@article{HuberLeziusReibisetal.2015,
  author    = {Huber, Matthias and Lezius, Susanne and Reibis, Rona Katharina and Treszl, Andras and Kujawinska, Dorota and Jakob, Stefanie and Wegscheider, Karl and V{\"o}ller, Heinz and Kreutz, Reinhold},
  title     = {A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy},
  series = {International journal of molecular sciences},
  volume    = {16},
  journal   = {International journal of molecular sciences},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms160817456},
  pages     = {17456 -- 17468},
  year      = {2015},
  abstract  = {Cytochrome P450 17A1 (CYP17A1) catalyses the formation and metabolism of steroid hormones. They are involved in blood pressure (BP) regulation and in the pathogenesis of left ventricular hypertrophy. Therefore, altered function of CYP17A1 due to genetic variants may influence BP and left ventricular mass. Notably, genome wide association studies supported the role of this enzyme in BP control. Against this background, we investigated associations between single nucleotide polymorphisms (SNPs) in or nearby the CYP17A1 gene with BP and left ventricular mass in patients with arterial hypertension and associated cardiovascular organ damage treated according to guidelines. Patients (n = 1007, mean age 58.0 +/- 9.8 years, 83\% men) with arterial hypertension and cardiac left ventricular ejection fraction (LVEF) 40\% were enrolled in the study. Cardiac parameters of left ventricular mass, geometry and function were determined by echocardiography. The cohort comprised patients with coronary heart disease (n = 823; 81.7\%) and myocardial infarction (n = 545; 54.1\%) with a mean LVEF of 59.9\% +/- 9.3\%. The mean left ventricular mass index (LVMI) was 52.1 +/- 21.2 g/m(2.7) and 485 (48.2\%) patients had left ventricular hypertrophy. There was no significant association of any investigated SNP (rs619824, rs743572, rs1004467, rs11191548, rs17115100) with mean 24 h systolic or diastolic BP. However, carriers of the rs11191548 C allele demonstrated a 7\% increase in LVMI (95\% CI: 1\%-12\%, p = 0.017) compared to non-carriers. The CYP17A1 polymorphism rs11191548 demonstrated a significant association with LVMI in patients with arterial hypertension and preserved LVEF. Thus, CYP17A1 may contribute to cardiac hypertrophy in this clinical condition.},
  language  = {en}
}
@misc{HuberLeziusReibisetal.,
  author    = {Huber, Matthias and Lezius, Susanne and Reibis, Rona Katharina and Treszl, Andras and Kujawinska, Dorota and Jakob, Stefanie and Wegscheider, Karl and V{\"o}ller, Heinz and Kreutz, Reinhold},
  title     = {A single nucleotide polymorphism near the CYP17A1 gene is associated with left ventricular mass in hypertensive patients under pharmacotherapy},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-400074},
  pages     = {13},
  abstract  = {Cytochrome P450 17A1 (CYP17A1) catalyses the formation and metabolism of steroid hormones. They are involved in blood pressure (BP) regulation and in the pathogenesis of left ventricular hypertrophy. Therefore, altered function of CYP17A1 due to genetic variants may influence BP and left ventricular mass. Notably, genome wide association studies supported the role of this enzyme in BP control. Against this background, we investigated associations between single nucleotide polymorphisms (SNPs) in or nearby the CYP17A1 gene with BP and left ventricular mass in patients with arterial hypertension and associated cardiovascular organ damage treated according to guidelines. Patients (n = 1007, mean age 58.0 ± 9.8 years, 83\% men) with arterial