@article{AyBrysonWeckKuehne2022, author = {Ay-Bryson, Destina Sevde and Weck, Florian and K{\"u}hne, Franziska}, title = {Can simulated patient encounters appear authentic?}, series = {Training and education in professional psychology}, volume = {16}, journal = {Training and education in professional psychology}, number = {1}, publisher = {American Psychological Association}, address = {Washington}, issn = {1931-3918}, doi = {10.1037/tep0000349}, pages = {20 -- 27}, year = {2022}, abstract = {Public Significance Statement This study demonstrates that simulated patients (SPs) can authentically portray a depressive case. The results provide preliminary evidence of psychometrically sound properties of the rating scale that contributes to distinguishing between authentic and unauthentic SPs and may thus foster SPs' dissemination into evidence-based training.
For training purposes, simulated patients (SPs), that is, healthy people portraying a disorder, are disseminating more into clinical psychology and psychotherapy. In the current study, we developed an observer-based rating instrument for the evaluation of SP authenticity-namely, it not being possible to distinguish them from real patients-so as to foster their use in evidence-based training. We applied a multistep inductive approach to develop the Authenticity of Patient Demonstrations (APD) scale. Ninety-seven independent psychotherapy trainees, 77.32\% female, mean age of 31.49 (SD = 5.17) years, evaluated the authenticity of 2 independent SPs, each of whom portrayed a depressive patient. The APD demonstrated good internal consistency (Cronbach's alpha = .83) and a strong correlation (r = .82) with an established tool for assessing SP performance in medical contexts. The APD scale distinguished significantly between an authentic and unauthentic SP (d = 2.35). Preliminary evidence for the psychometric properties of the APD indicates that the APD could be a viable tool for recruiting, training, and evaluating the authenticity of SPs. Strengths, limitations, and future directions are also discussed in detail.}, language = {en} } @article{Eccard2022, author = {Eccard, Jana}, title = {Can rolling composite wildflower blocks increase biodiversity in agricultural landscapes better than wildflowers strips?}, series = {Journal of applied ecology : an official journal of the British Ecological Society}, volume = {59}, journal = {Journal of applied ecology : an official journal of the British Ecological Society}, number = {5}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {0021-8901}, doi = {10.1111/1365-2664.14147}, pages = {1172 -- 1177}, year = {2022}, abstract = {Biodiversity and abundance of wildlife has dramatically declined in agricultural landscapes. Sown, short-lived wildflower (WF) strips along the margins of crop fields are a widespread and often subsidised in agri-environmental schemes, intended to enhance biodiversity, provide refuges for wild plant and arthropod populations and to provide ecosystem services to crops. Meanwhile, WF elements are also criticised, since their functionality decreases with plant succession, the removal of aged WF strip poses an ecological trap for the attracted arthropod populations and only common and mobile species benefit. Further, insects in WF strips are impacted by pesticides from agricultural fields due to shared boundaries with crop fields and by edge effects. The performance of the measure could be improved by combining several WF strips of different successional stages, each harbouring a unique community of plants and arthropods, into persistent, composite WF block, where successional stages exist in parallel. Monitoring data on many taxa in the literature shows, that a third of species are temporarily present in an ageing WF stip, thus offering composite WF blocks should increase cumulative species richness by 28\%-39\% compared to annual richness in WF strips. Persistence of composite WF blocks would offer reliable refuge for animal and plant populations, also supporting their predators and herbivores. Further, WF blocks have less boundaries to crops compared to WF strips of the same area, and are less impacted by edge effects and pesticides. Policy implications. Here I suggest a change of conservation practice changing from successional WF strips to composite WF blocks. By regular removal and replacement of aged WF strips either within the block (rotational) or at its margins (rolling), the habitat heterogeneity in composite WF block could be perpetuated. Rolling composite WF blocks change locations over years, and the original location can be reconverted to arable land while a nearby WF block is still available to wildlife. A change in agricultural schemes would be necessary, since in some European countries clustered WF strips are explicitly not subsidised.}, language = {en} } @article{NegyesiHortobagyiHilletal.2022, author = {Negyesi, Janos and Hortobagyi, Tibor and Hill, Jessica and Granacher, Urs and Nagatomi, Ryoichi}, title = {Can compression garments reduce the deleterious effects of physical exercise on muscle strength?}, series = {Sports medicine}, volume = {52}, journal = {Sports medicine}, number = {9}, publisher = {Springer}, address = {Northcote}, issn = {0112-1642}, doi = {10.1007/s40279-022-01681-4}, pages = {2159 -- 2175}, year = {2022}, abstract = {Background The use of compression garments (CGs) during or after training and competition has gained popularity in the last few decades. However, the data concerning CGs' beneficial effects on muscle strength-related outcomes after physical exercise remain inconclusive. Objective The aim was to determine whether wearing CGs during or after physical exercise would facilitate the recovery of muscle strength-related outcomes. Methods A systematic literature search was conducted across five databases (PubMed, SPORTDiscus, Web of Science, Scopus, and EBSCOhost). Data from 19 randomized controlled trials (RCTs) including 350 healthy participants were extracted and meta-analytically computed. Weighted between-study standardized mean differences (SMDs) with respect to their standard errors (SEs) were aggregated and corrected for sample size to compute overall SMDs. The type of physical exercise, the body area and timing of CG application, and the time interval between the end of the exercise and subsequent testing were assessed. Results CGs produced no strength-sparing effects (SMD [95\% confidence interval]) at the following time points (t) after physical exercise: immediately <= t < 24 h: - 0.02 (- 0.22 to 0.19), p = 0.87; 24 <= t < 48 h: - 0.00 (- 0.22 to 0.21), p = 0.98; 48 <= t < 72 h: - 0.03 (- 0.43 to 0.37), p = 0.87; 72 <= t < 96 h: 0.14 (- 0.21 to 0.49), p = 0.43; 96 h <= t: 0.26 (- 0.33 to 0.85), p = 0.38. The body area where the CG was applied had no strength-sparing effects. CGs revealed weak strength-sparing effects after plyometric exercise. Conclusion Meta-analytical evidence suggests that wearing a CG during or after training does not seem to facilitate the recovery of muscle strength following physical exercise. Practitioners, athletes, coaches, and trainers should reconsider the use of CG as a tool to reduce the effects of physical exercise on muscle strength.}, language = {en} } @article{NievasPilzPrehnetal.2022, author = {Nievas, Cecilia and Pilz, Marco and Prehn, Karsten and Schorlemmer, Danijel and Weatherill, Graeme and Cotton, Fabrice}, title = {Calculating earthquake damage building by building}, series = {Bulletin of earthquake engineering : official publication of the European Association for Earthquake Engineering}, volume = {20}, journal = {Bulletin of earthquake engineering : official publication of the European Association for Earthquake Engineering}, number = {3}, publisher = {Springer}, address = {Dordrecht}, issn = {1570-761X}, doi = {10.1007/s10518-021-01303-w}, pages = {1519 -- 1565}, year = {2022}, abstract = {The creation of building exposure models for seismic risk assessment is frequently challenging due to the lack of availability of detailed information on building structures. Different strategies have been developed in recent years to overcome this, including the use of census data, remote sensing imagery and volunteered graphic information (VGI). This paper presents the development of a building-by-building exposure model based exclusively on openly available datasets, including both VGI and census statistics, which are defined at different levels of spatial resolution and for different moments in time. The initial model stemming purely from building-level data is enriched with statistics aggregated at the neighbourhood and city level by means of a Monte Carlo simulation that enables the generation of full realisations of damage estimates when using the exposure model in the context of an earthquake scenario calculation. Though applicable to any other region of interest where analogous datasets are available, the workflow and approach followed are explained by focusing on the case of the German city of Cologne, for which a scenario earthquake is defined and the potential damage is calculated. The resulting exposure model and damage estimates are presented, and it is shown that the latter are broadly consistent with damage data from the 1978 Albstadt earthquake, notwithstanding the differences in the scenario. Through this real-world application we demonstrate the potential of VGI and open data to be used for exposure modelling for natural risk assessment, when combined with suitable knowledge on building fragility and accounting for the inherent uncertainties.}, language = {en} } @article{WeaverHeinzelJorgensenetal.2022, author = {Weaver, Catherine and Heinzel, Mirko and Jorgensen, Samantha and Flores, Joseph}, title = {Bureaucratic representation in the IMF and the World Bank}, series = {Global perspectives}, volume = {3}, journal = {Global perspectives}, number = {1}, publisher = {University of California Press}, address = {Oakland, CA}, issn = {2575-7350}, doi = {10.1525/gp.2022.39684}, pages = {18}, year = {2022}, abstract = {The legitimacy and effectiveness of international organizations are often linked directly to issues of representation—not only on their high-level governing boards and in top leadership but also within their staff. This article explores two key questions of bureaucratic representation in the critical cases of the International Monetary Fund and World Bank. First, we seek to unpack three essential dimensions of staff representation—nationality, education, and gender—to explain how representation may matter for international organizations. Second, we aim to describe the multiple dimensions of representation in the International Monetary Fund and the World Bank over the past twenty years by deploying a novel dataset on staff demographics, focusing on ranks with decision-making authority within the institutions. Our descriptive analysis reveals that the International Monetary Fund and the World Bank have made considerable efforts to diversify their bureaucracies. Nonetheless, representation remains uneven; for example, nationals from middle- and low-income countries, women, and staff without economics degrees from prominent US- or UK-based universities are less present in key leadership positions. These results may be well explained by the particular needs of the institutions' technical mandates and limits in the supply of qualified staff and, as such, need not be seen as suboptimal. Nonetheless, perceived imbalances in representation may continue to pose external legitimation and operational challenges to the International Monetary Fund and the World Bank in a complex political environment where such multidimensional representation is important to sustaining the buy-in of donor and borrower countries alike. To this end, we recommend that the International Monetary Fund and the World Bank enhance their diversity and inclusion efforts by increasing transparency via reporting disaggregated data on workforce composition and introducing annual requirements to publish progress reports with management feedback to strengthen internal and external accountability.}, language = {en} } @article{WarcholdPradhanThapaetal.2022, author = {Warchold, Anne and Pradhan, Prajal and Thapa, Pratibha and Putra, Muhammad Panji Islam Fajar and Kropp, J{\"u}rgen}, title = {Building a unified sustainable development goal database}, series = {Sustainable development}, journal = {Sustainable development}, publisher = {Wiley}, address = {Hoboken}, issn = {0968-0802}, doi = {10.1002/sd.2316}, pages = {16}, year = {2022}, abstract = {The 2020s are an essential decade for achieving the 2030 Agenda and its Sustainable Development Goals (SDGs). For this, SDG research needs to provide evidence that can be translated into concrete actions. However, studies use different SDG data, resulting in incomparable findings. Researchers primarily use SDG databases provided by the United Nations (UN), the World Bank Group (WBG), and the Bertelsmann Stiftung \& Sustainable Development Solutions Network (BE-SDSN). We compile these databases into one unified SDG database and examine the effects of the data selection on our understanding of SDG interactions. Among the databases, we observed more different than similar SDG interactions. Differences in synergies and trade-offs mainly occur for SDGs that are environmentally oriented. Due to the increased data availability, the unified SDG database offers a more nuanced and reliable view of SDG interactions. Thus, the SDG data selection may lead to diverse findings, fostering actions that might neglect or exacerbate trade-offs.}, language = {en} } @article{RichlySchlosserBoissier2022, author = {Richly, Keven and Schlosser, Rainer and Boissier, Martin}, title = {Budget-conscious fine-grained configuration optimization for spatio-temporal applications}, series = {Proceedings of the VLDB Endowment}, volume = {15}, journal = {Proceedings of the VLDB Endowment}, number = {13}, publisher = {Association for Computing Machinery (ACM)}, address = {[New York]}, issn = {2150-8097}, doi = {10.14778/3565838.3565858}, pages = {4079 -- 4092}, year = {2022}, abstract = {Based on the performance requirements of modern spatio-temporal data mining applications, in-memory database systems are often used to store and process the data. To efficiently utilize the scarce DRAM capacities, modern database systems support various tuning possibilities to reduce the memory footprint (e.g., data compression) or increase performance (e.g., additional indexes). However, the selection of cost and performance balancing configurations is challenging due to the vast number of possible setups consisting of mutually dependent individual decisions. In this paper, we introduce a novel approach to jointly optimize the compression, sorting, indexing, and tiering configuration for spatio-temporal workloads. Further, we consider horizontal data partitioning, which enables the independent application of different tuning options on a fine-grained level. We propose different linear programming (LP) models addressing cost dependencies at different levels of accuracy to compute optimized tuning configurations for a given workload and memory budgets. To yield maintainable and robust configurations, we extend our LP-based approach to incorporate reconfiguration costs as well as a worst-case optimization for potential workload scenarios. Further, we demonstrate on a real-world dataset that our models allow to significantly reduce the memory footprint with equal performance or increase the performance with equal memory size compared to existing tuning heuristics.}, language = {en} } @article{IrobBlaumBaldaufetal.2022, author = {Irob, Katja and Blaum, Niels and Baldauf, Selina and Kerger, Leon and Strohbach, Ben and Kanduvarisa, Angelina and Lohmann, Dirk and Tietjen, Britta}, title = {Browsing herbivores improve the state and functioning of savannas}, series = {Ecology and evolution}, volume = {12}, journal = {Ecology and evolution}, number = {3}, publisher = {Wiley}, address = {Hoboken}, issn = {2045-7758}, doi = {10.1002/ece3.8715}, pages = {19}, year = {2022}, abstract = {Changing climatic conditions and unsustainable land use are major threats to savannas worldwide. Historically, many African savannas were used intensively for livestock grazing, which contributed to widespread patterns of bush encroachment across savanna systems. To reverse bush encroachment, it has been proposed to change the cattle-dominated land use to one dominated by comparatively specialized browsers and usually native herbivores. However, the consequences for ecosystem properties and processes remain largely unclear. We used the ecohydrological, spatially explicit model EcoHyD to assess the impacts of two contrasting, herbivore land-use strategies on a Namibian savanna: grazer- versus browser-dominated herbivore communities. We varied the densities of grazers and browsers and determined the resulting composition and diversity of the plant community, total vegetation cover, soil moisture, and water use by plants. Our results showed that plant types that are less palatable to herbivores were best adapted to grazing or browsing animals in all simulated densities. Also, plant types that had a competitive advantage under limited water availability were among the dominant ones irrespective of land-use scenario. Overall, the results were in line with our expectations: under high grazer densities, we found heavy bush encroachment and the loss of the perennial grass matrix. Importantly, regardless of the density of browsers, grass cover and plant functional diversity were significantly higher in browsing scenarios. Browsing herbivores increased grass cover, and the higher total cover in turn improved water uptake by plants overall. We concluded that, in contrast to grazing-dominated land-use strategies, land-use strategies dominated by browsing herbivores, even at high herbivore densities, sustain diverse vegetation communities with high cover of perennial grasses, resulting in lower erosion risk and bolstering ecosystem services.}, language = {en} } @article{WulffBuschhueterWestphaletal.2022, author = {Wulff, Peter and Buschh{\"u}ter, David and Westphal, Andrea and Mientus, Lukas and Nowak, Anna and Borowski, Andreas}, title = {Bridging the gap between qualitative and quantitative assessment in science education research with machine learning}, series = {Journal of science education and technology}, volume = {31}, journal = {Journal of science education and technology}, number = {4}, publisher = {Springer}, address = {Dordrecht}, issn = {1059-0145}, doi = {10.1007/s10956-022-09969-w}, pages = {490 -- 513}, year = {2022}, abstract = {Science education researchers typically face a trade-off between more quantitatively oriented confirmatory testing of hypotheses, or more qualitatively oriented exploration of novel hypotheses. More recently, open-ended, constructed response items were used to combine both approaches and advance assessment of complex science-related skills and competencies. For example, research in assessing science teachers' noticing and attention to classroom events benefitted from more open-ended response formats because teachers can present their own accounts. Then, open-ended responses are typically analyzed with some form of content analysis. However, language is noisy, ambiguous, and unsegmented and thus open-ended, constructed responses are complex to analyze. Uncovering patterns in these responses would benefit from more principled and systematic analysis tools. Consequently, computer-based methods with the help of machine learning and natural language processing were argued to be promising means to enhance assessment of noticing skills with constructed response formats. In particular, pretrained language models recently advanced the study of linguistic phenomena and thus could well advance assessment of complex constructs through constructed response items. This study examines potentials and challenges of a pretrained language model-based clustering approach to assess preservice physics teachers' attention to classroom events as elicited through open-ended written descriptions. It was examined to what extent the clustering approach could identify meaningful patterns in the constructed responses, and in what ways textual organization of the responses could be analyzed with the clusters. Preservice physics teachers (N = 75) were instructed to describe a standardized, video-recorded teaching situation in physics. The clustering approach was used to group related sentences. Results indicate that the pretrained language model-based clustering approach yields well-interpretable, specific, and robust clusters, which could be mapped to physics-specific and more general contents. Furthermore, the clusters facilitate advanced analysis of the textual organization of the constructed responses. Hence, we argue that machine learning and natural language processing provide science education researchers means to combine exploratory capabilities of qualitative research methods with the systematicity of quantitative methods.}, language = {en} } @article{LehmannKuhnKelleretal.2022, author = {Lehmann, Nico and Kuhn, Yves-Alain and Keller, Martin and Aye, Norman and Herold, Fabian and Draganski, Bogdan and Taube, Wolfgang and Taubert, Marco}, title = {Brain activation during active balancing and its behavioral relevance in younger and older adults}, series = {Frontiers in Aging Neuroscience}, volume = {14}, journal = {Frontiers in Aging Neuroscience}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {1663-4365}, doi = {10.3389/fnagi.2022.828474}, pages = {20}, year = {2022}, abstract = {Age-related deterioration of balance control is widely regarded as an important phenomenon influencing quality of life and longevity, such that a more comprehensive understanding of the neural mechanisms underlying this process is warranted. Specifically, previous studies have reported that older adults typically show higher neural activity during balancing as compared to younger counterparts, but the implications of this finding on balance performance remain largely unclear. Using functional near-infrared spectroscopy (fNIRS), differences in the cortical control of balance between healthy younger (n = 27) and older (n = 35) adults were explored. More specifically, the association between cortical functional activity and balance performance across and within age groups was investigated. To this end, we measured hemodynamic responses (i.e., changes in oxygenated and deoxygenated hemoglobin) while participants balanced on an unstable device. As criterion variables for brain-behavior-correlations, we also assessed postural sway while standing on a free-swinging platform and while balancing on wobble boards with different levels of difficulty. We found that older compared to younger participants had higher activity in prefrontal and lower activity in postcentral regions. Subsequent robust regression analyses revealed that lower prefrontal brain activity was related to improved balance performance across age groups, indicating that higher activity of the prefrontal cortex during balancing reflects neural inefficiency. We also present evidence supporting that age serves as a moderator in the relationship between brain activity and balance, i.e., cortical hemodynamics generally appears to be a more important predictor of balance performance in the older than in the younger. Strikingly, we found that age differences in balance performance are mediated by balancing-induced activation of the superior frontal gyrus, thus suggesting that differential activation of this region reflects a mechanism involved in the aging process of the neural control of balance. Our study suggests that differences in functional brain activity between age groups are not a mere by-product of aging, but instead of direct behavioral relevance for balance performance. Potential implications of these findings in terms of early detection of fall-prone individuals and intervention strategies targeting balance and healthy aging are discussed.}, language = {en} } @article{BaerBandara2022, author = {B{\"a}r, Christian and Bandara, Lashi}, title = {Boundary value problems for general first-order elliptic differential operators}, series = {Journal of functional analysis}, volume = {282}, journal = {Journal of functional analysis}, number = {12}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, issn = {0022-1236}, doi = {10.1016/j.jfa.2022.109445}, pages = {69}, year = {2022}, abstract = {We study boundary value problems for first-order elliptic differential operators on manifolds with compact boundary. The adapted boundary operator need not be selfadjoint and the boundary condition need not be pseudo-local.We show the equivalence of various characterisations of elliptic boundary conditions and demonstrate how the boundary conditions traditionally considered in the literature fit in our framework. The regularity of the solutions up to the boundary is proven. We show that imposing elliptic boundary conditions yields a Fredholm operator if the manifold is compact. We provide examples which are conveniently treated by our methods.