@incollection{CarlaUhink2024, author = {Carl{\`a}-Uhink, Filippo}, title = {'Per voler del primo amor ch'i' sento'}, series = {Representing Rome's emperors: historical and cultural perspectives through time}, booktitle = {Representing Rome's emperors: historical and cultural perspectives through time}, publisher = {Oxford University Press}, address = {Oxford}, isbn = {978-0-19-286926-5}, pages = {195 -- 213}, year = {2024}, language = {en} } @book{GurskyThoene2024, author = {Gursky, Karl-Heinz and Th{\"o}ne, Meike}, title = {20 Probleme aus dem Eigent{\"u}mer-Besitzer-Verh{\"a}ltnis}, series = {Klausurprobleme : Juristische {\"U}bungsb{\"u}cher}, journal = {Klausurprobleme : Juristische {\"U}bungsb{\"u}cher}, edition = {10., {\"u}berarbeitete}, publisher = {Vahlen}, address = {M{\"u}nchen}, isbn = {978-3-8006-7161-8}, pages = {XV, 125}, year = {2024}, abstract = {Zum Werk Der Band zum Eigent{\"u}mer-Besitzer-Verh{\"a}ltnis erscheint nunmehr in 10. Auflage und behandelt in bew{\"a}hrter Darstellungsform die wichtigsten in den {\"U}bungen und im Examen zur Bearbeitung gestellten Streitfragen aus diesem Bereich des Sachenrechts. Die einzelnen Probleme werden anhand von Beispielf{\"a}llen erkl{\"a}rt, die in Lehre und Rechtsprechung vertretenen Meinungen werden einander dabei gegen{\"u}bergestellt, die sie tragenden Argumente werden in K{\"u}rze herausgearbeitet und an weiteren F{\"a}llen erprobt. Auf diese Weise entwickeln Studierende das f{\"u}r die Falll{\"o}sung relevante juristische Problembewusstsein sowie die F{\"a}higkeit, die verschiedenen Ansichten und Argumente gegeneinander abzuw{\"a}gen, eine eigene Meinung zu bilden und sie {\"u}berzeugend zu begr{\"u}nden. Vorteile auf einen Blick alle relevanten Probleme zum Eigent{\"u}mer-Besitzer-Verh{\"a}ltnis in einem Band umfassende Fundstellensammlung f{\"u}r die in Lehre und Rechtsprechung vertretenen Meinungen Zur Neuauflage F{\"u}r die Neuauflage wurden die aktuelle Literatur sowie die neueste Rechtsprechung eingearbeitet sowie ein Abschnitt zum Aufbau von Meinungsstreits in Pr{\"u}fungen erg{\"a}nzt. Zielgruppe F{\"u}r Studierende der Rechtswissenschaften, Rechtsreferendarinnen und -referendare und AG-Leiterinnen und -Leiter.}, language = {de} } @article{Kosman2024, author = {Kosman, Admiʾel}, title = {?של מי הנקמה}, series = {אלכסון}, journal = {אלכסון}, year = {2024}, language = {mul} } @phdthesis{Stange2024, author = {Stange, Maike}, title = {A study on Coronin-A and Aip1 function in motility of Dictyostelium discoideum and on Aip1 interchangeability between Dictyostelium discoideum and Arabidopsis thaliana}, doi = {10.25932/publishup-62856}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-628569}, school = {Universit{\"a}t Potsdam}, pages = {xiv, 168}, year = {2024}, abstract = {Actin is one of the most highly conserved proteins in eukaryotes and distinct actin-related proteins with filament-forming properties are even found in prokaryotes. Due to these commonalities, actin-modulating proteins of many species share similar structural properties and proposed functions. The polymerization and depolymerization of actin are critical processes for a cell as they can contribute to shape changes to adapt to its environment and to move and distribute nutrients and cellular components within the cell. However, to what extent functions of actin-binding proteins are conserved between distantly related species, has only been addressed in a few cases. In this work, functions of Coronin-A (CorA) and Actin-interacting protein 1 (Aip1), two proteins involved in actin dynamics, were characterized. In addition, the interchangeability and function of Aip1 were investigated in two phylogenetically distant model organisms. The flowering plant Arabidopsis thaliana (encoding two homologs, AIP1-1 and AIP1-2) and in the amoeba Dictyostelium discoideum (encoding one homolog, DdAip1) were chosen because the functions of their actin cytoskeletons may differ in many aspects. Functional analyses between species were conducted for AIP1 homologs as flowering plants do not harbor a CorA gene. In the first part of the study, the effect of four different mutation methods on the function of Coronin-A protein and the resulting phenotype in D. discoideum was revealed in two genetic knockouts, one RNAi knockdown and a sudden loss-of-function mutant created by chemical-induced dislocation (CID). The advantages and disadvantages of the different mutation methods on the motility, appearance and development of the amoebae were investigated, and the results showed that not all observed properties were affected with the same intensity. Remarkably, a new combination of Selection-Linked Integration and CID could be established. In the second and third parts of the thesis, the exchange of Aip1 between plant and amoeba was carried out. For A. thaliana, the two homologs (AIP1-1 and AIP1-2) were analyzed for functionality as well as in D. discoideum. In the Aip1-deficient amoeba, rescue with AIP1-1 was more effective than with AIP1-2. The main results in the plant showed that in the aip1-2 mutant background, reintroduced AIP1-2 displayed the most efficient rescue and A. thaliana AIP1-1 rescued better than DdAip1. The choice of the tagging site was important for the function of Aip1 as steric hindrance is a problem. The DdAip1 was less effective when tagged at the C-terminus, while the plant AIP1s showed mixed results depending on the tag position. In conclusion, the foreign proteins partially rescued phenotypes of mutant plants and mutant amoebae, despite the organisms only being very distantly related in evolutionary terms.