TY - JOUR A1 - Verlinden, Heleen A1 - Vleugels, Rut A1 - Marchal, Elisabeth A1 - Badisco, Liesbeth A1 - Tobback, Julie A1 - Pflüger, Hans-Joachim A1 - Blenau, Wolfgang A1 - Vanden Broeck, Jozef T1 - The cloning, phylogenetic relationship and distribution pattern of two new putative GPCR-type octopamine receptors in the desert locust (Schistocerca gregaria) N2 - The biogenic amine octopamine functions as a neuromodulator, neurotransmitter and neurohormone in insect nervous systems. It plays a prominent role in modulating multiple physiological and behavioural processes in invertebrates. Octopamine exerts its effects by binding to specific receptor proteins that belong to the superfamily of G protein-coupled receptors. We found two partial sequences of putative octopamine receptors in the desert locust Schistocerca gregaria (SgOct alpha R and SgOct beta R) and investigated their transcript levels in males and females of both phases and during the transition between long-term solitarious and gregarious locusts. The transcript levels of SgOctaR are the highest in the central nervous system, whereas those of SgOct beta R are the highest in the flight muscles, followed by the central nervous system. Both SgOct alpha R and SgOct beta R show higher transcript levels in long-term gregarious locusts as compared to solitarious ones. The rise of SgOct beta R transcript levels already appears during the first 4 h of gregarisation, during which also the behavioural changes take place. Y1 - 2010 UR - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/31530 UR - http://www.sciencedirect.com/science/journal/00221910 SN - 0022-1910 ER -