@misc{Peter1980, author = {Peter, Martin G.}, title = {Products of in vitro oxidation of N-acetyldopamine as possible components in the sclerotization of insect cuticle}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16759}, year = {1980}, abstract = {[1-14C]-N-Acetyldopamine (NADA) was oxidized in the presence of methyl [3-3H]-β-alanate with mushroom tyrosinase. The complex mixture of reaction products was partly resolved by chromatographic procedures and analyzed by spectroscopic methods. Methyl-β-alanate is incorporated to only a small extent into oxidation products of NADA which inter alia are presumed to be oligomeric hydroxyquinones. After oxidation of [1-14C, 2-3H]-NADA with preparations from tanning Manduca sexta pupal cuticle, N-acetylnoradrenalin was identified as one of the products. Binding of radioactivity to melanin-like material was also observed. These results suggest that oxidation products different from those formulated usually for the crosslinkages between protein amino groups and N-acetyldopaquinone are deposited in darkly brown coloured insect cuticles during sclerotization.}, language = {en} } @misc{Kliegl1981, author = {Kliegl, Reinhold}, title = {Automated and interactive analysis of eye fixation data in reading}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-39861}, year = {1981}, abstract = {A package of five FORTRAN programs that provides for fast user-controlled analyses of reading eye fixations is described. The package requires the data to be in a fixation format and to be rescaled to screen dimensions. OLDEYE identifies six types of fixations and calculates descriptive statistics on each of them, on their associated saccades, and on their average pupil diameter. CONVRT represents the text as a string of words that can be coded according to experimentally relevant variables. PLTFIX prints fixation durations by letter position and sequence of occurrence. MODDAT is an interactive program for marking parts of the text in which the data quality is below acceptable standards. It also allows the correction of systematic errors due to calibration or drift. MATCH combines the outputs from OLDEYE, CONVRT, and MODDAT and calculates 11 dependent measures for every word. The output of MATCH is suitable for input to conventional multivariate statistical programs.}, language = {en} } @misc{KlieglOlson1981, author = {Kliegl, Reinhold and Olson, Richard K.}, title = {Reduction and calibration of eye monitor data}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-39875}, year = {1981}, abstract = {The present paper presents FORTRAN programs for reducing eye monitor output to fixations and for mapping these fixations to locations in the stimulus space. Flexible parameters of the fixations program allow for determination of the beginning and end of fixations under different resolution criteria and for indicating loss of accurate measurement. The calibration program is based on a rectangular 9-point fixation grid. Each fixation is rescaled within this grid by solving for a quadratic equation. The rescaled values are output in a flexibly determined rectangular coordinate system that is related to the stimulus space, such as character position on the screen. The programs were developed for the 60-Hz Applied Sciences corneal reflection eye monitor, but they may be used with a number of other systems.}, language = {en} } @misc{PueschelMentleinHeymann1982, author = {P{\"u}schel, Gerhard Paul and Mentlein, Rolf and Heymann, Eberhard}, title = {Isolation and characterization of Dipeptidyl Peptidase IV from human placenta}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-45875}, year = {1982}, abstract = {Human placenta is surprisingly rich in post-proline dipeptidyl peptidase activity. Among various cell fractions, microsomes have the highest specific activity. A homogeneous enzyme preparation is obtained in a six-step purification procedure. The final preparation appears homogeneous upon dodecyl sulfate electrophoresis, but analytical isoelectric focussing reveals various active bands with isoelectric points in the range of pH 3 - 4. The enzyme is a glycoprotein containing about 30\% carbohydrate. Treatment with neuraminidase lowers the isoelectric points but does not reduce the heterogeneity of the band pattern. The subunit molecular weight is 120000 as estimated by dodecyl sulfate electrophoresis, whereas Mr of the native enzyme is > 200000, as can be concluded from gel filtration experiments. The purified dipeptidyl peptidase cleaves various synthetic and natural peptides, including substance P, kentsin, casomorphin and a synthetic renin inhibitor. In general, the specificity of the placenta peptidase is similar to that of post-proline dipeptidyl peptidase from other sources. Phenylalanylprolyl-P-naphthylamide (Km = 0.02 mM, I/ = 92 Ujmg) is the best substrate among various synthetic peptide derivatives. Only peptides with a free N-terminal amino group and proline, hydroxyproline, or alanine in position 2 of the N-terminal sequence are cieaved. However, X-Pro-Pro- . . . structures, e. g. as in bradykinin, are not attacked. 