hypertension and cardiac left ventricular ejection fraction (LVEF) ≥40\% were enrolled in the study. Cardiac parameters of left ventricular mass, geometry and function were determined by echocardiography. The cohort comprised patients with coronary heart disease (n = 823; 81.7\%) and myocardial infarction (n = 545; 54.1\%) with a mean LVEF of 59.9\% ± 9.3\%. The mean left ventricular mass index (LVMI) was 52.1 ± 21.2 g/m2.7 and 485 (48.2\%) patients had left ventricular hypertrophy. There was no significant association of any investigated SNP (rs619824, rs743572, rs1004467, rs11191548, rs17115100) with mean 24 h systolic or diastolic BP. However, carriers of the rs11191548 C allele demonstrated a 7\% increase in LVMI (95\% CI: 1\%-12\%, p = 0.017) compared to non-carriers. The CYP17A1 polymorphism rs11191548 demonstrated a significant association with LVMI in patients with arterial hypertension and preserved LVEF. Thus, CYP17A1 may contribute to cardiac hypertrophy in this clinical condition.},
  language  = {en}
}
@inproceedings{VoellerSalzwedelReibisetal.2014,
  author    = {V{\"o}ller, Heinz and Salzwedel, Annett and Reibis, Rona Katharina and Kaminski, S. and Buhlert, Hermann and Eichler, Sarah and Wegscheider, Karl},
  title     = {Age and fitness level are strongest limitations of exercise capacity during inpatient cardiac rehabilitation},
  series = {European heart journal},
  volume    = {35},
  booktitle = {European heart journal},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {0195-668X},
  pages     = {899 -- 899},
  year      = {2014},
  language  = {en}
}
@article{HadzicEichlerVoelleretal.2022,
  author    = {Hadzic, Miralem and Eichler, Sarah and V{\"o}ller, Heinz and Salzwedel, Annett},
  title     = {Akzeptanz und Nutzung eines telemedizinischen Rehabilitationsprogramms f{\"u}r Patienten mit Knie- oder H{\"u}ft-Totalendoprothese},
  series = {Bewegungstherapie und Gesundheitssport : B \& G ; offizielles Organ des Deutschen Verbandes f{\"u}r Gesundheitssport und Sporttherapie e.V. (DVGS)},
  volume    = {38},
  journal   = {Bewegungstherapie und Gesundheitssport : B \& G ; offizielles Organ des Deutschen Verbandes f{\"u}r Gesundheitssport und Sporttherapie e.V. (DVGS)},
  number    = {01},
  publisher = {Thieme},
  address   = {Stuttgart},
  organization    = {Arbeitsgrp ReMove-It},
  issn      = {1613-0863},
  doi       = {10.1055/a-1714-3629},
  pages     = {20 -- 25},
  year      = {2022},
  abstract  = {Objective of the study: The long-term use of telemedical programs depends not only on their effectiveness, but also on patient acceptance and satisfaction. The effectiveness of telemedical exercise therapy for patients after implantation of a total knee or hip prosthesis and subsequent rehabilitation has already been examined in a randomized controlled study. This article focuses on the patient's acceptance and usage behaviour with regard to the tele-rehabilitation system. Methodology: 48 patients (53 +/- 7 years; 26 women; 35 hip/13 knee TEP) were questioned after a three-month telemedical movement therapy using the Telehealth Usability Questionnaire (TUQ) to determine the acceptance of the technology. The questionnaire consisted of 21 items (seven-point Likert scale) in six scales (e. g. usefulness, quality of interactions, reliability). System-specific questions were summarized on an additional scale. The results were presented as a percentage of the scale (100 estimates complete agreement). The usage behaviour was examined using system-generated process data for training and integrated voice/text messages. Results: The