@misc{FrankRadtkeNienstedtetal.2021,
  author    = {Frank, Ulrike and Radtke, Julia and Nienstedt, Julie Cl{\"a}re and P{\"o}tter-Nerger, Monika and Sch{\"o}nwald, Beate and Buhmann, Carsten and Gerloff, Christian and Niessen, Almut and Fl{\"u}gel, Till and Koseki, Jana-Christiane and Pflug, Christina},
  title     = {Dysphagia screening in Parkinson's Disease},
  series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {5},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-56962},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-569625},
  pages     = {10},
  year      = {2021},
  abstract  = {Background Simple water-swallowing screening tools are not predictive of aspiration and dysphagia in patients with Parkinson's Disease (PD). We investigated the diagnostic accuracy of a multi-texture screening tool, the Gugging Swallowing Screen (GUSS) to identify aspiration and dysphagia/penetration in PD patients compared to flexible endoscopic evaluation of swallowing (FEES). Methods Swallowing function was evaluated in 51 PD participants in clinical 'on-medication' state with the GUSS and a FEES examination according to standardized protocols. Inter-rater reliability and convergent validity were determined and GUSS- and FEES-based diet recommendations were compared. Key Results Inter-rater reliability of GUSS ratings was high (r(s) = 0.8; p < 0.001). Aspiration was identified by the GUSS with a sensitivity of 50\%, and specificity of 51.35\% (PPV 28\%, NPV 73\%, LR+ 1.03, LR- 0.97), dysphagia/penetration was identified with 72.97\% sensitivity and 35.71\% specificity (PPV 75\%, NPV 33.33\%, LR+ 1.14, LR- 0.76). Agreement between GUSS- and FEES-based diet recommendations was low (r(s) = 0.12, p = 0.42) with consistent NPO (Nil per Os) allocation by GUSS and FEES in only one participant. Conclusions and Inferences The multi-texture screening tool GUSS in its current form, although applicable with good inter-rater reliability, does not detect aspiration in PD patients with acceptable accuracy. Modifications of the GUSS parameters "coughing," "voice change" and "delayed swallowing" might enhance validity. The GUSS' diet recommendations overestimate the need for oral intake restriction in PD patients and should be verified by instrumental swallowing examination.},
  language  = {en}
}
@article{MuellerBeerFrank2022,
  author    = {M{\"u}ller, Nina and Beer, Carola de and Frank, Ulrike},
  title     = {Ist die therapeutische Mundpflege bei Dysphagiepatient*innen verschwendete Zeit?},
  series = {Sprache, Stimme, Geh{\"o}r : Zeitschrift f{\"u}r Kommunikationsst{\"o}rungen},
  volume    = {46},
  journal   = {Sprache, Stimme, Geh{\"o}r : Zeitschrift f{\"u}r Kommunikationsst{\"o}rungen},
  number    = {03},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0342-0477},
  doi       = {10.1055/a-1714-1587},
  pages     = {150 -- 155},
  year      = {2022},
  abstract  = {Aspirationspneumonien sind eine h{\"a}ufige Todesursache bei Dysphagiepatient*innen. In diesem Beitrag wird durch die Evaluation relevanter Studien die Frage untersucht, ob die therapeutische Mundpflege bei Dysphagiepatient*innen zur Verringerung des Pneumonierisikos beitragen kann. Zudem wird auf dieser Grundlage eine Handlungsempfehlung f{\"u}r die Umsetzung der Mundpflege entwickelt. Die ausgew{\"a}hlten Studien zeigen, dass die Mundpflege einen positiven Effekt auf das Pneumonie-Risiko von Dysphagiepatient*innen hat. Sie sollte auf den Grunds{\"a}tzen Einfachheit, Sicherheit, Arbeitskr{\"a}fteentlastung, Wirksamkeit, Universalit{\"a}t, Wirtschaftlichkeit und vollst{\"a}ndige Mundpflege aller Teile der Mundh{\"o}hle beruhen und nimmt weniger als f{\"u}nf Minuten t{\"a}glich ein. Sie bereitet durch die taktile Stimulation auf die anschließende Dysphagie-Therapie vor und ist somit sinnvoll investierte Therapiezeit.},
