@misc{YarmanDechtriratBosserdtetal.2015, author = {Yarman, Aysu and Dechtrirat, Decha and Bosserdt, Maria and Jetzschmann, Katharina J. and Gajovic-Eichelmann, Nenad and Scheller, Frieder W.}, title = {Cytochrome c-derived hybrid systems based on moleculary imprinted polymers}, series = {Electroanalysis : an international journal devoted to fundamental and practical aspects of electroanalysis}, volume = {27}, journal = {Electroanalysis : an international journal devoted to fundamental and practical aspects of electroanalysis}, number = {3}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1040-0397}, doi = {10.1002/elan.201400592}, pages = {573 -- 586}, year = {2015}, abstract = {Hybrid architectures which combine a MIP with an immobilized affinity ligand or a biocatalyst sum up the advantages of both components. In this paper, hybrid architectures combining a layer of a molecularly imprinted electropolymer with a mini-enzyme or a self-assembled monolayer will be presented. (i) Microperoxidase-11 (MP-11) catalyzed oxidation of the drug aminopyrine on a product-imprinted sublayer: The peroxide dependent conversion of the analyte aminopyrine takes place in the MP-11 containing layer on top of a product-imprinted electropolymer on the indicator electrode. The hierarchical architecture resulted in the elimination of interfering signals for ascorbic acid and uric acid. An advantage of the new hierarchical structure is the separation of MIP formation by electropolymerization and immobilization of the catalyst. In this way it was for the first time possible to integrate an enzyme with a MIP layer in a sensor configuration. This combination has the potential to be transferred to other enzymes, e.g. P450, opening the way to clinically important analytes. (ii) Epitope-imprinted poly-scopoletin layer for binding of the C-terminal peptide and cytochrome c (Cyt c): The MIP binds both the target peptide and the parent protein almost eight times stronger than the non-imprinted polymer with affinities in the lower micromolar range. Exchange of only one amino acid in the peptide decreases the binding by a factor of five. (iii) MUA-poly-scopoletin MIP for cytochrome c: Cyt c bound to the MIP covered gold electrode exhibits direct electron transfer with a redox potential and rate constant typical for the native protein. The MIP cover layer suppresses the displacement of the target protein by BSA or myoglobin. The combination of protein imprinted polymers with an efficient electron transfer is a new concept for characterizing electroactive proteins such as Cyt c. The competition with other proteins shows that the MIP binds its target Cyt c preferentially and that molecular shape and the charge of protein determine the binding of interfering proteins.}, language = {en} } @misc{WuGlebeBoeker2015, author = {Wu, Lei and Glebe, Ulrich and B{\"o}ker, Alexander}, title = {Surface-initiated controlled radical polymerizations from silica nanoparticles, gold nanocrystals, and bionanoparticles}, series = {Polymer Chemistry}, volume = {6}, journal = {Polymer Chemistry}, number = {29}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1759-9954}, doi = {10.1039/c5py00525f}, pages = {5143 -- 5184}, year = {2015}, abstract = {In recent years, core/shell nanohybrids containing a nanoparticle core and a distinct surrounding shell of polymer brushes have received extensive attention in nanoelectronics, nanophotonics, catalysis, nanopatterning, drug delivery, biosensing, and many others. From the large variety of existing polymerization methods on the one hand and strategies for grafting onto nanoparticle surfaces on the other hand, the combination of grafting-from with controlled radical polymerization (CRP) techniques has turned out to be the best suited for synthesizing these well-defined core/shell nanohybrids and is known as surface-initiated CRP. Most common among these are surface-initiated atom transfer radical polymerization (ATRP), surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization, and surface-initiated nitroxide-mediated polymerization (NMP). This review highlights the state of the art of growing polymers from nanoparticles using surface-initiated CRP techniques. We focus on mechanistic aspects, synthetic procedures, and the formation of complex architectures as well as novel properties. From the vast number of examples of nanoparticle/polymer hybrids formed by surface-initiated CRP techniques, we present nanohybrid formation from the particularly important and most studied silica nanoparticles, gold nanocrystals, and proteins which can be regarded as bionanoparticles.}, language = {en} } @misc{Spahn2015, author = {Spahn, Hannah}, title = {Poetics of character: transatlantic encounters, 1700-1900}, series = {EARLY AMERICAN LITERATURE}, volume = {50}, journal = {EARLY AMERICAN LITERATURE}, number = {2}, publisher = {Univ. of North Carolina Press}, address = {Chapel Hill}, issn = {0012-8163}, pages = {616 -- 621}, year = {2015}, language = {en} } @misc{Demske2015, author = {Demske, Ulrike}, title = {Adverbial Clauses, Main Clause Phenomena, and the composition of the Left Periphery}, series = {Studies in language}, volume = {39}, journal = {Studies in language}, number = {1}, publisher = {Benjamins}, address = {Amsterdam}, issn = {0378-4177}, doi = {10.1075/sl.39.1.09dem}, pages = {235 -- 243}, year = {2015}, language = {en} } @misc{Hasselhoff2015, author = {Hasselhoff, G{\"o}rge K.