TY  - GEN
A1  - Gräf, Ralph
T1  - Comparative Biology of Centrosomal Structures in Eukaryotes
T2  - Cells
N2  - The centrosome is not only the largest and most sophisticated protein complex within a eukaryotic cell, in the light of evolution, it is also one of its most ancient organelles. This special issue of "Cells" features representatives of three main, structurally divergent centrosome types, i.e., centriole-containing centrosomes, yeast spindle pole bodies (SPBs), and amoebozoan nucleus-associated bodies (NABs). Here, I discuss their evolution and their key-functions in microtubule organization, mitosis, and cytokinesis. Furthermore, I provide a brief history of centrosome research and highlight recently emerged topics, such as the role of centrioles in ciliogenesis, the relationship of centrosomes and centriolar satellites, the integration of centrosomal structures into the nuclear envelope and the involvement of centrosomal components in non-centrosomal microtubule organization.
KW  - centrosome
KW  - centriole
KW  - cilium
KW  - basal body
KW  - spindle pole body
KW  - SPB
KW  - nucleus-associated body
KW  - NAB
KW  - microtubules
Y1  - 2018
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/51319
SN  - 2073-4409
VL  - 7
IS  - 11
PB  - MDPI
CY  - Basel
ER  -