TY  - JOUR
A1  - Leimkühler, Silke
A1  - Lemaire, Olivier N.
A1  - Iobbi-Nivol, Chantal
T1  - Bacterial Molybdoenzymes
T2  - Molybdenum and tungsten enzymes : biochemistry
N2  - The biogenesis of molybdoenzymes is a cytoplasmic event requiring both the folded apoenzymes and the matured molybdenum cofactor. The structure and the complexity of the molybdenum cofactor varies in each molybdoenzyme family and consequently different accessory proteins are required for the maturation of the respective enzymes. Thus, for enzymes of both the DMSO reductase and xanthine oxidase families, specific chaperones exist which are dedicated to increase the stability and the folding of specific members of each family. In this review, we describe the role of these chaperones for molybdoenzyme maturation. We present a model which describes step by step the mechanism of the maturation of representative molybdoenzymes from each family.
Y1  - 2016
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/56212
SN  - 978-1-78262-391-5
SN  - 978-1-78262-089-1
VL  - 5
SP  - 117
EP  - 142
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  -