@inproceedings{FreudenbergMauersbergerSpringeretal.2013, author = {Freudenberg, Maxi and Mauersberger, Heidi and Springer, Anne and Fotopoulou, Aikaterini and Blaison, Christophe and Hess, Ursula}, title = {A woman's best friend how the presence of dogs reduces Experimentally induced pain}, series = {Psychophysiology : journal of the Society for Psychophysiological Research}, volume = {50}, booktitle = {Psychophysiology : journal of the Society for Psychophysiological Research}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0048-5772}, pages = {S103 -- S103}, year = {2013}, language = {en} } @phdthesis{Schultheiss2014, author = {Schultheiss, Corinna}, title = {Die Bewertung der pharyngalen Schluckphase mittels Bioimpedanz}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-284-1}, issn = {1869-3822}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-69589}, school = {Universit{\"a}t Potsdam}, pages = {XV, 108}, year = {2014}, abstract = {Schlucken ist ein lebensnotwendiger Prozess, dessen Diagnose und Therapie eine enorme Herausforderung bedeutet. Die Erkennung und Beurteilung von Schlucken und Schluckst{\"o}rungen erfordert den Einsatz von technisch aufwendigen Verfahren, wie Videofluoroskopie (VFSS) und fiberoptisch-endoskopische Schluckuntersuchung (FEES), die eine hohe Belastung f{\"u}r die Patienten darstellen. Beide Verfahren werden als Goldstandard in der Diagnostik von Schluckst{\"o}rungen eingesetzt. Die Durchf{\"u}hrung obliegt in der Regel {\"a}rztlichem Personal. Dar{\"u}ber hinaus erfordert die Auswertung des Bildmaterials der Diagnostik eine ausreichend hohe Erfahrung. In der Therapie findet neben den klassischen Therapiemethoden, wie z.B. di{\"a}tetische Modifikationen und Schluckman{\"o}ver, auch zunehmend die funktionelle Elektrostimulation Anwendung. Ziel der vorliegenden Dissertationsschrift ist die Evaluation eines im Verbundprojekt BigDysPro entwickelten Bioimpedanz (BI)- und Elektromyographie (EMG)-Messsystems. Es wurde gepr{\"u}ft, ob sich das BI- und EMG-Messsystem eignet, sowohl in der Diagnostik als auch in der Therapie als eigenst{\"a}ndiges Messsystem und im Rahmen einer Schluckneuroprothese eingesetzt zu werden. In verschiedenen Studien wurden gesunde Probanden f{\"u}r die {\"U}berpr{\"u}fung der Reproduzierbarkeit (Intra-und Interrater-Reliabilit{\"a}t), der Unterscheidbarkeit von Schluck- und Kopfbewegungen und der Beeinflussung der Biosignale (BI, EMG) durch verschiedene Faktoren (Geschlecht der Probanden, Leitf{\"a}higkeit, Konsistenz und Menge der Nahrung) untersucht. Durch zus{\"a}tzliche Untersuchungen mit Patienten wurde einerseits der Einfluss der Elektrodenart gepr{\"u}ft. Andererseits wurden parallel zur BI- und EMG-Messung auch endoskopische (FEES) und radiologische Schluckuntersuchungen (VFSS) durchgef{\"u}hrt, um die Korrelation der Biosignale mit der Bewegung anatomischer Strukturen (VFSS) und mit der Schluckqualit{\"a}t (FEES) zu pr{\"u}fen. Es wurden 31 gesunde Probanden mit 1819 Schlucken und 60 Patienten mit 715 Schlucken untersucht. Die Messkurven zeigten einen typischen, reproduzierbaren Signalverlauf, der mit anatomischen und funktionellen {\"A}nderungen w{\"a}hrend der pharyngalen Schluckphase in der VFSS korrelierte (r > 0,7). Aus dem Bioimpedanzsignal konnten Merkmale extrahiert werden, die mit physiologischen Merkmalen eines Schluckes, wie verz{\"o}gerter laryngealer Verschluss und Kehlkopfhebung, korrelierten und eine Einsch{\"a}tzung der Schluckqualit{\"a}t in {\"U}bereinstimmung mit der FEES erm{\"o}glichten. In den Signalverl{\"a}ufen der Biosignale konnten signifikante Unterschiede zwischen Schluck- und Kopfbewegungen und den Nahrungsmengen und -konsistenzen nachgewiesen werden. Im Gegensatz zur Nahrungsmenge und -konsistenz zeigte die Leitf{\"a}higkeit der zu schluckenden Nahrung, das Geschlecht der Probanden und die Art der Elektroden keinen signifikanten Einfluss auf die Messsignale. Mit den Ergebnissen der Evaluation konnte gezeigt werden, dass mit dem BI- und EMG-Messsystem ein neuartiges und nicht-invasives Verfahren zur Verf{\"u}gung steht, das eine reproduzierbare Darstellung der pharyngalen Schluckphase und ihrer Ver{\"a}nderungen erm{\"o}glicht. Daraus ergeben sich vielseitige Einsatzm{\"o}glichkeiten in der Diagnostik, z.B. Langzeitmessung zur Schluckfrequenz und Einsch{\"a}tzung der Schluckqualit{\"a}t, und in der Therapie, z.B. der Einsatz in einer Schluckneuroprothese oder als Biofeedback zur Darstellung des Schluckes, von Schluckst{\"o}rungen.