1 mM bis-(6nitrophenyI)phosphate or 1 mM diisopropylfluorophosphate completely inactivate the peptidase within 30 min at 30°C (pH 8). The peptidase is also completely inhibited by 1 mM Zn²⁺ and by other heavy metals.}, language = {en} } @misc{KlieglOlsenDavidson1982, author = {Kliegl, Reinhold and Olsen, Richard K. and Davidson, Brian J.}, title = {Regression analyses as a tool for studying reading processes : comment on Just and Carpenter's eye fixation theory}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16857}, year = {1982}, abstract = {Just and Carpenter (1980) presented a theory of reading based on eye fixations wherein their "psycholinguistic" variables accounted for 72\% of the variance in word gaze durations. This comment raises some statistical and theoretical problems with their use of simultaneous regression analysis of gaze duration measures and with the resulting theory of reading. A major problem was the confounding of perceptual with psycholinguistic factors. New eye fixation data are presented to support these criticisms. Analysis of fixations within words revealed that most gaze duration variance was contributed by number of fixations rather than by fixation duration.}, language = {en} } @misc{FerenzPeterBerg1983, author = {Ferenz, Hans-J{\"u}rgen and Peter, Martin G. and Berg, Dieter}, title = {Inhibition of farnesoic acid methyltransferase by sinefungin}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17016}, year = {1983}, abstract = {Sinefungin inhibited the S-adenosylmethionine-dependent farnesoic acid methyltransferase in a cell-free system containing a homogenate of corpora allata from female locusts, Locusta migratoria. The enzyme catalyzed the penultimate step of juvenile hormone biosynthesis in the insects. Culturing corpora allata in the presence of sinefungin greatly suppressed juvenile hormone production. The following in vivo effects were visible after injection of the inhibitor: increase in mortality and reduction of total haemolymph protein liter and ovary fresh weight, as well as length of terminal oocytes. Attempts to reverse these effects by topical application of the juvenile hormone analog ZR-515 (methoprene) were only partly successful. Therefore, the in vivo effects may be due to a general inhibition of methyltransferase enzymes in the insect. Sinefungin appeared to be of potential interest as the first representative of a new class of insect growth regulators.}, language = {en} } @misc{KortPeterKoopmanschap1983, author = {Kort, C. A. D. de and Peter, Martin G. and Koopmanschap, A. B.}, title = {Binding and degradation of juvenile hormone III by haemolymph proteins of the Colorado potato beetle: a re-examination}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16777}, year = {1983}, abstract = {The haemolymph of the adult Colorado potato beetle, Lepinotarsa decemlineata Say, contains a high molecular weight (MW > 200,000) JH-III specific binding protein. The Kd value of the protein for racemic JH-III is 1.3 ± 0.2 × 10-7 M. It has a lower affinity for racemic JH-I and it does not bind JH-III-diol or JH-III-acid. The binding protein does discriminate between the enantiomers of synthetic, racemic JH-III as was determined by stereochemical anaysis of the bound and the free JH-III. Incubation of racemic JH-III with crude haemolymph results in preferential formation of (10S)-JH-III-acid, the unnatural configuration. The JH-esterase present in L. decemlineata haemolymph is not enantioselective. It is concluded that the most important function of the binding protein is that of a specific carrier, protecting the natural hormone against degradation by esterases. The carrier does not protect JH-I as efficiently as the lower homologue.}, language = {en} } @misc{OlsonKlieglDavidson1983, author = {Olson, Richard K. and Kliegl, Reinhold and Davidson, Brian J.}, title = {Eye Movements in Reading Disability}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-39880}, year = {1983}, abstract = {Contents: I. Introduction II. Word Coding Processes A. Word Recognition B. Orthographic Coding C. Phonological Coding III. Eye Monitor and Reading Task IV. Group Differences V. Dimensions of Individual Differences A. Regressive Fixation Index and Word Recognition B. Regressive Fixation Index and IQ C. Regressive Fixation Index and Saccade Length D. Regressive Fixation Index and Relative Phonological Skill VI. Multiple Regression Models of Individual Differences A. Disabled Readers in the Aloud Condition B. Disabled Readers in the Silent Condition C. Normal Readers in Silent and Aloud Conditions VII. Conclusions}, language = {en} } @misc{KlieglOlsonDavidson1983, author = {Kliegl, Reinhold and Olson, Richard K. and Davidson, Brian J.}, title = {On problems of unconfounding perceptual and language processes}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-39890}, year = {1983}, abstract = {Contents: I. Introduction II. Word Length and Word Frequency III. Preferred and Convenient Viewing Position IV. Influences across Words A. Serial Dependencies B. Lack of Saccadic Resilience V. Conclusion}, language = {en} } @misc{Hopf1983, author = {Hopf, Diether}, title = {Foreign worker's children in primary and secondary schools}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-35969}, year = {1983}, language = {en} }