@article{GraefBatsiosMeyer2015,
  author    = {Gr{\"a}f, Ralph and Batsios, Petros and Meyer, Irene},
  title     = {Evolution of centrosomes and the nuclear lamina: Amoebozoan assets},
  series = {European journal of cell biology},
  volume    = {94},
  journal   = {European journal of cell biology},
  number    = {6},
  publisher = {Elsevier},
  address   = {Jena},
  issn      = {0171-9335},
  doi       = {10.1016/j.ejcb.2015.04.004},
  pages     = {249 -- 256},
  year      = {2015},
  abstract  = {The current eukaryotic tree of life groups most eukaryotes into one of five supergroups, the Opisthokonta, Amoebozoa, Archaeplastida, Excavata and SAR (Stramenopile, Alveolata, Rhizaria). Molecular and comparative morphological analyses revealed that the last eukaryotic common ancestor (LECA) already contained a rather sophisticated equipment of organelles including a mitochondrion, an endomembrane system, a nucleus with a lamina, a microtubule-organizing center (MTOC), and a flagellar apparatus. Recent studies of MTOCs, basal bodies/centrioles, and nuclear envelope organization of organisms in different supergroups have clarified our picture of how the nucleus and MTOCs co-evolved from LECA to extant eukaryotes. In this review we summarize these findings with special emphasis on valuable contributions of research on a lamin-like protein, nuclear envelope proteins, and the MTOC in the amoebozoan model organism Dictyostelium discoideum. (C) 2015 Elsevier GmbH. All rights reserved.},
  language  = {en}
}