TY  - JOUR
A1  - Rumschoettel, Jens
A1  - Kosmella, Sabine
A1  - Prietzel, Claudia Christina
A1  - Appelhans, Dietmar
A1  - Koetz, Joachim
T1  - DNA polyplexes with dendritic glycopolymer-entrapped gold nanoparticles
T2  - Colloids and surfaces : an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin ; B, Biointerfaces
N2  - Polyplexes, composed of Salmon DNA and very small gold nanoparticles embedded into a dendritic glycopolymer architecture of sugar-modified poly(ethyleneimine) (PEI-Mal) with a molar mass of about 25,000 g/mol, were characterized by dynamic light scattering (DLS), zeta potential measurements, micro differential scanning calorimetry (mu-DSC) and transmission electron microscopy (TEM). The PEI-Mal-entrapped gold nanoparticles of about 2 nm in diameter influence the polyplex formation of the hyperbranched PEI containing bulky maltose, and in consequence the DNA is more compactized in the inner part of spherical polyplex particles of about 150 nm in diameter. The resulting more compact core shell polyplex particles with embedded gold nanoparticles in the outer polymer shell will be used as components in forthcoming gene delivery experiments. (C) 2017 Elsevier B.V. All rights reserved.
KW  - DNA polyplexes
KW  - Gold nanoparticles
KW  - Maltose-modified poly(ethyleneimine)
KW  - TEM
KW  - mu-DSC
Y1  - 2017
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/46623
SN  - 0927-7765
SN  - 1873-4367
VL  - 154
SP  - 74
EP  - 81
PB  - Elsevier
CY  - Amsterdam
ER  -