TY  - JOUR
A1  - Tucker, Marlee A.
A1  - Boehning-Gaese, Katrin
A1  - Fagan, William F.
A1  - Fryxell, John M.
A1  - Van Moorter, Bram
A1  - Alberts, Susan C.
A1  - Ali, Abdullahi H.
A1  - Allen, Andrew M.
A1  - Attias, Nina
A1  - Avgar, Tal
A1  - Bartlam-Brooks, Hattie
A1  - Bayarbaatar, Buuveibaatar
A1  - Belant, Jerrold L.
A1  - Bertassoni, Alessandra
A1  - Beyer, Dean
A1  - Bidner, Laura
A1  - van Beest, Floris M.
A1  - Blake, Stephen
A1  - Blaum, Niels
A1  - Bracis, Chloe
A1  - Brown, Danielle
A1  - de Bruyn, P. J. Nico
A1  - Cagnacci, Francesca
A1  - Calabrese, Justin M.
A1  - Camilo-Alves, Constanca
A1  - Chamaille-Jammes, Simon
A1  - Chiaradia, Andre
A1  - Davidson, Sarah C.
A1  - Dennis, Todd
A1  - DeStefano, Stephen
A1  - Diefenbach, Duane
A1  - Douglas-Hamilton, Iain
A1  - Fennessy, Julian
A1  - Fichtel, Claudia
A1  - Fiedler, Wolfgang
A1  - Fischer, Christina
A1  - Fischhoff, Ilya
A1  - Fleming, Christen H.
A1  - Ford, Adam T.
A1  - Fritz, Susanne A.
A1  - Gehr, Benedikt
A1  - Goheen, Jacob R.
A1  - Gurarie, Eliezer
A1  - Hebblewhite, Mark
A1  - Heurich, Marco
A1  - Hewison, A. J. Mark
A1  - Hof, Christian
A1  - Hurme, Edward
A1  - Isbell, Lynne A.
A1  - Janssen, Rene
A1  - Jeltsch, Florian
A1  - Kaczensky, Petra
A1  - Kane, Adam
A1  - Kappeler, Peter M.
A1  - Kauffman, Matthew
A1  - Kays, Roland
A1  - Kimuyu, Duncan
A1  - Koch, Flavia
A1  - Kranstauber, Bart
A1  - LaPoint, Scott
A1  - Leimgruber, Peter
A1  - Linnell, John D. C.
A1  - Lopez-Lopez, Pascual
A1  - Markham, A. Catherine
A1  - Mattisson, Jenny
A1  - Medici, Emilia Patricia
A1  - Mellone, Ugo
A1  - Merrill, Evelyn
A1  - Mourao, Guilherme de Miranda
A1  - Morato, Ronaldo G.
A1  - Morellet, Nicolas
A1  - Morrison, Thomas A.
A1  - Diaz-Munoz, Samuel L.
A1  - Mysterud, Atle
A1  - Nandintsetseg, Dejid
A1  - Nathan, Ran
A1  - Niamir, Aidin
A1  - Odden, John
A1  - Oliveira-Santos, Luiz Gustavo R.
A1  - Olson, Kirk A.
A1  - Patterson, Bruce D.
A1  - de Paula, Rogerio Cunha
A1  - Pedrotti, Luca
A1  - Reineking, Bjorn
A1  - Rimmler, Martin
A1  - Rogers, Tracey L.
A1  - Rolandsen, Christer Moe
A1  - Rosenberry, Christopher S.
A1  - Rubenstein, Daniel I.
A1  - Safi, Kamran
A1  - Said, Sonia
A1  - Sapir, Nir
A1  - Sawyer, Hall
A1  - Schmidt, Niels Martin
A1  - Selva, Nuria
A1  - Sergiel, Agnieszka
A1  - Shiilegdamba, Enkhtuvshin
A1  - Silva, Joao Paulo
A1  - Singh, Navinder
A1  - Solberg, Erling J.
A1  - Spiegel, Orr
A1  - Strand, Olav
A1  - Sundaresan, Siva
A1  - Ullmann, Wiebke
A1  - Voigt, Ulrich
A1  - Wall, Jake
A1  - Wattles, David
A1  - Wikelski, Martin
A1  - Wilmers, Christopher C.
A1  - Wilson, John W.
A1  - Wittemyer, George
A1  - Zieba, Filip
A1  - Zwijacz-Kozica, Tomasz
A1  - Mueller, Thomas
T1  - Moving in the Anthropocene
BT  - global reductions in terrestrial mammalian movements
JF  - Science
N2  - Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission.
Y1  - 2018
U6  - https://doi.org/10.1126/science.aam9712
SN  - 0036-8075
SN  - 1095-9203
VL  - 359
IS  - 6374
SP  - 466
EP  - 469
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - CHAP
A1  - Kirk, John M.
A1  - Kallen, Jeffrey L.