}, language = {en} } @techreport{EstrinKhavulKritikosetal.2024, type = {Working Paper}, author = {Estrin, Saul and Khavul, Susanna and Kritikos, Alexander and L{\"o}her, Jonas}, title = {Access to digital finance}, series = {CEPA Discussion Papers}, journal = {CEPA Discussion Papers}, number = {72}, issn = {2628-653X}, doi = {10.25932/publishup-62326}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-623261}, pages = {27}, year = {2024}, abstract = {Financing entrepreneurship spurs innovation and economic growth. Digital financial platforms that crowdfund equity for entrepreneurs have emerged globally, yet they remain poorly understood. We model equity crowdfunding in terms of the relationship between the number of investors and the amount of money raised per pitch. We examine heterogeneity in the average amount raised per pitch that is associated with differences across three countries and seven platforms. Using a novel dataset of successful fundraising on the most prominent platforms in the UK, Germany, and the USA, we find the underlying relationship between the number of investors and the amount of money raised for entrepreneurs is loglinear, with a coefficient less than one and concave to the origin. We identify significant variation in the average amount invested in each pitch across countries and platforms. Our findings have implications for market actors as well as regulators who set competitive frameworks.}, language = {en} } @phdthesis{Schmidt2024, author = {Schmidt, Lena Katharina}, title = {Altered hydrological and sediment dynamics in high-alpine areas - Exploring the potential of machine-learning for estimating past and future changes}, doi = {10.25932/publishup-62330}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-623302}, school = {Universit{\"a}t Potsdam}, pages = {xxi, 129}, year = {2024}, abstract = {Climate change fundamentally transforms glaciated high-alpine regions, with well-known cryospheric and hydrological implications, such as accelerating glacier retreat, transiently increased runoff, longer snow-free periods and more frequent and intense summer rainstorms. These changes affect the availability and transport of sediments in high alpine areas by altering the interaction and intensity of different erosion processes and catchment properties. Gaining insight into the future alterations in suspended sediment transport by high alpine streams is crucial, given its wide-ranging implications, e.g. for flood damage potential, flood hazard in downstream river reaches, hydropower production, riverine ecology and water quality. However, the current understanding of how climate change will impact suspended sediment dynamics in these high alpine regions is limited. For one, this is due to the scarcity of measurement time series that are long enough to e.g. infer trends. On the other hand, it is difficult - if not impossible - to develop process-based models, due to the complexity and multitude of processes involved in high alpine sediment dynamics. Therefore, knowledge has so far been confined to conceptual models (which do not facilitate deriving concrete timings or magnitudes for individual catchments) or qualitative estimates ('higher export in warmer years') that may not be able to capture decreases in sediment export. Recently, machine-learning approaches have gained in popularity for modeling sediment dynamics, since their black box nature tailors them to the problem at hand, i.e. relatively well-understood input and output data, linked by very complex processes. Therefore, the overarching aim of this thesis is to estimate sediment export from the high alpine {\"O}tztal valley in Tyrol, Austria, over decadal timescales in the past and future - i.e. timescales relevant to anthropogenic climate change. This is achieved by informing, extending, evaluating and applying a quantile regression forest (QRF) approach, i.e. a nonparametric, multivariate machine-learning technique based on random forest. The first study included in this thesis aimed to understand present sediment dynamics, i.e. in the period with available measurements (up to 15 years). To inform the modeling setup for the two subsequent studies, this study identified the most important predictors, areas within the catchments and time periods. To that end, water and sediment yields from three nested gauges in the upper {\"O}tztal, Vent, S{\"o}lden and Tumpen (98 to almost 800 km² catchment area, 930 to 3772 m a.s.l.) were analyzed for their distribution in space, their seasonality and spatial differences therein, and the relative importance of short-term events. The findings suggest that the areas situated above 2500 m a.s.l., containing glacier tongues and recently deglaciated areas, play a pivotal role in sediment generation across all sub-catchments. In contrast, precipitation events were relatively unimportant (on average, 21 \% of annual sediment yield was associated to precipitation events). Thus, the