}, language = {en} } @article{PolleyWernerBalderasValadezetal.2022, author = {Polley, Nabarun and Werner, Peter and Balderas-Valadez, Ruth Fabiola and Pacholski, Claudia}, title = {Bottom, top, or in between}, series = {Advanced materials interfaces}, volume = {9}, journal = {Advanced materials interfaces}, number = {15}, publisher = {Wiley}, address = {Hoboken}, issn = {2196-7350}, doi = {10.1002/admi.202102312}, pages = {10}, year = {2022}, abstract = {Attractive label-free plasmonic optical fiber sensors can be developed by cleverly choosing the arrangement of plasmonic nanostructures and other building blocks. Here, the final response depends very much on the alignment and position (stacking) of the individual elements. In this work, three different types of fiber optic sensing geometries fabricated by simple layer-by-layer stacking are presented, consisting of stimulus-sensitive poly-N-isopropylacrylamide (polyNIPAM) microgel arrays and plasmonic nanohole arrays (NHAs), namely NHA/polyNIPAM, polyNIPAM/NHA, polyNIPAM/NHA/polyNIPAM. Their optical response to a representative stimulus, namely temperature, is investigated. NHA/polyNIPAM monitors the volume phase transition of polyNIPAM microgels through changes in the spectral position and the amplitude of the reflection minimum of plasmonic NHA. In contrast, polyNIPAM/NHA shows a more complex response to the swelling and collapse of polyNIPAM microgels in their reflectance spectra. The most pronounced changes in optical response are observed by monitoring the amplitude of the reflectance minimum of this sensor during heating/cooling cycles. Finally, the triple stack of polyNIPAM/NHA/polyNIPAM at the end of a optical fiber tip combines the advantages of the NHA/polyNIPAM, polyNIPAM/NHA double stacks for optical sensing. The unique layer-by-layer stacking of microgel and nanostructure is customizable and can be easily adopted for other applications.}, language = {en} } @article{FloydSongHapeshietal.2022, author = {Floyd, Thomas G. and Song, Ji-Inn and Hapeshi, Alexia and Laroque, Sophie and Hartlieb, Matthias and Perrier, Sebastien}, title = {Bottlebrush copolymers for gene delivery: influence of architecture, charge density, and backbone length on transfection efficiency}, series = {Journal of materials chemistry : B, materials for biology and medicine}, volume = {10}, journal = {Journal of materials chemistry : B, materials for biology and medicine}, number = {19}, publisher = {Royal Society of Chemistry}, address = {London [u.a.]}, issn = {2050-750X}, doi = {10.1039/d2tb00490a}, pages = {3696 -- 3704}, year = {2022}, abstract = {The influence of polymer architecture of polycations on their ability to transfect mammalian cells is probed. Polymer bottle brushes with grafts made from partially hydrolysed poly(2-ethyl-2-oxazoline) are used while varying the length of the polymer backbone as well as the degree of hydrolysis (cationic charge content). Polyplex formation is investigated via gel electrophoresis, dye-displacement and dynamic light scattering. Bottle brushes show a superior ability to complex pDNA when compared to linear copolymers. Also, nucleic acid release was found to be improved by a graft architecture. Polyplexes based on bottle brush copolymers showed an elongated shape in transmission electron microscopy images. The cytotoxicity against mammalian cells is drastically reduced when a graft architecture is used instead of linear copolymers. Moreover, the best-performing bottle brush copolymer showed a transfection ability comparable with that of linear poly(ethylenimine), the gold standard of polymeric transfection agents, which is used as positive control. In combination with their markedly lowered cytotoxicity, cationic bottle brush copolymers are therefore shown to be a highly promising class of gene delivery vectors.}, language = {en} } @article{NagakuraSchubertWagneretal.2022, author = {Nagakura, Toshiki and Schubert, Florian and Wagner, Dirk and Kallmeyer, Jens}, title = {Biological sulfate reduction in deep subseafloor sediment of Guaymas Basin}, series = {Frontiers in microbiology}, volume = {13}, journal = {Frontiers in microbiology}, publisher = {Frontiers Media}, address = {Lausanne}, organization = {IODP Exp 385 Shipboard Sci Party}, issn = {1664-302X}, doi = {10.3389/fmicb.2022.845250}, pages = {12}, year = {2022}, abstract = {Sulfate reduction is the quantitatively most important process to degrade organic matter in anoxic marine sediment and has been studied intensively in a variety of settings. Guaymas Basin, a young marginal ocean basin, offers the unique opportunity to study sulfate reduction in an environment characterized by organic-rich sediment, high sedimentation rates, and high geothermal gradients (100-958 degrees C km(-1)). We measured sulfate reduction rates (SRR) in samples taken during the International Ocean Discovery Program (IODP) Expedition 385 using incubation experiments with radiolabeled (SO42-)-S-35 carried out at in situ pressure and temperature. The highest SRR (387 nmol cm(-3) d(-1)) was recorded in near-surface sediments from Site U1548C, which had the steepest geothermal gradient (958 degrees C km(-1)). At this site, SRR were generally over an order of magnitude higher than at similar depths at other sites (e.g., 387-157 nmol cm(-3) d(-1) at 1.9 mbsf from Site U1548C vs. 46-1.0 nmol cm(-3) d(-1) at 2.1 mbsf from Site U1552B). Site U1546D is characterized by a sill intrusion, but it had already reached thermal equilibrium and SRR were in the same range as nearby Site U1545C, which is minimally affected by sills. The wide temperature range observed at each drill site suggests major shifts in microbial community composition with very different temperature optima but awaits confirmation by molecular biological analyses. At the transition between the mesophilic and thermophilic range around 40 degrees C-60 degrees C, sulfate-reducing activity appears to be decreased, particularly in more oligotrophic settings, but shows a slight recovery at higher temperatures.}, language = {en} } @article{SchittkoOnandiaBernardVerdieretal.2022, author = {Schittko, Conrad and Onandia, Gabriela and Bernard-Verdier, Maud and Heger, Tina and Jeschke, Jonathan M. and Kowarik, Ingo and Maaß, Stefanie and Joshi, Jasmin}, title = {Biodiversity maintains soil multifunctionality and soil organic carbon in novel urban ecosystems}, series = {Journal of ecology}, volume = {110}, journal = {Journal of ecology}, number = {4}, publisher = {Wiley}, address = {Hoboken}, issn = {0022-0477}, doi = {10.1111/1365-2745.13852}, pages = {916 -- 934}, year = {2022}, abstract = {Biodiversity in urban ecosystems has the potential to increase ecosystem functions and support a suite of services valued by society, including services provided by soils. Specifically, the sequestration of carbon in soils has often been advocated as a solution to mitigate the steady increase in CO2 concentration in the atmosphere as a key driver of climate change. However, urban ecosystems are also characterized by an often high level of ecological novelty due to profound human-mediated changes, such as the presence of high numbers of non-native species, impervious surfaces or other disturbances. Yet it is poorly understood whether and how biodiversity affects ecosystem functioning and services of urban soils under these novel conditions. In this study, we assessed the influence of above- and below-ground diversity, as well as urbanization and plant invasions, on multifunctionality and organic carbon stocks of soils in non-manipulated grasslands along an urbanization gradient in Berlin, Germany. We focused on plant diversity (measured as species richness and functional trait diversity) and, in addition, on soil organism diversity as a potential mediator for the relationship of plant species diversity and ecosystem functioning. Our results showed positive effects of plant diversity on soil multifunctionality and soil organic carbon stocks along the entire gradient. Structural equation models revealed that plant diversity enhanced soil multifunctionality and soil organic carbon by increasing the diversity of below-ground organisms. These positive effects of plant diversity on soil multifunctionality and soil fauna were not restricted to native plant species only, but were also exerted by non-native species, although to a lesser degree. Synthesis. We conclude that enhancing diversity in plants and soil fauna of urban grasslands can increase the multifunctionality of urban soils and also add to their often underestimated but very valuable role in mitigating effects of climate change.}, language = {en} } @article{ZhangHuYangetal.2022, author = {Zhang, Kai and Hu, Jiege and Yang, Shuai and Xu, Wei and Wang, Zhichao and Zhuang, Peiwen and Grossart, Hans-Peter and Luo, Zhuhua}, title = {Biodegradation of polyester polyurethane by the marine fungus Cladosporium halotolerans 6UPA1}, series = {Journal of hazardous materials}, volume = {437}, journal = {Journal of hazardous materials}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0304-3894}, doi = {10.1016/j.jhazmat.2022.129406}, pages = {10}, year = {2022}, abstract = {Lack of degradability and the accumulation of polymeric wastes increase the risk for the health of the environment. Recently, recycling of polymeric waste materials becomes increasingly important as raw materials for polymer synthesis are in short supply due to the rise in price and supply chain disruptions. As an important polymer, polyurethane (PU) is widely used in modern life, therefore, PU biodegradation is desirable to avoid its accumulation in the environment. In this study, we isolated a fungal strain Cladosporium halotolerans from the deep sea which can grow in mineral medium with a polyester PU (Impranil DLN) as a sole carbon source. Further, we demonstrate that it can degrade up to 80\% of Impranil PU after 3 days of incubation at 28 celcius by breaking the carbonyl groups (1732 cm(-1)) and C-N-H bonds (1532 cm(-1) and 1247 cm(-1)) as confirmed by Fourier-transform infrared (FTIR) spectroscopy analysis. Gas chromatography-mass spectrometry (GC-MS) analysis revealed polyols and alkanes as PU degradation intermediates, indicating the hydrolysis of ester and urethane bonds. Esterase and urease activities were detected in 7 days-old cultures with PU as a carbon source. Transcriptome analysis showed a number of extracellular protein genes coding for enzymes such as cutinase, lipase, peroxidase and hydrophobic surface binding proteins A (HsbA) were expressed when cultivated on Impranil PU. The yeast two-hybrid assay revealed that the hydrophobic surface binding protein ChHsbA1 directly interacts with inducible esterases, ChLip1 (lipase) and ChCut1 (cutinase). Further, the KEGG pathway for "fatty acid degradation " was significantly enriched in Impranil PU inducible genes, indicating that the fungus may use the degradation intermediates to generate energy via this pathway. Taken together, our data indicates secretion of both esterase and hydrophobic surface binding proteins by C. halotolerans plays an important role in Impranil PU absorption and subsequent degradation. Our study provides a mechanistic insight into Impranil PU biodegradation by deep sea fungi and provides the basis for future development of biotechnological PU recycling.}, language = {en} } @article{SaidiZouhalBoullosaetal.2022, author = {Saidi, Karim and Zouhal, Hassane and Boullosa, Daniel and Dupont, Gregory and Hackney, Anthony C. and Bideau, Benoit and Granacher, Urs and Ben Abderrahman, Abderraouf}, title = {Biochemical markers and wellness status during a congested match play period in elite soccer players}, series = {International journal of sports physiology and performance : IJSSP}, volume = {17}, journal = {International journal of sports physiology and performance : IJSSP}, number = {4}, publisher = {Human Kinetics Publ.}, address = {Champaign}, issn = {1555-0265}, doi = {10.1123/ijspp.2020-0914}, pages = {605 -- 620}, year = {2022}, abstract = {Objectives: To analyze biochemical markers, wellness status, and physical fitness in elite soccer players in relation to changes in training and match exposure during a congested period of match play. Methods: Fourteen elite soccer players were evaluated 3 times (T1, T2, and T3) over 12 weeks (T1-T2: 6-wk regular period of match play and T2-T3: 6-wk congested period of match play). Players performed vertical jump tests, repeated shuttle sprint ability test, and the Yo-Yo Intermittent Recovery Test at T1, T2, and T3. Plasma C-reactive protein, creatinine, and creatine kinase were analyzed at T1, T2, and T3. Wellness status was measured daily using the Hopper questionnaire (delayed onset of muscle soreness, stress, fatigue, and sleep quality). Training session rating of perceived exertion was also recorded on a daily basis. Results: A significant increase was found in stress, fatigue, delayed onset of muscle soreness scores, and Hopper index during the congested period (between T2 and T3) compared with the regular period (between T1 and T2) (.001 < P < .008, 0.8 < ES < 2.3). Between T2 and T3, significant relationships were found between the percentage variations (Delta\%) of C-reactive protein, and Delta\% of creatine kinase with the Hopper Index, and the Delta\% of fatigue score. In addition, the Delta\% of fatigue score and Delta\% of delayed onset of muscle soreness score correlated with Delta\% Yo-Yo Intermittent Recovery Test and Delta\% best of repeated shuttle sprint ability test (.49 < r < P < .01). Conclusions: An intensive period of congested match play significantly compromised elite soccer players' physical fitness and wellness status. Elite soccer players' wellness status reflects declines in physical fitness during this period while biochemical changes do not.}, language = {en} } @article{FelserDrummer2022, author = {Felser, Claudia and Drummer, Janna-Deborah}, title = {Binding out of relative clauses in native and non-native sentence comprehension}, series = {Journal of psycholinguistic research}, volume = {51}, journal = {Journal of psycholinguistic research}, number = {4}, publisher = {Springer}, address = {New York}, issn = {0090-6905}, doi = {10.1007/s10936-022-09845-z}, pages = {763 -- 788}, year = {2022}, abstract = {Pronouns can sometimes covary with a non c-commanding quantifier phrase (QP). To obtain such 'telescoping' readings, a semantic representation must be computed in which the QP's semantic scope extends beyond its surface scope. Non-native speakers have been claimed to have more difficulty than native speakers deriving such non-isomorphic syntax-semantics mappings, but evidence from processing studies is scarce. We report the results from an eye-movement monitoring experiment and an offline questionnaire investigating whether native and non-native speakers of German can link personal pronouns to non c-commanding QPs inside relative clauses. Our results show that both participant groups were able to obtain telescoping readings offline, but only the native speakers showed evidence of forming telescoping dependencies during incremental parsing. During processing the non-native speakers focused on a discourse-prominent, non-quantified alternative antecedent instead. The observed group differences indicate that non-native comprehenders have more difficulty than native comprehenders computing scope-shifted representations in real time.}, language = {en} } @article{YangKimTuomainenetal.2022, author = {Yang, Jingdan and Kim, Jae-Hyun and Tuomainen, Outi and Rattanasone, Nan Xu}, title = {Bilingual Mandarin-English preschoolers' spoken narrative skills and contributing factors}, series = {Frontiers in Psyhology}, volume = {13}, journal = {Frontiers in Psyhology}, publisher = {Frontiers Media SA}, address = {Lausanne, Schweiz}, issn = {1664-1078}, doi = {10.3389/fpsyg.2022.797602}, pages = {12}, year = {2022}, abstract = {This study examined the spoken narrative skills of a group of bilingual Mandarin-English speaking 3-6-year-olds (N = 25) in Australia, using a remote online story-retell task. Bilingual preschoolers are an understudied population, especially those who are speaking typologically distinct languages such as Mandarin and English which have fewer structural overlaps compared to language pairs that are typologically closer, reducing cross-linguistic positive transfer. We examined these preschoolers' spoken narrative skills as measured by macrostructures (the global organization of a story) and microstructures (linguistic structures, e.g., total number of utterances, nouns, verbs, phrases, and modifiers) across and within each language, and how various factors such as age and language experiences contribute to individual variability. The results indicate that our bilingual preschoolers acquired spoken narrative skills similarly across their two languages, i.e., showing similar patterns of productivity for macrostructure and microstructure elements in both of their two languages. While chronological age was positively correlated with macrostructures in both languages (showing developmental effects), there were no significant correlations between measures of language experiences and the measures of spoken narrative skills (no effects for language input/output). The findings suggest that although these preschoolers acquire two typologically diverse languages in different learning environments, Mandarin at home with highly educated parents, and English at preschool, they displayed similar levels of oral narrative skills as far as these macro-/micro-structure measures are concerned. This study provides further evidence for the feasibility of remote online assessment of preschoolers' narrative skills.}, language = {en} } @article{NathanMonkArlinghausetal.2022, author = {Nathan, Ran and Monk, Christopher T. and Arlinghaus, Robert and Adam, Timo and Al{\´o}s, Josep and Assaf, Michael and Baktoft, Henrik and Beardsworth, Christine E. and Bertram, Michael G. and Bijleveld, Allert and Brodin, Tomas and Brooks, Jill L. and Campos-Candela, Andrea and Cooke, Steven J. and Gjelland, Karl O. and Gupte, Pratik R. and Harel, Roi and Hellstrom, Gustav and Jeltsch, Florian and Killen, Shaun S. and Klefoth, Thomas and Langrock, Roland and Lennox, Robert J. and Lourie, Emmanuel and Madden, Joah R. and Orchan, Yotam and Pauwels, Ine S. and Riha, Milan and R{\"o}leke, Manuel and Schl{\"a}gel, Ulrike and Shohami, David and Signer, Johannes and Toledo, Sivan and Vilk, Ohad and Westrelin, Samuel and Whiteside, Mark A. and Jaric, Ivan}, title = {Big-data approaches lead to an increased understanding of the ecology of animal movement}, series = {Science}, volume = {375}, journal = {Science}, number = {6582}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, issn = {0036-8075}, doi = {10.1126/science.abg1780}, pages = {734 -- +}, year = {2022}, abstract = {Understanding animal movement is essential to elucidate how animals interact, survive, and thrive in a changing world. Recent technological advances in data collection and management have transformed our understanding of animal "movement ecology" (the integrated study of organismal movement), creating a big-data discipline that benefits from rapid, cost-effective generation of large amounts of data on movements of animals in the wild. These high-throughput wildlife tracking systems now allow more thorough investigation of variation among individuals and species across space and time, the nature of biological interactions, and behavioral responses to the environment. Movement ecology is rapidly expanding scientific frontiers through large interdisciplinary and collaborative frameworks, providing improved opportunities for conservation and insights into the movements of wild animals, and their causes and consequences.}, language = {en} } @article{KrupnikWagnerVincentetal.2022, author = {Krupnik, Seweryn and Wagner, Aleksandra and Vincent, Olga and Rudek, Tadeusz J. and Wade, Robert and Misik, Mat{\´u}š and Akerboom, Sanne and Foulds, Chris and Smith Stegen, Karen and Adem, {\c{C}}iğdem and Batel, Susana and Rabitz, Florian and Certom{\`a}, Chiara and Chodkowska-Miszczuk, Justyna and Dokupilov{\´a}, Dušana and Leiren, Merethe D. and Ignatieva, Frolova M. and Gabald{\´o}n-Estevan, Daniel. and Horta, Ana and Karn{\o}e, Peter and Lilliestam, Johan and Loorbach, Derk A. and M{\"u}hlemeier, Susan and N{\´e}moz, Sophie and Nilsson, M{\aa}ns and Osička, Jan and Papamikrouli, Louiza and Pellizioni, Luigi and Sareen, Siddharth and Sarrica, Mauro and Seyfang, Gill and Sovacool, Benjamin K. and Telesiene, Audrone and Zapletalova, Veronika and von Wirth, Timo}, title = {Beyond technology}, series = {Energy research \& social science}, volume = {89}, journal = {Energy research \& social science}, publisher = {Elsevier}, address = {Amsterdam}, issn = {22146296}, doi = {10.1016/j.erss.2022.102536}, pages = {11}, year = {2022}, abstract = {This article enriches the existing literature on the importance and role of the social sciences and humanities (SSH) in renewable energy sources research by providing a novel approach to instigating the future research agenda in this field. Employing a series of in-depth interviews, deliberative focus group workshops and a systematic horizon scanning process, which utilised the expert knowledge of 85 researchers from the field with diverse disciplinary backgrounds and expertise, the paper develops a set of 100 priority questions for future research within SSH scholarship on renewable energy sources. These questions were aggregated into four main directions: (i) deep transformations and connections to the broader economic system (i.e. radical ways of (re)arranging socio-technical, political and economic relations), (ii) cultural and geographical diversity (i.e. contextual cultural, historical, political and socio-economic factors influencing citizen support for energy transitions), (iii) complexifying energy governance (i.e. understanding energy systems from a systems dynamics perspective) and (iv) shifting from instrumental acceptance to value-based objectives (i.e. public support for energy transitions as a normative notion linked to trust-building and citizen engagement). While this agenda is not intended to be—and cannot be—exhaustive or exclusive, we argue that it advances the understanding of SSH research on renewable energy sources and may have important value in the prioritisation of SSH themes needed to enrich dialogues between policymakers, funding institutions and researchers. SSH scholarship should not be treated as instrumental to other research on renewable energy but as intrinsic and of the same hierarchical importance.}, language = {en} } @article{AlmeidaRanisch2022, author = {Almeida, Mara and Ranisch, Robert}, title = {Beyond safety: mapping the ethical debate on heritable genome editing interventions}, series = {Humanities and Social Sciences Communications}, volume = {9}, journal = {Humanities and Social Sciences Communications}, number = {1}, publisher = {Springer Nature}, address = {London}, issn = {2662-9992}, doi = {10.1057/s41599-022-01147-y}, pages = {14}, year = {2022}, abstract = {Genetic engineering has provided humans the ability to transform organisms by direct manipulation of genomes within a broad range of applications including agriculture (e.g., GM crops), and the pharmaceutical industry (e.g., insulin production). Developments within the last 10 years have produced new tools for genome editing (e.g., CRISPR/Cas9) that can achieve much greater precision than previous forms of genetic engineering. Moreover, these tools could offer the potential for interventions on humans and for both clinical and non-clinical purposes, resulting in a broad scope of applicability. However, their promising abilities and potential uses (including their applicability in humans for either somatic or heritable genome editing interventions) greatly increase their potential societal impacts and, as such, have brought an urgency to ethical and regulatory discussions about the application of such technology in our society. In this article, we explore different arguments (pragmatic, sociopolitical and categorical) that have been made in support of or in opposition to the new technologies of genome editing and their impact on the debate of the permissibility or otherwise of human heritable genome editing interventions in the future. For this purpose, reference is made to discussions on genetic engineering that have taken place in the field of bioethics since the 1980s. Our analysis shows that the dominance of categorical arguments has been reversed in favour of pragmatic arguments such as safety concerns. However, when it comes to involving the public in ethical discourse, we consider it crucial widening the debate beyond such pragmatic considerations. In this article, we explore some of the key categorical as well sociopolitical considerations raised by the potential uses of heritable genome editing interventions, as these considerations underline many of the societal concerns and values crucial for public engagement. We also highlight how pragmatic considerations, despite their increasing importance in the work of recent authoritative sources, are unlikely to be the result of progress on outstanding categorical issues, but rather reflect the limited progress on these aspects and/or pressures in regulating the use of the technology.