}, title = {Midrash Unbound. Transformations and Innovations}, series = {Zeitschrift f{\"u}r Religions- und Geistesgeschichte}, volume = {67}, journal = {Zeitschrift f{\"u}r Religions- und Geistesgeschichte}, number = {2}, publisher = {Brill}, address = {Leiden}, issn = {0044-3441}, pages = {205 -- 206}, year = {2015}, language = {de} } @misc{Piper2015, author = {Piper, Ernst}, title = {Alfred Rosenberg. The Diaries of 1934-1944}, series = {Deutsche Zeitschrift f{\"u}r Geschichtswissenschaft}, volume = {63}, journal = {Deutsche Zeitschrift f{\"u}r Geschichtswissenschaft}, number = {7-8}, publisher = {Metropol-Verl.}, address = {Berlin}, issn = {0044-2828}, pages = {705 -- 707}, year = {2015}, language = {de} } @misc{HuetgesFay2015, author = {Huetges, Annett and Fay, Doris}, title = {Gender influences on career development a brief review}, series = {Journal of personnel psychology.}, volume = {14}, journal = {Journal of personnel psychology.}, number = {3}, publisher = {Hogrefe}, address = {G{\"o}ttingen}, issn = {1866-5888}, doi = {10.1027/1866-5888/a000152}, pages = {113 -- 120}, year = {2015}, language = {en} } @misc{Schoeps2015, author = {Schoeps, Julius H.}, title = {Jewish experiences and loyalty conflicts in the first World War}, series = {Zeitschrift f{\"u}r Religions- und Geistesgeschichte}, volume = {67}, journal = {Zeitschrift f{\"u}r Religions- und Geistesgeschichte}, number = {3-4}, publisher = {Brill}, address = {Leiden}, issn = {0044-3441}, pages = {325 -- 326}, year = {2015}, language = {de} } @misc{MartinezFerreirodeAguiarRofes2015, author = {Martinez-Ferreiro, Silvia and de Aguiar, Vania and Rofes, Adria}, title = {Non-fluent aphasia in Ibero-Romance: a review of morphosyntactic deficits}, series = {Aphasiology : an international, interdisciplinary journal}, volume = {29}, journal = {Aphasiology : an international, interdisciplinary journal}, number = {1}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0268-7038}, doi = {10.1080/02687038.2014.958915}, pages = {101 -- 126}, year = {2015}, abstract = {Background: Castilian-Spanish, Catalan, Galician, and European Portuguese are the most widely spoken languages of the Ibero-Romance group. An increasing number of authors have addressed the impact of aphasia on the morphosyntax of these varieties. However, accurate linguistic characterisations are scarce and the different sources of data have not been yet compiled.Aims: To stimulate state-of-the-art research, we provided a comprehensive summary of morphosyntactic aspects of Ibero-Romance and a review of how these are affected in non-fluent aphasia. The topics we dealt with are the use of verb argument structure and morphology, sentential negation and word order, definite articles, personal and reflexive pronouns, passives, topicalised constructions, questions, and relative clauses.Methods \& Procedures: An exhaustive fieldwork and search of PubMed, Web of Science, and Medline records were performed to retrieve studies focused on morphosyntactic issues concerning the Ibero-Romance varieties. A total of 27 studies produced by 46 authors of varying background emerged. We did not review studies of category-specific deficits and aspects related to bilingual aphasia, although we assume that most speakers of Galician and Catalan are bilingual. Studies of spontaneous speech were included when no controlled experimental tasks were available.Outcomes \& Results: The morphosyntactic commonalities of Ibero-Romance have been tackled from different theoretical perspectives. There exist asymmetries in findings which we explain with the use of different tasks (and task complexity) and individual differences between participants.Conclusions: Discourse-linking factors as well as deviations from the canonical pattern are recurrent answers to these asymmetries. A comprehensive theory of impairments in non-fluent aphasia integrating relevant aspects of both structural and processing accounts seems necessary.}, language = {en} } @misc{PiepoliCorraAbreuetal.2015, author = {Piepoli, Massimo F. and Corra, Ugo and Abreu, Ana and Cupples, Margaret and Davos, Costantinos and Doherty, Patrick and Hoefer, Stephan and Garcia-Porrero, Esteban and Rauchi, Bernhard and Vigorito, Carlo and V{\"o}ller, Heinz and Schmid, Jean-Paul}, title = {Challenges in secondary prevention of cardiovascular diseases A review of the current practice}, series = {International journal of cardiology}, volume = {180}, journal = {International journal of cardiology}, publisher = {Elsevier}, address = {Clare}, organization = {European Assoc Cardiovasc Preventi}, issn = {0167-5273}, doi = {10.1016/j.ijcard.2014.11.107}, pages = {114 -- 119}, year = {2015}, abstract = {With the changing demography of populations and increasing prevalence of co-morbidity, frail patients and more complex cardiac conditions, the modern medicine is facing novel challenges leading to rapid innovation where evidence and experiences are lacking. This scenario is also evident in cardiovascular disease prevention, which continuously needs to accommodate its ever changing strategies, settings, and goals. The present paper summarises actual challenges of secondary prevention, and discusses how this intervention should not only be effective but also efficient. By this way the paper tries to bridge the gaps between research and real-world findings and thereby may find ways to improve standard care. (C) 2014 Elsevier Ireland Ltd. All rights reserved.}, language = {en} }