TY  - JOUR
A1  - Koehler, Friedrich
A1  - Koehler, Kerstin
A1  - Deckwart, Oliver
A1  - Prescher, Sandra
A1  - Wegscheider, Karl
A1  - Winkler, Sebastian
A1  - Vettorazzi, Eik
A1  - Polze, Andreas
A1  - Stangl, Karl
A1  - Hartmann, Oliver
A1  - Marx, Almuth
A1  - Neuhaus, Petra
A1  - Scherf, Michael
A1  - Kirwan, Bridget-Anne
A1  - Anker, Stefan D.
T1  - Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients
T2  - European Journal of Heart Failure
N2  - Background Heart failure (HF) is a complex, chronic condition that is associated with debilitating symptoms, all of which necessitate close follow-up by health care providers. Lack of disease monitoring may result in increased mortality and more frequent hospital readmissions for decompensated HF. Remote patient management (RPM) in this patient population may help to detect early signs and symptoms of cardiac decompensation, thus enabling a prompt initiation of the appropriate treatment and care before a manifestation of HF decompensation. Objective The objective of the present article is to describe the design of a new trial investigating the impact of RPM on unplanned cardiovascular hospitalisations and mortality in HF patients. Methods The TIM-HF2 trial is designed as a prospective, randomised, controlled, parallel group, open (with randomisation concealment), multicentre trial with pragmatic elements introduced for data collection. Eligible patients with HF are randomised (1:1) to either RPM + usual care or to usual care only and are followed for 12 months. The primary outcome is the percentage of days lost due to unplanned cardiovascular hospitalisations or all-cause death. The main secondary outcomes are all-cause and cardiovascular mortality. Conclusion The TIM-HF2 trial will provide important prospective data on the potential beneficial effect of telemedical monitoring and RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.
KW  - Chronic heart failure
KW  - Telemonitoring
KW  - Remote patient management
KW  - Hospitalisation
Y1  - 2018
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/51826
SN  - 1388-9842
SN  - 1879-0844
VL  - 20
IS  - 10
SP  - 1485
EP  - 1493
PB  - Wiley
CY  - Hoboken
ER  -