@article{Wiese2015,
  author    = {Wiese, Heike},
  title     = {"This migrants' babble is not a German dialect!": The interaction of standard language ideology and 'us'/'them' dichotomies in the public discourse on a multiethnolect},
  series = {Language in society},
  volume    = {44},
  journal   = {Language in society},
  number    = {3},
  publisher = {Cambridge Univ. Press},
  address   = {New York},
  issn      = {0047-4045},
  doi       = {10.1017/S0047404515000226},
  pages     = {341 -- 368},
  year      = {2015},
  abstract  = {This article investigates a public debate in Germany that put a special spotlight on the interaction of standard language ideologies with social dichotomies, centering on the question of whether Kiezdeutsch, a new way of speaking in multilingual urban neighbourhoods, is a legitimate German dialect. Based on a corpus of emails and postings to media websites, I analyse central topoi in this debate and an underlying narrative on language and identity. Central elements of this narrative are claims of cultural elevation and cultural unity for an idealised standard language High German', a view of German dialects as part of a national folk culture, and the construction of an exclusive in-group of German' speakers who own this language and its dialects. The narrative provides a potent conceptual frame for the Othering of Kiezdeutsch and its speakers, and for the projection of social and sometimes racist deliminations onto the linguistic plane.},
  language  = {en}
}
@article{WiebkingNorthoff2015,
  author    = {Wiebking, Christine and Northoff, Georg},
  title     = {Neural activity during interoceptive awareness and its associations with alexithymia-An fMRI study in major depressive disorder and non-psychiatric controls},
  series = {Frontiers in psychology},
  volume    = {6},
  journal   = {Frontiers in psychology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2015.00589},
  pages     = {16},
  year      = {2015},
  abstract  = {Objective: Alexithymia relates to difficulties recognizing and describing emotions. It has been linked to subjectively increased interoceptive awareness (IA) and to psychiatric illnesses such as major depressive disorder (MDD) and somatization. MDD in turn is characterized by aberrant emotion processing and IA on the subjective as well as on the neural level. However, a link between neural activity in response to IA and alexithymic traits in health and depression remains unclear. Methods: A well-established fMRI task was used to investigate neural activity during IA (heartbeat counting) and exteroceptive awareness (tone counting) in non-psychiatric controls (NC) and MDD. Firstly, comparing MDD and NC, a linear relationship between IA-related activity and scores of the Toronto Alexithymia Scale (TAS) was investigated through whole-brain regression. Secondly, NC were divided by median-split of TAS scores into groups showing low (NC-low) or high (NC-high) alexithymia. MDD and NC-high showed equally high TAS scores. Subsequently, IA-related neural activity was compared on a whole-brain level between the three independent samples (MDD, NC-low, NC-high). Results: Whole-brain regressions between MDD and NC revealed neural differences during IA as a function of TAS-DD (subscale difficulty describing feelings) in the supragenual anterior cingulate cortex (sACC; BA 24/32), which were due to negative associations between TAS-DD and IA-related activity in NC. Contrasting NC subgroups after median-split on a whole-brain level, high TAS scores were associated with decreased neural activity during IA in the sACC and increased insula activity. Though having equally high alexithymia scores, NC-high showed increased insula activity during IA compared to MDD, whilst both groups showed decreased activity in the sACC. Conclusions: Within the context of decreased sACC activity during IA in alexithymia (NC-high and MDD), increased insula activity might mirror a compensatory mechanism in NC-high, which is disrupted in MDD.},
  language  = {en}
}
@article{WiebkingNorthoff2015,
  author    = {Wiebking, Christine and Northoff, Georg},
  title     = {Neural activity during interoceptive awareness and its associations with alexithymia},
  series = {Frontiers in psychology},
  volume    = {6},
  journal   = {Frontiers in psychology},
  number    = {589},
  publisher = {Frontiers Research Foundation},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2015.00589},
  year      = {2015},