}, language = {de} } @article{MuellerMartinezValdesStolletal.2018, author = {Mueller, Juliane and Martinez-Valdes, Eduardo Andr{\´e}s and Stoll, Josefine and Mueller, Steffen and Engel, Tilman and Mayer, Frank}, title = {Differences in neuromuscular activity of ankle stabilizing muscles during postural disturbances}, series = {Gait \& posture}, volume = {61}, journal = {Gait \& posture}, publisher = {Elsevier}, address = {Clare}, issn = {0966-6362}, doi = {10.1016/j.gaitpost.2018.01.023}, pages = {226 -- 231}, year = {2018}, abstract = {The purpose was to examine gender differences in ankle stabilizing muscle activation during postural disturbances. Seventeen participants (9 females: 27 +/- 2yrs., 1.69 +/- 0.1 m, 63 +/- 7 kg; 8 males: 29 +/- 2yrs., 1.81 +/- 0.1 m; 83 +/- 7 kg) were included in the study. After familiarization on a split-belt-treadmill, participants walked (1 m/s) while 15 right-sided perturbations were randomly applied 200 ms after initial heel contact. Muscle activity of M. tibialis anterior (TA), peroneus longus (PL) and gastrocnemius medialis (GM) was recorded during unperturbed and perturbed walking. The root mean square (RMS; [\%]) was analyzed within 200 ms after perturbation. Co-activation was quantified as ratio of antagonist (GM)/agonist (TA) EMG-RMS during unperturbed and perturbed walking. Time to onset was calculated (ms). Data were analyzed descriptively (mean +/- SD) followed by three-way-ANOVA (gender/condition/muscle; alpha= 0.05). Perturbed walking elicited higher EMG activity compared to normal walking for TA and PL in both genders (p < 0.000). RMS amplitude gender comparisons revealed an interaction between gender and condition (F = 4.6, p = 0.049) and, a triple interaction among gender, condition and muscle (F = 4.7, p = 0.02). Women presented significantly higher EMG-RMS [\%] PL amplitude than men during perturbed walking (mean difference = 209.6\%, 95\% confidence interval = -367.0 to -52.2\%, p < 0.000). Co-activation showed significant lower values for perturbed compared to normal walking (p < 0.000), without significant gender differences for both walking conditions. GM activated significantly earlier than TA and PL (p < 0.01) without significant differences between the muscle activation onsets of men and women (p = 0.7). The results reflect that activation strategies of the ankle encompassing muscles differ between genders. In provoked stumbling, higher PL EMG activity in women compared to men is present. Future studies should aim to elucidate if this specific behavior has any relationship with ankle injury occurrence between genders.}, language = {en} } @article{MuellerHadzicMugeleetal.2017, author = {M{\"u}ller, Juliane and Hadzic, Miralem and Mugele, Hendrik and Stoll, Josefine and M{\"u}ller, Steffen and Mayer, Frank}, title = {Effect of high-intensity perturbations during core-specific sensorimotor exercises on trunk muscle activation}, series = {Journal of biomechanics}, volume = {70}, journal = {Journal of biomechanics}, publisher = {Elsevier}, address = {Oxford}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2017.12.013}, pages = {212 -- 218}, year = {2017}, abstract = {Core-specific sensorimotor exercises are proven to enhance neuromuscular activity of the trunk. However, the influence of high-intensity perturbations on training efficiency is unclear within this context. Sixteen participants (29 +/- 2 yrs; 175 +/- 8 cm; 69 +/- 13 kg) were prepared with a 12-lead bilateral trunk EMG. Warm-up on a dynamometer was followed by maximum voluntary isometric trunk (flex/ext) contraction (MVC). Next, participants performed four conditions for a one-legged stance with hip abduction on a stable surface (HA) repeated randomly on an unstable surface (HAP), on a stable surface with perturbation (HA + P), and on an unstable surface with perturbation (HAP + P). Afterwards, bird dog (BD) was performed under the same conditions (BD, BDP, BD + P, BDP + P). A foam pad under the foot (HA) or the knee (BD) was used as an unstable surface. Exercises were conducted on a moveable platform. Perturbations (ACC 50 m/sec(2);100 ms duration;10rep.) were randomly applied in the anterior-posterior direction. The root mean square (RMS) normalized to MVC (\%) was calculated (whole movement cycle). Muscles were grouped into ventral right and left (VR;VL), and dorsal right and left (DR;DL). Ventral Dorsal and right-left ratios were calculated (two way repeated-measures ANOVA;alpha = 0,05). Amplitudes of