TY  - GEN
A1  - Zwickel, Theresa
A1  - Kahl, Sandra M.
A1  - Rychlik, Michael
A1  - Müller, Marina E. H.
T1  - Chemotaxonomy of mycotoxigenic small-spored Alternaria fungi
T2  - Postprints der Universität Potsdam Mathematisch-Naturwissenschaftliche Reihe
N2  - Necrotrophic as well as saprophytic small-spored Altemaria (A.) species are annually responsible for major losses of agricultural products, such as cereal crops, associated with the contamination of food and feedstuff with potential health-endangering Altemaria toxins. Knowledge of the metabolic capabilities of different species-groups to form mycotoxins is of importance for a reliable risk assessment. 93 Altemaria strains belonging to the four species groups Alternaria tenuissima, A. arborescens, A. altemata, and A. infectoria were isolated from winter wheat kernels harvested from fields in Germany and Russia and incubated under equal conditions. Chemical analysis by means of an HPLC-MS/MS multi-Alternaria-toxin-method showed that 95% of all strains were able to form at least one of the targeted 17 non-host specific Altemaria toxins. Simultaneous production of up to 15 (modified) Altemaria toxins by members of the A. tenuissima, A. arborescens, A. altemata species-groups and up to seven toxins by A. infectoria strains was demonstrated. Overall tenuazonic acid was the most extensively formed mycotoxin followed by alternariol and alternariol mono methylether, whereas altertoxin I was the most frequently detected toxin. Sulfoconjugated modifications of alternariol, alternariol mono methylether, altenuisol and altenuene were frequently determined. Unknown perylene quinone derivatives were additionally detected. Strains of the species-group A. infectoria could be segregated from strains of the other three species-groups due to significantly lower toxin levels and the specific production of infectopyrone. Apart from infectopyrone, alterperylenol was also frequently produced by 95% of the A. infectoria strains. Neither by the concentration nor by the composition of the targeted Altemaria toxins a differentiation between the species-groups A. altemata, A. tenuissima and A. arborescens was possible.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 696 
KW  - small-spored Alternaria fungi
KW  - Alternaria species-groups
KW  - Alternaria mycotoxins
KW  - chemotaxonomy
KW  - secondary metabolite profiling
KW  - LC-MS/MS
KW  - wheat
KW  - perylene quinone derivatives
Y1  - 2019
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/42662
UR  - https://nbn-resolving.org/urn:nbn:de:kobv:517-opus4-426623
SN  - 1866-8372
IS  - 696
ER  -