  abstract  = {Objective: Alexithymia relates to difficulties recognizing and describing emotions. It has been linked to subjectively increased interoceptive awareness (IA) and to psychiatric illnesses such as major depressive disorder (MDD) and somatization. MDD in turn is characterized by aberrant emotion processing and IA on the subjective as well as on the neural level. However, a link between neural activity in response to IA and alexithymic traits in health and depression remains unclear. Methods: A well-established fMRI task was used to investigate neural activity during IA (heartbeat counting) and exteroceptive awareness (tone counting) in non-psychiatric controls (NC) and MDD. Firstly, comparing MDD and NC, a linear relationship between IA-related activity and scores of the Toronto Alexithymia Scale (TAS) was investigated through whole-brain regression. Secondly, NC were divided by median-split of TAS scores into groups showing low (NC-low) or high (NC-high) alexithymia. MDD and NC-high showed equally high TAS scores. Subsequently, IA-related neural activity was compared on a whole-brain level between the three independent samples (MDD, NC-low, NC-high). Results: Whole-brain regressions between MDD and NC revealed neural differences during IA as a function of TAS-DD (subscale difficulty describing feelings) in the supragenual anterior cingulate cortex (sACC; BA 24/32), which were due to negative associations between TAS-DD and IA-related activity in NC. Contrasting NC subgroups after median-split on a whole-brain level, high TAS scores were associated with decreased neural activity during IA in the sACC and increased insula activity. Though having equally high alexithymia scores, NC-high showed increased insula activity during IA compared to MDD, whilst both groups showed decreased activity in the sACC. Conclusions: Within the context of decreased sACC activity during IA in alexithymia (NC-high and MDD), increased insula activity might mirror a compensatory mechanism in NC-high, which is disrupted in MDD.},
  language  = {en}
}
@article{WiebkingdeGreckDuncanetal.2015,
  author    = {Wiebking, Christine and de Greck, Moritz and Duncan, Niall W. and Tempelmann, Claus and Bajbouj, Malek and Northoff, Georg},
  title     = {Interoception in insula subregions as a possible state marker for depression},
  series = {Frontiers in behavioral neuroscience},
  journal   = {Frontiers in behavioral neuroscience},
  number    = {9},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1662-5153},
  doi       = {10.3389/fnbeh.2015.00082},
  pages     = {14},
  year      = {2015},
  abstract  = {Background: Interoceptive awareness (iA), the awareness of stimuli originating inside the body, plays an important role in human emotions and psychopathology. The insula is particularly involved in neural processes underlying iA. However, iA-related neural activity in the insula during the acute state of major depressive disorder (MDD) and in remission from depression has not been explored. Methods: A well-established fMRI paradigm for studying (iA; heartbeat counting) and exteroceptive awareness (eA; tone counting) was used. Study participants formed three independent groups: patients suffering from MDD, patients in remission from MDD or healthy controls. Task-induced neural activity in three functional subdivisions of the insula was compared between these groups. Results: Depressed participants showed neural hypo-responses during iA in anterior insula regions, as compared to both healthy and remitted participants. The right dorsal anterior insula showed the strongest response to iA across all participant groups. In depressed participants there was no differentiation between different stimuli types in this region (i.e., between iA, eA and noTask). Healthy and remitted participants in contrast showed clear activity differences. Conclusions: This is the first study comparing iA and eA-related activity in the insula in depressed participants to that in healthy and remitted individuals. The preliminary results suggest that these groups differ in there being hypo-responses across insula regions in the depressed participants, whilst non-psychiatric participants and patients in remission from MDD show the same neural activity during iA in insula subregions implying a possible state marker for MDD. The lack of activity differences between different stimulus types in the depressed group may account for their symptoms of altered external and internal focus.},
  language  = {en}
}
@article{WiebkingdeGreckDuncanetal.2015,
  author    = {Wiebking, Christine and de Greck, Moritz and Duncan, Niall W. and Tempelmann, Claus and Bajbouj, Malek and Northoff, Georg},
