@article{YangHuDingetal.2018,
  author    = {Yang, Guang and Hu, Rongting and Ding, Hong-ming and Kochovski, Zdravko and Mei, Shilin and Lu, Yan and Ma, Yu-qiang and Chen, Guosong and Jiang, Ming},
  title     = {CO2-switchable response of protein microtubules},
  series = {Materials chemistry frontiers},
  volume    = {2},
  journal   = {Materials chemistry frontiers},
  number    = {9},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {2052-1537},
  doi       = {10.1039/c8qm00245b},
  pages     = {1642 -- 1646},
  year      = {2018},
  abstract  = {Recently, we proposed a small molecular inducing ligand strategy to assemble proteins into highly-ordered structures via dual non-covalent interactions, i.e. carbohydrate-protein interaction and dimerization of Rhodamine B. Using this approach, artificial protein microtubules were successfully constructed. In this study, we find that these microtubules exhibit a perfect CO2 responsiveness; assembly and disassembly of these microtubules were nicely controlled by the alternative passage of CO2 and N-2. Upon the injection of CO2, a negative net-charged SBA turns into a neutral or positive net-charged SBA, which elongated, to some extent, the effective distance between SBA and Rhodamine B, resulting in the disassociation of the Rhodamine B dimer. Further experimental and simulation results reveal that the CO2-responsive mechanism differs from that of solubility change of the previously reported CO2-responsive synthetic materials.},
  language  = {en}
}