideration of variation other than single nucleotide polymorphisms in comparative genomics studies aiming to identify loci of adaptive significance.},
  language  = {en}
}
@article{AbdelilahSeyfriedIruelaArispePenningeretal.2022,
  author    = {Abdelilah-Seyfried, Salim and Iruela-Arispe, M. Luisa and Penninger, Josef M. and Tournier-Lasserve, Elisabeth and Vikkula, Miikka and Cleaver, Ondine},
  title     = {Recalibrating vascular malformations and mechanotransduction by pharmacological intervention},
  series = {Journal of clinical investigation},
  volume    = {132},
  journal   = {Journal of clinical investigation},
  number    = {8},
  publisher = {American Society for Clinical Investigation},
  address   = {Ann Arbor},
  issn      = {0021-9738},
  doi       = {10.1172/JCI160227},
  pages     = {4},
  year      = {2022},
  language  = {en}
}
@article{ZhangWangKuangetal.2022,
  author    = {Zhang, Zhihao and Wang, Ting and Kuang, Jin and Herold, Fabian and Ludyga, Sebastian and Li, Jingming and Hall, Daniel L. and Taylor, Alyx and Healy, Sean and Yeung, Albert S. and Kramer, Arthur F. and Zou, Liye},
  title     = {The roles of exercise tolerance and resilience in the effect of physical activity on emotional states among college students},
  series = {International Journal of Clinical and Health Psychology},
  volume    = {22},
  journal   = {International Journal of Clinical and Health Psychology},
  number    = {3},
  publisher = {Elsevier},
  address   = {New York},
  issn      = {1697-2600},
  doi       = {10.1016/j.ijchp.2022.100312},
  pages     = {8},
  year      = {2022},
  abstract  = {Background/objective: Negative emotional states, such as depression, anxiety, and stress challenge health care due to their long-term consequences for mental disorders. Accumulating evidence indicates that regular physical activity (PA) can positively influence negative emotional states. Among possible candidates, resilience and exercise tolerance in particular have the potential to partly explain the positive effects of PA on negative emotional states. Thus, the aim of this study was to investigate the association between PA and negative emotional states, and further determine the mediating effects of exercise tolerance and resilience in such a relationship. Method: In total, 1117 Chinese college students (50.4\% female, Mage=18.90, SD=1.25) completed a psychosocial battery, including the 21-item Depression Anxiety Stress Scale (DASS-21), the Connor-Davidson Resilience Scale (CD-RISC), the Preference for and Tolerance of the Intensity of Exercise Questionnaire (PRETIE-Q), and the International Physical Activity Questionnaire short form (IPAQ-SF). Regression analysis was used to identify the serial multiple mediation, controlling for gender, age and BMI. Results: PA, exercise intensity-tolerance, and resilience were significantly negatively correlated with negative emotional states (Ps<.05). Further, exercise tolerance and resilience partially mediated the relationship between PA and negative emotional states. Conclusions: Resilience and exercise intensity-tolerance can be achieved through regularly engaging in PA, and these newly observed variables play critical roles in prevention of mental illnesses, especially college students who face various challenges. Recommended amount of PA should be incorporated into curriculum or sport clubs within a campus environment.},
  language  = {en}
}
@article{RingEisenmannKandiletal.2022,
  author    = {Ring, Raphaela M. and Eisenmann, Clemens and Kandil, Farid and Steckhan, Nico and Demmrich, Sarah and Klatte, Caroline and Kessler, Christian S. and Jeitler, Michael and Boschmann, Michael and Michalsen, Andreas and Blakeslee, Sarah B. and St{\"o}ckigt, Barbara and Stritter, Wiebke and Koppold-Liebscher, Daniela A.},
  title     = {Mental and behavioural responses to Bah{\´a}'{\´i} fasting: Looking behind the scenes of a religiously motivated intermittent fast using a mixed methods approach},
  series = {Nutrients},
  volume    = {14},
  journal   = {Nutrients},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-6643},
  doi       = {10.3390/nu14051038},
  pages     = {23},
  year      = {2022},
  abstract  = {Background/Objective: Historically, fasting has been practiced not only for medical but also for religious reasons. Baha'is follow an annual religious intermittent dry fast of 19 days. We inquired into motivation behind and subjective health impacts of Baha'i fasting. Methods: A convergent parallel mixed methods design was embedded in a clinical single arm observational study. Semi-structured individual interviews were conducted before (n = 7), during (n = 8), and after fasting (n = 8). Three months after the fasting period, two focus group interviews were conducted (n = 5/n = 3). A total of 146 Baha'i volunteers answered an online survey at five time points before, during, and after fasting. Results: Fasting was found to play a central role for the religiosity of interviewees, implying changes in daily structures, spending time alone, engaging in religious practices, and experiencing social belonging. Results show an increase in mindfulness and well-being, which were accompanied by behavioural changes and experiences of self-efficacy and inner freedom. Survey scores point to an increase in mindfulness and well-being during fasting, while stress, anxiety, and fatigue decreased. Mindfulness remained elevated even three months after the fast. Conclusion: Baha'i fasting seems to enhance participants' mindfulness and well-being, lowering stress levels and reducing fatigue. Some of these effects lasted more than three months after fasting.},
  language  = {en}
}
@article{CaoTianHerzschuhetal.2022,
  author    = {Cao, Xianyong and Tian, Fang and Herzschuh, Ulrike and Ni, Jian and Xu, Qinghai and Li, Wenjia and Zhang, Yanrong and Luo, Mingyu and Chen, Fahu},
  title     = {Human activities have reduced plant diversity in eastern China over the last two millennia},
  series = {Global change biology},
  volume    = {28},
  journal   = {Global change biology},
  number    = {16},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1354-1013},
  doi       = {10.1111/gcb.16274},
  pages     = {4962 -- 4976},
  year      = {2022},
  abstract  = {Understanding the history and regional singularities of human impact on vegetation is key to developing strategies for sustainable ecosystem management. In this study, fossil and modern pollen datasets from China are employed to investigate temporal changes in pollen composition, analogue quality, and pollen diversity during the Holocene. Anthropogenic disturbance and vegetation's responses are also assessed. Results reveal that pollen assemblages from non-forest communities fail to provide evidence of human impact for the western part of China (annual precipitation less than 400 mm and/or elevation more than 3000 m.a.s.l.), as inferred from the stable quality of modern analogues, principal components, and diversity of species and communities throughout the Holocene. For the eastern part of China, the proportion of fossil pollen spectra with good modern analogues increases from ca. 50\% to ca. 80\% during the last 2 millennia, indicating an enhanced intensity of anthropogenic disturbance on vegetation. This disturbance has caused the pollen spectra to become taxonomically less diverse over space (reduced abundances of arboreal taxa and increased abundances of herbaceous taxa), highlighting a reduced south-north differentiation and divergence from past vegetation between regions in the eastern part of China. We recommend that care is taken in eastern China when basing the development of ecosystem management strategies on vegetation changes in the region during the last 2000 years, since humans have significantly disturbed the vegetation during this period.},
  language  = {en}
}
@article{SarrDonnadieuBoltonetal.2022,
  author    = {Sarr, Anta-Clarisse and Donnadieu, Yannick and Bolton, Clara T. and Ladant, Jean-Baptiste and Licht, Alexis and Fluteau, Fr{\´e}d{\´e}ric and Laugi{\´e}, Marie and Tardif-Becquet, Delphine and Dupont-Nivet, Guillaume},
  title     = {Neogene South Asian monsoon rainfall and wind histories diverged due to topographic effects},
  series = {Nature geoscience},
  volume    = {15},
  journal   = {Nature geoscience},
  number    = {4},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {1752-0894},
  doi       = {10.1038/s41561-022-00919-0},
  pages     = {314 -- 319},
  year      = {2022},