all muscle groups in bird dog were higher compared to hip abduction (p <= 0.0001; Range: BD: 14 +/- 3\% (BD;VR) to 53 +/- 4\%; HA: 7 +/- 2\% (HA;DR) to 16 +/- 4\% (HA;DR)). EMG-RMS showed significant differences (p < 0.001) between conditions and muscle groups per exercise. Interaction effects were only significant for HA (p = 0.02). No significant differences were present in EMG ratios (p > 0.05). Additional high-intensity perturbations during core-specific sensorimotor exercises lead to increased neuromuscular activity and therefore higher exercise intensities. However, the beneficial effects on trunk function remain unclear. Nevertheless, BD is more suitable to address trunk muscles.}, language = {en} } @article{LesinskiPrieskeBordeetal.2018, author = {Lesinski, Melanie and Prieske, Olaf and Borde, Ron and Beurskens, Rainer and Granacher, Urs}, title = {Effects of Different Footwear Properties and Surface Instability on Neuromuscular Activity and Kinematics During Jumping}, series = {Journal of strength and conditioning research : the research journal of the NSCA}, volume = {32}, journal = {Journal of strength and conditioning research : the research journal of the NSCA}, number = {11}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {1064-8011}, doi = {10.1519/JSC.0000000000002556}, pages = {3246 -- 3257}, year = {2018}, abstract = {The purpose of this study was to examine sex-specific effects of different footwear properties vs. barefoot condition during the performance of drop jumps (DJs) on stable and unstable surfaces on measures of jump performance, electromyographic (EMG) activity, and knee joint kinematics. Drop jump performance, EMG activity of lower-extremity muscles, as well as sagittal and frontal knee joint kinematics were tested in 28 healthy male (n = 14) and female (n = 14) physically active sports science students (23 6 2 years) during the performance of DJs on stable and unstable surfaces using different footwear properties (elastic vs. minimal shoes) vs. barefoot condition. Analysis revealed a significantly lower jump height and performance index (Delta 7-12\%; p < 0.001; 2.22 <= d = 2.90) during DJs on unstable compared with stable surfaces. This was accompanied by lower thigh/shank muscle activities (Delta 11-28\%; p < 0.05; 0.99 <= d = 2.16) and knee flexion angles (Delta 5-8\%; p < 0.05; 1.02 <= d = 2.09). Furthermore, knee valgus angles during DJs were significantly lower when wearing shoes compared with barefoot condition (Delta 22-32\%; p < 0.01; 1.38 <= d = 3.31). Sex-specific analyses indicated higher knee flexion angles in females compared with males during DJs, irrespective of the examined surface and footwear conditions (Delta 29\%; p < 0.05; d = 0.92). Finally, hardly any significant footwear-surface interactions were detected. Our findings revealed that surface instability had an impact on DJ performance, thigh/shank muscle activity, and knee joint kinematics. In addition, the single factors "footwear" and "sex" modulated knee joint kinematics during DJs. However, hardly any significant interaction effects were found. Thus, additional footwear-related effects can be neglected when performing DJs during training on different surfaces.}, language = {en} } @article{LesinskiPrieskeBeurskensetal.2017, author = {Lesinski, Melanie and Prieske, Olaf and Beurskens, Rainer and Behm, David George and Granacher, Urs}, title = {Effects of drop height and surface instability on neuromuscular activation during drop jumps}, series = {Scandinavian journal of medicine \& science in sports}, volume = {27}, journal = {Scandinavian journal of medicine \& science in sports}, publisher = {Wiley}, address = {Hoboken}, issn = {0905-7188}, doi = {10.1111/sms.12732}, pages = {1090 -- 1098}, year = {2017}, abstract = {The purpose of this study was to examine whether drop height-induced changes in leg muscle activity during drop jumps (DJ) are additionally modulated by surface condition. Twenty-four healthy participants (23.7 +/- 1.8years) performed DJs on a force plate on stable, unstable, and highly unstable surfaces using different drop heights (i.e., 20cm, 40cm, 60cm). Electromyographic (EMG) activity of soleus (SOL), gastrocnemius (GM), tibialis anterior (TA) muscles and coactivation of TA/SOL and TA/GM were analyzed for time intervals 100ms prior to ground contact (preactivation) and 30-60ms after ground contact [short latency response (SLR)]. Increasing drop heights resulted in progressively increased SOL and GM activity during preactivation and SLR (P<0.01; 1.01 d 5.34) while TA/SOL coactivation decreased (P<0.05; 0.51 d 3.01). Increasing surface instability produced decreased activities during preactivation (GM) and SLR (GM, SOL) (P<0.05; 1.36 d 4.30). Coactivation increased during SLR (P<0.05; 1.50 d 2.58). A significant drop heightxsurface interaction was observed for SOL during SLR. Lower SOL activity was found on unstable compared to stable surfaces for drop heights 40cm (P<0.05; 1.25 d 2.12). Findings revealed that instability-related changes in activity of selected leg muscles are minimally affected by drop height.