@inproceedings{LausbergKazzerHeekerenetal.2012, author = {Lausberg, H. and Kazzer, Philipp and Heekeren, Hauke and Wartenburger, Isabell}, title = {Differential cortical mechanisms underlying tool use, pantomime, and body-part-as-object use}, series = {European journal of neurology : the official journal of the European Federation of Neurological Societies}, volume = {19}, booktitle = {European journal of neurology : the official journal of the European Federation of Neurological Societies}, number = {9}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {1351-5101}, pages = {78 -- 78}, year = {2012}, language = {en} } @article{LausbergKazzerHeekerenetal.2015, author = {Lausberg, Hedda and Kazzer, Philipp and Heekeren, Hauke R. and Wartenburger, Isabell}, title = {Pantomiming tool use with an imaginary tool in hand as compared to demonstration with tool in hand specifically modulates the left middle and superior temporal gyri}, series = {Cortex : a journal devoted to the study of the nervous system and behaviour}, volume = {71}, journal = {Cortex : a journal devoted to the study of the nervous system and behaviour}, publisher = {Elsevier}, address = {Milano}, issn = {0010-9452}, pages = {1 -- 14}, year = {2015}, abstract = {Neuropsychological lesion studies evidence the necessity to differentiate between various forms of tool-related actions such as real tool use, tool use demonstration with tool in hand and without physical target object, and pantomime without tool in hand. However, thus far, neuroimaging studies have primarily focused only on investigating tool use pantomimes. The present fMRI study investigates pantomime without tool in hand as compared to tool use demonstration with tool in hand in order to explore patterns of cerebral signal modulation associated with acting with imaginary tools in hand. Fifteen participants performed with either hand (i) tool use pantomime with an imaginary tool in hand in response to visual tool presentation and (ii) tool use demonstration with tool in hand in response to visual-tactile tool presentation. In both conditions, no physical target object was present. The conjunction analysis of the right and left hands executions of tool use pantomime relative to tool use demonstration yielded significant activity in the left middle and superior temporal lobe. In contrast, demonstration relative to pantomime revealed large bihemispherically distributed homologous areas of activity. Thus far, fMRI studies have demonstrated the relevance of the left middle and superior temporal gyri in viewing, naming, and matching tools and related actions and contexts. Since in our study all these factors were equally (ir)relevant both in the tool use pantomime and the tool use demonstration conditions, the present findings enhance the knowledge about the function of these brain regions in tool-related cognitive processes. The two contrasted conditions only differ regarding the fact that the pantomime condition requires the individual to act with an imaginary tool in hand. Therefore, we suggest that the left middle and superior temporal gyri are specifically involved in integrating the projected mental image of a tool in the execution of a tool-specific movement concept. (C) 2015 Elsevier Ltd. All rights reserved.}, language = {en} } @article{MeriauKazzerWartenburgeretal.2005, author = {M{\´e}riau, Katja and Kazzer, Philipp and Wartenburger, Isabell and Prehn, Kristin and Lammers, Claas-Hinrich and Villringer, Arno and Heekeren, Hauke}, title = {Neural correlates of individual differences in the ability to identify and communicate one's emotional state}, issn = {0898-929X}, year = {2005}, language = {en} } @article{MeriauWartenburgerKazzeretal.2006, author = {M{\´e}riau, Katja and Wartenburger, Isabell and Kazzer, Philipp and Prehn, Kristin and Lammers, Claas-Hinrich and van der Meer, Elke and Villringer, Arno and Heekeren, Hauke R.}, title = {A neural network reflecting individual differences in cognitive processing of emotions during perceptual decision making}, issn = {1053-8119}, year = {2006}, language = {en} } @article{MeriauWartenburgerKazzeretal.2009, author = {M{\´e}riau, Katja and Wartenburger, Isabell and Kazzer, Philipp and Prehn, Kristin and Villringer, Arno and van der Meer, Elke and Heekeren, Hauke R.}, title = {Insular activity during passive viewing of aversive stimuli reflects individual differences in state negative affect}, issn = {0278-2626}, doi = {10.1016/j.bandc.2008.05.006}, year = {2009}, abstract = {People differ with regard to how they perceive, experience, and express negative affect. While trait negative affect reflects a stable, sustained personality trait, state negative affect represents a stimulus limited and temporally acute emotion. So far, little is known about the neural systems mediating the relationship between negative affect and acute emotion processing. To address this issue we investigated in a healthy female sample how individual differences in state negative affect are reflected in changes in blood oxygen level-dependent responses during passive viewing of emotional stimuli. To assess autonomic arousal we simultaneously recorded changes in skin conductance level. At the psychophysiological level we found increased skin conductance level in response to aversive relative to neutral pictures. However, there was no association of state negative affect with skin conductance level. At the neural level we found that high state negative affect was associated with increased left insular activity during passive viewing of aversive stimuli. The insula has been implicated in interoceptive processes and in the integration of sensory, visceral, and affective information thus contributing to subjective emotional experience. Greater recruitment of the insula in response to aversive relative to neutral stimuli in subjects with high state negative affect may represent increased processing of salient aversive stimuli.}, language = {en} }