@article{XieTechritzHaebeletal.2005,
  author    = {Xie, J. and Techritz, S. and Haebel, Sophie and Horn, A. and Neitzel, H. and Klose, J. and Schuelke, M.},
  title     = {A two-dimensional electrophoretic map of human mitochondrial proteins from immortalized lymphoblastoid cell lines: a prerequisite to study mitochondrial disorders in patients},
  issn      = {1615-9853},
  year      = {2005},
  abstract  = {Mitochondrial diseases may be caused by numerous mutations that alter proteins of the respiratory chain and of other metabolic pathways in the mitochondrium. For clinicians this disease group poses a considerable diagnostic challenge due to ambiguous genotype-phenotype relationships. Until now, only 30 \% of the mitochondriopathies can be diagnosed at the molecular level. We therefore need a new diagnostic tool that offers a wide view on the mitochondrial proteins. Here, we present a method to generate a high-resolution, large-gel two-dimensional gel electrophoretic (2-DE) map of a purified fraction of mitochondrial proteins from Epstein-Barr virus-immortalized lymphoblastoid cell line (LCL). LCLs can be easily obtained from patients and control subjects in a routine clinical setting. They often express the biochemical phenotype and can be cultured to high cell numbers, sufficient to gain enough purified material for 2- DE. In total we identified 166 mitochondrial proteins. Thirteen proteins were earlier not known to be of mitochondrial origin. Thirty-nine proteins were associated with human diseases ranging from respiratory chain enzyme deficiencies to disorders of P-oxidation and amino acid metabolism. This 2-DE map is intended to be the first step to diagnose mitochondrial diseases at the proteomic level},
  language  = {en}
}
@article{KehrHaebelBlechschmidtSchneideretal.1999,
  author    = {Kehr, Julia and Haebel, Sophie and Blechschmidt-Schneider, Sabine and Willmitzer, Lothar and Steup, Martin and Fisahn, Joachim},
  title     = {Analysis of phloem protein patterns from different organs of Cucurbita maxima Duch. by matrix-assisted laser desorption/ionization time of flight mass spectroscopy combined with sodium dodecyl sufate-polyacryilamide gel electrophoresis},
  year      = {1999},
  language  = {en}
}
@article{RawelKrollRieseSchneideretal.1998,
  author    = {Rawel, Harshadrai Manilal and Kroll, J{\"u}rgen and Riese-Schneider, Brigitte and Haebel, Sophie},
  title     = {Changes in physico-chemical and enzymatic properties of benzyl isothiocyanate derivatized proteinases},
  year      = {1998},
  language  = {en}
}
@article{BahrkeEinarssonGislasonetal.2003,
  author    = {Bahrke, Sven and Einarsson, Jon M. and Gislason, Johannes and Haebel, Sophie and Peter-Katalinic, Jasna},
  title     = {Characterization of chitooligosaccharides by mass spectrometry},
  isbn      = {82-471-5901-5},
  year      = {2003},
  abstract  = {Heterochitooligosaccharides of DP 6, DP 9, and DP 12 were evaluated using established methods of derivatization and matrix-assisted laser desorption ionization post source decay mass spectrometry.},
  language  = {en}
}
@phdthesis{BahrkeEinarssonGislasonetal.2003,
  author    = {Bahrke, Sven and Einarsson, Jon M. and Gislason, Johannes and Haebel, Sophie and Peter-Katalinic, Jasna and Peter, Martin G.},
  title     = {Characterization of chitooligosaccharides by mass spectrometry},
  isbn      = {82-47-15901-5},
  year      = {2003},
  language  = {en}
}
@article{RitteEckermannHaebeletal.2000,
  author    = {Ritte, Gerhard and Eckermann, Nora and Haebel, Sophie and Lorberth, Ruth and Steup, Martin},
  title     = {Compartmentation of the starch-related R1 protein in higher plants},
  year      = {2000},
  language  = {en}
}
@article{HaebelAlbrechtSparbieretal.1998,
  author    = {Haebel, Sophie and Albrecht, Tanja and Sparbier, Katrin and Walden, Peter and K{\"o}rner, Roman and Steup, Martin},
  title     = {Electrophoresis-related protein modification: alkylation of carboxy residues revealed by mass spectrometry},
  year      = {1998},
  language  = {en}
}
@article{TsukamotoHaebelValencaetal.2008,
  author    = {Tsukamoto, Junko and Haebel, Sophie and Valenca, Gustavo P. and Peter, Martin G. and FRanco, Telma T.},
  title     = {Enzymatic direct synthesis of acrylic acid esters of mono- and disaccharides},
  issn      = {0268-2575},
  year      = {2008},
  abstract  = {Background: There is an increased need to replace materials derived from fossil sources by renewables. Sugar- cane derived carbohydrates are very abundant in Brazil and are the cheapest sugars available in the market, with more than 400 million tons of sugarcane processed in the year 2007. The objective of this work was to study the prepn. of sugar acrylates from free sugars and free acrylic acid, thus avoiding the previous prepn. of protected sugar derivs., such as glycosides, or activated acrylates, such as vinyl acrylate. Results: Lipase catalyzed esterification of three mono- and two disaccharides with acrylic acid, in the presence or absence of mol. sieves was investigated. The reactions were monitored by high-performance liq. chromatog. (HPLC) and the products were analyzed by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry. The main products are mono- and diacrylates, while higher esters are formed as minor products. The highest conversion to sugar acrylates was obsd. for the D-glucose and D- fructose, followed by D-xylose and D-maltose. Mol. sieves had no pronounced effect on the conversion. Conclusions: A feasible method is described to produce and to characterize sugar acrylates, including those contg. more than two acrylate groups. The process for prodn. of these higher esters could potentially be optimized further to produce mols. for crosslinking in acrylate polymn. and other applications. The direct enzymic esterification of free carbohydrates with acrylic acid is unprecedented. [on SciFinder (R)].},
  language  = {en}
}
@article{AsgeirssonHaebelThorsteinssonetal.1998,
  author    = {Asgeirsson, Bjarni and Haebel, Sophie and Thorsteinsson, Leifur and Helgason, Erlendur and Gudmundsson, Kristbj{\"o}rn O. and Gudmundsson, Gunnar and Roepstorff, Peter},
  title     = {Hereditary cystatin C amyloid angiopathy: monitoring the presence of the Leu-68 -> Gln cystatin C variant in cerebrospinal fluids and monocyte cultures by MS},
  year      = {1998},
  language  = {en}
}
@article{StoeckigtHaebel1998,
  author    = {St{\"o}ckigt, Detlef and Haebel, Sophie},
  title     = {Identification of CID fragments from a protonated glutathione conjugate by isotope-specific MS3 experiments in an ion trap},
  year      = {1998},
  language  = {en}
}