}, language = {en} } @article{AdairMcLaughlin2022, author = {Adair, Gigi and McLaughlin, Carly}, title = {Beyond humanitarianism}, series = {Narrating Flight and Asylum}, journal = {Narrating Flight and Asylum}, publisher = {Trier}, address = {WVT Wissenschaftlicher Verlag Trier}, isbn = {978-3-86821-965-4}, pages = {165 -- 182}, year = {2022}, language = {en} } @article{MarUngerWalderdorffetal.2022, author = {Mar, Kathleen A. and Unger, Charlotte and Walderdorff, Ludmila and Butler, Tim}, title = {Beyond CO2 equivalence}, series = {Environmental science \& policy}, volume = {134}, journal = {Environmental science \& policy}, publisher = {Elsevier}, address = {Oxford}, issn = {1462-9011}, doi = {10.1016/j.envsci.2022.03.027}, pages = {127 -- 136}, year = {2022}, abstract = {In this article we review the physical and chemical properties of methane (CH4) relevant to impacts on climate, ecosystems, and air pollution, and examine the extent to which this is reflected in climate and air pollution governance. Although CH4 is governed under the UNFCCC climate regime, its treatment there is limited to the ways in which it acts as a "CO2 equivalent" climate forcer on a 100-year time frame. The UNFCCC framework neglects the impacts that CH4 has on near-term climate, as well its impacts on human health and ecosystems, which are primarily mediated by methane's role as a precursor to tropospheric ozone. Frameworks for air quality governance generally address tropospheric ozone as a pollutant, but do not regulate CH4 itself. Methane's climate and air quality impacts, together with its alarming rise in atmospheric concentrations in recent years, make it clear that mitigation of CH4 emissions needs to be accelerated globally. We examine challenges and opportunities for further progress on CH4 mitigation within the international governance landscapes for climate change and air pollution.}, language = {en} } @article{VietzeSchwarzenthalMoffittetal.2022, author = {Vietze, Jana and Schwarzenthal, Miriam and Moffitt, Ursula and Civitillo, Sauro}, title = {Beyond 'migrant background': how to select relevant, social justice oriented, and feasible social categories in educational research}, series = {European journal of psychology of education}, volume = {38}, journal = {European journal of psychology of education}, number = {1}, publisher = {Springer}, address = {New York}, issn = {0256-2928}, doi = {10.1007/s10212-022-00611-2}, pages = {389 -- 408}, year = {2022}, abstract = {Across continental Europe, educational research samples are often divided by 'migrant background', a binary variable criticized for masking participant heterogeneity and reinforcing exclusionary norms of belonging. This study endorses more meaningful, representative, and precise research by offering four guiding questions for selecting relevant, social justice oriented, and feasible social categories for collecting and analysing data in psychological and educational research. Using a preregistered empirical example, we first compare selected social categories ('migrant background', family heritage, religion, citizenship, cultural identification, and generation status) in their potential to reveal participant heterogeneity. Second, we investigate differences in means and relations between variables (discrimination experiences, perceived societal Islamophobia, and national identity) and academic motivation among 1335 adolescents in Germany (48\% female, M-age = 14.69). Regression analyses and multigroup SEM revealed differential experiences with and implications of discrimination for academic motivation. Results highlight the need for a deliberate, transparent use of social categories to make discrimination visible and centre participants' subjective experiences.}, language = {en} } @article{MadaniAnghileriHeydenreichetal.2022, author = {Madani, Amiera and Anghileri, Lucia and Heydenreich, Matthias and M{\"o}ller, Heiko Michael and Pieber, Bartholom{\"a}us}, title = {Benzylic fluorination induced by a charge-transfer complex with a solvent-dependent selectivity switch}, series = {Organic letters / publ. by the American Chemical Society}, volume = {24}, journal = {Organic letters / publ. by the American Chemical Society}, number = {29}, publisher = {American Chemical Society}, address = {Washington}, issn = {1523-7060}, doi = {10.1021/acs.orglett.2c02050}, pages = {5376 -- 5380}, year = {2022}, abstract = {We present a divergent strategy for the fluorination of phenylacetic acid derivatives that is induced by a charge-transfer complex between Selectfluor and 4-(dimethylamino)pyridine. A comprehensive investigation of the conditions revealed a critical role of the solvent on the reaction outcome. In the presence of water, decarboxylative fluorination through a single-electron oxidation is dominant. Non-aqueous conditions result in the clean formation of alpha-fluoro-alpha-arylcarboxylic acids.}, language = {en} } @article{GerickeSoemerSchiefele2022, author = {Gericke, Christian and Soemer, Alexander and Schiefele, Ulrich}, title = {Benefits of Mind Wandering for Learning in School Through Its Positive Effects on Creativity}, series = {Frontiers in Education}, volume = {7}, journal = {Frontiers in Education}, publisher = {Frontiers Media SA}, address = {Lausanne, Schweiz}, issn = {2504-284X}, doi = {10.3389/feduc.2022.774731}, pages = {11}, year = {2022}, abstract = {There is broad agreement among researchers to view mind wandering as an obstacle to learning because it draws attention away from learning tasks. Accordingly, empirical findings revealed negative correlations between the frequency of mind wandering during learning and various kinds of learning outcomes (e.g., text retention). However, a few studies have indicated positive effects of mind wandering on creativity in real-world learning environments. The present article reviews these studies and highlights potential benefits of mind wandering for learning mediated through creative processes. Furthermore, we propose various ways to promote useful mind wandering and, at the same time, minimize its negative impact on learning.}, language = {en} } @article{EscalanteDominguezGomezRuizetal.2022, author = {Escalante, Ignacio and Dominguez, Marisol and Gomez-Ruiz, Daisy Alejandra and Machado, Glauco}, title = {Benefits and costs of mixed-species aggregations in Harvestmen (Arachnida: Opiliones)}, series = {Frontiers in ecology and evolution}, volume = {9}, journal = {Frontiers in ecology and evolution}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-701X}, doi = {10.3389/fevo.2021.766323}, pages = {24}, year = {2022}, abstract = {Many animals form aggregations with individuals of the same species (single-species aggregations, SSA). Less frequently, individuals may also aggregate with individuals of other species (mixed-species aggregations, MSA). Although the benefits and costs of SSA have been intensively studied, the same is not true for MSA. Here, we first review the cases of MSA in harvestmen, an arachnid order in which the records of MSA are more frequent than other arthropod orders. We then propose several benefits and costs of MSA in harvestmen, and contrast them with those of SSA. Second, using field-gathered data we describe gregariousness in seven species of Prionostemma harvestmen from Costa Rica. These species form MSA, but individuals are also found solitarily or in SSA. We tested one possible benefit and one possible cost of gregariousness in Prionostemma harvestmen. Regarding the benefit, we hypothesized that individuals missing legs would be more exposed to predation than eight-legged individuals and thus they should be found preferentially in aggregations, where they would be more protected from predators. Our data, however, do not support this hypothesis. Regarding the cost, we hypothesized that gregariousness increases the chances of parasitism. We found no support for this hypothesis either because both mite prevalence and infestation intensity did not differ between solitary or aggregated individuals. Additionally, the type of aggregation (SSA or MSA) was not associated with the benefit or the cost we explored. This lack of effect may be explained by the fluid membership of the aggregations, as we found high turnover over time in the number of individuals and species composition of the aggregations. In conclusion, we hope our review and empirical data stimulate further studies on MSA, which remains one of the most elusive forms of group living in animals.}, language = {en} } @article{Bruno2022, author = {Bruno, Daniele}, title = {Being fully excused for wrongdoing}, series = {Pacific philosophical quarterly}, volume = {104}, journal = {Pacific philosophical quarterly}, number = {2}, publisher = {Wiley-Blackwell}, address = {Hoboken, NJ}, issn = {0279-0750}, doi = {10.1111/papq.12425}, pages = {324 -- 347}, year = {2022}, abstract = {On the classical understanding, an agent is fully excused for an action if and only if performing this action was a case of faultless wrongdoing. A major motivation for this view is the apparent existence of paradigmatic types of excusing considerations, affecting fault but not wrongness. I show that three such considerations, ignorance, duress and compulsion, can be shown to have direct bearing on the permissibility of actions. The appeal to distinctly identifiable excusing considerations thus does not stand up to closer scrutiny, undermining the classical view and giving us reason to seek alternative ways of drawing the justification/excuse distinction.}, language = {en} } @article{ParrySchlaegelTiedemannetal.2022, author = {Parry, Victor and Schl{\"a}gel, Ulrike E. and Tiedemann, Ralph and Weithoff, Guntram}, title = {Behavioural Responses of Defended and Undefended Prey to Their Predator}, series = {Biology}, volume = {11}, journal = {Biology}, number = {8}, publisher = {MDPI}, address = {Basel, Schweiz}, issn = {2079-7737}, doi = {10.3390/biology11081217}, pages = {14}, year = {2022}, abstract = {Predation is a strong species interaction causing severe harm or death to prey. Thus, prey species have evolved various defence strategies to minimize predation risk, which may be immediate (e.g., a change in behaviour) or transgenerational (morphological defence structures). We studied the behaviour of two strains of a rotiferan prey (Brachionus calyciflorus) that differ in their ability to develop morphological defences in response to their predator Asplanchna brightwellii. Using video analysis, we tested: (a) if two strains differ in their response to predator presence and predator cues when both are undefended; (b) whether defended individuals respond to live predators or their cues; and (c) if the morphological defence (large spines) per se has an effect on the swimming behaviour. We found a clear increase in swimming speed for both undefended strains in predator presence. However, the defended specimens responded neither to the predator presence nor to their cues, showing that they behave indifferently to their predator when they are defended. We did not detect an effect of the spines on the swimming behaviour. Our study demonstrates a complex plastic behaviour of the prey, not only in the presence of their predator, but also with respect to their defence status.}, language = {en} } @article{ParrySchlaegelTiedemannetal.2022, author = {Parry, Victor and Schl{\"a}gel, Ulrike E. and Tiedemann, Ralph and Weithoff, Guntram}, title = {Behavioural responses of defended and undefended prey to their predator}, series = {Biology : open access journal}, volume = {11}, journal = {Biology : open access journal}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {2079-7737}, doi = {10.3390/biology11081217}, pages = {14}, year = {2022}, abstract = {Many animals that have to cope with predation have evolved mechanisms to reduce their predation risk. One of these mechanisms is change in morphology, for example, the development of spines. These spines are induced, when mothers receive chemical signals of a predator (kairomones) and their daughters are then equipped with defensive spines. We studied the behaviour of a prey and its predator when the prey is either defended or undefended. We used common aquatic micro-invertebrates, the rotifers Brachionus calyciflorus (prey) and Asplanchna brightwellii (predator) as experimental animals. We found that undefended prey increased its swimming speed in the presence of the predator. The striking result was that the defended prey did not respond to the predator's presence. This suggests that defended prey has a different response behaviour to a predator than undefended conspecifics. Our study provides further insights into complex zooplankton predator-prey interactions. Predation is a strong species interaction causing severe harm or death to prey. Thus, prey species have evolved various defence strategies to minimize predation risk, which may be immediate (e.g., a change in behaviour) or transgenerational (morphological defence structures). We studied the behaviour of two strains of a rotiferan prey (Brachionus calyciflorus) that differ in their ability to develop morphological defences in response to their predator Asplanchna brightwellii. Using video analysis, we tested: (a) if two strains differ in their response to predator presence and predator cues when both are undefended; (b) whether defended individuals respond to live predators or their cues; and (c) if the morphological defence (large spines) per se has an effect on the swimming behaviour. We found a clear increase in swimming speed for both undefended strains in predator presence. However, the defended specimens responded neither to the predator presence nor to their cues, showing that they behave indifferently to their predator when they are defended. We did not detect an effect of the spines on the swimming behaviour. Our study demonstrates a complex plastic behaviour of the prey, not only in the presence of their predator, but also with respect to their defence status.}, language = {en} } @article{FuhrmeisterMadecLorenzetal.2022, author = {Fuhrmeister, Pamela and Madec, Sylvain and Lorenz, Antje and Elbuy, Shereen and B{\"u}rki Foschini, Audrey Damaris}, title = {Behavioural and EEG evidence for inter-individual variability in late encoding stages of word production}, series = {Language, cognition and neuroscience}, volume = {37}, journal = {Language, cognition and neuroscience}, number = {7}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {2327-3798}, doi = {10.1080/23273798.2022.2030483}, pages = {902 -- 924}, year = {2022}, abstract = {Individuals differ in the time needed to name a picture. This contribution asks whether this inter-individual variability emerges in earlier stages of word production (e.g. lexical selection) or later stages (e.g. articulation) and examines the consequences of this variability for EEG group results. We measured participants' (N = 45) naming latencies and continuous EEG in a picture-word interference task and naming latencies in a delayed naming task. Inter-individual variability in naming latencies in immediate naming (in contrast with inter-item variability) was not larger than the variability in the delayed task, suggesting that some variability in immediate naming originates in later stages of word production. EEG data complemented this interpretation: Differences between relatively fast vs. slow speakers emerged in response-aligned analyses in a time window close to the vocal response. We additionally present a method to assess the generalisability of the timing of effects across participants based on random sampling.}, language = {en} } @article{daSilvaCostaHortobagyidenOtteretal.2022, author = {da Silva Costa, Andreia Abud and Hortobagyi, Tibor and den Otter, Rob and Sawers, Andrew and Moraes, Renato}, title = {Beam width and arm position but not cognitive task affect walking balance in older adults}, series = {Scientific reports}, volume = {12}, journal = {Scientific reports}, number = {1}, publisher = {Nature Research}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-022-10848-y}, pages = {10}, year = {2022}, abstract = {Detection of changes in dynamic balance could help identify older adults at fall risk. Walking on a narrow beam with its width, cognitive load, and arm position manipulated could be an alternative to current tests. Therefore, we examined additive and interactive effects of beam width, cognitive task (CT), and arm position on dynamic balance during beam walking in older adults. Twenty older adults (69 +/- 4y) walked on 6, 8, and 10-cm wide beams (2-cm high, 4-m-long), with and without CT, with three arm positions (free, crossed, akimbo). We determined cognitive errors, distance walked, step speed, root mean square (RMS) of center of mass (COM) displacement and trunk acceleration in the frontal plane. Beam width decrease progressively reduced distance walked and increased trunk acceleration RMS. Step speed decreased on the narrowest beam and with CT. Arm crossing decreased distance walked and step speed. COM displacement RMS and cognitive errors were not affected by any manipulation. In conclusion, distance walked indicated that beam width and arm position, but less so CT, affected dynamic balance, implying that beam walking has the potential to become a test of fall risk. Stability measurements suggested effective trunk adjustments to control COM position and keep dynamic balance during the task.}, language = {en} } @article{ThapaParkKimetal.2022, author = {Thapa, Samudrajit and Park, Seongyu and Kim, Yeongjin and Jeon, Jae-Hyung and Metzler, Ralf and Lomholt, Michael A.}, title = {Bayesian inference of scaled versus fractional Brownian motion}, series = {Journal of physics : A, mathematical and theoretical}, volume = {55}, journal = {Journal of physics : A, mathematical and theoretical}, number = {19}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1751-8113}, doi = {10.1088/1751-8121/ac60e7}, pages = {21}, year = {2022}, abstract = {We present a Bayesian inference scheme for scaled Brownian motion, and investigate its performance on synthetic data for parameter estimation and model selection in a combined inference with fractional Brownian motion. We include the possibility of measurement noise in both models. We find that for trajectories of a few hundred time points the procedure is able to resolve well the true model and parameters. Using the prior of the synthetic data generation process also for the inference, the approach is optimal based on decision theory. We include a comparison with inference using a prior different from the data generating one.}, language = {en} } @article{BernerTrauthHolschneider2022, author = {Berner, Nadine and Trauth, Martin H. and Holschneider, Matthias}, title = {Bayesian inference about Plio-Pleistocene climate transitions in Africa}, series = {Quaternary science reviews : the international multidisciplinary research and review journal}, volume = {277}, journal = {Quaternary science reviews : the international multidisciplinary research and review journal}, publisher = {Elsevier}, address = {Oxford}, issn = {0277-3791}, doi = {10.1016/j.quascirev.2021.107287}, pages = {12}, year = {2022}, abstract = {During the last 5 Ma the Earth's ocean-atmosphere system passed through several major transitions, many of which are discussed as possible triggers for human evolution. A classic in this context is the possible influence of the closure of the Panama Strait, the intensification of Northern Hemisphere Glaciation, a stepwise increase in aridity in Africa, and the first appearance of the genus Homo about 2.5 - 2.7 Ma ago. Apart from the fact that the correlation between these events does not necessarily imply causality, many attempts to establish a relationship between climate and evolution fail due to the challenge of precisely localizing an a priori unknown number of changes potentially underlying complex climate records. The kernel-based Bayesian inference approach applied here allows inferring the location, generic shape, and temporal scale of multiple transitions in established records of Plio-Pleistocene African climate. By defining a transparent probabilistic analysis strategy, we are able to identify conjoint changes occurring across the investigated terrigenous dust records from Ocean Drilling Programme (ODP) sites in the Atlantic Ocean (ODP 659), Arabian (ODP 721/722) and Mediterranean Sea (ODP 967). The study indicates a two-step transition in the African climate proxy records at (2.35-2.10) Ma and (1.70 - 1.50) Ma, that may be associated with the reorganization of the Hadley-Walker Circulation. .}, language = {en} } @article{SecklerMetzler2022, author = {Seckler, Henrik and Metzler, Ralf}, title = {Bayesian deep learning for error estimation in the analysis of anomalous diffusion}, series = {Nature Communnications}, volume = {13}, journal = {Nature Communnications}, publisher = {Nature Publishing Group UK}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-022-34305-6}, pages = {13}, year = {2022}, abstract = {Modern single-particle-tracking techniques produce extensive time-series of diffusive motion in a wide variety of systems, from single-molecule motion in living-cells to movement ecology. The quest is to decipher the physical mechanisms encoded in the data and thus to better understand the probed systems. We here augment recently proposed machine-learning techniques for decoding anomalous-diffusion data to include an uncertainty estimate in addition to the predicted output. To avoid the Black-Box-Problem a Bayesian-Deep-Learning technique named Stochastic-Weight-Averaging-Gaussian is used to train models for both the classification of the diffusionmodel and the regression of the anomalous diffusion exponent of single-particle-trajectories. Evaluating their performance, we find that these models can achieve a wellcalibrated error estimate while maintaining high prediction accuracies. In the analysis of the output uncertainty predictions we relate these to properties of the underlying diffusion models, thus providing insights into the learning process of the machine and the relevance of the output.}, language = {en} } @article{SecklerMetzler2022, author = {Seckler, Henrik and Metzler, Ralf}, title = {Bayesian deep learning for error estimation in the analysis of anomalous diffusion}, series = {Nature Communications}, volume = {13}, journal = {Nature Communications}, number = {1}, publisher = {Nature portfolio}, address = {Berlin}, issn = {2041-1723}, doi = {10.1038/s41467-022-34305-6}, pages = {13}, year = {2022}, abstract = {Modern single-particle-tracking techniques produce extensive time-series of diffusive motion in a wide variety of systems, from single-molecule motion in living-cells to movement ecology. The quest is to decipher the physical mechanisms encoded in the data and thus to better understand the probed systems. We here augment recently proposed machine-learning techniques for decoding anomalous-diffusion data to include an uncertainty estimate in addition to the predicted output. To avoid the Black-Box-Problem a Bayesian-Deep-Learning technique named Stochastic-Weight-Averaging-Gaussian is used to train models for both the classification of the diffusion model and the regression of the anomalous diffusion exponent of single-particle-trajectories. Evaluating their performance, we find that these models can achieve a well-calibrated error estimate while maintaining high prediction accuracies. In the analysis of the output uncertainty predictions we relate these to properties of the underlying diffusion models, thus providing insights into the learning process of the machine and the relevance of the output.
