TY  - JOUR
A1  - Liu, Hsiang-chin
A1  - Lämke, Jörn
A1  - Lin, Siou-ying
A1  - Hung, Meng-Ju
A1  - Liu, Kuan-Ming
A1  - Charng, Yee-yung
A1  - Bäurle, Isabel
T1  - Distinct heat shock factors and chromatin modifications mediate the organ-autonomous transcriptional memory of heat stress
T2  - The plant journal
N2  - Plants can be primed by a stress cue to mount a faster or stronger activation of defense mechanisms upon subsequent stress. A crucial component of such stress priming is the modified reactivation of genes upon recurring stress; however, the underlying mechanisms of this are poorly understood. Here, we report that dozens of Arabidopsis thaliana genes display transcriptional memory, i.e. stronger upregulation after a recurring heat stress, that lasts for at least 3 days. We define a set of transcription factors involved in this memory response and show that the transcriptional memory results in enhanced transcriptional activation within minutes of the onset of a heat stress cue. Further, we show that the transcriptional memory is active in all tissues. It may last for up to a week, and is associated during this time with histone H3 lysine 4 hypermethylation. This transcriptional memory is cis-encoded, as we identify a promoter fragment that confers memory onto a heterologous gene. In summary, heat-induced transcriptional memory is a widespread and sustained response, and our study provides a framework for future mechanistic studies of somatic stress memory in higher plants.
KW  - epigenetics
KW  - priming
KW  - heat stress
KW  - H3K4 methylation
KW  - transcriptional memory
KW  - Arabidopsis thaliana
KW  - HSF
Y1  - 2018
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52422
SN  - 0960-7412
SN  - 1365-313X
VL  - 95
IS  - 3
SP  - 401
EP  - 413
PB  - Wiley
CY  - Hoboken
ER  -