}, language = {en} } @article{LesinskiPrieskeDempsetal.2016, author = {Lesinski, Melanie and Prieske, Olaf and Demps, Marie and Granacher, Urs}, title = {Effects of fatigue and surface instability on neuromuscular performance during jumping}, series = {Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der {\~A}-sterreichischen Schmerzgesellschaft und der Deutschen Interdisziplin{\~A}\iren Vereinigung f{\~A}¼r Schmerztherapie}, volume = {26}, journal = {Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der {\~A}-sterreichischen Schmerzgesellschaft und der Deutschen Interdisziplin{\~A}\iren Vereinigung f{\~A}¼r Schmerztherapie}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0905-7188}, doi = {10.1111/sms.12548}, pages = {1140 -- 1150}, year = {2016}, abstract = {It has previously been shown that fatigue and unstable surfaces affect jump performance. However, the combination thereof is unresolved. Thus, the purpose of this study was to examine the effects of fatigue and surface instability on jump performance and leg muscle activity. Twenty elite volleyball players (18 +/- 2 years) performed repetitive vertical double-leg box jumps until failure. Before and after a fatigue protocol, jump performance (i.e., jump height) and electromyographic activity of selected lower limb muscles were recorded during drop jumps (DJs) and countermovement jumps (CMJs) on a force plate on stable and unstable surfaces (i.e., balance pad on top of force plate). Jump performance (3-7\%; P < 0.05; 1.14 <= d <= 2.82), and muscle activity (2-27\%; P < 0.05; 0.59 <= d <= 3.13) were lower following fatigue during DJs and CMJs, and on unstable compared with stable surfaces during DJs only (jump performance: 8\%; P < 0.01; d = 1.90; muscle activity: 9-25\%; P < 0.05; 1.08 <= d <= 2.54). No statistically significant interactions of fatigue by surface condition were observed. Our findings revealed that fatigue impairs neuromuscular performance during DJs and CMJs in elite volleyball players, whereas surface instability affects neuromuscular DJ performance only. Absent fatigue x surface interactions indicate that fatigue-induced changes in jump performance are similar on stable and unstable surfaces in jump-trained athletes.}, language = {en} } @phdthesis{Engel2016, author = {Engel, Tilman}, title = {Motor control strategies in response to unexpected disturbances of dynamic postural control in people with and without low back pain}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-400742}, school = {Universit{\"a}t Potsdam}, pages = {110}, year = {2016}, abstract = {Background: Low back pain (LBP) is one of the world wide leading causes of limited activity and disability. Impaired motor control has been found to be one of the possible factors related to the development or persistence of LBP. In particularly, motor control strategies seemed to be altered in situations requiring reactive responses of the trunk counteracting sudden external forces. However, muscular responses were mostly assessed in (quasi) static testing situations under simplified laboratory conditions. Comprehensive investigations in motor control strategies during dynamic everyday situations are lacking. The present research project aimed to investigate muscular compensation strategies following unexpected gait perturbations in people with and without LBP. A novel treadmill stumbling protocol was tested for its validity and reliability to provoke muscular reflex responses at the trunk and the lower extremities (study 1). Thereafter, motor control strategies in response to sudden perturbations were compared between people with LBP and asymptomatic controls (CTRL) (study 2). In accordance with more recent concepts of motor adaptation to pain, it was hypothesized that pain may have profound consequences on motor control strategies in LBP. Therefore, it was investigated