Diffusive motions in complex environments such as living biological cells or soft matter systems can be analyzed with single-particle-tracking approaches, where accuracy of output may vary. The authors involve a machine-learning technique for decoding anomalous-diffusion data and provide an uncertainty estimate together with predicted output.}, language = {en} } @article{PietrekKangasKliegletal.2022, author = {Pietrek, Anou F. and Kangas, Maria and Kliegl, Reinhold and Rapp, Michael A. and Heinzel, Stephan and Van der Kaap-Deeder, Jolene and Heissel, Andreas}, title = {Basic psychological need satisfaction and frustration in major depressive disorder}, series = {Frontiers in Psychiatry - Mood Disorders}, journal = {Frontiers in Psychiatry - Mood Disorders}, publisher = {Frontiers Media S.A.}, address = {Lausanne, Schweiz}, issn = {1664-0640}, doi = {10.3389/fpsyt.2022.962501}, pages = {1 -- 10}, year = {2022}, abstract = {Basic psychological needs theory postulates that a social environment that satisfies individuals' three basic psychological needs of autonomy, competence, and relatedness leads to optimal growth and well-being. On the other hand, the frustration of these needs is associated with ill-being and depressive symptoms foremost investigated in non-clinical samples; yet, there is a paucity of research on need frustration in clinical samples. Survey data were compared between adult individuals with major depressive disorder (MDD; n = 115; 48.69\% female; 38.46 years, SD = 10.46) with those of a non-depressed comparison sample (n = 201; 53.23\% female; 30.16 years, SD = 12.81). Need profiles were examined with a linear mixed model (LMM). Individuals with depression reported higher levels of frustration and lower levels of satisfaction in relation to the three basic psychological needs when compared to non-depressed adults. The difference between depressed and non-depressed groups was significantly larger for frustration than satisfaction regarding the needs for relatedness and competence. LMM correlation parameters confirmed the expected positive correlation between the three needs. This is the first study showing substantial differences in need-based experiences between depressed and non-depressed adults. The results confirm basic assumptions of the self-determination theory and have preliminary implications in tailoring therapy for depression.}, language = {en} } @article{IlicicGrossart2022, author = {Ilicic, Doris and Grossart, Hans-Peter}, title = {Basal parasitic fungi in marine food webs-a mystery yet to unravel}, series = {Journal of Fungi}, volume = {8}, journal = {Journal of Fungi}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2309-608X}, doi = {10.3390/jof8020114}, pages = {16}, year = {2022}, abstract = {Although aquatic and parasitic fungi have been well known for more than 100 years, they have only recently received increased awareness due to their key roles in microbial food webs and biogeochemical cycles. There is growing evidence indicating that fungi inhabit a wide range of marine habitats, from the deep sea all the way to surface waters, and recent advances in molecular tools, in particular metagenome approaches, reveal that their diversity is much greater and their ecological roles more important than previously considered. Parasitism constitutes one of the most widespread ecological interactions in nature, occurring in almost all environments. Despite that, the diversity of fungal parasites, their ecological functions, and, in particular their interactions with other microorganisms remain largely speculative, unexplored and are often missing from current theoretical concepts in marine ecology and biogeochemistry. In this review, we summarize and discuss recent research avenues on parasitic fungi and their ecological potential in marine ecosystems, e.g., the fungal shunt, and emphasize the need for further research.}, language = {en} } @article{EsmaeilishirazifardUsherTrimetal.2022, author = {Esmaeilishirazifard, Elham and Usher, Louise and Trim, Carol and Denise, Hubert and Sangal, Vartul and Tyson, Gregory H. and Barlow, Axel and Redway, Keith F. and Taylor, John D. and Kremyda-Vlachou, Myrto and Davies, Sam and Loftus, Teresa D. and Lock, Mikaella M. G. and Wright, Kstir and Dalby, Andrew and Snyder, Lori A. S. and Wuster, Wolfgang and Trim, Steve and Moschos, Sterghios A.}, title = {Bacterial adaptation to venom in snakes and arachnida}, series = {Microbiology spectrum}, volume = {10}, journal = {Microbiology spectrum}, number = {3}, publisher = {American Society for Microbiology}, address = {Birmingham, Ala.}, issn = {2165-0497}, doi = {10.1128/spectrum.02408-21}, pages = {16}, year = {2022}, abstract = {Notwithstanding their 3 to 5\% mortality, the 2.7 million envenomation-related injuries occurring annually-predominantly across Africa, Asia, and Latin America-are also major causes of morbidity. Venom toxin-damaged tissue will develop infections in some 75\% of envenomation victims, with E. faecalis being a common culprit of disease; however, such infections are generally considered to be independent of envenomation. Animal venoms are considered sterile sources of antimicrobial compounds with strong membrane-disrupting activity against multidrug-resistant bacteria. However, venomous bite wound infections are common in developing nations. Investigating the envenomation organ and venom microbiota of five snake and two spider species, we observed venom community structures that depend on the host venomous animal species and evidenced recovery of viable microorganisms from black-necked spitting cobra (Naja nigricollis) and Indian ornamental tarantula (Poecilotheria regalis) venoms. Among the bacterial isolates recovered from N. nigricollis, we identified two venom-resistant, novel sequence types of Enterococcus faecalis whose genomes feature 16 virulence genes, indicating infectious potential, and 45 additional genes, nearly half of which improve bacterial membrane integrity. Our findings challenge the dogma of venom sterility and indicate an increased primary infection risk in the clinical management of venomous animal bite wounds. IMPORTANCE Notwithstanding their 3 to 5\% mortality, the 2.7 million envenomation-related injuries occurring annually-predominantly across Africa, Asia, and Latin America-are also major causes of morbidity. Venom toxin-damaged tissue will develop infections in some 75\% of envenomation victims, with E. faecalis being a common culprit of disease; however, such infections are generally considered to be independent of envenomation. Here, we provide evidence on venom microbiota across snakes and arachnida and report on the convergent evolution mechanisms that can facilitate adaptation to black-necked cobra venom in two independent E. faecalis strains, easily misidentified by biochemical diagnostics. Therefore, since inoculation with viable and virulence gene-harboring bacteria can occur during envenomation, acute infection risk management following envenomation is warranted, particularly for immunocompromised and malnourished victims in resource-limited settings. These results shed light on how bacteria evolve for survival in one of the most extreme environments on Earth and how venomous bites must be also treated for infections.}, language = {en} } @article{DaempflingMielkeKoellneretal.2022, author = {D{\"a}mpfling, Helge L. C. and Mielke, Christian and Koellner, Nicole and Lorenz, Melanie and Rogass, Christian and Altenberger, Uwe and Harlov, Daniel E. and Knoper, Michael}, title = {Automatic element and mineral detection in thin sections using hyperspectral transmittance imaging microscopy (HyperTIM)}, series = {European journal of mineralogy}, volume = {34}, journal = {European journal of mineralogy}, number = {3}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {0935-1221}, doi = {10.5194/ejm-34-275-2022}, pages = {275 -- 284}, year = {2022}, abstract = {In this study we present a novel method for the automatic detection of minerals and elements using hyperspectral transmittance imaging microscopy measurements of complete thin sections (HyperTIM). This is accomplished by using a hyperspectral camera system that operates in the visible and near-infrared (VNIR) range with a specifically designed sample holder, scanning setup, and a microscope lens. We utilize this method on a monazite ore thin section from Steenkampskraal (South Africa), which we analyzed for the rare earth element (REE)-bearing mineral monazite ((Ce,Nd,La)PO4), with high concentrations of Nd. The transmittance analyses with the hyperspectral VNIR camera can be used to identify REE minerals and Nd in thin sections. We propose a three-point band depth index, the Nd feature depth index (NdFD), and its related product the Nd band depth index (NdBDI), which enables automatic mineral detection and classification for the Nd-bearing monazites in thin sections. In combination with the average concentration of the relative Nd content, it permits a destruction-free, total concentration calculation for Nd across the entire thin section.}, language = {en} } @article{StojkoskiSandevKocarevetal.2022, author = {Stojkoski, Viktor and Sandev, Trifce and Kocarev, Ljupco and Pal, Arnab}, title = {Autocorrelation functions and ergodicity in diffusion with stochastic resetting}, series = {Journal of physics : A, Mathematical and theoretical}, volume = {55}, journal = {Journal of physics : A, Mathematical and theoretical}, number = {10}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1751-8113}, doi = {10.1088/1751-8121/ac4ce9}, pages = {22}, year = {2022}, abstract = {Diffusion with stochastic resetting is a paradigm of resetting processes. Standard renewal or master equation approach are typically used to study steady state and other transport properties such as average, mean squared displacement etc. What remains less explored is the two time point correlation functions whose evaluation is often daunting since it requires the implementation of the exact time dependent probability density functions of the resetting processes which are unknown for most of the problems. We adopt a different approach that allows us to write a stochastic solution for a single trajectory undergoing resetting. Moments and the autocorrelation functions between any two times along the trajectory can then be computed directly using the laws of total expectation. Estimation of autocorrelation functions turns out to be pivotal for investigating the ergodic properties of various observables for this canonical model. In particular, we investigate two observables (i) sample mean which is widely used in economics and (ii) time-averaged-mean-squared-displacement (TAMSD) which is of acute interest in physics. We find that both diffusion and drift-diffusion processes with resetting are ergodic at the mean level unlike their reset-free counterparts. In contrast, resetting renders ergodicity breaking in the TAMSD while both the stochastic processes are ergodic when resetting is absent. We quantify these behaviors with detailed analytical study and corroborate with extensive numerical simulations. Our results can be verified in experimental set-ups that can track single particle trajectories and thus have strong implications in understanding the physics of resetting.}, language = {en} } @article{PuppeLeueSommeretal.2022, author = {Puppe, Daniel and Leue, Martin and Sommer, Michael and Schaller, J{\"o}rg and Kaczorek, Danuta}, title = {Auto-fluorescence in phytoliths}, series = {Frontiers in Environmental Science}, volume = {10}, journal = {Frontiers in Environmental Science}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-665X}, doi = {10.3389/fenvs.2022.915947}, pages = {14}, year = {2022}, abstract = {The detection of auto-fluorescence in phytogenic, hydrated amorphous silica depositions (phytoliths) has been found to be a promising approach to verify if phytoliths were burnt or not, especially in archaeological contexts. However, it is unknown so far at what temperature and how auto-fluorescence is induced in phytoliths. We used fluorescence microscopy, scanning electron microscope-energy dispersive X-ray spectroscopy (SEM-EDX), and Fourier transform infrared spectroscopy to analyze auto-fluorescence in modern phytoliths extracted from plant samples or in intact leaves of winter wheat. Leaves and extracted phytoliths were heated at different temperatures up to 600 degrees C. The aims of our experiments were i) to find out what temperature is needed to induce auto-fluorescence in phytoliths, ii) to detect temperature-dependent changes in the molecular structure of phytoliths related to auto-fluorescence, and iii) to derive a mechanistic understanding of auto-fluorescence in phytoliths. We found organic compounds associated with phytoliths to cause auto-fluorescence in phytoliths treated at temperatures below approx. 400 degrees C. In phytoliths treated at higher temperatures, i.e., 450 and 600 degrees C, phytolith auto-fluorescence was mainly caused by molecular changes of phytolith silica. Based on our results we propose that auto-fluorescence in phytoliths is caused by clusterization-triggered emissions, which are caused by overlapping electron clouds forming non-conventional chromophores. In phytoliths heated at temperatures above about 400 degrees C dihydroxylation and the formation of siloxanes result in oxygen clusters that serve as non-conventional chromophores in fluorescence events. Furthermore, SEM-EDX analyses revealed that extractable phytoliths were dominated by lumen phytoliths (62\%) compared to cell wall phytoliths (38\%). Our findings might be not only relevant in archaeological phytolith-based examinations, but also for studies on the temperature-dependent release of silicon from phytoliths and the potential of long-term carbon sequestration in phytoliths.}, language = {en} } @article{JohanssonLeitnerBidermaneetal.2022, author = {Johansson, Fredrik O. L. and Leitner, Torsten and Bidermane, Ieva and Born, Artur and F{\"o}hlisch, Alexander and Svensson, Svante and M{\aa}rtensson, Nils and Lindblad, Andreas}, title = {Auger- and photoelectron coincidences of molecular O2 adsorbed on Ag(111)}, series = {Journal of electron spectroscopy and related phenomena : the international journal on theoretical and experimental aspects of electron spectroscopy}, volume = {256}, journal = {Journal of electron spectroscopy and related phenomena : the international journal on theoretical and experimental aspects of electron spectroscopy}, publisher = {Elsevier}, address = {New York, NY [u.a.]}, issn = {0368-2048}, doi = {10.1016/j.elspec.2022.147174}, pages = {6}, year = {2022}, abstract = {The oxygen on Ag(111) system has been investigated with Auger electron-photoelectron coincidence spectroscopy (APECS). The coincidence spectra between O 1s core level photoelectrons and O KLL Auger electrons have been studied together with Ag(3)d/AgM4,5NN coincidences. We also describe the electron-electron coincidence spectrometer setup, CoESCA, consisting of two angle resolved time-of-flight spectrometers at a synchrotron light source. Contributions from molecular oxygen and chemisorbed oxygen are assigned using the coincidence data, conclusions are drawn primarily from the O 1s/O KLL data. The data acquisition and treatment procedure are also outlined. The chemisorbed oxygen species observed are relevant for the catalytic ethylene oxidation.}, language = {en} } @article{GerlachPreitschopfKaraevetal.2022, author = {Gerlach, Marius and Preitschopf, Tobias and Karaev, Emil and Quitian-Lara, Heidy Mayerly and Mayer, Dennis and Bozek, John and Fischer, Ingo and Fink, Reinhold F.}, title = {Auger electron spectroscopy of fulminic acid, HCNO}, series = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, volume = {24}, journal = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, number = {25}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/d2cp02104h}, pages = {15217 -- 15229}, year = {2022}, abstract = {HCNO is a molecule of considerable astrochemical interest as a precursor to prebiotic molecules. It is synthesized by preparative pyrolysis and is unstable at room temperature. Here, we investigate its spectroscopy in the soft X-ray regime at the C 1s, N 1s and O 1s edges. All 1s ionization energies are reported and X-ray absorption spectra reveal the transitions from the 1s to the pi* state. Resonant and normal Auger electron spectra for the decay of the core hole states are recorded in a hemispherical analyzer. An assignment of the experimental spectra is provided with the aid of theoretical counterparts. The latter are using a valence configuration interaction representation of the intermediate and final state energies and wavefunctions, the one-center approximation for transition rates and band shapes according to the moment theory. The computed spectra are in very good agreement with the experimental data and most of the relevant bands are assigned. Additionally, we present a simple approach to estimate relative Auger transition rates on the basis of a minimal basis representation of the molecular orbitals. We demonstrate that this provides a qualitatively good and reliable estimate for several signals in the normal and resonant Auger electron spectra which have significantly different intensities in the decay of the three core holes.}, language = {en} } @article{PadashSandevKantzetal.2022, author = {Padash, Amin and Sandev, Trifce and Kantz, Holger and Metzler, Ralf and Chechkin, Aleksei}, title = {Asymmetric Levy flights are more efficient in random search}, series = {Fractal and fractional}, volume = {6}, journal = {Fractal and fractional}, number = {5}, publisher = {MDPI}, address = {Basel}, issn = {2504-3110}, doi = {10.3390/fractalfract6050260}, pages = {23}, year = {2022}, abstract = {We study the first-arrival (first-hitting) dynamics and efficiency of a one-dimensional random search model performing asymmetric Levy flights by leveraging the Fokker-Planck equation with a delta-sink and an asymmetric space-fractional derivative operator with stable index alpha and asymmetry (skewness) parameter beta. We find exact analytical results for the probability density of first-arrival times and the search efficiency, and we analyse their behaviour within the limits of short and long times. We find that when the starting point of the searcher is to the right of the target, random search by Brownian motion is more efficient than Levy flights with beta <= 0 (with a rightward bias) for short initial distances, while for beta>0 (with a leftward bias) Levy flights with alpha -> 1 are more efficient. When increasing the initial distance of the searcher to the target, Levy flight search (except for alpha=1 with beta=0) is more efficient than the Brownian search. Moreover, the asymmetry in jumps leads to essentially higher efficiency of the Levy search compared to symmetric Levy flights at both short and long distances, and the effect is more pronounced for stable indices alpha close to unity.}, language = {en} } @article{HerbstBaalmannBykovetal.2022, author = {Herbst, Konstantin and Baalmann, Lennart R. and Bykov, Andrei and Engelbrecht, N. Eugene and Ferreira, Stefan E. S. and Izmodenov, Vladislav V. and Korolkov, Sergey D. and Levenfish, Ksenia P. and Linsky, Jeffrey L. and Meyer, Dominique M. -A. and Scherer, Klaus and Strauss, R. Du Toit}, title = {Astrospheres of planet-hosting cool stars and beyond when modeling meets observations}, series = {Space science reviews}, volume = {218}, journal = {Space science reviews}, number = {4}, publisher = {Springer Nature}, address = {Dordrecht}, issn = {0038-6308}, doi = {10.1007/s11214-022-00894-3}, pages = {46}, year = {2022}, abstract = {Thanks to dedicated long-term missions like Voyager and GOES over the past 50 years, much insight has been gained on the activity of our Sun, the solar wind, its interaction with the interstellar medium, and, thus, about the formation, the evolution, and the structure of the heliosphere. Additionally, with the help of multi-wavelength observations by the Hubble Space Telescope, Kepler, and TESS, we not only were able to detect a variety of extrasolar planets and exomoons but also to study the characteristics of their host stars, and thus became aware that other stars drive bow shocks and astrospheres. Although features like, e.g., stellar winds, could not be measured directly, over the past years several techniques have been developed allowing us to indirectly derive properties like stellar mass-loss rates and stellar wind speeds, information that can be used as direct input to existing astrospheric modeling codes. In this review, the astrospheric modeling efforts of various stars will be presented. Starting with the heliosphere as a benchmark of astrospheric studies, investigating the paleo-heliospheric changes and the Balmer H alpha projections to 1 pc, we investigate the surroundings of cool and hot stars, but also of more exotic objects like neutron stars. While pulsar wind nebulae (PWNs) might be a source of high-energy galactic cosmic rays (GCRs), the astrospheric environments of cool and hot stars form a natural shield against GCRs. Their modulation within these astrospheres, and the possible impact of turbulence, are also addressed. This review shows that all of the presented modeling efforts are in excellent agreement with currently available observations.}, language = {en} } @article{GriggioBedinRaddietal.2022, author = {Griggio, Massimo and Bedin, Luigi R. and Raddi, Roberto and Reindl, Nicole and Tomasella, Lina and Scalco, M. and Salaris, M. and Cassisi, S. and Ochner, P. and Ciroi, S. and Rosati, P. and Nardiello, Domenico and Anderson, J. and Libralato, Mattia and Bellini, A. and Vallenari, A. and Spina, L. and Pedani, M.}, title = {Astro-photometric study of M37 with Gaia and wide-field ugi-imaging}, series = {Monthly notices of the Royal Astronomical Society}, volume = {515}, journal = {Monthly notices of the Royal Astronomical Society}, number = {2}, publisher = {Oxford University Press}, address = {Oxford}, issn = {0035-8711}, doi = {10.1093/mnras/stac1920}, pages = {1841 -- 1853}, year = {2022}, abstract = {We present an astrometric and photometric wide-field study of the Galactic open star cluster M37 (NGC 2099). The studied field was observed with ground-based images covering a region of about four square degrees in the Sloan-like filters ugi. We exploited the Gaia catalogue to calibrate the geometric distortion of the large field mosaics, developing software routines that can be also applied to other wide-field instruments. The data are used to identify the hottest white dwarf (WD) member candidates of M37. Thanks to the Gaia EDR3 exquisite astrometry we identified seven such WD candidates, one of which, besides being a high-probability astrometric member, is the putative central star of a planetary nebula. To our knowledge, this is a unique object in an open cluster, and we have obtained follow-up low-resolution spectra that are used for a qualitative characterization of this young WD. Finally, we publicly release a three-colour atlas and a catalogue of the sources in the field of view, which represents a complement of existing material.}, language = {en} } @article{WachsBilzWettsteinetal.2022, author = {Wachs, Sebastian and Bilz, Ludwig and Wettstein, Alexander and Wright, Michelle F. and Kansok-Dusche, Julia and Krause, Norman and Ballaschk, Cindy}, title = {Associations between witnessing and perpetrating online hate speech among adolescents}, series = {Psychology of violence}, volume = {12}, journal = {Psychology of violence}, number = {6}, publisher = {American Psychological Association}, address = {Washington}, issn = {2152-0828}, doi = {10.1037/vio0000422}, pages = {371 -- 381}, year = {2022}, abstract = {Objective: The open expression of hatred, hostility, and violence against minorities has become a common online phenomenon. Adolescents are at particular risk of being involved in different hate speech roles (e.g., witness, perpetrator). However, the correlates of their involvement as perpetrators and the mechanisms that might explain their involvement in hate speech across different roles have not yet been thoroughly investigated. To this end, this study investigates moral disengagement and empathy as correlates of online hate speech perpetration and the moderation effects of empathy and moral disengagement in the relationship between witnessing and perpetrating online hate speech. Method: The sample consists of 3,560 7th to 9th graders from 40 schools in Germany and Switzerland. Self-report questionnaires were utilized to assess online hate speech involvement, moral disengagement, and empathy. Results: Multilevel regression analyses revealed that moral disengagement and witnessing online hate speech were positively associated with online hate speech perpetration, while empathy was negatively associated with it. The findings also showed that the positive relationship between witnessing and perpetrating online hate speech was stronger at higher levels of moral disengagement and weaker when moral disengagement was low. The association between witnessing and perpetrating online hate speech was weaker when adolescents had higher rather than lower levels of empathy. Conclusions: The findings underscore the need for prevention efforts to accelerate moral engagement and empathy as critical future directions in hate speech prevention. This study also contributes to our understanding of underlying mechanisms that explain adolescents' involvement across different roles in hate speech.