  abstract  = {The drivers of the evolution of the South Asian Monsoon remain widely debated. An intensification of monsoonal rainfall recorded in terrestrial and marine sediment archives from the earliest Miocene (23-20 million years ago (Ma)) is generally attributed to Himalayan uplift. However, Indian Ocean palaeorecords place the onset of a strong monsoon around 13 Ma, linked to strengthening of the southwesterly winds of the Somali Jet that also force Arabian Sea upwelling. Here we reconcile these divergent records using Earth system model simulations to evaluate the interactions between palaeogeography and ocean-atmosphere dynamics. We show that factors forcing the South Asian Monsoon circulation versus rainfall are decoupled and diachronous. Himalayan and Tibetan Plateau topography predominantly controlled early Miocene rainfall patterns, with limited impact on ocean-atmosphere circulation. The uplift of the East African and Middle Eastern topography played a pivotal role in the establishment of the modern Somali Jet structure above the western Indian Ocean, while strong upwelling initiated as a direct consequence of the emergence of the Arabian Peninsula and the onset of modern-like atmospheric circulation. Our results emphasize that although elevated rainfall seasonality was probably a persistent feature since the India-Asia collision in the Paleogene, modern-like monsoonal atmospheric circulation only emerged in the late Neogene.},
  language  = {en}
}
@article{BarcenaAslamPozdniakovaetal.2022,
  author    = {Barcena, Maria Luisa and Aslam, Muhammad and Pozdniakova, Sofya and Norman, Kristina and Ladilov, Yury},
  title     = {Cardiovascular inflammaging: mechanisms and translational aspects},
  series = {Cells},
  volume    = {11},
  journal   = {Cells},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4409},
  doi       = {10.3390/cells11061010},
  pages     = {15},
  year      = {2022},
  abstract  = {Aging is one of the major non-reversible risk factors for several chronic diseases, including cancer, type 2 diabetes, dementia, and cardiovascular diseases (CVD), and it is a key cause of multimorbidity, disability, and frailty (decreased physical activity, fatigue, and weight loss). The underlying cellular mechanisms are complex and consist of multifactorial processes, such as telomere shortening, chronic low-grade inflammation, oxidative stress, mitochondrial dysfunction, accumulation of senescent cells, and reduced autophagy. In this review, we focused on the molecular mechanisms and translational aspects of cardiovascular aging-related inflammation, i.e., inflammaging.},
  language  = {en}
}
@article{GiannettiUmanskySened2022,
  author    = {Giannetti, Daniela and Umansky, Karen and Sened, Itai},
  title     = {The entry of the M5S and the reshaping of party politics in Italy (2008-2018)},
  series = {Government \& opposition},
  volume    = {59},
  journal   = {Government \& opposition},
  number    = {2},
  publisher = {Cambridge University Press},
  address   = {Cambridge},
  issn      = {0017-257X},
  doi       = {10.1017/gov.2022.38},
  pages     = {464 -- 481},
  year      = {2022},
  abstract  = {This article examines how challenger parties enter the political arena and the effect of this entry by looking at the Italian 5 Star Movement (Movimento 5 Stelle - M5S). We explain the M5S's entry strategy in 2013 using the spatial approach to party competition and employing expert survey data collected for each national election between 2008 and 2018. These data allow us to analyse the changing spatial configuration of Italian politics due to the increasing salience of pro/anti-EU and pro/anti-immigration dimensions. We then apply the theoretical notion of the uncovered set (UCS) to trace how the M5S's entry reshaped the overall space of party competition, causing a realignment of existing parties. This work contributes to the ongoing debate on the electoral success of challenger parties and the emerging cleavages and polarization of party systems in Western European countries.},
  language  = {en}
}
@article{MarinBeloquiZhangGuoetal.2022,
  author    = {Marin-Beloqui, Jose and Zhang, Guanran and Guo, Junjun and Shaikh, Jordan and Wohrer, Thibaut and Hosseini, Seyed Mehrdad and Sun, Bowen and Shipp, James and Auty, Alexander J. and Chekulaev, Dimitri and Ye, Jun and Chin, Yi-Chun and Sullivan, Michael B. and Mozer, Attila J. and Kim, Ji-Seon and Shoaee, Safa and Clarke, Tracey M.},
  title     = {Insight into the origin of trapping in polymer/fullerene blends with a systematic alteration of the fullerene to higher adducts},
  series = {Journal of physical chemistry C},
  volume    = {126},
  journal   = {Journal of physical chemistry C},
  number    = {5},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {1932-7447},
  doi       = {10.1021/acs.jpcc.1c10378},
  pages     = {2708 -- 2719},
  year      = {2022},
  abstract  = {The bimolecular recombination characteristics of conjugated polymer poly[(4,4'-bis(2-ethylhexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(2,5-bis 3-tetradecylthiophen-2-y1 thiazolo 5,4-d thiazole)-2,5diy1] (PDTSiTTz) blended with the fullerene series PC60BM, ICMA, ICBA, and ICTA have been investigated using microsecond and femtosecond transient absorption spectroscopy, in conjunction with electroluminescence measurements and ambient photoemission spectroscopy. The non-Langevin polymer PDTSiTTz allows an inspection of intrinsic bimolecular recombination rates uninhibited by diffusion, while the low oscillator strengths of fullerenes allow polymer features to dominate, and we compare our results to those of the well-known polymer Si-PCPDTBT. Using mu s-TAS, we have shown that the trap -limited decay dynamics of the PDTSiTTz polaron becomes progressively slower across the fullerene series, while those of Si-PCPDTBT are invariant. Electroluminescence measurements showed an unusual double peak in pristine PDTSiTTz, attributed to a low energy intragap charge transfer state, likely interchain in nature. Furthermore, while the pristine PDTSiTTz showed a broad, low-intensity density of states, the ICBA and ICTA blends presented a virtually identical DOS to Si-PCPDTBT and its blends. This has been attributed to a shift from a delocalized, interchain highest occupied molecular orbital (HOMO) in the pristine material to a dithienosilole-centered HOMO in the blends, likely a result of the bulky fullerenes increasing interchain separation. This HOMO localization had a side effect of progressively shifting the polymer HOMO to shallower energies, which was correlated with the observed decrease in bimolecular recombination rate and increased "trap" depth. However, since the density of tail states remained the same, this suggests that the traditional viewpoint of "trapping" being dominated by tail states may not encompass the full picture and that the breadth of the DOS may also have a strong influence on bimolecular recombination.},
  language  = {en}
}
@article{FlovenzWangHersiretal.2022,
  author    = {Fl{\´o}venz, {\´O}lafur G. and Wang, Rongjiang and Hersir, Gylfi P{\´a}ll and Dahm, Torsten and Hainzl, Sebastian and Vassileva, Magdalena and Drouin, Vincent and Heimann, Sebastian and Isken, Marius Paul and Gudnason, Egill {\´A}. and {\´A}g{\´u}stsson, Kristj{\´a}n and {\´A}g{\´u}stsd{\´o}ttir, Thorbj{\"o}rg and Hor{\´a}lek, Josef and Motagh, Mahdi and Walter, Thomas R. and Rivalta, Eleonora and Jousset, Philippe and Krawczyk, Charlotte M. and Milkereit, Claus},
  title     = {Cyclical geothermal unrest as a precursor to Iceland's 2021 Fagradalsfjall eruption},
  series = {Nature geoscience},
  volume    = {15},
  journal   = {Nature geoscience},
  number    = {5},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {1752-0894},
  doi       = {10.1038/s41561-022-00930-5},
  pages     = {397 -- 404},
  year      = {2022},
  abstract  = {Understanding and constraining the source of geodetic deformation in volcanic areas is an important component of hazard assessment. Here, we analyse deformation and seismicity for one year before the March 2021 Fagradalsfjall eruption in Iceland. We generate a high-resolution catalogue of 39,500 earthquakes using optical cable recordings and develop a poroelastic model to describe three pre-eruptional uplift and subsidence cycles at the Svartsengi geothermal field, 8 km west of the eruption site. We find the observed deformation is best explained by cyclic intrusions into a permeable aquifer by a fluid injected at 4 km depth below the geothermal field, with a total volume of 0.11 ± 0.05 km3 and a density of 850 ± 350 kg m-3. We therefore suggest that ingression of magmatic CO2 can explain the geodetic, gravity and seismic data, although some contribution of magma cannot be excluded.},
  language  = {en}
}
@article{KayaDupontNivetFrielingetal.2022,
  author    = {Kaya, Mustafa Y{\"u}cel and Dupont-Nivet, Guillaume and Frieling, Joost and Fioroni, Chiara and Rohrmann, Alexander and Alt{\i}ner, Sevin{\c{c}} {\"O}zkan and Vardar, Ezgi and Tanyas, Hakan and Mamtimin, Mehmut and Zhaojie, Guo},
  title     = {The Eurasian epicontinental sea was an important carbon sink during the Palaeocene-Eocene thermal maximum},
  series = {Communications earth and environment},
  volume    = {3},
  journal   = {Communications earth and environment},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2662-4435},