TUQ scales "Usefulness" (Mdn 95.2) and "Ease of use and learnability" (Mdn 92.9) were rated the highest, while "Reliability" (Mdn 57.1) and "Quality of interactions" ( Mdn 71.4) showed the lowest levels. The system-specific scale was placed in the upper quartile (Mdn 85.7). In the first week, 39 patients (81\%) and in the second 45 patients (94\%) performed at least one training exercise with the system. The proportion of active patients (>= 1 exercise/week) decreased in the further course to 75\% (n=36) in the 7th week and 48\% (n=23) in the 12th week. The system communication options were initially used frequently after the start of therapy: in the first week, 42 patients (88\%) sent messages, 47 patients (98\%) received messages from their therapist respectively. In week 7, 9 (19\%) and 13 (27\%) patients sent/received messages via the system respectively. Conclusion: Most of the patients perceived telemedical movement therapy as useful and user-friendly and seemed to be largely satisfied with the system. This proved to be well suited for short-term use of 6 to 8 weeks following subsequent rehabilitation.},
  language  = {de}
}
@article{SchulzBehrendtSalzwedelRabeetal.2017,
  author    = {Schulz-Behrendt, Claudia and Salzwedel, Annett and Rabe, Sophie and Ortmann, K. and V{\"o}ller, Heinz},
  title     = {Aspekte beruflicher und sozialer Wiedereingliederung aus Sicht kardiovaskul{\"a}r erkrankter Rehabilitanden in besonderen beruflichen Problemlagen},
  series = {Die Rehabilitation : Zeitschrift f{\"u}r Praxis und Forschung in der Rehabilitation},
  volume    = {56},
  journal   = {Die Rehabilitation : Zeitschrift f{\"u}r Praxis und Forschung in der Rehabilitation},
  number    = {3},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0034-3536},
  doi       = {10.1055/s-0042-121379},
  pages     = {181 -- 188},
  year      = {2017},
  abstract  = {Ziel: Untersucht wurden subjektive bio-psycho-soziale Auswirkungen chronischer Herz- und Gef{\"a}ßerkrankungen, Bew{\"a}ltigungsstrategien und Formen sozialer Unterst{\"u}tzung bei Rehabilitanden in besonderen beruflichen Problemlagen (BBPL). Methodik: F{\"u}r die qualitative Untersuchung wurden 17 Patienten (48,9±7,0 Jahre, 13 m{\"a}nnl.) mit BBPL (SIMBO-C>30) in leitfadengest{\"u}tzten Interviews befragt. Die Auswertung erfolgte softwaregest{\"u}tzt nach dem inhaltsanalytischen Ansatz von Mayring. Ergebnisse: Im Rahmen der Krankheitsauswirkungen benannten die Patienten soziale, einschließlich beruflicher Aspekte mit 62\% der Aussagen deutlich h{\"a}ufiger als physische oder psychische Faktoren (9 bzw. 29\%). Angewandte Bew{\"a}ltigungsstrategien und erfahrene Unterst{\"u}tzungsleistungen richteten sich jedoch {\"u}berwiegend auf k{\"o}rperliche Einschr{\"a}nkungen (70 bzw. 45\%). Schlussfolgerung: Obgleich soziale Krankheitsauswirkungen f{\"u}r die befragten Rehabilitanden subjektiv bedeutsam waren, gelang die Entwicklung geeigneter Bew{\"a}ltigungsstrategien nur unzureichen},
  language  = {de}
}
@misc{SchlittKamkeGuhaetal.2015,
  author    = {Schlitt, Axel and Kamke, Wolfram and Guha, Manju and Haberecht, Olaf and V{\"o}ller, Heinz},
  title     = {Atrial Fibrillation: The correct Procedure in the cardiac Rehabilitation},
  series = {Deutsche medizinische Wochenschrift : DMW ; Organ der Deutschen Gesellschaft f{\"u}r Innere Medizin (DGIM) ; Organ der Gesellschaft Deutscher Naturforscher und {\"A}rzte (GDN{\"A})},
  volume    = {140},
  journal   = {Deutsche medizinische Wochenschrift : DMW ; Organ der Deutschen Gesellschaft f{\"u}r Innere Medizin (DGIM) ; Organ der Gesellschaft Deutscher Naturforscher und {\"A}rzte (GDN{\"A})},