}, language = {en} } @article{WickKriemlerGranacher2022, author = {Wick, Kristin and Kriemler, Susi and Granacher, Urs}, title = {Associations between measures of physical fitness and cognitive performance in preschool children}, series = {BMC sports science, medicine \& rehabilitation}, volume = {14}, journal = {BMC sports science, medicine \& rehabilitation}, number = {1}, publisher = {BMC}, address = {London}, issn = {2052-1847}, doi = {10.1186/s13102-022-00470-w}, pages = {8}, year = {2022}, abstract = {Background: Given that recent studies report negative secular declines in physical fitness, associations between fitness and cognition in childhood are strongly discussed. The preschool age is characterized by high neuroplasticity which effects motor skill learning, physical fitness, and cognitive development. The aim of this study was to assess the relation of physical fitness and attention (including its individual dimensions (quantitative, qualitative)) as one domain of cognitive performance in preschool children. We hypothesized that fitness components which need precise coordination compared to simple fitness components are stronger related to attention. Methods: Physical fitness components like static balance (i.e., single-leg stance), muscle strength (i.e., handgrip strength), muscle power (i.e., standing long jump), and coordination (i.e., hopping on one leg) were assessed in 61 healthy children (mean age 4.5 +/- 0.6 years; girls n = 30). Attention was measured with the "Konzentrations-Handlungsverfahren fur Vorschulkinder" [concentration-action procedure for preschoolers]). Analyses were adjusted for age, body height, and body mass. Results: Results from single linear regression analysis revealed a significant (p < 0.05) association between physical fitness (composite score) and attention (composite score) (standardized ss = 0.40), showing a small to medium effect (F-2 = 0.14). Further, coordination had a significant relation with the composite score and the quantitative dimension of attention (standardized ss = 0.35; p < 0.01; standardized ss = - 0.33; p < 0.05). Coordination explained about 11\% (composite score) and 9\% (quantitative dimension) of the variance in the stepwise multiple regression model. Conclusion: The results indicate that performance in physical fitness, particularly coordination, is related to attention in preschool children. Thus, high performance in complex fitness components (i.e., hopping on one leg) tends to predict attention in preschool children. Further longitudinal studies should focus on the effectiveness of physical activity programs implementing coordination and complex exercises at preschool age to examine cause-effect relationships between physical fitness and attention precisely.}, language = {en} } @article{WachsMachimbarrenaWrightetal.2022, author = {Wachs, Sebastian and Machimbarrena, Juan Manuel and Wright, Michelle F. and G{\´a}mez-Guadix, Manuel and Yang, Soeun and Sittichai, Ruthaychonnee and Singh, Ritu and Biswal, Ramakrishna and Flora, Katerina and Daskalou, Vassiliki and Maziridou, Evdoxia and Sung Hong, Jun and Krause, Norman}, title = {Associations between coping strategies and cyberhate involvement}, series = {International journal of environmental research and public health}, volume = {19}, journal = {International journal of environmental research and public health}, edition = {11}, publisher = {MDPI}, address = {Basel, Schweiz}, issn = {1660-4601}, doi = {10.3390/ijerph19116749}, pages = {1 -- 14}, year = {2022}, abstract = {Cyberhate represents a risk to adolescents' development and peaceful coexistence in democratic societies. Yet, not much is known about the relationship between adolescents' ability to cope with cyberhate and their cyberhate involvement. To fill current gaps in the literature and inform the development of media education programs, the present study investigated various coping strategies in a hypothetical cyberhate scenario as correlates for being cyberhate victims, perpetrators, and both victim-perpetrators. The sample consisted of 6829 adolescents aged 12-18 years old (Mage = 14.93, SD = 1.64; girls: 50.4\%, boys: 48.9\%, and 0.7\% did not indicate their gender) from Asia, Europe, and North America. Results showed that adolescents who endorsed distal advice or endorsed technical coping showed a lower likelihood to be victims, perpetrators, or victim-perpetrators. In contrast, if adolescents felt helpless or endorsed retaliation to cope with cyberhate, they showed higher odds of being involved in cyberhate as victims, perpetrators, or victim-perpetrators. Finally, adolescents who endorsed close support as a coping strategy showed a lower likelihood to be victim-perpetrators, and adolescents who endorsed assertive coping showed higher odds of being victims. In conclusion, the results confirm the importance of addressing adolescents' ability to deal with cyberhate to develop more tailored prevention approaches. More specifically, such initiatives should focus on adolescents who feel helpless or feel inclined to retaliate. In addition, adolescents should be educated to practice distal advice and technical coping when experiencing cyberhate. Implications for the design and instruction of evidence-based cyberhate prevention (e.g., online educational games, virtual learning environments) will be discussed.}, language = {en} } @article{HoffmannTschornMichalskietal.2022, author = {Hoffmann, Stephanie and Tschorn, Mira and Michalski, Niels and Hoebel, Jens and F{\"o}rstner, Bernd Rainer and Rapp, Michael A. and Spallek, Jacob}, title = {Association of regional socioeconomic deprivation and rurality with global developmental delay in early childhood}, series = {Health \& place : an international journal ; a social science \& medicine publication ; incorporating Geographia medica}, volume = {75}, journal = {Health \& place : an international journal ; a social science \& medicine publication ; incorporating Geographia medica}, publisher = {Elsevier Science}, address = {Amsterdam [u.a.]}, issn = {1353-8292}, doi = {10.1016/j.healthplace.2022.102794}, pages = {8}, year = {2022}, abstract = {Background: From birth to young adulthood, health and development of young people are strongly linked to their living situation, including their family's socioeconomic position (SEP) and living environment. The impact of regional characteristics on development in early childhood beyond family SEP has been rarely investigated. This study aimed to identify regional predictors of global developmental delay at school entry taking family SEP into consideration. Method: We used representative, population-based data from mandatory school entry examinations of the German federal state of Brandenburg in 2018/2019 with n=22,801 preschool children. By applying binary multilevel models, we hierarchically analyzed the effect of regional deprivation defined by the German Index of Socioeconomic Deprivation (GISD) and rurality operationalized as inverted population density of the children's school district on global developmental delay (GDD) while adjusting for family SEP (low, medium and high) Results: Family SEP was significantly and strongly linked to GDD. Children with the highest family SEP showed a lower odds for GDD compared to a medium SEP (female: OR=4.26, male: OR=3.46) and low SEP (female: OR=16.58, male: OR=12.79). Furthermore, we discovered a smaller, but additional and independent effect of regional socioeconomic deprivation on GDD, with a higher odds for children from a more deprived school district (female: OR=1.35, male: OR=1.20). However, rurality did not show a significant link to GDD in preschool children beyond family SEP and regional deprivation. Conclusion: Family SEP and regional deprivation are risk factors for child development and of particular interest to promote health of children in early childhood and over the life course.}, language = {en} } @article{OseiBlockWippert2022, author = {Osei, Francis and Block, Andrea and Wippert, Pia-Maria}, title = {Association of primary allostatic load mediators and metabolic syndrome (MetS): A systematic review}, series = {Frontiers in Endocrinology}, volume = {13}, journal = {Frontiers in Endocrinology}, publisher = {Frontiers}, address = {Lausanne, Schweiz}, issn = {1664-2392}, doi = {10.3389/fendo.2022.946740}, pages = {16}, year = {2022}, abstract = {Allostatic load (AL) exposure may cause detrimental effects on the neuroendocrine system, leading to metabolic syndrome (MetS). The primary mediators of AL involve serum dehydroepiandrosterone sulfate (DHEAS; a functional HPA axis antagonist); further, cortisol, urinary norepinephrine (NE), and epinephrine (EPI) excretion levels (assessed within 12-h urine as a golden standard for the evaluation of the HPA axis activity and sympathetic nervous system activity). However, the evidence of an association between the primary mediators of AL and MetS is limited. This systematic review aimed to critically examine the association between the primary mediators of AL and MetS. PubMed and Web of Science were searched for articles from January 2010 to December 2021, published in English. The search strategy focused on cross-sectional and case-control studies comprising adult participants with MetS, obesity, overweight, and without chronic diseases. The STROBE checklist was used to assess study quality control. Of 770 studies, twenty-one studies with a total sample size (n = 10,666) met the eligibility criteria. Eighteen studies were cross-sectional, and three were case-control studies. The included studies had a completeness of reporting score of COR \% = 87.0 ± 6.4\%. It is to be noted, that cortisol as a primary mediator of AL showed an association with MetS in 50\% (urinary cortisol), 40\% (serum cortisol), 60\% (salivary cortisol), and 100\% (hair cortisol) of the studies. For DHEAS, it is to conclude that 60\% of the studies showed an association with MetS. In contrast, urinary EPI and urinary NE had 100\% no association with MetS. In summary, there is a tendency for the association between higher serum cortisol, salivary cortisol, urinary cortisol, hair cortisol, and lower levels of DHEAS with MetS. Future studies focusing on longitudinal data are warranted for clarification and understanding of the association between the primary mediators of AL and MetS.}, language = {en} } @article{BenNsirJomaaYildirimetal.2022, author = {Ben Nsir, Siwar and Jomaa, Seifeddine and Yildirim, Umit and Zhou, Xiangqian and D'Oria, Marco and Rode, Michael and Khlifi, Slaheddine}, title = {Assessment of climate change impact on discharge of the lakhmass catchment (Northwest Tunisia)}, series = {Water}, volume = {14}, journal = {Water}, number = {14}, publisher = {MDPI}, address = {Basel}, issn = {2073-4441}, doi = {10.3390/w14142242}, pages = {17}, year = {2022}, abstract = {The Mediterranean region is increasingly recognized as a climate change hotspot but is highly underrepresented in hydrological climate change studies. This study aims to investigate the climate change effects on the hydrology of Lakhmass catchment in Tunisia. Lakhmass catchment is a part of the Medium Valley of Medjerda in northwestern Tunisia that drains an area of 126 km(2). First, the Hydrologiska Byrans Vattenbalansavdelning light (HBV-light) model was calibrated and validated successfully at a daily time step to simulate discharge during the 1981-1986 period. The Nash Sutcliffe Efficiency and Percent bias (NSE, PBIAS) were (0.80, +2.0\%) and (0.53, -9.5\%) for calibration (September 1982-August 1984) and validation (September 1984-August 1986) periods, respectively. Second, HBV-light model was considered as a predictive tool to simulate discharge in a baseline period (1981-2009) and future projections using data (precipitation and temperature) from thirteen combinations of General Circulation Models (GCMs) and Regional Climatic Models (RCMs). We used two trajectories of Representative Concentration Pathways, RCP4.5 and RCP8.5, suggested by the Intergovernmental Panel on Climate Change (IPCC). Each RCP is divided into three projection periods: near-term (2010-2039), mid-term (2040-2069) and long-term (2070-2099). For both scenarios, a decrease in precipitation and discharge will be expected with an increase in air temperature and a reduction in precipitation with almost 5\% for every +1 degrees C of global warming. By long-term (2070-2099) projection period, results suggested an increase in temperature with about 2.7 degrees C and 4 degrees C, and a decrease in precipitation of approximately 7.5\% and 15\% under RCP4.5 and RCP8.5, respectively. This will likely result in a reduction of discharge of 12.5\% and 36.6\% under RCP4.5 and RCP8.5, respectively. This situation calls for early climate change adaptation measures under a participatory approach, including multiple stakeholders and water users.}, language = {en} } @article{HenschkeKaplickWochatzetal.2022, author = {Henschke, Jakob and Kaplick, Hannes and Wochatz, Monique and Engel, Tilman}, title = {Assessing the validity of inertial measurement units for shoulder kinematics using a commercial sensor-software system}, series = {Health science reports}, volume = {5}, journal = {Health science reports}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {2398-8835}, doi = {10.1002/hsr2.772}, pages = {1 -- 11}, year = {2022}, abstract = {Background and Aims Wearable inertial sensors may offer additional kinematic parameters of the shoulder compared to traditional instruments such as goniometers when elaborate and time-consuming data processing procedures are undertaken. However, in clinical practice simple-real time motion analysis is required to improve clinical reasoning. Therefore, the aim was to assess the criterion validity between a portable "off-the-shelf" sensor-software system (IMU) and optical motion (Mocap) for measuring kinematic parameters during active shoulder movements. Methods 24 healthy participants (9 female, 15 male, age 29 +/- 4 years, height 177 +/- 11 cm, weight 73 +/- 14 kg) were included. Range of motion (ROM), total range of motion (TROM), peak and mean angular velocity of both systems were assessed during simple (abduction/adduction, horizontal flexion/horizontal extension, vertical flexion/extension, and external/internal rotation) and complex shoulder movements. Criterion validity was determined using intraclass-correlation coefficients (ICC), root mean square error (RMSE) and Bland and Altmann analysis (bias; upper and lower limits of agreement). Results ROM and TROM analysis revealed inconsistent validity during simple (ICC: 0.040-0.733, RMSE: 9.7 degrees-20.3 degrees, bias: 1.2 degrees-50.7 degrees) and insufficient agreement during complex shoulder movements (ICC: 0.104-0.453, RMSE: 10.1 degrees-23.3 degrees, bias: 1.0 degrees-55.9 degrees). Peak angular velocity (ICC: 0.202-0.865, RMSE: 14.6 degrees/s-26.7 degrees/s, bias: 10.2 degrees/s-29.9 degrees/s) and mean angular velocity (ICC: 0.019-0.786, RMSE:6.1 degrees/s-34.2 degrees/s, bias: 1.6 degrees/s-27.8 degrees/s) were inconsistent. Conclusions The "off-the-shelf" sensor-software system showed overall insufficient agreement with the gold standard. Further development of commercial IMU-software-solutions may increase measurement accuracy and permit their integration into everyday clinical practice.}, language = {en} } @article{PawlakNoetzelDragoetal.2022, author = {Pawlak, Julia and Noetzel, Dominique Christian and Drago, Claudia and Weithoff, Guntram}, title = {Assessing the toxicity of polystyrene beads and silica particles on the microconsumer Brachionus calyciflorus at different timescales}, series = {Frontiers in Environmental Science}, journal = {Frontiers in Environmental Science}, publisher = {Frontiers}, address = {Lausanne, Schweiz}, issn = {2296-665X}, doi = {10.3389/fenvs.2022.955425}, pages = {1 -- 11}, year = {2022}, abstract = {Environmental pollution by microplastics has become a severe problem in terrestrial and aquatic ecosystems and, according to actual prognoses, problems will further increase in the future. Therefore, assessing and quantifying the risk for the biota is crucial. Standardized short-term toxicological procedures as well as methods quantifying potential toxic effects over the whole life span of an animal are required. We studied the effect of the microplastic polystyrene on the survival and reproduction of a common freshwater invertebrate, the rotifer Brachionus calyciflorus, at different timescales. We used pristine polystyrene spheres of 1, 3, and 6 µm diameter and fed them to the animals together with food algae in different ratios ranging from 0 to 50\% nonfood particles. As a particle control, we used silica to distinguish between a pure particle effect and a plastic effect. After 24 h, no toxic effect was found, neither with polystyrene nor with silica. After 96 h, a toxic effect was detectable for both particle types. The size of the particles played a negligible role. Studying the long-term effect by using life table experiments, we found a reduced reproduction when the animals were fed with 3 µm spheres together with similar-sized food algae. We conclude that the fitness reduction is mainly driven by the dilution of food by the nonfood particles rather than by a direct toxic effect.}, language = {en} } @article{PohlMaciasColemanetal.2022, author = {Pohl, Martin and Macias, Oscar and Coleman, Phaedra and Gordon, Chris}, title = {Assessing the impact of hydrogen absorption on the characteristics of the Galactic center excess}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {929}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.3847/1538-4357/ac6032}, pages = {13}, year = {2022}, abstract = {We present a new reconstruction of the distribution of atomic hydrogen in the inner Galaxy that is based on explicit radiation transport modeling of line and continuum emission and a gas-flow model in the barred Galaxy that provides distance resolution for lines of sight toward the Galactic center. The main benefits of the new gas model are (a) the ability to reproduce the negative line signals seen with the HI4PI survey and (b) the accounting for gas that primarily manifests itself through absorption. We apply the new model of Galactic atomic hydrogen to an analysis of the diffuse gamma-ray emission from the inner Galaxy, for which an excess at a few GeV was reported that may be related to dark matter. We find with high significance an improved fit to the diffuse gamma-ray emission observed with the Fermi-LAT, if our new H i model is used to estimate the cosmic-ray induced diffuse gamma-ray emission. The fit still requires a nuclear bulge at high significance. Once this is included there is no evidence of a dark-matter signal, be it cuspy or cored. But an additional so-called boxy bulge is still favored by the data. This finding is robust under the variation of various parameters, for example, the excitation temperature of atomic hydrogen, and a number of tests for systematic issues.}, language = {en} } @article{FranckeHeistermannKoehlietal.2022, author = {Francke, Till and Heistermann, Maik and K{\"o}hli, Markus and Budach, Christian and Schr{\"o}n, Martin and Oswald, Sascha}, title = {Assessing the feasibility of a directional cosmic-ray neutron sensing sensor for estimating soil moisture}, series = {Geoscientific Instrumentation, Methods and Data Systems}, volume = {11}, journal = {Geoscientific Instrumentation, Methods and Data Systems}, publisher = {Copernicus Publ.}, address = {G{\"o}ttingen}, issn = {2193-0864}, doi = {10.5194/gi-11-75-2022}, pages = {75 -- 92}, year = {2022}, abstract = {Cosmic-ray neutron sensing (CRNS) is a non-invasive tool for measuring hydrogen pools such as soil moisture, snow or vegetation. The intrinsic integration over a radial hectare-scale footprint is a clear advantage for averaging out small-scale heterogeneity, but on the other hand the data may become hard to interpret in complex terrain with patchy land use. This study presents a directional shielding approach to prevent neutrons from certain angles from being counted while counting neutrons entering the detector from other angles and explores its potential to gain a sharper horizontal view on the surrounding soil moisture distribution. Using the Monte Carlo code URANOS (Ultra Rapid Neutron-Only Simulation), we modelled the effect of additional polyethylene shields on the horizontal field of view and assessed its impact on the epithermal count rate, propagated uncertainties and aggregation time. The results demonstrate that directional CRNS measurements are strongly dominated by isotropic neutron transport, which dilutes the signal of the targeted direction especially from the far field. For typical count rates of customary CRNS stations, directional shielding of half-spaces could not lead to acceptable precision at a daily time resolution. However, the mere statistical distinction of two rates should be feasible.}, language = {en} } @article{FanselowZimmermannPhilipp2022, author = {Fanselow, Gisbert and Zimmermann, Malte and Philipp, Mareike}, title = {Assessing the availability of inverse scope in German in the covered box paradigm}, series = {Glossa : a journal of general linguistics}, volume = {7}, journal = {Glossa : a journal of general linguistics}, number = {1}, publisher = {Open Library of Humanities}, address = {London}, issn = {2397-1835}, doi = {10.16995/glossa.5766}, pages = {1 -- 24}, year = {2022}, abstract = {This paper presents the results of a novel experimental approach to relative quantifier scope in German that elicits data in an indirect manner. Applying the covered-box method (Huang et al. 2013) to scope phenomena, we show that inverse scope is available to some extent in the free constituent order language German, thereby validating earlier findings on other syntactic configurations in German (Rado \& Bott 2018) and empirical claims on other free constituent order languages (Japanese, Russian, Hindi), as well as recent corpus findings in Webelhuth (2020). Moreover, the results of the indirect covered-box experiment replicate findings from an earlier direct-query experiment with comparable target items, in which participants were asked directly about the availability of surface scope and inverse scope readings. The configuration of interest consisted of canonical transitive clauses with deaccented existential subject and universal object QPs, in which the restriction of the universal QP was controlled for by the context.}, language = {en} } @article{HeinzeWeckKuehne2022, author = {Heinze, Peter Eric and Weck, Florian and K{\"u}hne, Franziska}, title = {Assessing patient preferences}, series = {Frontiers in psychology}, volume = {12}, journal = {Frontiers in psychology}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2021.795776}, pages = {10}, year = {2022}, abstract = {Despite the positive effects of including patients' preferences into therapy on psychotherapy outcomes, there are still few thoroughly validated assessment tools at hand. We translated the 18-item Cooper-Norcross Inventory of Preferences (C-NIP) into German and aimed at replicating its factor structure. Further, we investigated the reliability of the questionnaire and its convergence with trait measures. A heterogeneous sample of N = 969 participants took part in our online survey. Performing ESEM models, we found acceptable model fit for a four-factor structure similar to the original factor structure. Furthermore, we propose an alternative model following the adjustment of single items. The German C-NIP showed acceptable to good reliability, as well as small correlations with Big-Five personality traits, trait and attachment anxiety, locus of control, and temporal focus. However, we recommend further replication of the factor structure and further validation of the C-NIP.