TY  - JOUR
A1  - Konrad, Marcel
A1  - Jacob, Louis
A1  - Rapp, Michael Armin
A1  - Kostev, Karel
T1  - Depression risk in patients with coronary heart disease in Germany
T2  - World Journal of Cardiology
N2  - AIM To determine the prevalence of depression and its risk factors among patients with coronary heart disease (CHD) treated in German primary care practices. METHODS Longitudinal data from nationwide general practices in Germany (n = 1072) were analyzed. Individuals initially diagnosed with CHD (2009-2013) were identified, and 59992 patients were included and matched (1: 1) to 59992 controls. The primary outcome measure was an initial diagnosis of depression within five years after the index date among patients with and without CHD. Cox proportional hazards models were used to adjust for confounders. RESULTS Mean age was equal to 68.0 years (SD = 11.3). A total of 55.9% of patients were men. After a five-year follow-up, 21.8% of the CHD group and 14.2% of the control group were diagnosed with depression (P < 0.001). In the multivariate regression model, CHD was a strong risk factor for developing depression (HR = 1.54, 95% CI: 1.49-1.59, P < 0.001). Prior depressive episodes, dementia, and eight other chronic conditions were associated with a higher risk of developing depression. Interestingly, older patients and women were also more likely to be diagnosed with depression compared with younger patients and men, respectively. CONCLUSION The risk of depression is significantly increased among patients with CHD compared with patients without CHD treated in primary care practices in Germany. CHD patients should be routinely screened for depression to ensure improved treatment and management.
KW  - Coronary heart disease
KW  - Depression
KW  - Primary care
KW  - Risk factors
KW  - Quality of life
Y1  - 2016
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/45009
SN  - 1949-8462
VL  - 8
SP  - 547
EP  - 552
PB  - Baishideng Publishing Group
CY  - Pleasanton
ER  -