  language  = {de}
}
@article{SchlickeweiNienstedtFranketal.2021,
  author    = {Schlickewei, Ole and Nienstedt, Julie Cl{\"a}re and Frank, Ulrike and Fr{\"u}ndt, Odette and P{\"o}tter-Nerger, Monika and Gerloff, Christian and Buhmann, Carsten and M{\"u}ller, Frank and Lezius, Susanne and Koseki, Jana-Christiane and Pflug, Christina},
  title     = {The ability of the eating assessment tool‑10 to detect penetration and aspiration in Parkinson's disease},
  series = {European archives of oto-rhino-laryngology and head \& neck},
  volume    = {278},
  journal   = {European archives of oto-rhino-laryngology and head \& neck},
  number    = {5},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0937-4477},
  doi       = {10.1007/s00405-020-06377-x},
  pages     = {1661 -- 1668},
  year      = {2021},
  abstract  = {Purpose: Dysphagia is common in patients with Parkinson's disease (PD) and often leads to pneumonia, malnutrition, and reduced quality of life. This study investigates the ability of the Eating Assessment Tool-10 (EAT-10), an established, easy self-administered screening tool, to detect aspiration in PD patients. This study aims to validate the ability of the EAT-10 to detect FEES-proven aspiration in patients with PD. Methods: In a controlled prospective cross-sectional study, a total of 50 PD patients completed the EAT-10 and, subsequently, were examined by Flexible Endoscopic Evaluation of Swallowing (FEES) to determine the swallowing status. The results were rated through the Penetration-Aspiration Scale (PAS) and data were analyzed retrospectively. Results: PAS and EAT-10 did not correlate significantly. Selected items of the EAT-10 could not predict aspiration or residues. 19 (38\%) out of 50 patients with either penetration or aspiration were not detected by the EAT-10. The diagnostic accuracy was established at only a sufficient level (AUC 0.65). An optimal cut-off value of >= 6 presented a sensitivity of 58\% and specificity of 82\%. Conclusions: The EAT-10 is not suited for the detection of penetration and aspiration in PD patients. Therefore, it cannot be used as a screening method in this patient population. There is still a need for a valid, simple, and efficient screening tool to assist physicians in their daily diagnostics and to avoid clinical complications.},
  language  = {en}
}
@article{FrankFrank2022,
  author    = {Frank, Ulrike and Frank, Katrin},
  title     = {COVID-19},
  series = {Der Nervenarzt : Organ der Deutschen Gesellschaft f{\"u}r Psychiatrie, Psychotherapie und Nervenheilkunde ; Mitteilungsblatt der Deutschen Gesellschaft f{\"u}r Neurologie},
  volume    = {93},
  journal   = {Der Nervenarzt : Organ der Deutschen Gesellschaft f{\"u}r Psychiatrie, Psychotherapie und Nervenheilkunde ; Mitteilungsblatt der Deutschen Gesellschaft f{\"u}r Neurologie},
  number    = {2},
  publisher = {Springer},
  address   = {New York},
  issn      = {0028-2804},
  doi       = {10.1007/s00115-021-01162-5},
  pages     = {167 -- 174},
  year      = {2022},
  abstract  = {Eine COVID-19-Erkrankung kann zu schweren Krankheitsverl{\"a}ufen mit multiplen Organbeteiligungen und respiratorischen und neurologischen Funktionseinschr{\"a}nkungen f{\"u}hren. Schluckst{\"o}rungen (Dysphagien) k{\"o}nnen in dieser Patientengruppe durch prim{\"a}re Sch{\"a}digungen des zentralen und peripheren neuronalen Netzwerkes der Schluckfunktion entstehen, aber auch bedingt durch die h{\"a}ufig l{\"a}ngere intensivmedizinische Behandlung und Beatmung. Erste klinische Befunde zeigen persistierende Dysphagien im Rahmen des Post-COVID-Syndroms („Long-COVID"), sodass die Patienten auch l{\"a}ngerfristige Maßnahmen zur Rehabilitation einer sicheren und suffizienten oralen Nahrungsaufnahme