}, language = {en} } @article{HeinzeWeckKuehne2022, author = {Heinze, Peter Eric and Weck, Florian and K{\"u}hne, Franziska}, title = {Assessing Patient Preferences}, series = {Frontiers in Psychology}, volume = {12}, journal = {Frontiers in Psychology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2021.795776}, pages = {10}, year = {2022}, abstract = {Despite the positive effects of including patients' preferences into therapy on psychotherapy outcomes, there are still few thoroughly validated assessment tools at hand. We translated the 18-item Cooper-Norcross Inventory of Preferences (C-NIP) into German and aimed at replicating its factor structure. Further, we investigated the reliability of the questionnaire and its convergence with trait measures. A heterogeneous sample of N = 969 participants took part in our online survey. Performing ESEM models, we found acceptable model fit for a four-factor structure similar to the original factor structure. Furthermore, we propose an alternative model following the adjustment of single items. The German C-NIP showed acceptable to good reliability, as well as small correlations with Big-Five personality traits, trait and attachment anxiety, locus of control, and temporal focus. However, we recommend further replication of the factor structure and further validation of the C-NIP.}, language = {en} } @article{TetzlaffHartmannDumontetal.2022, author = {Tetzlaff, Leonard and Hartmann, Ulrike and Dumont, Hanna and Brod, Garvin}, title = {Assessing individualized instruction in the classroom}, series = {Learning and instruction : the journal of the European Association for Research on Learning and Instruction (EARLI)}, volume = {82}, journal = {Learning and instruction : the journal of the European Association for Research on Learning and Instruction (EARLI)}, publisher = {Elsevier}, address = {Oxford}, issn = {0959-4752}, doi = {10.1016/j.learninstruc.2022.101655}, pages = {10}, year = {2022}, abstract = {In this article, we address the measurement of individualized instruction in the context of regular classroom instruction. Our study assessed instructional practices geared towards individualization in German third grade reading lessons by combining self-report data from 621 students, from their teachers (n = 57), and live obser-vations. We then investigated the reliability of these different approaches to measuring individualization as well as the agreement between them. All three approaches yielded reliable indicators of individualized practices, but not all of them corresponded with each other. We found considerable agreement between students and observers, but neither agreed with teachers' self-reports. Upon closer examination, we found that students' ratings only correlated with teacher ratings that were provided close to the timepoint of interest. This correlation increased when teacher measures were corrected for response tendencies. We conclude with some recommendations for future studies that aim to measure individualized instruction in the classroom.}, language = {en} } @article{JesusSchmidtFickeletal.2022, author = {Jesus, Sonia A. and Schmidt, Anke and Fickel, J{\"o}rns and Doherr, Marcus G. and Boonprasert, Khajohnpat and Thitaram, Chatchote and Sariya, Ladawan and Ratanakron, Parntep and Hildebrandt, Thomas Bernd}, title = {Assessing coagulation parameters in healthy Asian Elephants (Elephas maximus) from European and thai populations}, series = {Animals}, volume = {12}, journal = {Animals}, number = {3}, publisher = {MDPI}, address = {Basel}, issn = {2076-2615}, doi = {10.3390/ani12030361}, pages = {16}, year = {2022}, abstract = {Simple Summary Asian elephants (Elephas maximus) are considered endangered and their population is in continuous decline. Understanding their social interactions, health, and welfare status has been a topic of intense research in recent decades. Coagulation assessments have been underutilized in wildlife but can give valuable information on individual health. This study aims to increase the knowledge of the coagulation status in healthy Asian elephants from different backgrounds and age groups, using a fast point-of-care analyzer. This tool can be further used in either routine health check-ups performed by caretakers or in a clinical emergency, such as in cases of elephant endotheliotropic herpesvirus hemorrhagic disease outbreaks. We have also investigated the presence of genomic mutations in one coagulation factor-factor VII-where a disorder was previously reported in an Asian elephant. Hereby, we report new reference values for coagulation parameters, such as coagulation times and fibrinogen concentration of Asian elephants assessed in Thailand and in Europe, as well as several single point mutations found in the exons of Elephas maximus coagulation F7 gene. We found the point-of-care analyzer used in this study to be very practical and user friendly for a zoo and field environment and hope that this project will incentivize further coagulation studies in Asian elephants and in other wildlife species. The Asian elephant population is continuously declining due to several extrinsic reasons in their range countries, but also due to diseases in captive populations worldwide. One of these diseases, the elephant endotheliotropic herpesvirus (EEHV) hemorrhagic disease, is very impactful because it particularly affects Asian elephant calves. It is commonly fatal and presents as an acute and generalized hemorrhagic syndrome. Therefore, having reference values of coagulation parameters, and obtaining such values for diseased animals in a very short time, is of great importance. We analyzed prothrombin time (PT), activated partial thromboplastin time (aPTT), and fibrinogen concentrations using a portable and fast point-of-care analyzer (VetScan Pro) in 127 Asian elephants from Thai camps and European captive herds. We found significantly different PT and aPTT coagulation times between elephants from the two regions, as well as clear differences in fibrinogen concentration. Nevertheless, these alterations were not expected to have biological or clinical implications. We have also sequenced the coagulation factor VII gene of 141 animals to assess the presence of a previously reported hereditary coagulation disorder in Asian elephants and to investigate the presence of other mutations. We did not find the previously reported mutation in our study population. Instead, we discovered the presence of several new single nucleotide polymorphisms, two of them being considered as deleterious by effect prediction software.}, language = {en} } @article{HoffmannOttRaupbachetal.2022, author = {Hoffmann, Holger and Ott, Christiane and Raupbach, Jana and Andernach, Lars and Renz, Matthias and Grune, Tilman and Hanschen, Franziska S.}, title = {Assessing bioavailability and bioactivity of 4-Hydroxythiazolidine-2-Thiones, newly discovered glucosinolate degradation products formed during domestic boiling of cabbage}, series = {Frontiers in nutrition}, volume = {9}, journal = {Frontiers in nutrition}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-861X}, doi = {10.3389/fnut.2022.941286}, pages = {13}, year = {2022}, abstract = {Glucosinolates are plant secondary metabolites found in cruciferous vegetables (Brassicaceae) that are valued for their potential health benefits. Frequently consumed representatives of these vegetables, for example, are white or red cabbage, which are typically boiled before consumption. Recently, 3-alk(en)yl-4-hydroxythiazolidine-2-thiones were identified as a class of thermal glucosinolate degradation products that are formed during the boiling of cabbage. Since these newly discovered compounds are frequently consumed, this raises questions about their potential uptake and their possible bioactive functions. Therefore, 3-allyl-4-hydroxythiazolidine-2-thione (allyl HTT) and 4-hydroxy-3-(4-(methylsulfinyl) butyl)thiazolidine-2-thione (4-MSOB HTT) as degradation products of the respective glucosinolates sinigrin and glucoraphanin were investigated. After consumption of boiled red cabbage broth, recoveries of consumed amounts of the degradation products in urine collected for 24 h were 18 +/- 5\% for allyl HTT and 21 +/- 4\% for 4-MSOB HTT (mean +/- SD, n = 3). To investigate the stability of the degradation products during uptake and to elucidate the uptake mechanism, both an in vitro stomach and an in vitro intestinal model were applied. The results indicate that the uptake of allyl HTT and 4-MSOB HTT occurs by passive diffusion. Both compounds show no acute cell toxicity, no antioxidant potential, and no change in NAD(P)H dehydrogenase quinone 1 (NQO1) activity up to 100 mu M. However, inhibition of glycogen synthase kinases-3 (GSK-3) in the range of 20\% for allyl HTT for the isoform GSK-3 beta and 29\% for 4-MSOB HTT for the isoform GSK-3 alpha at a concentration of 100 mu M was found. Neither health-promoting nor toxic effects of 3-alk(en)yl-4-hydroxythiazolidine-2-thiones were found in the four tested assays carried out in this study, which contrasts with the properties of other glucosinolate degradation products, such as isothiocyanates.}, language = {en} } @article{KothariBattistiBooteetal.2022, author = {Kothari, Kritika and Battisti, Rafael and Boote, Kenneth J. and Archontoulis, Sotirios and Confalone, Adriana and Constantin, Julie and Cuadra, Santiago and Debaeke, Philippe and Faye, Babacar and Grant, Brian and Hoogenboom, Gerrit and Jing, Qi and van der Laan, Michael and Macena da Silva, Fernando Antonio and Marin, Fabio R. and Nehbandani, Alireza and Nendel, Claas and Purcell, Larry C. and Qian, Budong and Ruane, Alex C. and Schoving, Celine and Silva, Evandro H. F. M. and Smith, Ward and Soltani, Afshin and Srivastava, Amit and Vieira, Nilson A. and Slone, Stacey and Salmeron, Montserrat}, title = {Are soybean models ready for climate change food impact assessments?}, series = {European journal of agronomy : the official journal of the European Society for Agronomy}, volume = {135}, journal = {European journal of agronomy : the official journal of the European Society for Agronomy}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1161-0301}, doi = {10.1016/j.eja.2022.126482}, pages = {15}, year = {2022}, abstract = {An accurate estimation of crop yield under climate change scenarios is essential to quantify our ability to feed a growing population and develop agronomic adaptations to meet future food demand. A coordinated evaluation of yield simulations from process-based eco-physiological models for climate change impact assessment is still missing for soybean, the most widely grown grain legume and the main source of protein in our food chain. In this first soybean multi-model study, we used ten prominent models capable of simulating soybean yield under varying temperature and atmospheric CO2 concentration [CO2] to quantify the uncertainty in soybean yield simulations in response to these factors. Models were first parametrized with high quality measured data from five contrasting environments. We found considerable variability among models in simulated yield responses to increasing temperature and [CO2]. For example, under a + 3 degrees C temperature rise in our coolest location in Argentina, some models simulated that yield would reduce as much as 24\%, while others simulated yield increases up to 29\%. In our warmest location in Brazil, the models simulated a yield reduction ranging from a 38\% decrease under + 3 degrees C temperature rise to no effect on yield. Similarly, when increasing [CO2] from 360 to 540 ppm, the models simulated a yield increase that ranged from 6\% to 31\%. Model calibration did not reduce variability across models but had an unexpected effect on modifying yield responses to temperature for some of the models. The high uncertainty in model responses indicates the limited applicability of individual models for climate change food projections. However, the ensemble mean of simulations across models was an effective tool to reduce the high uncertainty in soybean yield simulations associated with individual models and their parametrization. Ensemble mean yield responses to temperature and [CO2] were similar to those reported from the literature. Our study is the first demonstration of the benefits achieved from using an ensemble of grain legume models for climate change food projections, and highlights that further soybean model development with experiments under elevated [CO2] and temperature is needed to reduce the uncertainty from the individual models.}, language = {en} } @article{RolphOverduinRavensetal.2022, author = {Rolph, Rebecca and Overduin, Pier Paul and Ravens, Thomas and Lantuit, Hugues and Langer, Moritz}, title = {ArcticBeach v1.0}, series = {Frontiers in Earth Science}, volume = {10}, journal = {Frontiers in Earth Science}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-6463}, doi = {10.3389/feart.2022.962208}, pages = {19}, year = {2022}, abstract = {In the Arctic, air temperatures are increasing and sea ice is declining, resulting in larger waves and a longer open water season, all of which intensify the thaw and erosion of ice-rich coasts. Climate change has been shown to increase the rate of Arctic coastal erosion, causing problems for Arctic cultural heritage, existing industrial, military, and civil infrastructure, as well as changes in nearshore biogeochemistry. Numerical models that reproduce historical and project future Arctic erosion rates are necessary to understand how further climate change will affect these problems, and no such model yet exists to simulate the physics of erosion on a pan-Arctic scale. We have coupled a bathystrophic storm surge model to a simplified physical erosion model of a permafrost coastline. This Arctic erosion model, called ArcticBeach v1.0, is a first step toward a physical parameterization of Arctic shoreline erosion for larger-scale models. It is forced by wind speed and direction, wave period and height, sea surface temperature, all of which are masked during times of sea ice cover near the coastline. Model tuning requires observed historical retreat rates (at least one value), as well as rough nearshore bathymetry. These parameters are already available on a pan-Arctic scale. The model is validated at three study sites at 1) Drew Point (DP), Alaska, 2) Mamontovy Khayata (MK), Siberia, and 3) Veslebogen Cliffs, Svalbard. Simulated cumulative retreat rates for DP and MK respectively (169 and 170 m) over the time periods studied at each site (2007-2016, and 1995-2018) are found to the same order of magnitude as observed cumulative retreat (172 and 120 m). The rocky Veslebogen cliffs have small observed cumulative retreat rates (0.05 m over 2014-2016), and our model was also able to reproduce this same order of magnitude of retreat (0.08 m). Given the large differences in geomorphology between the study sites, this study provides a proof-of-concept that ArcticBeach v1.0 can be applied on very different permafrost coastlines. ArcticBeach v1.0 provides a promising starting point to project retreat of Arctic shorelines, or to evaluate historical retreat in places that have had few observations.}, language = {en} } @article{RadosavljevicLantuitKnoblauchetal.2022, author = {Radosavljevic, Boris and Lantuit, Hugues and Knoblauch, Christian and Couture, Nicole and Herzschuh, Ulrike and Fritz, Michael}, title = {Arctic nearshore sediment dynamics - an example from Herschel Island - Qikiqtaruk, Canada}, series = {Journal of marine science and engineering}, volume = {10}, journal = {Journal of marine science and engineering}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {2077-1312}, doi = {10.3390/jmse10111589}, pages = {18}, year = {2022}, abstract = {Increasing arctic coastal erosion rates imply a greater release of sediments and organic matter into the coastal zone. With 213 sediment samples taken around Herschel Island-Qikiqtaruk, Canadian Beaufort Sea, we aimed to gain new insights on sediment dynamics and geochemical properties of a shallow arctic nearshore zone. Spatial characteristics of nearshore sediment texture (moderately to poorly sorted silt) are dictated by hydrodynamic processes, but ice-related processes also play a role. We determined organic matter (OM) distribution and inferred the origin and quality of organic carbon by C/N ratios and stable carbon isotopes delta C-13. The carbon content was higher offshore and in sheltered areas (mean: 1.0 wt.\%., S.D.: 0.9) and the C/N ratios also showed a similar spatial pattern (mean: 11.1, S.D.: 3.1), while the delta C-13 (mean: -26.4 parts per thousand VPDB, S.D.: 0.4) distribution was more complex. We compared the geochemical parameters of our study with terrestrial and marine samples from other studies using a bootstrap approach. Sediments of the current study contained 6.5 times and 1.8 times less total organic carbon than undisturbed and disturbed terrestrial sediments, respectively. Therefore, degradation of OM and separation of carbon pools take place on land and continue in the nearshore zone, where OM is leached, mineralized, or transported beyond the study area.}, language = {en} } @article{SchannerKorteHolschneider2022, author = {Schanner, Maximilian and Korte, Monika and Holschneider, Matthias}, title = {ArchKalmag14k: A kalman-filter based global geomagnetic model for the holocene}, series = {Journal of geophysical research : Solid earth}, volume = {127}, journal = {Journal of geophysical research : Solid earth}, number = {2}, publisher = {American Geophysical Union}, address = {Washington}, issn = {2169-9313}, doi = {10.1029/2021JB023166}, pages = {17}, year = {2022}, abstract = {We propose a global geomagnetic field model for the last 14 thousand years, based on thermoremanent records. We call the model ArchKalmag14k. ArchKalmag14k is constructed by modifying recently proposed algorithms, based on space-time correlations. Due to the amount of data and complexity of the model, the full Bayesian posterior is numerically intractable. To tackle this, we sequentialize the inversion by implementing a Kalman-filter with a fixed time step. Every step consists of a prediction, based on a degree dependent temporal covariance, and a correction via Gaussian process regression. Dating errors are treated via a noisy input formulation. Cross correlations are reintroduced by a smoothing algorithm and model parameters are inferred from the data. Due to the specific statistical nature of the proposed algorithms, the model comes with space and time-dependent uncertainty estimates. The new model ArchKalmag14k shows less variation in the large-scale degrees than comparable models. Local predictions represent the underlying data and agree with comparable models, if the location is sampled well. Uncertainties are bigger for earlier times and in regions of sparse data coverage. We also use ArchKalmag14k to analyze the appearance and evolution of the South Atlantic anomaly together with reverse flux patches at the core-mantle boundary, considering the model uncertainties. While we find good agreement with earlier models for recent times, our model suggests a different evolution of intensity minima prior to 1650 CE. In general, our results suggest that prior to 6000 BCE the data is not sufficient to support global models.}, language = {en} } @article{SteinertStabernack2022, author = {Steinert, Fritjof and Stabernack, Benno}, title = {Architecture of a low latency H.264/AVC video codec for robust ML based image classification how region of interests can minimize the impact of coding artifacts}, series = {Journal of Signal Processing Systems for Signal, Image, and Video Technology}, volume = {94}, journal = {Journal of Signal Processing Systems for Signal, Image, and Video Technology}, number = {7}, publisher = {Springer}, address = {New York}, issn = {1939-8018}, doi = {10.1007/s11265-021-01727-2}, pages = {693 -- 708}, year = {2022}, abstract = {The use of neural networks is considered as the state of the art in the field of image classification. A large number of different networks are available for this purpose, which, appropriately trained, permit a high level of classification accuracy. Typically, these networks are applied to uncompressed image data, since a corresponding training was also carried out using image data of similar high quality. However, if image data contains image errors, the classification accuracy deteriorates drastically. This applies in particular to coding artifacts which occur due to image and video compression. Typical application scenarios for video compression are narrowband transmission channels for which video coding is required but a subsequent classification is to be carried out on the receiver side. In this paper we present a special H.264/Advanced Video Codec (AVC) based video codec that allows certain regions of a picture to be coded with near constant picture quality in order to allow a reliable classification using neural networks, whereas the remaining image will be coded using constant bit rate. We have combined this feature with the ability to run with lowest latency properties, which is usually also required in remote control applications scenarios. The codec has been implemented as a fully hardwired High Definition video capable hardware architecture which is suitable for Field Programmable Gate Arrays.}, language = {en} } @article{VatovaRubinGrossartetal.2022, author = {Vatova, Mariyana and Rubin, Conrad and Grossart, Hans-Peter and Goncalves, Susana C. and Schmidt, Susanne I. and Jarić, Ivan}, title = {Aquatic fungi: largely neglected targets for conservation}, series = {Frontiers in ecology and the environment}, volume = {20}, journal = {Frontiers in ecology and the environment}, number = {4}, publisher = {Wiley}, address = {Hoboken}, issn = {1540-9295}, doi = {10.1002/fee.2495}, pages = {207 -- 209}, year = {2022}, language = {en} } @article{GhafarianWielandLuettschwageretal.2022, author = {Ghafarian, Fatemeh and Wieland, Ralf and L{\"u}ttschwager, Dietmar and Nendel, Claas}, title = {Application of extreme gradient boosting and Shapley Additive explanations to predict temperature regimes inside forests from standard open-field meteorological data}, series = {Environmental modelling \& software with environment data news}, volume = {156}, journal = {Environmental modelling \& software with environment data news}, publisher = {Elsevier}, address = {Oxford}, issn = {1364-8152}, doi = {10.1016/j.envsoft.2022.105466}, pages = {11}, year = {2022}, abstract = {Forest microclimate can buffer biotic responses to summer heat waves, which are expected to become more extreme under climate warming. Prediction of forest microclimate is limited because meteorological observation standards seldom include situations inside forests. We use eXtreme Gradient Boosting - a Machine Learning technique - to predict the microclimate of forest sites in Brandenburg, Germany, using seasonal data comprising weather features. The analysis was amended by applying a SHapley Additive explanation to show the interaction effect of variables and individualised feature attributions. We evaluate model performance in comparison to artificial neural networks, random forest, support vector machine, and multi-linear regression. After implementing a feature selection, an ensemble approach was applied to combine individual models for each forest and improve robustness over a given single prediction model. The resulting model can be applied to translate climate change scenarios into temperatures inside forests to assess temperature-related ecosystem services provided by forests.}, language = {en} } @article{WochatzSchraplauEngeletal.2022, author = {Wochatz, Monique and Schraplau, Anne and Engel, Tilman and Zecher, Mahli Megan and Sharon, Hadar and Alt, Yasmin and Mayer, Frank and Kalron, Alon}, title = {Application of eccentric training in various clinical populations}, series = {PLoS ONE}, volume = {17}, journal = {PLoS ONE}, number = {12}, publisher = {Public Library of Science}, address = {San Francisco, California, USA}, issn = {1932-6203}, doi = {10.1371/journal.pone.0270875}, pages = {15}, year = {2022}, abstract = {Physical activity and exercise are effective approaches in prevention and therapy of multiple diseases. Although the specific characteristics of lengthening contractions have the potential to be beneficial in many clinical conditions, eccentric training is not commonly used in clinical populations with metabolic, orthopaedic, or neurologic conditions. The purpose of this pilot study is to investigate the feasibility, functional benefits, and systemic responses of an eccentric exercise program focused on the trunk and lower extremities in people with low back pain (LBP) and multiple sclerosis (MS). A six-week eccentric training program with three weekly sessions is performed by people with LBP and MS. The program consists of ten exercises addressing strength of the trunk and lower extremities. The study follows a four-group design (N = 12 per group) in two study centers (Israel and Germany): three groups perform the eccentric training program: A) control group (healthy, asymptomatic); B) people with LBP; C) people with MS; group D (people with MS) receives standard care physiotherapy. Baseline measurements are conducted before first training, post-measurement takes place after the last session both comprise blood sampling, self-reported questionnaires, mobility, balance, and strength testing. The feasibility of the eccentric training program will be evaluated using quantitative and qualitative measures related to the study process, compliance and adherence, safety, and overall program assessment. For preliminary assessment of potential intervention effects, surrogate parameters related to mobility, postural control, muscle strength and systemic effects are assessed. The presented study will add knowledge regarding safety, feasibility, and initial effects of eccentric training in people with orthopaedic and neurological conditions. The simple exercises, that are easily modifiable in complexity and intensity, are likely beneficial to other populations. Thus, multiple applications and implementation pathways for the herein presented training program are conceivable.