@misc{GrossiReichardThomassonetal.2017,
  author    = {Grossi, Giuseppe and Reichard, Christoph and Thomasson, Anna and Vakkuri, Jarmo},
  title     = {Editorial},
  series = {Public money \& management : integrating theory and practice in public management},
  volume    = {37},
  journal   = {Public money \& management : integrating theory and practice in public management},
  publisher = {Routledge, Taylor \& Francis Group},
  address   = {Abingdon},
  issn      = {0954-0962},
  doi       = {10.1080/09540962.2017.1344007},
  pages     = {379 -- 386},
  year      = {2017},
  language  = {en}
}
@misc{HassSandmannReich2017,
  author    = {Hass, Roland and Sandmann, Michael and Reich, Oliver},
  title     = {Photonic sensing in highly concentrated biotechnical processes by photon density wave spectroscopy},
  series = {Proceedings SPIE 10323, 25th International Conference on Optical Fiber Sensors},
  volume    = {10323},
  journal   = {Proceedings SPIE 10323, 25th International Conference on Optical Fiber Sensors},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {978-1-5090-4850-2},
  issn      = {0277-786X},
  doi       = {10.1117/12.2263617},
  pages     = {4},
  year      = {2017},
  abstract  = {Photon Density Wave (PDW) spectroscopy is introduced as a new approach for photonic sensing in highly concentrated biotechnical processes. It independently quantifies the absorption and reduced scattering coefficient calibration-free and as a function of time, thus describing the optical properties in the vis/NIR range of the biomaterial during their processing. As examples of industrial relevance, enzymatic milk coagulation, beer mashing, and algae cultivation in photo bioreactors are discussed.},
  language  = {en}
}
@article{Schmidt2017,
  author    = {Schmidt, Marco F.},
  title     = {miRNA Targeting Drugs},
  series = {Drug Target miRNA: Methods and Protocols},
  volume    = {1517},
  journal   = {Drug Target miRNA: Methods and Protocols},
  publisher = {Springer},
  address   = {New York},
  isbn      = {978-1-4939-6563-2},
  issn      = {1064-3745},
  doi       = {10.1007/978-1-4939-6563-2_1},
  pages     = {3 -- 22},
  year      = {2017},
  abstract  = {Only 20 years after the discovery of small non-coding, single-stranded ribonucleic acids, so-called microRNAs (miRNAs), as post-transcriptional gene regulators, the first miRNA-targeting drug Miravirsen for the treatment of hepatitis C has been successfully tested in clinical Phase II trials. Addressing miRNAs as drug targets may enable the cure, or at least the treatment of diseases, which presently seems impossible. However, due to miRNAs' chemical structure, generation of potential drug molecules with necessary pharmacokinetic properties is still challenging and requires a re-thinking of the drug discovery process. Therefore, this chapter highlights the potential of miRNAs as drug targets, discusses the challenges, and tries to give a complete overview of recent strategies in miRNA drug discovery.},
  language  = {en}
}
@article{AtilawDuffyHeydenreichetal.2017,
  author    = {Atilaw, Yoseph and Duffy, Sandra and Heydenreich, Matthias and Muiva-Mutisya, Lois and Avery, Vicky M. and Erdelyi, Mate and Yenesew, Abiy},
  title     = {Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata},
  series = {Molecules},
  volume    = {22},
  journal   = {Molecules},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1420-3049},
  doi       = {10.3390/molecules22020318},
  pages     = {11},
  year      = {2017},
  abstract  = {In our search for new antiplasmodial agents, the CH2Cl2/CH3OH (1:1) extract of the roots of Tephrosia aequilata was investigated, and observed to cause 100\% mortality of the chloroquine-sensitive (3D7) strain of Plasmodium falciparum at a 10 mg/mL concentration. From this extract three new chalconoids, E-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (1, aequichalcone A), Z-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (2, aequichalcone B), 4-ethoxy-3-hydroxypraecansone B (3, aequichalcone C) and a new pterocarpene, 3,4:8,9-dimethylenedioxy-6a,11a-pterocarpene (4), along with seven known compounds were isolated. The purified compounds were characterized by NMR spectroscopic and mass spectrometric analyses. Compound 1 slowly converts into 2 in solution, and thus the latter may have been enriched, or formed, during the extraction and separation process. The isomeric compounds 1 and 2 were both observed in the crude extract. Some of the isolated constituents showed good to moderate antiplasmodial activity against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum.},