ben{\"o}tigen. Daher sollte in die Behandlung von COVID-19-Patienten ein strukturiertes erkrankungsspezifisches Monitoring in Bezug auf Dysphagiesymptome integriert werden, und atemtherapeutische Maßnahmen zur Regulation von Husteneffektivit{\"a}t und Atem-Schluck-Koordination sollten auch bei diesen Patienten essenzieller Bestandteil des Dysphagiemanagements sein. Herausforderungen ergeben sich dabei einerseits durch die erforderlichen Anpassungen etablierter Behandlungsstandards an den Infektionsschutz. Zudem m{\"u}ssen Auswahl und Durchf{\"u}hrungsintensit{\"a}t therapeutischer Maßnahmen an die Kapazit{\"a}ten und die spezifische Pathophysiologie der COVID-19- und Long-COVID-Patienten angepasst werden, um weitere funktionelle Verschlechterungen zu vermindern.},
  language  = {de}
}
@article{FrankRadtkeNienstedtetal.2021,
  author    = {Frank, Ulrike and Radtke, Julia and Nienstedt, Julie Cl{\"a}re and P{\"o}tter-Nerger, Monika and Sch{\"o}nwald, Beate and Buhmann, Carsten and Gerloff, Christian and Niessen, Almut and Fl{\"u}gel, Till and Koseki, Jana-Christiane and Pflug, Christina},
  title     = {Dysphagia screening in Parkinson's Disease},
  series = {Neurogastroenterology and motility},
  volume    = {33},
  journal   = {Neurogastroenterology and motility},
  number    = {5},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1350-1925},
  doi       = {10.1111/nmo.14034},
  pages     = {8},
  year      = {2021},
  abstract  = {Background Simple water-swallowing screening tools are not predictive of aspiration and dysphagia in patients with Parkinson's Disease (PD). We investigated the diagnostic accuracy of a multi-texture screening tool, the Gugging Swallowing Screen (GUSS) to identify aspiration and dysphagia/penetration in PD patients compared to flexible endoscopic evaluation of swallowing (FEES). Methods Swallowing function was evaluated in 51 PD participants in clinical 'on-medication' state with the GUSS and a FEES examination according to standardized protocols. Inter-rater reliability and convergent validity were determined and GUSS- and FEES-based diet recommendations were compared. Key Results Inter-rater reliability of GUSS ratings was high (r(s) = 0.8; p < 0.001). Aspiration was identified by the GUSS with a sensitivity of 50\%, and specificity of 51.35\% (PPV 28\%, NPV 73\%, LR+ 1.03, LR- 0.97), dysphagia/penetration was identified with 72.97\% sensitivity and 35.71\% specificity (PPV 75\%, NPV 33.33\%, LR+ 1.14, LR- 0.76). Agreement between GUSS- and FEES-based diet recommendations was low (r(s) = 0.12, p = 0.42) with consistent NPO (Nil per Os) allocation by GUSS and FEES in only one participant. Conclusions and Inferences The multi-texture screening tool GUSS in its current form, although applicable with good inter-rater reliability, does not detect aspiration in PD patients with acceptable accuracy. Modifications of the GUSS parameters "coughing," "voice change" and "delayed swallowing" might enhance validity. The GUSS' diet recommendations overestimate the need for oral intake restriction in PD patients and should be verified by instrumental swallowing examination.},
  language  = {en}
}
@article{FrankFrank2022,
  author    = {Frank, Ulrike and Frank, Katrin},
  title     = {Teamwork is it!},
  series = {Spektrum Patholinguistik 15},
  journal   = {Spektrum Patholinguistik 15},
  number    = {15},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-542-2},
  issn      = {1866-9433},
  doi       = {10.25932/publishup-57213},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-572134},
  pages     = {1 -- 19},
  year      = {2022},
  language  = {de}
}
@misc{FrankFrankMohretal.2022,