  doi       = {10.1038/s43247-022-00451-4},
  pages     = {10},
  year      = {2022},
  abstract  = {The Palaeocene-Eocene Thermal Maximum (ca. 56 million years ago) offers a primary analogue for future global warming and carbon cycle recovery. Yet, where and how massive carbon emissions were mitigated during this climate warming event remains largely unknown. Here we show that organic carbon burial in the vast epicontinental seaways that extended over Eurasia provided a major carbon sink during the Palaeocene-Eocene Thermal Maximum. We coupled new and existing stratigraphic analyses to a detailed paleogeographic framework and using spatiotemporal interpolation calculated ca. 720-1300 Gt organic carbon excess burial, focused in the eastern parts of the Eurasian epicontinental seaways. A much larger amount (2160-3900 Gt C, and when accounting for the increase in inundated shelf area 7400-10300 Gt C) could have been sequestered in similar environments globally. With the disappearance of most epicontinental seas since the Oligocene-Miocene, an effective negative carbon cycle feedback also disappeared making the modern carbon cycle critically dependent on the slower silicate weathering feedback.},
  language  = {en}
}
@article{CescaSuganRudzinskietal.2022,
  author    = {Cesca, Simone and Sugan, Monica and Rudzinski, Lukasz and Vajedian, Sanaz and Niemz, Peter and Plank, Simon and Petersen, Gesa and Deng, Zhiguo and Rivalta, Eleonora and Vuan, Alessandro and Linares, Milton Percy Plasencia and Heimann, Sebastian and Dahm, Torsten},
  title     = {Massive earthquake swarm driven by magmatic intrusion at the Bransfield Strait, Antarctica},
  series = {Communications earth and environment},
  volume    = {3},
  journal   = {Communications earth and environment},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2662-4435},
  doi       = {10.1038/s43247-022-00418-5},
  pages     = {11},
  year      = {2022},
  abstract  = {An earthquake swarm affected the Bransfield Strait, Antarctica, a unique rift basin in transition from intra-arc rifting to ocean spreading. The swarm, counting similar to 85,000 volcano-tectonic earthquakes since August 2020, is located close to the Orca submarine volcano, previously considered inactive. Simultaneously, geodetic data reported up to similar to 11 cm north-westward displacement over King George Island. We use a broad variety of geophysical data and methods to reveal the complex migration of seismicity, accompanying the intrusion of 0.26-0.56 km(3) of magma. Strike-slip earthquakes mark the intrusion at depth, while shallower normal faulting the similar to 20 km long lateral growth of a dike. Seismicity abruptly decreased after a Mw 6.0 earthquake, suggesting the magmatic dike lost pressure with the slipping of a large fault. A seafloor eruption is likely, but not confirmed by sea surface temperature anomalies. The unrest documents episodic magmatic intrusion in the Bransfield Strait, providing unique insights into active continental rifting.},
  language  = {en}
}
@article{BouamraZouhalRateletal.2022,
  author    = {Bouamra, Marwa and Zouhal, Hassane and Ratel, S{\´e}bastien and Makhlouf, Issam and Bezrati, Ikram and Chtara, Mokhtar and Behm, David G. and Granacher, Urs and Chaouachi, Anis},
  title     = {Concurrent training promotes greater gains on body composition and components of physical fitness than single-mode training (endurance or resistance) in youth with obesity},
  series = {Frontiers in physiology},
  volume    = {13},
  journal   = {Frontiers in physiology},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2022.869063},
  pages     = {16},
  year      = {2022},
  abstract  = {The prevalence of obesity in the pediatric population has become a major public health issue. Indeed, the dramatic increase of this epidemic causes multiple and harmful consequences, Physical activity, particularly physical exercise, remains to be the cornerstone of interventions against childhood obesity. Given the conflicting findings with reference to the relevant literature addressing the effects of exercise on adiposity and physical fitness outcomes in obese children and adolescents, the effect of duration-matched concurrent training (CT) [50\% resistance (RT) and 50\% high-intensity-interval-training (HIIT)] on body composition and physical fitness in obese youth remains to be elucidated. Thus, the purpose of this study was to examine the effects of 9-weeks of CT compared to RT or HIIT alone, on body composition and selected physical fitness components in healthy sedentary obese youth. Out of 73 participants, only 37; [14 males and 23 females; age 13.4 +/- 0.9 years; body-mass-index (BMI): 31.2 +/- 4.8 kg center dot m-2] were eligible and randomized into three groups: HIIT (n = 12): 3-4 setsx12 runs at 80-110\% peak velocity, with 10-s passive recovery between bouts; RT (n = 12): 6 exercises; 3-4 sets x 10 repetition maximum (RM) and CT (n = 13): 50\% serial completion of RT and HIIT. CT promoted significant greater gains compared to HIIT and RT on body composition (p < 0.01, d = large), 6-min-walking test distance (6 MWT-distance) and on 6 MWT-VO2max (p < 0.03, d = large). In addition, CT showed substantially greater improvements than HIIT in the medicine ball throw test (20.2 vs. 13.6\%, p < 0.04, d = large). On the other hand, RT exhibited significantly greater gains in relative hand grip strength (p < 0.03, d = large) and CMJ (p < 0.01, d = large) than HIIT and CT. CT promoted greater benefits for fat, body mass loss and cardiorespiratory fitness than HIIT or RT modalities. This study provides important information for practitioners and therapists on the application of effective exercise regimes with obese youth to induce significant and beneficial body composition changes. The applied CT program and the respective programming parameters in terms of exercise intensity and volume can be used by practitioners as an effective exercise treatment to fight the pandemic overweight and obesity in youth.},
  language  = {en}
}
@article{RosinLaiMouldetal.2022,
  author    = {Rosin, Paul L. and Lai, Yu-Kun and Mould, David and Yi, Ran and Berger, Itamar and Doyle, Lars and Lee, Seungyong and Li, Chuan and Liu, Yong-Jin and Semmo, Amir and Shamir, Ariel and Son, Minjung and Winnem{\"o}ller, Holger},
  title     = {NPRportrait 1.0: A three-level benchmark for non-photorealistic rendering of portraits},
  series = {Computational visual media},
  volume    = {8},
  journal   = {Computational visual media},
  number    = {3},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2096-0433},
  doi       = {10.1007/s41095-021-0255-3},
  pages     = {445 -- 465},
  year      = {2022},
  abstract  = {Recently, there has been an upsurge of activity in image-based non-photorealistic rendering (NPR), and in particular portrait image stylisation, due to the advent of neural style transfer (NST). However, the state of performance evaluation in this field is poor, especially compared to the norms in the computer vision and machine learning communities. Unfortunately, the task of evaluating image stylisation is thus far not well defined, since it involves subjective, perceptual, and aesthetic aspects. To make progress towards a solution, this paper proposes a new structured, three-level, benchmark dataset for the evaluation of stylised portrait images. Rigorous criteria were used for its construction, and its consistency was validated by user studies. Moreover, a new methodology has been developed for evaluating portrait stylisation algorithms, which makes use of the different benchmark levels as well as annotations provided by user studies regarding the characteristics of the faces. We perform evaluation for a wide variety of image stylisation methods (both portrait-specific and general purpose, and also both traditional NPR approaches and NST) using the new benchmark dataset.},
  language  = {en}
}
@article{IrrgangBendixenFarquharsonetal.2022,
  author    = {Irrgang, Anna M. and Bendixen, Mette and Farquharson, Louise M. and Baranskaya, Alisa and Erikson, Li H. and Gibbs, Ann E. and Ogorodov, Stanislav A. and Overduin, Pier Paul and Lantuit, Hugues and Grigoriev, Mikhail N. and Jones, Benjamin M.},
  title     = {Drivers, dynamics and impacts of changing Arctic coasts},
  series = {Nature reviews earth and environment},
  volume    = {3},
  journal   = {Nature reviews earth and environment},
  number    = {1},
  publisher = {Nature Research},
  address   = {London},
  issn      = {2662-138X},
  doi       = {10.1038/s43017-021-00232-1},
  pages     = {39 -- 54},
  year      = {2022},