second and third study focused on the Vent catchment and its sub-catchment above gauge Vernagt (11.4 and 98 km², 1891 to 3772 m a.s.l.), due to their higher share of areas above 2500 m. Additionally, they included discharge, precipitation and air temperature (as well as their antecedent conditions) as predictors. The second study aimed to estimate sediment export since the 1960s/70s at gauges Vent and Vernagt. This was facilitated by the availability of long records of the predictors, discharge, precipitation and air temperature, and shorter records (four and 15 years) of turbidity-derived sediment concentrations at the two gauges. The third study aimed to estimate future sediment export until 2100, by applying the QRF models developed in the second study to pre-existing precipitation and temperature projections (EURO-CORDEX) and discharge projections (physically-based hydroclimatological and snow model AMUNDSEN) for the three representative concentration pathways RCP2.6, RCP4.5 and RCP8.5. The combined results of the second and third study show overall increasing sediment export in the past and decreasing export in the future. This suggests that peak sediment is underway or has already passed - unless precipitation changes unfold differently than represented in the projections or changes in the catchment erodibility prevail and override these trends. Despite the overall future decrease, very high sediment export is possible in response to precipitation events. This two-fold development has important implications for managing sediment, flood hazard and riverine ecology. This thesis shows that QRF can be a very useful tool to model sediment export in high-alpine areas. Several validations in the second study showed good performance of QRF and its superiority to traditional sediment rating curves - especially in periods that contained high sediment export events, which points to its ability to deal with threshold effects. A technical limitation of QRF is the inability to extrapolate beyond the range of values represented in the training data. We assessed the number and severity of such out-of-observation-range (OOOR) days in both studies, which showed that there were few OOOR days in the second study and that uncertainties associated with OOOR days were small before 2070 in the third study. As the pre-processed data and model code have been made publically available, future studies can easily test further approaches or apply QRF to further catchments.}, language = {en} } @phdthesis{Doerries2024, author = {D{\"o}rries, Timo Julian}, title = {Anomalous transport and non-Gaussian dynamics in mobile-immobile models}, doi = {10.25932/publishup-63495}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-634959}, school = {Universit{\"a}t Potsdam}, pages = {ii, 177}, year = {2024}, abstract = {The mobile-immobile model (MIM) has been established in geoscience in the context of contaminant transport in groundwater. Here the tracer particles effectively immobilise, e.g., due to diffusion into dead-end pores or sorption. The main idea of the MIM is to split the total particle density into a mobile and an immobile density. Individual tracers switch between the mobile and immobile state following a two-state telegraph process, i.e., the residence times in each state are distributed exponentially. In geoscience the focus lies on the breakthrough curve (BTC), which is the concentration at a fixed location over time. We apply the MIM to biological experiments with a special focus on anomalous scaling regimes of the mean squared displacement (MSD) and non-Gaussian displacement distributions. As an exemplary system, we have analysed the motion of tau proteins, that diffuse freely inside axons of neurons. Their free diffusion thereby corresponds to the mobile state of the MIM. Tau proteins stochastically bind to microtubules, which effectively immobilises the tau proteins until they unbind and continue diffusing. Long immobilisation durations compared to the mobile durations give rise to distinct non-Gaussian Laplace shaped distributions. It is accompanied by a plateau in the MSD for initially mobile tracer particles at relevant intermediate timescales. An equilibrium fraction of initially mobile tracers gives rise to non-Gaussian displacements at intermediate timescales, while the MSD remains linear at all times. In another setting bio molecules diffuse in a biosensor and transiently bind to specific receptors, where advection becomes relevant in the mobile state. The plateau in the MSD observed for the advection-free setting and long immobilisation durations persists also for the case with advection. We find a new clear regime of anomalous diffusion with non-Gaussian distributions and a cubic scaling of the MSD. This regime emerges for initially mobile and for initially immobile tracers. For an equilibrium fraction of initially mobile tracers we observe an intermittent ballistic scaling of the MSD. The long-time effective diffusion coefficient is enhanced by advection, which we physically explain with the variance of mobile durations. Finally, we generalize the MIM to incorporate arbitrary immobilisation time distributions and focus on a Mittag-Leffler immobilisation time distribution with power-law tail ~ t^(-1-mu) with 0