@misc{BanerjeeLipowskySanter2020,
  author    = {Banerjee, Pallavi and Lipowsky, Reinhard and Santer, Mark},
  title     = {Coarse-grained molecular model for the Glycosylphosphatidylinositol anchor with and without protein},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {6},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-52374},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-523742},
  pages     = {17},
  year      = {2020},
  abstract  = {Glycosylphosphatidylinositol (GPI) anchors are a unique class of complex glycolipids that anchor a great variety of proteins to the extracellular leaflet of plasma membranes of eukaryotic cells. These anchors can exist either with or without an attached protein called GPI-anchored protein (GPI-AP) both in vitro and in vivo. Although GPIs are known to participate in a broad range of cellular functions, it is to a large extent unknown how these are related to GPI structure and composition. Their conformational flexibility and microheterogeneity make it difficult to study them experimentally. Simplified atomistic models are amenable to all-atom computer simulations in small lipid bilayer patches but not suitable for studying their partitioning and trafficking in complex and heterogeneous membranes. Here, we present a coarse-grained model of the GPI anchor constructed with a modified version of the MARTINI force field that is suited for modeling carbohydrates, proteins, and lipids in an aqueous environment using MARTINI's polarizable water. The nonbonded interactions for sugars were reparametrized by calculating their partitioning free energies between polar and apolar phases. In addition, sugar-sugar interactions were optimized by adjusting the second virial coefficients of osmotic pressures for solutions of glucose, sucrose, and trehalose to match with experimental data. With respect to the conformational dynamics of GPI-anchored green fluorescent protein, the accessible time scales are now at least an order of magnitude larger than for the all-atom system. This is particularly important for fine-tuning the mutual interactions of lipids, carbohydrates, and amino acids when comparing to experimental results. We discuss the prospective use of the coarse-grained GPI model for studying protein-sorting and trafficking in membrane models.},
  language  = {en}
}
@misc{JungingerKuebelSchacheretal.2013,
  author    = {Junginger, Mathias and K{\"u}bel, Christian and Schacher, Felix H. and M{\"u}ller, Axel H. E. and Taubert, Andreas},
  title     = {Crystal structure and chemical composition of biomimetic calcium phosphate nanofibers},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-95176},
  pages     = {11301 -- 11308},
  year      = {2013},
  abstract  = {Calcium phosphate nanofibers with a diameter of only a few nanometers and a cotton-ball-like aggregate morphology have been reported several times in the literature. Although fiber formation seems reproducible in a variety of conditions, the crystal structure and chemical composition of the fibers have been elusive. Using scanning transmission electron microscopy, low dose electron (nano)diffraction, energy-dispersive X-ray spectroscopy, and energy-filtered transmission electron microscopy, we have assigned crystal structures and chemical compositions to the fibers. Moreover, we demonstrate that the mineralization process yields true polymer/calcium phosphate hybrid materials where the block copolymer template is closely associated with the calcium phosphate.},
  language  = {en}
}
@misc{TheteRojasNeumeyeretal.2013,
  author    = {Thete, Aniket and Rojas, Oscar and Neumeyer, David and Koetz, Joachim and Dujardin, Erik},
  title     = {Ionic liquid-assisted morphosynthesis of gold nanorods using polyethyleneimine-capped seeds},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-95196},
  pages     = {14294 -- 14298},
  year      = {2013},
  abstract  = {Seed-mediated gold nanorods with tunable lengths are prepared using new polyethyleneimine-capped gold nanoparticles synthesized in ionic liquid. The effect of polyethyleneimine and ionic liquid during nanorod growth is investigated and shows a marked effect on their final aspect ratio.},
  language  = {en}
}