  abstract  = {Arctic coasts are vulnerable to the effects of climate change, including rising sea levels and the loss of permafrost, sea ice and glaciers. Assessing the influence of anthropogenic warming on Arctic coastal dynamics, however, is challenged by the limited availability of observational, oceanographic and environmental data. Yet, with the majority of permafrost coasts being erosive, coupled with projected intensification of erosion and flooding, understanding these changes is critical. In this Review, we describe the morphological diversity of Arctic coasts, discuss important drivers of coastal change, explain the specific sensitivity of Arctic coasts to climate change and provide an overview of pan-Arctic shoreline change and its multifaceted impacts. Arctic coastal changes impact the human environment by threatening coastal settlements, infrastructure, cultural sites and archaeological remains. Changing sediment fluxes also impact the natural environment through carbon, nutrient and pollutant release on a magnitude that remains difficult to predict. Increasing transdisciplinary and interdisciplinary collaboration efforts will build the foundation for identifying sustainable solutions and adaptation strategies to reduce future risks for those living on, working at and visiting the rapidly changing Arctic coast.},
  language  = {en}
}
@article{IzotovChisholmWorsecketal.2022,
  author    = {Izotov, Yuri I. and Chisholm, John and Worseck, G{\´a}bor and Guseva, Natalia G. and Schaerer, Daniel and Prochaska, Jason Xavier},
  title     = {Lyman alpha and Lyman continuum emission of Mg II-selected star-forming galaxies},
  series = {Monthly notices of the Royal Astronomical Society},
  volume    = {515},
  journal   = {Monthly notices of the Royal Astronomical Society},
  number    = {2},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0035-8711},
  doi       = {10.1093/mnras/stac1899},
  pages     = {2864 -- 2881},
  year      = {2022},
  abstract  = {We present observations with the Cosmic Origins Spectrograph onboard the Hubble Space Telescope of seven compact low-mass star-forming galaxies at redshifts, z, in the range 0.3161-0.4276, with various O3Mg2 = [O III] lambda 5007/Mg II lambda 2796+2803 and Mg-2 = Mg II lambda 2796/Mg II lambda 2803 emission-line ratios. We aim to study the dependence of leaking Lyman continuum (LyC) emission on the characteristics of Mg ii emission together with the dependencies on other indirect indicators of escaping ionizing radiation. LyC emission with escape fractions f(esc)(LyC) = 3.1-4.6 per cent is detected in four galaxies, whereas only 1 sigma upper limits of f(esc)(LyC) in the remaining three galaxies were derived. A strong narrow Ly alpha emission line with two peaks separated by V-sep similar to 298-592 km s(-1) was observed in four galaxies with detected LyC emission and very weak Ly alpha emission is observed in galaxies with LyC non-detections. Our new data confirm the tight anticorrelation between f(esc)(LyC) and V-sep found for previous low-redshift galaxy samples. V-sep remains the best indirect indicator of LyC leakage among all considered indicators. It is found that escaping LyC emission is detected predominantly in galaxies with Mg-2 greater than or similar to 1.3. A tendency of an increase of f(esc)(LyC) with increasing of both the O3Mg2 and Mg-2 is possibly present. However, there is substantial scatter in these relations not allowing their use for reliable prediction of f(esc)(LyC).},
  language  = {en}
}
@article{Borysek2022,
  author    = {Bor{\´y}sek, Martin},
  title     = {In search of Ovidian hebrew},
  series = {Acta Universitatis Carolinae : AUC},
  journal   = {Acta Universitatis Carolinae : AUC},
  number    = {4},
  publisher = {Karolinum Press},
  address   = {Prag},
  issn      = {0567-8269},
  doi       = {10.14712/24646830.2022.11},
  pages     = {29 -- 56},
  year      = {2022},
  abstract  = {This paper focuses on the first substantial translation of Ovid's Metamorphoses into modern Hebrew, whose author was Yehoshua Friedman (1885-1934). The first part of the paper sets Friedman into the context of modern Hebrew classical philology and explores the character of his verse. The core of the text consists of three case studies of selected excerpts from Ovid's story of Apollo and Daphne (Met. I, 456-465; 481-482; 545-552). Based on detailed linguistic and stylistic analysis of these texts, I argue that Friedman did not simply adopt a pre-existing linguistic register, but rather created an original Ovidian idiom that helped to win him lasting significance in the history of Hebrew translations from classical languages.},
  language  = {en}
}
@article{BrinkmannBeckerZimmermannetal.2022,
  author    = {Brinkmann, Kai Oliver and Becker, Tim and Zimmermann, Florian and Kreusel, Cedric and Gahlmann, Tobias and Theisen, Manuel and Haeger, Tobias and Olthof, Selina and T{\"u}ckmantel, Christian and G{\"u}nster, M. and Maschwitz, Timo and G{\"o}belsmann, Fabian and Koch, Christine and Hertel, Dirk and Caprioglio, Pietro and Pe{\~n}a-Camargo, Francisco and Perdig{\´o}n-Toro, Lorena and Al-Ashouri, Amran and Merten, Lena and Hinderhofer, Alexander and Gomell, Leonie and Zhang, Siyuan and Schreiber, Frank and Albrecht, Steve and Meerholz, Klaus and Neher, Dieter and Stolterfoht, Martin and Riedl, Thomas},
  title     = {Perovskite-organic tandem solar cells with indium oxide interconnect},
  series = {Nature},
  volume    = {604},
  journal   = {Nature},
  number    = {7905},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {0028-0836},
  doi       = {10.1038/s41586-022-04455-0},
  pages     = {280 -- 286},
  year      = {2022},
  abstract  = {Multijunction solar cells can overcome the fundamental efficiency limits of single-junction devices. The bandgap tunability of metal halide perovskite solar cells renders them attractive for multijunction architectures(1). Combinations with silicon and copper indium gallium selenide (CIGS), as well as all-perovskite tandem cells, have been reported(2-5). Meanwhile, narrow-gap non-fullerene acceptors have unlocked skyrocketing efficiencies for organic solar cells(6,7). Organic and perovskite semiconductors are an attractive combination, sharing similar processing technologies. Currently, perovskite-organic tandems show subpar efficiencies and are limited by the low open-circuit voltage (V-oc) of wide-gap perovskite cells(8) and losses introduced by the interconnect between the subcells(9,10). Here we demonstrate perovskite-organic tandem cells with an efficiency of 24.0 per cent (certified 23.1 per cent) and a high V-oc of 2.15 volts. Optimized charge extraction layers afford perovskite subcells with an outstanding combination of high V-oc and fill factor. The organic subcells provide a high external quantum efficiency in the near-infrared and, in contrast to paradigmatic concerns about limited photostability of non-fullerene cells(11), show an outstanding operational stability if excitons are predominantly generated on the non-fullerene acceptor, which is the case in our tandems. The subcells are connected by an ultrathin (approximately 1.5 nanometres) metal-like indium oxide layer with unprecedented low optical/electrical losses. This work sets a milestone for perovskite-organic tandems, which outperform the best p-i-n perovskite single junctions(12) and are on a par with perovskite-CIGS and all-perovskite multijunctions(13).},
  language  = {en}
}
@article{ZapataArteagaMarinaZuoetal.2022,
  author    = {Zapata-Arteaga, Osnat and Marina, Sara and Zuo, Guangzheng and Xu, Kai and D{\"o}rling, Bernhard and Alberto P{\´e}rez, Luis and Sebasti{\´a}n Reparaz, Juan and Mart{\´i}n, Jaime and Kemerink, Martijn and Campoy-Quiles, Mariano},
  title     = {Design rules for polymer blends with high thermoelectric performance},
  series = {Advanced energy materials},
  volume    = {12},
  journal   = {Advanced energy materials},
  number    = {19},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1614-6832},
  doi       = {10.1002/aenm.202104076},
  pages     = {11},
  year      = {2022},
  abstract  = {A combinatorial study of the effect of in-mixing of various guests on the thermoelectric properties of the host workhorse polymer poly[2,5-bis(3-tetradecylthiophen-2-yl)thieno[3,2-b]thiophene] (PBTTT) is presented. Specifically, the composition and thickness for doped films of PBTTT blended with different polymers are varied. Some blends at guest weight fractions around 10-15\% exhibit up to a fivefold increase in power factor compared to the reference material, leading to zT values around 0.1. Spectroscopic analysis of the charge-transfer species, structural characterization using grazing-incidence wide-angle X-ray scattering, differential scanning calorimetry, Raman, and atomic force microscopy, and Monte Carlo simulations are employed to determine that the key to improved performance is for the guest to promote long-range electrical connectivity and low disorder, together with similar highest occupied molecular orbital levels for both materials in order to ensure electronic connectivity are combined.},
  language  = {en}
}
@article{NiederhoferCioniSchmidtetal.2022,
