TY  - JOUR
A1  - Schedlbauer, Carola
A1  - Blaue, Dominique
A1  - Raila, Jens
A1  - Vervuert, Ingrid
T1  - Alterations of serum vitamin E and vitamin A concentrations of ponies and horses during experimentally induced obesity
T2  - Journal of animal physiology and animal nutrition
T2  - Zeitschrift für Tierphysiologie, Tierernährung und Futtermittelkunde
N2  - Vitamin A, vitamin E and retinol-binding protein 4 (RBP4) are a focus of current obesity research in humans. The impact of body weight (BW) gain on fat-soluble vitamins and its associated parameters in equines has not been previously reported. Ten Shetland ponies and 9 Warmblood horses, all adult geldings, non-obese and healthy, were fed an excessive energy diet for 20 months to induce BW gain. Serum alpha-tocopherol (vitamin E), retinol (vitamin A), retinol-binding protein 4 (RBP4) and retinol/RBP4 ratio were analysed before BW gain induction and at six timepoints during the BW gaining period. The mean (+/- SD) % BW gain achieved during two years of excess energy intake was 29.9 +/- 19.4% for ponies and 17 +/- 6.74% for horses. Serum alpha-tocopherol increased significantly in ponies and horses during excess energy intake and circulating alpha-tocopherol levels correlated positively with alpha-tocopherol intake (r = .6; p < .001). Serum retinol concentrations showed variations during the study but without relation to intake. Serum RBP4 decreased at the end of the study. The retinol/RBP4 ratio increased with BW gain without differences between ponies and horses. In comparison with human research, the increase in the retinol/RBP4 ratio was unexpected and needs further elucidation.
KW  - body weight gain
KW  - equine
KW  - laminitis
KW  - retinol-binding protein 4
KW  - alpha-tocopherol
Y1  - 2020
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/58571
SN  - 0931-2439
SN  - 1439-0396
VL  - 104
IS  - 5
SP  - 1501
EP  - 1508
PB  - Wiley
CY  - Hoboken
ER  -