whether differences in compensation strategies were either consisting of changes local to the painful area at the trunk, or also being present in remote areas such as at the lower extremities. Methods: All investigations were performed on a custom build split-belt treadmill simulating trip-like events by unexpected rapid deceleration impulses (amplitude: 2 m/s; duration: 100 ms; 200 ms after heel contact) at 1m/s baseline velocity. A total number of 5 (study 1) and 15 (study 2) right sided perturbations were applied during walking trials. Muscular activities were assessed by surface electromyography (EMG), recorded at 12 trunk muscles and 10 (study 1) respectively 5 (study 2) leg muscles. EMG latencies of muscle onset [ms] were retrieved by a semi-automatic detection method. EMG amplitudes (root mean square (RMS)) were assessed within 200 ms post perturbation, normalized to full strides prior to any perturbation [RMS\%]. Latency and amplitude investigations were performed for each muscle individually, as well as for pooled data of muscles grouped by location. Characteristic pain intensity scores (CPIS; 0-100 points, von Korff) based on mean intensity ratings reported for current, worst and average pain over the last three months were used to allocate participants into LBP (≥30 points) or CTRL (≤10 points). Test-retest reproducibility between measurements was determined by a compilation of measures of reliability. Differences in muscular activities between LBP and CTRL were analysed descriptively for individual muscles; differences based on grouped muscles were statistically tested by using a multivariate analysis of variance (MANOVA, α =0.05). Results: Thirteen individuals were included into the analysis of study 1. EMG latencies revealed reflex muscle activities following the perturbation (mean: 89 ms). Respective EMG amplitudes were on average 5-fold of those assessed in unperturbed strides, though being characterized by a high inter-subject variability. Test-retest reliability of muscle latencies showed a high reproducibility, both for muscles at the trunk and legs. In contrast, reproducibility of amplitudes was only weak to moderate for individual muscles, but increased when being assessed as a location specific outcome summary of grouped muscles. Seventy-six individuals were eligible for data analysis in study 2. Group allocation according to CPIS resulted in n=25 for LBP and n=29 for CTRL. Descriptive analysis of activity onsets revealed longer delays for all muscles within LBP compared to CTRL (trunk muscles: mean 10 ms; leg muscles: mean 3 ms). Onset latencies of grouped muscles revealed statistically significant differences between LBP and CTRL for right (p=0.009) and left (p=0.007) abdominal muscle groups. EMG amplitude analysis showed a high variability in activation levels between individuals, independent of group assignment or location. Statistical testing of grouped muscles indicated no significant difference in amplitudes between LBP and CTRL. Discussion: The present research project could show that perturbed treadmill walking is suitable to provoke comprehensive reflex responses at the trunk and lower extremities, both in terms of sudden onsets and amplitudes of reflex activity. Moreover, it could demonstrate that sudden loadings under dynamic conditions provoke an altered reflex timing of muscles surrounding the trunk in people with LBP compared to CTRL. In line with previous investigations, compensation strategies seemed to be deployed in a task specific manner, with differences between LBP and CTRL being evident predominately at ventral sides. No muscular alterations exceeding the trunk could be found when being assessed under the automated task of locomotion. While rehabilitation programs tailored towards LBP are still under debate, it is tempting to urge the implementation of dynamic sudden loading incidents of the trunk to enhance motor control and thereby to improve spinal protection. Moreover, in respect to the consistently observed task specificity of muscular compensation strategies, such a rehabilitation program should be rich in variety.