  language  = {en}
}
@article{NishinoOkamotoLeimkuehler2017,
  author    = {Nishino, Takeshi and Okamoto, Ken and Leimk{\"u}hler, Silke},
  title     = {Enzymes of the Xanthine Oxidase Family},
  series = {Molybdenum and tungsten enzymes : biochemistry},
  volume    = {5},
  journal   = {Molybdenum and tungsten enzymes : biochemistry},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  isbn      = {978-1-78262-391-5},
  doi       = {10.1039/9781782623915-00192},
  pages     = {192 -- 239},
  year      = {2017},
  abstract  = {Enzymes from the xanthine oxidase (XO) family of molybdenum enzymes are generally, with some exceptions, molybdenum iron-sulfur flavin hydroxylases. Mammalian xanthine oxidoreductase and aldehyde oxidase were among the first enzymes to be studied in detail more than 100 years ago and, surprisingly, they continue to be thoroughly studied in molecular detail with many open and unresolved questions remaining. Enzymes of the XO family are characterized by a molybdenum cofactor (Moco) active site with a MoVIOS(OH) ligand sphere where substrate hydroxylation of either aromatic or aliphatic carbon centers is catalyzed. During the reaction, electrons are transferred to the oxidizing substrate, most commonly O2 or NAD+, which react at the FAD site.},
  language  = {en}
}
@article{LeimkuehlerLemaireIobbiNivol2017,
  author    = {Leimk{\"u}hler, Silke and Lemaire, Olivier N. and Iobbi-Nivol, Chantal},
  title     = {Bacterial Molybdoenzymes},
  series = {Molybdenum and tungsten enzymes : biochemistry},
  volume    = {5},
  journal   = {Molybdenum and tungsten enzymes : biochemistry},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  isbn      = {978-1-78262-391-5},
  doi       = {10.1039/9781782623915-00117},
  pages     = {117 -- 142},
  year      = {2017},
  abstract  = {The biogenesis of molybdoenzymes is a cytoplasmic event requiring both the folded apoenzymes and the matured molybdenum cofactor. The structure and the complexity of the molybdenum cofactor varies in each molybdoenzyme family and consequently different accessory proteins are required for the maturation of the respective enzymes. Thus, for enzymes of both the DMSO reductase and xanthine oxidase families, specific chaperones exist which are dedicated to increase the stability and the folding of specific members of each family. In this review, we describe the role of these chaperones for molybdoenzyme maturation. We present a model which describes step by step the mechanism of the maturation of representative molybdoenzymes from each family.},
  language  = {en}
}
@article{LeimkuehlerMendel2017,
  author    = {Leimk{\"u}hler, Silke and Mendel, Ralf-Rainer},
  title     = {Molybdenum Cofactor Biosynthesis},
  series = {Molybdenum and tungsten enzymes: biochemistry},
  volume    = {5},
  journal   = {Molybdenum and tungsten enzymes: biochemistry},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  isbn      = {978-1-78262-391-5},
  doi       = {10.1039/9781782623915},
  pages     = {100 -- 116},
  year      = {2017},
  abstract  = {The biosynthesis of the molybdenum cofactor (Moco) is highly conserved among all kingdoms of life. In all molybdoenzymes with the exception of nitrogenase, the molybdenum atom is coordinated to a dithiolene group present in the pterin-based 6-alkyl side chain of molybdopterin (MPT). In general, the biosynthesis of Moco can be divided into three steps in eukaryotes, and four steps in bacteria and archaea: (i) the starting point is the formation of the cyclic pyranopterin monophosphate (cPMP) from 5′GTP, (ii) in the second step the two sulfur molecules are inserted into cPMP leading to the formation of MPT, (iii) in the third step the molybdenum atom is inserted into molybdopterin to form Moco and (iv) additional modification of Moco occurs in bacteria and archaea with the attachment of a nucleotide (CMP or GMP) to the phosphate group of MPT, forming the dinucleotide variants of Moco. This review will focus on the biosynthesis of Moco in bacteria, humans and plants.},
  language  = {en}
}
@misc{KuehneMaasWiesenthaletal.2017,
  author    = {K{\"u}hne, Franziska and Maas, Jana and Wiesenthal, Sophia and Weck, Florian},
  title     = {Supervision in der Verhaltenstherapie},
