@article{KieferKrahlOsthoffetal.2017,
  author    = {Kiefer, Thomas and Krahl, Dorothea and Osthoff, Kathrin and Thuss-Patience, Peter and Bunse, J{\"o}rg and Adam, Ulrich and Jansen, Marc H. and Ott, Rudolf and Pfitzmann, Robert and Pross, Matthias and Kohlmann, Thomas and Daeschlein, Georg and Buhlert, Hermann and V{\"o}ller, Heinz and Hirt, Carsten},
  title     = {Importance of Pancreatic Enzyme Replacement Therapy after Surgery of Cancer of the Esophagus or the Esophagogastric Junction},
  series = {Nutrition and cancer : an international journal},
  volume    = {70},
  journal   = {Nutrition and cancer : an international journal},
  number    = {1},
  publisher = {Routledge, Taylor \& Francis Group},
  address   = {Abingdon},
  issn      = {0163-5581},
  doi       = {10.1080/01635581.2017.1374419},
  pages     = {69 -- 72},
  year      = {2017},
  abstract  = {After surgical treatment of cancer of the esophagus or the esophagogastric junction we observed steatorrhea, which is so far seldom reported. We analyzed all patients treated in our rehabilitation clinic between 2011 and 2014 and focused on the impact of surgery on digestion of fat. Reported steatorrhea was anamnestic, no pancreatic function test was made. Here we show the results from 51 patients. Twenty-three (45\%) of the patients reported steatorrhea. Assuming decreased pancreatic function pancreatic enzyme replacement therapy (PERT) was started or modified during the rehabilitation stay (in the following called STEA(+)). These patients were compared with the patients without steatorrhea and without PERT (STEA(-)). Maximum weight loss between surgery and rehabilitation start was 18 kg in STEA(+) patient and 15.3 kg in STEA(-) patients. STEA(+) patients gained more weight under PERT during the rehabilitation phase (3 wk) than STEA(-) patients without PERT (+1.0 kg vs. -0.3 kg, P = 0.032). We report for the first time, that patients after cancer related esophageal surgery show anamnestic signs of exocrine pancreas insufficiency and need PERT to gain body weight.},
  language  = {en}
}
@article{KieferKrahlHirtetal.2019,
  author    = {Kiefer, Thomas and Krahl, Dorothea and Hirt, Carsten and V{\"o}ller, Heinz and Voelkel, Lorenz and Daeschlein, Georg},
  title     = {Influence of treatment caused impairments on anxiety and depression in patients with cancer of the Esophagus or the Esophagogastric junction},
  series = {Journal of gastrointestinal cancer},
  volume    = {51},
  journal   = {Journal of gastrointestinal cancer},
  number    = {1},
  publisher = {Springer},
  address   = {New York},
  issn      = {1941-6628},
  doi       = {10.1007/s12029-018-00193-7},
  pages     = {30 -- 34},
  year      = {2019},
  abstract  = {Purpose After therapy of cancer of the esophagus or the esophagogastric junction, patients often suffer from anxiety and depression. Some risk factors for elevated anxiety and depression are reported, but the influence of steatorrhea, the frequency of which has only recently been reported, has not yet been investigated. Method Using the Hospital Anxiety and Depression Scale (HADS), we analyzed the correlation of anxiety and depression with steatorrhea, appetite, and weight loss in 72 patients with cancer of the esophagus or of the esophagogastric junction, who were treated at our rehabilitation clinic between January 2011 and December 2014. In addition, effectiveness of psychological interviews was analyzed. Results We have evaluable anxiety questionnaires from 51 patients showing a median anxiety value of 5 (range 0-13). As for the depression, results from evaluable questionnaires of 54 patients also showed a median value of 5 (range 0-15). Increased anxiety and depression values (> 7) were observed in 25.4\% and 37.0\% of the patients respectively. Patients who were admitted with steatorrhea for rehabilitation showed a statistically higher anxiety value (median 6.3 vs. 4.7, p < 0.05), reduced appetite, and a weight loss above 15 kg depicting a correlation to anxiety and depression. Psychological conversations helped lowering the depression but had no influence on anxiety. Conclusions Impairments after cancer treatment, such as steatorrhea, appetite loss, and weight loss, should be interpreted as an alarm signal and should necessitate screening for increased anxiety and depression. Psychological therapy can help improving the extent of the depression.},
  language  = {en}
}
@article{KieferVoellerNothroffetal.2019,
  author    = {Kiefer, Thomas and V{\"o}ller, Heinz and Nothroff, J{\"o}rg and Schikora, Martin and von Podewils, Sebastian and Sicher, Claudia and Bartels-Reinisch, Birgit and Heyne, Karolin and Haase, Hermann and J{\"u}nger, Michael and Daeschlein, Georg},
  title     = {Multiresistente Erreger in der onkologischen und kardiologischen Rehabilitation},
  series = {Die Rehabilitation : Zeitschrift f{\"u}r Praxis und Forschung in der Rehabilitation},
  volume    = {58},
  journal   = {Die Rehabilitation : Zeitschrift f{\"u}r Praxis und Forschung in der Rehabilitation},
  number    = {2},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0034-3536},
  doi       = {10.1055/a-0638-9226},
  pages     = {136 -- 142},
  year      = {2019},
  abstract  = {In der vorliegenden Studie wurde die Pr{\"a}valenz der Besiedlung mit multiresistenten Keimen an 155 Patienten aus der onkologischen und 157 Patienten aus der kardiologischen Rehabilitation mittels mikrobiologischen Screenings untersucht. Dabei zeigten 4,5\% der onkologischen und 4,5\% der kardiologischen Rehabilitationspatienten eine Besiedlung mit multiresistenten Erregern. Am h{\"a}ufigsten wurden 2-MRGN und ESBL (2,9\%) nachgewiesen. Onkologische Rehapatienten zeigten doppelt so hohe Pr{\"a}valenzraten f{\"u}r 3-MRGN im Vergleich zu kardiologischen (2,6 und 1,3\%). Insgesamt zeigen onkologische und kardiologische Rehabilitationspatienten vergleichsweise niedrige Pr{\"a}valenzraten f{\"u}r multiresistente Krankenhauskeime.},
  language  = {de}
}