@article{KonigorskiWernickeSlosareketal.2021, author = {Konigorski, Stefan and Wernicke, Sarah and Slosarek, Tamara and Zenner, Alexander Maximilian and Strelow, Nils and Ruether, Darius Ferenc Ruether and Henschel, Florian and Manaswini, Manisha and Pottb{\"a}cker, Fabian and Edelman, Jonathan Antonio and Owoyele, Babajide and Danieletto, Matteo and Golden, Eddye and Zweig, Micol and Nadkarni, Girish N. and B{\"o}ttinger, Erwin}, title = {StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials}, series = {Journal of Medical Internet Research}, volume = {24}, journal = {Journal of Medical Internet Research}, edition = {7}, publisher = {JMIR Publications}, address = {Richmond, Virginia, USA}, issn = {1438-8871}, doi = {10.2196/35884}, pages = {12}, year = {2021}, abstract = {N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.}, language = {en} } @misc{KonigorskiWernickeSlosareketal.2022, author = {Konigorski, Stefan and Wernicke, Sarah and Slosarek, Tamara and Zenner, Alexander M. and Strelow, Nils and Ruether, Darius F. and Henschel, Florian and Manaswini, Manisha and Pottb{\"a}cker, Fabian and Edelman, Jonathan A. and Owoyele, Babajide and Danieletto, Matteo and Golden, Eddye and Zweig, Micol and Nadkarni, Girish N. and B{\"o}ttinger, Erwin}, title = {StudyU: a platform for designing and conducting innovative digital N-of-1 trials}, series = {Journal of medical internet research}, volume = {24}, journal = {Journal of medical internet research}, number = {7}, publisher = {Healthcare World}, address = {Richmond, Va.}, issn = {1439-4456}, doi = {10.2196/35884}, pages = {12}, year = {2022}, abstract = {N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.}, language = {en} } @misc{KonigorskiWernickeSlosareketal.2021, author = {Konigorski, Stefan and Wernicke, Sarah and Slosarek, Tamara and Zenner, Alexander Maximilian and Strelow, Nils and Ruether, Darius Ferenc and Henschel, Florian and Manaswini, Manisha and Pottb{\"a}cker, Fabian and Edelman, Jonathan Antonio and Owoyele, Babajide and Danieletto, Matteo and Golden, Eddye and Zweig, Micol and Nadkarni, Girish N. and B{\"o}ttinger, Erwin}, title = {StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, number = {12}, doi = {10.25932/publishup-58037}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-580370}, pages = {12}, year = {2021}, abstract = {N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.}, language = {en} } @masterthesis{Zolotarenko2020, type = {Bachelor Thesis}, author = {Zolotarenko, Olha}, title = {Visualization approaches for coherence relations}, doi = {10.25932/publishup-51699}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-516997}, school = {Universit{\"a}t Potsdam}, year = {2020}, abstract = {Die hier vorliegende Arbeit stellt einen Versuch dar, den Visualisierungsans{\"a}tzen in dem Feld der annotierten Diskursrelationen nahezukommen und durch Vergleich verschiedener Programmierwerkzeuge eine anforderungsnahe L{\"o}sung zu finden. Als Gegenstand der Forschung wurden Koh{\"a}renzrelationen ausgew{\"a}hlt, welche eine Reihe an Eigenschaften aufweisen, die f{\"u}r viele Visualisierungsmethoden herausfordernd sein k{\"o}nnen. Die Arbeit stellt f{\"u}nf verschiedene Visualisierungsm{\"o}glichkeiten sowohl von der Anwendungs- als auch von der Entwicklungsperspektive vor. Die zun{\"a}chst getesteten einfachen HTML-Ans{\"a}tze sowie das Softwarepaket displaCy zeigen das unzureichende Niveau f{\"u}r die Visualisierungszwecke dieser Arbeit. Die alternative Implementierung mit D3 w{\"u}rde die Voraussetzungen zwar optimal erf{\"u}llen, sprengt aber deutlich den Rahmen des Projektes. Die gew{\"a}hlte Hauptmethode wurde als Single-Web-Anwendung konzipiert und verwendet das Annotationstool brat, welches die meisten definierten Voraussetzungen f{\"u}r die Repr{\"a}sentation der Koh{\"a}renzrelationen erf{\"u}llt. Die Anwendung stellt die im Text annotierten Koh{\"a}renzrelationen graphisch dar und bietet eine Filterfunktion f{\"u}r verschiedene Relationstypen an.}, language = {en} }