  author    = {Niederhofer, Florian and Cioni, Maria-Rosa L. and Schmidt, Thomas and Bekki, Kenji and de Grijs, Richard and Ivanov, Valentin D. and Oliveira, Joana M. and Ripepi, Vincenzo and Subramanian, Smitha and van Loon, Jacco Th},
  title     = {The VMC survey - XLVI. Stellar proper motions in the centre of the Large Magellanic Cloud},
  series = {Monthly notices of the Royal Astronomical Society},
  volume    = {512},
  journal   = {Monthly notices of the Royal Astronomical Society},
  number    = {4},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0035-8711},
  doi       = {10.1093/mnras/stac712},
  pages     = {5423 -- 5439},
  year      = {2022},
  abstract  = {We present proper motion (PM) measurements within the central region of the Large Magellanic Cloud (LMC), using near-infrared data from the VISTA survey of the Magellanic Cloud system (VMC). This work encompasses 18 VMC tiles covering a total sky area of similar to 28 deg(2). We computed absolute stellar PMs from multiepoch observations in the K-s filter over time baselines between similar to 12 and 47 months. Our final catalogue contains similar to 6322 000 likely LMC member stars with derived PMs. We employed a simple flat-rotating disc model to analyse and interpret the PM data. We found a stellar centre of rotation (alpha(0) = 79.95 degrees(+0.22)(-0.23), delta(0) = -69.31 degrees(+0.12)(-0.11)) that is in agreement with that resulting from Hubble Space Telescope data. The inferred viewing angles of the LMC disc (i = 33.5 degrees(+1.2)(-1.3), Theta = 129.8 degrees(+1.9)(-1.9)) are in good agreement with values from the literature but suggest a higher inclination of the central parts of the LMC. Our data confirm a higher rotation amplitude for the young (less than or similar to 0.5 Gyr) stars compared to the intermediate-age/old (greater than or similar to 1 Gyr) population, which can be explained by asymmetric drift. We constructed spatially resolved velocity maps of the intermediate-age/old and young populations. Intermediate-age/old stars follow elongated orbits parallel to the bar's major axis, providing first observational evidence for x(1) orbits within the LMC bar. In the innermost regions, the motions show more chaotic structures. Young stars show motions along a central filamentary bar structure.},
  language  = {en}
}
@article{PeterWenderingSchlickeiseretal.2022,
  author    = {Peter, Lena and Wendering, D{\´e}sir{\´e}e Jacqueline and Schlickeiser, Stephan and Hoffmann, Henrike and Noster, Rebecca and Wagner, Dimitrios Laurin and Zarrinrad, Ghazaleh and M{\"u}nch, Sandra and Picht, Samira and Schulenberg, Sarah and Moradian, Hanieh and Mashreghi, Mir-Farzin and Klein, Oliver and Gossen, Manfred and Roch, Toralf and Babel, Nina and Reinke, Petra and Volk, Hans-Dieter and Amini, Leila and Schmueck-Henneresse, Michael},
  title     = {Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients},
  series = {Molecular therapy methods and clinical development},
  volume    = {25},
  journal   = {Molecular therapy methods and clinical development},
  publisher = {Cell Press},
  address   = {Cambridge},
  issn      = {2329-0501},
  doi       = {10.1016/j.omtm.2022.02.012},
  pages     = {52 -- 73},
  year      = {2022},
  abstract  = {Solid organ transplant (SOT) recipients receive therapeutic immunosuppression that compromises their immune response to infections and vaccines. For this reason, SOT patients have a high risk of developing severe coronavirus disease 2019 (COVID-19) and an increased risk of death from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Moreover, the efficiency of immunotherapies and vaccines is reduced due to the constant immunosuppression in this patient group. Here, we propose adoptive transfer of SARS-CoV-2-specific T cells made resistant to a common immunosuppressant, tacrolimus, for optimized performance in the immunosuppressed patient. Using a ribonucleoprotein approach of CRISPR-Cas9 technology, we have generated tacrolimus-resistant SARS-CoV-2-specific T cell products from convalescent donors and demonstrate their specificity and function through characterizations at the single-cell level, including flow cytometry, single-cell RNA (scRNA) Cellular Indexing of Transcriptomes and Epitopes (CITE), and T cell receptor (TCR) sequencing analyses. Based on the promising results, we aim for clinical validation of this approach in transplant recipients. Additionally, we propose a combinatory approach with tacrolimus, to prevent an overshooting immune response manifested as bystander T cell activation in the setting of severe COVID-19 immunopathology, and tacrolimus-resistant SARS-CoV-2-specific T cell products, allowing for efficient clearance of viral infection. Our strategy has the potential to prevent severe COVID-19 courses in SOT or autoimmunity settings and to prevent immunopathology while providing viral clearance in severe non-transplant COVID-19 cases.},
  language  = {en}
}
@article{WiemkerBunovaNeufeldetal.2022,
  author    = {Wiemker, Veronika and Bunova, Anna and Neufeld, Maria and Gornyi, Boris and Yurasova, Elena and Konigorski, Stefan and Kalinina, Anna and Kontsevaya, Anna and Ferreira-Borges, Carina and Probst, Charlotte},
  title     = {Pilot study to evaluate usability and acceptability of the 'Animated Alcohol Assessment Tool' in Russian primary healthcare},
  series = {Digital health},
  volume    = {8},
  journal   = {Digital health},
  publisher = {Sage Publications},
  address   = {London},
  issn      = {2055-2076},
  doi       = {10.1177/20552076211074491},
  pages     = {11},
  year      = {2022},
  abstract  = {Background and aims: Accurate and user-friendly assessment tools quantifying alcohol consumption are a prerequisite to effective prevention and treatment programmes, including Screening and Brief Intervention. Digital tools offer new potential in this field. We developed the 'Animated Alcohol Assessment Tool' (AAA-Tool), a mobile app providing an interactive version of the World Health Organization's Alcohol Use Disorders Identification Test (AUDIT) that facilitates the description of individual alcohol consumption via culturally informed animation features. This pilot study evaluated the Russia-specific version of the Animated Alcohol Assessment Tool with regard to (1) its usability and acceptability in a primary healthcare setting, (2) the plausibility of its alcohol consumption assessment results and (3) the adequacy of its Russia-specific vessel and beverage selection. Methods: Convenience samples of 55 patients (47\% female) and 15 healthcare practitioners (80\% female) in 2 Russian primary healthcare facilities self-administered the Animated Alcohol Assessment Tool and rated their experience on the Mobile Application Rating Scale - User Version. Usage data was automatically collected during app usage, and additional feedback on regional content was elicited in semi-structured interviews. Results: On average, patients completed the Animated Alcohol Assessment Tool in 6:38 min (SD = 2.49, range = 3.00-17.16). User satisfaction was good, with all subscale Mobile Application Rating Scale - User Version scores averaging >3 out of 5 points. A majority of patients (53\%) and practitioners (93\%) would recommend the tool to 'many people' or 'everyone'. Assessed alcohol consumption was plausible, with a low number (14\%) of logically impossible entries. Most patients reported the Animated Alcohol Assessment Tool to reflect all vessels (78\%) and all beverages (71\%) they typically used. Conclusion: High acceptability ratings by patients and healthcare practitioners, acceptable completion time, plausible alcohol usage assessment results and perceived adequacy of region-specific content underline the Animated Alcohol Assessment Tool's potential to provide a novel approach to alcohol assessment in primary healthcare. After its validation, the Animated Alcohol Assessment Tool might contribute to reducing alcohol-related harm by facilitating Screening and Brief Intervention implementation in Russia and beyond.},
  language  = {en}
}
@article{AlvaradoGomezCohenDrakeetal.2022,
  author    = {Alvarado-G{\´o}mez, Juli{\´a}n D. and Cohen, Ofer and Drake, Jeremy J. and Fraschetti, Federico and Poppenh{\"a}ger, Katja and Garraffo, Cecilia and Chebly, Judy and Ilin, Ekaterina and Harbach, Laura and Kochukhov, Oleg},
  title     = {Simulating the space weather in the AU Mic system: stellar winds and extreme coronal mass ejections},
  series = {Astrophysical journal},
  volume    = {928},
  journal   = {Astrophysical journal},
  number    = {2},
  publisher = {IOP Publishing},
  address   = {Bristol},
  issn      = {1538-4357},
  doi       = {10.3847/1538-4357/ac54b8},
  pages     = {12},
  year      = {2022},
