TY  - JOUR
A1  - Schmidt, Bernd
A1  - Audörsch, Stephan
T1  - Stereoselective Total Syntheses of Polyacetylene Plant Metabolites via Ester-Tethered Ring Closing Metathesis
T2  - The journal of organic chemistry
N2  - Total syntheses of five naturally occurring polyacetylenes from three different plants are described. These natural products have in common an E,Z-configured conjugated diene linked to a di-or triyne chain. As the key method to stereoselectively establish the E,Z-diene part, an ester-tethered ring-closing metathesis/base-induced eliminative ring opening sequence was used. The results presented herein do not only showcase the utility of this tethered RCM variant but have also prompted us to suggest that the originally assigned absolute configurations of chiral polyacetylenes from Atractylodes macrocephala should be revised or at least reconsidered.
Y1  - 2017
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/55350
SN  - 0022-3263
VL  - 82
IS  - 3
SP  - 1743
EP  - 1760
PB  - American Chemical Society
CY  - Washington
ER  -