T1  - Assessing Celticity in a corpus of Irish Standard English
N2  - Conventional wisdom since the earliest studies of Irish English has attributed much of what is distinctive about this variety to the influence of the Irish language. From the early philologists (Joyce 1910, van Hamel 1912) through the classic works of Henry (1957, 1958) and Bliss (1979) down to present-day linguistic orientations (e.g. Corrigan 2000 a, Filppula 1999, Fiess 2000, Hickey 2000, Todd 1999, and others), the question of Irish-language influence may be disputed on points of detail, but remains a central focus for most studies in the field. It is not our intention to argue with this consensus, nor to examine specific points of grammar in detail, but, rather, to suggest an approach to this question which (a) takes for its empirical base a sample of the standard language, rather than dialectal material or the sample sentences so beloved of many papers on the subject, and (b) understands Celticity not just in terms of the formal transfer of grammatical features, but as an indexical feature of language use, i.e. one in which English in Ireland is used in such a way as to point to the Irish language as a linguistic and cultural reference point. In this sense, our understanding of Celticity is not entirely grammatical, but relies as well on Pierce’s notion of indexicality (see Greenlee 1973), by which semiotic signs ‘point to’ other signs. Our focus in assessing Celticity, then, derives in the first instance from an examination of the International Corpus of English (ICE). We have recently completed the publication of the Irish component of ICE (ICE-Ireland), a machinereadable corpus of over 1 million words of speech and writing gathered from a range of contexts determined by the protocols of the global International Corpus of English project. The international nature of this corpus project makes for ready comparisons with other varieties of English, and in this paper we will focus on comparisons with the British corpus, ICE-GB. For references on ICE generally, see Greenbaum 1996; for ICE-GB, see especially Nelson, Wallis and Aarts 2002; and for ICE-Ireland, see papers such as Kirk, Kallen, Lowry & Rooney (2003), Kirk & Kallen (2005), and Kallen & Kirk (2007). Our first approach will be to look for signs of overt Celticity in those grammatical features of Irish English which have been put forward as evidence of Celtic transfer (or of the reinforcement between Celtic and non-Celtic historical sources); our second approach will be to look at non-grammatical ways in which texts in ICEIreland become indexical of Celticity by less structural means such as loanwords, code-switching, and covert reference using ‘standard’ English in ways that are specific to Irish usage. We argue that, at least within the standard language as we have observed it, Celticity is at once less obvious than a reading of the dialectal literature might suggest and, at the same time, more pervasive than a purely grammatical approach would imply.
Y1  - 2007
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-19349
ER  - 
TY  - JOUR
A1  - Lim, Sze Chern
A1  - Friemel, Martin
A1  - Marum, Justine E.
A1  - Tucker, Elena J.
A1  - Bruno, Damien L.
A1  - Riley, Lisa G.
A1  - Christodoulou, John
A1  - Kirk, Edwin P.
A1  - Boneh, Avihu
A1  - DeGennaro, Christine M.
A1  - Springer, Michael
A1  - Mootha, Vamsi K.
A1  - Rouault, Tracey A.
A1  - Leimkühler, Silke
A1  - Thorburn, David R.
A1  - Compton, Alison G.
T1  - Mutations in LYRM4, encoding ironsulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes
JF  - Human molecular genetics
N2  - Ironsulfur clusters (ISCs) are important prosthetic groups that define the functions of many proteins. Proteins with ISCs (called ironsulfur or FeS proteins) are present in mitochondria, the cytosol, the endoplasmic reticulum and the nucleus. They participate in various biological pathways including oxidative phosphorylation (OXPHOS), the citric acid cycle, iron homeostasis, heme biosynthesis and DNA repair. Here, we report a homozygous mutation in LYRM4 in two patients with combined OXPHOS deficiency. LYRM4 encodes the ISD11 protein, which forms a complex with, and stabilizes, the sulfur donor NFS1. The homozygous mutation (c.203GT, p.R68L) was identified via massively parallel sequencing of 1000 mitochondrial genes (MitoExome sequencing) in a patient with deficiency of complexes I, II and III in muscle and liver. These three complexes contain ISCs. Sanger sequencing identified the same mutation in his similarly affected cousin, who had a more severe phenotype and died while a neonate. Complex IV was also deficient in her skeletal muscle. Several other FeS proteins were also affected in both patients, including the aconitases and ferrochelatase. Mutant ISD11 only partially complemented for an ISD11 deletion in yeast. Our in vitro studies showed that the l-cysteine desulfurase activity of NFS1 was barely present when co-expressed with mutant ISD11. Our findings are consistent with a defect in the early step of ISC assembly affecting a broad variety of FeS proteins. The differences in biochemical and clinical features between the two patients may relate to limited availability of cysteine in the newborn period and suggest a potential approach to therapy.
Y1  - 2013
U6  - https://doi.org/10.1093/hmg/ddt295
SN  - 0964-6906
SN  - 1460-2083
VL  - 22
IS  - 22
SP  - 4460
EP  - 4473
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Kirk, John M.
A1  - Kallen, Jeffrey L.
T1  - Irish standard English
BT  - how celticised?; how standardised?
JF  - The Celtic Englishes IV : the interface between English and the Celtic languages ; proceedings of the fourth international colloquium on the "Celtic Englishes" held at the University of Potsdam in Golm (Germany) from 22-26 September 2004
N2  - Content: 1. Introduction 2. ICE-Ireland and the Irish Language 3. Grammatical Features 3.1. Perfective Aspect 3.2. Reflexive Pronouns 3.3. Inversion and Embedded Clauses 4. Conclusion
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-40948
SP  - 88
EP  - 113
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  -