TY  - JOUR
A1  - Doering, Ulrike
A1  - Grigoriev, Dmitry
A1  - Tapio, Kosti
A1  - Rosencrantz, Sophia
A1  - Rosencrantz, Ruben R.
A1  - Bald, Ilko
A1  - Böker, Alexander
T1  - About the mechanism of ultrasonically induced protein capsule formation
T2  - RSC Advances : an international journal to further the chemical sciences / Royal Society of Chemistry
N2  - In this paper, we propose a consistent mechanism of protein microcapsule formation upon ultrasound treatment. Aqueous suspensions of bovine serum albumin (BSA) microcapsules filled with toluene are prepared by use of high-intensity ultrasound following a reported method. Stabilization of the oil-in-water emulsion by the adsorption of the protein molecules at the interface of the emulsion droplets is accompanied by the creation of the cross-linked capsule shell due to formation of intermolecular disulfide bonds caused by highly reactive species like superoxide radicals generated sonochemically. The evidence for this mechanism, which until now remained elusive and was not proven properly, is presented based on experimental data from SDS-PAGE, Raman spectroscopy and dynamic light scattering.
Y1  - 2021
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/60830
SN  - 2046-2069
VL  - 11
IS  - 27
SP  - 16152
EP  - 16157
PB  - RSC Publishing
CY  - London
ER  -