  abstract  = {Two close-in planets have been recently found around the M-dwarf flare star AU Microscopii (AU Mic). These Neptune-sized planets (AU Mic b and c) seem to be located very close to the so-called "evaporation valley" in the exoplanet population, making this system an important target for studying atmospheric loss on exoplanets. This process, while mainly driven by high-energy stellar radiation, will be strongly mediated by the space environment surrounding the planets. Here we present an investigation of this last area, performing 3D numerical modeling of the quiescent stellar wind from AU Mic, as well as time-dependent simulations describing the evolution of a highly energetic coronal mass ejection (CME) event in this system. Observational constraints on the stellar magnetic field and properties of the eruption are incorporated in our models. We carry out qualitative and quantitative characterizations of the stellar wind, the emerging CMEs, as well as the expected steady and transient conditions along the orbit of both exoplanets. Our results predict extreme space weather for AU Mic and its planets. This includes sub-Alfvenic regions for the large majority of the exoplanet orbits, very high dynamic and magnetic pressure values in quiescence (varying within 10(2)-10(5) times the dynamic pressure experienced by Earth), and an even harsher environment during the passage of any escaping CME associated with the frequent flaring observed in AU Mic. These space weather conditions alone pose an immense challenge for the survival of exoplanetary atmospheres (if any) in this system.},
  language  = {en}
}
@article{GeistGallagherKotullaetal.2022,
  author    = {Geist, Emily and Gallagher, John S. and Kotulla, Ralf and Oskinova, Lida and Hamann, Wolf-Rainer and Ramachandran, Varsha and Sabbi, Elena and Smith, Linda J. and Kniazev, Alexey and Nota, Antonella and Rickard, Matthew J.},
  title     = {Ionization and star formation in the giant H ii region SMC-N66},
  series = {Publications of the Astronomical Society of the Pacific},
  volume    = {134},
  journal   = {Publications of the Astronomical Society of the Pacific},
  number    = {1036},
  publisher = {IOP Publishing},
  address   = {Bristol},
  issn      = {0004-6280},
  doi       = {10.1088/1538-3873/ac697b},
  pages     = {11},
  year      = {2022},
  abstract  = {The NGC 346 young stellar system and associated N66 giant H ii region in the Small Magellanic Cloud are the nearest example of a massive star-forming event in a low metallicity (Z approximate to 0.2Z (circle dot)) galaxy. With an age of less than or similar to 3 Myr this system provides a unique opportunity to study relationships between massive stars and their associated H ii region. Using archival data, we derive a total H alpha luminosity of L(H alpha) = 4.1 x 10(38) erg s(-1) corresponding to an H-photoionization rate of 3 x 10(50) s(-1). A comparison with a predicted stellar ionization rate derived from the more than 50 known O-stars in NGC 346, including massive stars recently classified from Hubble Space Telescope far-ultraviolet (FUV) spectra, indicates an approximate ionization balance. Spectra obtained with SALT suggest the ionization structure of N66 could be consistent with some leakage of ionizing photons. Due to the low metallicity, the FUV luminosity from NGC 346 is not confined to the interstellar cloud associated with N66. Ionization extends through much of the spatial extent of the N66 cloud complex, and most of the cloud mass is not ionized. The stellar mass estimated from nebular L(H alpha) appears to be lower than masses derived from the census of resolved stars which may indicate a disconnect between the formation of high and low mass stars in this region. We briefly discuss implications of the properties of N66 for studies of star formation and stellar feedback in low metallicity environments.},
  language  = {en}
}
@article{PerottoniLimbergAmaranteetal.2022,
  author    = {Perottoni, H{\´e}lio D. and Limberg, Guilherme and Amarante, Jo{\~a}o A. S. and Rossi, Silvia and Queiroz, Anna B. A. and Santucci, Rafael M. and P{\´e}rez-Villegas, Angeles and Chiappini, Cristina},
  title     = {The unmixed debris of Gaia-Sausage/Enceladus in the form of a pair of halo stellar overdensities},
  series = {Astrophysical journal letters},
  volume    = {936},
  journal   = {Astrophysical journal letters},
  number    = {1},
  publisher = {IOP Publishing},
  address   = {Bristol},
  issn      = {2041-8213},
  doi       = {10.3847/2041-8213/ac88d6},
  pages     = {7},
  year      = {2022},
  abstract  = {In the first billion years after its formation, the galaxy underwent several mergers with dwarf satellites of various masses. The debris of Gaia-Sausage/Enceladus (GSE), the galaxy responsible for the last significant merger of the Milky Way, dominates the inner halo and has been suggested to be the progenitor of both the Hercules-Aquila Cloud (HAC) and Virgo Overdensity (VOD). We combine SEGUE, APOGEE, Gaia, and StarHorse distances to characterize the chemodynamical properties and verify the link between HAC, VOD, and GSE. We find that the orbital eccentricity distributions of the stellar overdensities and GSE are comparable. We also find that they have similar, strongly peaked, metallicity distribution functions, reinforcing the hypothesis of common origin. Furthermore, we show that HAC and VOD are indistinguishable from the prototypical GSE population within all chemical-abundance spaces analyzed. All these evidences combined provide a clear demonstration that the GSE merger is the main progenitor of the stellar populations found within these halo overdensities.},
  language  = {en}
}
@article{XuGiannettiSugiyamaetal.2022,
  author    = {Xu, Huizhen and Giannetti, Alessandro and Sugiyama, Yuki and Zheng, Wenna and Schneider, Ren{\´e} and Watanabe, Yoichiro and Oda, Yoshihisa and Persson, Staffan},
  title     = {Secondary cell wall patterning-connecting the dots, pits and helices},
  series = {Open biology},
  volume    = {12},
  journal   = {Open biology},
  number    = {5},
  publisher = {Royal Society},
  address   = {London},
  issn      = {2046-2441},
  doi       = {10.1098/rsob.210208},
  pages     = {18},
  year      = {2022},
  abstract  = {All plant cells are encased in primary cell walls that determine plant morphology, but also protect the cells against the environment. Certain cells also produce a secondary wall that supports mechanically demanding processes, such as maintaining plant body stature and water transport inside plants. Both these walls are primarily composed of polysaccharides that are arranged in certain patterns to support cell functions. A key requisite for patterned cell walls is the arrangement of cortical microtubules that may direct the delivery of wall polymers and/or cell wall producing enzymes to certain plasma membrane locations. Microtubules also steer the synthesis of cellulose-the load-bearing structure in cell walls-at the plasma membrane. The organization and behaviour of the microtubule array are thus of fundamental importance to cell wall patterns. These aspects are controlled by the coordinated effort of small GTPases that probably coordinate a Turing's reaction-diffusion mechanism to drive microtubule patterns. Here, we give an overview on how wall patterns form in the water-transporting xylem vessels of plants. We discuss systems that have been used to dissect mechanisms that underpin the xylem wall patterns, emphasizing the VND6 and VND7 inducible systems, and outline challenges that lay ahead in this field.},
  language  = {en}
}
@article{HagoortVuillermeHortobagyietal.2022,
  author    = {Hagoort, Iris and Vuillerme, Nicolas and Hortob{\´a}gyi, Tibor and Lamoth, Claudine J. C.},
  title     = {Outcome-dependent effects of walking speed and age on quantitative and qualitative gait measures},
  series = {Gait \& posture},
  volume    = {93},
  journal   = {Gait \& posture},
  publisher = {Elsevier},
  address   = {Clare},
  issn      = {0966-6362},
  doi       = {10.1016/j.gaitpost.2022.01.001},
  pages     = {39 -- 46},
  year      = {2022},
