@article{MaiWolskiPuciulMalinowskaetal.2018, author = {Mai, Tobias and Wolski, Karol and Puciul-Malinowska, Agnieszka and Kopyshev, Alexey and Gr{\"a}f, Ralph and Bruns, Michael and Zapotoczny, Szczepan and Taubert, Andreas}, title = {Anionic polymer brushes for biomimetic calcium phosphate mineralization}, series = {Polymers}, volume = {10}, journal = {Polymers}, number = {10}, publisher = {MDPI}, address = {Basel}, issn = {2073-4360}, doi = {10.3390/polym10101165}, pages = {17}, year = {2018}, abstract = {This article describes the synthesis of anionic polymer brushes and their mineralization with calcium phosphate. The brushes are based on poly(3-sulfopropyl methacrylate potassium salt) providing a highly charged polymer brush surface. Homogeneous brushes with reproducible thicknesses are obtained via surface-initiated atom transfer radical polymerization. Mineralization with doubly concentrated simulated body fluid yields polymer/inorganic hybrid films containing AB-Type carbonated hydroxyapatite (CHAP), a material resembling the inorganic component of bone. Moreover, growth experiments using Dictyostelium discoideum amoebae demonstrate that the mineral-free and the mineral-containing polymer brushes have a good biocompatibility suggesting their use as biocompatible surfaces in implantology or related fields.}, language = {en} }