  author    = {Frank, Ulrike and Frank, Katrin and Mohr, Bettina and Kurtenbach, Stephanie and Khader-Lindholz, Aischa and Sallat, Stephan and Wagner, Lilli and D{\"u}ring, Sarah and Lubitz, Anika and Schnelle, Kirsten and Klitsch, Julia and Netzebandt, Jonka and Fritsche, Tom and Uhlemann, Charlotte and Wartenburger, Isabell and Hilton, Matt and Neitzel, Isabel and Schmidt, Johanna and Eikerling, Maren and Cholin, Joana and Menze, Clara and Stadie, Nicole and Schmitz-Antonischki, Dorit and Heide, Judith and Plath, Almut and Corsten, Sabine and Hoffmann, Marie and Leinweber, Juliane and Spelter, Bianca and Karstens, Sven},
  title     = {Spektrum Patholinguistik Band 15. Schwerpunktthema: Interdisziplin{\"a}r behandeln - Multiprofessionelle Zusammenarbeit in der Sprachtherapie},
  series = {Spektrum Patholinguistik},
  journal   = {Spektrum Patholinguistik},
  number    = {15},
  editor    = {Tan, Sarah and D{\"u}ring, Sarah and Wilde, Alina and Wunderlich, Hanna and Fritzsche, Tom},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-542-2},
  issn      = {1866-9433},
  doi       = {10.25932/publishup-55820},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-558206},
  pages     = {vii, 180},
  year      = {2022},
  abstract  = {Das 15. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Interdisziplin{\"a}r (be-)handeln - Multiprofessionelle Zusammenarbeit in der Sprachtherapie« fand am 20.11.2021 als Online-Veranstaltung statt. Das Herbsttreffen wird seit 2007 j{\"a}hrlich vom Verband f{\"u}r Patholinguistik e.V. (vpl), seit 2021 vom Deutschen Bundesverband f{\"u}r akademische Sprachtherapie und Logop{\"a}die (dbs) in Kooperation mit der Universit{\"a}t Potsdam durchgef{\"u}hrt. Der vorliegende Tagungsband beinhaltet die Vortr{\"a}ge zum Schwerpunktthema und Informationen aus der Podiumsdiskussion sowie die Posterpr{\"a}sentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.},
  language  = {de}
}
@article{HuckabeeMcIntoshFulleretal.2018,
  author    = {Huckabee, Maggie-Lee and McIntosh, Theresa and Fuller, Laura and Curry, Morgan and Thomas, Paige and Walshe, Margaret and McCague, Ellen and Battel, Irene and Nogueira, Dalia and Frank, Ulrike and van den Engel-Hoek, Lenie and Sella-Weiss, Oshrat},
  title     = {The test of masticating and swallowing solids (TOMASS)},
  series = {International Journal of language \& communicaton disorders},
  volume    = {53},
  journal   = {International Journal of language \& communicaton disorders},
  number    = {1},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1368-2822},
  doi       = {10.1111/1460-6984.12332},
  pages     = {144 -- 156},
  year      = {2018},
  abstract  = {BackgroundClinical swallowing assessment is largely limited to qualitative assessment of behavioural observations. There are limited quantitative data that can be compared with a healthy population for identification of impairment. The Test of Masticating and Swallowing Solids (TOMASS) was developed as a quantitative assessment of solid bolus ingestion. AimsThis research programme investigated test development indices and established normative data for the TOMASS to support translation to clinical dysphagia assessment. Conclusions \& ImplicationsThe TOMASS is presented as a valid, reliable and broadly normed clinical assessment of solid bolus ingestion. Clinical application may help identify dysphagic patients at bedside and provide a non-invasive, but sensitive, measure of functional change in swallowing.},
  language  = {en}
}
@article{FrankvandenEngelHoekNogueiraetal.2018,
  author    = {Frank, Ulrike and van den Engel-Hoek, Lenie and Nogueira, Dalia and Schindler, Antonio and Adams, Sasha and Curry, Morgan and Huckabee, Maggie-Lee},
  title     = {International standardisation of the test of masticating and swallowing solids in children},
  series = {Journal of oral rehabilitation},
  volume    = {46},
