@article{BohlkenJacobSchaumetal.2017,
  author    = {Bohlken, Jens and Jacob, Louis and Schaum, Peter and Rapp, Michael A. and Kostev, Karel},
  title     = {Hip fracture risk in patients with dementia in German primary care practices},
  series = {Dementia},
  volume    = {16},
  journal   = {Dementia},
  publisher = {Sage Publ.},
  address   = {London},
  issn      = {1471-3012},
  doi       = {10.1177/1471301215621854},
  pages     = {853 -- 864},
  year      = {2017},
  abstract  = {The aim was to analyze the risk of hip fracture in German primary care patients with dementia. This study included patients aged 65-90 from 1072 primary care practices who were first diagnosed with dementia between 2010 and 2013. Controls were matched (1:1) to cases for age, sex, and type of health insurance. The primary outcome was the diagnosis of hip fracture during the three-year follow-up period. A total of 53,156 dementia patients and 53,156 controls were included. A total of 5.3\% of patients and 0.7\% of controls displayed hip fracture after three years. Hip fracture occurred more frequently in dementia subjects living in nursing homes than in those living at home (9.2\% versus 4.3\%). Dementia, residence in nursing homes, and osteoporosis were risk factors for fracture development. Antidementia, antipsychotic, and antidepressant drugs generally had no significant impact on hip fracture risk when prescribed for less than six months. Dementia increased hip fracture risk in German primary care practices.},
  language  = {en}
}
@article{JacobRappKostev2017,
  author    = {Jacob, Louis and Rapp, Michael A. and Kostev, Karel},
  title     = {Long-term use of benzodiazepines in older patients in Germany},
  series = {Therapeutic Advances in Psychopharmacology},
  volume    = {7},
  journal   = {Therapeutic Advances in Psychopharmacology},
  number    = {6/7},
  publisher = {Sage Publ.},
  address   = {London},
  issn      = {2045-1253},
  doi       = {10.1177/2045125317696454},
  pages     = {191 -- 200},
  year      = {2017},
  abstract  = {Background: The purpose of this study was to analyze the prevalence of long-term benzodiazepine use in older adults treated in general and neuropsychiatric practices in Germany. Methods: This study included 32,182 patients over the age of 65 years who received benzodiazepine prescriptions for the first time between January 2010 and December 2014 in general and neuropsychiatric practices in Germany. Follow up lasted until July 2016. The main outcome measure was the proportion of patients treated with benzodiazepines for >6 months. Results: The proportion of patients with benzodiazepine therapy for >6 months increased with age (65-70 years: 12.3\%; 71-80 years: 15.5\%; 81-90 years: 23.7\%; >90 years: 31.6\%) but did not differ significantly between men (15.5\%) and women (17.1\%). The proportion of patients who received benzodiazepines for >6 months was higher among those with sleep disorders (21.1\%), depression (20.8\%) and dementia (32.1\%) than among those with anxiety (15.5\%). By contrast, this proportion was lower among people diagnosed with adjustment disorders (7.7\%) and back pain (3.8\%). Conclusion: Overall, long-term use of benzodiazepines is common in older people, particularly in patients over the age of 80 and in those diagnosed with dementia, sleep disorders, or depression.},
  language  = {en}
}