}, language = {en} } @article{SongJieGaoetal.2022, author = {Song, Lina and Jie, Dongmei and Gao, Guizai and Liu, Lidan and Liu, Hongyan and Li, Dehui and Liu, Ying}, title = {Application of a topsoil phytolith dataset to quantitative paleoclimate reconstruction in Northeast China}, series = {Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences}, volume = {601}, journal = {Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0031-0182}, doi = {10.1016/j.palaeo.2022.111108}, pages = {12}, year = {2022}, abstract = {Although phytoliths are recognized as an important proxy for paleoenvironmental reconstruction, the quantitative relationship between phytoliths and climate is still debated. In order to provide an improved basis for phytolith-based paleoclimate reconstructions, a representative modern phytolith dataset is essential. Here, we synthesize a modern topsoil phytolith dataset for Northeast China, analyze its climatic significance, and apply it to a fossil phytolith series from the Hani peat core in Northeast China. The dataset comprises 660 topsoil phytolith assemblages from 289 sample sites. We compiled modern meteorological data to assess the quantitative relationship between the phytolith assemblages and climatic variables. Detrended correspondence analysis (DCA) and Redundancy analysis (RDA) were used to determine the dominant climatic variable influencing the phytolith distributions. The results showed that mean annual temperature (MAT) is the dominant variable controlling the spatial distribution of phytoliths, accounting for 8.91\% of the total variance. Transfer function based on inverse deshrinking locally-weighted weighted averaging (LWWA_Inv) was developed for MAT (R-_boot(2) = 0.86, RMSEP = 1.02 degrees C). Applying the LWWA_Inv transfer function to fossil phytolith records from the Hani peat core enables quantitative inferences to be made about Holocene climate changes in Northeast China. Overall, combined with the LWWA_Inv method, the topsoil phytolith dataset of Northeast China can be used for reliable quantitative MAT reconstruction.}, language = {en} } @article{DoerriesChechkinMetzler2022, author = {Doerries, Timo J. and Chechkin, Aleksei V. and Metzler, Ralf}, title = {Apparent anomalous diffusion and non-Gaussian distributions in a simple mobile-immobile transport model with Poissonian switching}, series = {Interface : journal of the Royal Society}, volume = {19}, journal = {Interface : journal of the Royal Society}, number = {192}, publisher = {Royal Society}, address = {London}, issn = {1742-5689}, doi = {10.1098/rsif.2022.0233}, pages = {14}, year = {2022}, abstract = {We analyse mobile-immobile transport of particles that switch between the mobile and immobile phases with finite rates. Despite this seemingly simple assumption of Poissonian switching, we unveil a rich transport dynamics including significant transient anomalous diffusion and non-Gaussian displacement distributions. Our discussion is based on experimental parameters for tau proteins in neuronal cells, but the results obtained here are expected to be of relevance for a broad class of processes in complex systems. Specifically, we obtain that, when the mean binding time is significantly longer than the mean mobile time, transient anomalous diffusion is observed at short and intermediate time scales, with a strong dependence on the fraction of initially mobile and immobile particles. We unveil a Laplace distribution of particle displacements at relevant intermediate time scales. For any initial fraction of mobile particles, the respective mean squared displacement (MSD) displays a plateau. Moreover, we demonstrate a short-time cubic time dependence of the MSD for immobile tracers when initially all particles are immobile.}, language = {en} } @article{HuelscherSobelKallniketal.2022, author = {H{\"u}lscher, Julian and Sobel, Edward and Kallnik, Niklas and Hoffmann, J. Elis and Millar, Ian L. and Hartmann, Kai and Bernhardt, Anne}, title = {Apatites record sedimentary provenance change 4-5 myrs before clay in the Oligocene/Miocene Alpine molasse}, series = {Frontiers in Earth Science}, volume = {10}, journal = {Frontiers in Earth Science}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-6463}, doi = {10.3389/feart.2022.914409}, pages = {16}, year = {2022}, abstract = {Extracting information about past tectonic or climatic environmental changes from sedimentary records is a key objective of provenance research. Interpreting the imprint of such changes remains challenging as signals might be altered in the sediment-routing system. We investigate the sedimentary provenance of the Oligocene/Miocene Upper Austrian Northern Alpine Foreland Basin and its response to the tectonically driven exhumation of the Tauern Window metamorphic dome (28 +/- 1 Ma) in the Eastern European Alps by using the unprecedented combination of Nd isotopic composition of bulk-rock clay-sized samples and partly previously published multi-proxy (Nd isotopic composition, trace-element geochemistry, U-Pb dating) sand-sized apatite single-grain analysis. The basin offers an excellent opportunity to investigate environmental signal propagation into the sedimentary record because comprehensive stratigraphic and seismic datasets can be combined with present research results. The bulk-rock clay-sized fraction epsilon Nd values of well-cutting samples from one well on the northern basin slope remained stable at similar to-9.7 from 27 to 19 Ma but increased after 19 Ma to similar to-9.1. In contrast, apatite single-grain distributions, which were extracted from 22 drill-core samples, changed significantly around 23.3 Ma from apatites dominantly from low-grade ( and TAMSD <<(delta(2)(Delta))over bar>> quantifiers-of FBM featuring < x(2) (Delta >> = <<(delta(2)(Delta >)over bar>> proportional to Delta(2H) (where H is the Hurst exponent and Delta is the [lag] time) changes in the presence of a power-law deterministically varying diffusivity D-proportional to(t) proportional to t(alpha-1) -germane to the process of scaled Brownian motion (SBM)-determining the strength of fractional Gaussian noise. The resulting compound "scaled-fractional" Brownian motion or FBM-SBM is found to be nonergodic, with < x(2)(Delta >> proportional to Delta(alpha+)(2H)(-1) and <(delta 2(Delta >) over bar > proportional to Delta(2H). We also detect a stalling behavior of the MSDs for very subdiffusive SBM and FBM, when alpha + 2H - 1 < 0. The distribution of particle displacements for FBM-SBM remains Gaussian, as that for the parent processes of FBM and SBM, in the entire region of scaling exponents (0 < alpha < 2 and 0 < H < 1). The FBM-SBM process is aging in a manner similar to SBM. The velocity autocorrelation function (ACF) of particle increments of FBM-SBM exhibits a dip when the parent FBM process is subdiffusive. Both for sub- and superdiffusive FBM contributions to the FBM-SBM process, the SBM exponent affects the long-time decay exponent of the ACF. Applications of the FBM-SBM-amalgamated process to the analysis of SPT data are discussed. A comparative tabulated overview of recent experimental (mainly SPT) and computational datasets amenable for interpretation in terms of FBM-, SBM-, and FBM-SBM-like models of diffusion culminates the presentation. The statistical aspects of the dynamics of a wide range of biological systems is compared in the table, from nanosized beads in living cells, to chromosomal loci, to water diffusion in the brain, and, finally, to patterns of animal movements.}, language = {en} } @article{DieterichLindemannMoskoppetal.2022, author = {Dieterich, Peter and Lindemann, Otto and Moskopp, Mats Leif and Tauzin, Sebastien and Huttenlocher, Anna and Klages, Rainer and Chechkin, Aleksei V. and Schwab, Albrecht}, title = {Anomalous diffusion and asymmetric tempering memory in neutrophil chemotaxis}, series = {PLoS Computational Biology : a new community journal}, volume = {18}, journal = {PLoS Computational Biology : a new community journal}, number = {5}, publisher = {PLoS}, address = {San Fransisco}, issn = {1553-734X}, doi = {10.1371/journal.pcbi.1010089}, pages = {26}, year = {2022}, abstract = {Neutrophil granulocytes are essential for the first host defense. After leaving the blood circulation they migrate efficiently towards sites of inflammation. They are guided by chemoattractants released from cells within the inflammatory foci. On a cellular level, directional migration is a consequence of cellular front-rear asymmetry which is induced by the concentration gradient of the chemoattractants. The generation and maintenance of this asymmetry, however, is not yet fully understood. Here we analyzed the paths of chemotacting neutrophils with different stochastic models to gain further insight into the underlying mechanisms. Wildtype chemotacting neutrophils show an anomalous superdiffusive behavior. CXCR2 blockade and TRPC6-knockout cause the tempering of temporal correlations and a reduction of chemotaxis. Importantly, such tempering is found both in vitro and in vivo. These findings indicate that the maintenance of anomalous dynamics is crucial for chemotactic behavior and the search efficiency of neutrophils. The motility of neutrophils and their ability to sense and to react to chemoattractants in their environment are of central importance for the innate immunity. Neutrophils are guided towards sites of inflammation following the activation of G-protein coupled chemoattractant receptors such as CXCR2 whose signaling strongly depends on the activity of Ca2+ permeable TRPC6 channels. It is the aim of this study to analyze data sets obtained in vitro (murine neutrophils) and in vivo (zebrafish neutrophils) with a stochastic mathematical model to gain deeper insight into the underlying mechanisms. The model is based on the analysis of trajectories of individual neutrophils. Bayesian data analysis, including the covariances of positions for fractional Brownian motion as well as for exponentially and power-law tempered model variants, allows the estimation of parameters and model selection. Our model-based analysis reveals that wildtype neutrophils show pure superdiffusive fractional Brownian motion. This so-called anomalous dynamics is characterized by temporal long-range correlations for the movement into the direction of the chemotactic CXCL1 gradient. Pure superdiffusion is absent vertically to this gradient. This points to an asymmetric 'memory' of the migratory machinery, which is found both in vitro and in vivo. CXCR2 blockade and TRPC6-knockout cause tempering of temporal correlations in the chemotactic gradient. This can be interpreted as a progressive loss of memory, which leads to a marked reduction of chemotaxis and search efficiency of neutrophils. In summary, our findings indicate that spatially differential regulation of anomalous dynamics appears to play a central role in guiding efficient chemotactic behavior.}, language = {en} } @article{LucenaPerezBazzicalupoPaijmansetal.2022, author = {Lucena-Perez, Mar{\´i}a and Bazzicalupo, Enrico and Paijmans, Johanna and Kleinman-Ruiz, Daniel and Dal{\´e}n, Love and Hofreiter, Michael and Delibes, Miguel and Clavero, Miguel and Godoy, Jos{\´e} A.}, title = {Ancient genome provides insights into the history of Eurasian lynx in Iberia and Western Europe}, series = {Quaternary science reviews : the international multidisciplinary research and review journal}, volume = {285}, journal = {Quaternary science reviews : the international multidisciplinary research and review journal}, publisher = {Elsevier}, address = {Oxford}, issn = {0277-3791}, doi = {10.1016/j.quascirev.2022.107518}, pages = {9}, year = {2022}, abstract = {The Eurasian lynx (Lynx lynx) is one of the most widely distributed felids in the world. However, most of its populations started to decline a few millennia ago. Historical declines have been especially severe in Europe, and particularly in Western Europe, from where the species disappeared in the last few centuries. Here, we analyze the genome of an Eurasian lynx inhabiting the Iberian Peninsula 2500 ya, to gain insights into the phylogeographic position and genetic status of this extinct population. Also, we contextualize previous ancient data in the light of new phylogeographic studies of the species. Our results suggest that the Iberian population is part of an extinct European lineage closely related to the current Carpathian-Baltic lineages. Also, this sample holds the lowest diversity reported for the species so far, and similar to that of the highly endangered Iberian lynx. A combination of historical factors, such as a founder effect while colonizing the peninsula, together with intensified human impacts during the Holocene in the Cantabrian strip, could have led to a genetic impoverishment of the population and precipitated its extinction. Mitogenomic lineages distribution in space and time support the long-term coexistence of several lineages of Eurasian lynx in Western Europe with fluctuating ranges. While mitochondrial sequences related to the lineages currently found in Balkans and Caucasus were predominant during the Pleistocene, those more closely related to the lineage currently distributed in Central Europe prevailed during the Holocene. The use of ancient genomics has proven to be a useful tool to understand the biogeographic pattern of the Eurasian lynx in the past.}, language = {en} } @article{HoffmannMachatschekLendlein2022, author = {Hoffmann, Falk and Machatschek, Rainhard Gabriel and Lendlein, Andreas}, title = {Analytical model and Monte Carlo simulations of polymer degradation with improved chain cut statistics}, series = {Journal of materials research : JMR}, volume = {37}, journal = {Journal of materials research : JMR}, number = {5}, publisher = {Springer}, address = {Heidelberg}, issn = {0884-2914}, doi = {10.1557/s43578-022-00495-4}, pages = {1093 -- 1101}, year = {2022}, abstract = {The degradation of polymers is described by mathematical models based on bond cleavage statistics including the decreasing probability of chain cuts with decreasing average chain length. We derive equations for the degradation of chains under a random chain cut and a chain end cut mechanism, which are compared to existing models. The results are used to predict the influence of internal molecular parameters. It is shown that both chain cut mechanisms lead to a similar shape of the mass or molecular mass loss curve. A characteristic time is derived, which can be used to extract the maximum length of soluble fragments l of the polymer. We show that the complete description is needed to extract the degradation rate constant k from the molecular mass loss curve and that l can be used to design polymers that lose less mechanical stability before entering the mass loss phase.}, language = {en} } @article{TuerkerCottonPilzetal.2022, author = {T{\"u}rker, Elif and Cotton, Fabrice and Pilz, Marco and Weatherill, Graeme}, title = {Analysis of the 2019 Mw 5.8 Silivri earthquake ground motions}, series = {Seismological research letters}, volume = {93}, journal = {Seismological research letters}, number = {2A}, publisher = {Seismological Society of America}, address = {Boulder, Colo.}, issn = {0895-0695}, doi = {10.1785/0220210168}, pages = {693 -- 705}, year = {2022}, abstract = {The main Marmara fault (MMF) extends for 150 km through the Sea of Marmara and forms the only portion of the North Anatolian fault zone that has not ruptured in a large event (Mw >7) for the last 250 yr. Accordingly, this portion is potentially a major source contributing to the seismic hazard of the Istanbul region. On 26 September 2019, a sequence of moderate-sized events started along the MMF only 20 km south of Istanbul and were widely felt by the population. The largest three events, 26 September Mw 5.8 (10:59 UTC), 26 September 2019 Mw 4.1 (11:26 UTC), and 20 January 2020 Mw 4.7 were recorded by numerous strong-motion seismic stations and the resulting ground motions were compared to the predicted means resulting from a set of the most recent ground-motion prediction equations (GMPEs). The estimated residuals were used to investigate the spatial variation of ground motion across the Marmara region. Our results show a strong azimuthal trend in ground-motion residuals, which might indicate systematically repeating directivity effects toward the eastern Marmara region.}, language = {en} } @article{ArkesAbereggArpin2022, author = {Arkes, Hal R. and Aberegg, Scott K. and Arpin, Kevin A.}, title = {Analysis of physicians' probability estimates of a medical outcome based on a sequence of events}, series = {JAMA network open / American Medical Association}, volume = {5}, journal = {JAMA network open / American Medical Association}, number = {6}, publisher = {American Veterinary Medical Association}, address = {Chicago}, issn = {2574-3805}, doi = {10.1001/jamanetworkopen.2022.18804}, pages = {10}, year = {2022}, abstract = {IMPORTANCE The probability of a conjunction of 2 independent events is the product of the probabilities of the 2 components and therefore cannot exceed the probability of either component; violation of this basic law is called the conjunction fallacy. A common medical decision-making scenario involves estimating the probability of a final outcome resulting from a sequence of independent events; however, little is known about physicians' ability to accurately estimate the overall probability of success in these situations. OBJECTIVE To ascertain whether physicians are able to correctly estimate the overall probability of a medical outcome resulting from 2 independent events. DESIGN, SETTING, AND PARTICIPANTS This survey study consisted of 3 separate substudies, in which 215 physicians were asked via internet-based survey to estimate the probability of success of each of 2 components of a diagnostic or prognostic sequence as well as the overall probability of success of the 2-step sequence. Substudy 1 was performed from April 2 to 4, 2021, substudy 2 from November 2 toll, 2021, and substudy 3 from May 13 to 19, 2021. All physicians were board certified or board eligible in the primary specialty germane to the substudy (ie, obstetrics and gynecology for substudies land 3 and pulmonology for substudy 2), were recruited from a commercial survey service, and volunteered to participate in the study. EXPOSURES Case scenarios presented in an online survey. MAIN OUTCOMES AND MEASURES Respondents were asked to provide their demographic information in addition to 3 probability estimates. The first substudy included a scenario describing a brow presentation discovered during labor; the 2 conjuncts were the probabilities that the brow presentation would resolve and that the delivery would be vaginal. The second substudy involved a diagnostic evaluation of an incidentally discovered pulmonary nodule; the 2 conjuncts were the probabilities that the patient had a malignant condition and that a technically successful transthoracic needle biopsy would reveal a malignant condition. The third substudy included a modification of the first substudy in an attempt to debias the conjunction fallacy prevalent in the first substudy. Respondents' own probability estimates of the individual events were used to calculate the mathematically correct conjunctive probability. RESULTS Among 215 respondents, the mean (SD) age was 54.0 (9.5) years; 142 respondents (66.0\%) were male. Data on race and ethnicity were not collected. A total of 168 physicians (78.1\%) estimated the probability of the 2-step sequence to be greater than the probability of at least 1 of the 2 component events. Compared with the product of their 2 estimated components, respondents overestimated the combined probability by 12.8\% (95\% CI, 9.6\%-16.1\%; P < .001) in substudy 1, 19.8\% (95\% Cl, 16.6\%-23.0\%; P < .001) in substudy 2, and 18.0\% (95\% CI, 13.4\%-22.5\%; P < .001) in substudy 3, results that were mathematically incoherent (ie, formally illogical and mathematically incorrect). CONCLUSIONS AND RELEVANCE In this survey study of 215 physicians, respondents consistently overestimated the combined probability of 2 events compared with the probability calculated from their own estimates of the individual events. This biased estimation, consistent with the conjunction fallacy, may have substantial implications for diagnostic and prognostic decision-making.}, language = {en} } @article{KnocheLisecKoch2022, author = {Knoche, Lisa and Lisec, Jan and Koch, Matthias}, title = {Analysis of electrochemical and liver microsomal transformation products of lasalocid by LC/HRMS}, series = {Rapid communications in mass spectrometry : RCM}, volume = {36}, journal = {Rapid communications in mass spectrometry : RCM}, number = {18}, publisher = {Wiley}, address = {New York, NY}, issn = {0951-4198}, doi = {10.1002/rcm.9349}, pages = {10}, year = {2022}, abstract = {Rationale: Lasalocid (LAS), an ionophore, is used in cattle and poultry farming as feed additive for its antibiotic and growth-promoting properties. Literature on transformation products (TP) resulting from LAS degradation is limited. So far, only hydroxylation is found to occur as the metabolic reaction during the LAS degradation. To investigate potential TPs of LAS, we used electrochemistry (EC) and liver microsome (LM) assays to synthesize TPs, which were identified using liquid chromatography high-resolution mass spectrometry (LC/HRMS). Methods: Electrochemically produced TPs were analyzed online by direct coupling of the electrochemical cell to the electrospray ionization (ESI) source of a Sciex Triple-TOF high resolution mass spectrometer. Then, EC-treated LAS solution was collected and analyzed offline using LC/HRMS to confirm stable TPs and improve their annotation with a chemical structure due to informative MS/MS spectra. In a complementary approach, TPs formed by rat and human microsomal incubation were investigated using LC/HRMS. The resulting data were used to investigate LAS modification reactions and elucidate the chemical structure of obtained TPs. Results: The online measurements identified a broad variety of TPs, resulting from modification reactions like (de-)hydrogenation, hydration, methylation, oxidation as well as adduct formation with methanol. We consistently observed different ion complexations of LAS and LAS-TPs (Na+; 2Na(+) K+; NaNH4+; KNH4+). Two stable methylated EC-TPs were found, structurally annotated, and assigned to a likely modification reaction. Using LM incubation, seven TPs were formed, mostly by oxidation/hydroxylation. After the identification of LM-TPs as Na+-complexes, we identified LM-TPs as K+-complexes. Conclusion: We identified and characterized TPs of LAS using EC- and LM-based methods. Moreover, we found different ion complexes of LAS-based TPs. This knowledge, especially the different ion complexes, may help elucidate the metabolic and environmental degradation pathways of LAS.}, language = {en} } @article{UllrichVladovaMarquartetal.2022, author = {Ullrich, Andr{\´e} and Vladova, Gergana and Marquart, Danny and Braun, Andreas and Gronau, Norbert}, title = {An overwiew of benefits and risks in open innovation projects and the influence of intermediary participation, decision-making authority, experience, and position on their perception}, series = {International journal of innovation management : IJIM}, volume = {26}, journal = {International journal of innovation management : IJIM}, number = {02}, publisher = {World Scientific Publ.}, address = {Singapore}, issn = {1363-9196}, doi = {10.1142/S1363919622500128}, pages = {41}, year = {2022}, abstract = {This paper presents an exploratory study investigating the influence of the factors (1) intermediary participation, (2) decision-making authority, (3) position in the enterprise, and (4) experience in open innovation on the perception and assessment of the benefits and risks expected from participating in open innovation projects. For this purpose, an online survey was conducted in Germany, Austria and Switzerland. The result of this paper is an empirical evidence showing whether and how these factors affect the perception of potential benefits and risks expected within the context of open innovation project participation. Furthermore, the identified effects are discussed against the theory. Existing theory regarding the benefits and risks of open innovation is expanded by (1) finding that they are perceived mostly independently of the factors, (2) confirming the practical relevance of benefits and risks, and (3) enabling a finer distinction between their degrees of relevance according to respective contextual specifics.