@article{GrimbsArnoldKoseskaetal.2011,
  author    = {Grimbs, Sergio and Arnold, Anne and Koseska, Aneta and Kurths, J{\"u}rgen and Selbig, Joachim and Nikoloski, Zoran},
  title     = {Spatiotemporal dynamics of the Calvin cycle multistationarity and symmetry breaking instabilities},
  series = {Biosystems : journal of biological and information processing sciences},
  volume    = {103},
  journal   = {Biosystems : journal of biological and information processing sciences},
  number    = {2},
  publisher = {Elsevier},
  address   = {Oxford},
  issn      = {0303-2647},
  doi       = {10.1016/j.biosystems.2010.10.015},
  pages     = {212 -- 223},
  year      = {2011},
  abstract  = {The possibility of controlling the Calvin cycle has paramount implications for increasing the production of biomass. Multistationarity, as a dynamical feature of systems, is the first obvious candidate whose control could find biotechnological applications. Here we set out to resolve the debate on the multistationarity of the Calvin cycle. Unlike the existing simulation-based studies, our approach is based on a sound mathematical framework, chemical reaction network theory and algebraic geometry, which results in provable results for the investigated model of the Calvin cycle in which we embed a hierarchy of realistic kinetic laws. Our theoretical findings demonstrate that there is a possibility for multistationarity resulting from two sources, homogeneous and inhomogeneous instabilities, which partially settle the debate on multistability of the Calvin cycle. In addition, our tractable analytical treatment of the bifurcation parameters can be employed in the design of validation experiments.},
  language  = {en}
}
@misc{ArnoldNikoloski2011,
  author    = {Arnold, Anne and Nikoloski, Zoran},
  title     = {A quantitative comparison of Calvin-Benson cycle models},
  series = {Trends in plant science},
  volume    = {16},
  journal   = {Trends in plant science},
  number    = {12},
  publisher = {Elsevier},
  address   = {London},
  issn      = {1360-1385},
  doi       = {10.1016/j.tplants.2011.09.004},
  pages     = {676 -- 683},
  year      = {2011},
  abstract  = {The Calvin-Benson cycle (CBC) provides the precursors for biomass synthesis necessary for plant growth. The dynamic behavior and yield of the CBC depend on the environmental conditions and regulation of the cellular state. Accurate quantitative models hold the promise of identifying the key determinants of the tightly regulated CBC function and their effects on the responses in future climates. We provide an integrative analysis of the largest compendium of existing models for photosynthetic processes. Based on the proposed ranking, our framework facilitates the discovery of best-performing models with regard to metabolomics data and of candidates for metabolic engineering.},
  language  = {en}
}