TY  - GEN
A1  - Westbury, Michael V.
A1  - Hartmann, Stefanie
A1  - Barlow, Axel
A1  - Wiesel, Ingrid
A1  - Leo, Viyanna
A1  - Welch, Rebecca
A1  - Parker, Daniel M.
A1  - Sicks, Florian
A1  - Ludwig, Arne
A1  - Dalen, Love
A1  - Hofreiter, Michael
T1  - Extended and continuous decline in effective population size results in low genomic diversity in the world's rarest hyena species, the brown hyena
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Hyenas (family Hyaenidae), as the sister group to cats (family Felidae), represent a deeply diverging branch within the cat-like carnivores (Feliformia). With an estimated population size of <10,000 individuals worldwide, the brown hyena (Parahyaena brunnea) represents the rarest of the four extant hyena species and has been listed as Near Threatened by the IUCN. Here, we report a high-coverage genome from a captive bred brown hyena and both mitochondrial and low-coverage nuclear genomes of 14 wild-caught brown hyena individuals from across southern Africa. We find that brown hyena harbor extremely low genetic diversity on both the mitochondrial and nuclear level, most likely resulting from a continuous and ongoing decline in effective population size that started similar to 1 Ma and dramatically accelerated towards the end of the Pleistocene. Despite the strikingly low genetic diversity, we find no evidence of inbreeding within the captive bred individual and reveal phylogeographic structure, suggesting the existence of several potential subpopulations within the species.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 589 
KW  - evolution
KW  - hyena
KW  - genomics
KW  - population genomics
KW  - diversity
Y1  - 2019
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/41413
UR  - https://nbn-resolving.org/urn:nbn:de:kobv:517-opus4-414132
SN  - 1866-8372
IS  - 589
ER  -