TY  - GEN
A1  - Niedl, Robert Raimund
A1  - Beta, Carsten
T1  - Hydrogel-driven paper-based microfluidics
N2  - Paper-based microfluidics provide an inexpensive, easy to use technology for point-of-care diagnostics in developing countries. Here, we combine paper-based microfluidic devices with responsive hydrogels to add an entire new class of functions to these versatile low-cost fluidic systems. The hydrogels serve as fluid reservoirs. In response to an external stimulus, e.g. an increase in temperature, the hydrogels collapse and release fluid into the structured paper substrate. In this way, chemicals that are either stored on the paper substrate or inside the hydrogel pads can be dissolved, premixed, and brought to reaction to fulfill specific analytic tasks. We demonstrate that multi-step sequences of chemical reactions can be implemented in a paper-based system and operated without the need for external precision pumps. We exemplify this technology by integrating an antibody-based E. coli test on a small and easy to use paper device.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 193 
Y1  - 2015
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/8108
UR  - https://nbn-resolving.org/urn:nbn:de:kobv:517-opus4-81083
SP  - 2452
EP  - 2459
ER  -