}, language = {en} } @article{Wanckel2022, author = {Wanckel, Camilla}, title = {An ounce of prevention is worth a pound of cure}, series = {Government information quarterly}, volume = {39}, journal = {Government information quarterly}, number = {4}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0740-624X}, doi = {10.1016/j.giq.2022.101705}, pages = {13}, year = {2022}, abstract = {Public sector organizations at all levels of government increasingly rely on Big Data Algorithmic Systems (BDAS) to support decision-making along the entire policy cycle. But while our knowledge on the use of big data continues to grow for government agencies implementing and delivering public services, empirical research on applications for anticipatory policy design is still in its infancy. Based on the concept of policy analytical capacity (PAC), this case study examines the application of BDAS for early crisis detection within the German Federal Government—that is, the German Federal Foreign Office (FFO) and the Federal Ministry of Defence (FMoD). It uses the nested model of PAC to reflect on systemic, organizational, and individual capacity-building from a neoinstitutional perspective and allow for the consideration of embedded institutional contexts. Results from semi-structured interviews indicate that governments seeking to exploit BDAS in policymaking depend on their institutional environment (e.g., through research and data governance infrastructure). However, specific capacity-building strategies may differ according to the departments' institutional framework, with the FMoD relying heavily on subordinate agencies and the FFO creating network-like structures with external researchers. Government capacity-building at the individual and organizational level is similarly affected by long-established institutional structures, roles, and practices within the organization and beyond, making it important to analyze these three levels simultaneously instead of separately.}, language = {en} } @article{TartivelBlockiBrauneetal.2022, author = {Tartivel, Lucile and Blocki, Anna M. and Braune, Steffen and Jung, Friedrich and Behl, Marc and Lendlein, Andreas}, title = {An Inverse shape-memory hydrogel scaffold switching upon cooling in a tissue-tolerated temperature range}, series = {Advanced materials interfaces}, volume = {9}, journal = {Advanced materials interfaces}, number = {6}, publisher = {Wiley}, address = {Hoboken}, issn = {2196-7350}, doi = {10.1002/admi.202101588}, pages = {9}, year = {2022}, abstract = {Tissue reconstruction has an unmet need for soft active scaffolds that enable gentle loading with regeneration-directing bioactive components by soaking up but also provide macroscopic dimensional stability. Here microporous hydrogels capable of an inverse shape-memory effect (iSME) are described, which in contrast to classical shape-memory polymers (SMPs) recover their permanent shape upon cooling. These hydrogels are designed as covalently photo cross-linked polymer networks with oligo(ethylene glycol)-oligo(propylene glycol)-oligo(ethylene glycol) (OEG-OPG-OEG) segments. When heated after deformation, the OEG-OPG-OEG segments form micelles fixing the temporary shape. Upon cooling, the micelles dissociate again, the deformation is reversed and the permanent shape is obtained. Applicability of this iSME is demonstrated by the gentle loading of platelet-rich plasma (PRP) without causing any platelet activation during this process. PRP is highly bioactive and is widely acknowledged for its regenerative effects. Hence, the microporous inverse shape-memory hydrogel (iSMH) with a cooling induced pore-size effect represents a promising candidate scaffold for tissue regeneration for potential usage in minimally invasive surgery applications.}, language = {en} } @article{VencesKoehlerCrottinietal.2022, author = {Vences, Miguel and K{\"o}hler, J{\"o}rn and Crottini, Angelica and Hofreiter, Michael and Hutter, Carl R. and du Preez, Louis and Preick, Michaela and Rakotoarison, Andolalao and Rancilhac, Lo{\"i}s and Raselimanana, Achille P. and Rosa, Gon{\c{c}}alo M. and Scherz, Mark D. and Glaw, Frank}, title = {An integrative taxonomic revision and redefinition of Gephyromantis (Laurentomantis) malagasius based on archival DNA analysis reveals four new mantellid frog species from Madagascar}, series = {Vertebrate zoology}, volume = {72}, journal = {Vertebrate zoology}, publisher = {Senckenberg Gesellschaft f{\"u}r Naturforschung}, address = {Frankfurt am Main}, issn = {1864-5755}, doi = {10.3897/vz.72.e78830}, pages = {271 -- 309}, year = {2022}, abstract = {The subgenus Laurentomantis in the genus Gephyromantis contains some of the least known amphibian species of Madagascar. The six currently valid nominal species are rainforest frogs known from few individuals, hampering a full understanding of the species diversity of the clade. We assembled data on specimens collected during field surveys over the past 30 years and integrated analysis of mitochondrial and nuclear-encoded genes of 88 individuals, a comprehensive bioacoustic analysis, and morphological comparisons to delimit a minimum of nine species-level lineages in the subgenus. To clarify the identity of the species Gephyromantis malagasius, we applied a target-enrichment approach to a sample of the 110 year old holotype of Microphryne malagasia Methuen and Hewitt, 1913 to assign this specimen to a lineage based on a mitochondrial DNA barcode. The holotype clustered unambiguously with specimens previously named G. ventrimaculatus. Consequently we propose to consider Trachymantis malagasia ventrimaculatus Angel, 1935 as a junior synonym of Gephyromantis malagasius. Due to this redefinition of G. malagasius, no scientific name is available for any of the four deep lineages of frogs previously subsumed under this name, all characterized by red color ventrally on the hindlimbs. These are here formally named as Gephyromantis fiharimpe sp. nov., G. matsilo sp. nov., G. oelkrugi sp. nov., and G. portonae sp. nov. The new species are distinguishable from each other by genetic divergences of >4\% uncorrected pairwise distance in a fragment of the 16S rRNA marker and a combination of morphological and bioacoustic characters. Gephyromantis fiharimpe and G. matsilo occur, respectively, at mid-elevations and lower elevations along a wide stretch of Madagascar's eastern rainforest band, while G. oelkrugi and G. portonae appear to be more range-restricted in parts of Madagascar's North East and Northern Central East regions. Open taxonomic questions surround G. horridus, to which we here assign specimens from Montagne d'Ambre and the type locality Nosy Be; and G. ranjomavo, which contains genetically divergent populations from Marojejy, Tsaratanana, and Ampotsidy.}, language = {en} } @article{HeWangHeetal.2022, author = {He, Yushuang and Wang, Feipeng and He, Li and Wang, Qiang and Li, Jian and Qian, Yihua and Gerhard, Reimund and Plath, Ronald}, title = {An insight Into the role of Nano-Alumina on DC Flashover-Resistance and surface charge variation of Epoxy Nanocomposites}, series = {IEEE transactions on dielectrics and electrical insulation}, volume = {29}, journal = {IEEE transactions on dielectrics and electrical insulation}, number = {3}, publisher = {Inst. of Electr. and Electronics Engineers}, address = {Piscataway}, issn = {1070-9878}, doi = {10.1109/TDEI.2022.3173510}, pages = {1022 -- 1029}, year = {2022}, abstract = {The addition of nano-Al2O3 has been shown to enhance the breakdown voltage of epoxy resin, but its flashover results appeared with disputation. This work concentrates on the surface charge variation and dc flashover performance of epoxy resin with nano-Al2O3 doping. The dispersion of nano-Al2O3 in epoxy is characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM). The dc flashover voltages of samples under either positive or negative polarity are measured with a finger-electrode system, and the surface charge variations before and after flashovers were identified from the surface potential mapping. The results evidence that nano-Al2O3 would lead to a 16.9\% voltage drop for the negative flashovers and a 6.8\% drop for positive cases. It is found that one-time flashover clears most of the accumulated surface charges, regardless of positive or negative. As a result, the ground electrode is neighbored by an equipotential zone enclosed with low-density heterocharges. The equipotential zone tends to be broadened after 20 flashovers. The nano-Al2O3 is noticed as beneficial to downsize the equipotential zone due to its capability on charge migration, which is reasonable to maintain flashover voltage at a high level after multiple flashovers. Hence, nano-Al2O3 plays a significant role in improving epoxy with high resistance to multiple flashovers.}, language = {en} } @article{HoanRichterBorsigetal.2022, author = {Hoan, Tran Viet and Richter, Karl-Gerd and Borsig, Nicolas and Bauer, Jonas and Ha, Nguyen Thi and Norra, Stefan}, title = {An improved groundwater model framework for aquifer structures of the quaternary-formed sediment body in the southernmost parts of the Mekong Delta, Vietnam}, series = {Hydrology : open access journal}, volume = {9}, journal = {Hydrology : open access journal}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {2306-5338}, doi = {10.3390/hydrology9040061}, pages = {20}, year = {2022}, abstract = {The Ca Mau peninsula (CMP) is a key economic region in southern Vietnam. In recent decades, the high demand for water has increased the exploitation of groundwater, thus lowering the groundwater level and leading to risks of degradation, depletion, and land subsidence, as well as salinity intrusion in the groundwater of the whole Mekong Delta region. By using a finite element groundwater model with boundary expansion to the sea, we updated the latest data on hydrogeological profiles, groundwater levels, and exploitation. The basic model setup covers seven aquifers and seven aquitards. It is determined that the inflow along the coastline to the mainland is 39\% of the total inflow. The exploitation of the study area in 2019 was 567,364 m(3)/day. The most exploited aquifers are the upper-middle Pleistocene (qp(2-3)) and the middle Pliocene (n(2)(2)), accounting for 63.7\% and 24.6\%, respectively; the least exploited aquifers are the upper Pleistocene and the upper Miocene, accounting for 0.35\% and 0.02\%, respectively. In the deeper aquifers, qp(2-3) and n(2)(2), the change in storage is negative due to the high exploitation rate, leading to a decline in the reserves of these aquifers. These groundwater model results are the calculations of groundwater reserves from the coast to the mainland in the entire system of aquifers in the CMP. This makes groundwater decision managers, stakeholders, and others more efficient in sustainable water resources planning in the CMP and Mekong Delta (MKD).}, language = {en} } @article{HoudebertZass2022, author = {Houdebert, Pierre and Zass, Alexander}, title = {An explicit Dobrushin uniqueness region for Gibbs point processes with repulsive interactions}, series = {Journal of applied probability / Applied Probability Trust}, volume = {59}, journal = {Journal of applied probability / Applied Probability Trust}, number = {2}, publisher = {Cambridge Univ. Press}, address = {Cambridge}, issn = {0021-9002}, doi = {10.1017/jpr.2021.70}, pages = {541 -- 555}, year = {2022}, abstract = {We present a uniqueness result for Gibbs point processes with interactions that come from a non-negative pair potential; in particular, we provide an explicit uniqueness region in terms of activity z and inverse temperature beta. The technique used relies on applying to the continuous setting the classical Dobrushin criterion. We also present a comparison to the two other uniqueness methods of cluster expansion and disagreement percolation, which can also be applied for this type of interaction.}, language = {en} } @article{WarschburgerWortmannGischetal.2022, author = {Warschburger, Petra and Wortmann, Hanna Rosalie and Gisch, Ulrike Alexandra and Baer, Nadja-Raphaela and Schenk, Liane and Anton, Verena and Bergmann, Manuela M.}, title = {An experimental approach to training interoceptive sensitivity}, series = {Nutrition Journal}, volume = {21}, journal = {Nutrition Journal}, publisher = {Springer Nature}, address = {London}, issn = {1475-2891}, doi = {10.1186/s12937-022-00827-4}, pages = {16}, year = {2022}, abstract = {Background Eating in absence of hunger is quite common and often associated with an increased energy intake co-existent with a poorer food choice. Intuitive eating (IE), i.e., eating in accordance with internal hunger and satiety cues, may protect from overeating. IE, however, requires accurate perception and processing of one's own bodily signals, also referred to as interoceptive sensitivity. Training interoceptive sensitivity might therefore be an effective method to promote IE and prevent overeating. As most studies on eating behavior are conducted in younger adults and close social relationships influence health-related behavior, this study focuses on middle-aged and older couples. Methods The present pilot randomized intervention study aims at investigating the feasibility and effectiveness of a 21-day mindfulness-based training program designed to increase interoceptive sensitivity. A total of N = 60 couples participating in the NutriAct Family Study, aged 50-80 years, will be recruited. This randomized-controlled intervention study comprises three measurement points (pre-intervention, post-intervention, 4-week follow-up) and a 21-day training that consists of daily mindfulness-based guided audio exercises (e.g., body scan). A three-arm intervention study design is applied to compare two intervention groups (training together as a couple vs. training alone) with a control group (no training). Each measurement point includes the assessment of self-reported and objective indicators of interoceptive sensitivity (primary outcome), self-reported indicators of intuitive and maladaptive eating (secondary outcomes), and additional variables. A training evaluation applying focus group discussions will be conducted to assess participants' overall acceptance of the training and its feasibility. Discussion By investigating the feasibility and effectiveness of a mindfulness-based training program to increase interoceptive sensitivity, the present study will contribute to a deeper understanding of how to promote healthy eating in older age.}, language = {en} } @article{AndreeIhdeWeskeetal.2022, author = {Andree, Kerstin and Ihde, Sven and Weske, Mathias and Pufahl, Luise}, title = {An exception handling framework for case management}, series = {Software and Systems Modeling}, volume = {21}, journal = {Software and Systems Modeling}, number = {3}, publisher = {Springer}, address = {Heidelberg}, issn = {1619-1366}, doi = {10.1007/s10270-022-00993-3}, pages = {939 -- 962}, year = {2022}, abstract = {In order to achieve their business goals, organizations heavily rely on the operational excellence of their business processes. In traditional scenarios, business processes are usually well-structured, clearly specifying when and how certain tasks have to be executed. Flexible and knowledge-intensive processes are gathering momentum, where a knowledge worker drives the execution of a process case and determines the exact process path at runtime. In the case of an exception, the knowledge worker decides on an appropriate handling. While there is initial work on exception handling in well-structured business processes, exceptions in case management have not been sufficiently researched. This paper proposes an exception handling framework for stage-oriented case management languages, namely Guard Stage Milestone Model, Case Management Model and Notation, and Fragment-based Case Management. The effectiveness of the framework is evaluated with two real-world use cases showing that it covers all relevant exceptions and proposed handling strategies.}, language = {en} } @article{WendtMorriss2022, author = {Wendt, Julia and Morriss, Jayne}, title = {An examination of intolerance of uncertainty and contingency instruction on multiple indices during threat acquisition and extinction training}, series = {International journal of psychophysiology : official journal of the International Organization of Psychophysiology}, volume = {177}, journal = {International journal of psychophysiology : official journal of the International Organization of Psychophysiology}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, issn = {0167-8760}, doi = {10.1016/j.ijpsycho.2022.05.005}, pages = {171 -- 178}, year = {2022}, abstract = {Individuals who score high in self-reported Intolerance of Uncertainty (IU) tend to find uncertainty aversive. Prior research has demonstrated that under uncertainty individuals with high IU display difficulties in updating learned threat associations to safety associations. Importantly, recent research has shown that providing contingency instructions about threat and safety contingencies (i.e. reducing uncertainty) to individuals with high IU promotes the updating of learned threat associations to safety associations. Here we aimed to conceptually replicate IU and contingency instruction-based effects by conducting a secondary analysis of self-reported IU, ratings, skin conductance, and functional magnetic resonance imaging (fMRI) data recorded during uninstructed/instructed blocks of threat acquisition and threat extinction training (n = 48). Generally, no significant associations were observed between self-reported IU and differential responding to learned threat and safety cues for any measure during uninstructed/instructed blocks of threat acquisition and threat extinction training. There was some tentative evidence that higher IU was associated with greater ratings of unpleasantness and arousal to the safety cue after the experiment and greater skin conductance response to the safety cue during extinction generally. Potential explanations for these null effects and directions for future research are discussed.}, language = {en} } @article{Grebenkov2022, author = {Grebenkov, Denis S.}, title = {An encounter-based approach for restricted diffusion with a gradient drift}, series = {Journal of physics : A, Mathematical and theoretical}, volume = {55}, journal = {Journal of physics : A, Mathematical and theoretical}, number = {4}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1751-8113}, doi = {10.1088/1751-8121/ac411a}, pages = {34}, year = {2022}, abstract = {We develop an encounter-based approach for describing restricted diffusion with a gradient drift toward a partially reactive boundary. For this purpose, we introduce an extension of the Dirichlet-to-Neumann operator and use its eigenbasis to derive a spectral decomposition for the full propagator, i.e. the joint probability density function for the particle position and its boundary local time. This is the central quantity that determines various characteristics of diffusion-influenced reactions such as conventional propagators, survival probability, first-passage time distribution, boundary local time distribution, and reaction rate. As an illustration, we investigate the impact of a constant drift onto the boundary local time for restricted diffusion on an interval. More generally, this approach accesses how external forces may influence the statistics of encounters of a diffusing particle with the reactive boundary.}, language = {en} } @article{SmirnovShpritsAllisonetal.2022, author = {Smirnov, Artem and Shprits, Yuri Y. and Allison, Hayley and Aseev, Nikita and Drozdov, Alexander and Kollmann, Peter and Wang, Dedong and Saikin, Anthony}, title = {An empirical model of the equatorial electron pitch angle distributions in earth's outer radiation belt}, series = {Space Weather: the International Journal of Research and Applications}, volume = {20}, journal = {Space Weather: the International Journal of Research and Applications}, number = {9}, publisher = {American Geophysical Union}, address = {Washington, DC}, issn = {1542-7390}, doi = {10.1029/2022SW003053}, pages = {17}, year = {2022}, abstract = {In this study, we present an empirical model of the equatorial electron pitch angle distributions (PADs) in the outer radiation belt based on the full data set collected by the Magnetic Electron Ion Spectrometer (MagEIS) instrument onboard the Van Allen Probes in 2012-2019. The PADs are fitted with a combination of the first, third and fifth sine harmonics. The resulting equation resolves all PAD types found in the outer radiation belt (pancake, flat-top, butterfly and cap PADs) and can be analytically integrated to derive omnidirectional flux. We introduce a two-step modeling procedure that for the first time ensures a continuous dependence on L, magnetic local time and activity, parametrized by the solar wind dynamic pressure. We propose two methods to reconstruct equatorial electron flux using the model. The first approach requires two uni-directional flux observations and is applicable to low-PA data. The second method can be used to reconstruct the full equatorial PADs from a single uni- or omnidirectional measurement at off-equatorial latitudes. The model can be used for converting the long-term data sets of electron fluxes to phase space density in terms of adiabatic invariants, for physics-based modeling in the form of boundary conditions, and for data assimilation purposes.}, language = {en} } @article{MeraTarkhanov2022, author = {Mera, Azal Jaafar Musa and Tarkhanov, Nikolai}, title = {An elliptic equation of finite index in a domain}, series = {Boletin de la Sociedad Matem{\´a}tica Mexicana}, volume = {28}, journal = {Boletin de la Sociedad Matem{\´a}tica Mexicana}, number = {2}, publisher = {Springer International}, address = {New York [u.a.]}, issn = {1405-213X}, doi = {10.1007/s40590-022-00442-7}, pages = {10}, year = {2022}, abstract = {We give an example of first order elliptic equation for a complex-valued function in a plane domain which has a finite number of linearly independent solutions for any right-hand side. No boundary value conditions are thus required.}, language = {en} } @article{HussJuddKoperetal.2022, author = {Huß, Sebastian and Judd, Rika Siedah and Koper, Kaan and Maeda, Hiroshi A. and Nikoloski, Zoran}, title = {An automated workflow that generates atom mappings for large-scale metabolic models and its application to Arabidopsis thaliana}, series = {The plant journal}, volume = {111}, journal = {The plant journal}, number = {5}, publisher = {Wiley-Blackwell}, address = {Oxford [u.a.]}, issn = {0960-7412}, doi = {10.1111/tpj.15903}, pages = {1486 -- 1500}, year = {2022}, abstract = {Quantification of reaction fluxes of metabolic networks can help us understand how the integration of different metabolic pathways determines cellular functions. Yet, intracellular fluxes cannot be measured directly but are estimated with metabolic flux analysis (MFA), which relies on the patterns of isotope labeling of metabolites in the network. The application of MFA also requires a stoichiometric model with atom mappings that are currently not available for the majority of large-scale metabolic network models, particularly of plants. While automated approaches such as the Reaction Decoder Toolkit (RDT) can produce atom mappings for individual reactions, tracing the flow of individual atoms of the entire reactions across a metabolic model remains challenging. Here we establish an automated workflow to obtain reliable atom mappings for large-scale metabolic models by refining the outcome of RDT, and apply the workflow to metabolic models of Arabidopsis thaliana. We demonstrate the accuracy of RDT through a comparative analysis with atom mappings from a large database of biochemical reactions, MetaCyc. We further show the utility of our automated workflow by simulating N-15 isotope enrichment and identifying nitrogen (N)-containing metabolites which show enrichment patterns that are informative for flux estimation in future N-15-MFA studies of A. thaliana. The automated workflow established in this study can be readily expanded to other species for which metabolic models have been established and the resulting atom mappings will facilitate MFA and graph-theoretic structural analyses with large-scale metabolic networks.}, language = {en} }