  abstract  = {Background: Walking speed predicts many clinical outcomes in old age. However, a comprehensive assessment of how walking speed affects accelerometer based quantitative and qualitative gait measures in younger and older adults is lacking. Research question: What is the relationship between walking speed and quantitative and qualitative gait outcomes in younger and older adults? Methods: Younger (n = 27, age: 21.6) and older participants (n = 27, age: 69.5) completed 340 steps on a treadmill at speeds of 0.70 to a maximum of 1.75 m.s(-1). We used generalized additive mixed models to determine the relationship between walking speed and quantitative (stride length, stride time, stride frequency and their variability) and qualitative (stride regularity, stability, smoothness, symmetry, synchronization, predictability) gait measures extracted from trunk accelerations. Results: The type of relationship between walking speed and the majority of gait measures (quantitative and qualitative) was characterized as logarithmic, with more prominent speed-effects at speeds below 1.20 m.s(-1). Changes in quantitative measures included shorter strides, longer stride times, and a lower stride frequency, with more variability at lower speeds independent of age. For qualitative measures, we found a decrease in gait symmetry, stability and regularity in all directions with decreasing speeds, a decrease in gait predictability (Vertical, V, anterior-posterior, AP) and stronger gait synchronization (AP-mediolateral, ML, AP-V), and direction dependent effects of gait smoothness, which decreased in V direction, but increased in AP and ML directions with decreasing speeds. We found outcome-dependent effects of age on the quantitative and qualitative gait measures, with either no differences between age-groups, age-related differences that existed regardless of speed, and age-related differences in the type of relationship with walking speed. Significance: The relationship between walking speed and quantitative and qualitative gait measures, and the effects of age on this relationship, depends on the type of gait measure studied.},
  language  = {en}
}
@article{CabiecesOlivar‐CastanoJunqueiraetal.2022,
  author    = {Cabieces, Roberto and Olivar-Casta{\~n}o, Andr{\´e}s and Junqueira, Thiago C. and Relinque, Jes{\´u}s and Fernandez-Prieto, Luis M. and Vack{\´a}r, Jiř{\´i} and R{\"o}sler, Boris and Barco, Jaime and Pazos, Antonio and Garc{\´i}a-Mart{\´i}nez, Luz},
  title     = {Integrated Seismic Program (ISP): A new Python GUI-based software for earthquake seismology and seismic signal processing},
  series = {Seismological research letters},
  volume    = {93},
  journal   = {Seismological research letters},
  number    = {3},
  publisher = {Seismological Society of America},
  address   = {Albany},
  issn      = {0895-0695},
  doi       = {10.1785/0220210205},
  pages     = {1895 -- 1908},
  year      = {2022},
  abstract  = {Integrated Seismic Program (ISP) is a graphical user interface designed to facilitate and provide a user-friendly framework for performing diverse common and advanced tasks in seismological research. ISP is composed of five main modules for earthquake location, time-frequency analysis and advanced signal processing, implementation of array techniques to estimate the slowness vector, seismic moment tensor inversion, and receiver function computation and analysis. In addition, several support tools are available, allowing the user to create an event database, download data from International Federation of Digital Seismograph Networks services, inspect the background noise, and compute synthetic seismograms. ISP is written in Python3, supported by several open-source and/or publicly available tools. Its modular design allows for new features to be added in a collaborative development environment.},
  language  = {en}
}
@article{TabatabaeiAlseekhShahidetal.2022,
  author    = {Tabatabaei, Iman and Alseekh, Saleh and Shahid, Mohammad and Leniak, Ewa and Wagner, Mateusz and Mahmoudi, Henda and Thushar, Sumitha and Fernie, Alisdair R. and Murphy, Kevin M. and Schm{\"o}ckel, Sandra M. and Tester, Mark and M{\"u}ller-R{\"o}ber, Bernd and Skirycz, Aleksandra and Balazadeh, Salma},
  title     = {The diversity of quinoa morphological traits and seed metabolic composition},
  series = {Scientific data},
  volume    = {9},
  journal   = {Scientific data},
  number    = {1},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2052-4463},
  doi       = {10.1038/s41597-022-01399-y},
  pages     = {7},
  year      = {2022},
  abstract  = {Quinoa (Chenopodium quinoa Willd.) is an herbaceous annual crop of the amaranth family (Amaranthaceae). It is increasingly cultivated for its nutritious grains, which are rich in protein and essential amino acids, lipids, and minerals. Quinoa exhibits a high tolerance towards various abiotic stresses including drought and salinity, which supports its agricultural cultivation under climate change conditions. The use of quinoa grains is compromised by anti-nutritional saponins, a terpenoid class of secondary metabolites deposited in the seed coat; their removal before consumption requires extensive washing, an economically and environmentally unfavorable process; or their accumulation can be reduced through breeding. In this study, we analyzed the seed metabolomes, including amino acids, fatty acids, and saponins, from 471 quinoa cultivars, including two related species, by liquid chromatography - mass spectrometry. Additionally, we determined a large number of agronomic traits including biomass, flowering time, and seed yield. The results revealed considerable diversity between genotypes and provide a knowledge base for future breeding or genome editing of quinoa.},
  language  = {en}
}
@article{BlanchardPetitgirardLaurenzetal.2022,
  author    = {Blanchard, Ingrid and Petitgirard, Sylvain and Laurenz, Vera and Miyajima, Nobuyoshi and Wilke, Max and Rubie, David C. and Lobanov, Sergey S. and Hennet, Louis and Morgenroth, Wolfgang and Tucoulou, R{\´e}mi and Bonino, Valentina and Zhao, Xuchao and Franchi, Ian},
  title     = {Chemical analysis of trace elements at the nanoscale in samples recovered from laser-heated diamond anvil cell experiments},
  series = {Physics and chemistry of minerals},
  volume    = {49},
  journal   = {Physics and chemistry of minerals},
  number    = {6},
  publisher = {Springer},
  address   = {New York},
  issn      = {0342-1791},
  doi       = {10.1007/s00269-022-01193-7},
  pages     = {16},
  year      = {2022},
  abstract  = {High pressure and high temperature experiments performed with laser-heated diamond anvil cells (LH-DAC) are being extensively used in geosciences to study matter at conditions prevailing in planetary interiors. Due to the size of the apparatus itself, the samples that are produced are extremely small, on the order of few tens of micrometers. There are several ways to analyze the samples and extract physical, chemical or structural information, using either in situ or ex situ methods. In this paper, we compare two nanoprobe techniques, namely nano-XRF and NanoSIMS, that can be used to analyze recovered samples synthetized in a LH-DAC. With these techniques, it is possible to extract the spatial distribution of chemical elements in the samples. We show the results for several standards and discuss the importance of proper calibration for the acquisition of quantifiable results. We used these two nanoprobe techniques to retrieve elemental ratios of dilute species (few tens of ppm) in quenched experimental molten samples relevant for the formation of the iron-rich core of the Earth. We finally discuss the applications of such probes to constrain the partitioning of trace elements between metal and silicate phases, with a focus on moderately siderophile elements, tungsten and molybdenum.},
  language  = {en}
}
@article{StojkoskiJolakoskiPaletal.2022,
  author    = {Stojkoski, Viktor and Jolakoski, Petar and Pal, Arnab and Sandev, Trifce and Kocarev, Ljupco and Metzler, Ralf},
  title     = {Income inequality and mobility in geometric Brownian motion with stochastic resetting: theoretical results and empirical evidence of non-ergodicity},
  series = {Philosophical transactions of the Royal Society A: Mathematical, physical and engineering sciences},
  volume    = {380},
  journal   = {Philosophical transactions of the Royal Society A: Mathematical, physical and engineering sciences},
  number    = {2224},
  publisher = {Royal Society},
  address   = {London},
  issn      = {1364-503X},
  doi       = {10.1098/rsta.2021.0157},
  pages     = {17},
  year      = {2022},
  abstract  = {We explore the role of non-ergodicity in the relationship between income inequality, the extent of concentration in the income distribution, and income mobility, the feasibility of an individual to change their position in the income rankings. For this purpose, we use the properties of an established model for income growth that includes 'resetting' as a stabilizing force to ensure stationary dynamics. We find that the dynamics of inequality is regime-dependent: it may range from a strictly non-ergodic state where this phenomenon has an increasing trend, up to a stable regime where inequality is steady and the system efficiently mimics ergodicity. Mobility measures, conversely, are always stable over time, but suggest that economies become less mobile in non-ergodic regimes. By fitting the model to empirical data for the income share of the top earners in the USA, we provide evidence that the income dynamics in this country is consistently in a regime in which non-ergodicity characterizes inequality and immobility. Our results can serve as a simple rationale for the observed real-world income dynamics and as such aid in addressing non-ergodicity in various empirical settings across the globe.This article is part of the theme issue 'Kinetic exchange models of societies and economies'.},
  language  = {en}
}
