TY - JOUR A1 - Volk, Christin A1 - Brandsch, Corinna A1 - Schlegelmilch, Ulf A1 - Wensch-Dorendorf, Monika A1 - Hirche, Frank A1 - Simm, Andreas A1 - Gargum, Osama A1 - Wiacek, Claudia A1 - Braun, Peggy G. A1 - Kopp, Johannes F. A1 - Schwerdtle, Tanja A1 - Treede, Hendrik A1 - Stangl, Gabriele I. T1 - Postprandial metabolic response to rapeseed protein in healthy subjects T2 - Nutrients N2 - Plant proteins have become increasingly important for ecological reasons. Rapeseed is a novel source of plant proteins with high biological value, but its metabolic impact in humans is largely unknown. A randomized, controlled intervention study including 20 healthy subjects was conducted in a crossover design. All participants received a test meal without additional protein or with 28 g of rapeseed protein isolate or soy protein isolate (control). Venous blood samples were collected over a 360-min period to analyze metabolites; satiety was assessed using a visual analog scale. Postprandial levels of lipids, urea, and amino acids increased following the intake of both protein isolates. The postprandial insulin response was lower after consumption of the rapeseed protein than after intake of the soy protein (p< 0.05), whereas the postmeal responses of glucose, lipids, interleukin-6, minerals, and urea were comparable between the two protein isolates. Interestingly, the rapeseed protein exerted stronger effects on postprandial satiety than the soy protein (p< 0.05). The postmeal metabolism following rapeseed protein intake is comparable with that of soy protein. The favorable effect of rapeseed protein on postprandial insulin and satiety makes it a valuable plant protein for human nutrition. KW - rapeseed protein KW - soy protein KW - postprandial study KW - metabolic response KW - healthy subjects Y1 - 2020 UR - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/61202 SN - 2072-6643 VL - 12 IS - 8 PB - MDPI CY - Basel ER -