@article{BoedekerBetaFranketal.2010, author = {Boedeker, Hendrik Ulrich and Beta, Carsten and Frank, Till D. and Bodenschatz, Eberhard}, title = {Quantitative analysis of random ameboid motion}, issn = {0295-5075}, doi = {10.1209/0295-5075/90/28005}, year = {2010}, abstract = {We quantify random migration of the social ameba Dictyostelium discoideum. We demonstrate that the statistics of cell motion can be described by an underlying Langevin-type stochastic differential equation. An analytic expression for the velocity distribution function is derived. The separation into deterministic and stochastic parts of the movement shows that the cells undergo a damped motion with multiplicative noise. Both contributions to the dynamics display a distinct response to external physiological stimuli. The deterministic component depends on the developmental state and ambient levels of signaling substances, while the stochastic part does not.}, language = {en} }