@misc{ReicheKratzHofmannetal.2011, author = {Reiche, J{\"u}rgen and Kratz, Karl and Hofmann, Dieter and Lendlein, Andreas}, title = {Current status of Langmuir monolayer degradation of polymeric biomaterials}, series = {The international journal of artificial organs}, volume = {34}, journal = {The international journal of artificial organs}, number = {2}, publisher = {Wichtig}, address = {Milano}, issn = {0391-3988}, doi = {10.5301/IJAO.2011.6401}, pages = {123 -- 128}, year = {2011}, abstract = {Langmuir monolayer degradation (LMD) experiments with polymers possessing outstanding biomedical application potential yield information regarding the kinetics of their hydrolytic or enzymatic chain scission under well-defined and adjustable degradation conditions. A brief review is given of LMD investigations, including the author's own work on 2-dimensional (2D) polymer systems, providing chain scission data, which are not disturbed by simultaneously occurring transport phenomena, such as water penetration into the sample or transport of scission fragments out of the sample. A knowledge-based approach for the description and simulation of polymer hydrolytic and enzymatic degradation based on a combination of fast LMD experiments and computer simulation of the water penetration is briefly introduced. Finally, the advantages and disadvantages of this approach are discussed.}, language = {en} } @article{KoepfHarderReicheetal.2011, author = {K{\"o}pf, Michael H. and Harder, Heiko and Reiche, J{\"u}rgen and Santer, Svetlana}, title = {Impact of temperature on the LB patterning of DPPC on Mica}, series = {Langmuir}, volume = {27}, journal = {Langmuir}, number = {20}, publisher = {American Chemical Society}, address = {Washington}, issn = {0743-7463}, doi = {10.1021/la202728t}, pages = {12354 -- 12360}, year = {2011}, abstract = {The influence of the subphase temperature on the stripe pattern formation during Langmuir-Blodgett transfer (LB patterning) is investigated in a combined experimental and theoretical study. According to our experiments on the LB transfer of dipalmitoylphosphatidylcholine (DPPC) on planar mica substrates, even small temperature changes between 21.5 and 24.5 degrees C lead to significant changes in the monolayer patterns. For a constant surface pressure and dipper speed, the width of the stripes and the overall spatial period of the patterns increase with increasing subphase temperature. Because the stripe patterns are ascribed to alternating monolayer domains in the liquid-expanded and the liquid-condensed phases, the working regime for the formation of stripes is found to depend strongly on the respective surface pressure-area isotherm. These experimental findings are in accordance with the results of a theoretical investigation based on a model that takes hydrodynamics and the monolayer thermodynamics into account.}, language = {en} }