  title     = {Interoception in insula subregions as a possible state marker for depression - an exploratory fMRI study investigating healthy, depressed and remitted participants},
  series = {Frontiers in behavioral neuroscience},
  volume    = {9},
  journal   = {Frontiers in behavioral neuroscience},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1662-5153},
  doi       = {10.3389/fnbeh.2015.00082},
  pages     = {33},
  year      = {2015},
  abstract  = {Background: Interoceptive awareness, the awareness of stimuli originating inside the body, plays an important role in human emotions and psychopathology. The insula is particularly involved in neural processes underlying iA. However, iA-related neural activity in the insula during the acute state of major depressive disorder (MDD) and in remission from depression has not been explored. Methods: A well-established fMRI paradigm for studying interoceptive awareness (iA; heartbeat counting) and exteroceptive awareness (eA; tone counting) was used. Study participants formed three independent groups: patients suffering from MDD, patients in remission from MDD or healthy controls. Task-induced neural activity in three functional subdivisions of the insula was compared between these groups. Results: Depressed participants showed neural hypo-responses during iA in anterior insula regions, as compared to both healthy and remitted participants. The right dorsal anterior insula showed the strongest response to iA across all participant groups. In depressed participants there was no differentiation between different stimuli types in this region (i.e., between iA, eA and noTask). Healthy and remitted participants in contrast showed clear activity differences. Conclusions: This is the first study comparing iA and eA-related activity in the insula in depressed participants to that in healthy and remitted individuals. The preliminary results suggest that these groups differ in there being hypo-responses across insula regions in the depressed participants, whilst healthy participants and patients in remission from MDD show the same neural activity during iA in insula subregions implying a possible state marker for MDD. The lack of activity differences between different stimulus types in the depressed group may account for their symptoms of altered external and internal focus.},
  language  = {en}
}
@article{WichuraJacobsLinetal.2015,
  author    = {Wichura, Henry and Jacobs, Louis L. and Lin, Andrew and Polcyn, Michael J. and Manthi, Fredrick K. and Winkler, Dale A. and Strecker, Manfred and Clemens, Matthew},
  title     = {A 17-My-old whale constrains onset of uplift and climate change in east Africa},
  series = {Proceedings of the National Academy of Sciences of the United States of America},
  volume    = {112},
  journal   = {Proceedings of the National Academy of Sciences of the United States of America},
  number    = {13},
  publisher = {National Acad. of Sciences},
  address   = {Washington},
  issn      = {0027-8424},
  doi       = {10.1073/pnas.1421502112},
  pages     = {3910 -- 3915},
  year      = {2015},
  abstract  = {Timing and magnitude of surface uplift are key to understanding the impact of crustal deformation and topographic growth on atmospheric circulation, environmental conditions, and surface processes. Uplift of the East African Plateau is linked to mantle processes, but paleoaltimetry data are too scarce to constrain plateau evolution and subsequent vertical motions associated with rifting. Here, we assess the paleotopographic implications of a beaked whale fossil (Ziphiidae) from the Turkana region of Kenya found 740 km inland from the present-day coastline of the Indian Ocean at an elevation of 620 m. The specimen is similar to 17 My old and represents the oldest derived beaked whale known, consistent with molecular estimates of the emergence of modern straptoothed whales (Mesoplodon). The whale traveled from the Indian Ocean inland along an eastward-directed drainage system controlled by the Cretaceous Anza Graben and was stranded slightly above sea level. Surface uplift from near sea level coincides with paleoclimatic change from a humid environment to highly variable and much drier conditions, which altered biotic communities and drove evolution in east Africa, including that of primates.},
  language  = {en}
}
@misc{WichaKeesSolmsetal.2015,
  author    = {Wicha, Sebastian G. and Kees, Martin G. and Solms, Alexander Maximilian and Minichmayr, Iris K. and Kratzer, Alexander and Kloft, Charlotte},