  journal   = {Journal of oral rehabilitation},
  number    = {2},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {0305-182X},
  doi       = {10.1111/joor.12728},
  pages     = {161 -- 169},
  year      = {2018},
  abstract  = {The Test of Masticating and Swallowing Solids (TOMASS) is a validated assessment tool measuring the efficiency of solid bolus intake by four quantitative parameters: discrete bites, masticatory cycles, swallows and time to ingest a single cracker. A normative database for adults (20-80+ years) has previously been established. The objective of this study was to investigate the applicability and reliability of the TOMASS in children and adolescents (TOMASS-C) and to establish the normative database for this younger population. We collected data from 638 participants (male: 311, female: 327) in five age groups (4-18 years) with five different but very similar test crackers in four countries. Significant effects of bolus type (cracker), age group and gender on the TOMASS parameters were identified, requiring stratification of the TOMASS-C database by these variables. Intra-rater reliability was excellent (ICC > 0.94) for all parameters; inter-rater reliability was moderate for "number of swallows" (ICC = 0.54), good for "bites" (ICC = 0.78) and "time" (ICC = 0.82), and excellent for "masticatory cycles" (ICC = 0.96). The "Test of Masticating and Swallowing Solids in Children (TOMASS-C)" was identified to be a reliable diagnostic tool for the comprehensive measurement of discrete oral stage components of solid bolus ingestion, standardised by a large normative database that covers age groups from preschoolers to young adults. While differences between gender groups were less pronounced than in the adult population, previous results relating to changes in masticatory and swallowing as a function of age are confirmed by our data.},
  language  = {en}
}
@article{GaeckleDomahsKartmannetal.2019,
  author    = {Gaeckle, Maren and Domahs, Frank and Kartmann, Angelika and Tomandl, Bernd and Frank, Ulrike},
  title     = {Predictors of Penetration-Aspiration in Parkinson's Disease Patients With Dysphagia},
  series = {Annals of Otology, Rhinology and Laryngology},
  volume    = {128},
  journal   = {Annals of Otology, Rhinology and Laryngology},
  number    = {8},
  publisher = {Sage Publ.},
  address   = {Thousand Oaks},
  issn      = {0003-4894},
  doi       = {10.1177/0003489419841398},
  pages     = {728 -- 735},
  year      = {2019},
  abstract  = {Methods: The data of 89 PD patients with dysphagia who underwent routinely conducted videofluoroscopic studies of swallowing (VFSS) were included in this retrospective study. The occurrence of penetration-aspiration was defined as scores >= 3 on the Penetration-Aspiration Scale (PAS). Four commonly reported signs of dysphagia in PD patients were evaluated as possible predictors. Furthermore, the relationships between the occurrence of penetration-aspiration and liquid bolus volume as well as clinical severity of PD (modified Hoehn and Yahr scale) were examined. Results: Logistic regression showed that a delayed initiation of the pharyngeal swallow (odds ratio [OR] = 7.47, P = .008) and a reduced hyolaryngeal excursion (OR = 5.13, P = .012) were predictors of penetration-aspiration. Moreover, there was a strong, positive correlation between increasing liquid bolus volume and penetration-aspiration (gamma = 0.71, P < .001). No correlation was found between severity of PD and penetration-aspiration (gamma = 0.077, P = .783). Conclusion: Results of the present study allow for a better understanding of penetration-aspiration risk in PD patients. They are useful for treatment planning in order to improve safe oral intake and adequate nutrition.},
  language  = {en}
}