@article{DechBittmannSchaefer2020, author = {Dech, Silas and Bittmann, Frank and Schaefer, Laura}, title = {Behavior of oxygen saturation and blood filling in the venous capillary system of the biceps brachii muscle during a fatiguing isometric action}, series = {European Journal of Translational Myology}, volume = {30}, journal = {European Journal of Translational Myology}, number = {1}, publisher = {Unipress}, address = {Padova}, issn = {2037-7460}, doi = {10.4081/ejtm.2019.8800}, pages = {79 -- 87}, year = {2020}, abstract = {The objective of the study is to develop a better understanding of the capillary circulation in contracting muscles. Ten subjects were measured during a submaximal fatiguing isometric muscle action by use of the O2C spectrophotometer. In all measurements the capillary-venous oxygen saturation of hemoglobin (SvO2) decreases immediately after the start of loading and levels off into a steady state. However, two different patterns (type I and type II) emerged. They differ in the extent of deoxygenation (-10.37 ±2.59 percent points (pp) vs. -33.86 ±17.35 pp, P = .008) and the behavior of the relative hemoglobin amount (rHb). Type I reveals a positive rank correlation of SvO2 and rHb (? = 0.735, P <.001), whereas a negative rank correlation (? = -0.522, P <.001) occurred in type II, since rHb decreases until a reversal point, then increases averagely 13\% above the baseline value and levels off into a steady state. The results reveal that a homeostasis of oxygen delivery and consumption during isometric muscle actions is possible. A rough distinction in two types of regulation is suggested.}, language = {en} }