}, language = {en} } @article{LaineMartinezValdesFallaetal.2015, author = {Laine, Christopher M. and Martinez-Valdes, Eduardo Andr{\´e}s and Falla, Deborah and Mayer, Frank and Farina, Dario}, title = {Motor Neuron Pools of Synergistic Thigh Muscles Share Most of Their Synaptic Input}, series = {The journal of neuroscience}, volume = {35}, journal = {The journal of neuroscience}, number = {35}, publisher = {Society for Neuroscience}, address = {Washington}, issn = {0270-6474}, doi = {10.1523/JNEUROSCI.0240-15.2015}, pages = {12207 -- 12216}, year = {2015}, abstract = {Neural control of synergist muscles is not well understood. Presumably, each muscle in a synergistic group receives some unique neural drive and some drive that is also shared in common with other muscles in the group. In this investigation, we sought to characterize the strength, frequency spectrum, and force dependence of the neural drive to the human vastus lateralis and vastus medialis muscles during the production of isometric knee extension forces at 10 and 30\% of maximum voluntary effort. High-density surface electromyography recordings were decomposed into motor unit action potentials to examine the neural drive to each muscle. Motor unit coherence analysis was used to characterize the total neural drive to each muscle and the drive shared between muscles. Using a novel approach based on partial coherence analysis, we were also able to study specifically the neural drive unique to each muscle (not shared). The results showed that the majority of neural drive to the vasti muscles was a cross-muscle drive characterized by a force-dependent strength and bandwidth. Muscle-specific neural drive was at low frequencies (<5 Hz) and relatively weak. Frequencies of neural drive associated with afferent feedback (6 - 12 Hz) and with descending cortical input (similar to 20 Hz) were almost entirely shared by the two muscles, whereas low-frequency (<5 Hz) drive comprised shared (primary) and muscle-specific (secondary) components. This study is the first to directly investigate the extent of shared versus independent control of synergist muscles at the motor neuron level.}, language = {en} } @article{BaurHirschmuellerMuelleretal.2011, author = {Baur, Heiner and Hirschm{\"u}ller, Anja and M{\"u}ller, Steffen and Mayer, Frank}, title = {Neuromuscular activity of the peroneal muscle after foot orthoses therapy in runners}, series = {Medicine and science in sports and exercise : official journal of the American College of Sports Medicine}, volume = {43}, journal = {Medicine and science in sports and exercise : official journal of the American College of Sports Medicine}, number = {8}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {0195-9131}, doi = {10.1249/MSS.0b013e31820c64ae}, pages = {1500 -- 1506}, year = {2011}, abstract = {BAUR, H., A. HIRSCHMULLER, S. MULLER, and F. MAYER. Neuromuscular Activity of the Peroneal Muscle after Foot Orthoses Therapy in Runners. Med. Sci. Sports Exerc., Vol. 43, No. 8, pp. 1500-1506, 2011. Purpose: Foot orthoses are a standard option to treat overuse injury. Biomechanical data providing mechanisms of foot orthoses' effectiveness are sparse. Stability of the ankle joint complex might be a key factor. The purpose was therefore to analyze neuromuscular activity of the musculus peroneus longus in runners with overuse injury symptoms treated with foot orthoses. Methods: A total of 99 male and female runners with overuse injury symptoms randomized in a control group (CO) and an orthoses group (OR) were analyzed on a treadmill at 3.3 m.s(-1) before and after an 8-wk foot orthoses intervention. Muscular activity of the musculus peroneus longus was measured and quantified in the time domain (initial onset of activation (T-ini), time of maximal activity (T-max), total time of activation (T-tot)) and amplitude domain (amplitude in preactivation (A(pre)), weight acceptance (A(wa)), push-off (A(po))). Results: Peroneal activity in the time domain did not differ initially between CO and OR, and no effect was observed after therapy (T-ini: CO = -0.88 +/- 0.09, OR = -0.88 +/- 0.08 / T-max: CO = 0.14 +/- 0.06, OR = 0.15 +/- 0.06 / T-tot: CO = 0.40 +/- 0.09, OR = 0.41 +/- 0.09; P > 0.05). In preactivation (Apre), muscle activity was higher in OR after intervention (CO = 0.97 +/- 0.32, 95\% confidence interval = 0.90-1.05; OR = 1.18 +/- 0.43, 95\% confidence interval = 1.08-1.28; P = 0.003). There was no group or intervention effect during stance (A(wa): CO = 2.33 +/- 0.66, OR = 2.33 +/- 0.74 / A(po): CO = 0.80 +/- 0.41, OR = 0.88 +/- 0.40; P > 0.05). Conclusions: Enhanced muscle activation of the musculus peroneus longus in preactivation suggests an altered preprogrammed activity, which might lead to better ankle stability providing a possible mode of action for foot orthoses therapy.}, language = {en} }