@article{BuschKuboschBendauetal.2022,
  author    = {Busch, Aglaja and Kubosch, Eva Johanna and Bendau, Antonia and Leonhart, Rainer and Meidl, Verena and Bretthauer, Berit and Petzold, Moritz Bruno and Dallmann, Petra and Wrobel, Nina and Plag, Jens and Str{\"o}hle, Andreas and Hirschm{\"u}ller, Anja},
  title     = {Mental health in German paralympic athletes during the 1st year of the COVID-19 pandemic compared to a general population sample},
  series = {Frontiers in sports and active living},
  volume    = {4},
  journal   = {Frontiers in sports and active living},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2624-9367},
  doi       = {10.3389/fspor.2022.870692},
  pages     = {9},
  year      = {2022},
  abstract  = {IntroductionThe COVID-19 pandemic has huge influences on daily life and is not only associated with physical but also with major psychological impacts. Mental health problems and disorders are frequently present in elite paralympic athletes. Due to the pandemic situation, new stressors (e.g., loss of routine, financial insecurity) might act upon the athletes. Therefore, the assessment of mental health in athletes during the COVID-19 pandemic is important to identify prevalence of psychological problems and propose countermeasures. MethodsThe mental health of German paralympic athletes was longitudinally monitored (starting in May 2019). The athletes completed the Patient Health Questionnaire 4 (PHQ-4) on a weekly basis and reported a stress level, training hours, and training load. During the pandemic, 8 measurement time points (March 2020 to April 2021) were used to reflect the psychological health course of the athletes. In parallel, a convenience sample of the general population was questioned about their psychological distress, including the PHQ-4. To be included in the analysis, participants of both groups had to complete at least 4 measurement time points. Matching of the para-athletes and the general population sample was prioritized upon completion of the same measurement time points, gender, and age. ResultsSeventy-eight paralympic athletes (40 women, 38 men, age: 29.8 +/- 11.4 years) met the inclusion criteria. Seventy-eight matched pairs of the general population (40 women; 38 men; age: 30.5 +/- 10.9 years) were identified. The para-athletes had a significantly (p r <0.48) lower PHQ-4 value at each measurement time point compared to the matched control group. No significant age or sex differences were evident regarding the symptom burden. In para-athletes, no significant and a weak positive correlation was found between decreased training load and PHQ-4 values and a stress level, respectively. Reduced physical activity was significantly (p <0.0001) associated with higher PHQ-4 values in the general population sample. DiscussionLower PHQ-4 values were reported by the para-athletes compared to the general population sample. However, small sample sizes must be considered while interpreting the data. Nevertheless, adequate support for individuals suffering from severe psychopathological symptoms should be provided for para-athletes as well as for the general population.},
  language  = {en}
}
@article{SchwiederWesemeyerFrantzetal.2022,
  author    = {Schwieder, Marcel and Wesemeyer, Maximilian and Frantz, David and Pfoch, Kira and Erasmi, Stefan and Pickert, J{\"u}rgen and Nendel, Claas and Hostert, Patrick},
  title     = {Mapping grassland mowing events across Germany based on combined Sentinel-2 and Landsat 8 time series},
  series = {Remote sensing of environment},
  volume    = {269},
  journal   = {Remote sensing of environment},
  publisher = {Elsevier},
  address   = {New York},
  issn      = {0034-4257},
  doi       = {10.1016/j.rse.2021.112795},
  pages     = {16},
  year      = {2022},
  abstract  = {Spatially explicit knowledge on grassland extent and management is critical to understand and monitor the impact of grassland use intensity on ecosystem services and biodiversity. While regional studies allow detailed insights into land use and ecosystem service interactions, information on a national scale can aid biodiversity assessments. However, for most European countries this information is not yet widely available. We used an analysis-ready-data cube that contains dense time series of co-registered Sentinel-2 and Landsat 8 data, covering the extent of Germany. We propose an algorithm that detects mowing events in the time series based on residuals from an assumed undisturbed phenology, as an indicator of grassland use intensity. A self-adaptive ruleset enabled to account for regional variations in land surface phenology and non-stationary time series on a pixelbasis. We mapped mowing events for the years from 2017 to 2020 for permanent grassland areas in Germany. The results were validated on a pixel level in four of the main natural regions in Germany based on reported mowing events for a total of 92 (2018) and 78 (2019) grassland parcels. Results for 2020 were evaluated with combined time series of Landsat, Sentinel-2 and PlanetScope data. The mean absolute percentage error between detected and reported mowing events was on average 40\% (2018), 36\% (2019) and 35\% (2020). Mowing events were on average detected 11 days (2018), 7 days (2019) and 6 days (2020) after the reported mowing. Performance measures varied between the different regions of Germany, and lower accuracies were found in areas that are revisited less frequently by Sentinel-2. Thus, we assessed the influence of data availability and found that the detection of mowing events was less influenced by data availability when at least 16 cloud-free observations were available in the grassland season. Still, the distribution of available observations throughout the season appeared to be critical. On a national scale our results revealed overall higher shares of less intensively mown grasslands and smaller shares of highly intensively managed grasslands. Hotspots of the latter were identified in the alpine foreland in Southern Germany as well as in the lowlands in the Northwest of Germany. While these patterns were stable throughout the years, the results revealed a tendency to lower management intensity in the extremely dry year 2018. Our results emphasize the ability of the approach to map the intensity of grassland management throughout large areas despite variations in data availability and environmental conditions.},
  language  = {en}
}
@article{LiShenZhangetal.2022,
  author    = {Li, Jian and Shen, Jinhua and Zhang, Xiaoli and Peng, Yangqin and Zhang, Qin and Hu, Liang and Reichetzeder, Christoph and Zeng, Suimin and Li, Jing and Tian, Mei and Gong, Fei and Lin, Ge and Hocher, Berthold},
  title     = {Risk factors associated with preterm birth after IVF/ICSI},
  series = {Scientific reports},
  volume    = {12},
  journal   = {Scientific reports},
  number    = {1},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-022-12149-w},
  pages     = {9},
  year      = {2022},
  abstract  = {In vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) is associated with an increased risk of preterm (33rd-37th gestational week) and early preterm birth (20th-32nd gestational week). The underlying general and procedure related risk factors are not well understood so far. 4328 infertile women undergoing IVF/ICSI were entered into this study. The study population was divided into three groups: (a) early preterm birth group (n = 66), (b) preterm birth group (n = 675) and (c) full-term birth group (n = 3653). Odds for preterm birth were calculated by stepwise multivariate logistic regression analysis. We identified seven independent risk factors for preterm birth and four independent risk factors for early preterm birth. Older (> 39) or younger (< 25) maternal age (OR: 1.504, 95\% CI 1.108-2.042, P = 0.009; OR: 2.125, 95\% CI 1.049-4.304, P = 0.036, respectively), multiple pregnancy (OR: 9.780, 95\% CI 8.014-11.935, P < 0.001; OR: 8.588, 95\% CI 4.866-15.157, P < 0.001, respectively), placenta previa (OR: 14.954, 95\% CI 8.053-27.767, P < 0.001; OR: 16.479, 95\% CI 4.381-61.976, P < 0.001, respectively), and embryo reduction (OR: 3.547, 95\% CI 1.736-7.249, P = 0.001; OR: 7.145, 95\% CI 1.990-25.663, P = 0.003, respectively) were associated with preterm birth and early preterm birth, whereas gestational hypertension (OR: 2.494, 95\% CI 1.770-3.514, P < 0.001), elevated triglycerides (OR: 1.120, 95\% CI 1.011-1.240, P = 0.030) and shorter activated partial thromboplastin time (OR: 0.967, 95\% CI 0.949-0.985, P < 0.001) were associated only with preterm birth. In conclusion, preterm and early preterm birth risk factors in patients undergoing assisted IVF/ICSI are in general similar to those in natural pregnancy. The lack of some associations in the early preterm group was most likely due to the lower number of early preterm birth cases. Only embryo reduction represents an IVF/ICSI specific risk factor.},
  language  = {en}
}