  title     = {TDMx: A novel web-based open-access support tool for optimising antimicrobial dosing regimens in clinical routine},
  series = {International journal of antimicrobial agents},
  volume    = {45},
  journal   = {International journal of antimicrobial agents},
  number    = {4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0924-8579},
  doi       = {10.1016/j.ijantimicag.2014.12.010},
  pages     = {442 -- 444},
  year      = {2015},
  language  = {en}
}
@article{WessonMelnickCisternasetal.2015,
  author    = {Wesson, Robert L. and Melnick, Daniel and Cisternas, Marco and Moreno, Marcos and Ely, Lisa L.},
  title     = {Vertical deformation through a complete seismic cycle at Isla Santa Maria, Chile},
  series = {Nature geoscience},
  volume    = {8},
  journal   = {Nature geoscience},
  number    = {7},
  publisher = {Nature Publ. Group},
  address   = {New York},
  issn      = {1752-0894},
  doi       = {10.1038/NGEO2468},
  pages     = {547 -- U157},
  year      = {2015},
  abstract  = {Individual great earthquakes are posited to release the elastic strain energy that has accumulated over centuries by the gradual movement of tectonic plates(1,2). However, knowledge of plate deformation during a complete seismic cycle-two successive great earthquakes and the intervening interseismic period-remains incomplete(3). A complete seismic cycle began in south-central Chile in 1835 with an earthquake of about magnitude 8.5 (refs 4,5) and ended in 2010 with a magnitude 8.8 earthquake(6). During the first earthquake, an uplift of Isla Santa Maria by 2.4 to 3m was documented(4,5). In the second earthquake, the island was uplifted(7) by 1.8 m. Here we use nautical surveys made in 1804, after the earthquake in 1835 and in 1886, together with modern echo sounder surveys and GPS measurements made immediately before and after the 2010 earthquake, to quantify vertical deformation through the complete seismic cycle. We find that in the period between the two earthquakes, Isla Santa Maria subsided by about 1.4 m. We simulate the patterns of vertical deformation with a finite-element model and find that they agree broadly with predictions from elastic rebound theory(2). However, comparison with geomorphic and geologic records of millennial coastline emergence(8,9) reveal that 10-20\% of the vertical uplift could be permanent.},
  language  = {en}
}
@article{WessigMerkelMueller2015,
  author    = {Wessig, Pablo and Merkel, Roswitha and Mueller, Peter},
  title     = {Articulated rods - a novel class of molecular rods based on oligospiroketals (OSK)},
  series = {Beilstein journal of organic chemistry},
  volume    = {11},
  journal   = {Beilstein journal of organic chemistry},
  publisher = {Beilstein-Institut zur F{\"o}rderung der Chemischen Wissenschaften},
  address   = {Frankfurt, Main},
  issn      = {1860-5397},
  doi       = {10.3762/bjoc.11.11},
  pages     = {74 -- 84},
  year      = {2015},
  abstract  = {We developed a new type of molecular rods consisting of two (or more) rigid units linked by a flexible joint. Consequently we called these constructs articulated rods (ARs). The syntheses of ARs were carried out by a flexible and modular approach providing access to a number of compounds with various functionalizations in terminal positions. First applications were presented with pyrene, cinnamoyl and anthracenyl labelled ARs.},
  language  = {en}
}
@article{WessigBudachThuenemann2015,
  author    = {Wessig, Pablo and Budach, Dennis B. and Th{\"u}nemann, Andreas F.},
  title     = {Dendrimers with Oligospiroketal (OSK) Building Blocks: Synthesis and Properties},
  series = {Chemistry - a European journal},
  volume    = {21},
  journal   = {Chemistry - a European journal},
  number    = {29},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0947-6539},
  doi       = {10.1002/chem.201501386},
  pages     = {10466 -- 10471},
  year      = {2015},
  abstract  = {The development of novel dendrimers containing oligospiroketal (OSK) rods as building blocks is described. The linkage between the core unit (CU), branching units (BU), and OSK rods relies on the CuAAC reaction between terminal alkynes and azides. Two different strategies of dendrimer synthesis were investigated and it was found that the convergent approach is clearly superior to the divergent one. SAXS measurements and MD simulations indicate that the obtained dendrimer features a globular structure with very low density. Obviously, the OSK rods stabilize a rather loose mass-fractal structure.},
  language  = {en}
}