  number    = {13},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0012-0472},
  doi       = {10.1055/s-0041-102733},
  pages     = {1006 -- U100},
  year      = {2015},
  language  = {de}
}
@article{ReibisSalzwedelFalketal.2017,
  author    = {Reibis, Rona Katharina and Salzwedel, Annett and Falk, Johannes and V{\"o}ller, Heinz},
  title     = {Berufliche Wiedereingliederung nach akutem Herzinfarkt},
  series = {Deutsche medizinische Wochenschrift : DMW ; Organ der Deutschen Gesellschaft f{\"u}r Innere Medizin (DGIM) ; Organ der Gesellschaft Deutscher Naturforscher und {\"A}rzte (GDN{\"A})},
  volume    = {142},
  journal   = {Deutsche medizinische Wochenschrift : DMW ; Organ der Deutschen Gesellschaft f{\"u}r Innere Medizin (DGIM) ; Organ der Gesellschaft Deutscher Naturforscher und {\"A}rzte (GDN{\"A})},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0012-0472},
  doi       = {10.1055/s-0042-124425},
  pages     = {617 -- 624},
  year      = {2017},
  abstract  = {Die berufliche Wiedereingliederung von Patienten nach akutem Herzinfarkt stellt sowohl aus gesellschaftlicher wie auch aus individueller Sicht einen entscheidenden Schritt zur vollst{\"a}ndigen Rekonvaleszenz dar. Lediglich 10\% der Patienten werden durch kardiale Probleme an der Reintegration behindert. Neben medizinischen und berufsbezogenen Faktoren determinieren insbesondere psychosoziale Parameter eine erfolgreiche Wiederaufnahme der T{\"a}tigkeit. Verschiedene Programme der Rentenversicherungstr{\"a}ger werden dabei unterst{\"u}tzend angeboten.},
  language  = {de}
}
@article{SchwaabRauchVoelleretal.2020,
  author    = {Schwaab, Bernhard and Rauch, Bernhard and V{\"o}ller, Heinz and Benzer, Werner and Schmid, Jean-Paul},
  title     = {Beyond randomised studies},
  series = {European journal of preventive cardiology : the official ESC journal for primary \& secondary cardiovascular prevention, rehabilitation and sports cardiology},
  volume    = {28},
  journal   = {European journal of preventive cardiology : the official ESC journal for primary \& secondary cardiovascular prevention, rehabilitation and sports cardiology},
  number    = {17},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {2047-4873},
  doi       = {10.1177/2047487320936782},
  pages     = {E17 -- E19},
  year      = {2020},
  language  = {en}
}
@article{SalzwedelVoeller2021,
  author    = {Salzwedel, Annett and V{\"o}ller, Heinz},
  title     = {Cardiac rehabilitation},
  series = {Deutsches {\"A}rzteblatt international : a weekly online journal of clinical medicine and public health},
  volume    = {118},
  journal   = {Deutsches {\"A}rzteblatt international : a weekly online journal of clinical medicine and public health},
  number    = {29-30},
  publisher = {Dt. {\"A}rzte-Verl.},
  address   = {Cologne},
  organization    = {OutCaRe Investigators},
  issn      = {1866-0452},
  doi       = {10.3238/arztebl.m2021.0211},
  pages     = {505 -- 506},
  year      = {2021},
  language  = {en}
}
@inproceedings{VoellerSalzwedelReibisetal.2015,
  author    = {V{\"o}ller, Heinz and Salzwedel, Annett and Reibis, Rona Katharina and Eichler, Sarah and Buhlert, Hermann and Kaminski, Stefan and Wegscheider, Karl},
  title     = {Cardiopulmonary exercise testing is predictive of return to work in cardiac patients after multicomponent rehabilitation},
  series = {European heart journal},
  volume    = {36},
  booktitle = {European heart journal},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {0195-668X},
  pages     = {635 -- 636},
  year      = {2015},
  language  = {en}
}