@misc{NikoloskivanDongen2011,
  author    = {Nikoloski, Zoran and van Dongen, Joost T.},
  title     = {Modeling alternatives for interpreting the change in oxygen-consumption rates during hypoxic conditions},
  series = {New phytologist : international journal of plant science},
  volume    = {190},
  journal   = {New phytologist : international journal of plant science},
  number    = {2},
  publisher = {Wiley-Blackwell},
  address   = {Malden},
  issn      = {0028-646X},
  doi       = {10.1111/j.1469-8137.2011.03674.x},
  pages     = {273 -- 276},
  year      = {2011},
  language  = {en}
}
@article{AraujoNunesNesiNikoloskietal.2012,
  author    = {Araujo, Wagner L. and Nunes-Nesi, Adriano and Nikoloski, Zoran and Sweetlove, Lee J. and Fernie, Alisdair R.},
  title     = {Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues},
  series = {Plant, cell \& environment : cell physiology, whole-plant physiology, community physiology},
  volume    = {35},
  journal   = {Plant, cell \& environment : cell physiology, whole-plant physiology, community physiology},
  number    = {1},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken},
  issn      = {0140-7791},
  doi       = {10.1111/j.1365-3040.2011.02332.x},
  pages     = {1 -- 21},
  year      = {2012},
  abstract  = {The tricarboxylic acid (TCA) cycle is a crucial component of respiratory metabolism in both photosynthetic and heterotrophic plant organs. All of the major genes of the tomato TCA cycle have been cloned recently, allowing the generation of a suite of transgenic plants in which the majority of the enzymes in the pathway are progressively decreased. Investigations of these plants have provided an almost complete view of the distribution of control in this important pathway. Our studies suggest that citrate synthase, aconitase, isocitrate dehydrogenase, succinyl CoA ligase, succinate dehydrogenase, fumarase and malate dehydrogenase have control coefficients flux for respiration of -0.4, 0.964, -0.123, 0.0008, 0.289, 0.601 and 1.76, respectively; while 2-oxoglutarate dehydrogenase is estimated to have a control coefficient of 0.786 in potato tubers. These results thus indicate that the control of this pathway is distributed among malate dehydrogenase, aconitase, fumarase, succinate dehydrogenase and 2-oxoglutarate dehydrogenase. The unusual distribution of control estimated here is consistent with specific non-cyclic flux mode and cytosolic bypasses that operate in illuminated leaves. These observations are discussed in the context of known regulatory properties of the enzymes and some illustrative examples of how the pathway responds to environmental change are given.},
  language  = {en}
}
@article{JoseClementeMorenoOmranianSaezetal.2019,
  author    = {Jose Clemente-Moreno, Maria and Omranian, Nooshin and Saez, Patricia and Maria Figueroa, Carlos and Del-Saz, Nestor and Elso, Mhartyn and Poblete, Leticia and Orf, Isabel and Cuadros-Inostroza, Alvaro and Cavieres, Lohengrin and Bravo, Leon and Fernie, Alisdair R. and Ribas-Carbo, Miquel and Flexas, Jaume and Nikoloski, Zoran and Brotman, Yariv and Gago, Jorge},
  title     = {Cytochrome respiration pathway and sulphur metabolism sustain stress tolerance to low temperature in the Antarctic species Colobanthus quitensis},
  series = {New phytologist : international journal of plant science},
  volume    = {225},
  journal   = {New phytologist : international journal of plant science},
  number    = {2},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {0028-646X},
  doi       = {10.1111/nph.16167},
  pages     = {754 -- 768},
  year      = {2019},
  abstract  = {Understanding the strategies employed by plant species that live in extreme environments offers the possibility to discover stress tolerance mechanisms. We studied the physiological, antioxidant and metabolic responses to three temperature conditions (4, 15, and 23 degrees C) of Colobanthus quitensis (CQ), one of the only two native vascular species in Antarctica. We also employed Dianthus chinensis (DC), to assess the effects of the treatments in a non-Antarctic species from the same family. Using fused LASSO modelling, we associated physiological and biochemical antioxidant responses with primary metabolism. This approach allowed us to highlight the metabolic pathways driving the response specific to CQ. Low temperature imposed dramatic reductions in photosynthesis (up to 88\%) but not in respiration (sustaining rates of 3.0-4.2 mu mol CO2 m(-2) s(-1)) in CQ, and no change in the physiological stress parameters was found. Its notable antioxidant capacity and mitochondrial cytochrome respiratory activity (20 and two times higher than DC, respectively), which ensure ATP production even at low temperature, was significantly associated with sulphur-containing metabolites and polyamines. Our findings potentially open new biotechnological opportunities regarding the role of antioxidant compounds and respiratory mechanisms associated with sulphur metabolism in stress tolerance strategies to low temperature.},
  language  = {en}
}