TY  - JOUR
A1  - Saparin, P. I.
A1  - Thomsen, J. S.
A1  - Prohaska, Steffen
A1  - Zaikin, Alexei
A1  - Kurths, Jürgen
A1  - Hege, H. C.
A1  - Gowin, W.
T1  - Quantification of spatial structure of human proximal tibial bone biopsies using 3D measures of complexity
N2  - Changes in trabecular bone composition during development of osteoporosis are used as a model for bone loss in microgravity conditions during a space flight. Symbolic dynamics and measures of complexity are proposed and applied to assess quantitatively the structural composition of bone tissue from 3D data sets of human tibia bone biopsies acquired by a micro-CT scanner. In order to justify the newly proposed approach, the measures of complexity of the bone architecture were compared with the results of traditional 2D bone histomorphometry. The proposed technique is able to quantify the structural loss of the bone tissue and may help to diagnose and to monitor changes in bone structure of patients on Earth as well as of the space-flying personnel. © 2005 Elsevier Ltd. All rights reserved
Y1  - 2005
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/13855
SN  - 0094-5765
ER  -