  series = {Zeitschrift f{\"u}r klinische Psychologie und Psychotherapie : Forschung und Praxis},
  volume    = {46},
  journal   = {Zeitschrift f{\"u}r klinische Psychologie und Psychotherapie : Forschung und Praxis},
  number    = {2},
  publisher = {Hogrefe},
  address   = {G{\"o}ttingen},
  issn      = {1616-3443},
  doi       = {10.1026/1616-3443/a000414},
  pages     = {73 -- 82},
  year      = {2017},
  abstract  = {Theoretischer Hintergrund:Supervision spielt eine zentrale Rolle zum Wissens- und Kompetenzerwerb sowie in der Qualit{\"a}tssicherung. Fragestellung:Ziel war es, den aktuellen Forschungsstand zur Supervision im Rahmen der kognitiven Verhaltenstherapie abzubilden, um daraus Schlussfolgerungen f{\"u}r die zuk{\"u}nftige Forschung abzuleiten. Methode:Zur Evidenzsynthese wurde ein Scoping Review durchgef{\"u}hrt, das die Darstellung zentraler Konzepte, aktueller Evidenz und m{\"o}glicher Forschungsbedarfe erm{\"o}glichte. Neben einer systematischen Literaturrecherche wurden Vorw{\"a}rts- und R{\"u}ckw{\"a}rtssuchstrategien eingesetzt. Ergebnisse:Eingeschlossen wurden zw{\"o}lf Publikationen basierend auf zehn empirischen Studien. Alle Studien beschrieben Ausbildungssettings, aber nur wenige untersuchten {\"u}bende Interventionen (z. B. Rollenspiele). H{\"a}ufig wurden Effekte subjektiv erfasst, die methodische Qualit{\"a}t der Begleitstudien variierte. Schlussfolgerungen:Notwendig sind weitere methodisch hochwertige Studien, experimentell orientiert oder in der klinischen Praxis, die die Supervisionsforschung bereichern k{\"o}nnen.},
  language  = {de}
}
@article{SanderEccardHeim2017,
  author    = {Sander, Martha Maria and Eccard, Jana and Heim, Wieland},
  title     = {Flight range estimation of migrant yellow-browed warblers phylloscopus inornatus on the East Asian flyway},
  series = {Bird study : the journal of the British Trust for Ornithology},
  volume    = {64},
  journal   = {Bird study : the journal of the British Trust for Ornithology},
  publisher = {Taylor \& Francis},
  address   = {Abingdon},
  issn      = {0006-3657},
  doi       = {10.1080/00063657.2017.1409696},
  pages     = {569 -- 572},
  year      = {2017},
  abstract  = {Fat loads were quantified for 2125 Yellow-browed Warblers Phylloscopus inornatus trapped at a stop-over site in Far East Russia during autumn migration. Flight ranges of 660-820km were estimated for the fattest individuals, suggesting that they would need to stop for refuelling at least six times to reach their wintering areas in South East Asia.},
  language  = {en}
}
@article{Apelojg2017,
  author    = {Apelojg, Benjamin},
  title     = {Innovationen als Element einer zukunftsweisenden {\"o}konomischen und technischen Bildung},
  series = {Technische Bildung und berufliche Orientierung im Wandel - R{\"u}ckblicke, Einblicke, Ausblicke},
  volume    = {133/134},
  journal   = {Technische Bildung und berufliche Orientierung im Wandel - R{\"u}ckblicke, Einblicke, Ausblicke},
  editor    = {Apelojg, Benjamin and Banse, Gerhard},
  publisher = {Trafo-Verlag},
  address   = {Berlin},
  isbn      = {978-3-86464-156-5},
  pages     = {95 -- 107},
  year      = {2017},
  abstract  = {Innovationen sind wie ein Motor, der unser {\"o}konomisches, soziales und ge-sellschaftliches Leben antreibt und laufend ver{\"a}ndert. Ob in der Medizin-technik, Luft- und Raumfahrt, Energiegewinnung, im Netz oder in der Schule: In allen Bereichen sorgen Innovationen f{\"u}r die stetige Weiterent-wicklung unser Gesellschaft. Bernd Meier hat die Bedeutung von Innova-tionen und innovativem Denken f{\"u}r die technische Bildung und Schule fr{\"u}h erkannt. Mit einer kurzen R{\"u}ckschau auf sein Wirken hinsichtlich der Be-deutung von Innovationen f{\"u}r die technische und {\"o}konomische Bildung soll ein wichtiger Bereich seiner Arbeit gew{\"u}rdigt werden. Zu Beginn wird der Innovationsbegriff allgemein umrissen und dann mit Blick auf Schule pr{\"a}zi-siert. Danach wird dargestellt, welchen Stellenwert die Thematik Innovation und Technologie nicht nur in den Publikationen von Bernd Meier, sondern auch in seinen Lehrkonzeptionen eingenommen hat. Im Anschluss daran wird diskutiert, warum es gerade im Bildungsbereich so schwer ist, innova-tiv zu sein oder dauerhaft Innovationen durchzusetzen.1 Der Beitrag endet mit einem Ausblick, inwiefern Innovationen auch in Zukunft f{\"u}r Schule und das Fach Wirtschaft-Arbeit-Technik (kurz: WAT) eine wichtige Thematik darstellen sollten.},
  language  = {de}
}